University of Tennessee, Health Science Center J. R. Hyde Chair of Excellence in Rehabilitation Engineering Status of the Chair of Excellence William M. Mihalko, MD, PhD serves as the J. R. Hyde Chair of Excellence in Rehabilitation Engineering since January 2012. Dr. Mihalko’s research focuses on identifying the biomechanical, kinetic/kinematic, biologic, and clinical related issues pertaining to failures and patient reported outcomes in total joint arthroplasty.
Impact of Chair of Excellence on UTHSC, College, and Programs Active Grants and Other Sources of Funding: 4 • R078500203 Campbell Clinic Foundation Contract: Kinematic and kinetic differences of total knee arthroplasty designs and surgical alignment, $139,848. • R073290158 Drexel University Food and Drug Administration (FDA) grant subcontract: Local and systemic effects of metal ions in total knee arthroplasty, $162,782. Publications (2023-24): 7 published; 1 accepted for publication; 5 under review. Presentations (2023-24): 5 International, 8 national Faculty Mentoring or Other Active Collaborations: • New collaborations continue with Clemson University, Drexel University and Cleveland Clinic and awarded a new Food and Drug Administration grant starting September 2023 looking into biologic and local inflammatory effects on metal alloys used in joint replacement. • New collaborations continue with Drs. Derefinko and Johnson in Preventive Medicine on topical treatment of knee osteoarthritis pain and R01 application submitted this summer cycle to NIAMS 6/2024. • Dr. Phyllis Richey Preventive Medicine on Reaching significant weight loss after Total Knee Arthroplasty in Obese Patients. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) R01 scored 20% and will resubmit for fall cycle 10/24. • Dr. Throckmorton and Dr. Brolin collaboration on Kinematics/Kinetics and muscle activation patterns in reverse total shoulder arthroplasty. Preliminary work has received the Charles Neer Award from the American Shoulder and Elbow Surgeons Foundation (https://www.asesassn.org/about-ases/charles-s-neer-award/) and an R21 will be resubmitted this fall 10/24. Other Evidence of Impact on the Institution: • Program chair for the Joint Graduate Program in Biomedical Engineering with one graduated MS student 2022-23, two current supported MS students this fall 2023, and one supported PhD student in Rehabilitation Science Program. • Received AAHKS Clinical Research Award at the annual meeting 11/23: The AAHKS Clinical Research Award: Extended Postoperative Oral Tranexamic Acid in Total Knee Arthroplasty: A Randomized Controlled Pilot Study. Kirwan MJ, Diltz ZR, Dixon DT, Rivera-Peraza CA, Gammage CJ, Mihalko WM, Harkess JW, Guyton JL, Crockarell JR, Ford MC. J Arthroplasty. 2024 Feb 29: S0883-5403(24)00193-1. doi: 10.1016/j.arth.2024.02.073. Online ahead of print. • Have updated and modernized the Motion Analysis Laboratory with Dr. Dale Barry Chair of Physical Therapy. • Currently on the Board of the Hip Society and serve as President for the International Society for Technology in Arthroplasty. I also run the AAHKS Research course for 2024 and serve as the co-editor for Orthopedic Knowledge Update Hip and Knee for the American Academy of Orthopedic Surgeons 2024. Tennessee Higher Education Commission 2023-24 Chairs of Excellence Annual Report Page 93