Molecular Pathology
Molecular Biology Principles
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Molecular Pathology
Molecular Biology Principles
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2
Molecular Pathology
Molecular Biology Principles
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3
Molecular Pathology
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Visualization of heterogeneous ribonulceoprotein particle (hnRNP) protein ! associated with nascent transcripts!
Molecular Biology Principles
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Molecular Pathology
Molecular Biology Principles
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5
Molecular Pathology
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Consensus sequences around 5 and 3 splice sites in vertebrate pre-mRNA!
Molecular Biology Principles
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Molecular Pathology
Molecular Biology Principles
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Molecular Pathology
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DNA: blue! Polyadenylated RNA: red!
Molecular Biology Principles
Splicing protein: green! Polyadenylated RNA: red!
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Molecular Pathology
Molecular Biology Principles
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Molecular Pathology
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The nuclear pore complex!
Molecular Biology Principles
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Molecular Pathology
Molecular Biology Principles
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Molecular Pathology
Molecular Biology Principles
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Molecular Pathology
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A mammalian example!
Molecular Biology Principles
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Molecular Pathology
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Iron-dependent regulation of the stability of transferrin-receptor mRNA!
Molecular Biology Principles
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Molecular Pathology
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Iron-dependent regulation of translation of ferritin mRNA!
Molecular Biology Principles
15
Molecular Pathology
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Introduction of a pre-rRNA transgene induces formation of a new nucleolus!
Molecular Biology Principles
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Molecular Pathology
Molecular Biology Principles
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Molecular Pathology
Molecular Biology Principles
h/p://www.interpathology.org
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