DEPARTMENTALRESEARCH
Inside the CRU: Innovation at its Core
Role of the Splanchnic Vascular Compartment in Heart Failure with Preserved Ejection Fraction
Pacira BioSciences, Inc. Pacira 402-C-124
Zynex Monitoring Solutions ZMS-2023
Department of Defense: $576,446 NIRSense: Argus Oximetry System
Norbert Health
Norbert Health (NCP-0003) Cyban Brain Pulse Oximeter - Bsp02
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Biobank of >100K Human Specimens from Study Participants for Translational Research
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Anesthesiology CRU
Career Development of Research Staff for High Quality Retention & Engagement
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Haisco-USA Pharmaceuticals, Inc. Covance HSK3486-305
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Ashraf Habib
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HemoSonics, LLC
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Terrence Allen
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WOMEN’S ANESTHESIOLOGY
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Doris Duke Charitable Foundation, Inc.: $164,596
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David MacLeod
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REGIONAL ANESTHESIOLOGY
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Biohaven BHV-3000-317 TMD Study
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Biohaven Pharmaceuticals
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Aurelio Alonso
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PAIN MEDICINE
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Low Neurophysiologic Resistance to Anesthetics as a Marker of Preclinical/Prodromal Alzheimer’s Disease and Neurovascular Pathology, Delirium Risk and Inattention
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National Institute on Aging: $784,183
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APOE4 Dependent Regulation of CSF Complement Pathway Activation in the Development of Alzheimer’s Disease
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National Institute on Aging: $810,435
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Miles Berger
independent research programs, the CRU, directed by Dr. Kamrouz Ghadimi, stands out for a departmental its unique initiatives. One such section that further innovation is the development organizes clinical of a neurocognitive testing core, and translational research missions garnering national acclaim for its in all areas of anesthesiology, critical involvement in federally-funded care medicine, pain medicine, and investigations through the rigor and perioperative research at Duke reproducibility by which testing is University Medical Center, its performed. In addition, the CRU affiliated local sites, and serves as a has invested in the growth and coordinating center or participating development of personnel through site for multisite research. For more the use of a Clinical Research Career than two decades, the CRU has Development Ladder. In partnership grown to include more than 40 core with the Duke University School personnel who currently support of Medicine’s Master of Biomedical more than 80 prospective trials and Sciences (MBS) program, the observational studies each year. CRU has recruited several MBS Recently, the CRU has supported graduates who have started their a growing NIH-funded clinical career in clinical research as entryresearch portfolio from departmental level specialists and then often faculty that approached 20 grants in promoted to the level of clinical the past year. research coordinator. In 2023, Distinguishing its capabilities, the unit introduced a monthly the CRU excels in biospecimen seminar, referred to as the Clinical repository development with Research Initiatives, Staff, Planning, translational methods for and Education (CRISP-E) series, biospecimen acquisition, which offers a structured in-person protocolized sample processing in platform for CRU staff to engage in its laboratory, sample provenance mutual learning, benefit from faculty and governance, and freezer storage expertise, and exchange knowledge. and maintenance. The CRU In January, the CRU introduced the biorepository houses nine -80 Celsius Team Lead Committee to provide a freezers with more than 100,000 structured team-based collaboration human biospecimens that may between its lead coordinators be utilized for follow-on and leadership team to provide translational investigations learning opportunities for and collaborations. research operations and Sustained Beyond supporting to enhance quality Excellence in faculty investigators improvement within Research Operations in their ability the multiple for > 20 years to cultivate domains of and sustain the CRU. Duke The Clinical Research Unit (CRU) is
Patient-Centered Approach
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