Orange Appeal September/October 2021

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september | october 2021

features

Reconnect & Reengage: 2021 Orlando Women’s Conference Preview & Program

The September 14 event at the Dr. Phillips Center for the Performing Arts will feature more than 30 well-respected community leaders sharing thoughts and experiences on everything from navigating new normals, implementing big changes and prioritizing mental health to creating more opportunities for women and defining success on your own terms. Dr. Keita Joy, Barbara Poma and Rania Arwani will present the keynote sessions.

CHRISTI ASHBY

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Falling for Fashion

Orlando area retailers are ready for autumn, and they share what’s trending and in store for everything from formal galas to casual brunches. ‘Tis the season to dress up again in shimmery, sequined and embroidered gowns, tailored city suiting, flirty, flowy dresses for almost any occasion, and even designer denim. Clear your closet for some fabulous new arrivals from Monkee’s, Tuni, Bloomingdale’s, Neiman Marcus and ShopModa.

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on the cover:

Jennifer Bentson, wearing a Mac Duggal pleated long sleeve gown from Bloomingdale’s, photographed by Christi Ashby in the Personal Stylist Suite at The Mall at Millenia. Story on page 50.

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september | october 2021

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september | october 2021

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10 THE LIST People, places and things: It’s high time to fill your dance card, take your happy hour game up a notch, or just glamorize a girls’ brunch with the prettiest bags; Update your wardrobe by choosing shoes with personality and pizzazz; Women To Watch: Author, esthetician and entrepreneur Tessa Boyd is taking things to the next level; Designer and influencer Ashley Brooke shares her success story in the busy blogosphere; Canine Companions Tales & Tails Gala celebrates its 25th anniversary with a quartet of co-chairs.

26 BEAUTY, BODY & SPIRIT Think Pink… products making a difference in the breast cancer battle; Ask Dr. Deb

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debuts with your questions on a variety of topics for Dr. Deborah Harding; Women Are Incredible: Yamile Luna, Vice President for Organizational Culture and Well-being at AdventHealth, is a career driven, loving mother, devoted wife, community advocate, and her journey with cancer has taught her some important life lessons.

42 TASTES & EXPERIENCES Continue the summer vibe with tiki cocktails crafted at downtown’s Grand Bohemian hotel; Sip and sup on Lake Ivanhoe at The Pinery where the menu and décor pay homage to the site’s sweet past; Eddie Nickell and Nick Olivieri have once again invested in the neighborhood they clearly love with their expanded Bites & Bubbles restaurant and bar.

Orange Appeal makes a great gift any time! Subscribe at orangeappeal.com. Get all the event info by signing up for the e-newsletter or visiting our interactive website. For changes of address, or to cancel or renew your subscription, visit orangeappeall.com/subscribe-to-orange-appeal/. 2

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welcome

I

CLOSET CONFESSIONS know it’s been a strange, strange year and a half, but the other day when I walked into my closet, I heard some whispered conversations that got me quite concerned — my clothes, shoes

and handbags were talking to each other. I guess they had listened to enough of my ruminations about the general anxiety surrounding attending the big events and even the disappointment at not being able to do our annual fall fashion shoot. I was afraid they were going to march out, but that would be a little ridiculous — or would it? From the dress collection it was all moaning and groaning. The pink print said, “I thought I was going to be in regular rotation.” And the orange one responded, “I only get worn at big Orange Appeal parties.” The black one chimed in, “I’m here for funerals and somber occasions so

who cried out, “Everything is about being

but they were divided as well. The large

I guess it’s good I haven’t been out.” Then

comfy. Look how often the flats and blocks

tote bags were catty and explained, “We

the black and white pattern popped up,

and wedges get out of here. They are defi-

will always be in rotation because we hold

“Well, she only wears me, a lot, because I

nitely the favorites now.” But the wedges

everything so stylishly.” But the clutches

am looser and have clever sleeves.” Then

rebutted, “Not all of us! Only the platform

were not having any of it, adding, “It will

there was a general sigh as the formal

ones make it out the door.” And the boots

be our time soon enough and then you big

dresses piped up.

just sobbed at the prospect of missing yet

bags will go in the other closet.” Then

The fuchsia one cried out, “Do you

another fall and winter season. The flip-

everyone gasped, “The ‘other’ closet. That’s

every think we’re getting out of these

flops boasted loudly and proudly as they

the last stop before going to a new home.”

black garment bags? At least we could

showed off their worn soles.

Then things got very quiet, and I gently

mingle with the short ones.” The red one

It went on and on… t-shirts cheered,

was indignant, “I have never even been

and metallic tops jeered, as suddenly it

worn because she was always going to lose

had become a popularity contest where

those 10 pounds.” Then the blue lace one

the 2019 rarely-worns had become the

P.S. We had planned a big fall fashion

with the exposed zipper exclaimed, “Well,

2021 most sought-afters. Pull-on jeans and

shoot on location with models, hair, make-

I might be retired now as I have been

pants claimed, “We’re almost worn out

up, styling, photographers — but then…

worn more than any of you.” The black

and need to be replaced,” while crepes,

So, we visited our fashion partners and

ones just cried at the thought of never

silks and prints exclaimed, “We’re getting

had them show us what’s in for autumn.

being seen again.

dusty and maybe a little musty.”

But the shoes had a lot more to say

I thought at least the handbags would

about their state — especially the stilettos

be in agreement on their neglected status,

Follow us on 4

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@OrangeAppeal

touched each and every one of them, promising to wear them soon.

@appeal_media



EDITOR & PUBLISHER

Christi Ashby christi@orangeappeal.com ASSOCIATE EDITOR & PUBLISHER

Kate Slentz kate@orangeappeal.com MARKETING ASSOCIATE

Wendy Tramell wendy@orangeappeal.com CIRCULATION CONSULTANT

Mollie O’Shea BUSINESS MANAGER

Robert Ashby CONTRIBUTORS

Deborah Harding, MD Rebecca Moroose, MD PRODUCTION DIRECTOR

Rita Tyrrell FOR ADVERTISING:

advertising@orangeappeal.com FOR SUBSCRIPTIONS:

subscriptions@orangeappeal.com

orangeappeal.com Copyright 2021. No materials may be reproduced without permission. Please do not send unsolicited articles or photographs. Publisher not responsible for individual opinions contained herein. Orange Appeal (Permit #201) is published bi-monthly by Appeal Media & Events Group, 1903 Michael Tiago Circle, Maitland, FL 32751. Printed in USA. Standard postage paid at Harrisburg, PA and additional mailing offices. POSTMASTER: Send address changes to Orange Appeal, 1903 Michael Tiago Circle, Maitland, FL 32751 6

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connect! MAIL

Make sure you receive your issues of Orange Appeal right in your mailbox. If you haven’t signed up in the past six months, please visit orangeappeal.com/subscribe and click on the special offer. Please send change of address info to subscriptions@orangeappeal.com. Interior Appeal will be sent to you three times a year with your subscription!

EMAIL

Sign up at orangeappeal.com for the Orange Appeal e-newsletter, delivered to your inbox at least twice monthly. Keep up with community and charity events! For advertising info, email: advertising@orangeappeal.com To submit events, email: events@orangeappeal.com

EVENTS The 11th annual ORLANDO WOMEN’S CONFERENCE will be held Tuesday, September 14, at the Dr. Phillips Center for the Performing Arts. For updates and details, visit orlandowomensconference.com. For sponsorship information email kate@orangeappeal.com. MONTHLY LADIES LUNCHEONS are on summer hiatus but will return in the fall. For more information about all the Orange Appeal events, visit the Orange Appeal Facebook page.

SOCIAL MEDIA

ORANGE APPEAL Tag, share and follow… check out all the event photos and latest info.

@APPEAL_MEDIA Get behind-the-scenes peeks!

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thelist party pretty Ready to fill your dance card, take happy hour up a notch, or just glamorize a girls’ brunch? Take inspo from these dazzling designer bags to add some sparkle to your post-athleisure style. Top to bottom: VERSACE Mini Medusa studded suede top handle bag; CHRISTIAN LOUBOUTIN Elisa baguette bag in patent leather; ROSANTICA Holli embellished top handle bag; and MARY FRANCES Champagne On Ice top handle handbag (available locally at ShopModa).

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thelist

chooseSHOES! Get your groove on with these polished pairs. They offer pretty great excuses to kick off the sneaks and show off your dancing queen moves. CHRISTIAN LOUBOUTIN Ruban mock-croc stiletto red sole sandal

AMINA MUADDI Gilda suede and crystal sandal

LOUISE ET CIE Fionnah chain-strap mule BADGLEY MISCHKA Bohemia embellished pump

LOUISE ET CIE Lakma cage pump

TOM FORD metallic lizard-print Lock sandal

VERSACE Medusa crystal satin slingback pump

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thelist

chooseSHOES! DRIES VAN NOTEN Velvet Rose square-toe pump

VERSACE Safety Pin lamb sandal

VALENTINO GARAVANI French Bows patent gladiator pump

AQUAZZURA Le Parisien metallic slide sandal

MANOLO BLAHNIK Lurum crystal cocktail mule SOPHIA WEBSTER Rosalind glitter sphere-heel sandal

SAINT LAURENT Opyum YSL logo-heel sandal

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thelist WOMEN to WATCH

TESSA BOYD:

UNDENIABLY UNSTOPPABLE Businesswoman, author, entrepreneur, teacher, coach and esthetician Tessa Boyd always believed in her dreams for a career and life — and with her Elise Esthetics Institute, they are coming true.

S

he graduated from the Univer-

position or risk having reduced hours. It

sity of Cincinnati with a business

was not something I wanted initially, but it

degree specializing in market-

led me into the director of education posi-

ing and management and started

tion for the school. I was responsible for

her professional life in the city.

building the team,” she explains. Unfortu-

“I decided to change my career and

nately, that involved firing some long-term

become a licensed esthetician. I got to a

employees. She was also charged with

point in Cincinnati where the weather

growing the school, but she found herself

really got to me. It turned me into a not-a-

no longer believing in its vision. It led to

nice person. So, in 2006 I decided to move

an a-ha moment — sitting outside on a

to Orlando — I felt it could be a great place

green bench pondering — after she was

for me to catapult as an esthetician

led to believe she would be promoted to an

because the business would not be so

exciting new position and then found out

purpose-driven life. A lot of people would

cyclical. In Ohio, people typically got

someone else had been hired.

say to me, ‘I would be an esthetician if…’ I

facials in the winter but not really yearround,” she says.

Armed with experience, education,

decided what if I could take the ifs out of it

enthusiasm and drive, Tessa decided to

with a school that was conducive to every-

She moved here by herself and trans-

start her own school. “I wanted to have a

one’s schedule. I have the first online

ferred with her employer, Sephora, to

school that was different. I am a firm

hybrid skincare program in the state of

start over. “I knew when I moved here, I

believer in purpose and living out your

Florida,” she says.

wanted to get into education. I had this

In getting to this point, Tessa had to

love for aesthetics, but I also had this love

prove to the licensing governing body that

for educating people,” she adds.

there was a need and that it could work.

Sephora had a program at the time

“The interesting thing about this journey

where Tessa was able to train other

is I have never attended an online class. I

employees. She thought she had found her

went to traditional in-person classes. We

dream position, but the door quickly

presented to the commission and got

closed due to corporate policies. She found

approved in September 2011 and were

a local college that offered courses in skin-

scheduled to start a class in January 2012,”

care and massage therapy and was able to

she explains.

start teaching skincare.

There were three students enrolled but

“It was one of the first times in my life

not one of them started. “That February I

where I felt like I got up every day and just

was in the fetal position wondering what I

played. It was the most fulfilling job ever. I

was going to do now. I had to reset my focus

got to train people to do what I do. But

while I was working some part-time jobs.

after a couple of months, I was told they

By September 2012 I had more people that

were going to cut my teaching hours so I

were interested and began the first pro-

could either get back into a management

gram with two students,” she shares.

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thelist WOMEN to WATCH Tessa sacrificed her more comfortable

ing her own building so she can expand

lifestyle in the beginning, actually living

the school. “We want to add to our pro-

in the school space with a Murphy bed

gram offerings and really be more all-

that pulled down at night. “For three and a

encompassing, going beyond skincare. In

half years I lived in my business. One time

our current space we have a waiting list

I forgot to lock the door and my banker

because we are limited in terms of how

came in while I was undressed. I look

many students we can have. In addition to

back and think those were some of the

training, we want to make sure our stu-

best years of my life because for the first

dents are marketable so they can go out

time I felt like I took control and was in

and get jobs,” explains Tessa, who has

charge,” she says.

been happily married since 2014 and cred-

Ten years later, Tessa has exceeded her dreams and is in the process of purchas-

its her husband with supporting her vision.

EXCERPTS FROM THE CLASSY HUSTLE KEEP YOUR WORD “I woke up one Monday morning fatigued and irritated because I had not been able to say no to an invitation to a birthday party. In saying yes to the invitation, I chose to honor someone else instead of the commitment I made to myself to keep Sunday as my day of rest and relaxation, as this is the only day I do not work. For the rest of that week, I paid for my decision. My week was a blur, and my thoughts were clouded. And then it dawned on me that I had not rested. There are times that you have to say no to invitations so that you can rest.”

DARE TO BE DIFFERENT “You have to be content with being alone. Dare to be different. As I reflect back, even at a young age, I was very different. I dared to ask pensive questions, even at the expense of offending others. I was on a quest for knowledge, and I wanted to know ‘the whys’ behind things. Even today, when I coach, train and teach others, I always find myself answering ‘the whys.’”

FIND YOUR VALUE AND WORTH “I struggled for years in knowing my value and worth. I wanted acceptance from others, and I wanted to fit in. Because I was ‘a little different’ I defined my worth as others saw me. I had limited beliefs in what I was capable of achieving. By putting in the work, I started to peel the layers off the onion. The outer layer represented how I wanted others to see me. I peeled that layer off. The next layer represented how I really saw myself, that part was a little painful. I realized that I received negative words spoken by other people. This wasn’t really who I was, it was what I accepted as truth, so it was a lie. I denounced those lies. I was left with the core of the onion, which represented who I really was.” The Classy Hustle, by Tessa Boyd, is available on Amazon. Tessa will be on one of the panels at the Orlando Women’s Conference on September 14. 18

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thelist WOMEN to WATCH

Ashley Brooke: Designed to Pivot POPULAR DESIGNER AND

adds. She ended up expanding from sta-

INFLUENCER ASHLEY BROOKE

tionery into hard desk items including

was fresh out of college with a degree in

notepads, tumblers and coffee mugs, mov-

interior design and planned a career in her

ing into the wholesale arena. During this

chosen field, but it was 2008. “When I grad-

period Ashley met her future husband

uated it was right when the market crashed

who also had blogging experience.

and I found myself without a job. I had got-

“He asked me why I was blogging five

ten a first job but was immediately laid off

days a week since there was no direct rev-

within two weeks. The downturn was really

enue coming from it. I told him people

tough on the design industry,” she says.

were buying product after reading the

So, Ashley moved back home to Bre-

blog. He convinced me that there was no

vard County where her parents had estab-

reason why the blog itself shouldn’t be

lished a thriving photography business.

making money,” she explains. That’s when

“My dad had a couple of studios and he

the big shift began. By 2016, after they had

generously hired me as a retouch artist.

been married a few years, and the prod-

He taught me Photoshop and it made me

ucts were in more than 700 stores world-

realize I truly wanted to do something in a

wide, the blog became a stand-alone busithe blog started getting traction, I started

ness. Ashley’s husband quit his job to join

While her parents encouraged her to

getting comments from people wanting to

her and expand both platforms, but by

continue exploring creative careers, she

know where my shirt was from or what

2017 they decided to close the product side

says it was really a season for her to find

color lipstick I was wearing — questions

and focus solely on the blog.

out who she wanted to be. Her first foray

that went beyond paper products and sta-

creative industry,” she adds.

came from necessity — it was after her

tionery,” she explains.

“I was stretched very thin doing both things. I was not as excited about where the

birthday, and she needed stationery to

Ashley began adding more lifestyle

product industry was going. The margins

send thank you notes. “Since I had this

content to the blog while growing the sta-

were getting smaller on the products we

new-found Photoshop skill plus my art

tionery business. As demand grew, she

made. It almost felt like we were paying to get

background, I started doing these little

was able to make stationery her full-time

our products in the big box stores,” she says.

doodles and scanning them in. I fell in

job. “I looked at the blog as a funnel for the

Ashley credits her beginnings during a

love with paper and realized I had mar-

business. But as it expanded, I got to talk

recession with helping her realize that

ried all my favorite things,” she explains.

about more of my favorite things — things

sometimes you have to move in a different

that you would find on Pinterest now,” she

direction depending on the economy, sea-

That’s when she became a stationery designer and spent time reading business

son and demand. “Our No. 1 word is pivot.

books and studying how to start and man-

And it’s about not holding onto things too

age her own small business while still

tightly,” she adds. As they continued with

working fer her parents. One of the books

the blog, Ashley’s husband took another job

she took to heart was New Rules of Market-

and it allowed her to build a team to run it.

ing and PR which advised starting a blog.

“The blog has changed a million times

“This was at a time when most people did

over and it’s changed due to what our

not even know the word. I was intrigued

readers want. That’s the biggest lesson —

by the idea, especially since I had no money

sometimes things I think will work are

for advertising. So, I had a little website

not necessarily the things that do work best.

designed. I launched it and published my

I want to give the audience what they want

first daily blog the same day. I talked about

— to be their best friend or big sister they

subjects related to paper and then once a

didn’t know they needed. It’s all about cre-

week I would talk about my stationery. As

ating a community,” she explains.

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thelist

Canine Companions Tales & Tails Gala Celebrates 25th Anniversary On an 8-acre campus off Clarcona Ocoee road resides the Southeast Region Training Center for Canine Companions, a national organization that trains and provides service dogs to people with disabilities. The state-of-the-art facility serves the states of Florida, Georgia, Tennessee, North Carolina, South Carolina, Mississippi, Alabama and Louisiana. While the training center opened just over 21 years ago, the organization’s signature fundraiser, Tales & Tails Gala, will celebrate its 25th anniversary on October 23 at Rosen Shingle Creek with an in-person event, as well as an exciting virtual live stream experience. We caught up with the gala co-chairs to learn more and find their reasons behind volunteering for this beloved organization and event. Robin Sanchez: Supporting Canine Companions was an easy decision after I attended a graduation ceremony. By the end of the weekend, I had decided I wanted to be part of an organization that changes lives. I have been involved with the Tales & Tails Gala for the past 15 years and I am also a volunteer puppy raiser.

Paul Richards: I knew a little bit about the mission but decided to become more involved and joined the Tales & Tails Gala committee in 2004. I continued to be involved after meeting a mother and her daughter who had just been matched with one of our service dogs. She told me their dog had been one of the biggest blessings and gifts they had ever received.

Trish Walsh: When I learned from friends how much independence and love these dogs bring to people with disabilities, I knew I had to become involved. And it didn’t take me long to recognize the tremendous positive impact that Canine Companions has and I tell everyone that being involved with Canine Companions brings a smile to my face every day.

Mary Taylor Jacobs: I raised my first puppy in 1993 after

Robin Sanchez, Paul Richards, Trish Walsh and Mary Taylor Jacobs

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learning about the organization through my involvement with the General Federation of Women’s Club. Supporting Canine Companions and the Tales & Tails Gala is a way for me to help others and is part of my personal commitment to benefit the community.



ORANGE APPEAL: The Tales & Tails Gala is celebrating its 25th anniversary — what gives it such longevity?

OA: Events are finally back after more than a year — what can guests expect? Anything new or different?

OA: How was the organization affected by the pandemic? Any new programs or innovations that came from it?

ROBIN SANCHEZ: From its humble

PAUL RICHARDS: Last year when

beginnings, this fundraising event has

COVID changed our fundraising world,

TRISH WALSH and MARY TAYLOR JACOBS: 2020 was an unprecedented

risen to prominence as one of Central

it allowed us to try new things and the

year for everyone and especially for

Florida’s premier charity events — setting

heart, brains and courage of Canine

non-profit organizations. The uncertainty

records for both attendance and monies

Companions came to life on computer and

and demands of the pandemic made us

raised. The incredible success of our

television screens when the Tales & Tails

worry — but we also realized it was a

event is the result of the hard work and

Gala was presented virtually and still set

time of opportunity, a time to reimagine

dedication of numerous volunteers, gala

fundraising records — raising more than

who we are, and a time that would make

committee members and key partner-

$600,000. This year we are thrilled to

us better in the process — and the

ships. And our guests and sponsors

gather together for an in-person event

pandemic certainly did not slow us down.

return after hearing amazing stories from

while taking safety measures to protect

A disability doesn’t disappear in time of a

our clients about how their service dogs

the well-being of everyone. But we will

crisis and neither did Canine Compan-

have impacted their lives and helped

also offer a live stream experience like

ions — its mission continued. They

them be independent. And there are

none other, and participants will have the

adapted and established safety measures

adorable puppies everywhere!

choice on how to attend. Guests in-person

including remote work, socially distanced

will enjoy silent and live auctions, a

Team Trainings, online events, a shift to

cocktail hour, a delicious gourmet dinner,

digital communications, and more.

To learn more about the upcoming Tales & Tails Gala visit canine.org/galacelebration

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service dog demonstrations, live music, and amazing inspirational stories.


september | october 2021

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beautybody&spirit pink products Shop and support breast cancer causes and organizations with these pretty items (clockwise, from top left): ili New York Beauty leather train case, $69, ilinewyork.com, 10% of proceeds benefits the Breast Cancer Research Foundation year round; Kendra Scott Metastatic Breast Cancer necklace charm set in rose gold, $110, kendrascott.com, proceeds support the company’s Inheritance of Hope Legacy Retreat for families with a parent battling metastatic breast cancer; Kendra Scott Rose Quartz small votive candle, $22, kendrascott.com, every purchase supports a woman undergoing cancer treatment with a gift of jewelry and a handwritten note; TELETIES In Memory of Ida large hair ties, $15, teleties.com, proceeds from the purchase of all TELETIES benefits the nonprofit FORCE (Facing Our Risk of Cancer Empowered).

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beautybody&spirit

Making Progress in Personalized Breast Cancer Research and Treatment by Rebecca Moroose, MD,

Director Cancer Clinical Trials, Director Cancer Genetics, Orlando Health UF Health Cancer Center “Innovation drives progress” is the mantra of the FDA’s Center for Drug Evaluation and Research (CDER). Each year, CDER publishes a list of new drug approvals. Multiple new agents with novel mechanisms of action have been approved for treating early- and later-stage breast cancer in recent years and some breast oncologists refer to this plethora with the idiom “an embarrassment of riches” from a 1726 French comedy. This idiom connotates an overabundance of something or “too much of a good thing.” I consider this plenitude an “abundance of blessings” paving the way to treat each individual’s breast cancer with therapy more specific to his or her tumor and less toxic to the system. AS A REMINDER, treatment of breast cancer used to be a “one-size-fits-all” approach — typically surgery, chemotherapy, sometimes radiation therapy, and often anti-hormonal therapy. With the advent of the Human Genome Project and better understanding of genomic and biological mechanisms of disease, scientists can iden-

ER+ PR+ Her2+ = both endocrine and Her2 positive breast cancer, also called triple positive, that can be approached with anti-hormone therapy as well as Her2 directed therapy. ER- PR- Her2+ = Her2 driven cancer that is amenable to Her2 directed strategies.

Some of the significant innovative treatments for breast cancer approved by the FDA in the last few years include: • Margetuximab-cmkb — a monoclonal antibody to treat patients whose tumors overexpress the HER-2neu receptor. This novel antibody has been

ER- PR- Her- = triple negative breast cancer (TNBCV) which traditionally was dependent on chemotherapy for treatment until new breakthroughs in immunotherapy and antibody drug conjugate treatments were developed.

engineered to bind to Her2 positive

gesterone hormone receptor (PR), and the

The subclassifications of breast cancer

• Fam-Trastuzumab deruxtecan-nxki

Her2neu receptor (Her2). The presence or

continue to expand and use of genomic

— is an antibody-drug conjugate. The

absence of these receptors allows subclas-

testing aids in our understanding of pre-

antibody is directed to the Her2

sification of breast cancers which we call

dicting treatment responses or providing a

receptor and carries a toxic payload of

the cancer “phenotype:”

prognosis. Studying the acquired genomic

chemotherapy that is released into the

alterations in cancer cells also leads to a

tumor, generating less toxicity to the

molecular signature that may be exploited

patient compared to giving chemo-

with targeted therapies.

therapy alone.

tify the molecular hallmarks of cancer and design treatment specific for those aberrations. We currently evaluate the status of three receptors on breast cancer cells: the estrogen hormone receptor (ER), the pro-

ER+ PR+ Her2- = endocrine (anti hormone) sensitive breast cancer that is Her2 negative. 28

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cells and to help activate the immune system to enhance antibody dependent cell-mediated cytotoxicity against tumor cells.



beautybody&spirit • Sacituzumab-govitecan-hziy — this is

develop breast cancer due to an inher-

surveillance and clearance of the

another antibody drug conjugate that

ited mutation in BRCA1 or BRCA2.

tumor is enhanced. The VENTANA

was first approved for triple negative

These drugs are polyADP ribose

PD-L1(SP142) laboratory assay must

breast cancer and targets a common

polymerase (PARP) inhibitors and have

be used to identify patients who are

protein on cancer cells (TROP-2) and

proven successful in inducing lethal

candidates for this treatment.

carries a potent chemotherapy payload

damage to tumor cell DNA when the

into the tumor cell.

BRCA1/2 proteins are dysfunctional and

• Two oral small molecule inhibitors have also been approved for treating Her2+ breast cancer: • Neratinib — an oral small-molecule irreversible inhibitor of Her2 and members of this receptor family (EGFR1 and Her4)

cannot repair the damage. This process is known as synthetic lethality and takes advantage of the dysfunctional BRCA1/2 DNA repair pathways in the tumor cells with less toxicity to normal tissue. • Atezolizumab — approved for patients with advanced/metastatic triple

• Tucatinib — an oral reversible

negative breast cancer in combination

small molecule inhibitor more

with chemotherapy in patients whose

selective for the Her2 receptor that

tumors express the PD-L1 protein.

has been shown to treat systemic

PD-L1 is the programmed death ligand

disease and active brain metastases.

1 which when present blocks the

• Olaparib and talazoparib — for patients who carry a genetic predisposition to

patient’s immune system from identifying and attacking a tumor. If PD-L1 is blocked the immune system

• Pembrolizumab is another PD-L1 inhibitor approved in combination with chemotherapy for unresectable or metastatic TNBC in conjunction with chemotherapy in patients whose PD-L1 status is determined by Dako laboratory’s immunohistochemistry test 22C3. • Cyclin-D kinase 4/6 inhibitors comprise a new class of drugs, including abemaciclib, palbociclib, and ribociclib — oral small molecular inhibitors that help to stop cancer cells from proliferating in patients with ER+, PR+, Her2- unresectable or metastatic breast cancer in conjunction with anti-hormone therapy (abemaciclib also has been studied as a single-agent therapy). • Alpelisib — approved in 2019 for patients whose metastatic tumors have an acquired mutation in the PIK3CA gene. Mutations in this gene lead to a defect in a protein called P110alpha. P110a controls cellular growth and division and, when defective, contributes to uncontrolled cell growth. Alpelisib inhibits the defective PIK3CA to reduce its activity. It is currently used for patients whose tumors are ER+/PR+/Her2neu- with a PIK3CA mutation. This is by no means an exhaustive list of the tools we have in our armamentarium to treat breast cancer. Many of these new agents are also being studied in earlier stages of breast cancer and in different breast cancer phenotypes. A pipeline of agents is currently under investigation to improve our success in controlling or, in some cases, curing breast cancer. This is no embarrassment of riches!

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beautybody&spirit

Ask DOCTOR DEB with Deborah Harding, MD, Harding Medical Institute

In this new series, Dr. Deborah Harding will answer readers’ health questions. I have seen a lot of ads lately for collagen supplements. What do they do, and do they really work?

instance, ongoing data shows it can help

I am excited to hear that collagen is finally

lubrication, connective tissue maintenance,

receiving the attention it deserves. Before

and healthy hair, skin and nails. If you

your body. The collagen supplement I per-

collagen supplements were “trendy,” I

exercise frequently, have had any sort of

sonally reccomend is made up of Type 1 and

started

my

injury, have lost weight and worry about

‘Type 2 collagen from high-grade raw mate-

patients years ago — due to the thorough

skin elasticity, or want to help maintain

rials, with scientific clinical trials to back its

and impressive scientific data on collagen

plump skin — collagen is something you

effectiveness. This specific form of collagen

supplements. Collagen is one of the body’s

should be considering taking daily.

can support the healing process, rather than

recommending

them

to

support things like: tendon and ligament self-repair, stem cell rejuvenation, joint

building blocks. It helps with the healing

However, finding a high-quality collagen

simply (and temporarily) block joint pain or

process, muscle tone, skin rejuvenation,

supplement is very important. Many over-

discomfort. I take a collagen supplement

anti-aging, and much more. Taking a col-

the-counter products are a blend of different

daily; I like to use it in the powder form as an

lagen supplement can be a great addition

ingredients and fillers. You want to research

easy addition to my smoothies or morning

to your routine for many reasons. For

the specific ingredients you are putting into

tea or coffee.

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During the pandemic I neglected my annual appointments and exams. What should be my first priorities?

over the course of a few months or the

1 There are many “diet fads” that come

year so you can mark off as you schedule

and go. However, the regimen I always

them. As you see different doctors and

see to be most successful across-the-

I suggest having your annual physical

they refer you to have any additional test-

board is going back to the basics: a

done first so you can get updated lab work

ing or procedures done, you can keep add-

healthy diet with lower sugars, less

and testing, can get a baseline on where

ing to your list and keep your appoint-

processed carbohydrates, and a good

all your numbers are, and can set some

ments organized.

exercise plan. At a minimum, it is

goals with your physician. During this

In the meantime, make sure to keep

important to get in your steps each day

appointment, also discuss if there are any

taking your vitamins and supplements,

(I aim to take at least 10,000 steps daily

routine screenings you may be due for (or

eating heathy, and getting back on a good

for my body). I also suggest two days a

missed), such as a mammogram, pap

exercise regimen!

week of some sort of strength training. Try to come up with fun ways to

smear, skin cancer screening, ultrasound,

exercise that could be good for the

the pneumococcal vaccine, shingles vac-

I want to lose 15 pounds but am so confused about diets and everyone seems to have a different opinion. Which ones do you recommend?

cine, hepatitis A and B vaccine, tetanus

You are right, there are so many options

sport such as tennis, golf or running.

booster shot, etc.) You do not usually need

out there and it can be overwhelming.

an appointment for these. Additionally,

Ultimately, you have to find what will

any procedures or appointments you had

work best for you, your lifestyle, and your

often find success with is incorporating

put on hold during the pandemic should

unique body! Here are my top three “go-to”

healthy smoothies into their day. A good

get scheduled. Try to make a checklist of

tips for dropping those stubborn last 15

tip is replacing one meal a day with a

all the items you would like to get done

pounds that I tell my patients about:

protein smoothie. (Some of my patients

etc. Get those on the books ASAP. Also, plan to head to your local pharmacy if you are due for any immunizations (such as

whole family as well. Some ideas include: a nature hike, an outdoor scavenger hunt, or even taking up a new

2 Another favorite routine my patients

september | october 2021

33


beautybody&spirit eventually replace two meals a day with

each day, instead of the traditional 10-12

smoothies). Then, have your final meal

hours per day.

be a sensible dinner. Your smoothie should consist of a liquid “base” such as water or milk. I personally enjoy using a milk substitute such as almond milk, cashew milk or oat milk. Next, add high-quality ingredients including plenty of vegetables, and a handful of fruits into your smoothie — if possible, try to use organically sourced ingredients. Finally, add a protein source into each smoothie. (In addition to whey protein, there are some great protein powders made from ingredients like egg whites, brown rice and green peas—something for everyone!) Most importantly, to be considered a “meal,” make sure it contains enough protein for your body type.

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3 A lot of my patients are loving Zerona®

To your best health!

fat loss laser treatments for body contouring and stubborn fat. This is the first laser specifically designed for body contouring and fat reduction with NO bruising, swelling, freezing or downtime! You can easily have a treatment on your lunch break and head back to the office after a quick 40-minute session. The best part is you can target the area (or areas) you are looking to specifically treat, such as “spot treating” your inner/outer thigh, abdomen, back, etc. While this laser has given my patients much success, you must continue to incorporate your healthy diet and exercise plan to maximize your results.

Deborah F. Harding, MD, is board certified in internal, sleep disorder and anti-aging medicine. The Harding Medical Institute is located in MetroWest. Learn more at

Another success I often see with my

No matter what method you choose, always

hardingmedicalinstitute.com. If you have

patients is intermittent fasting, where

remember to stay hydrated and get a good

a question for Dr. Deb, email it to

you eat in a smaller window of time

night’s rest.

kate@orangeappeal.com.

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beautybody&spirit

women are incredible!

AN ADVENTHEALTH FOR WOMEN SERIES

YAMILE LUNA:

Lessons Learned through Cancer Journey Yamile Luna is like most of us — career driven, loving mother, devoted wife, community advocate — but her journey with cancer has taught her some important life lessons about success and self-awareness. It makes her acutely qualified for her role at AdventHealth as Vice President for Organizational

H

Culture and Well-being.

er responsibilities include lead-

the healing ministry of Christ and it very

struction. “I was out of commission for

ing the wellness team for the

much resonates with my personal beliefs.

about a year, but being the superhero that

Central Florida Division, which

It’s easy to be authentically yourself every

I thought I was, I continued to work. I

encompasses 16 hospitals, med-

day when you come into a place that is

remained as a vice president but worked

ical offices, Centra Care facili-

more than just a job,” she says.

part time,” she explains.

ties and AdventHealth University. “I over-

She appreciates the team members she’s

About 10 months after she returned to

see employee wellness from the benefits

gotten to work alongside — many who

work full time, she started having severe

side all the way to programming that we

stepped up during her battle with breast

headaches. She thought she had a brain

do on our campuses,” she adds.

cancer. “I was diagnosed in October of

tumor, but it was actually a tumor that

This includes caring for AdventHealth

2012. I was actually leading the [Florida

was wrapped around her heart and in the

employees in mind, body and spirit —

Hospital] Cancer Institute at the time, along

middle of her chest. Determined inopera-

from connecting them with chaplains and

with other areas. It was a very surreal expe-

ble, Yamile went through another round

nutritionists to more importantly and

rience because of the work and programs

of chemotherapy, a new experimental

most recently, mental health services.

we were setting up to help other community

treatment for this type of tumor. “I told peo-

“Through the pandemic, it’s obviously been a huge toll on the mindset of our employees. We actually have licensed mental health practitioners as well as our wellness teams out in the units,” she explains. Throughout her 37 years with AdventHealth, Yamile has held multiple leadership roles. “I tell people I started when I was 5,” she laughs. But she explains that she is proud to be a second-generation

ple the good news is I knew what was going

Even when our careers are on the rise and we feel like we can do everything, we’re not superheroes. We think we are, but we must make sure that we are not only taking care of ourselves but realizing success is more than just a title at work.

team member — both her parents retired from the company — and now her daughter

and team members,” she shares.

to happen and the bad news is I knew what was going to happen,” she says. “I did decide in my second go around that I would take the time off. I learned from my first time that while I was trying to be all things to all people, I recognized that the bad days were spent with my family — I was sick as a dog, and they would care for me — and the good days I spent at work. And I was like, there’s something wrong with this picture, right? I love the fact that I was able to step back and put

and son are third-generation employees.

Her mammogram revealed a stage III

Oh, and her husband has been with the

aggressive tumor in her right breast and

Yamile shares that she continues to

company for 38 years as well.

my family first,” she says.

Yamile opted to have a double mastecto-

receive chemo treatments on a regular basis

“What has kept me with AdventHealth

my. She then went through chemotherapy

and feels very blessed to be in this position

is our mission. Our mission is to extend

(hair loss included), radiation and recon-

where she can affect others with her story.

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beautybody&spirit As a speaker at the Orlando Women’s Conference, she will be elaborating further on her journey as well as providing some practical takeaways for women to better care for their minds, bodies and souls. “Even when our careers are on the rise and we feel like we can do everything, we’re not superheroes. We think we are, but we must make sure that we are not only taking care of ourselves but realizing success is more than just a title at work,” she reflects.

OCTOBER IS BREAST CANCER AWARENESS MONTH Join AdventHealth for its Ninth Annual Pink on Parade 5K on October 10. Together, let’s support community members through their breast cancer journey. Visit PinkOnParade.com to register.

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WHAT IS A WOMEN’S HEALTH NAVIGATOR? A health navigator is a specially trained registered nurse whose job is to make life easier for each and every woman through expert clinical assistance and educational, emotional and spiritual support. All calls are confidenJanelle Grall, tial; anyone can self-refer; and insurance is Doreen Forsythe, BSN, RN BSN, RN, CPN not required to talk or meet. AdventHealth for Women’s health navigators provide complimentary services that help you coordinate your overall care and answer any questions you may have. These services include:

• Finding a care provider • Answering your health care questions • Assistance with scheduling annual office visits and screenings • Resources and support for you and your family • Coordination of care among multiple providers and facilities To contact the Health Navigation Team, call 407-720-5191 or visit HerHealthNavigator.com





tastes&experiences tiki time The chill vibe of summer doesn’t have to be over quite yet. If you need a little tropical thrill to conjure up those surf side scenes, head over to the Grand Bohemian hotel downtown for some refreshing sippers available through the end of September. Tiki cocktails include the Original Hemingway Daiquiri (Captain Morgan white rum, maraschino liqueur, grapefruit and lime), Honi Honi (Bourbon Mai Tai with Bulleit bourbon, triple sec, orgeat and lime), Zacapa 23 Old Fashioned (Zacapa 23 rum, allspice dram, orange and Angostura bitters), Hawaiian Sunset (Ketel One vodka, lemon, lime, grenadine and orgeat), The Matador (Don Julio blanco tequila, pineapple, lime and Angostura bitters) and Jungle Bird (Captain Morgan spiced rum, Italian aperitif bitters, pineapple and lime). 42

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tastes&experiences

THE PINERY: SIP &SUP on the LAKE

by Christi Ashby

Since the opening of Russell’s last year, the story of the land surrounding Lake Ivanhoe has become common knowledge. Who would have guessed a pineapple farm graced the shoreline? The addition of the Lake House apartment high-rise created a scenic space for The Pinery, a restaurant paying homage to the land’s rich past.

O

wner Carol Holladay, who

filling the seats, and we perused the food

many may remember from

options deciding on Cedar Key Clams

her long career at The Tap

(roasted garlic citrus butter, white wine

Room at Dubsdread, has

and lemon) and Fire Roasted Corn Fritters

created a warm and invit-

(arugula, roasted poblano aioli, chives, cotija

ing ambiance anchored by a bustling bar

cheese and red bell pepper) from the Social

and a cozy main dining room inside and a

Eats section. Another interesting item,

welcoming patio outside.

although maybe not so shareable, is the

It had been open for weeks before we

Smoked Peanut Soup (spinach, smoked

had a chance to pop in and we had been

peanuts, sweet potato, broth and micro

warned that the new hot spot fills up

cilantro). We saw several plates of wings

quickly. Arriving about 4:30pm (it opens

and charcuterie boards (The Pinery Platter)

at 4) we quickly found seats at a bar high-

coming out.

top for two and were greeted by one of our

Although we wouldn’t be staying for

favorite bartenders who formerly worked

dinner, we had ample time to review the

at Hillstone. After reviewing the drinks

dishes under the other headings. Among

menu, we ordered cocktails — Pretty in

the notable entrees are Braised Short Ribs

Pink (Hangar One Buddha’s Hand citron

(chimichurri, honey roasted sweet potato

vodka, orange, lemon and strawberries)

and broccolini); Seafood Stew dressed

and Prosecco Watermelon Margarita

tableside (jumbo shrimp, fresh seasonal

(Corazon Blanco tequila, Cointreau and

fish, Cedar Key clams spicy tomato broth,

prosecco) — from the impressive lineup.

Congaree and Penn grit cake); and Florida

As we sipped, the expected crowd started

Grouper dressed tableside (pecan crusted,

beurre blanc, honey roasted sweet potato and brown butter charred Brussels sprouts). There are also salads and sandwiches along with a robust list of sides, and the restaurant sources from local Florida farms. Happy Hour features half-off glasses of wine which is always welcome. Although not yet announced, we got a tip that weekend brunch is on the way.

The Pinery 295 NE Ivanhoe Blvd., Orlando 32804 407-377-7576 | thepineryorlando.com 44

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tastes&experiences

Bites&Bubbles Makes a Move As longtime local restauranteurs (Funky Monkey, Prickly Pear and Nick’s Italian Kitchen) the bona fide OGs of the Mills50 District (Bananas Modern Diner and Restaurant ASH) Eddie Nickell and Nick Olivieri have once again invested in the neighborhood they clearly love.

A

Eddie Nickell and Nick Olivieri

fter selling their Bites & Bubbles building, which was an intimate space that could only seat 44 in total, they moved into a

larger site just down the road. As Nick explains, “We can now seat 44 in the dining room and bar, 44 on the patio, and 44 on the rooftop lounge.” The duo invested in upgrades after the building sat empty for a year, putting their personalities into décor and ambiance, in addition to the French-inspired menu. It’s not surprising considering Eddie has a background in French cuisine at fine din-

Now open at 5pm every day but Sunday,

boards that are carefully put together from

ing establishments, but they do have their

they hope to announce weekend brunch

guest selections of more than 20 offerings

own idea of what constitutes a French res-

soon.

plus appropriate accompaniments. Among

taurant and it’s definitely not a stuffy, white-table cloth atmosphere.

Starting with cocktails, the eclectic list

the notable appetizers are Duo of Pâté and

offers a variety of quenchers. The most

Mousse Truffée (pork and chicken liver

“Back in the 1960s most Americans

unusual may be the Blueberry-Acai Haze

mousse with truffles). The entree menu

claimed they didn’t like French food, but

with Eleven vodka, Quatreau Blueberry-

features their World-Famous Duck Fat

many of the restaurants they were going to

Acai CBD sparkling water, muddled blue-

Burger — two duck fat-infused beef pat-

had French chefs, so the dishes were actu-

berries and mint topped with Martha

ties, Swiss cheese, field greens, tomato

ally inspired by French cuisine and meth-

Stewart CBD gummies. But Nick claims

and special sauce on a brioche bun with a

ods,” he says. They call their style a French

one of the best is their take on the espresso

side of crispy fries.

Kiss, so it’s about an influence and the

martini — Love You a Latte with Absolut

It’s a welcome change to see local res-

ingredients (yes, there is escargot, but it’s

vodka, coffee liqueur, fresh-brewed Kimbo

taurants expanding in this still uncertain

presented out of the shell with brandy

Italian espresso and nutmeg. There’s even

period and supporting them is always a

mustard crème sauce) without pomp or

a local namesake, the Leu Gardens Collins

good idea.

pretense.

with Malfy Italian gin, fresh lime juice,

Since re-opening in July, patrons have been flocking in and for the extended soft opening period reservations were required. 46

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basil, eucalyptus and Fever Tree tonic.

Bites & Bubbles

Beer and wine are also available.

1618 N. Mills Ave., Orlando 32803

Nick is particularly proud of the cheese

407-270-5085 | bitesbubbles.com


lasting impressions IMAGINE SITTING IN A LITTLE BISTRO sipping on a glass of wine and nibbling on charcuterie while stepping into some of the most iconic impressionist masterpieces. The experience, Lasting Impressions, brings brushstrokes by Monet, Renoir, Van Gogh and other impressionist artists to life with one-of-a-kind 3D LED technology in the Alexis & Jim Pugh Theater at the Dr. Phillips Center for the Performing Arts through September 26. You’ll be surrounded by more than 100 classic Impressionist pieces and thanks to Holographic 3D, you can sit with Renoir’s luncheon guests, dance with Degas’ ballerinas, float over Monet’s water lilies, soar into Van Gogh’s starry night, spend Sunday in the park with George, and move among the famous characters on Seurat’s Isle of La Grande Jatte. The colors and textures envelope you as perfectly timed music creates an inspiring ambience — including pieces by Debussy and Ravel, as well as French standards by Piaf, Aznavour and Mouskouri. But in the last song, Vincent by Don McClean, the operatic voice of Adam Fisher is beautifully haunting and brought us to tears as Vincent van Gogh’s landscapes and selfportraits float out from the screen. In an hour you will be fully immersed in sights, sounds and tastes. Lasting Impressions is a one-hour, timed-entry experience that is perfect for all ages and wheelchair-accessible. Showings are available Wednesday — Sunday at 3pm, 5pm and 7pm. Plan to arrive early to enjoy the entire experience as doors open before show time and food and drink is available for purchase. drphillipscenter.org – Christi Ashby september | october 2021

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f

alling FOR

FASHION ORLANDO AREA RETAILERS ARE READY FOR AUTUMN, AND THEY SHARE WHAT’S TRENDING AND IN STORE FOR EVERYTHING FROM FORMAL GALAS TO CASUAL BRUNCHES. ’TIS THE SEASON TO DRESS UP AGAIN IN SHIMMERY, SEQUINED AND EMBROIDERED GOWNS, TAILORED CITY SUITING, FLIRTY, FLOWY DRESSES FOR ALMOST ANY OCCASION, AND EVEN DESIGNER DENIM. CLEAR YOUR CLOSET FOR SOME FABULOUS NEW ARRIVALS FROM MONKEE’S, TUNI, BLOOMINGDALE’S, NEIMAN MARCUS AND SHOPMODA.

This page: BCBG Maxazria halter gown, $448, and Jimmy Choo suede clutch, from Bloomingdale’s Opposite, from left: Jovani royal blue sequined gown, $595, and Auden Harper crystal earrings, $278, from Neiman Marcus Pamella Roland embellished gown, $6,995, and Mignonne Gavigan Madeline beaded statement earrings, $225, from Neiman Marcus 50

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From left: Isabel maxi dress, $239, Hammer metal floral earrings, $65, and Garden Party beaded clutch, $125, from ShopModa Herve Leger fringe dress, $1,590, from Bloomingdale’s; wallet from Tous Ana cinched maxi dress, $249, Sadie clutch, $150, and Rachel headband, $25, from ShopModa 52

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Halston X Netflix Liza gown, $1,295; Jeffrey Campbell Siren booties, $125; Be-Je pearl hoops, $85; and Kelly Cimber bracelets, $80 each; from Tuni

september | october 2021

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Above: Marella Gaudio sweater, $275; Marella Max Mara skirt, $265; Chinese Laundry Ecru boots, $130; Phillip Allen Hefner LV necklace, $318; Taylor & Tessier Fallon bracelet, $275; Tom Ford Anoushka acetate sunglasses, $400; ADA wrap belt, $115; Day and Mood Lee backpack, $288; from Tuni

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Above: Marie Oliver Alice ruffle dress, $438; Brenda Zaro shoes, $168; Ever Alice Maya earrings, $102; Hazen and Enewton bracelets, $38-80; Tiana handbag, $180; from Monkee’s of Winter Park Left: Amethyst Vibes bodysuit, $110; Ruffles midi skirt, $115; Puffy Link Clutch in lime, $125; and Tres Chic leather and ribbon earrings, $75; from ShopModa


Right: Joy Joy skort, $113, and Joy Joy top, $85; Mignonne Lolita hoops, $75; Enewton bracelets, $38-68; Dolce Vita Zina sneakers, $100; from Monkee’s of Winter Park

Below: Crosby Blaire top, $178; AG legging ankle, $188; Sheila Fajl earrings, $98; JSB bracelets, $40 each; Chocolat Blu Web wedge sandals, $165; Hammitt bag, $345; from Monkee’s of Winter Park

Left: AS by DF Mercury recycled leather; $450, Marella Mode top, $345; Marella Lanna pants, $345; Phillip Allen Hefner LV long toggle necklace, $318; Tom Ford Gia acetate sunglasses, $495, Chinese Laundry Ecru boots, $130; Day and Mood Lee backpack, $288; from Tuni

september | october 2021

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where to SHOP

BLOOMINGDALE’S The Mall at Millenia 4152 Conroy Road Orlando 32839 bloomingdales.com

NEIMAN MARCUS The Mall at Millenia 4170 Conroy Road Orlando 32839 neimanmarcus.com

SHOPMODA 1519 Lake Baldwin Lane, Suite B Orlando 32814 shopmodausa.com

MONKEE’S of WINTER PARK 444 W. New England Ave., Suite 115 Winter Park 32789 monkeesofwinterpark.com

THE GROVE 341 N. Pennsylvania Ave. Winter Park 32789 thegrovewp.com Oliphant ruffle collar button maxi dress, $288, from The Grove Blythe top, $60; 7 For All Mankind military ankle skinny jeans, $118; Seba Mid Tote in baby pink, $205; and Goodr Operation Black Out sunglasses, $27; all from The Grove Cover Credits: Ieena for Mac Duggal pleated long sleeve gown, $458, from Bloomingdale’s 56

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TUNI 301 S. Park Ave. Winter Park 32789 shoptuni.com Looks from Bloomingdale’s and Neiman Marcus were photographed in the Personal Stylist Suite at The Mall at Millenia. To learn more about complimentary personal styling sessions, visit mallatmillenia.com/events/ personal-stylist/


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