Gram-positive Organisms (6) Listeriosis Listeria monocytogenes Gram ⊕, facultative intracellular rod (bacillus) acquired by ingestion of unpasteurized dairy products & cold deli meats, via transplacental transmission, or by vaginal transmission during birth Forms “rocket tails” (red) via actin polymerization that allow intracellular movement and cell-to- cell spread across cell membranes, thereby avoiding antibody Can cause amnionitis, septicemia, and spontaneous abortion in pregnant women, granulomatosis infantiseptica, neonatal meningitis, meningitis in elderly and immunocompromised patients; mild, self-limited gastroenteritis in healthy individuals Treatment: ampicillin in infants, immunocompromised and elderly as empirical treatment Marc Imhotep Cray, M.D.of meningitis