Pathology of Poultry Diseases

Page 3

Cells involved in inflammation 1-Heterophils: have lance-shaped granules, lack myeloperoxidase and alkaline phosphatase, have glucuronidase and acid phosphatase : Very phagocytic Granules tend to round up in tissues, difficult to identify 2-Eosinophils: have spherical granules. Function is not known; but it present in hypersensitivity and associated with eosinophilic enteritis in turkeys due to ascarids. 3-Basophils: contain histamine, involved in acute inflammation. 4-Thrombocytes: small round to oval cells with clear cytoplasm and small round nucleus (looks like small lymphocyte), phagocytic 5-Monocytes: precursors to cells of MPS, phagocytic, can fuse together to form multinucleated giant cells and make monokines; IL-1, IL-2, TNF, G-CSF, gamma interferon. 6-Lymphocytes: various morphologies involved in subacute inflammation including plasma cells.


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