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Heartcore Capital - AI & Productivity Report 2023

Page 29

Konstantine Buhler

Nathan Benaich

Partner at

General Partner at

Chosen research paper:

Chosen research paper:

Released in Apr 2021

Released in January 2023

Generative Agents: Interactive Simulacra of Human Behavior

Large Language Models Generate Functional Protein Sequences Across Diverse Families

Stanford University - Joon Sung Park, Joseph C. O'Brien, Carrie J. Cai, Meredith Ringel Morris, Percy Liang, Michael S. Bernstein

Profluent, Salesforce - Ali Madani, Ben Krause, Eric Greene, Subu Subramanian, Benjamin Mohr, James Holton, Jose Luis Olmos Jr, Caiming Xiong, et al.

Why it’s important:

Why it’s important:

"In this paper, the team out of Stanford places several generative agents in a shared digital world somewhat similar to the game Sims. These agents, built on LLMs, interact with each other. The interactions are surprisingly realistic, including a coordinated Valentine's day party. If the AI revolution is a continuation of the personal computer revolution, as in a revolution of computation, prediction, and work, then this type of multi-agent interaction is reminiscent of the early days of PC-networking, which eventually led to the Internet."

"Madani et al. demonstrate how a language model architecture originally designed for code can be adapted to learn the language of proteins. Through large-scale training, they use a protein language model (ProGen) to create artificial protein sequences that encode functionality that is equivalent to or better to naturally occurring proteins. This means we can generate proteins (drugs or otherwise) with desired functions in a far more systematic way than ever before."

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