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Letustalkthefirstquestion:HowTotakeNMNpowder?
www.aasraw.com In last question, we mentioned Dr. David Sinclair who has taken 1g NMN every day. Then 1g be the most effective dosage for us to get the benefits of NMN, right? “Certainly not!” When working out how much you need to take, it’s important to consider how the NMN is administered and its bioavailability. What’s more, different body with different reaction. We need make out when it is good to take NMN, how to take it and how much dose we should take when you ready to take NMN powder.
Letustalkthefirstquestion:HowTotakeNMN powder?
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NMN is administered in four options that will affect how much NMN actually makes it into your blood system: powder, sublingual powder, standard capsules, and gastric-resistant capsules.
To understand bioavailability, one has to understand the First Pass Effect(it refers to how much of a substance is destroyed or processed by the liver before it actually passes into the blood system). This is the complicated concept, I guess this video can help us to understand how it works and why it is very important for us to know it before taking NMN powder. Because of the first-pass metabolism, oral consumption of NMN is much less effective than sublingual or gastro-resistant capsules. When NMN powder is taken orally (either when eaten or mixed with a liquid) most of it is destroyed by the stomach acid. The remaining NMN is then metabolized by the liver. How the liver metabolizes NMN can have a huge impact on bioavailability. It may be that only a fraction of NMN actually makes it into your system. Also to improve your NAD+ levels, you can take the delayed-release NMN capsules with a Sirtuin Activator such as a Resveratrol with a full-fat yogurt which helps the bioavailability of Resveratrol.
But when NMN (or any medication or supplement) is taken sublingually, it is absorbed across the mucous membranes (under the
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