The monthly e-newsletter of the nationally ranked University of Toledo College of Pharmacy and Pharmaceutical Sciences
Refill x
AUGUST 2014
HOME away AWAY FROM HOME : from home Welcoming and retaining international graduate students GINKGO AND STROKE The popular supplement is showing promise in the field of stroke recovery, as studied by Dr. Zahoor Shah.
PG2 LEADERSHIP LESSONS As Dr. Paul Erhardt celebrates 20 years of leading the CD3, he reflects on what has made him successful.
PG3
Having left the comforts of the United States
Graduate
to explore graduate education abroad, Dr.
Retention, Dr. Bryant-Friedrich is a valuable
Amanda
resource to graduate students experiencing
Bryant-Friedrich
knowledge
of
The annual event introduces high school students to a career path and a source of inspiration.
PG4 INTERNATIONAL APPE An alumnus shares his experience of completing an Advance Pharmacy Practice Experience in China.
PG4
complex
firsthand transition
Recruitment
and
the United States, often for the first time.
awaiting graduate students who come to the
“Students who decide to pursue advanced
College of Pharmacy and Pharmaceutical
degrees outside their country of origin are
Sciences from around the globe. Completing her doctorate
PHARMACY CAMP
the
has
Student
in
NEW INTERNATIONAL GRADUATE STUDENTS IN THE COLLEGE
Heidelberg,
20
20
19
19
often faced with barriers of immigration and matriculation that originate
Germany and postdoctoral
from a lack of knowledge
training in Basel, Switzerland
from the perspectives of both
allowed
her
academically
to
and
grow see
2011
the
2012
2013
2014
the
stude nt
respective
and
the
institution
of
world, but these experiences were often
higher learning,� Dr. Bryant-Friedrich said.
challenging;
and
As the College engages new regions of the
the
world to attract graduate students, Dr.
community
missing at
times
her
home
compounded
challenges. In her new role as Director of International
Pharmaceutical
Sciences
Bryant-Friedrich
plans
to
introduce
(Continued on page 4)
“Research is formalized curiosity. It is poking and prying with a purpose.” Zora Neale Hurston author and anthropologist
CD3 ANNIVERSARY SYMPOSIUM
Ginkgo biloba
ENHANCES STROKE RECO
STROKE IN AMERICA The Center for Drug Design and Development celebrated 20 years under the leadership of Distinguished University Professor Paul W. Erhardt with a research symposium that welcomed prominent researchers, professor emeriti, alumni and scholars.
Stroke is the fourth leading cause of death and a major cause of long-term disability, which inflicts substantial economic and societal burdens. Drug therapies aimed at post-stroke recovery that can enhance a person‟s own ability
The plenary lecture, by Dr. Gunda Georg, explored “Drug Discovery in Academia: Minnelide for Pancreatic Cancer and Gamendazole for Male Contraception.” Dr, Georg is head of medicinal chemistry at University of Minnesota and the director of the Institute for Therapeutics Discovery & Development.
to replenish injured or dead brain cells
The ke ynote spe a ke r w a s D r. Christopher A. Lipinski, a pha rm ace u t ica l co ns ul ta nt a n d contractor who is best known for his "Rule of Five," the most frequently cited medicinal chemistry publication of the last decade. Dr. Lipinski discussed the direction of drug discovery.
neurogenesis-enhancing properties that
The dinner lecture on “Fascinating Excursions into Chiral Chemistry: An Insider‟s Perspective” was presented by Dr. Mukund Chorghade, Chief Scientific Officer at THINQ Pharma. Dr. Chorghade, an adjunct faculty member at Cal Tech, Harvard, MIT and Cambridge Universities, has published hundreds of articles and has received three “Scientist of the Year” awards.
with new developing brain cells (endogenous neurogenesis) may help minimize the cost related to prolonged hospital stays and rehabilitation. Ginkgo biloba, a widely studied herbal product for the treatment of neurological disorders,
offers
endogenous
hold the promise of providing recoveryimproving benefits to stroke patients. EFFECTS OF GINKGO BILOBA Led by Dr. Zahoor A. Shah, Dr. Shadia E. Nada and graduate student Jatin
Tulsulkar, researchers in the College of Pharmacy and Pharmaceutical Sciences have discovered that mice treated with Ginkgo biloba 4 hours after inducing an experimental stroke, and then daily for seven days, had improved recovery and less brain damage than the control mice. It was also observed that Ginkgo bilobatreated
mice
had
enhanced
neurogenesis, partly due to the increased protein expression of hemeoxygenase 1, an antioxidant gene that also has a role in neurogenesis. Pertinently, mice lacking the hemeoxygenase 1 gene were observed to have reduced neurogenesis after stroke. An important finding was that in Ginkgo biloba-treated mice the majority of these new cells were found in the proximity of the stroke injury site, suggesting their role in repairing the injured/dead neurons. Besides prevention, improving recovery following a stroke should become the
USING REWARDS TO TREAT SUBSTANCE ABUSE In 2008, the National Survey on Drug Use and Health (NSDUH) estimated that 1.9 million Americans were current cocaine users, with the majority falling between the ages of 18 and 25.
Cocaine‟s physiological and psychological effects include cardiac disturbances, strokes and seizures, and psychosis, making treatment for cocaine addiction a serious public health concern.
Dr. Caren Steinmiller, who earned he B.S. in „93 and her M.S. in „95 from The
LOREM DOLORE
SIT ALIQUAM ABOUT GINKGO BILOBA
One of the world‟s oldest living species of trees, the ginkgo tree can grow up ASSET LIABILITY AND RESTRUCTURING to 120 feet tall and live for up to 1,000 years. Ginkgo biloba has been used for ipsum dolor sit amet, consectetuer adipiscing elit sed 23% purposes for thousands ofQuorem medicinal years to treat a broad range of disorders, diam nonum my nibh euismod tincidunt utte laoreet do lore from memory loss to circulatory disorders. The Ginkgo biloba‟s magna aliquam erat research volutpat utte on wisi enim ad minim veniam use for the treatment of Alzheimer‟s disease and stroke is a budding area of tincidunt ut laoreet dolore magna aliquam. excitement among researchers. 68% People who take Ginkgo biloba supplements should9%take note of the potential drug EUSIMOND interactions andWISI safety LOREM IPSUM TINCIDUNT recommendations.
d c d e h
r e
On the occasion of his twentieth anniversary of leading the Center for Drug Design and Development, Distinguished University Professor Paul W. Erhardt looks back.
1
OVERY prime focus of current stroke research. We now know that neurogenesis is not only an ongoing process in adults, but can also be induced by pathological conditions like traumatic brain injury and ischemic stroke, and strategies that promote endogenous neurogenesis as part of the repair and regeneration process
LEADERSHIP LESSONS
should
be
prioritize d.
Neurogenesis in the adult brain involves not only the proliferation and migration
THE EFFECTS OF TIME “Has it really been that long? Time flies when you‟re having fun.”
regeneration. The study, first reported in Molecular Neurobiology (Vol. 49, 2014) and then reviewed in Neural Regeneration Research (Vol. 9, 2014), confirmed that Ginkgo biloba, in addition to its antioxidant, neuritogenic and angiogenic properties, provides a conducive environment for the survival and functional integration of NSCs into neural system.
of precursor cells known as stem cells/
“Controversies and other ethical issues
neural progenitor cells (NSCs) but also
related to stem cell therapies make drug
their functional integration into the
induced, enhanced neurogenesis a
neural network. Though ischemia is
promising treatment strategy,” stressed
potent in inducing the proliferation and
senior author Zahoor A. Shah. “Besides
migration of NSCs, it does not provide
one
an environment conducive to their
recommending the use of Ginkgo biloba
survival, differentiation and integration,
after ischemic stroke, further high
and creating an environment with
quality and large-scale randomized
exogenous drugs is paramount to
controlled trials are warranted to test
improving the number of NSCs that can
its efficacy in stroke recovery” he said.
doc u me nte d
cl in i cal
tr ia l
result in improved brain repair and
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2 AFFETTUOSO “I have an all-encompassing fascination for the science of medicinal chemistry, a science where the intriguing relationships between its beautiful chemical structures and their biological properties are oftentimes applicable toward potentially alleviating some health issue being experienced by people less fortunate than I.”
3 TEAMING UP “Addressing technical problems in a teamwork fashion, CD3‟s constituencies have always been supportive and have rallied to get the job done. Our numbers of patents, papers and graduate thesis documents provide solid testimonials to that, and we can all be very proud for such accomplishments.”
4 FOR AND BY THE PEOPLE “It has been, and will always be, CD3‟s people that make the CD3 so very special in its productivity and fun. The camaraderie established when tackling this complex field has brought us together like a close-knit family, vibrant with each generation of new student members arriving as our matured graduates depart.”
AROUND THE WORLD AND BACK AGAIN SMOOTH SAILING DR. AMANDA BRYANT-FRIEDRICH IN 1997 ON THE DAY THROUGH STRATEGIC SHE COMPLETED HER DOCTORATE FROM RUPRECHT BUSINESS DECISIONS KARLS UNIVERSITÄT IN HEIDELBERG, GERMANY
pharmacy camp
INSPIRES FUTURE ROCKET SCIENTISTS
Each summer, the college welcomes two cohorts of 40 rising high school seniors to Pharmacy Camp, a four-day experience sponsored by Walgreens, that introduces prospective students to pharmacy in a hands-on format. Campers shadowed Toledo pharmacists, visited the Toledo Zoo where they learned about veterinary pharmacy from alumnus Matt Buderer, and made some great friendships with other campers. Proudly sporting their “future Rocket scientist” gear, many of this summer‟s pharmacy campers hope to be part of next fall‟s freshman class. Galvanizing students to explore careers as pharmacists and pharmaceutical scientists is the primary goal of Pharmacy Camp. One camper said, “I can't thank The University of Toledo enough for giving me such an amazing opportunity and experience of a lifetime. I've never been more positive and sure about anything like I now am about attending this school and pursuing pharmacy as my future career.”
HOME AWAY FROM HOME
continued from page 1
members of the college community to
with a common interest in international
the educational systems, culture and
relationships,” Dr. Bryant-Friedrich said.
research enterprise in each region. Her
The college is continually increasing the
new role also requires a heightened
population of graduate students who are
sense of awareness of the political and
well prepared academically for
economic conditions of the countries
coursework and research. Dr. Bryant-
from which international learners
Friedrich sees this as an opportunity to
originate to make sure that students
create recruitment pipelines from
receive counseling and support to help
prestigious institutions abroad.
them maintain an exceptional level of academic performance, even when thoughts of home are a distraction. Another
feels fortunate for the opportunity to ease the transition for graduate students
international students is ensuring their
in the College of Pharmacy and
sense of community upon their arrival.
Pharmaceutical Sciences.
“I
strong
“The global scientific community relies
relationships with community-based
on the establishment of productive
organizations that have ties and services
collaborations based on mutual trust
important to the needs of our
and understanding,” Dr. Bryant-
international students. This will include
Friedrich said.
working with the UT Center for
improve the human condition than to
International Students and Programs as
bring brilliant students from around the
well
world together to improve what really
as
to
of
17 graduate students from 11 countries,
retaining
intend
aspect
Dr. Bryant-Friedrich, who has mentored
m a i n t a in
Toledo
Sister
Cities
International and other organizations
INTERNATIONAL APPE: A STUDENT’S JOURNEY By CHUN WONG, PharmD ‘14 As a P4 student pharmacist, I began my Advance Pharmacy Practice Experiences (APPEs) in a unique way. My first APPE
“What better way to
matters.” rotation was at the Affiliated Hospital of North Sichuan Medical College located in Nanchong, the second most populated city of Sichuan Province, China. Over the course of a month, I worked with my preceptors to learn about traditional Chinese medicine (TCM), including acupuncture and herbal
Save the date: 09.06.14 at 10 a.m. ROCKETS V. MISSOURI TAILGATE Network with alumni, faculty, students and friends of the College of Pharmacy and Pharmaceutical Sciences at the Pillbox tailgate tent, sponsored by Giant Eagle. Bring your business cards!
ABRINDO AS PORTAS OPENING OUR DOORS This fall, the College of Pharmacy and Pharmaceutical Sciences welcomes eight learners from Brazil to take bachelor‟s level pharmaceutical science courses at The University of Toledo as part of the Brazil Scientific Mobility Program (BSMP).
allows Brazilian students to study in some of the world‟s most prominent institutions. The students, who are nominated and supported by their home universities, will take courses and conduct research in cosmetic science and formulation, pharmaceutics, medicinal chemistry and pharmacology. The BSMP program is sponsored by the Brazilian Ministry of Education and the Brazilian Ministry of Science and Technology.
The one-year, non-degree program
COMMUNITY EDUCATION P4 student Elias Bassil, an officer in the UT chapter of Student National Pharmaceutical Association, spoke at the Career Pathways Center of the Norman and Louise Jones Foundation to educate young adults about the adverse effects of illegal drugs. Because of the success of his presentation, the foundation‟s executive director invited Elias begin a weekly series of presentations to discuss topics in pharmacy, careers, and education for young adults and their families.
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KUDOS: STUDENT RESEARCH AND AWARDS
1 WALMART SCHOLARS AT AACP Pharmacy students Kimberly Zitko and Philip King were selected to participate in the 2014 Wal-Mart Scholars program with their respective faculty mentors, Dr. Michelle Serres and Dr. Michael Peeters. Their $1000 scholarships funded their attendance at the American Association of Colleges of Pharmacy (AACP) Annual Meeting and Teachers‟ Seminar.
2 GRADUATE RESEARCH AWARD Kush Patel, a graduate student mentored by Pharmaceutics Associate Professor Dr. Jerry Nesamony, earned a Graduate Student Award from the College of Graduate Studies for the Graduate Student Association (GSA). The award of $1893 will fund his research on “An Insulin Oral Drug Delivery via Calcium Alginate Nanoparticles”.
3 OFFICIAL RECOGNITION UT‟s chapter of the Student Society of Health-system Pharmacists has been officially recognized by the national parent organization, the American Society of Health-System Pharmacists.
“I have been impressed with the urgency of doing. Knowing is not enough; we must apply. Being willing is not enough; we must do.” Leonardo da Vinci artist, inventor, original Renaissance man
CALENDAR OF EVENTS 08.15.14 Beginning of smoke-free campuses at UT 08.22.14 Professional Advancement Ceremony, Nitschke Auditorium, 4pm 08.25.14 Fall 2014 classes begin. 09.04.14 Dean‟s Commission on Pharmacy Education, two-day semiannual meeting 09.06.14 Pill Box tailgate tent sponsored by Giant Eagle for Rockets v. Missouri, 10am.
TRADITION, ETHICS and the PROFESSIONAL ADVANCEMENT CEREMONY White Coat Ceremonies occur at medical and pharmacy schools across the nation, but what do they really symbolize, and how is our ceremony different from many others? The Professional Advancement Ceremony held by the college each year to welcome P1 students into the professional division has its roots in the tradition of White Coat Ce r e mo n ie s, r i tua l “ r ob i n g” ceremonies for physicians and other health care professionals.
10.04.14 Annual Wal-Mart Student Leadership Retreat
Traditionally, such ceremonies include oaths of commitment to the ethical and professional standards for the profession. The white coat symbolizes the honor bestowed by society upon health care and laboratory professionals, and the ceremony welcomes initiates in these professions to the early stages of their professional development.
10.24.14 Pre-gala reception in Student Union room 2592, class reunion, Homecoming Gala in the Student Union Auditorium, and postGala gathering in Student Union room 2592
get the picture
09.10.14 Infectious Disease Update Registration due by 09.04.14 Download printable brochure
10.25.14 Homecoming parade 10am, alumni tailgate 12pm, Rockets v. UMass at 2pm
11.12.2014 Pharmaceutical Sciences Board, twoday annual meeting
At The University of Toledo, the Professional Advancement Ceremony has evolved uniquely to include the “robing” of both students in the Doctor of Pharmacy program a n d t ho se i n th e B .S . i n Pharmaceutical Sciences program‟s cosmetic science and formulation design, medicinal and biological chemistry, pharmaceutics, and pharmacology/toxicology majors. Students who major in pharmacy administration are honored with a professional portfolio, symbolic of their use of data and management in pharmacy. All students touch the lives of others, either through patient care, management or research, thus the emphasis on standards of behavior and professionalism benefits the new P1 students. Their understanding of the rewards and responsibilities of their chosen careers is an essential brick in the foundation of professionalism.
Click the links for photos of recent college events.
CD3 Symposium
Mid-Atlantic Graduate Student Symposium in Medicinal Chemistry
Homecoming 2014
Class Reunions Pre-Gala Reception Homecoming Gala Post-Gala Gathering Homecoming Parade Alumni Tailgate Rockets vs. UMass
Join The University of Toledo College of Pharmacy and Pharmaceutical Sciences as we celebrate Homecoming and the 110th anniversary of the college.
Pre-Gala Reception, reunion Student Union Room 2592 Cash bar, hors d'oeuvres
Annual Edward C. Schmakel Homecoming Parade Bancroft Street
Gala banquet ($30) Pharmacy honoree is Jerry Wisler, ‘79. Student Union Auditorium
Pre-game tailgate Koester Alumni Pavilion
Post-Gala Gathering Student Union Room 2592
This year’s Homecoming theme is Blast from the Past. Do you remember when Rocky looked like this?
Rockets vs. UMass ($25) Glass Bowl Stadium
www.utoledo.edu/pharmacy/alumni Jeff Barton, 419-530-5413 or Jeffrey.barton@utoledo.edu Ashleigh Sonnenberg, 419-530-5359