1 minute read
Dr. Hu & Simmer Lab
from Research Day 2023
by M Dentistry
Next Article
Tian Liang
Description:
Degenerating ameloblasts in an Acp4 mutant mouse. Enamelin, actin filament, and nuclei are denoted in red, green, and blue, respectively.
Dr. Hu & Simmer Lab
Charlie Smith
Description:
Ameloblasts of Slc13a5R337*/R337* mice, in the early stage of enamel formation, contain a large number of secondary lysosomes (orange) likely due to a significant amount of proteins being redirected for degradation. The Slc13a5R337* mouse model was generated using CRISPRcas9 gene-targeting to introduce a premature stop codon at Slc13a5R337 homologous to human mutation SLC13A5R333* that resulted in developmental and epileptic encephalopathy 25 (DEE25) and amelogenesis imperfecta (MIM#615915).
Dr. Kuroda lab
Kyoungjin Seo, Kenichi Kuroda
Description:
“Matrix formed by bacteria sugar uptake on the agar plate” EPS matrix driven mechanically popped up S.mutans macro colony after growing on the broth agar incombination with sucrose.
