44 4. Kamal-Eldin A, Pettersson D, Appelqvist LA. Sesamin (a compound from sesame oil) increases tocopherol levels in rats fed ad libitum. Lipids 1995, 30:499–505 5. Budowsky P, Narkley KS. The chemical and physiological properties of sesame oil. Chem Rev 1951, 48:125–151 6. Sankar D, Sambandam G, Ramakrishna Rao M et al. Modulation of blood pressure, lipid profiles and redox status in hypertensive patients taking different edible oils. Clin Chim Acta 2005, 355:97–104 7. Hirose N, Inoue T, Nishihara K et al. Inhibition of cholesterol absorption and synthesis in rats by sesamin. J Lipid Res 1991, 32:629–638 8. Sugano M and Akimoto K. Sesamin: a multifunctional gift from nature. J Chin Nutr Soc 1993, 18:1–11 9. Matsumura Y, Kita S, Morimoto S et al. Antihypertensive effect of sesamin. I. Protection against deoxycorticosterone acetatesalt-induced hypertension and cardiovascular hypertrophy. Biol Pharm Bull 1995, 18:1016–1019 10. Matsumura Y, Kita S, Tanida Y et al. Antihypertensive effect of sesamin. III. Protection against development and maintenance of hypertension in stroke-prone spontaneously hypertensive rats. Biol Pharm Bull 1998, 21:469–473 11. Miyahara Y, Hibasami H, Katsuzaki H et al. Sesamolin from sesame seed inhibits proliferation by inducing apoptosis in human lymphoid leukemia Molt 4B cells. Int J Mol Med 2001, 7:369–371 12. Wichitsranoi J, Weerapreeyakul N, Boonsiri P et al. Antihypertensive and antioxidant effects of dietary black sesame meal in pre-hypertensive humans. Nutr J 2011, 10:82 13. Hsu CC, Huang CN, Hung YC et al. Five cysteine-containing compounds have antioxidative activity in Balb/cA mice. J Nutr 2004, 134:149–152 14. Ahmad S, Yousuf S, Ishrat T et al. Effect of dietary sesame oil as antioxidant on brain hippocampus of rat in focal cerebral ischemia. Life Sci 2006, 79:1921–1928 15. Kang MH, Naito M, Tsujihara N et al. Sesamolin inhibits lipid peroxidation in rat liver and kidney. J Nutr 1998, 128:1018–1022 16. Fukuda Y, Nagata M, Osawa T et al. Chemical Aspects of the Antioxidative Activity of Roasted Sesame Seed Oil, and the Effect of Using the Oil for Frying. Agric Biol Chem 1986, 50:857–862 17. Fukuda Y, Nagata M, Osawa T et al. Contribution of Lignan Analoguest to Antioxidant Activity of Refined Unroasted Sesame Seed Oil. J Am Oil Chem Soc 1986, 63:1027–1031 18. Fukuda Y, Koizumi Y, Ito R et al. Synergistic Action of the Antioxidative Components in Roasted Sesame Seed Oil. Food Sci Tech Res 1996, 43:1272–1277 19. Arumugam P, Ramesh S. Protective effects of sesame oil on 4NQO-induced oxidative DNA damage and lipid peroxidation in rats. Drug Chem Toxicol 2011, 34:116–119 20. Bhaskaran S, Santanam N, Penumetcha M et al. Inhibition of atherosclerosis in low-density lipoprotein receptor-negative mice by sesame oil. J Med Food 2006, 9:487–490 21. Calleja L, París MA, Paul A et al. Low-cholesterol and high-fat diets reduce atherosclerotic lesion development in ApoE-knockout mice. Arterioscler Thromb Vasc Biol 1999, 19: 2368–2375 22. De La Cruz JP, Villalobos MA, Carmona JA et al. Antithrombotic potential of olive oil administration in rabbits with elevated cholesterol. Thromb Res 2000, 100:305–315 23. Gorinstein S, Leontowicz H, Lojek A et al. Olive oils improve lipid metabolism and increase antioxidant potential in rats fed diets containing cholesterol. J Agric Food Chem 2002, 50:6102–6108 24. Satchithanandam S, Chanderbhan R, Kharroubi AT, Calvert RJ et al. Effect of sesame oil on serum and liver lipid profiles in the rat. Int J Vitam Nutr Res 1996, 66:386–392 © 2013 Ελληνική Εταιρεία Αθηροσκλήρωσης
Λ-Μ.Α. Κορού και συν 25. Visavadiya NP, Narasimhacharya AV. Sesame as a hypocholesteraemic and antioxidant dietary component. Food Chem Toxicol 2008, 46:1889–1895 26. Biswas A, Dhar P, Ghosh S. Antihyperlipidemic effect of sesame (Sesamum indicum L) protein isolate in rats fed a normal and high cholesterol diet. J Food Sci 2010, 75:274–279 27. Korou LM, Agrogiannis G, Pantopoulou A et al. Comparative antilipidemic effect of N-acetylcysteine and sesame oil administration in diet-induced hypercholesterolemic mice. Lip Hlth Dis 2010,9:23 28. Ashakumary L, Rouyer I, Takahashi Y et al. Sesamin, a sesame lignan, is a potent inducer of hepatic fatty acid oxidation in the rat. Metabolism 1999, 48:1303-1313 29. Sirato-Yasumoto S, Katsuta M, Okuyama Y et al. Effect of sesame seeds rich in sesamin and sesamolin on fatty acid oxidation in rat liver. J Agric Food Chem 2001, 49:2647–2651 30. Jeng KC, Hou RC, Wang JC et al. Sesamin inhibits lipopolysaccharide-induced cytokine production by suppression of p38 mitogenactivated protein kinase and nuclear factor-kappaB. Immunol Lett 2005, 97:101–106 31. Ogawa H, Sasagawa S, Murakami T et al. Sesame lignans modulate cholesterol metabolism in the stroke-prone spontaneously hypertensive rat. Clin Exp Pharmacol Physiol Suppl 1995, 22:310–312 32. Nakabayashi A, Kitagawa Y, Suwa Y et al. alpha-Tocopherol enhances the hypocholesterolemic action of sesamin in rats. Int J Vitam Nutr Res 1995, 65:162–168 33. Chen PR, Chien KL, Su TC. Dietary sesame reduces serum cholesterol and enhances antioxidant capacity in hypercholesterolemia. Nutr Res 2005, 25:559–567 34. Alipoor B, Haghighian MK, Sadat BE et al. Effect of sesame seed on lipid profile and redox status in hyperlipidemic patients. Int J Food Sci Nutr 2012, Jan 23 (Epub ahead of print) 35. Wu JH, Hodgson JM, Puddey IB et al. Sesame supplementation does not improve cardiovascular disease risk markers in overweight men and women. Nutr Metab Cardiovasc Dis 2009,19:774–780 36. Hirata F, Fujita K, Ishikura Y et al. Hypocholesterolemic effect of sesame lignan in humans. Atherosclerosis 1996,122:135–136 37. Mensink RP, Katan MB. Effect of a diet enriched with monounsaturated or polyunsaturated fatty acids on levels of low-density and high-density lipoprotein cholesterol in healthy women and men. N Engl J Med 1989, 321:436–441 38. Dhar P, Chattopadhya K, Bhattacharyya D et al. Ameliorative influence of sesame lignans on lipid profile and lipid peroxidation in induced diabetic rats. J Agric Food Chem 2007, 55:5875–5880 39. Sugano M, Inoue T, Koba K et al. Influence of sesame lignans on various lipid parameters in rats. Agric Biol Chem 1990, 54:2669– 2673 40. Steinberg D, Parthasarathy S, Carew TE et al. Beyond cholesterol. Modification of low-density lipoprotein that increase its atherogenicity. N Engl J Med 1989, 320:915–924 41. Ogawa T, Makino T, Hirose N et al. Lack of influence of low blood cholesterol levels on pancreatic carcinogenesis after initiation with N-nitrosobis(2-oxopropyl)amine in Syrian golden hamsters. Carcinogenesis 1994, 15:1663–1666 42. Ralay Ranaivo H, Diebolt M et al. Polyphenolic compounds from Cognac induce vasorelaxation in vitro and decrease post-ischaemic cardiac infarction after an oral administration. Fundam Clin Pharmacol 2004, 18:331–338 Ημερομηνία Υποβολής 27/7/2012 Ημερομηνία Έγκρισης 15/10/2012