Dental Research 1(1) - Fall 2010

Page 1

 UT works to expand its

name in dental research

Volume 1

Issue 1

Fall 2010

 College hires three

new research faculty, associate

 Research Spotlight:

“Effect of Aquatine endodontic cleanser on smear layer removal in the root canals of ex vivo human teeth.”

SUPPORTING THE

Dental Research OF DENTISTRY TODAY

MESSAGE from the SENIOR EXECUTIVE ASSOCIATE DEAN for RESEARCH

Welcome to the Dental Research Newsletter of the University of Tennessee College of Dentistry – just one of the new resources developed to help expand UT’s dental research program.

Whereas the College of Dentistry has traditionally used research to improve human oral health, in recent years, the commitment of the College to the development of evidence-based dentistry – clinically tested procedures, treatments, and technologies – has become much more visible. Currently, the College is working to become a stronger presence in dental research –creating the Bioscience Research Department; hiring more research-oriented faculty and staff; increasing the number of competitive grant applications; and, adding valuable resources and systems to streamline the research process for faculty, postdocs, and students.

Franklin Garcia-Godoy, D.D.S., M.S.

It is my intention with the creation of this quarterly research newsletter to improve the research communication system within the College. This newsletter will serve to increase awareness of current dental research projects and opportunities; act as a vehicle for research collaboration across departments, Colleges, and beyond the UT campus; promote the College of Dentistry’s commitment to the advancement of the health sciences and academia; and, provide recognition to faculty and students for their research contributions. During FY2010, 35% of faculty members were actively engaged in research activities, up 8% from FY2009. In addition, the College held 26 research grants, 16 more than in FY2009. As the research program expands, it should be our common goal to involve more faculty and students in research activities, and increase the amount of grant supported research. The College of Dentistry has reached a tipping point. Through our collaborated effort and continued dedication to research, the UT name will be recognized as a pacesetter, leading innovation in the field of dental research.

Edited by:

Laurel Wedel, M.A. Communications Specialist; Grants and Clinical Research Coordinator Department of Bioscience Research Direct comments to: lwedel1@uthsc.edu


Inside this Issue

RESEARCH FACULTY and STAFF

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DENTAL RESEARCH NEWS

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COLLEGE of DENTISTRY NEWS

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New research faculty, staff, and resources

QUARTERLY RESEARCH SPOTLIGHT

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CLINICAL RESEARCH

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Research study helps Aquatine endodontic cleanser receive FDA approval

PUBLICATIONS and PRESENTATIONS

10

GRANTS and SPONSORSHIPS

12

AWARDS and HONORS

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We are poised to become a leader in dental research. Dean Hottel

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Research Faculty and Staff SENIOR EXECUTIVE ASSOCIATE DEAN for RESEARCH Franklin Garcia-Godoy, D.D.S., M.S.

Chair, Department of Bioscience Research Director, Bioscience Research Center Professor, Department of Physiology, University of Tennessee Health Science Center Adjunct Professor, Department of Biomedical Engineering, University of Memphis Adjunct Professor, Department of Biomedical Engineering, Florida International University Senior Clinical Investigator, The Forsyth Institute, Boston, Massachusetts Adjunct Professor, Department of Conservative Dentistry and Periodontology, University of Munich

FACULTY

STAFF

Jegdish Babu, B.S., M.S., Ph.D. Associate Professor

Lena Haney Sr. Research Assistant

Melody Barron, D.D.S. Assistant Professor

Margaret Jefferson Sr. Research Assistant

Mustafa Dabbous, M.S., Ph.D. Professor

Geraldine Moore Lab Assistant

Edward Harris, Ph.D. Professor

Irina Vukamanovic Nosrat, D.D.S. Research Team Leader

Christopher Nosrat, D.D.S., Ph.D. Professor Mark Scarbecz, Ph.D. Professor Director of Planning and Assessment Edwin Thomas, M.S., Ph.D. Professor David Tipton, D.D.S., Ph.D. Professor

POST DOCTORAL FELLOWS Akira Ito, D.D.S., Ph.D. Research Fellow Zoran Pavicevic, M.D. Research Fellow Shailaja Kishan Rao, Ph.D. Research Fellow

Antheunis Versluis, Ph.D. Professor

Nancy Pecora, B.S.C., B.A., M.B.A. Research Coordinator Iva Pendleton Admin Service Assistant Michelle Sims, B.S. Research Coordinator Laurel Wedel, M.A. Communications Specialist Grants & Clinical Research Coordinator Yanhui Zhang, B.S., M.S., Ph.D. Research Associate

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Dental Research News

NEW ADDITIONS to the EXPANDING DENTAL RESEARCH PROGRAM

DEPARTMENT OF BIOSCIENCE RESEARCH HIRES NEW DIRECTOR OF BIOMATERIALS Dr. Antheunis Versluis, Ph.D.

Dr. Antheunis Versluis, Ph.D. recently accepted the position of Professor and Director of Biomaterials in the Department of Bioscience Research, UTHSC College of Dentistry. Dr. Versluis comes to UTHSC from the University of Minnesota – Twin Cities, where he was a Research Assistant Professor in the Department of Restorative Sciences in the School of Dentistry.

Dr. Versluis has worked in dental biomechanics and biomaterials research for over twenty years. He has extensive experience working with industrial grants to evaluate various dental materials and appliances. Dr. Versluis will assume his new position with the College of Dentistry in September 2010.

The College of Dentistry welcomes Dr. Versluis, and his wife – also a new College of Dentistry faculty member - Dr. Daranee Versluis-Tantbirojn, D.D.S., M.S., Ph.D.. (Please see below).

COLLEGE OF DENTISTRY HIRES DENTAL PUBLIC HEALTH SPECIALIST Dr. Liang Hong, D.D.S., M.S., Ph.D.

The University of Tennessee College of Dentistry welcomes Liang Hong, D.D.S., M.S., Ph.D. as a new faculty member in the Department of Pediatric Dentistry and Community Oral Health. Dr. Hong comes to UTHSC from the University of Missouri – Kansas City, where he was an Assistant Professor in the Department of Dental Public Health, in the School of Dentistry. Dr. Hong is a Board Certified Specialist in Dental Public Health. He assumed the position of Associate Professor and Director of Community Oral Health in PDCH in July 2010.

Dr. Hong brings with him to UTHSC two federally-funded research grants. His research interests include the epidemiology of oral diseases; oral health surveillance and monitoring; dental workforce issues; oral health literacy and behaviors of pregnant women; prevention and risk assessment of dental caries and fluorosis; and, hospital emergency department visits for dental care.

NEW RESEARCH FACULTY MEMBER IN RESTORATIVE DENTISTRY Dr. Daranee Versluis – Tantbirojn, D.D.S., M.S., Ph.D.

Dr. Daranee Versluis-Tantbirojn, D.D.S., M.S., Ph.D., joins her husband, Dr. Antheunis Versluis, in accepting a position with the UTHSC College of Dentistry. Dr. Versluis-Tantbirojn will be an Associate Professor in the Department of Restorative Dentistry.

Dr. Versluis-Tantbirojn was an Assistant Professor in the Department of Restorative Sciences, Division of Operative Dentistry, at the University of Minnesota – Twin Cities. She has experience with biomaterials and biomechanics research, and has received awards for her research on remineralization of carious tooth tissue. Dr. Versluis-Tantbirojn will begin this September.

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NEW RESEARCH ASSOCIATE ADDED TO BIOSCIENCE RESEARCH TEAM Dr. Yanhui Zhang, B.S., M.S., Ph.D.

The Bioscience Research Center recently hired a new Research Associate. Dr. Yanhui Zhang, B.S., M.S., Ph.D. has worked at UTHSC since 2004 in Postdoctoral Research and Research Associate positions in the Cancer Research Building. Dr. Zhang’s expertise is in microbiology, but she has extensive experience working with molecular biology and biochemical research techniques. Dr. Zhang will work in the Bioscience Research Center upon its completion, but is currently conducting research at the Craniofacial Research Center located in B12 Boling Center.

NEW RESEARCH RESOURCES NOW AVAILABLE

Research Website – Dental Research Newsletter – Dental Research Handbook In an attempt to streamline the research process, better communicate about dental research activities and opportunities, and increase awareness of dental research at UTHSC, the College of Dentistry has added new dental research resources. -

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Dental Research Website: Now available through the College of Dentistry Homepage, the Research website serves as an electronic resource for conducting dental research at UTHSC. The website includes:  Updates for research grants and deadlines  List of faculty research activities, such as publications, presentations and awards  List of research services  Research center locations and contacts  Steps to follow for conducting research  Listing of current clinical trials or research (great place for recruiting participants) To access the website, please visit: www.uthsc.edu/dentistry/research.

Dental Research Newsletter: The Dental Research Newsletter will be a quarterly publication designed to communicate research activities more effectively with faculty, staff, students, and alumni. The newsletter will serve to distinguish researchers for recent publications, presentations, and awards as well as summarize recent, relevant events, and highlight current research projects.

Dental Research Handbook:

The Dental Research Handbook, originally designed as a tool for student research, has been restructured as both a guide for student researchers as well as an informational resource of current dental research projects on campus. You can access the current Dental Research Handbook at www.uthsc.edu/dentistry/research.

FOURTEEN STUDENTS PARTICIPATE in SUMMER RESEARCH PROJECTS

Fourteen pre-doctoral dental students were awarded funds to participate in summer research projects this summer. This program allows students the opportunity to go beyond standard dental training and receive hands-on research experience in a research faculty member’s laboratory or clinic. The following is a list of the students, project titles, and faculty mentors for Summer 2010. Projects are arranged by student name and year. Second Year Dental Students (D2) Student: Title:

Mentor(s):

Student: Title: Mentor(s):

Anita Brown Efficacy of digital panoramic radiographs in detecting cortical margins of inferior alveolar nerve canal Dr. Jahanzeb Chaudhry

India Brown Effects of glove contamination on bond strengths Drs. Laura Darnell, Waletha Wasson, Franklin Garcia-Godoy 5


Student: Title: Mentor(s):

Student: Title: Mentor(s):

Student: Title: Mentor(s):

Student: Title: Mentor(s):

Student: Title: Mentor(s):

Student : Title:

Mentor(s):

Phylicia Combest The bond strengths of CEREC crowns Drs. Laura Darnell, James Simon, Franklin Garcia-Godoy

Tyler Holley Effects of cleaning solutions on resilient denture base liner color stability Drs. Laura Darnell, Russell Morrell, Franklin Garcia-Godoy

Michael A. James Removal of biofilm on hydroxyapatite disks by oral rinses Drs. Franklin Garcia-Godoy, Jegdish P. Babu

Bryan Lee Bonding of hybrid posterior composite materials Drs. Laura Darnell, Robert Hatch, Franklin Garcia-Godoy

Tiffany Stuart Color changes of denture base resins associated with the use of denture cleansers Drs. Franklin Garcia-Godoy, Scott Hollis, Laura Darnell

Brian Wah Confidence level in diagnosing proximal caries: A comparison between bitewing radiographs acquired with F-speed film and hi-resolution solid state image detector Dr. Jahanzeb Chaudhry

Student : Title: Mentor(s):

Nia Zacharia Effects of cranberry components on human gingival epithelial cells Drs. David Tipton, Swati R. Rawal

Student: Title: Mentor(s):

Shawna R. Clark Analysis of biofilms accumulated on composite resins Drs. Franklin Garcia-Godoy, Jegdish P. Babu

Third Year Dental Students (D3)

Student: Title: Mentor(s):

Student: Title: Mentor(s):

Student: Title: Mentor(s):

Student: Title: Mentor(s):

Nathaniel Denson Effect of handpiece lubrication on the composite bond Drs. Laura Darnell, Janet Harrison, Franklin Garcia-Godoy

Ashlee Franklin Tumor biomarker protein uPA expression in cultured normal and tumor cells Drs. Mustafa Kh. Dabbous, Edwin L. Thomas

Erin Claire Stanford Effect of water line disinfectants on the composite bond Drs. Laura Darnell, Bernard Blen, Franklin Garcia-Godoy

Britney Taylor Genotoxicity of dental restorative composites on gingival fibroblasts Drs. Franklin Garcia-Godoy, David A. Tipton, Jegdish Babu

*The Student Summer Research Program is supported by the UT Dental Alumni Endowment and the Tennessee Dental Association Foundation.

REMINDER: 2010 HINMAN STUDENT RESEARCH SYMPOSIUM October 29-31, 2010

The Hinman is co-sponsored by the University of Tennessee College of Dentistry and the Thomas P. Hinman Dental Society, with participation by

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College of Dentistry News

IMPORTANT NOTICE: COLLEGE of DENTISTRY DEPARTMENT NAME CHANGES As of July 1, 2010, the following College of Dentistry departments underwent name changes: • • •

Restorative Dentistry is now the Department of Prosthodontics Endodontics is a standalone department Operative Dentistry is new Department of Restorative Dentistry

RENOVATIONS: PHASE TWO

The renovations for the Dunn Dental Building continues. April 2010 marked the completion of Phase One, during which the Department of Pediatrics received a new child-friendly waiting room and the graduate pediatric program received its own designated space, equipped with new chairs, units, cabinetry, and flooring. Phase One also saw the complete renovation of the fourth floor, which houses the predoctoral training clinic.

Phase Two was approved by the State Building Commission in July 2010 and is currently underway. During Phase Two, the Bioscience Research Center will be gutted and designed as a state-of-the-art dental research lab. The third floor will house the University Dental Practice and a new Clinical Research Center. The fifth floor renovations will produce updated clinics for Graduate Prosthodontics and Periodontology. Dental Hygiene, Endodontics, and AEGD will also be housed on the fifth floor.

A special thanks to the Dental Alumni who have helped make these renovations possible. Despite the short-term set-backs that the construction will make, the long-term benefits of this renovation will help distinguish UT as a leader in Dentistry.

DELTA DENTAL of ARKANSAS DONATES $500K to COLLEGE of DENTISTRY Delta Dental of Arkansas just announced a planned donation to the College of Dentistry for the amount of $500,000. This donation will be used to add ten new work stations and make changes to the electronic delivery system in the General Education Building (GEB) pre-doctoral laboratory. This will bring the total number of available stations to 90.

Delta Dental of Tennessee also donated $1.5 million to update the Dental Simulation lab. The new DentSim lab is located in the General Education Building (GEB) and is used by first and second year dental students to gain valuable experience before entering the clinics.

GRADUATE ORTHODONTIC CLINIC GETS NEW LOOK and NEW NAME

The University of Tennessee Orthodontic Alumni announced on May 27th that the new renovations to the Graduate Orthodontic Clinic would be named for Dr. James Vaden, former Chair of the Department of Orthodontics. Dr. Vaden has been a faculty member of the College for 30 years and has served as department chair since 1999. In naming the renovations for him, Dr. Vaden will be remembered by future generations for his efforts to make the program one of the best in the nation. The Orthodontic Alumni also announced that they have raised nearly $700k in commitments to the clinic, which puts the College well on its way to reaching its goal of $750k. 7

James Vaden, D.D.S.


Research Spotlight

RESEARCH STUDY HELPS AQUATINE ENDODONTIC CLEANSER RECEIVE FDA APPROVAL Dr. Franklin Garcia-Godoy, Senior Executive Associate Dean for Research, recently had a research article* accepted for publication in the Journal of Applied Oral Science. Below is the abstract of that study.

Objectives: The purpose of this study was to measure and compare the root canal cleanliness and smear layer removal effectiveness of Aquatine Endodontic Cleanser (Aquatine EC) when used as an endodontic irrigating solution in comparison with 6% sodium hypochlorite (NaOCl).

Material and Methods: Forty-five human teeth were randomly allocated to five treatment groups; the pulp chamber was accessed, cleaned and shaped by using ProTaper and ProFile rotary instrumentation to an ISO size #40. The teeth were then processed for scanning electron microscopy, and the root canal cleanliness and removal of smear layer were examined. Results: The most effective removal of smear layer occurred with Aquatine EC and NaOCl, both with a rinse of EDTA. (See Figures 1-5 on right).

Conclusions: Aquatine EC appears to be the first hypochlorous acid approved by the FDA to be a possible alternative to the use of NaOCl as an intracanal irrigant. Further research is needed to identify safer and more effective alternatives to the use of NaOCl irrigation in endodontics.

Based on this study by Dr. Murray and Dr. Garcia-Godoy, the FDA approved Aquatine Endodontic Cleanser for market use as an endodontic irrigant. Below is an excerpt from the PuriCore press release announcing receipt of its FDA approval.

“Furthermore, when used in combination with EDTA, Aquatine EC was highly effective at disinfecting tooth root canals contaminated with bacteria when compared to bleach. The independent study, sponsored by PuriCore, was led by Drs. Murray and Garcia-Godoy and conducted by Drs. Garcia, Kuttler, and Namerow at Nova Southeastern University College of Dental Medicine. In 2006, PuriCore received 510(k) clearance from the US Food and Drug Administration (FDA) allowing it to market its proprietary Aquatine EC endodontic cleanser as a medical device in the United States.�

*Garcia F, Murray PE, Garcia-Godoy F, Namerow KN. Effect of aquatine endodontic cleanser on smear layer removal in the root canals of ex vivo human teeth. Journal of Applied Oral Science. 2010 Aug; 18(4):403-8.

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Clinical Research

The following is a list of current clinical research studies being conducted by UT College of Dentistry faculty. The title, investigators, and study objective are listed for each project.

A clinical study to evaluate the safety and efficacy of high-adhesion whitening strips under extended wear regimen relative to marketed control Study Objective:

The primary objective of this study is to evaluate the safety and efficacy for extended wear of a 10% H2O2 High-Adhesion Whitening Strip relative to a marketed control.

Principal Investigator:

Dr. James Simon

Co-Investigators:

Dr. Llewellyn Powell and Dr. Maurice Lewis

Research Staff:

Nancy Wilson (Study Coordinator)

A comparison of the effects of occlusal adjustment and splint therapy on symptoms reduction in TMD Study Objective:

The purpose of this study is to compare the effectiveness of occlusal adjustment and splint therapy on the therapeutic management of temporomandibular dysfunction (TMD).

Principal Investigator:

Dr. Swati Ahuja

Co-Investigators:

Dr. David Cagna and Dr. William McHorris

Assessment of Oral Health in a Population from the Memphis Area Study Objective:

The objective of this study is to assess prevalence of caries, plaque (including plaque acidogenicity and periodontal pathogens), gingivitis, calculus, facial stain, and visible signs of periodontal disease in a population of subjects from the Memphis area.

Principal Investigator:

Dr. Franklin Garcia-Godoy

Co-Investigators:

Dr. Laura Darnell and Dr. Llewellyn Powell

Research Staff:

Laurel Wedel (Research Coordinator) Dr. Aleena Shahiryar (Research Volunteer)

Daily intake of aspirin and periodontal therapy in smokers Study Objective:

The goal of this double-blind, randomized study is to determine the effects of daily dose of 325 mg of ASA on the clinical outcomes of scaling and root planning on a group of 24 adult smokers.

Principal Investigator:

Dr. Jacob Shiloah

Co-Investigators:

Dr. Paul Bland, Dr. Mark Scarbecz, Dr. David Tipton, Dr. Mark Patters, and Dr. Sid Stein

Oral Streptococus species in pre-term and full-term 24-36 month old African-American children in Memphis, Tennessee – A crosssectional study Study Objective:

The study objective is to investigate five Streptococcus species commonly found in the oral biofilm of children, specifically Streptococcus mutans, Streptococcus sobrinus, Streptococcus mitis, Streptococcus sanguinis, and Streptococcus salivarius to determine their relative numbers in 24-36 month old healthy African-American pre-term and full-term children residing in Memphis, Tennessee.

Principal Investigators:

Dr. Franklin Garcia-Godoy and Dr. Renalie Rebong

Co-Investigators:

Dr. Jegdish Babu and Dr. Reddy Dhanireddy

Research Staff:

Laurel Wedel (Research Coordinator) 9


Publications Presentations

The following is a list of publications and presentations by College of Dentistry faculty from January 2010 to Present:

PUBLICATIONS

Adatrow PC, Hilal G, Cagna D., Bland, P. Iatrogenic peri-implantitis: Treatment and once to two year follow-up. The Journal of Implant & Advanced Clinical Dentistry. February 2010. Ahuja S, Wicks RA, Brandt RL. Developing a fixture level cast for implants with interfering axial convergence. J Tenn Dent Assoc. Spring 2010; 90(2).

Ahuja S, Cagna DR. Defining available restorative space for implant overdentures. J Prosthet Dent. 2010; 104(2):133-36.

Aubertin M, (the late) Horbelt C, Wasson W, Woods M. Medication use in geriatric populations: Dental implications of frequently prescribed medications. Gen Dent. 58(2), 100-107. March/April 2010. Donovan TE, Becker W, Cagna DR, Hilton TJ, Rouse, J. Annual review of selected scientific literature: Report of the Committee on Scientific Investigation of the American Academy of Restorative Dentistry. J Prosth Dent. July 2010; 104(1):13-47. Cardenas LM. Effects of an oral health education program for pregnant women. J Tenn Dent Assoc. Spring 2010; 90(2).

Darnell LA, Teaford MF, Livi KJ, Weihs TP. Variations in the mechanical properties of Alouatta palliata moral enamel. Am J Phys Anthropol. 2010 Jan; 141(1):7-15. Souza JG, Bianchini M, Ferreira CF. Relationships between smoking and bleeding on probing. J Oral Implantol. 2010 Aug 6 [Epub ahead of print]. Garcia-Godoy F, Kramer N, Feilzer AJ, Frankenberger R. Long-term degradation of enamel and dentine bonds: 6-year results in vitro vs. un vivo. Dent Mater, in press. 2010.

Alvarez-Serrano S, Garcia-Godoy F, Pameijer CH, Zmener O. Sealing properties of a calcium alumniate agent. Am J Den. 2010; 23:121-124.

Ayad MF, Farag AM, Garcia-Godoy F. Effect of lactic acid irrigation on shear bond strength of Epiphany adhesive sealer to human dentin surface. Oral Surg Oral Med Oral Path Oral Radiol, Endod. 2010; 109:e100-e106 Ayad MF, Maghrabi AA, Garcia-Godoy F. Resin composite polyethylene fiber reinforcement: Effect on fracture resistance of weakened marginal ridges. Am J Dent. 2010;23:133-136.

Ayad MF, Maghrabi AA, Garcia-Godoy F. Relationship of margin design for fiber-reinforced composite crowns to compressive fracture resistance. J Prosthod. 2010 Aug [Epub ahead of print].

Bahuleyan B, Chadipiralla K, Garcia-Godoy F, Huang CY, Murray PE, Stelnicki EJ, Yochim JM. Osteogenic differentiation of stem cells derived from human periodontal ligaments and pulp of human exfoliated deciduous teeth. Cell Tissue Res. 2010. Mar 23 [Epub ahead of print]. Bento LW, Casagrande L, Dalpian DM, de Araujo FB, Garcia-Godoy F. Indirect pulp treatment in primary teeth: 4- year results. Am J Den. 2010; 23(1):34-8. 10


Kuhnisch J, Bucher K, Henschel V, Albrecht A, Garcia-Godoy F, Mansmann U, HIckel R, Heinrich-Weltzien R. Diagnostic performance of the universal visual scoring system (UniViSS) on occlusal surfaces. Clin Oral Investig. 2010 Mar 11 [Epub ahead of print]. Osorio R, Aguilera FS, Otero PR, Romero M, Osorio E, Garcia-Godoy F, Toledano M. Primary dentin etching time, bond strength and ultra-structure characterization of dentin surfaces. J Dent. 2010 Mar; 38(3):222-31. Park SB, Son WS, Ko CC, Garcia-Godoy F, Park MG, Kim HI, Kwon YH. Influence of flowable resins on the shear bond strength of orthodontic brackets. J Dent Mater. 2009 Nov; 28(6)730-4.

Ritts AC, Li H, Yu Q, Xu C, Yao X, Hong L, Wang Y. Dentin surface treatment using a non-thermal argon plasma brush for interfacial bonding improvements in composite restoration. Euro J Oral Sci. 2010 Oct; 118(5):510-516. King KA, Powell L. Quick and easy: Indirect fabrication of composite veneers. J Tenn Dent Assoc. Spring 2010; 90(2).

Ito A, Nosrat IV, Nosrat CA. Taste cell formation does not require gustatory and somatosensory innervations. Neurosci Lett. 2010 Mar 8; 471(3):189-94. Migliorati C, Mattos K, Palazzolo M. How patients’ lack of knowledge about oral bisphosphonates can interfere with medical and dental care. J Am Dent Assoc. 2010;141;562-566.

Rao SK, Pavicevic Z, Du Z, Kim JG, Fan M, Jiao Y, Rosebush M, Samant S, Gu W, Pfeffer LM, Nosrat CA. Pro-inflammatory genes as biomarkers and therapeutic targets in oral squamous cell carcinoma. J Biol Chem. 2010 Aug [Epub ahead of print]. Rosebush MS, Anderson KM, Rawal SY, Mincer HH, Rawal YB. The oral biopsy: Indications, technique, and special considerations. J Tenn Dent Assoc. Spring 2010; 90(2).

Russell CK, Shreve R, Hofmann P, Scarbecz M, Scheid C, Brescia W, Schwab C, Robinson MM. Assessing teaching activities on an academic health science center campus. Transformative Dialogues: Teaching and Learning E-Journal. 2010; March. Tipton DA, Seshul BA, Dabbous MK. Effect of bisphosphonates on human gingival fibroblast production of mediators of osteoclastogenesis: RANKL, OPG, and IL-6. J Periodont Res. 2010; 14(3).

PRESENTATIONS

Drs. Paul Bland, Mark Patters, Mark Scarbecz, Jacob Shiloah, Sid Stein, and David Tipton gave a presentation at the International Association for Dental Research Annual Meeting (July 14-17, 2010) in Barcelona, Spain. This presentation discussed findings from their ongoing research project. Title: The effect of long-term aspirin intake on the outcome of non-surgical periodontal therapy in smokers. Dr. Franklin Garcia-Godoy, Senior Executive Associate Dean for Research, was invited to present a two hour lecture at the International Dental Federation (FDI) meeting in Brazil this September. Session Title: Management of the Pedodontic Patient – A Current Evidence-Based Approach. The International Dental Federation Meeting was held in Salvador de Bahia, Brazil on September 2-5, 2010. Drs. Kenneth King, Lew Powell and Jim Simon presented a poster at the AADR Annual Meeting in Washington, D.C. on March 4, 2010. This poster documented the dentists’ recent clinical research study. Title: Clinical comparison of high-adhesion whitening strips and professional laser-assisted whitening.

Dr. Adam Lloyd has been invited to Lyon, France to give a presentation to the French Society of Endodontics on June 17th-19th, 2011.

Dr. James Simon and two D4 students (Jennifer Hill and Nathaniel Hill) presented a poster at the 25th Celebration of CEREC, which was held in Las Vegas on August 26th-28th. Title: Tensile bong strength of ceramic crowns using resin cement.

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Grants Sponsorships

The following is a list of current grants/sponsorships held by UT College of Dentistry faculty.

FEDERAL/FOUNDATION GRANTS •

Influence of cranberry juice components on denture related stomatitis and inflammatory reactions of gingival fibroblasts o PI: Jegdish Babu, B.S., M.S., Ph.D. (Bioscience Research) o Co-PI: David Tipton, D.D.S., Ph.D. (Bioscience Research) o Cranberry Institute of Wisconsin (Private Grant)

Biocompatibility screening of restorative treatments o PI: Franklin Garcia-Godoy, D.D.S., M.S. (Sr Exec Assoc Dean for Research/Bioscience Research) o NIH/NIDCR (R01)

Preclinical effectiveness of cytotoxicity assays o CI: Franklin Garcia-Godoy, D.D.S., M.S. (Sr Exec Assoc Dean for Research/Bioscience Research) o NIH/NIDCR (R03)

Biocompatibility screening of restorative treatments o PI: Franklin Garcia-Godoy, D.D.S., M.S. (Sr Exec Assoc Dean for Research/Bioscience Research) o NIH High Priority, Short-Term Project Award (R56

Hinman Student Research Symposium o PI: Franklin Garcia-Godoy, D.D.S., M.S. (Sr. Exec Assoc Dean for Research/Bioscience Research) o NIH/NIDCR (R13)

Neurotrophin Specificity and Function in the Taste System o PI: Christopher Nosrat, D.D.S., Ph.D. (Bioscience Research) o NIH/NIDCD Research Grant (R01)

Neurotrophin Specificity and Function in the Taste System o PI: Christopher Nosrat, D.D.S., Ph.D. (Bioscience Research) o NIH/NIDCH (ARRA Funding Supplement to R01)

Roles of NGF in Familial Dysautonomia o CI: Christopher Nosrat, D.D.S., Ph.D. (Bioscience Research) o NIH/NINDS Research Grant (R01)

SPONSORSHIPS •

A Clinical Study to Evaluate the Safety and Efficacy of High-Adhesion Whitening Strips Under Extended Wear Regimen Relative to a Marketed Control o PI: James Simon, D.D.S., M.Ed., (Restorative Dentistry) o Procter & Gamble

Visualization of sealer movement during single-cone obturation with EndoSequence BC Sealer o PI: Adam Lloyd, B.D.S., M.S. (Endodontics) o Real World Endodontics/Brasseler USA 12


Awards Honors

Franklin Garcia-Godoy, D.D.S., M.S., Senior Executive Associate Dean for Research, was recently invited to serve as chair of the Craniofacial and Dental Tissue Engineering session of the Scientific Advisory Committee of 2010 Tissue Engineering and Regenerative Medicine International Society (TERMIS) North America (NA). The TERMIS NA 2010 Conference and Exposition will be held in Orlando, FL from December 6-8, 2010.

The Tissue Engineering and Regenerative Medicine International Society (TERMIS) is the most prestigious group working in this area in the world.

Waletha Wasson, D.D.S., Associate Professor in the Department of Restorative Dentistry was recently among 50 honorees for the Women of Excellence Awards presented by the Tri-State Defender on April 30, 2010. The Defender is a Memphis-area newspaper that highlights issues of interests to African-Americans. Dr. Wasson was recognized for her leadership role in the Tennessee Smiles program, an initiative that provides complementary dental screenings and oral health information to underserved adults and children at health fairs in the Mid-South region. Dr. Wasson is a founder of Tennessee Smiles, which began in 2003. Dr. Wasson continues to lead the Tennessee Smiles program and is involved in clinical investigations of cultural competency and literacy in healthcare.

Dr. James Simon and two UTHSC D4 students (Jennifer Hill and Nathaniel Hill) received 1st place for their poster presentation at the 25th Celebration of CEREC, which was held in Las Vegas on August 26th-28th. The poster presentation (Tensile bong strength of ceramic crowns using resin cement) was on the two students’ summer research project in which Dr. Simon was the mentoring faculty.

REMINDER – UPCOMING ALUMNI ENDOWMENT FUND DEADLINE The University of Tennessee College of Dentistry Alumni Endowment Fund will begin accepting applications this fall for the October 2010 cycle.

The Alumni Endowment Fund seeks proposals from faculty and students for funding to support clinical research and professional development within the College. The Endowment accepts proposals on a semiannual basis with application deadlines falling on the last Friday of April and October of each year. This cycle’s deadline is Friday, October 29th.

Since 1988, the Endowment Fund has allowed up to a maximum of $15,000 for Category I Research Grants, and since 1991, has allowed up to $2,500 in Category II Professional Development Grants. For a copy of the full grant guidelines, please contact Laurie, Grants & Clinical Research Coordinator, at 448-2210 or lwedel1@uthsc.edu.

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ABOUT the COLLEGE of DENTISTRY The UTHSC College of Dentistry was founded in 1878 making it the oldest dental college in the South, and the third oldest public college of dentistry in the United States.

The College contains a 4-year dental program, totaling approximately 320 students. In addition, students in the Postgraduate dental programs and Dental Hygiene are included.

The College is dedicated to providing professional, graduate, and postgraduate education; conducting dental research; and, delivering state-of-the-art patient care and public service.

College of Dentistry 875 Union Avenue Memphis, TN 38163 Phone: (901) 448-6200 Fax: (901) 448-1625

FOR MORE INFORMATION ABOUT THE UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER, VISIT: www.uthsc.edu

The University of Tennessee is an EEO/AA/Title VI/Title IX/Section 504/ADA/ADEA institution in the provision of its education and employment programs and services.

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