37
Ethno medicine in complementary therapeutics
products. The following are some of the plant derived drugs available in market after the approval of USFDA and few in early stages of clinical trials. The bioactive phytoconstituents derived from ethnic medicine showed the presence of variety of chemical entities, belonging to different classes as represented in Figure 3 and were made available in the market. O O
O
O
O
O
O
HO N
Arteether (1)
Galanthamine (2) F
OH
S
F
O
O
F
N+
O
O
S O
O
-
O
N+
O
Br-
Nitisinone (3)
Tiotropium (4) HO
F F
O
O O
HO
O
N
O
N O
HO
N
OH
O O
NH O
OH
Morphine-6-glucuronide [M6G] (5) NH2
N
HO
O
O
Vinflunine (6)
O O
N
O OH
N
O
HO
O
O
F
O
Exatecan (7)
Calanolide A (8) O O
O
OH O
HO
OH O
O N
Betulinic acid (9)
O
O O
O O
Pervilleine A (10)
Figure 3. Several potent bio-active phytoconstituents from ethnic medicine.