Nutramedic &Cosmetics
Promising Potential of ® Mobilee in Muscle Health New research indicates that Mobilee® – Bioiberica’s hyaluronic acid matrix ingredient for mobility – supports muscle health and may play a role against sarcopenia – a progressive musculoskeletal disorder characterised by loss of muscle strength, mass and function.
T
he results, which were presented at the world’s leading clinical conference for bone, joint and muscle health, WCO-IOF-ESCEO (4-7 May, Bar celona), highlight the exciting potential of Mobilee® in nutritional solutions targeted towards muscle health, and overall mobility. The aim of the present research was to evaluate the effect of Mobilee® on muscle health specifically, using in vitro models of health and sarcopenia. Myo cytes (muscle cells) were treated with 6 µg/mL di gested Mobilee® for 24 hours. Effect in muscle ho meostasis (measured by assessing the proliferation and hyperplasia of myocytes) and protection against muscle damage and atrophy were evaluated. The re sults showed that Mobilee® promoted myocyte hy perplasia (increase in myocyte size) by 7% and myo cyte proliferation (production of new cells) by more than 20%. The ingredient also showed an effect against muscle atrophy, muscle damage and cell death in the sarcopenia model. “We are one of the first organisations to explore the role of hyaluronic acid-rich solutions on muscle health,” says Daniel Martinez-Puig, Head of R&D Hu man Health, Bioiberica. “Mobilee® is the result of 15plus years of research and development and is back ed by robust scientific research demonstrating its unique benefits in joint and muscle health. This lat est evidence points towards its potential to play a supportive role in muscles too; where it may be ef fective for balancing muscle cell turnover and protect
16
ing against common characteristics of sarcopenia.” Jaume Reguant, Healthcare Director, Bioiberica adds: “Western societies are ageing and there is a progres sive rise in the prevalence of muscle disorders, like sarcopenia – which significantly impact an individu al’s overall mobility, independence and quality of life. Simultaneously, there is a greater focus on exercise and remaining active, both in younger, healthier po pulations and older generations. Consumers recog nise that good mobility goes beyond looking after joint health alone and they understand that nutritio nal support can aid their mobility. With this in mind, it’s an exciting time to innovate with a premium, ea sy-to-formulate ingredient, like Mobilee®. It taps into multiple market trends and consumer preferences – from the active nutrition movement to rising demand for multi-ingredient solutions that bring holistic health benefits, as well as increasing appetite for conveni ent, low dose and science-backed products.” Mobilee® is the first hyaluronic acid matrix ingre dient available for innovation in the mobility market; demonstrated to support joint and muscle health at a low dose of only 80 mg/day. A patented ingredient made up of three naturally-occurring components – hyaluronic acid (60-75%), polysaccharides and colla gen – Mobilee® is powering new advancements in the joint and muscle health and mobility categories. It is suitable for dietary supplement and functional food applications. www.bioiberica.com
