Gene Therapy & Molecular Biology Volume 10 Issue B

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Günzburg et al: New generations of retroviral vector for safe, efficient and targeted gene therapy Structural and functional analysis of the RNA transport element , a member of an extensive family present in the mouse genome. J Virol 79, 2356-2365. Tabotta W, Klein D, Hohenadl C, Salmons B and Gunzburg WH (2001) Tightly controlled expression of transduced genes by reconstituting retroviral vectors. J Gene Medicine 3, 418-26. Vivinus S, Baulande S, van Zanten M, Campbell F, Topley P, Ellis JH, Dessen P, Coste H (2001) An element within the 5’ untranslated region of human Hsp70 mRNA which acts as a general enhancer of mRNA translation. Eur J Biochem 268, 1908-1917. Weber E, Anderson WF and Kasahara N (2001) Recent advances in retrovirus vector-mediated gene therapy: teaching an old vector new tricks. Curr Opin Mol Ther 3, 439-53. Zhang Y, Rassa JC, deObaldia ME, Albritton LM and Ross SR (2003) Identification of the receptor binding domain of the mouse mammary tumor virus envelope protein. J Virol 77, 10468-78. Zhao Y, Low W and Collins MKL (2000) Improved safety and titre of murine leukaemia virus (MLV)-based retroviral vectors. Gene Ther 7, 300-305. Zhu Q and Dudley JP (2001) A retroviral model for tissuespecific transcription: lessons for gene therapy. Gene Ther Mol Biol 6, 169-181.

Zufferey R, Donello JE, Trono D and Hope TJ (1999) Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors. J Virol 73, 2886-92.

Walter H. Günzburg

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