Temple University School of Medicine - Highlights of Basic and Clinical Research - 2014

Page 30

MAKE EXISTING CANCER TREATMENTS

Which cell signal is the ideal target?

MORE EFFECTIVE?

Why does animal DNA repair differ from human DNA repair?

HOW CAN WE

When is my hypothesis ready for first-in-human testing?

Philadelphia chromosome. The vast majority of patients with chronic myelogenous leukemia have a distinctive abnormal swapping of chromosomal segments (between chromosomes 9 and 22). This “Philadelphia chromosome” was co-discovered by researchers at Fox Chase Cancer Center, a breakthrough that prompted development of highly effective targeted treatments. note: This is a corrected copy. The original report inaccurately linked the awarding of a Nobel Prize for work done by Fox Chase Cancer Center researchers in 30the co-discovery SECTION | SECTION of the “Philadelphia chromosome.” We apologize for that error.

{ What } COMES AF T ER T HE H U MAN GENOME P RO JECT ?

Why is that one gene turned on in cancer?


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