Lone Star: Winter 2013 MSConnection

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friends, camaraderie with the other participants and research staff, and the development of a support network. Six claimed they had positive emotional responses due to the exercise program that included pride of accomplishment and a better mood. “I smile a lot more and that’s good,” noted one woman.

before it becomes a tool that can benefit treatment decisions made by people with MS and their health care providers.

Testosterone Prevents Nerve Impairments in MS Study

A new $100,000 annual cash prize has been established to recognize scientists whose inventive work is propelling measurable MS research progress. The Barancik Prize for Innovation in MS Research recognizes an exceptional scientist or team whose work in MS research has demonstrated outstanding innovation and originality. The prize is made possible by the generosity of the Charles and Margery Barancik SO Foundation, and is administered through the National Multiple Sclerosis Society. “We are proud to steward the new Barancik Prize, the largest ever established to spur progress toward stopping MS, restoring function and ending MS forever,” said Cyndi Zagieboylo, President and CEO of the National MS Society. “This is the latest in a long history of generous support for MS research provided by Charles and Margery Barancik, and it reflects their wish to speed this vital work.” The first prize will be given in May 2013. Nominations are accepted until Jan. 31, 2013. A selection committee comprised of leaders in science, medicine and MS advocacy will review nominees for their exceptional innovation and originality, impact and potential of the research to lead to pathways for the treatment and cure for MS, and accomplishments that merit recognition as a future leader in MS research.

Researchers funded by the Society have shown that the male sex hormone testosterone prevented or restored impairments in nerve impulse transmission in mice with EAE, an MS-like disease. The improvements specifically occurred in an area of the brain associated with cognitive function, lending evidence to the potential use of sex hormones to treat this MS symptom. This team is currently conducting clinical trials to determine whether estriol (another sex hormone, added on to standard therapies) improves disease activity and cognition in women with MS. Genes May Help Categorize Disease Course and Response to Therapy A team led by Philip L. De Jager, M.D., a Harry Weaver Scholar of the National MS Society from Harvard’s Brigham and Women’s Hospital in Boston, has discovered that differences in active genes – detectable in blood samples – have the potential to be used to group people with MS into categories that predict disease course and response to therapy. Further research is needed to refine this approach

New Innovation Prize Created to Spur Research Progress

For more information on breakthrough research and clinical trials, visit the National MS Society online at nationalMSsociety.org and click on the “Research” tab. Moving Toward A World Free of MS

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