Synapse (04.17.14)

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MIND&BODY

FOOD

Top 10 Scariest Things I See at the Gym » PAGE 7

Battle of the Ice Cream Sandwich » PAGE 9

Let's Get Physical...

Dreams vs. CREAM

IN THIS ISSUE

News Briefs » PAGE 3 Grad School Illustrated » PAGE 7 Puzzles » PAGE 11

Synapse The UCSF Student Newspaper

Thursday, April 17, 2014

NEWS

synapse.ucsf.edu

Volume 58, Number 27

NEWS

Open Access The CSI Effect: Science ‘As Seen on TV’ Inspires New Publishing W Models By Nicole Croom Staff Writer

This series explores the impact of open access journals on the scientific publishing industry. In this final installment, we look at how the industry's shifting fee structure is hurting scientists. We also explore the rise of alternative publishing models.

PART 3 By Alexandra Greer Science Editor

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any scientists make the assumption that open access journals are non-profit entities because of their “open” nature and the fact that they do not charge subscription fees. In fact, few open access journals are truly non-profit organizations; many are simply companies generating revenue using a different business model. Whereas closed access journals make a majority of their money through subscription fees, open access journals must find revenue elsewhere. By far, the most recognizable model is to charge authors “article processing fees,” or APCs, to cover the costs associated with online publication. In the span of a few years, open access journals have altered the scientific publishing landscape, making it cheaper and easier for researchers to access published research. But in doing so open access journals have shifted the cost of publication from the reader (or university library) to the scientist-author. “To be self-sufficient, you have to have a way of generating income, and page charges are one of the ways,” said Dr. Alexander Johnson, professor of Microbiology and Immunology and Biochemistry and Biophysics at UCSF. “Someone has to pay for it.” With research funds increasingly difficult for new investigators to secure, every dollar is precious. And for investigators trying to make a name for themselves in the scientific world, publications are the primary form of currency. Despite the surging popularity of the open access movement, the increasingly popular APC business model may not be sustainable for penny-pinching scientists in times of dwindling lab funds.

OPEN ACCESS » PAGE 4

hen was the last time you were sitting down after a hard day’s work, unwinding with your favorite TV crime drama and you thought to yourself, “Really? They caught the guy because they found a leg from the Rubarura bug on the hem of the victim’s left pant leg and the killer just happens to live on the only street in the world that particularly bug inhabits? Uh huh, riiiiight.” Which begs the question: how accurate are crime shows and do their inaccuracies have any effect on the real world, a so-called “CSI effect”? Dr. Judy Melinek, a medical examiner and Assistant Clinical Professor of Pathology at the UCSF Medical Center, sat down with me to try and shed light on the topic. She recently posted an article, “7 CSI Fails,” on her Pathology Expert blog that goes into further detail about the errors television crime shows consistently make. The “CSI effect” is a term that was first coined by prosecutors to describe their perceived drop in conviction rates due to jurors’ hesitancy to give a guilty verdict if a case is lacking in forensic evidence. Prosecutors attributed the drop to the portrayal of how important forensic findings are in crime shows, like CSI and Bones. No studies have supported the claim that such a decline in conviction rates exists, but

Photo courtesy of CBS Are jurors' attitudes about forensic evidence influenced by watching too many TV crime dramas?

Melinek does write that, “As an expert witness in forensic pathology, I see the CSI effect when I'm faced with questions like, ‘Why can't you tell us the precise time of death down to the minute, like on TV?’” Forensic pathology isn’t the only medical field that is portrayed imprecisely. Melinek has also consulted for TV shows such as ER, and though she said that the produc-

ers take your advice into consideration, such as her consultation on the scene about how a patient’s make-up should be redone, unfortunately, “They often get the details right, but they get the sequence wrong.” Many medical and medico-legal shows also utilize technology far beyond what is used today—call it creative license. TV inves-

THE CSI EFFECT » PAGE 3

NEWS

UCSF Team Wins AMCP P&T Competition By Linda Chen Staff Writer

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Photo by Michelle Nguyen/P2 UCSF School of Pharmacy representatives at the AMCP P&T Competition in Tampa, Fla.

t was all sunshine and smiles in Tampa, Florida for the UCSF Pharmacy and Therapeutics (P&T) team as they took home first place in the 14th Annual AMCP P&T Competition on April 4. The team, consisting of Edna Cheung (P1), Randal Du (P3), Isabel Fong (P1) and Thomas Lee (P2), accepted the honor and $2500 scholarship with faculty advisor, Glen Yokoyama before the cheers, roar, and tears of their UCSF family. The prize money will be contributed to the school’s general scholarship fund. The celebration quickly spread to UCSF after Dean Joseph Guglielmo, who had given the team a pre-competition pep talk via phone, proudly shared the achievement with

P&T COMPETITION » PAGE 7


2 | April 17, 2014 | synapse.ucsf.edu

EVENTS MISSION BAY EVENTS FOOD TRUCK THURSDAYS AT MISSION BAY

Thursday, April 17, 11 a.m.-2 p.m., 4th Street & Nelson Rising Lane, Mission Bay
 Join the food truck lunch party every Thursday at Mission Bay and explore the tasty culinary options to break up your routine. Each week will feature two different vendors, so there will always be something new. Grab some friends, get some food, and take your lunch experience up a notch.

SYNAPSE NEWSPAPER

Friday, April 18, noon-1 p.m., Graduate Division, CC-310, Mission Bay Synapse is looking for Mission Bay and Parnassus writers, bloggers, photographers and designers. Come to the lunch meeting, share your story ideas and enjoy a free lunch. RSVP to Steven Chin, synapse@ucsf.edu.

MUSLIM FRIDAY PRAYER SERVICES

Friday, April 18, 1-2:30 p.m., Helen Diller, 160, Mission Bay
 The Muslim Community at UCSF holds regular Friday prayer services (Jum’a) for the UCSF Muslim community every week. Come join your fellow brothers and sisters for prayer, lunch and socializing. All are welcome.

MISSION BAY RIPS

Friday, April 18, 4-5 p.m., Genentech Hall Auditorium, Mission Bay Research In Progress Seminar is a seminar series at which one student and one postdoc present their current research. Talks are 15 minutes in length and are preceded by a 20-minute social. Snacks and beverages are provided.

MISSION BAY FARMERS’ MARKET

Wednesday, April 23, 10 a.m.-2 p.m., Gene Friend Way Plaza, Mission Bay Shop healthy, shop fresh, shop Californiagrown at the UCSF Farmers' Market, every Wednesday (rain or shine). Sponsor: Pacific Coast Farmers' Market Association.

PARNASSUS EVENTS EXPERIMENTAL DANCE THEATRE WORKSHOP

Thursday, April 17, 8:30-9:30 p.m., Millberry Fitness Center, Studio 2, Parnassus Come dance with us! One of our members will be leading an all-levels *ballet* workshop!

NAHA SPRING CULTURAL EVENT

Friday, April 18, 11 a.m.-2 p.m., Saunders Court, Parnassus The Native American Health Alliance (NAHA) Spring Cultural Event brings together Native American drummers and dancers of various tribal origins to perform on the UCSF Parnassus Campus. Visitors are welcome. Traditional fry bread and Indian tacos are served for all attendees.

MUSLIM FRIDAY PRAYER SERVICES

Friday, April 18, 1:30-2 p.m., Medical Sciences, 178, Parnassus The Muslim Community at UCSF holds regular Friday prayer services (Jum’a) for the UCSF Muslim community every week. Come join your fellow brothers and sisters for prayer, lunch and socializing. All are welcome.

ANNUAL KOREAN CULTURE SHOW

Friday, April 18, 4-9 p.m., Cole Hall, Parnassus The annual Korean Culture show which will be comprised of series of performance. The performances would be from traditional fan dance, musical ensembles, martial arts to contemporary music and K-pop!. This event is to enrich the awareness of Korean pop culture to public.

CAMPUS EVANGELISTIC FELLOWSHIP

Friday, April 18, 7-10:30 p.m., Nursing, 517, Parnassus Join the Campus Evangelistic Fellowship for its weekly meeting, with Bible study, hymn singing and fellowship.

INTEGRATIVE MEDICINE FOR THE FUTURE

Saturday, April 19, 8 a.m.-4:30 p.m., Cole Hall, Parnassus The Integrative Medicine Forum will feature speakers and workshops on a variety of topics related to contemporary and future use of complementary and alternative medicine practices in modern healthcare. UCSF students may receive one unit of elective credit for the Spring 2014 term by enrolling in FCM 171.04 and by purchasing an eventbrite ticket. eventbrite.com/e/ucsfforum-integrative-medicine-for-the-futuretickets-10512375799.

EXPERIMENTAL DANCE THEATRE WORKSHOP

Sunday, April 20, 6-7 p.m., Millberry Fitness Center, Studio 2, Parnassus Come dance with us! One of our members will be leading an hour long, all levels *Musical Jazz Theatre* dance workshop! No experience necessary.

PRECISION MEDICINE DISCUSSIONS

Monday, April 21, noon-1 p.m., Health Sciences West, 302, Parnassus The newly formed Precision Medicine Student Alliance (PMSA) is searching for motivated students to join its leadership and help form a successful culture. There are many positions available, and time commitments are minimal. Students from all disciplines and programs are encouraged to apply! PMSA is an interprofessional organization that aims to promote awareness about precision medicine across UCSF.

PARNASSUS FARMERS’ MARKET

Wednesday, April 23, 10 a.m.-3 p.m., ACC, 400 Parnassus Ave.
 Shop the Farmers’ Markets on Wednesdays to pick up locally grown produce and more. Sponsor: Pacific Coast Farmers’ Market Association.

SYNAPSE NEWSPAPER

Wednesday, April 23, noon-1 p.m., Millberry Union 123W, Parnassus Synapse is looking for Mission Bay and Parnassus writers, bloggers, photographers and designers. Come to the lunch meeting, share your story ideas and enjoy a free lunch. Email synapse@ucsf.edu to RSVP.

UCSF RUN CLUB

Wednesday, April 23, 5:30-6:30 p.m., Millberry Union Central Desk, Parnassus Please drop by and join UCSF Fit & Rec for a run. Each Wednesday night, the Run Club runs various distances (from 3-6 miles) at 9 to 11 minutes per mile.

ENGLISH CORNER

Wednesday, April 23, 6-8:30 p.m., Clinical Sciences, 130, Parnassus English Corner is an informal conversational English class given as a free community service and provided on a voluntary basis by both people born and raised in the United States as well as many people who have, at one time in their lives, experienced life as a new immigrant to the United States.

VIETNAMESE STUDENT ASSOCIATION ANNUAL SPRING CULTURE SHOW

Wednesday, April 23, 6-8 p.m., Cole Hall, Parnassus The Vietnamese Student Association would like to invite all UCSF students, faculty and staff to the Annual VSA Spring Culture Show. Enjoy free authentic Vietnamese food along while being immersed in a performance showcasing the three beautiful regions of Vietnam. Please join us for a night of food, fun and cultural dances!

OFF-CAMPUS OFF THE GRID: UPPER HAIGHT

Thursday, April 17, 5-9 p.m., Stanyan and Waller Streets, SF Off the Grid is a roaming mobile food extravaganza that travels to different locations daily to serve delicious food, with a free side of amazing music, craft and soul.

CALIFORNIA ACADEMY OF SCIENCES: DANCE PARTY NIGHTLIFE

Thursday, April 17, 6-10 p.m., Cal Academy, Golden Gate Park Shake, shimmy, twist and twerk your way into NightLife’s first ever museum-wide dance party. Whether you’ve got two left feet or can cut a rug with the best of them, NightLife invites you to try out popular dance styles from around the world. http://bit.ly/ NightLifeTickets, http://bit.ly/CLSDiscounts.

EXPLORATORIUM: AFTER DARK

Thursday, April 17, 6-10 p.m., Pier 15, SF Experience some of the fascinating and beautiful technologies that help us transcend our physical limitations. Featuring exoskeletons, wearable computers, 3D-printed prosthetics, electronically enhanced couture and more. exploratorium. edu/visit/calendar/after-dark.

EXTRAVAGANZA

Saturday, April 19, 11 a.m., Sharon Meadows, SF The Annual Eggstravaganza in Golden Gate Park’s Sharon Meadow will include egg hunts, arts and crafts, carnival rides and more!

SPRING CELEBRATION & EASTER PARADE

TABULA THE SYNAPSE LITERARY ISSUE IS COMING APRIL 24! Submit poems, short stories and photos with captions to Synapse by APRIL 20. synapse@ucsf.edu.

BAPHON BLOOD DRIVE

Wednesday, April 23, 11 a.m.-3 p.m., In front of Millberry Union, Parnassus Schedule your life-saving appointment by visiting the Blood Centers of the Pacific website and clicking on Donate Blood. This event is sponsored by BAPHON (Bay Area Pediatric Hematology/Oncology Nurses). All donors will receive 1000 bonus hero points, which can be redeemed online for a pair of movie tickets or other awards! Please be sure to eat a good meal before donating, drink plenty of water, and bring identification. To schedule your life-saving appointment, please visit www.bloodheroes.com. Enter sponsor code: BAPHON.

UCSF LIVINGGREEN FAIR: VOLUNTEERS NEEDED – RSVP APRIL 20

Thursday, May 8, 10 a.m.–2 p.m, Millberry Union Conference Center, Parnassus UCSF LivingGreen is seeking volunteers to assist on the day of the fair for one hour. Volunteers will recieve a light lunch, tasks include greeting attendees, check-in table, delivering lunch to vendors and more. Please send an e-mail for a list of the tasks and time to kathryn.hyde@ucsf.edu. Please send by April 24.

NOMINATE A SUSTAINABILITY CHAMPION FOR UCSF SUSTAINABILITY AWARDS: DEADLINE APRIL 25

Nominate a deserving champion of sustainability in you midst. Do you know a faculty, staff, student or a team who consciously models sustainable behavior and influences others to do the same? Nominate them! http://sustainability.ucsf.edu/1.128.

ARE YOU A FIRST GENERATION TO COLLEGE STUDENT (FG2C)?

Register with the First Generation Support Services Office, for access to all of the First Generation Support Services and to help the office advocate for you. Register before April 15 to be entered to win one of three giveaways! bit.ly/firstgenregister.

Sunday, April 20, 10 a.m.–5 p.m., Union Street, SF This is definitely not your average formal Parade, with everything from roller-blading cows and creative self-propelled mini-floats to garden areas, sophisticated fashions and beautiful classic cars. sresproductions.com/ union_street_easter.html.

FG2C BROWN BAG MENTORING

ANNOUNCEMENTS

FREE SYNAPSE CLASSIFIEDS

APPLY TO BE A UCSA STUDENT REP: DEADLINE APRIL 29

The University of California Student Association (UCSA) is recruiting for UC System-wide Committee Student Representatives, Student Observers to select Regent Committees and Collective Bargaining Program Representatives. Join thousands of other UC voices fighting for the quality, accessibility and affordability of the UC system. Apply today: http://ucsa.org/getinvolved/

This Brown Bag Mentoring program is designed to help UCSF first generation college students connect with first gen faculty, postdocs, residents, fellows and alumni who have generously offered to meet with you over lunch. Sign up at bit.ly/brownbagmentor.

UCSF students and staff can now post online classified ads for free on the Synapse website. All you need is an @ucsf.edu email account. Try it out! synapse.ucsf.edu/classifieds.

WALK WHILE YOU WORK IN THE PARNASSUS LIBRARY

The Parnassus Library has installed two new Walkstations so that you can walk while you work on a computer on the second floor of the Technology Commons. The library also has more height-adjustable workstations. library.ucsf.edu/content/new-walkstationsavailable-library-tech-commons.


synapse.ucsf.edu | April 17, 2014 | 3

NEWS

Paying it Forward: Dental Students Travel to California Care Force Clinic

Photo by Jean Calvo/D2 Back row: Sim Kim and Tim Wen, Middle Row: Rose Oji Osidana and Marilyn Nguyen, Front row Randy Rosales and Angeline Salvani. All are second-year dental students.

By Jean Calvo Contributing Writer

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alifornia Public Health Association at UCSF organized a group of nine dental students to volunteer at the California Care Force Clinic in Indio, Calif. earlier this month. Niloo Farhani (D3), Jean Calvo (D2), Sam Kim (D2), Randy Rosales (D2), Tim Wen (D2), Marilyn Nguyen (D2), Angeline Salvani (D2), Rose Odsinada Oji (D2), and Christina Chen (D1) traveled to Indio late Friday night and volunteered assisting with dental procedures from 6 a.m. to 5 p.m. on Saturday and Sunday, April 3-6. The California Care Force clinic provided a huge underserved population with access to dental, medical and vision services over the four-day clinic. With the help of volunteers like students from UCSF the clinic was able to provide a total of $907,447 worth of services at zero cost to patients. UCSF students had a very rewarding and exciting experience volunteering. Patients were extremely grateful to receive the treatment they desperately needed.

“It was a really awesome time, I definitely want to volunteer again next year,” said Sam Kim. California Public Health Association is grateful to the generous donors who helped to cover the cost of travel. California Care Force organizes free mobile medical clinics to provide communities short term medical, dental and vision care. California Care Force uses a community center, school or some other public space to setup dental stations, eye exam stations and medical care stations and provide patients with free services including making eye glasses on site. The clinics are operated by volunteer professionals taking time from their practices to give back to the community. The goal of the organization is to be able to move from community to community to provide this urgent care at least once a month. To do this it needs to raise the funds to purchase more equipment and supplies. If you are able to volunteer at a clinic or are in a position to make a donation your help is very much appreciated. Visit the website at www.californiacareforce.org.

Jean Calvo is a second-year dental student.

Synapse

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About

Synapse is the UCSF student-run weekly newspaper, which runs on Thursdays during the academic year and monthly during the summer. Synapse seeks to serve as a forum for the campus community. Articles and columns represent the views of the authors and not necessarily those of the Board of Publications or the University of California.

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Announcements and letters should be submitted six days before publication. All submissions can be either emailed or mailed. All material is subject to editing. Letters to the Editor must be signed by the author.

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Paid advertisements do not necessarily reflect the views of Synapse. Synapse and its editorial board reserve the right to decline advertisements promoting false or misleading claims, known health risks, or content deemed by the editors to be antithetical to the interests of UCSF students or the UCSF community. Synapse does not accept advertisements from tobacco or alcohol manufacturers, or sexually oriented personal ads. Synapse reserves the right to run any ad with a disclaimer.

The CSI Effect » FROM HOME PAGE

tigators receive DNA and lab results within hours, when in reality such things take weeks to months to run. An official autopsy report, complete with toxicology and histology, takes months to complete. Melinek also discussed whether crime shows can help criminals learn how to cover up their crimes and if it’s true that in order to work closely with the deceased you must be more detached than most people. While it’s true that there has been at least one example of a serial killer planning out his crimes based on what he learned from television shows, “very few people are sociopaths,” said Melinek. “They end up giving themselves away in other ways.” And, in fact, the aforementioned killer, Cary Stayner (The Yosemite Killer), was caught due to several rectifiable oversights. Citing the forensic anthropologist Dr. Temperance Brennan from Bones as a prime example of the misconception that the best forensic investigators are somewhat antisocial, Melinek emphasizes that, “empathy is important… having empathy doesn’t mean you can’t be objective.” “If you can’t communicate, you’re not doing your job either,” she added.

NEWS BRIEFS

Four Receive UCSF Medal for 'Advancing Health Worldwide'

UCSF Interim Chancellor Sam Hawgood, MBBS, bestowed the UCSF Medal to four leaders for outstanding contributions in areas associated with UCSF’s mission to "advance health worldwide" at the 2014 Founders Day banquet. The celebration occured at the UCSF Mission Bay campus on the evening of April 10. The recipients of the 2014 UCSF Medal are: • Carroll L. Estes, PhD – founder and former director of the UCSF Institute for Health & Aging. • Richard M. Rosenberg – director of the UCSF Foundation Board; chair of the UCSF Medical Center Executive Council. • Martha Ryan – founder and executive director of the Homeless Prenatal Program. • Pablo D. T. Valenzuela – co-founder of Chiron Corporation; co-inventor of the first recombinant vaccine against the Hepatitis B Virus; and adjunct professor in the UCSF Department of Biochemistry. The UCSF Medal recognizes outstanding personal contributions in areas associated with the University’s mission, including providing top-quality patient care, improving understanding of the factors that affect human health through research and teaching the next generation of health sciences leaders.

Online Registry to Drive Brain Disease Research

Dr. Judy Melinek is a medical examiner and Assistant Clinical Professor of Pathology at the UCSF Medical Center.

A prime example of this disconnect comes in an episode of Bones when Dr. Brennan, who is portrayed in the first several seasons as highly practical and unfeeling, must testify against the defense’s very charismatic expert witness. She has to learn how to alter her speech to win the jury’s favor. Melinek also addressed the perception that medical examiners are an “arm of the prosecution,” which flies in the face of their work as objective investigators. In a paper titled, “The Ethics of Working as a Retained Forensic Expert,” Melinek explored the tactics used by the prosecution to persuade government-employed medical examiners to serve, not as an independent expert, but as a tool for conviction. She argued that this view of medical examiners might be changed if all counties hired medical examiners as private contractors instead. So, if you are a crime show fan and you have the opportunity to serve as a juror, just remember to take everything you have watched on TV with a brick of salt and don’t apply the realities of the TV world to the trial in front of you. To learn more about the science of forensic pathology, check out Melinek’s blog (www. pathologyexpert.com/drjudymelinek/) and look out for her book, Working Stiff, due out in August.

Nicole Croom is a second-year student in the School of Medicine.

A new online project led by researchers at UCSF promises to dramatically cut the time and cost of conducting clinical trials for brain diseases, while also helping scientists analyze and track the brain functions of thousands of volunteers over time. With easy online registration, the Brain Health Registry is designed to create a ready pool of research subjects for studies on neurological diseases, such as Alzheimer’s and Parkinson’s, as well as depression, post-traumatic stress disorder and many other brain ailments. About one-third of the cost of running a clinical trial comes from having to recruit patients, and many trials fail or are delayed because of it. The Brain Health Registry is the first neuroscience project to use the Internet on such a scale to advance clinical research, according to Michael Weiner, MD, founder and principal investigator of the initiative and a professor of radiology, biomedical engineering, medicine, psychiatry and neurology at UCSF. He will serve as principal investigator of the Alzheimer's Disease Neuroimaging Initiative, the largest observational study of Alzheimer's.

Pancreatic Cancer 'Dream Team' Tackles Deadly Disease UCSF has been selected to join a national “dream team” on pancreatic cancer, part of a project designed to accelerate treatment and discoveries for one of the most deadly forms of cancer. The team was announced on April 7 during the annual meeting of the American Association for Cancer Research. The fourth leading cause of cancer death in the U.S., according to the National Cancer Institute, progress in treating pancreatic cancer has long been hobbled by a difficulty at detecting it early and by a poor response to therapies by patients. While it is relatively rare, it now kills nearly as many as breast cancer and only about six percent of those diagnosed with it live as long as five years. The goal of the dream team is to turn pancreatic cancer into a treatable disease. Margaret Tempero, MD, a UCSF professor of medicine and director of the UCSF Pancreas Center, will lead the UCSF portion of the research.


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PeerJ, eLife and F1000 represent three new alternatives to the traditional scientific publishing subscription model.

Open Access » FROM HOME PAGE

A Numbers Game Biomedical sciences journals charge the highest APCs of any science, technology and medicine (STM) discipline, with the average fee in 2010 running just over $1,000, according to an article by Drs. David J Solomon and Bo-Christer Björk published in the Journal of the American Society for Information Science and Technology. According to their calculations, the biomedical field spent over $64 million in APCs for open access journals, with many journals charging between $700 and $1800. “I’m seeing some pushback from faculty, mostly to the ‘author-pays’ model of open access,” said UCSF Library’s Director of Serials Anneliese Taylor. “Those who are opposed think that the university is pushing costs off on researchers, while at the same time their research awards are decreasing.” But this should not be a disincentive for scientists to publish in open access journals, according to Johnson. “The critical thing is to look at the entire cost of a research project—and the journal publication charges are a very small part of that,” he said. “Compared to the salaries that are being paid to people and the cost of supplies and the infrastructure, it’s a very small percentage of the overall cost. Avoiding APCs And for those authors who cannot afford to pay or refuse to pay APCs, there are many open access options. “If you look at the Directory of Open Access Journals (which has close to 10000 journals), not even 50 percent of those charge a fee or any processing or publication charge,” explained Taylor. “The reason that’s not as

Photo by Hadar Green Dr. Randy Schekman is editor of eLife.

widely known is just because the ones that have really made a reputation for themselves do charge.” In fact, open access journals with APCs were more cited than their free counterparts, according to the Solomon and Bjork article. Even if researchers limit their options to open access journals with impressive impact factors (and APCs that go along with them), many offer discounts and waivers for researchers with dwindling funds or located in foreign countries deemed worthy of discounts. For example, PLoS, like many other open access journals, participates in a Global Participation Initiative, which segregates countries into three groups: one that pays the normal fee without discount, one that pays a $500 flat fee for publication and a group that pays no fee Photo courtesy of PeerJ at all. Even Cell Reports, the open PeerJ founders Drs. Peter Binfield (left) and Jason Hoyt. access journal with a $5,000 APC, will consider waiving its fee on a case-by-case “By their account, it’s not cheap to do what basis if authors have difficulty paying. they’re doing (because they’re adding quite a For individual scientists, APCs are often bit of value to their publication) but they have manageable with discounts and careful jour- the money to do it,” said Anneliese Taylor. nal selection regardless of the scientist’s fund“The founding sponsors of eLife feel that ing level. Universities, on the other hand, see they should support publishing the best work a larger shift—one that ultimately results in a in the life sciences with no consideration of higher cost of publication for the community profit,” said Schekman. as a whole. eLife plans to remain APC-free for the “When we look at the output from next two years as a way to encourage submisUCSF—about 6000 articles every year—it sions, and then initiate an APC some time afwould actually cost the university more to pay ter that, according to Schekman. open access APCs compared to what we pay “This will defray some of our expenses for subscriptions,” said Taylor. “We just can’t but I believe we will continue to rely on prigo there based on the current APC model—it vate and national foundations who believe wouldn’t be economically sustainable or sen- in our model and will offer financial supsible to do that.” port to help us achieve our goals,” he said. PeerJ, a journal funded by Drs. Jason Hoyt New Publishing Alternatives and Peter Binfield, is also trying a new model. If APC-based business models are ultimately unsustainable, is there a better model? One option is to create an entirely new business model—one that doesn’t require fees from the authors or the subscribers. eLife is a new journal, heavily subsidized by Max Planck, Wellcome Trust and the Howard Hughes Medical Institute (HHMI), that is currently free to publish in. Unlike many other journals, eLife plans to make the peer review process transparent and faster by having the editor “and his/ her referees confer online to arrive at a consensus decision on the fate of a paper under review,” said Dr. Randy Schekman, 2013 Nobel Prize Laureate and editor of eLife. “Importantly, the reviewers are identified to each other so that they know going into an eLife review session that they will have to consider the views of peers in their field and may not do so behind a screen of anonymity.”

Photo courtesy of F1000 Rebecca Lawrence is Director of New Product Development at F1000Research.

Instead of charging a publishing fee for each article, PeerJ charges a low, one-time fee per author of the publication, which can be as low as $99/author for a basic membership. Minimal membership duties include performing a formal review of a submitted PeerJ manuscript or contributing informal comments on submissions or accepted papers at least once a year to maintain the lifetime membership. After this one-time fee, authors can publish as frequently as their plan allows—for example, the $99 plan allows for one publication in PeerJ per year. “That was one of the reasons we started PeerJ—to try and make the process of publishing open access content as cheap and as accessible as possible for the author,” said Binfield, one of the cofounders of the company. Not surprisingly, PeerJ has the potential to save scientists and institutions thousands of dollars per publication. Some of the newest open access journals are sticking with the tried and true APC. F1000Research, launched in early 2013, is an online open access journal unique for its postpublication peer review process. Their goals are three-fold: “To massively speed up the publication process—from the time you’re ready to publish to the time other researchers get to benefit from the research; get rid of bias in the refereeing system; and open up the data behind that research,” according to Rebecca Lawrence, Director of New Product Development at F1000Research. F1000’s focus on transparent post-publication review, in which invited peers make their formal reviews public along with the published manuscript, makes it a unique model of peer-reviewed scientific publications. But to cover the costs of publication, F1000 decided on “a standard APC model in some regards, but significantly cheaper than some of the major open access journals,” said Lawrence. Indeed, APCs for F1000 range from $250 to $1000 and include web hosting of online data and article revisions and updates (along with new digital object identifiers, or DOIs) in addition to traditional APC benefits, which typically include peer review, journal production and article hosting and archiving. With some open access journals getting pushback about high APCs, the traditional subscription-based publishing model could even find itself back in favor. Trade journals associated with a foundation, such as Science with the American Association for the Advancement of Science (AAAS), or Molecular Biology of the Cell with the American Society for Cell Biology, are often non-profit enterprises and use subscription fees for more than just covering journal cost. For Science, excess income from subscriptions supports other activities of the society such as scholarships for students to visit an

OPEN ACCESS » PAGE 5


synapse.ucsf.edu | April 17, 2014 | 5

Open Access

NEWS

Graduating Professional Students: Set up Exit Session for Loans

» FROM PAGE 4 annual society conference, according to Dr. Bruce Alberts, the former editor-in-chief of Science. “Highly selective journals like Science or Nature accept something like one paper in 20 submissions, making the operation so costly that an open access fee would need to be something like $20,000 per article to cover journal publication costs,” he said. While it seems unlikely that journals like Science will become open access, Alberts makes the distinction that “open archive seems to me to be the best bet for the future”—a model where articles aren’t immediately available for free but are archived in a way that makes them freely available after a certain period of time.

By Carol Ann Simpson Contributing Writer

A

Photo by Tom Kochel Bruce Alberts is the former editor-in-chief of Science.

Institutional Funding Shift One common concern amongst scientists is that page charges for open access journals will continue to rise, thereby pricing out young laboratories with small budgets. It’s a serious enough concern that universities are taking note. Many universities have begun pilot funds for cash-strapped laboratories seeking to publish in open access journals, including Carnegie Mellon University, Harvard University, many UK universities through the Research Council UK, and the University of California. Information on UCSF’s open access pilot fund can be found at library.ucsf. edu/services/scholpub/oa/fund. One option for scientists is to shift their publishing to journals without APCs, such as eLife and PeerJ, but it remains to be seen how popular these nascent journals will become with the scientific community, as measured by their impact factor. In the absence of these radically new publishing models, how will universities adapt to

the changing fiscal environment with regards to scientific publishing? UCSF’s Keith Yamamoto, Vice Chancellor for Research, Executive Vice Dean of the School of Medicine, and Professor of Cellular and Molecular Pharmacology, thinks institutions should take on the responsibility for financing the publication of scientific research. “I think that universities should consider publishing a cost of doing business, just like electricity,” he suggested. “If you don’t publish your work, it’s just like not doing it. The institution is outsourcing one of the critical functions of the faculty, which is scholarly publication of the work. They outsource electricity to PG&E. They outsource water to whatever it is. There’s a twin responsibility from the funder and the institution that paid for that work, and it’s completely justified."

Alexandra Greer recently received her PhD and is now a postdoc at Genetech.

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Order Custom DNA & RNA Oligos, qPCR Probes, siRNA and PEPscreen® peptide libraries and receive a FREE gift of your choice when placing a $50 minimum order. Reference promo code 250 when ordering. Offer valid for University of California San Francisco customers placing orders through BearBuy. Customers with qualifying purchase will be contacted in order to select their free gift. Gift options include a T-shirt, acrylic tumbler with lid & straw, or insulated travel mug. Please allow 6-8 weeks for receipt of your gift. One gift per customer. Valid until May 16, 2014.

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©2014 Sigma-Aldrich Co. LLC. All rights reserved. SIGMA and SIGMA-ALDRICH are trademarks of Sigma-Aldrich Co. LLC, registered in the US and other countries. Where bio begins is a trademark of Sigma-Aldrich Co. LLC. PEPscreen is a registered trademark of Sigma-Aldrich Co. LLC.

81755 UCSF Synapse Newspaper Ad Update.indd 1

81755

2/25/14 11:09 AM

bout to graduate from the School of Medicine, Dentistry or Nursing? Congratulations! But before you leave us, you will need to take care of a little business: An exit session is mandatory for anyone who received loan funds while at UCSF and attendance will be verified. If you borrowed any university-based loans, (Perkins, Health Professions , Loan for Disadvantaged Students, Nursing Student Loan, Nurse Faculty Loan or University Loan) you must attend an exit session with Student Accounts and must call to schedule your attendance for one of the sessions listed below. Bring two references (two relatives and two non-relatives and address and telephone information. Direct (Stafford)/Grad PLUS-only loan recipients do not need to schedule an appointment and may attend the session of their choice. All Direct (Stafford) and Graduate PLUS loan recipients must complete an online exit counseling session at www.student-

loans.gov. This online session usually takes about 15-20 minutes and can be done either before or after the scheduled sessions: •• Medicine: May 6, 2014, 3-5 p.m., HSW-302 •• Medicine: May 7, 2014, 3-5 p.m., CS-701 •• Nursing: May 14, 2014, 3-5 p.m., MS-214 •• Nursing: May 21, 2014, noon-2 p.m., Toland Hall •• Dentistry: May 28, 2014, 10 a.m.-noon, Toland Hall •• Dentistry: May 29, 2014, 1-3 p.m., Toland Hall To schedule you attendance at one of the sessions, university-based loan recipients should contact Student Accounts by April 25: Cherry Lazaro (415) 502-8206 Last names beginning with A-L Jackie Beddow (415) 476-8699 Last names beginning with M-Z Thank you!

Carole Ann Simpson is the Resource Advisor in Student Financial Aid.

Free Online Classifieds for UCSF Students & Staff on Synapse Who needs CraigsList when you can post FREE classified ads on the Synapse website? All you need is a ucsf.edu email account. Go to synapse.ucsf.edu/classifieds to sign up today!


6 | April 17, 2014 | synapse.ucsf.edu

MEDICINE

UCaSeFiles: Clinical Cases from the UCSF Wards

W

elcome to UCaSeFiles, a column in which short case vignettes are submitted by UCSF medical students, residents and attendings based on the stories of real patients seen on the wards, with each vignette followed by a brief discussion of salient learning points. Some cases are rare diagnoses; others are common ailments that might have had a unique or puzzling presentation. All are welcome to submit your medical mysteries to Theresa Poulos (Theresa.poulos@ucsf.edu) for editing and final submission. By Theresa Poulos and Jenny Cohen Staff Writers

Multiple Chief Complaints: Can There B1 Unifying Diagnosis? Case Submitted by: Theresa Poulos, MS3, Marisa Hernandez-Morgan, MD, and Marcia Glass, MD The Patient: A 48-year-old woman presented with five days of abdominal pain and difficulty breathing, a week of hemoptysis and painful swelling of her left lower extremity. Her history was notable for alcohol dependency with delirium tremens, COPD and hepatitis C. She was afebrile and tender to palpation in the epigastric area, with erythema and induration of the left abdomen. She had two-plus pitting edema to the mid-thigh bilaterally; both lower extremities showed marked erythema and were warm and tender to touch. She had a tremor of the upper extremities bilaterally. Her toxicology screen was positive for alcohol, and lactate was elevated at 2.6 mmol/L. Lower extremity Doppler was negative for deep vein thrombosis. CT of the abdomen was only remarkable for diffuse subcutaneous edema. Transthoracic echocardiogram findings were consistent with a high cardiac output. The Diagnosis: Fluid accumulation resulting in edema is a common presentation. Distinguishing between dependent and diffuse soft tissue edema can help to narrow the differential and result in more timely diagnosis and treatment. The underlying cause of this patient’s anasarca is high-output heart failure due to severe thiamine deficiency. Thiamine deficiency can manifest as a peripheral neuropathy (dry beriberi), or with predominantly cardiac symptoms (wet beriberi). Initially in wet beriberi, peripheral vasodilation results in a decreased SVR and increased venous return. Continued deficiency leads to impaired myocardial function because thiamine acts as a coenzyme in carbohydrate metabolism. Specifically, thiamine deficiency results in impaired utilization of lactate, which then accumulates in the blood causing elevated

Chancellor’s Concert Series

S p r i n g

/ 2014

Presenting exceptional artists in classical music on a science campus

April 3, 2014

Schubert’s most difficult piano piece Betty Woo, piano Schubert: Wanderer Fantasy Golijov: Fantasy on a Chorus from St. Mark’s Passion

April 10, 2014 Yuna Lee, violin Sebastien Gingras, cello Akimi Fukuhara, piano Brahms: Piano Trio No. 3 in G minor, Op. 110

May 1, 2014

Contemporary piano trio Lee Trio Philip Lasser: Piano trio in F-sharp

May 22, 2014 June Choi Oh, piano Sarn Oliver, violin Grieg Sonata for Violin and Piano No. 1 in F Major Op. 8

April 24, 2014

Bartok, Liszt and Chopin piano works Machiko Kobialka, piano Bartok: Sonatina Liszt: Hungarian Rhapsody No. 14 Chopin: Ballade No. 4, Op. 52 The Chancellor’s Concert Series is a professional, classical music series funded by the Chancellor, to enrich the quality of life at UCSF and in the community. These half-hour concerts feature artists primarily from the San Francisco Symphony and the San Francisco Conservatory of Music faculty. This series was founded in 1998.

Director: Pearl Toy, M.D. Poetry: David Watts, M.D. Program notes: Nelson B. Schiller, M.D. Production: Arts & Events Check updates at: www.campuslifeservices.ucsf.edu

Call: 415.476.2675

Free Admission / Noon on Thursdays

Silence must be maintained at all times during the performance. In consideration of the artists and the audience, please silence beepers, alarms, and phones. Taping of the performance is prohibited. Attendance by children under 5 is discouraged. Please come and go quietly at pauses during the performance.

12:00 – 12:10 pm Seating 12:10 – 12:15 pm Poetry reading by David Watts, M.D. 12:15 – 12:45 pm Concert (No eating during performance)

Cole Hall / 513 Parnassus Avenue / San Francisco

Select concerts will be available for live streaming or to conveniently watch at a later time. Please use this link: http://tinyurl.com/chancellorsconcerts

serum lactate, as was seen in this patient. While elevated blood lactate is nonspecific, it has been used in the diagnosis of beriberi. With continued vasodilation, the kidneys detect a relative volume loss and respond by conserving salt. Fluid is re-absorbed, leading to diffuse edema, consistent with this patient’s otherwise odd pattern of fluid retention. The body cannot produce thiamine, and is only able to store up to 30 mg in tissue. The halflife is 9 to 18 days, so individuals who lack thiamine in their diet will become deficient within a month. Thiamine deficiency is rare in developed countries because most foods are fortified, however the WHO has documented outbreaks of beriberi among refugees and in developing countries—particularly Thailand and in sub-Saharan African—where diets are based on thiamine-poor staples such as polished rice and cassava. This patient was deficient as a consequence of poor nutrition associated with her chronic alcoholism. Gastric bypass patients and individuals on “fad” diets are also at risk. Therefore, physicians need to consider thiamine deficiency when evaluating a patient with diffuse anasarca. The diagnosis is largely clinical, because blood thiamine levels may not accurately represent the amount in tissue. IV thiamine should be administered whenever deficiency is suspected.

Theresa Poulos is a third-year UCSF medical student and Jenny Cohen is a doctor (R1 – UCSF Internal Medicine).


synapse.ucsf.edu | April 17, 2014 | 7

P&T Competition

Grad School Illustrated

by Jillian Varonin

» FROM HOME PAGE

all pharmacy students, faculty and staff. “We could not thank the school enough times for everyone’s tremendous support,” said Edna Cheung. “They believed in us more than I believed in myself!” Adding to the accomplishment, this win also marks the first time UCSF has nabbed back-to-back first place finishes. As one of the top eight finalists selected to compete live, the UCSF P&T team presented and defended their formulary decision for Eylea® for a hypothetical health plan. The other finalists were Rutgers University, University of Washington, University of Illinois at Chicago (third place), Western University of Health Sciences, Loma Linda University, University of the Pacific and University of Southern California (second place).

Linda Chen is a second-year pharmacy student.

Jillian Varonin is a fourth-year BMS student.

MIND&BODY

Let’s Get Physical...Therapy! The Top 10 Scariest Things I See at the Gym By Ilka Felsen Staff Writer

A

s a physical therapy student at UCSF, I am often asked if I see people doing exercises incorrectly at the gym. My answer: all the time! I’ve decided to share below some of the most common gym errors I’ve witnessed in my time here. But, I’d like to make the following disclaimer: first, that I am not (yet) licensed, and therefore excused from being the end-all, be-all source of exercise information. And second, that physical therapy exercise differs dramatically from fitness exercise, with the former focused on confronting a medical condition, and the latter focused on toning up and meeting fitness goals. So, here are the scariest things I see at the gym: 1. Lifting weights with hyperextended backs, rounded backs, or anything but a stable back. The core should basically always be engaged. Otherwise, harmful stress deforms the spine. Activate your abdominals during any and all gym activities, especially during lifting!

3. Rounded back position during cycling. There will naturally be some flexed curvature of the spine while leaning over to cycle. But too much spinal flexion is a red flag for back pain, and ultimately, a herniated disk. 4. The ponytail sign. Guys have this problem too, but it’s not so apparent without a ponytail. The ponytail sign is a term we use for someone who bounces up and down so much when they run, that their ponytail wags side to side. The ideal vertical displacement during running should be no more than three inches. 5. The thunder sign. This a term I just dubbed myself, but anyone who has jogged next to someone who treads heavily has experienced the thunder sign. This happens when the person next to you—or worse, you!—is landing so heavily that their footsteps drown out your music. Landing loudly is dangerous, and indicates excessive forces on the knees, ankles and hips of this poor runner.

The author demonstrates poor plank form (above) and her best plank form (below).

ASIAN EGG DONORS NEEDED

I’m guilty of this myself, because it’s a lot more fun to coast on the elliptical while I watch Netflix, than to hold my body up. While using the handles can activate the shoulder girdle, I see more people use them as crutches, and end up excessively rounding over their machines (scary back problems on the horizon). So let’s all man up, and use those handles less!

We are seeking attractive and intelligent women under the age of 29 to help our clients create their family. If you are interested in becoming an egg donor or just want to receive more information about the process please contact us. Information is free and there is never an obligation if you inquire.

7. Leaning obnoxiously forward over iPhones, magazines and iPads. I get it—I too like to “lean in,” a la Sheryl Sandberg. But this is a time when that is actually a bad idea. Our heads should be held high when we work out, for better cervical spine alignment and shoulder girdle placement. No more hunching over our technology!

info@aperfectmatch.com or 1-800-264-8828

8. Planks that look more like downward dog. The plank is an amazingly powerful abdominal exercise. But that also makes it really hard to do, and very tempting to sneak in some weird posturing instead. I’ve seen butts high in the air, backs sagging, shoulder blades poking out, heads dropped almost to the floor, and some other very interesting

2. Working the same muscles every time. There are some people who hog the treadmills, or the row machine, or the quad press, or the weight room...every...single...day. That chick who is always on the stair stepper? Get

off ! Workouts should be balanced to prevent overuse and imbalance syndromes. That means some days should be spent on the upper body, and other days on the lower body, endurance or stretching. And some days should be spent resting!

6. Relying too much on the elliptical handles.

$25,000 plus expenses CA Health and Safety Code Section 125325: “Egg donation involves a screening process. Not all potential egg donors are selected. Not all selected egg donors receive the monetary amounts or compensation advertised. As with any medical procedure, there may be risks associated with human egg donation. Before an egg donor agrees to begin the egg donation process, and signs a legally binding contract, she is required to receive specific information on the known risks of egg donation. Consultation with your doctor prior to entering into a donor contract is advised.”

interpretations of the plank. The key to the plank is to be a plank—so think board! 9. Super buff dudes working all of the big muscle groups, and neglecting the more subtle stabilizers. Bicep curls and bench presses are the staple in many a gym-goer’s upper body workout, while the smaller shoulder muscles (subscapularis, teres minor, infraspinatus, and supraspinatus) are overlooked in the mission to bulk up. But these smaller muscles are super important scapular stabilizers, and function heavily in almost any arm movement and in injury prevention. 10. Knock-kneed squats. Squats should be done with the knees moving in line with the toes, not inside or outside of the foot, and certainly never touching. Watch your knees carefully, and if they deviate even the slightest hair side to side, your form needs a little extra love and attention.

Ilka Felsen is a second-year physical therapy student who enjoys watching people walk, palpating joints and muscles and talking about physical therapy.


m a . r h e s t y e b m a B rmo . e t h e T ssin a . B cum l . . l r a i i T by o cha a B cking n. r o R byBjö a B ll. o D ttle. . o s B per e. a i n D ox O b X e m i T . d d a D livere e D T:10”

8 | April 17, 2014 | synapse.ucsf.edu

T:16”

When you can get delivery from all of your favorite stores in 24 hours or less, a diversion is never more than a few clicks away. google.com/express


FOOD

synapse.ucsf.edu | April 17, 2014 | 9

The Scoop

Dreams vs. CREAM: Battle of the Ice Cream Sandwich By Dawn Maxey Staff Writer

C

REAM is a Telegraph Avenue staple, serving a big scoop of ice cream sandwiched between two freshly baked cookies for the bare bones price of $2. The line regularly extends around the corner and down the block. In January, a competitor shop named Scoop Dreams opened up directly across the street, offering its own homemade ice cream sandwiches for the same price. Battling ice cream sandwich joints? This was an opportunity too good for The Scoop

CREAM 2399 Telegraph Ave., Berkeley (510) 649-1000 Scoop Dreams 2401 Telegraph Ave., Berkeley (510) 704-1146 team to pass up. With special guest reviewer pediatrician Abhay Dandekar, we traveled to Berkeley to assess the competition. When we arrived, the clash was already in full swing. Taking advantage of people’s waning patience in the stretched out CREAM line, a Scoop Dreams employee was periodically handing out buy-one-get-one-free coupons to people waiting. The trick worked—each time, a handful of people defected across the street and put their dollars down for the competitor sandwich instead. Ever-hungry for a good deal, we got our hands on a few coupons and started our taste

test at Scoop Dreams. The concept is simple: select your cookie (at the time: Chocolate Chip and Double Chocolate Chip) and then select your ice cream (a wide variety of Double Rainbow flavors). We walked out with Coffee ice cream in Double Chocolate Chip cookies, Mint ice cream with Double Chocolate Chip, and a cup of the Lychee ice cream. Praise was given for a “no frills experience,” “a good, if stolen concept,” “great value for a large dessert” and “delicious soft cookie with melted chocolate chips.” On the flip side, points were docked for cookie availability (they had run out of Chocolate Chip), ambiance (it’s oddly located inside of Rasputin Records) and the feeling that Scoop Dreams had been created without much foresight. For example, Dandekar noted the lack of branding on the ice cream cups, proclaiming, “I don’t want a Double Rainbow cup. I want something that says Scoop Dreams.” The shop has a basketball hoop mounted so that customers can hypothetically shoot for a free scoop. When we asked the only employee about it however, she mumbled something about needing to install a protective net to prevent stray shots from contaminating the ice cream. Co-Scoop editor Theresa summed up our overall feelings: “There was nothing about it I didn’t like, but nothing I loved.” Scoop Dreams sandwiches polished off, we moved on to our next conquest: CREAM. After a 15-minute wait in line (once inside the store, the line moves at a surprisingly rapid pace), we stepped outside with a scoop of

Photo by Dawn Maxey/MS3 The line for the popular ice cream shop CREAM in Berkeley regularly extends around the corner and down the block.

Salted Caramel ice cream in between Cinnamon Sugar and Double Chocolate Chip cookies, in addition to small cups of Peanut Butter Twist, Strawberry and Pistachio ice cream. We spread our wares out on top of a rusting newspaper stand and systematically dug in. After a disappointing taste from one cup, I moved on to sample the next flavor, hoping that there’d be an improvement. To my dismay, each bite was the same—a tasteless cold mass of saccharine, as if someone had frozen bushels of cotton candy and bewitched it into a creamier form. I wasn’t alone. The rest of the Scoop team described what they tasted as “gummy,” “flavorless” and “it coats your mouth—in a bad way.” Even the cookies were bland and subpar, despite looking wonderfully soft and scrumptious. After a few minutes, the scene was dismal: three largely unfinished cups of melting ice

cream alongside broken pieces of discarded cookie. And four medical students looking very sick to their stomachs. Despite CREAM’s strategic location underneath the Princeton Review (what better shop to cater to legions of hypoglycemic hostages of standardized exams?) and reasonable price, we unanimously agreed that CREAM had sold us one of the worst tasting ice creams to date and that their hordes of followers are a drone-like mass that do not possess taste buds. The Scoop team overall learned a few valuable lessons: do not eat more than one ice cream sandwich at a time. And despite their clever marketing and fantastic concept, the ice cream sandwich shops on Telegraph unequivocally leave patrons dreaming of something more.

Dawn Maxey is a third-year medical student.

Photo by Dawn Maxey/MS3 Mint ice cream sandwiched between two Double Chocolate Chip cookies from Scoop Dreams, a new ice cream sandwich shop on Telegraph Avenue in Berkeley.


10 | April 17, 2014 | synapse.ucsf.edu

EGG DONORS NEEDED We are seeking attractive and intelligent women of all ethnicities under the age of 29 to help our clients create their family. If you are interested in becoming an egg donor or just want to receive more information about the process please contact us. Information is free and there is never an obligation if you inquire.

info@aperfectmatch.com or 1-800-264-8828

$15,000 plus expenses CA Health and Safety Code Section 125325: “Egg donation involves a screening process. Not all potential egg donors are selected. Not all selected egg donors receive the monetary amounts or compensation advertised. As with any medical procedure, there may be risks associated with human egg donation. Before an egg donor agrees to begin the egg donation process, and signs a legally binding contract, she is required to receive specific information on the known risks of egg donation. Consultation with your doctor prior to entering into a donor contract is advised.”

THIS AIN’T YOUR DADDY’S LUBE IS LUBE THE NEXT PrEP? help us find out.

UCSF DEPARTMENT OF SURGERY

27th Annual

Resident Research Symposium Friday, April 25, 2014 9:00 am – 2:00 pm Resident Presentations

2:00 pm Keynote Presentation

“Observations from the American College of Surgeons Quality Improvement Programs”

THE STRENGTH TO HEAL

3:00 pm Awards Presentation

starts with our scholarship.

TOLAND HALL

Capt. Ana Morgan, M.D., HPSP Medical Recipient Brooke Army Medical Center, Texas

You can begin training for the career you’ve always dreamed of with financial assistance from the U.S. Army. Through the Health Professions Scholarship Program (HPSP)*, you could be eligible to receive a full tuition scholarship for an accredited medical program. The HPSP provides reimbursement for books, laboratory equipment and academic fees. You’ll also receive a sign-on bonus of $20,000 and a monthly stipend of $2,157. During breaks, you’ll have the opportunity to train alongside other members of our health care organization. To learn more, call (650)347-3967 or visit San Mateo Medical Recruiting Center 400 S. El Camino Real, STE 450 San Mateo, CA 94402 Email: usarmy.knox.usarec.list.9e3j@mail.mil www.goarmy.com/amedd.html

*Certain requirements and eligibility criteria apply. ©2013. Paid for by the United States Army. All rights reserved. Information subject to change.

533 Parnassus Avenue, U‐142 San Francisco, CA

Clifford Y. Ko, MD, MS, MSHS, FACS

J. Englebert Dunphy Visiting Professor Director, Division of Research and Optimal Patient Care Director, National Surgical Quality Improvement Program (ACS NSQIP) American College of Surgeons Professor of Surgery, University of California Los Angeles

The Resident Research Symposium is an annual event showcasing the laboratory research of residents, fellows and medical students in the Department of Surgery. For more information, visit our website at: http://www.surgery.ucsf.edu. This event is sponsored by educational grants from the Howard Naffziger Surgery Fund. UCSF D EPARTMENT OF S URGERY R ESIDENT & M EDICAL S TUDENT E DUCATION O FFICE Telephone: (415) 476‐1239 Email: EducationOffice@ucsfmedctr.org


synapse.ucsf.edu | April 17, 2014 | 11

PUZZLES The Weekly Crossword 1

2

3

4

by Margie E. Burke 5

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9

10

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12

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ACROSS 1 Song section 14 15 16 6 Waikiki's island 17 18 19 10 Cashless deal 14 Muslim prince 20 21 22 23 24 (var.) 27 28 26 15 Horner's rew ard 25 16 Hankering 29 30 31 32 17 Second crop 34 35 18 Archaeologist's 33 discovery 36 37 19 One-sidedness 38 39 40 41 42 43 44 20 Radio problem 22 At all 45 46 47 24 Dead heat 25 Ditzy type 50 51 48 49 27 Neon or nickel 52 53 54 55 29 Programmer's output 56 57 58 59 60 30 Aw esome! 61 62 63 32 Calcutta coin 33 Annapolis grad. 64 65 66 34 Deep cut Copyright 2014 by The Puzzle Syndicate 35 Show s the w ay 36 Passed aw ay 61 Film part 8 Desert Storm 35 Type of hickory for died, e.g. vehicle 62 Mrs. Peacock's 36 Sponsorship game (var.) 38 Dicker over 9 Carrot's flow er price cluster 63 Lazy sort 37 Hotel w orker 41 "Con Air" actor 64 Cry of disgust 10 Undersea 38 "Okie From Musprow ler kogee" singer 42 NBA position, 65 Nelson of early briefly film musicals 11 Like some 39 Flyboy candidates 45 Sidestep 66 Little darlings 40 Venetian boat 46 Related (to) 12 80's flick, "____ 42 "Apocalypse All Odds" Now " director 47 Steamed up 48 Root used in DOWN 13 Old Spanish 43 Movie preview energy drinks coins 1 Big name in 44 Apartment fashion Cocktail party dw ellers 50 Broom closet 21 Week of 4/14/14 - 4/20/14 item serving 2 Poker face's 46 Long-standing lack 52 Wander about 23 Calm state 47 Walked w ith purpose 53 Yuletide tune 3 Perks 26 Cable competitor 55 La Brea sight 4 See red 28 Seriously injure 49 Present time 56 Proton's place 5 "Sesame Street" 31 Chess 51 Appetizing regular declaration 58 Cubby hole 54 ____ and clear 60 First Pulitzer 6 Decide on 34 Netherlands 57 Brave Prize novelist dollar, once opponent? 7 Sunburn soother 59 Anthem author

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Edited by Margie E. Burke

Difficulty : Medium

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HOW TO SOLVE:

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        (Answer appears elsewhere in this issue)

Copyright 2014 by The Puzzle Syndicate

This Year, Take Time Take Time for Reflection, for Prayer, for Community St. John’s United Church of Christ A progressive Christian community welcoming all Maundy Thursday Supper & Service Thursday, April 17, 6:30 p.m. Easter Sunday Worship of Joy Sunday, April 20, 10:00 a.m. 501 Laguna Honda Blvd at Woodside www.sfstjohnsucc.org 415- 731-9333 Forest Hill Muni Metro Station K, L & M lines Muni bus lines #43, #44, #36, & #52

HUMOR/FAKE NEWS

Student Hopelessly Lost After Forgetting Gmail Password By Staff Humorist

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n what nursing students are calling the saddest story they’ve encountered all year, classmate Jaclyn Hernandez has fallen from favor of the Great Google Deity after forgetting her Gmail password. “I haven’t been able to access emails for eight days now,” said Hernandez. “I would look up the password, but I stored it on a draft email to myself that has all my passwords on it. Not a very good idea in retrospect.” Hernandez admitted she may have become over-reliant on Gmail—she does not know what her schedule is, who her friends are or where even her house is.

Piled Higher and Deeper by Jorge Cham

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Solution to Sudoku

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www.phdcomics.com

Local support has provided a modicum of relief, but hasn’t come close to restoring the life Hernandez once enjoyed. “It’s all gone downhill so quickly. I wish I could look up a way to just fix it all. I don’t know why I’m here or why this has happened to me. What have I done to anger the Great Google?” Hernandez said that sacrifices to the Great Google, including wailing and gnashing of teeth, have done nothing to sway her fickle digital overlord so far, but that she would continue trying because managing her email and schedule through a program like Yahoo would be far worse.

Parnassus Poets A New Life “A new life”, he says smiling, sitting up in bed.

        

“Not just a second chance”, he says firmly, “but a new life, with a new heart!” And he looks at me and laughs. Already the years drop off, his face looking younger, his body renewed with hope. ~ Rev. Malaena Nahmias Chaplain-Intern, Spiritual Care Services title: "Comfort Zone" -­ originally published 3/10/2014


12 | April 17, 2014 | synapse.ucsf.edu

Solutions

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Solution to Sudoku

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Vision Optical Look sharper. See better. Find us easier, too. Contemporary prescription glasses, sunglasses, and contact lens fitting Millberry Union, B1 For appointment & information 415.476.3100 Hours: M-F 8:30 am-5:00 pm

look sharper Vision Optical

Open at Parnassus & Mission Bay Campuses

for your convenience we accept: All major Credit Cards • Recharge for catering Bear Hugs • UCSF Resident Meal Card

breakfast, lunch, or dinner…

Parnassus: Millberry Union I Level, Parnassus, 415.661.0199 Open Daily 7:00 am-10:00 pm Mission Bay: 550-B Gene Friend Way, Mission Bay, 415.865.0423 Mon-Fri 7:00 am-9:30 pm / Sat-Sun 8:00 am-9:00 pm

You’re Funding Fun! A portion of every dollar you spend at campus retail vendors helps support Arts & Events at UCSF

Get a gourmet taste of Italy. panini, insalate, zuppa, hot pasta, gelato, dolci We offer student discounts. Millberry Union, Plaza Level 415.681.9925

Mon-Thu, 6:30 am-6:00 pm Fri, 6:30 am-4:00 pm Closed Sat & Sun

You’re Funding Fun! A portion of every dollar you spend at campus retail vendors helps support Arts & Events at UCSF

You’re Funding Fun! A portion of every dollar you spend at campus retail vendors helps support Arts & Events at UCSF

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