v i CTorian Brain Bank n e TWork

Division head: Professor Catriona McLean AIMS

The Victorian Brain Bank Network (VBBN) collects, processes and stores post-mortem human brains and related samples from individuals who have had neurological diseases (i.e. Alzheimer’s disease, motor neurone disease and Parkinson’s disease), physichiatric disorders (i.e. bipolar mood disorder, depression and schizophrenia) as well as normal ‘control’ cases. The VBBN facilitates research into the study of brain diseases by providing tissue to researchers who, using current technologies, aim to unlock our understanding of how brain diseases occur and this will hopefully lead to improvements in diagnosis, the development of early diagnostic tests, therapeutic interventions and development of preventative strategies. We provide a vital and unique neuropathological diagnostic service that confirms a ante-mortem clinical diagnosis, increases clinicians’ awareness and understanding of atypical presentations of certain brain diseases, confirms a diagnosis for donor families, in whom neurological disease may have hereditary or familial association and may be at risk of developing the disease, generates pathological description of brain diseases and advances knowledge of some brain pathologies, thus providing a powerful tool for education and research and importantly, this service is relied on for the validation of research studies.

ACKNO w LEDGMENT

The VBBN would like to acknowledge the generosity shown by the donor and donor families in donating tissue to the VBBN. It is an act of great foresight and kindness to give at a time of loss, so that others may be helped in the future. The clinicians and researchers who benefit from these donations are very grateful to the donors and their families who support them in these decisions.

The VBBN would like to acknowledge the support of the following funeral directors, Bethel, Jensen, Allison Monkhouse, Le Pine, Nelson Bros, Tobin Brothers and WD Rose & Joseph Allison who provide metropolitan transfers for tissue retrieval at no cost to the VBBN.

Highlights

BRAIN AND BRAIN/ SPINAL CORD DONATIONS

The VBBN has a total of 1,093 cases available for research, with 54 new donations received in 2013. The new donations included cases diagnosed with Alzheimer’s disease, Frontotemporal dementia, Huntington’s disease, Lewy body disease, Motor neurone disease, Multiple sclerosis, Parkinson’s disease, schizophrenia, and control ‘normal’ cases. The VBBN collection makes up 39% of the cases that are available for research within Australia.

Tissues Provided To Researchers

During 2013, the VBBN provided tissue to 47 Australian and international new or continuing research projects, with the main research focus being Alzheimer’s disease, Motor neurone disease, schizophrenia and bipolar disorder. This equates to 3,217 diseased and ‘control’ samples being provided to researchers.

Research groups at The Florey Institute of Neuroscience and Mental Health are among the recipients of this tissue. Seven new research groups have accessed tissues from the VBBN this year with research being performed at Monash University, Murdoch Children’s Research Institute, The Florey Institute of Neuroscience and Mental Health, Kyung Hee University, Korea and Kyungpook National University, Korea.

During 2013 research utilising tissue from the VBBN has resulted in 61 Australian and International publications and presentations.

HEAD

Professor Catriona A McLean BSc, MBBS, FRCPA, MD, FFSc (RCPA)

DIRECTOR

Professor Brian Dean HND ApplBiol, MSc, PhD, Fl Biol

SENIOR STAFF

CONSULTANTS

Professor Colin Masters BMedSc (Hons), MBBS, MD, HonDLitt WAust, FRCPath, FRACPA, FAA, FTSE

Associate Professor Suresh Sundram MBBS, MMed, FRANZCP, PhD

Collaborators

COORDINATOR

Ms Fairlie Hinton

RESEARCH ASSISTANT

Mr Geoff Pavey BSc (Hons)

CONSULTANT HISTOLOGIST

Dr Ian Birchall BAppSc, MSc, PhD

• Laboratory Manager and Mortuary Technicians, The Alfred • Pathologists and Mortuary Technicians at the Victorian Institute of Forensic Medicine • Ballarat Health Services, Bendigo Health, Royal Hobart Hospital and Launceston General Hospital

• Transplant and Family Liaison Coordinators at the Donor Tissue Bank of Victoria • ҩ Andrew Abercrombie ҩ Charles Allen AO ҩ James Angus AO ҩ Etienne Baulieu ҩ Samuel Berkovic AC ҩ Chris Blake ҩ Neal Blewett AC ҩ Graeme Bowker ҩ Di Bresciani OAM ҩ Alec Broers ҩ Graham Brooke AM ҩ Malcolm Broomhead ҩ John Brumby ҩ Tom Buchan ҩ Geoffrey Burnstock ҩ Richard Buxton ҩ Edward Byrne AO ҩ Hon Jim Carlton ҩ Peter Castaldi ҩ Jean-Pierre Changeux ҩ Trevor Clark OAM ҩ Peter Clemenger ҩ John Coghlan ҩ David Copolov ҩ Philip Cornish ҩ Charles Curwen DVO OBE ҩ Andrew Cuthbertson ҩ Tim Daly AM ҩ Stephen Davis ҩ Jerry de la Harpe ҩ David de Rothschild ҩ David de Souza AM ҩ Derek Denton AC ҩ Peter Doherty AC ҩ Ralph Doherty AO ҩ Suzanne Downes ҩ Craig Drummond ҩ George Fink ҩ Alan Finkel AM ҩ John Finlay-Jones ҩ Roger Flynn ҩ Malcolm Fraser AC CH ҩ Tamie Fraser AO ҩ Peter Fuller ҩ John Funder ҩ Rob Gerrand ҩ Bruce Kean AM ҩ John Kearney AM QC (dec 2/10/2013) ҩ Anne Kelso AO ҩ Bruce Kemp ҩ Jennifer Labourne ҩ Frank Larkins ҩ Richard Larkins AO ҩ John Lill OAM ҩ Paul Little AO ҩ Bernard Lochtenberg

In October, 2013, the Florey named its auditorium in Parkville after one of its founding fathers, Sir Ian Potter. In attendance on the day was his widow, Lady (Primrose) Potter AC, pictured.

The Florey’s chairman, Harold Mitchell AC, remembered Sir Ian as an extraordinary man, a visionary business leader, a confidant to many and a great philanthropist.

Sir Ian, along with the legendary Professor Derek Denton AC, worked with Ken Myer AC, and Baillieu Myer AC, to help establish the Howard Florey Institute which opened in 1963. Fifty years later, the Florey is one of the most cited neuroscience organisations in the world – thanks, in part, to philanthropic support from the great Potter and Myer families and their foundations.

Florey g overnors

ҩ Charles Goode AC ҩ Susan Greenfield CBE ҩ Helen Groves AO ҩ Sandra Hacker AO ҩ Michael Hamson ҩ Arnold Hancock OBE ҩ Pamela Hauser ҩ Caroline Hogg ҩ Andrea Hull AO ҩ Thomas Hurley AO OBE ҩ Margaret Jackson AC ҩ Bevyn Jarrott ҩ Barry Jones AO ҩ Mark Jones ҩ Peter Jopling QC ҩ Dr Raymond Marginson AM ҩ Lina Marrocco OAM ҩ Jim McCluskey ҩ Elspeth McLachlan FAA ҩ George McMaster ҩ Fred Mendelsohn AO ҩ Naomi Milgrom AO ҩ Pamela Miller ҩ Harold Mitchell AC ҩ Peter Mitchell AM ҩ Brendan Murphy ҩ Baillieu Myer AC ҩ Martyn Myer AO ҩ Louise Myer ҩ A H (Buck) Myers, Jr ҩ Allan Myers AO QC ҩ Maria Myers AO ҩ Mark Nelson ҩ Hugh Niall ҩ Kerin O’Dea ҩ Simon Parker-Bowles ҩ Lady Primrose Potter AC ҩ John Poynter AO ҩ Ian Renard AM ҩ Geoffrey Ripper ҩ Eda Ritchie AM ҩ John Rose AO ҩ Thomas Schneider ҩ David Scott ҩ Richard Smallwood AO ҩ Loti Smorgon AO (dec 20/8/2013) ҩ Stephen Spargo ҩ Andrew Stripp ҩ Boris Struk ҩ Robert Trenberth AM ҩ Gad Trevaks AM ҩ Anne Ward ҩ Andrew Wardlaw ҩ Elizabeth Wardlaw ҩ Brian Watson ҩ Ingrid Winship ҩ Marelyn WintourCoghlan ҩ Meredith Woods ҩ Michael Wooldridge ҩ John Wylie AM ҩ Harrison Young

COMMERCIALISATION ҩ Mr Stephen Spargo (chair) ҩ Dr Henry De Aizpurua ҩ Professor Geoffrey Donnan AO ҩ Dr Steve Petrou ҩ Mr Andrew Stripp ҩ Dr Ross Macdonald ҩ Dr Ergad Gold ҩ Mr Wayne McMaster ҩ Mr Gary Gray

FINANCE AND INVESTMENT ҩ Mr Craig Drummond (chair) ҩ Mrs Jennifer Labourne ҩ Mr Mark Jones ҩ Professor Andrea Hull AO ҩ Professor Geoffrey Donnan ҩ Professor Graeme Jackson ҩ Professor Colin Masters ҩ Mr Gary Gray ҩ Mr Andrew Stripp ҩ Mr Peter Plecher

AUDIT ҩ Mr Mark Jones (chair) ҩ Mrs Jennifer Labourne ҩ Professor Andrea Hull AO ҩ Professor Geoffrey Donnan AO ҩ Professor Graeme Jackson ҩ Professor Colin Masters ҩ Mr Gary Gray ҩ Mr Andrew Stripp ҩ Mr Peter Plecher

NOMINATION ҩ Mr Harold Mitchell AC (chair) ҩ Mr Andrew Abercrombie ҩ Professor James Angus AO ҩ Professor Geoffrey Donnan AO ҩ Mr Rob Gerrand ҩ Professor Anne Kelso AO

EXTERNAL SCIENTIFIC ADVISORY ҩ Professor Sam Berkovic AC ҩ Professor Alastair Buchan ҩ Professor Seth Grant ҩ Professor Seong-Seng Tan ҩ Alan Connelly ҩ Amy Brodtmann ҩ Andrew Lawrence ҩ Ben Emery ҩ Colin Masters ҩ David William Howells ҩ Graeme Jackson ҩ Henry De Aizpurua ҩ Julie Bernhardt ҩ Philip Beart ҩ Richard Macdonell ҩ Robin McAllen ҩ Ross Bathgate ҩ Seong Seng Tan ҩ Steven Petrou ҩ Trevor Kilpatrick ҩ Akhter Hossain ҩ Andrea Gogos ҩ Andrew Gundlach ҩ Anthony Hannan ҩ Ashley Ian Bush ҩ Ben Gu ҩ Bevyn Jarrott ҩ Blaine Roberts ҩ Bradley Turner ҩ Brian Dean ҩ Chris Reid ҩ Clare Parish ҩ Clive May ҩ David Abbott ҩ David Finkelstein ҩ Dominique Cadihac ҩ Fernando Calamante ҩ Gawain McColl ҩ Geoffrey Donnan ҩ Helen Dewey ҩ Ingrid Eileen Scheffer ҩ Jason Howitt ҩ Jee Hyun Kim ҩ Jenny Favaloro ҩ Jhodie Rubina

Duncan ҩ Jim Wiley ҩ Joanne Britto ҩ John Drago ҩ John Wade ҩ Julie Bernhardt ҩ Karin Sitte ҩ Kevin Jeffrey Barnham

The Florey FaC ulT y & s enior P osi T ions

ҩ Lachlan Thompson ҩ Leeanne Carey ҩ Leonid Churilov ҩ Lucy Palmer ҩ Maarten Van Den Buuse ҩ Malcolm Horne ҩ Mathias Dutschmann ҩ Nathalie Braussaud ҩ Paul Anthony Adlard ҩ Rohit Ramchandra ҩ Seong-Seng Tan ҩ Suresh Sundram ҩ Timothy Douglas Aumann ҩ Tobias David Merson ҩ Wah Chin Boon

SENIOR POSITIONS ҩ Mr Trevor Clark OAM (chair) ҩ Mr Julian Clarke OAM ҩ Mr Graeme Kelly ҩ Mr Ross Oakley OAM

FOUNDATION COUNCIL ҩ Mr Stephen Spargo ҩ Professor Geoffrey Donnan ҩ Mr Ross Johnstone ҩ Mr Gary Gray

Scientific Director ҩ Professor Geoffrey Donnan AO

Florey Deputy Directors

Chief Operating Officer ҩ Dr Henry De Aizpurua ҩ Professor Graeme Jackson ҩ Professor Colin Masters ҩ Associate Professor Steve Petrou ҩ Mr Gary Gray Florey Executive ҩ Professor Alan Connelly ҩ Professor Andrew Lawrence ҩ Professor Ashley Bush ҩ Professor Brian Dean ҩ Professor Colin Masters ҩ Professor David Howells ҩ Professor Geoffrey Donnan ҩ Professor Graeme Jackson ҩ Dr Henry De Aizpurua ҩ Professor Ingrid Scheffer ҩ Associate Professor Julie Bernhardt ҩ Professor Philip Beart ҩ Professor SeongSeng Tan ҩ Associate Professor

Steve Petrou ҩ Mr Gary Gray it was with a mixture of nervousness and anticipation that the Florey embarked on its inaugural crowdfunding campaign in October 2013. Nervousness, because raising money for medical research in this manner had only been tried a handful of times around the world, and anticipation because if it worked, it would open up a new and exciting way for our scientists to fund their research, and promote it to an entirely new audience. or developers to create a new game. However, crowdfunding is gaining popularity within the scientific community as a means of raising money beyond traditional, extremely competitive granting agencies.

We used Pozible.com the biggest crowdfunding website in Australia and the third biggest, worldwide.

iT is Pozi B le

Seven groups were selected to take part in the campaign, covering disease areas such as stroke, Parkinson’s disease, schizophrenia, addiction and autism. Of these groups, four successfully reached their target, raising a combined total of over $70,000 in new research funding. These funds will contribute to new lab equipment, a salary for a new staff member, a student stipend and reagents to create new research tools.

The campaign also raised the public profile of the Florey, generating media interest across national newspapers, radio and television.

One of the successful projects, “DNA: We are what we eat!”, was run by Dr Wah Chin Boon and her masters student, Kris Vacy, from the Neurodegeneration division. By raising over $15,000, they’ll be able to investigate human DNA changes in response to environmental influences, in an experiment informed by their NHMRC-funded preclinical work in mice.

That work has shown that if certain compounds are present in food, genes thought to be important in normal brain development are ‘turned off’ leading to an increased risk of developing autism.

Without the money generated from this campaign, we wouldn’t be able to show proof-of-principle in humans at all.

Social media was also a key driver of the campaign’s success, with thousands of hits on Twitter, Facebook and Youtube, exposing our cutting edge science to a new, younger demographic.

Crowdfunding might be an unfamiliar concept to some. The idea is to use the power of the “crowd” to raise funds for a discrete research project by asking hundreds or thousands of backers to each contribute a small amount, thereby reaching your target. If you fail to reach the target in the allotted time, you receive no funds (called the “all-or-none” model).

Until recently, crowdfunding has been used to fund “creative” projects such as filming a documentary, recording an album or shooting a music video, providing travel funds for artists, musicians or writers to attend festivals

The $15,000 will be used to run a small pilot study to collect cheek cells from the saliva of autistic and unaffected people, to test if the same mechanism is present in humans. In addition, they will develop a survey to look at whether parents of autistic individuals were heavily exposed to these compounds around the time of conception and while their children were in utero, which will inform public health policy in Australia.

“If successful, this study will form the basis of another NHMRC grant application,” says Wah Chin. “Without the money generated from this campaign, we wouldn’t be able to show proof-of-principle in humans at all. It was also pleasantly surprising to see how much public interest our project generated, and how widespread. We had supporters from as far way as Canada, the US, the Czech Republic, Singapore and even Mongolia! Who do I know in Mongolia?!” ҩ Chris Abbott AM ҩ David & Slavka

Abraham ҩ Marjorie Anne Ada ҩ Christine Adams ҩ Peter Adams ҩ Joan Adler ҩ Stephanie Aeuckens ҩ Cameron Afrasiabi ҩ Yvionne Ahmet ҩ Michael Aitken ҩ R M & S P Allan ҩ Allbeau Pty Ltd ҩ Charles K Allen AO ҩ Frances Allen ҩ R G & L N Allen ҩ Rod & Joan Alsop ҩ Walter Ames ҩ Katherene Anderson ҩ Keith Anderson ҩ R Andre ҩ Ronald Angley ҩ Judith Anketell ҩ ANZ Trustees Limited ҩ A M Arbuckle ҩ Marilyn Armstrong ҩ Barbara Ashton ҩ Robert Atkins ҩ Tony Atkinson ҩ Robert Audsley ҩ Patrick Aughton ҩ Australian Communities Foundation ҩ Philip & Margaret A’Vard ҩ Harjit Bagga ҩ W J Bailey AO ҩ Gordon Baird ҩ Peter Baird ҩ Thelma Baker ҩ David N Balcombe ҩ Raechel & Danny Ballinger ҩ William E Bamford ҩ David Barkley ҩ Philip Barlow ҩ E Jane Barrett ҩ Paul Bartlett ҩ Graeme Bate ҩ John & Lorraine Bates ҩ Elizabeth Batt ҩ Ron & Claire Batten ҩ Vera Baudinette

Our Donors

We appreciate the generosity of our donors and would like to especially thank those who have given $100 or more during 2013 ҩ William R Baxter ҩ Margaret Bayliss ҩ Peter & Sharon Beaconsfield ҩ Richard & Mirion Bearman ҩ Josephine Beatson ҩ Sally Beavis ҩ Carmel Behan ҩ Annette Bell ҩ Bell Charitable Fund ҩ Doreen Bell ҩ Alan Benger ҩ Sandra R Benjamin OAM ҩ David Bennett ҩ John & Connie Bennett ҩ Valerie F Benson ҩ Colin & Barb Benson ҩ Katherine Berriman ҩ Rasa Bertrand ҩ Berwick Opportunity Shop Incorporated ҩ Besen Family Foundation ҩ Bethlehem Griffiths Research Foundation ҩ BHP Billiton Matched Giving Program ҩ William Birch AM ҩ Ian Birchall ҩ Ian L Birchall ҩ Katie Bird ҩ R D G & M J Birrell ҩ Frederick K Bishop ҩ Debbie Black ҩ Evangelo Bladeni ҩ G R Blair ҩ John Blanch ҩ Michael Blaney ҩ Mardi Blatchford ҩ Neal Blewett AC ҩ Sidney & Felicity Bloch ҩ Blue Illusion ҩ Lola J Bosisto ҩ Don Boulter ҩ Carolynne Bourne AM & Michael Bourne ҩ John Bowen ҩ Ken & Marlene Bowes ҩ Graeme Bowker ҩ Christien Boyle ҩ BP Employee Matching Fund ҩ Robert H Braby ҩ Brain Foundation ҩ Brian J Brand ҩ B M Brennan ҩ Mavis Brennan ҩ William & Marie Brennan ҩ Breville ҩ Marietta Brinkley ҩ Andrew Brock ҩ Janette Broom ҩ Dennis J Bryant ҩ Jim A Buchanan ҩ Sally Bufe ҩ M J Bugg ҩ Margaret Bullen ҩ Bupa Health Foundation ҩ Lynne Burgess ҩ Ian Burgher ҩ Margaret Burke ҩ Gabriel Burman ҩ June Burrell ҩ Norman & Kath Bury ҩ Peter Butler ҩ Elizabeth Butt ҩ Ronald Butters ҩ R I Byers ҩ Jarrod Byham ҩ Madeline Byrne ҩ Terry Salmon ҩ CAF Community Fund ҩ Yvonne Cainer ҩ Tom Callander ҩ Libby & Nick Callinan ҩ Rosemary Callow ҩ Virginia Cameron ҩ June Cameron ҩ Christine Campbell ҩ Ross Campbell ҩ Deborah Candy ҩ Suzi Carp ҩ C M Carrigan ҩ Deirdre Carter ҩ Don Cashmere ҩ M G Cavanagh ҩ Ce Soir Lingerie ҩ Suzanne Cecil ҩ Enrico Cementon ҩ Diana Cerini ҩ George Chabvonga ҩ Jennifer Chambers ҩ Jill Chapman ҩ Stephen P Charles

Our Donors

We appreciate the generosity of our donors and would like to especially thank those who have given $100 or more during 2013 ҩ Sylvia A Charlton ҩ I G Chenoweth ҩ Diana & Edward Cherry ҩ Ahnya Chuah ҩ Penelope Clark ҩ Faye Clarke ҩ Robert J Clarke ҩ Heather Clay ҩ Stuart Cleland ҩ J L & E S Cleland ҩ Barbara Clifford ҩ Stephen J Clifton ҩ Arthur C Close ҩ Christien Clough ҩ Susan Coates ҩ Dale Cole ҩ Jan & Michael Cody ҩ Catherine J Coghlan ҩ Sally Cohen ҩ Deirdre Collier ҩ John & Chris Collingwood ҩ Barbara Coltman ҩ Frank & Dorothy Colwell ҩ Community Enterprise Foundation ҩ Rohan Connolly ҩ Continence Foundation of Australia ҩ B B & S H Cooling ҩ Heather Coombes ҩ David Copolov ҩ Janet Corden ҩ Kevin J Cosgrave ҩ John Coughlan ҩ Peter Coughlan ҩ Helen Cowan ҩ Mary Crean ҩ Donalda Crofts ҩ Ken Cuming ҩ CWA Victoria Gormandale Branch ҩ Pam Dalrymple ҩ Philip E Darby ҩ L Gordon Darling AC CMG & Marilyn A Gordon ҩ Barbara Darvall ҩ Arthur & Anne Davey ҩ Geoffrey Davey ҩ Joan Davidson ҩ Brian Davis ҩ Ernest F Dawes OBE

FTS ҩ Helen Dawes ҩ Ann De Paul ҩ C M Deeley ҩ Abaran Deep ҩ S Deeves ҩ Eril Deighton ҩ Matthew Delasey ҩ Mark Dick ҩ Douglas & Marion Dickinson ҩ Jacqueline Digby ҩ W Dix ҩ J & D Dixon ҩ Dixson Trust Pty Ltd ҩ Billie Donaldson ҩ John Donegan ҩ Kerrie Donker ҩ Sarah Donnan ҩ Patricia Donovan ҩ Carl & Wendy Dowd ҩ David Dowdle ҩ Michael Dowling ҩ Rose Downer ҩ K & M Doyle ҩ Dr Alan Wade Alzheimers Research Fund ҩ Margaret Drake ҩ Alison Driver ҩ Craig M Drummond ҩ Ian Drummond ҩ Mary Duckworth ҩ Jan Dunbar ҩ R M Duncan ҩ Andrew R Dyer ҩ Margaret Dyson ҩ Dysons Group of Companies ҩ East Family Trust ҩ Geoffrey & Pauline Eastmure ҩ Ethel Edwards ҩ Wilma Edwards ҩ Marie Einoder ҩ Elcome Leslie Da ҩ Marie Ellis ҩ Peg Elmore ҩ Jo Elvins ҩ June Entink ҩ Andrew Erikson ҩ Estate of the late Pauline Mary Johnston ҩ Estate of the late Mary Eva Kentish ҩ Estate of the late Marjorie Mary Jackson ҩ Estate of the late Anne D Carroll ҩ Desmond Fanning ҩ Evelyn Fawcett ҩ FEI ҩ David Feldman ҩ Julian Feller ҩ B J & P M Ferguson ҩ Rita Ferguson ҩ Tony Fisher ҩ Jeanne Fletcher ҩ Roger B Flynn ҩ Anne Foote ҩ Arthur & Rita Ford ҩ Barb & Frank Ford ҩ Foresters Friendly Society ҩ Isolde Forstmanis ҩ Cathy Foster ҩ Ann Fraser ҩ Lucy Freestone ҩ Shirley Fricke ҩ Ronald Friedman ҩ Norman Frost ҩ A K Fryday ҩ Gemma Furtado ҩ Derek Fyfield ҩ J E & P Gander ҩ Dorothy M Gannon ҩ Neilma Gantner ҩ Frances Rae Gardiner ҩ David Gawler ҩ Sheila Gawler ҩ Rosemary Geer ҩ Geoff & Helen Handbury Foundation ҩ Lesley Gerrish ҩ C Norman Geschke OBE ҩ Roshan Ghadamian ҩ Giant Steps Sydney ҩ Keith Gibbs ҩ Tess Gibbs ҩ E & A Gifford ҩ Peter Gilbertson ҩ Brian & Jan Gill ҩ Shirley Gionfriddo ҩ Clare GleesonMcGuire ҩ William Gobbart ҩ Leon & Myriam Goldberg ҩ Alan Goldberg AO QC ҩ Andrea Goldsmith ҩ Dominic Goodwin ҩ R N Gotch ҩ Louise Gourlay OAM ҩ Anna Gouttman ҩ David & Debbie Grace ҩ Susan V Grant ҩ Gail Greatorex ҩ Robert G Grierson ҩ Lesley Griffin ҩ Edwin Griffith ҩ Betty Griffiths ҩ Michael & Evelyn Gross ҩ Helen K Groves AO ҩ Joy B Guerin ҩ James Guest AM OBE ҩ John Guthrie ҩ H & K Johnston Family Foundation ҩ H W I Electrical Ltd ҩ Chris Haines ҩ John Hales ҩ Elisabeth Anne Hall ҩ Ronda Hall ҩ Kristine Hambly ҩ Olive Hamilton ҩ Gail Hammond ҩ Sylvia Hammond ҩ James A Hancock OBE ҩ David Hannaford ҩ Kate Hannan ҩ Hartley R Hansen ҩ Marjorie Harbour ҩ Roy Hardcastle ҩ V E Harding ҩ Joan M Harman ҩ Yvonne Harper ҩ Richard Harrison ҩ T Hart ҩ C Haslam ҩ Kathleen Hatch ҩ Annette Hayes ҩ Brian Head ҩ Peta Heffernan ҩ Elizabeth M Heinze ҩ Gordon Hellsten ҩ Wilma J Herschell ҩ Margaret Heselev ҩ Highett RSL Women’s Auxiliary ҩ Alistair Hillier ҩ Margaret Hilton ҩ W E Hirst ҩ Robert & Tina Hocking ҩ John & Bev Hodgkisson ҩ Beryl Hogben ҩ Russell Hogg ҩ Judith Holden ҩ Julian Hopper ҩ Harry Hornstein ҩ Peter Howard ҩ Bryan Hoy ҩ Heather Hughes ҩ Lila Hughes ҩ Keith R Hutchison ҩ Peter Huveneers ҩ Joan E Ikin ҩ Illabarook Pty Ltd ҩ Rowan V Ingpen ҩ Interpath Services

Pty Ltd ҩ Ionian Club (82)

Melbourne Inc ҩ G Jackman ҩ Jean Jackson ҩ Lindsay Jackson ҩ David Jacobson ҩ G Jacobson ҩ Brian D James ҩ Norman James ҩ Elcahnan H Januszewicz ҩ Barbara E Jenkins ҩ Graeme & Rosemary Jenkins ҩ Nola Jennings ҩ Campbell & Caroline Johnston ҩ Peter Johnston ҩ Elizabeth Judd ҩ Leah Kaplan ҩ Karingal Bowling Club ҩ H Karsen ҩ D & M Kaufmann ҩ Sue Keable ҩ Alison Kearney ҩ Maree Keating ҩ Gerard Keeghan ҩ Graeme Kelly ҩ Peter Kelly ҩ Raye Kelly ҩ Anne Kelso AO ҩ Jennifer Kelso ҩ Max & Wilma Kemp ҩ Stephen Kenmar ҩ Margaret Keogh ҩ Bryan & June KeonCohen ҩ Janice D Kesterton ҩ Michael Kibalenko ҩ Joseph Kiers ҩ Pamela Killer ҩ Leslie Kilmartin ҩ Robyn Kingston ҩ Terry & Janet Kinsella ҩ A J Kirkham AM ҩ Paul Kirton ҩ Val Knaggs ҩ Peggy Knight ҩ Rodney & Beverley Knight ҩ Pam Knott ҩ P Kolliner OAM ҩ Helen Kosky ҩ Frances La Fontaine ҩ Joy Lambert ҩ John Landy AC CVO

MBE & Lynne Landy ҩ Anne Lang ҩ Gina Langlands ҩ Mildred Lapthorne ҩ John & Dymphna

Laurie ҩ George Lawrence ҩ Judith Lawrence ҩ Joseph Lederman ҩ James Lees ҩ Peter Lemon ҩ Alison Leslie ҩ Lewis Lester ҩ Paul & Jill Lethlean ҩ Jackson Leung & Lucia

Fong ҩ Patricia Levy ҩ Penny Lewisohn ҩ Ollie & Chris Liedtke ҩ Elsa Lindsay ҩ Ambrose Linke ҩ Lions Club of Somerville ҩ John Lippmann OAM ҩ Norma Lithgow ҩ Brian Little ҩ Terence Little ҩ Algirdas E Liubinas ҩ Douglas Livermore ҩ Loke Kah Seong ҩ Elizabeth Loorham ҩ Elisabeth N Lord ҩ Anna Louey ҩ Naomi Loughhead ҩ Diana M Lowe ҩ Pearl Lubansky ҩ Judith Lunt ҩ Kevin Luscombe AM ҩ Frances Luxon ҩ Doreen Lydeamore ҩ Irene Lynch ҩ Michael Macgeorge ҩ Christine MacGill ҩ Rosemary B S Macindoe ҩ Macquarie Group Foundation ҩ R & M Maeder ҩ Lescil G Maidment ҩ Don Maloney ҩ Elaine Mann ҩ Joan Mann ҩ Creagh Manning ҩ Maple-Brown Abbott ҩ Bridget Mar ҩ Ian J Marks ҩ Brian & Anne Marshall ҩ Marjory-Dore Martin ҩ Ruth Martin ҩ Heather Mason ҩ Janet Mather ҩ Jean Matthews ҩ Arthur & Christine Mavrodoglos ҩ Christopher Maxwell ҩ M McAllister ҩ Darryl McAndrew ҩ Peter McArdle ҩ R A McCallum ҩ Ian W McCay ҩ P T McColl ҩ Andrew McComas ҩ Karen McComiskey ҩ V McCormack ҩ Denys McCullough ҩ David McDonald ҩ John McDonnell ҩ J & B McEnroe ҩ Marion McEwin ҩ Emmeline McFadyen ҩ Joan McGilvray ҩ Katherine McGloin ҩ Joan McHardy ҩ A J McIntosh ҩ Noeleen McKenry ҩ Bruce McKenzie ҩ Colin McLaren ҩ Ken & Pat McLaren ҩ Raymond J McLean ҩ Kathryn McLeod ҩ Graham McMahon ҩ Alexander J McMillan ҩ Janice Medway ҩ R J & W D Meggs ҩ Lawrence Melgaard ҩ Graham A Menzies ҩ Merrilyn Murnane Discretionary Account ҩ Hans & Monica Meyer ҩ John & Marilyn Meyer ҩ John Michaux ҩ Judith Middlemass ҩ Ian & Heather Mills ҩ Roslynne Milne ҩ Mir Bros Group of Companies ҩ Heather J Mitchell ҩ R Mittlema ҩ MND and Me Foundation ҩ Margaret Moller ҩ Gillian Montgomery ҩ Stan Moore ҩ Carole Moran ҩ G A & C R Morgan ҩ J Morgan ҩ Geoffrey Morley ҩ Patricia Morrice ҩ Arthur Morton ҩ Richard Moshinsky ҩ Motor Neuron Disease Association of Victoria ҩ N Beverley Mower ҩ Hazel Moyes ҩ Jennifer Mullen ҩ Munday Des & Son ҩ Bruce Munro ҩ Richard A Munt ҩ J M Muntz ҩ Kitty Muntz ҩ Anna Murphy ҩ Bruce Murrie ҩ David Murrie ҩ My Cause Gift Fund

Our Donors

We appreciate the generosity of our donors and would like to especially thank those who have given $100 or more during 2013 ҩ Nancy & Vic Allen Stroke Prevention Fund ҩ Dennis & Fairlie Nassau ҩ J & S Nathar ҩ Nell & Hermon Slade Trust ҩ Jennifer Newton ҩ Helen Ng ҩ Alison Nghiem ҩ Anthony Nicholas ҩ John & June NixonSmith ҩ Robert Nossbaum ҩ Aileen Oberegger ҩ Doris Enid O’Brien ҩ Doreen O’Brien ҩ Margaret O’Brien ҩ R M O’Collins ҩ Sue Ohl ҩ Dianne Olston ҩ Kerry O’Meara ҩ One in five Association Inc ҩ Sue O’Neill ҩ K Oram ҩ Mona Osborne ҩ Damien O’Shea ҩ Judith A Overbeek ҩ Robin Palmer ҩ Justine Paragreen ҩ Ashley J Parker ҩ Scott Parker ҩ Trish Parker ҩ Parkinson’s Victoria Inc ҩ Nick Pastalatzis ҩ Jeremy Paterson ҩ D Patisteas OAM ҩ Patsy Patten ҩ Angelos & Janet Pavlakis ҩ Deb Peart ҩ Nigel Peck AM ҩ Elizabeth Pender ҩ Penfold Motors ҩ Perptual Trustees ҩ Mary Phiddian ҩ Daniella Phillips ҩ Ian R Phillips ҩ Michelle Picker ҩ Pierce Armstrong Foundation ҩ Dorothy Pill ҩ David Pincus ҩ Donald M Pinkerton ҩ Geni Pirrie ҩ Pitcher Partners ҩ R G Pitcher AM ҩ Vivienne Player ҩ Roland Pless ҩ Margaret Poh Kam Chan ҩ K & L Porter ҩ Renate Porter ҩ Jean Potter ҩ Primrose C Potter AC ҩ Allan Powell ҩ Norah Powell ҩ Ed Prendergast ҩ Joan Preston ҩ Elizabeth Price ҩ Rod & Sue Price ҩ Suzanne Pullen ҩ Kalli Pulos ҩ Anthony & Helen Pyman ҩ Judith Raleigh ҩ Alan Ramsay ҩ Rebecca L Cooper Medical Research Founda ҩ Ann Reid ҩ Jenny Reid ҩ Simon Reid ҩ Ralph & Ruth Renard ҩ Staniforth Ricketson ҩ Jo Ridgeway ҩ Maureen Rigby ҩ L Rimington ҩ Joyce E Risstrom ҩ Ritchies Expense Company ҩ Rachel Robbins ҩ Ann Robertson ҩ RobMeree Foundation ҩ Margaret Robson ҩ David W Rogers ҩ John Rogers ҩ Kitty Rohan ҩ Mirella Rossi ҩ Rotary Club of Chirnside Park ҩ Rotary Club of Geelong East ҩ Rotary MS Awareness Committee ҩ Gwyneth Rothols ҩ Cynthia & John Rowe ҩ Marie Rundell ҩ Joan Russell ҩ Jennifer Ruthen ҩ Ruyton Girls School ҩ Ron Sacks-Davis ҩ Dominic Sadsad ҩ Donald N Sanders AO ҩ Joyce Sanders ҩ Anne Sanderson ҩ Lauren Sanford ҩ Norman Sargeant ҩ Paul Saunders ҩ Joyce Savage ҩ Matthew Savage ҩ Jim Sawyer ҩ Say Family Foundation ҩ Walter Scharley ҩ Heather Scott ҩ Alan Searl ҩ Stefan Segolin ҩ Sessions Funeral Services ҩ Ian Seymour ҩ ShareGift Australia ҩ Margaret Sharp ҩ John & Pamela Sharwood ҩ David Shaw ҩ Keith & Frances Shaw ҩ Sue Sheedy ҩ Andrew Shenton ҩ Sid & Fiona Myer Family Foundation ҩ Jantina E SillitoeGoossen ҩ Mark Simcocks ҩ George & Bevley Simonsen ҩ Robert & Elisabeth Sinclair ҩ Justine Sloane-Lees ҩ Isabel M Sloman ҩ Peg Smart ҩ Betty M Smith ҩ Bob Smith ҩ Carol A Smith ҩ Keith S Smith ҩ Nick Smith ҩ Nola Smith ҩ Valerie E Smith ҩ Mark Smithies ҩ Graham Snell ҩ Sylvia Solinski ҩ Liz Somerville ҩ Joy Sorel ҩ Southern Peninsula Masters Athletics Venue ҩ Pauline Speedy ҩ Alex Spremic ҩ Barrie Squires ҩ Jane Standish ҩ Tony & Barbara Standish ҩ Maureen Stavely ҩ A W Stephens ҩ P Stephenson ҩ Jennifer Stevens ҩ Margaret Stevens ҩ Gary Stiliano ҩ Betty Stinson ҩ Robert Stinson ҩ Susie Stock ҩ W E Stone ҩ Caroline Storm ҩ Stosius & Staff Constructions Pty Ltd ҩ Fay Strachan ҩ Patricia Strachan ҩ Richard Stradwick ҩ Takako M Subocz ҩ Valerie Summers ҩ Kylie Sutherland ҩ Rene Sutton ҩ Elizabeth Joan Swain ҩ Peter Swan OAM ҩ Robbie Swanson ҩ Sylvia and Charles Viertel Charitable Foundation ҩ Gregory & Wendy Taggart ҩ Sally Taleb ҩ Angela Taranto ҩ John & Elaine Targett ҩ Anne Taylor ҩ Bernadette Taylor ҩ John Taylor ҩ Michael Taylor ҩ Margaret Taylor ҩ Robin Taylor ҩ Wendy Taylor ҩ B & P Teague ҩ Felicity Teague ҩ Kathryn Thaniel ҩ The Abercrombie Family Foundation ҩ The CASS Foundation Ltd ҩ The Eirene Lucas Foundation ҩ The Finkel Foundation ҩ The G W Vowell Foundation Ltd ҩ The Greatorex Foundation Pty Ltd ҩ The Grocer ҩ The Habboush Family ҩ The Ian Potter Foundation ҩ The Ideal Consultancy ҩ The Isabel & John Gilbertson Charitable ҩ The Jack Brockhoff Foundation ҩ The Landman Foundation ҩ The Leo & Mina Fink Fund ҩ The Lochtenberg Foundation ҩ The Marchris Family Charitable Gift ҩ The M.A.S.T Foundation

Our Donors

We appreciate the generosity of our donors and would like to especially thank those who have given $100 or more during 2013 ҩ The Miller Foundation ҩ The Myer Foundation ҩ The Next Step Recruitment Company

Pty Ltd ҩ The Pratt Foundation ҩ The Slome-Topol Family Charitable Trust ҩ The Stuart Leslie Foundation ҩ The William Angliss (Vic) Charitable Fund ҩ The Yulgilbar Foundation ҩ Jean Thomas ҩ Val Thomas ҩ William D Thorn ҩ Robert C Thrower ҩ J G Thrum ҩ David Thwaites ҩ Andrew Tinney ҩ Marjorie Todd ҩ Diana Tolhurst ҩ V Tolliday ҩ Jean Tom ҩ Lynette Torrens ҩ Norma Torriero ҩ Evelyn Townsend ҩ David Tregear ҩ Brian Tress ҩ Gad Trevaks AM ҩ E Trevena ҩ Trust Company Ltd ҩ Eugenia Tsaclidis ҩ Joan Tullo ҩ Bruce Turnbull ҩ Maureen Turner ҩ Patricia Turner ҩ Peggy Tweedley ҩ Margaret J Ullin ҩ G L & J H Upston ҩ Eleanor U’Ren ҩ Anne Van Erp ҩ Luke Vaughan ҩ David Vernon ҩ Hans Von Strokirch ҩ Paul R Voumard ҩ J R Vroland ҩ Marilyn Wagen ҩ Elizabeth Walker ҩ Jen Walker ҩ Richard Wall ҩ Stan Wallis AC ҩ Ken Walters ҩ R N Walters ҩ Peter Ward ҩ Ralph & Barbara Ward-Ambler ҩ Warringal Financial Services Pty Ltd ҩ Kim Waters ҩ A D Watson ҩ Barbara Watson ҩ Donald Watson ҩ Jean Watson ҩ Margaret E Watson ҩ Colin & Julie Watt ҩ Gwen Webb OAM ҩ Philip Weickhardt ҩ Western Union Foundation ҩ John Wheatley ҩ Trevor White ҩ Lesley Whitehead

su PP or T ing resear C h

ҩ Alex & Karl Waddell – River’s Gift ҩ The Age Run Melbourne 2013 ҩ Matt Harry – Channel Swim ҩ Faith in Neuroscience – Crowdfunding by Faith Lamont ҩ Name the Virus – Crowdfunding by David Hawkes ҩ DNA and Autism, We are what we eat

– Crowdfunding by Wah Chin Boon ҩ Robyn Whiteley ҩ Harold & Joan Whitfield ҩ Janet Whiting ҩ Kaaren Whyte ҩ James S Wiley ҩ Karin Wiley ҩ John & Robyn Wilkins ҩ Paul A Willee QC ҩ Keith Williams ҩ Lyn Williams AM ҩ Peter R Williams ҩ Vera Williamson ҩ Andrew Wills ҩ Elizabeth Wilson ҩ Margaret Wilson ҩ Marie Wilson ҩ Robin Wilson ҩ William P Wilson ҩ Claire Withers ҩ David & Isabel Wluka ҩ Alex Wood ҩ Sandy Young ҩ Lady June Zeidler ҩ WHYBIN/TBWA ҩ Linklaters ҩ Dr Greg Taggart ҩ Drug Free Brain Treatments –Crowdfunding by Tim Aumann ҩ Beryl Nielson – Raising funds for Epilepsy Research ҩ Run for Matthew Patterson ҩ Rob’s Fundraising for Parkinson’s Disease Research ҩ Cycling Fundraiser for AVERT ҩ One in Five Long Lunch

We gratefully acknowledge the tireless efforts of people in the community who raise funds to support our research, and thank the donors who have supported them i ҩ One in Five Extreme Challenges ҩ One In Five Bolt Blowers Surf Event ҩ Tim Blashki – Beyond Words Art Exhibition ҩ Enid Telford & Sue O’Neill – hand made cards for sale at markets

or T ers

ҩ Prof Malcolm Horne ҩ Ryan Wavish ҩ John Doyle ҩ Sally Watt ҩ Brook Angove ҩ Prof Fred Mendelsohn AO ҩ Kate Richards