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 The Hinman Student

Research Symposium 2010

Volume 1

Issue 2

Winter 2011

Construction continues at

the College of Dentistry

 Research Spotlight:

Dr. Simon’s Esthetic Dentistry Research

SUPPORTING THE

Dental Research OF DENTISTRY TODAY

MESSAGE from the SENIOR EXECUTIVE ASSOCIATE DEAN for RESEARCH

Welcome to the second issue of Dental Research, the research newsletter of the College of Dentistry at the University of Tennessee. Another year is over and a new one has just begun. What do you see in the year ahead? I see opportunity. I see the future of dentistry.

Taking a glimpse back over 2010, it is easy to see that the College of Dentistry as a whole is headed in a new direction – one toward modernization and innovation. The main changes have been esthetic as the equipment and facilities in the dental clinics are moving out of the 1970s and into the 2010s. The new look not only provides a polish to the clinics but also allows the students to gain experience working with state-of-the-art equipment while serving the needs of their patients. In addition, the College of Dentistry witnessed many faculty changes – with the addition of many new research-focused faculty and the loss of a few long familiar faces.

Franklin Garcia-Godoy, D.D.S., M.S.

Dental research also added new faculty in 2010. Dr. Antheunis Versluis was hired as the new Director of Biomaterials and Dr. Melody Barron was brought on as a craniofacial pain and sleep disorder specialist, directing the new TMD/Sleep Disorder Clinic. The Department of Bioscience Research also expanded its research team with two new research associates and a grants and clinical research coordinator.

Dental research is also benefiting from the renovations in the College, with the development of the Bioscience Research Center and Clinical Research Center. These new centers will be two new areas in Dunn Building that are dedicated to research. The former will add an additional 600 square feet of laboratory space and modern equipment. The latter will be the first area specifically designed for clinical research. It will include three exam chairs, a privacy room for consultations, a waiting area, and a private work station for researchers and sponsors. Looking over these exciting changes in the College and in dental research, it is difficult not to see potential for 2011. With 365 days of opportunity, why not lend your expertise to a research project this year and have an impact on the future of dentistry, today.

Edited by:

Laurel Wedel, M.A. Grants and Clinical Research Coordinator Department of Bioscience Research Direct comments to: lwedel1@uthsc.edu

Inside this Issue

RESEARCH FACULTY and STAFF

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DENTAL RESEARCH NEWS

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COLLEGE of DENTISTRY NEWS

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QUARTERLY RESEARCH SPOTLIGHT

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CLINICAL RESEARCH

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New Research Team Members – Hinman Student Research Symposium 2010

Whitening your Smile: Dr. James Simon’s Esthetic Dentistry Research

PUBLICATIONS and PRESENTATIONS

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GRANTS and SPONSORSHIPS

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AWARDS and HONORS

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Research is to see what everybody else has seen, and to think what nobody else has thought.

Albert Szent-Gyorgyi Hungarian Biochemist 1937 Nobel Prize Winner for Medicine

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Research Faculty and Staff SENIOR EXECUTIVE ASSOCIATE DEAN for RESEARCH Franklin Garcia-Godoy, D.D.S., M.S.

Chair, Department of Bioscience Research Director, Bioscience Research Center Professor, Department of Physiology, University of Tennessee Health Science Center Adjunct Professor, Department of Biomedical Engineering, University of Memphis Adjunct Professor, Department of Biomedical Engineering, Florida International University Senior Clinical Investigator, The Forsyth Institute, Boston, Massachusetts Adjunct Professor, Department of Conservative Dentistry and Periodontology, University of Munich

FACULTY

STAFF

Jegdish Babu, B.S., M.S., Ph.D. Associate Professor

Brandy Clark, CDA, RDA Clinical Dental Assistant

Melody Barron, D.D.S. Assistant Professor Director, TMD/Sleep Disorder Clinic

Kimberly DeMonaco, R.D.H. Clinical Research Associate Margaret Jefferson Sr. Research Assistant

Mustafa Dabbous, M.S., Ph.D. Professor

Geraldine Moore Lab Assistant

Edward Harris, Ph.D. Professor

Irina Vukamanovic Nosrat, D.D.S. Research Team Leader

Christopher Nosrat, D.D.S., Ph.D. Professor

Nancy Pecora, B.S.C., B.A., M.B.A. Research Coordinator

Mark Scarbecz, Ph.D. Professor Director of Planning and Assessment

Iva Pendleton Admin Service Assistant

Edwin Thomas, M.S., Ph.D. Professor

Michelle Sims, B.S. Research Coordinator

David Tipton, D.D.S., Ph.D. Professor

Linda Vincent TMD/Sleep Disorder Clinic Coordinator

Antheunis Versluis, Ph.D. Professor Director of Biomaterials

Laurel Wedel, B.A., M.A. Grants & Clinical Research Coordinator

POST DOCTORAL FELLOWS

Yanhui Zhang, B.S., M.S., Ph.D. Research Associate

Akira Ito, D.D.S., Ph.D. Research Fellow Shailaja Kishan Rao, Ph.D. Research Fellow

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Dental Research News

PLEASE WELCOME our NEW DENTAL RESEARCH STAFF

DENTAL HYGIENIST JOINS BIOSCIENCE RESEARCH DEPARTMENT Kimberly S. DeMonaco, R.D.H.

Kimberly S. DeMonaco, R.D.H. recently joined the dental research team in the Bioscience Science Research Department. Kimberly will be a Clinical Research Associate, working primarily for the Clinical Research Center, which will be developed later this spring. Kimberly comes to UTHSC with extensive dental hygiene experience and experience working in higher education. Prior to starting at UTHSC, Kimberly was working at Nova Southeastern University in Ft. Lauderdale, FL. Kimberly started with UTHSC in October and has already begun working on some of the Bioscience Research clinical research studies. Once complete, Kimberly will be working out of the new Clinical Research Center on the 3rd floor of the Dunn Dental Building.

BIOSCIENCE RESEARCH WELCOMES TMD/SLEEP DISORDER CLINIC STAFF Melody Barron, D.D.S. – Brandy Clark, CDA, RDA – Linda Vincent

The Department of Bioscience recently hired Dr. Melody Barron as its craniofacial pain and sleep disorder specialist. Dr. Barron is a Fellow of the American Academy of Craniofacial Pain and a Diplomat of the Academy of Clinical Sleep Disorder Dentistry. She is responsible for oversight of the new TMD/Sleep Disorder Clinic. Dr. Barron is a 1992 graduate from the University of Tennessee College of Dentistry. She worked as a general dentist in private practice from 1992-2005. In 2005, she focused her work on the treatment of TMD and sleep disorders. In July 2010, Dr. Barron became the director of the new TMD/Sleep Disorder clinic , located in the University Dental Practice (UDP).

Dr. Barron brings with her Brandy Clark, C.D.A., R.D.A. and Linda Vincent. Brandy Clark has fourteen years of experience as a dental assistant. She is a certified TMJ Assistant through the American Academy of Craniofacial Pain. She also holds a lab certification through the TMJ and Sleep Therapy Centre Certified Laboratory program. Linda Vincent is the clinic coordinator. She has over 30 years of experience, working with Dr. Barron in the care of patients with TMJ/Sleep Disorders for over four years.

COLLEGE of DENTISTRY STUDENT WINS TRAVEL AWARD from NIDCR

A fourth year College of Dentistry student (D4) received a travel award from the National Institute of Dental and Craniofacial Research (NIDCR). Ashlee Franklin won a $1,100 travel award to be used for her to attend the American Association for Dental Research (AADR) international meeting and present her summer research project. The AADR meeting with be held March 16-19 in San Diego, California.

Ms. Franklin was one of a few students from across the United States who was selected to receive a travel award from the NIDCR. This award is given to recognize outstanding students in dental research. Ms. Franklin received this recognition and travel award for her project titled: Correlation of Urokinase Plasminogen Activator Expression with Metastatic Potential. This summer research project was supported by the UT College of Dentistry Alumni Endowment Fund and the Sam Mount Jr. Endowment. The project was directed by Dr. Mustafa Kh. Dabbous, with assistance from Dr. E.L. Thomas, M. Jefferson, and A. Shahiryar.

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HINMAN STUDENT RESEARCH SYMPOSIUM 2010 The16th Annual Hinman Student Research Symposium was held this past October on the 29th – 31st at the Peabody Hotel in Memphis. The Symposium featured oral and poster research presentations from dental pre-doctoral students. A total of eighty-six students participated in the Symposium, representing forty-seven dental colleges from twenty-nine states, the District of Columbia, and three Candadian provinces. There were fourteen dental students from the University of Tennessee who presented their summer research projects and acted as hosts for the event.

The Symposium began with an opening address from Dr. Franklin Garcia-Godoy, Senior Executive Associate Dean for Research, and a welcome by Dr. Brian Carpenter, President of the Hinman Dental Society. Dr. Leslie Frieden, Extramural Training Officer of the National Institute of Dental and Craniofacial Research (NIDCR), also addressed the students and emphasized the use of NIDCR for research training support and the career opportunities for future leaders in clinical and translational research.

Dr. Dominick P. DePaola, Associate Dean for Academic Affairs at Nova Southeastern College of Dental Medicine, provided Friday evening’s opening keynote speech, titled “Recent Advances and Translation to Clinical Practice.” He focused on the need to accelerate the process of transfering new scientific discoveries from the laboratory to clinical practice in order to improve oral health care worldwide. Also on Friday evening, Dr. Mustafa Dabbous, Professor of Bioscience Research at UTHSC College of Dentistry, was honored for his foresight in establishing the first Hinman Student Research Symposium in 1995 and his continuing direction and support of student research throughout the years.

Six research projects received awards for most outstanding student presentations – three were in clinical research and three were in basic science research. (Please see list of award-winning presentations below). In addition, one presentation won the 2010 President’s Award for Excellence in Dental Research from the National Students Research Group (NSRG) of the American Association for Dental Rsearch.

The 16th Annual Hinman Student Research Symposium was co-sponsored by the University of Tennessee Health Science Center College of Dentistry and the Hinman Dental Society. The event was also generously supported by the National Institute of Dental and Craniofacial Research, the Procter & Gamble Company, the ADEAgies Foundation, Colgate, and the Tennessee Dental Association Foundation.

MOST OUTSTANDING PRESENTATIONS in CLINICAL RESEARCH

Oral Complications Associated with Chronic GVHD and their Impact on Qualify of Life: A Pilot Study Courtney Grady, S. Zwetchkenbaum, C.A. Murodch-Kinch, C. Kitko, and T. Braun University of Michigan, Ann Arbor

Surface Roughness of In-Office Machined Crowns Using Diamond Burs Klye A. Malloy, J.C. Mitchell, C.M. Malloy Oregon Health & Science University, Portland

LBR Negatively Modulates Survivin (BIRC5) in Human Oral Cancers Blake M. Warner, T.J. Knobloch, L. Uhrig, D.K. Pearl, B.C. Casto, A. Agrawal, D.E. Schuller, T.N. Teknos, E. Ozer, SK Clinton, C.M. Weghorst The Ohio State University, Columbus

MOST OUTSTSNDING PRESENTATIONS in BASIC SCIENCE RESEARCH

Investigating the Physiologic and Pathologic Roles of Integrin ανβ6 Caitlin Magraw, P. Brinton, A. Bandopadhyay, S. Raghavan Columbia University, New York Regulation of Human Bmp4 Promoter by Pax9, Mxxi and Msx Manshi Patel, G. Mues, R. D’Souza Texas A&M Health Science Center, Dallas 5

Sprouty2 Down-regulates Angiogenesis During Mouse Skin Wound Healing Mateusz S. Wietecha, L. Chen, M.J. Ranzer, K. Anderson, C. Ying, T.B. Patel, L.A. Di Pietro University of Illionis, Chicago & Loyola University, Maywood, IL

2010 PRESIDENT’S AWARD for EXCELLENCE in DENTAL RESEARCH from the NATIONAL STUDENTS RESEARCH GROUP of the AMERICAN ASSOCIATION for DENTAL RESEARCH Identifying the Function of Tgfβr3 in Submandibular Gland Morphogenesis Angelo G. Pope, Jr., M.P. Hoffman, V.N. Patel Howard University, Washington, D.C. & NIDCR, Bethesda, Maryland

Student participants, mentors and distinguished guests at the 2010 Hinman Student Research Symposium

Mark Your Calendars! UNIVERSITY of TENNESSEE COLLEGE of DENTISTRY presents

STUDENT RESEARCH DAY Tuesday, February 15, 2011 11:00 – 5:00 pm Student Alumni Center (SAC) Activities include poster and table presentations from student researchers and a keynote address from a distinguished dental researcher.

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College of Dentistry News

COLLEGE of DENTISTRY REMODEL CONTINUES

Last year was another busy year of construction in the College of Dentistry. As the 4th floor clinic renovations were completed, construction began on the 2nd floor pre-doctoral pediatric clinic and oral diagnostic sciences. And this January and February, work will start on the dental administration offices and the Bioscience Research Center, and on the graduate periodontology and prosthodontics clinic on the 5th floor. In late February, the 3rd floor private practice and Clinical Research Center are scheduled to undergo renovations.

Despite the noise and dust that comes with as extensive a construction project as this, the improvements can be noticed throughout, and are indicators of the direction in which the College of Dentistry is headed.

DR. WISDOM COLEMAN, D.D.S., M.P.H.A. ASSOCIATE DEAN of ADMISSIONS, 1997-2010

The College of Dentistry mourns the passing of Dr. Wisdom F. Coleman in July 2010. Dr. Coleman served the College as the Associate Dean of Admissions from 1997-2010. He received his B.S. and D.D.S. from Howard University and his Masters of Public Health Administration from the University of Memphis. He was in private practice from 1972-2002, and has been affiliated with the College of Dentistry at the University of Tennessee since 1971. Dr. Coleman’s efforts to build an exceptional student body helped create and maintain the strong dental workforce in Tennessee and Arkansas.

Dr. Coleman impacted many lives during his time with the College of Dentistry and he will be missed by all on the University of Tennessee Health Science Center campus.

UNIVERSITY of TENNESSEE HEALTH SCIENCE CENTER : 100 YEARS ADVANCING HEALTH CARE Two thousand and eleven marks the centennial of the University of Tennessee Health Science Center. Founded in 1911 in the heart of what is now the Memphis Medical Center, the University has educated and trained more than 53,000 health care professionals on campus and in health care facilities across the state. The University of Tennessee Health Science Center and its affiliated teaching hospitals provide more than one million days of inpatients services and more than two million visits annually.

To commemorate this historic first century, the University is planning a variety of special events for 2011. These events include a lecture series, a 5k run/walk, and a celebratory gala, which is scheduled to take place on the Memphis campus this September. In addition, the University also created a commemorative book, titled The Legacy The Future: A Centennial Portrait of the University of Tennessee Health Science Center. This book is a coffee table book that provides snapshots of the past and present, and portrays the UTHSC of the future. These books are available for purchase through the University of Tennessee Health Science Center bookstore located at the 930 Madison Avenue plaza in Memphis. For more information about centennial events, visit the University of Tennessee Health Science Center homepage at www.uthsc.edu. 7

Research Spotlight

WHITENING your SMILE: DR. SIMON’S ESTHETIC DENTISTRY RESEARCH Are you looking for an expert in vital teeth whitening? Look no further than the University of Tennessee’s (UT) own Dr. James Simon. Since July of 2000, Dr. Simon has been a professor in the Department of Restorative Dentistry and the Director of Esthetic Dentistry. Dr. Simon has worked extensively with esthetic dentistry and has been conducting clinical research studies in vital teeth whitening for more than 12 years.

BACKGROUND

Dr. Simon first began conducting whitening studies at the University of Pacific in San Francisco, James Simon, D.D.S. where he collaborated with The Procter & Gamble Company (P&G) to conduct a clinical trial of Crest White Strips® when this product first came to the market in 1998. In 2000, when Dr. Simon accepted a position at the University of Tennessee Health Science Center (UTHSC), he continued his research relationship with P&G. Then in 2003, Dr. Simon held his first teeth whitening study at UTHSC.

WHITENING AT UTHSC

From 2003 to 2010, Dr. Simon has conducted ten studies with P&G. These studies examined the effectiveness, longevity, and sensitivity caused by various whitening products – including professional laser treatments, commercially available tray bleaching kits, and various versions of whitening strips. Contributing to these successful research studies are six faculty members: Drs. Janet Harrison, Scott Hollis, Kenneth King, Mark Lackey, Maurice Lewis, and Lew Powell, who participated as examiners on these projects. Another vital team member was Nancy Wilson, who served as study coordinator on each of these studies.

SUMMARY of RESULTS

Three of the studies were laser studies, which found that, as compared to Crest White Strips®, the professional laser treatments did not provide a better method for whitening. Whereas a laser can whiten teeth more quickly, it creates heightened sensitivity and, at the end of the treatment cycle, teeth whitened with Crest White Strips® remained white longer than those bleached with a laser.

The other seven studies compared Crest White Strips® to the following products: (1) tray bleaching, (2) a competitor’s bleaching strip, and (3) new versions of the Crest White Strips®. During these studies, subjects were asked to bleach their teeth with the product for varying lengths of time, over a two week period. A computer-based camera was used to measure the color change. In all seven of these studies, Crest White Strips® whitened teeth better than the alternative. Sensitivity, though transient, was present in all whitening systems.

In addition, these ten studies have produced two abstracts in the Journal of Dental Research, two oral presentations, five poster presentations at annual IADR/AADR meetings, and at least one paper that is currently in process.

FUTURE PLANS

Dr. Simon and P&G completed the most recent whitening study in the summer of 2010. The results of that study have been submitted for publication and will be presented in a poster presentation at the International Association for Dental Research in San Diego this March. Dr. Simon and his research team at UTHSC plan to continue to work with P&G on future esthetic dentistry clinical studies. In addition, due in part to the relationship forged by Dr. Simon with P&G, the company has expanded its clinical research scope at UT and plans to test more dental products in the Memphis community. 8

Clinical Research

The following is a list of current clinical research studies being conducted by UT College of Dentistry faculty. The title, investigators, and study objective are listed for each project.

A comparison of the effects of occlusal adjustment and splint therapy on symptoms reduction in TMD Study Objective:

The purpose of this study is to compare the effectiveness of occlusal adjustment and splint therapy on the therapeutic management of temporomandibular dysfunction (TMD).

Principal Investigator:

Dr. Swati Ahuja

Co-Investigators:

Dr. David Cagna and Dr. William McHorris

A Study to Assess the Effects on Plaque Glycolysis and Regrowth Activity of Three Marketed Mouth Rinses Compared to a Negative Control Study Objective:

The study objective is to evaluate the impact of the marketed mouth rinses on the anti-glycolytic activity of dentinal plaque bacteria relative to a negative control.

Principal Investigator:

Dr. Franklin Garcia-Godoy

Co-Investigators:

Dr. Laura Darnell and Dr. Llewellyn Powell

Research Staff:

Laurel Wedel (Research Coordinator) Dr. Yanhui Zhang (Research Associate) and Kimberly DeMonaco (Clinical Research Associate) Dr. Sravanthi Pamarti (Research Volunteer)

Oral Streptococus species in pre-term and full-term 24-36 month old African-American children in Memphis, Tennessee – A crosssectional study Study Objective:

The study objective is to investigate five Streptococcus species commonly found in the oral biofilm of children, specifically Streptococcus mutans, Streptococcus sobrinus, Streptococcus mitis, Streptococcus sanguinis, and Streptococcus salivarius to determine their relative numbers in 24-36 month old healthy African-American pre-term and full-term children residing in Memphis, Tennessee.

Principal Investigators:

Dr. Franklin Garcia-Godoy and Dr. Renalie Rebong

Co-Investigators:

Dr. Jegdish Babu Dr. Alka Cohen

Consultant:

Dr. Reddy Dhanireddy

Research Staff:

Laurel Wedel (Research Coordinator)

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Publications Presentations

The following is a list of publications by College of Dentistry faculty from July 2010 to present, and recent as well as upcoming presentations.

PUBLICATIONS

Ahuja S, Cagna DR. Defining available restorative space for implant dentures. J Prosthet Dent. 2010 Aug; 104(2):133-36. Bumgardner JD, Adatrow P, Haggard WO, Norowski A. Emerging antibacterial biomaterial strategies for the prevention of peri-implant inflammatory diseases. Inter J Oral Maxillo Implants. 2010 Sept. [Epub ahead of print]. Becker W, Cagna DR, Donovan TE, Hilton TJ, Rouse J. Annual Review of selected scientific literature: Report on the Committee on Scientific Investigation of the American Academy of Restorative Dentistry. J Prosthet Dent. 2010 July; 104(1):13-47.

Caplan SA, Levine PJ. Forensic Dentistry Survey. eMedicine from WebMD. http://emedicine.medscape.com/article/1771750overview.

Dabbous MKh, Jefferson MM, Haney L, Thomas EL. Biomarkers of metastatic potential in cultured adenocarcinoma clones. Clin Exp Mestastais. 2010. [In press].

Dabbous MKh, Legan ZT, Tipton DA. Methamphetamine cytotoxicity and effect on LPS-stimulated IL-1beta production by human monocytes. Toxicol In Vitro; 2010 Nov 27 [epub ahead of print].

DiFiore PM, Bowen SE. Cemento-osseous Dysplasia in African-American Men: A Report of Two Clinical Cases. J Tenn Dent Assoc. 2010;90(4):26-28. Souza JG, Bianchini M, Ferreira CF. Relationship between smoking and bleeding on probing. J Oral Implantol. 2010 Aug 6[epub ahead of print].

Garcia-Godoy F, Murray PE. Regenerative Dentistry: Translating Advancements in Basic Science Research to the Dental Practice. J Tenn Dent Assoc. 2010;90(4):12-18. Garcia-Godoy F, Karmer N, Feilzer AJ, Frankenberger R. Long-term degradation of enamel and dentin bonds: 6-year results in vitro vs. in vivo. Dent Mater. 2010 Aug 25 [Epub ahead of print].

Harris EF, Mincer HH, Anderson KM, Senn DR. Age estimation from oral and dental structures. In: Senn DR, Stimson PG, editors: Forensic Dentistry, 2nd ed. CRC Press, Boca Raton, FL, pp. 263-303. Hottel, TL, Antonelli J, Darnell LA. Tensile Bond Strength of Three Dual-Cure Bonding Systems. J Tenn Dent Assoc. 2010;90(4):2023.

Ritts AC, Li H, Yu Q, Zu C, Yao X, Hong L, Wang Y. Dentin surface treatment using a non-thermal argon plasma brush for interfacial bonding improvements in composite restoration. Euro J Oral Sci. 2010 Oct; 118(5):510-6.

Migliorati C, Epstein J, Abt E, Berenson J. Osteonecrosis of the jaw and bisphosphonates in cancer: a narrative review. Nature Reviews Endocrinol. 2010 Nov 16 [Epub ahead of print].

Angel JS, Mincer HH, Chaudhry J, Scarbecz M. Cone-beam computed tomography for analyzing variations in inferior alveolar canal location in adults in relation to age and sex. J Forensic Sci. 2010 Jul 27.[Epub ahead of print].

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Kishan Rao S, Pavicevic Z, Du Z, Kim JG, Fan M, Jiao Y, Rosebush M, Samant S, Gu W, Pfeffer LM, Nosrat CA. Pro-inflammatory genes as biomarkers and therapeutic targets in oral squamous cell carcinoma. J Biol Chem. 2010 Aug 11 [epub ahead of print]. Tipton DA, Seshul BA, Dabbous MKh. Effect of bisphosphonates on human gingival fibroblast production of mediators of osteoclastogenesis: RANKL, osteoprotegerin and interleukin-6. J Periodont Res. 2011 Feb;46(1): 39-47. Versluis A, Tantbirojn D, Lee MS, Tu LS, Delong R. Can hygroscopic expansion compensate polymerization shrinkage? Part I. Deformation of restored teeth. Dent Mater. 2010 Oct 20. [Epub ahead of print]. Da silva NR, Rapos LHA, Versluis A, Fernandes-Neto AJ, Zoares CJ. The effect of post, core, crown types, and ferrule presence on biomechanical behavior of endodontically treated bovine anterior teeth. J Prosthet Dent. 2010 Nov; 104(5):306-17.

PRESENTATIONS Dr. Timothy Hottel (Prosthodontics) has been invited to Las Vegas, Nevada to give a presentation at the International Congress of Oral Implantologists Winter meeting held in February 10-13, 2011.

Dr. Adam Lloyd (Endodontics) has been invited to Lyon, France to give a presentation to the French Society of Endodontics on June 17-19, 2011. Dr. James Simon (Restorative Dentistry) recently presented a poster – titled: Tensile Bond Strength of Ceramic Crowns Using Resin Cement – at the 25th celebration of CEREC, which took place in Las Vegas on August 26th-28th. Dr. Simon presented this poster with two D4 students: Jennifer Hill and Nathaniel Hill. This poster won 1st place at the meeting. Dr. Antheunis Versluis (Bioscience Research) and Dr. Daranee Tantbirojn-Versluis (Restorative Dentistry) will be presenting posters at the IADR meeting in San Diego in March 2011. The titles are - Versluis A, Tantbirojn D, DeLong R. Shrinkage Compensation by Hygroscopic Expansion in Low-Shrink Composite Restorations - Tantbirojn D, Pintado MR, Versluis A, Dunn C, DeLong R. Quantify Tooth Surface Loss Associated with Gatroesophageal Reflux Disease

The following are abstracts that were presented by UT faculty and students at the AADR 2010 meeting: • Simon J, King KA, Powell L, Wilson N, Conde E, Anastasia MK, Carson J, Farrell S. Clinical Comparison of High-Adhesion Whitening Strips and Professional Laser-Assisted Whitening

• • • • • • • • • • • •

Turssi C, Messias D, Hara A, Hughes N, Borges GA, Garcia-Godoy F. Toothpaste Diluent and Dilution Rate Effects on Dentin Abrasion Cohen B, Shiloah J, Ofek I, Babu JP. Effect of Cranberry Juice Constituent on Biofilm on Dental Materials Fagala K, Streight R, Harris E. CBCT Analysis of the Oropharynx: Effcts of Age and Sex

Clark SR, Jefferson MM, Thomas EL, Dabbous MKh. Galectin-1 Levels in Cultured Adenocarcinoma Cells and Conditioned Media Boling J, Adatrow P, Babu JP. LPS Mediated Inhibition of MIP-1 Secretion by Cultured Monocytes Buffington A, Garcia-Godoy A, Garcia-Godoy F, Ferrari M. Flexural Strength of Fiber Posts

Ferrell N, Tipton DA, Rawal S, Dabbous MKh. Effect of Cannabidiol on Gingival Fibroblast MMP Production and Activity Murray PE, Garcia-Godoy F. Human Dental Pulp Biocompatibility Responses to Tissue Engineering Scaffolds Foster C, Harris E. Absence of Continued Dental Eruption in a Modern Adult Cohort

Finder ST, Jefferson MM, Thomas EL. Binding of Epithelial Cell Defensin HBD-3 to Periodontal Pathogen LPS Clark B, Chaudhry J. Retrospective Study of Maxillary Sinuses Utilizing Cone-Beam Computed Tomography Taylor B, Babu JP. Amine Oxide Alteration of Candida Biofilm Resistance to Antifungal Agents Harris E. Tooth Mineralization Standards for American Blacks in the Mid-South

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Grants Sponsorships

The following is a list of current grants/sponsorships held by UT College of Dentistry faculty.

FEDERAL/FOUNDATION GRANTS •

Influence of cranberry juice components on denture related stomatitis and inflammatory reactions of gingival fibroblasts o PI: Jegdish Babu, B.S., M.S., Ph.D. (Bioscience Research) o Co-PI: David Tipton, D.D.S., Ph.D. (Bioscience Research) o Cranberry Institute of Wisconsin (Private Grant)

Biocompatibility screening of restorative treatments o PI: Franklin Garcia-Godoy, D.D.S., M.S. (Sr Exec Assoc Dean for Research/Bioscience Research) o NIH High Priority, Short-Term Project Award (R56)

Hinman Student Research Symposium o PI: Franklin Garcia-Godoy, D.D.S., M.S. (Sr. Exec Assoc Dean for Research/Bioscience Research) o NIH/NIDCR (R13)

Neurotrophin Specificity and Function in the Taste System o PI: Christopher Nosrat, D.D.S., Ph.D. (Bioscience Research) o NIH/NIDCD Research Grant (R01)

Neurotrophin Specificity and Function in the Taste System o PI: Christopher Nosrat, D.D.S., Ph.D. (Bioscience Research) o NIH/NIDCH (ARRA Funding Supplement to R01)

SPONSORSHIPS

Study to assess the effects on plaque glycolysis and regrowth activity of three marketed mouth rinses compared to a negative control o PI: Franklin Garcia-Godoy, D.D.S., M.S. (Bioscience Research) o The Proctor & Gamble Company

Visualization of sealer movement during single-cone obturation with EndoSequence BC Sealer o PI: Adam Lloyd, B.D.S., M.S. (Endodontics) o Real World Endodontics/Brasseler USA

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Awards Honors

Dr. Mustafa Kh. Dabbous (Bioscience Research) was honored at the 16th Hinman Student Research Symposium on October 29, 2010. Dr. Dabbous received a plaque commemorating Dr. Dabbous’s efforts to establish the Hinman Student Research Symposium in 1995 and his continued work to coordinate and host the event. Dr. Dabbous was honored by Dr. Timothy L. Hottel, Dean of the College of Dentistry, and Dr. Franklin Garcia-Godoy, Senior Executive Associate Dean for Research of the College of Dentistry. Dr. Lisa Ku ’10 (former graduate student in the Department of Orthodontics) had her Master’s Thesis featured in the Fall 2010 SAO News, which is the quarterly publication of the Association of Orthodontics. Her committee members were Drs. Edward Harris, Walter Sandusky, and James Vaden. Dr. Ku was awarded the Powell Award for Orthodontic Research at the orthodontics graduation banquet in May. Dr. Ku now resides in Bakersfield, CA where she works in private practice.

Join us for the

16th Annual MidSouth Dental Congress March 4-6, 2011 Hilton Memphis

Get the most “bang for your buck” in Continuing Education Credits while you enjoy presentations on topics you need to improve morale, efficiency, technology, and the bottom line in your dental practice. Friday, March 4th: • Dr. Terry Tankaka: The New Quarterback – A New Treatment Playbook • Dr. Roger Levin: Set Your Practice on Fire! New Strategies for Increasing Production and Creating a Superior pratice • Susan Larson, CDA: Custom Temporaries for Dental Assistants

Saturday, March 5th: • Dr. Jimmy Eubank: Combining Esthetics and Function for Longevity • Dr. John Svirsky: Drugs I have Known and Loved for Diseases that We Catch • Dr. Cesar Migliorati: Current Knowledge of Osteonecrosis of the Oral Cavity • Dr. Franklin Garcia-Godoy: Research Priorities at the College of Dentistry: 2011 and Beyond • Teresa Butler Duncan, RDH, BS: Caries: Evidence-based Prevention and Management Tools for the Future • Caren M. Barnes, RDH, MS: Evolution to Revolution: It’s All About Polishing • Dr. Nancy Williams: Chemical Dependency • Dr. John Svirsky: Great Cases and Diseases • Dr. Ben Johnson: Advancements in Instruments & Irrigation

Sunday, March 6th: • Pamela Ritzline, PT, Ed.D, & Ruth Mulvany, PT, DPT, MS: Managing Postural Pain and Repetitive Stress in Dental Practice • Larry Oxenham: Advanced Lawsuit Protection and Tax Reduction Strategies for Dentists • Dr. Morris Robbins: CPR Certification and Re-Certification Also enjoy UT class reunions, lunches, exhibit booths and mini-sessions, and spouses programs for your significant other. Please visit www.uthsc.edu/midsouthdentalcongress/ or call (865) 974-0280 for updated information and registration. 13

ABOUT the COLLEGE of DENTISTRY The UTHSC College of Dentistry was founded in 1878 making it the oldest dental college in the South, and the third oldest public college of dentistry in the United States.

The College contains a 4-year dental program, totaling approximately 320 students. In addition, students in the Postgraduate dental programs and Dental Hygiene are included.

The College is dedicated to providing professional, graduate, and postgraduate education; conducting dental research; and, delivering state-of-the-art patient care and public service.

College of Dentistry 875 Union Avenue Memphis, TN 38163 Phone: (901) 448-6200 Fax: (901) 448-1625

FOR MORE INFORMATION ABOUT THE UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER, VISIT: www.uthsc.edu

The University of Tennessee is an EEO/AA/Title VI/Title IX/Section 504/ADA/ADEA institution in the provision of its education and employment programs and services.

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Dental Research 1(2) - Winter 2011