Report IEO 2012

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Disease- Area Surgical Oriented Research

Disease-Oriented Research – Gynecological Tumors

Medical Division of Gynecologic Tumors Nicoletta COLOMBO Director

STAFF Senior Deputy Directors: Gabriella Parma, MD Assistants: Maria Teresa Lapresa, MD, Rosanna Mancari, MD, Annalisa Garbi, MD Research Fellow: Melita Moioli, MD Data Managers: Maira Biggiogero, ScD, Sara Boveri, ScD Secretaries: Gloria Gavioli, Diana Valli Director Fertility and Procreation Unit: Fedro Peccatori, MD, PhD Research Fellow: Maria Anna Sarno Counselor: Leonora Chiavari

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IEO — Scientific Report 2012 — Ongoing Research 2013

Activities 2012.

The Division of Gynecologic Oncology strictly interacts with the Division of Gynecologic Surgery and Gynecologic Prevention to provide diagnosis, treatment and follow-up of women affected by gynecological malignancies. Each staff member is a fully-trained gynecologic oncologist, responsible for various activities within the Division, including the administration of anti cancer agents and supportive care. All staff members are involved in multidisciplinary patient management, shared decision making within dedicated tumor boards, pathology discussion and radiological review of the most significant cases. Patients and their families access to psychological support and decisional counseling, if needed. A specific focus on translational research and clinical trials characterize the research activities of the Division. Clinicians from the Division of Gynecologic Oncology are principal investigators in several international and national trials, addressing new treatment strategies in ovarian cancer, endometrial cancer and cervical cancer. Most of the clinical trial are run in co-operation with MaNGO, Mario Negri Gynecologic Oncology Group, and Gynecologic Cancer Intergroup, an organization of international cooperative groups for clinical trials in gynecologic cancers. A particular attention is devoted to young patients affected by early stage epithelial ovarian cancer, germ cell tumors, endometrial cancer and cervical cancer. For this specific group of patients a dedicated clinical pathway has been identified, with a special emphasis in preserving their fertility. Recently, the Unit of Fertility and Procreation has joined the Division of Gynecologic Oncology. Young patients with gynecological malignancies, breast cancer, malignant lymphomas and other solid tumor have the opportunity to freeze ovarian cortex or oocytes prior to chemotherapy, surgery or radiation therapy. Gamete storage is performed in cooperation with other Istitutions, thus allowing fertility recovery also after gonadotoxic treatments.

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