M A N U F A C T U R I N G
Pharma 4.0: Advanced Continuous Pharmaceutical Tablet Manufacturing Pharma 4.0, an application of Industry 4.0 concepts in the pharmaceutical industry, aims to enhance manufacturing efficiency, product quality, and consistency. It faces challenges in areas like artificial intelligence, material traceability, optimization, process control, cyber-physical security, and data management due to the complexity involved. However, by incorporating artificial intelligence and advanced model predictive control with robust cyberphysical security measures, predictive capabilities and product quality can be significantly improved. This work focuses on implementing seven Industry 4.0 components, including AI/ML, modeling, material traceability, optimization, advanced control, cyber-physical security, and data science, in continuous pharmaceutical manufacturing processes.
Ravendra Singh C-SOPS, Department of Chemical and Biochemical Engineering, Rutgers, The State University of New Jersey USA
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P H AR M A F O C U S E U R O PE
ISSUE 02 - 2023
C
urrently, Industry 4.0 concepts are being applied to the pharmaceutical industry to achieve Pharma 4.0 paradigm. It is promoted by industries, academia and regulators. Pharma 4.0 reduces the time and resources needed for continuous pharmaceutical manufacturing and improves product quality and production consistency. It has many advantages but also have bigger challenges on the applications