WHY MLS Laser Therapy

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PITCHING QUALITY


WHAT DO YOU OFFER WHEN YOU SEE THESE CASES?


WE HAVE THE ANSWER, MLS速 LASER THERAPY. EFFECTIVE NO INVASIVE FAST & LONG LASTING RESULTS


WHAT IS IT?

WHY IS IT EFFECTIVE?

WHICH ARE THE RESULTS?

WHY INCORPORATING IT IN YOUR CLINIC?


What is MLS® Laser Therapy?

MLS® Laser Therapy is an innovative technique, revolutionizing the therapeutic approach of musculo-skeletal and dermatology problems in Veterinary, and it’s the result of a long path of scientific research and technological innovation.


What is MLS® Laser Therapy?

 2 SPECIFIC WAVELENGTHS: 808 & 905 nm

 TARGET AREA  2 PRODUCT FAMILIES

 2 EMISSION MODALITIES: CONTINUOS & PULSED

 2 ADDITIONAL INTERCHANGEABLE HEADS

 COMBINATION AND SYNCHRONIZATION

 APPLICATIONS MODALITIES

 SPATIAL OVERLAPPING

 SPECIFIC PROTOCOLS


What is MLS® Laser Therapy? 2 SPECIFIC WAVELENGTHS  OPTIMAL PENETRATION MLS® Laser Therapy is based on two laser sources with 2 different wavelengths:

 The chosen wavelengths represent the most studied ones and guarantee that energy is taken to the deepest possible level

Absorption coefficient

 808 and 905 nm


What is MLS® Laser Therapy? 2 EMISSION MODALITIES (CONTINUOS & PULSED)  ADVANTAGES OF BOTH HP & LLLT The MLS® (Multiwave Locked System) impulse is based on 2 different emissions granting different biological effects:  A pulsed emission (905 nm) with the same power as Low Level Laser Therapy  A continuous/chopped emission (808nm) with the typical characteristics of High Power.

808nm CW 905nm PW f=2000Hz

808nm FW 905nm PW f=1-2000Hz


What is MLS® Laser Therapy? COMBINATION & SYNCRONIZATION  SINERGY OF THERAPEUTIC EFFECTS The combination and synchronization in one single pulse of specific continuous and pulsed emissions, produces the synergy and strengthening of the single effects: analgesic, anti-inflammatory, anti-edema.

SPATIAL OVERLAPPING  HOMOGENEOUS ENERGY DISTRIBUTION Two laser sources form a spatial overlap over most of the length, distributing the energy on the treatment area in homogeneous way.


What is MLS® Laser Therapy? TARGET AREA  INTRO-ARTICULAR + MUSCLE STIMULATION The emitted energy is directed through an optical group over a large Target Area, so a large volume below the skin with two different applicators:  Handpiece (3cm2)  optical windows & trigger points

 Multidiode applicator (20 cm2)  Big areas & muscular stimulations


What is MLS速 Laser Therapy? 2 DIFFERENT PRODUCT FAMILIES


What is MLS® Laser Therapy? 2 INTERCHANGEABLE HEADS  INTRAORAL + LASER PUNCTURE (Vet Orange only)


What is MLS® Laser Therapy? APPLICATIONS MODALITIES  POINT BY POINT & SCANNING

POINT BY POINT This technique allows to easily treat small and irregular areas (ex. joints)

SCANNING This technique may be used over smooth areas (muscles, paraspinal areas) or on extensive wounds


What is MLS® Laser Therapy? SPECIFIC PROTOCOLS  FOR CATS, DOGS, EQUINE & EXOTICS Mphi Vet is equipped with software with special protocols for cats, dogs, equine and exotic animals*. The desired species can be selected from the main menu and then the user is guided to most suitable protocol.

*only Vet Orange


What is MLS速 Laser Therapy?

MLS速 Laser Therapy born from ASAlaser experience: historical scientific tradition, leader position in the market. ASAlaser has more than 30 years history completely focus on laser therapy, driving this market from the beginning.


What is MLS® Laser Therapy? After a long experience in manufacturing different type of lasers for Surgery and Physical Therapy, e.g..: • Low Level Laser (LLLT, class 3B): Diode •

High Power Laser (HP, Class 4): - CO2 25W, - Semiconductor Diode 6W, - Argon 10 W

ASA, looking to the future, has begun a new line of research, that has led to the identification of a new patented pulse, giving rise to the new therapy


What is MLS® Laser Therapy? MLS® Laser Therapy, the same technology used in human field, is the last result of our long scientific tradition.

FROM HUMAN MEDICINE..

…TO VETERINARY MEDICINE


What is MLS速 Laser Therapy?

MLS速 Laser Therapy is not just the result of a simple assembling of different laser sources, but the real therapeutic solution coming from a long scientific pathway, moving from POWER to DISCIPLINE.


WHAT IS IT?

WHY IS IT EFFECTIVE?

WHICH ARE THE RESULTS?

WHY INCORPORATING IT IN YOUR CLINIC?


Why is it effective? SCIENTIFIC EVIDENCES… BEYOND THE ATP

 The MLS® impulse modulates cellular metabolism and improves the supply of energy  The increase of PP1 (Protein phosphatase 1) created by the therapeutic process, regulates the muscle relaxation / contraction process  It stimulates also the accumulation of glycogen supplies (energy source needed for muscular activity)


Why is it effective? SCIENTIFIC EVIDENCES… BEYOND THE ATP

 The thermal effects of MLS® Laser Therapy generate indirect photomechanical effects  They mechanically stress the cells. This kind of stress favors tropism, homeostasis and cell differentiation  It favors the recovery of damaged tissue  The MLS® impulse produces measured thermal effects and always remains under the danger threshold  It stimulates biochemical reactions and vasodilatation  It increases the ratio of oxygen and nutrients in the treated area  Moderate vasodilatation favors inflammatory process recovery and oedema reabsorption


Why is it effective? SCIENTIFIC EVIDENCES… BEYOND THE ATP  Proteomic studies conducted on muscle cells (myoblasts) have shown that MLS® treatment induces an increase of anti-inflammatory protein NLRP 10  NLPR 10 inhibits the production of pro-inflammatory interleukins IL-1β and IL-18, reducing inflammation  The decrease of inflammation leads to a normalization of vascular function and thus a decrease of edema  The reduction of inflammatory mediators and edema implies a reduction of pain symptoms


Why is it effective? SCIENTIFIC EVIDENCES… BEYOND THE ATP

The MLS® impulse grants proved analgesic effect

Effect of MLS treatment on hyperalgesia induced by CCI

PAW PRESSURE (G)

8 6 CONTRA 4

IPSI

2

IPSI + I MLS appl

0 Rat 1

Rat 2

Rat 3

Rat 4


WHAT IS IT?

WHY IS IT EFFECTIVE?

WHICH ARE THE RESULTS?

WHY INCORPORATING IT IN YOUR CLINIC?


Why incorporating it in your clinic? MLS® Laser Therapy is indicated for the treatment of several conditions in small animals (pets and exotic), and equine related to locomotor apparatus and dermatology.

JOINTS: trauma, DJD, osteoarthritis

MUSCLES: sprain, strain, trigger points and stress point therapy, injuries, muscle contractures

TENDONS & LIGAMENTS: tendonitis, desmitis, partial ruptures


Why incorporating it in your clinic?

IVDD and spinal pathologies

BONE HEALING post surgery or post fracture

PAIN MANAGEMENT post surgery

PAIN acute or chronic


Why incorporating it in your clinic?

 OEDEMA

 SKIN WOUNDS


Why incorporating it in your clinic?

 LICK GRANULOMAS  BURNS  HOT SPOTS  ANAL GLANDS IMPACTION


Why incorporating it in your clinic?

 DERMATITIS, PYODERMITIS

 STOMATITIS


Why incorporating it in your clinic? ADVANTAGES FOR VETERINARY

New therapeutic treatment for pain management, inflammation, pathologies of osteo-muscular apparatus and skin diseases

No invasive, no side effects

Combination between therapy and diagnostic as alternative / combined solution of pharmacology treatment

Scientific innovation that increases the value of the clinical center and the number of patients, and therefore, the economic return


Why incorporating it in your clinic? ADVANTAGES FOR VETERINARY

Loyalty of customers and greater prestige/professionalism for the hospital/clinic

Deliver best patient outcomes: precision in diagnosis and treatment removes the guesswork

Economical Return: considering that MLS® Laser Therapy will become a routine practice before or after the received service, and the growing number of patients thanks to the new offered treatments


Why incorporating it in your clinic? ADVANTAGES FOR VETERINARY 

Standard of care: Incorporating MLS® Laser Therapy is a “must have” technology in a VET practice. It will be the “standard of treatment”

Lead the way: start to use state of the art technology that puts you at the forefront of your profession

As number of users grows: in all the markets, it becomes not an optional offer used only by elite practices, but an indispensable treatment tool

Competitive landscape: as soon as you will start offering the MLS®, your competitors will be under pressure to keep pace and get the technology as well


Why incorporating it in your clinic? ADVANTAGES FOR PATIENTS AND OWNERS

Faster return to normal conditions and therefore to life with the owner or agonistic activity

Improved quality of life for animals and their owners

Reduction or exclusion drug use (vs pharmacologic treatments)

Not trying to doping


Why incorporating it in your clinic?

http://www.asaveterinary.com/en/roi-calculator


WHAT IS IT?

WHY IS IT EFFECTIVE?

WHICH ARE THE RESULTS?

WHY INCORPORATING IT IN YOUR CLINIC?


Which are the results? MLS速 EFFECTIVE IN DEPTH

Elephant Sanctuary - Tennessee


Which are the results? MLS速 EFFECTIVE IN DEPTH

Kansas City Zoo


Which are the results? MLS速 EFFECTIVE IN DIFFICULT CONDITIONS

Gulf World Marina Park - Florida


Which are the results? CLINICAL CASES SELECTION

Jacinto, White Swiss Shepherd Dog with left elbow fracture Courtesy of Dr. テ]gela Romano - "Laser Pets" - Bogotテ。, Colombia Species: dog Breed: White Swiss Shepherd Dog Gender: male Age: 1 YO Name: Jacinto Clinical case: Jacinto had a Salter-Harris fracture to the left elbow. He had orthopaedic surgery and a screw was used to reduce the fracture. The fracture did not heal and Jacinto had lameness, edema and muscular hypotrophy. X-ray shows arthrosis and sclerosis of the radius proximal line of growth. A multivitamin, mineral and joint supplement has been recommended. Therapy: As two months later the fracture did not heal, Jacinto began MLS ツョ Laser Therapy sessions. The whole left forelimb was treated, especially the elbow joint. For the first two sessions has been used the Edema program. Later were used Pain (chronic) and Inflammation (chronic) programs twice a week. Jacinto had 8 more applications two times a week, alternating Inflammation (acute), 18 Hz and, Sprain/Strain, 1168 Hz, programs in each session.


Which are the results? CLINICAL CASES SELECTION Zeppelin, Jack Russell Terrier with bite injuries Courtesy of Anita Jansen, Physiotherapist for dogs - “Hund i Form” - Sola (Rogaland), Norway Species: Dog Breed: Jack Russel Terrier Gender: Male Age: 7 YO Name: Zeppelin Clinical case: During a walk, Zeppelin was attacked by a big size dog and was bitten in the neck, abdomen and left hind leg. He had three injuries to the abdomen, one was very close to the urethra, and two in the neck and lumbar area. Zeppelin had surgery in the night to suture abdominal wounds. He was sutured in the neck and lower back region, too. Two days after the attack, began to appear the first bruises on Zeppelin’s abdomen. Because of the very strong inflammation and infection, the value of the CRP exceeded 250 (normally is less than 35). Therapy: In addition to surgery, Zeppelin received immediately after the attack antibiotics and anti-inflammatory drugs. Two days after surgery he had the first sessions MLS® Laser Therapy. The protocols adopted were “infected wound" and then "wound." Zeppelin had 4 sessions of MLS® Laser Therapy: the first two every three days, the others once a week until complete healing, which occurred 3 weeks after surgery. 36 hours after the first treatment, bruises begin to decrease and the fever disappears After the second session of MLS® Laser Therapy: the wounds are completely closed. 3 weeks after surgery, bruises have disappeared, and he is beginning again to extend the hind legs when resting. Zeppelin participated in Rally-Obedience competition 6 weeks after the attack, and won Class 3!


Which are the results? CLINICAL CASES SELECTION Polyarthritis in a Highland fold Courtesy of Dr. Roberta Burdisso, Physiotherapy Service Director at CHV Fregis - Paris, France

Species: Cat Breed: Highland fold Gender: Male Age: 4 YO

Clinical case: Highland fold is a feline breed with genetic predisposition to develop osteochondrodysplasia. Harold was visited for gait problems. He was feeling severe pain in multiple joints (carpus, tarsus, knee) and in the cervicothoracic spine tract too. Therapy: The first three weeks Harold had 6 sessions of MLS速 Laser Therapy: three sessions on the first week, two sessions on the second and the last one on the third week. The maintenance program is going to be continued with two treatments per month. The programs used were "back pain" for the column and "chronic arthritis" for the joints. Today Harold walks normally and has 2 sessions per month as a maintenance program.


Which are the results? CLINICAL CASES SELECTION Skin lesion on a fancy hairless rat Courtesy of Dr. Giordano Nardini, Clinica Veterinaria Modena Sud - Modena, Italy

Species: fancy hairless rat Gender: Male Age: 1 ½ YO Name: Jerry

Clinical case: This fancy hairless rat has been presented at first visit showing a crusty and ulcerated skin lesion on the neck. The lesion was one week old, progressively worsening. Therapy: Antibiotic therapy has been administered (Baytril) and an MLS® Laser Therapy treatment cycle started. MLS® Laser Therapy has been applied every other day using the pre-set program “Infected wound” for 4 sessions, then switching to the pre-set program “Wound” starting from the 5th session, for a total number of 10 applications. Mphi Vet device has been applied using the “point to point” modality and the lesion has been treated applying the handpiece on two points, for a total treatment time of 12 seconds per session. Along treatment the lesion quickly and progressively improved, and was looking almost completely healed at the end of the cycle.


Which are the results? CLINICAL CASES SELECTION Tendon tear in a saddle horse Courtesy of Dr. Tatjana Falconi, DVM hippiatrics - Brescia, Italy

Species: Horse Breed: Sella italiano Gender: Gelding Name: Vaucluse

Clinical case: A month and a half before the first visit, Vaucluse suffered a severe tear of carpal retinaculum of its left front limb. At the first visit, 6 weeks after the injury happened, the horse showed lameness (4/5), with oedema and pain at the metacarpal region. Therapy: MLS速 Laser Therapy applied 3 times/week for 3 consecutive weeks. The first application of MLS速 Laser Therapy brought an obvious reduction of the oedema.


TESTIMONIALS


Which are the results? TESTIMONIALS

https://www.facebook.com/wyominganimalhospital


Which are the results? TESTIMONIALS

https://www.facebook.com/pages/Cranbrook-Veterinary-Centre/116156501924101


Which are the results? TESTIMONIALS

https://www.facebook.com/TVARF?fref=nf


Which are the results? TESTIMONIALS

https://www.facebook.com/dittdyrshelseas


Which are the results? TESTIMONIALS

https://www.youtube.com/user/DrJyl/videos

https://www.facebook.com/pages /VARK/315934611068


Which are the results? TESTIMONIALS

https://www.facebook.com/PolsloeVeterinaryClinic


Which are the results? TESTIMONIALS

https://www.facebook.com/StonebridgeAnimalHospital


Which are the results? TESTIMONIALS

https://www.facebook.com/wyalusingpetclinic


Which are the results? TESTIMONIALS

https://www.facebook.com/stbernards


Which are the results? TESTIMONIALS

https://www.facebook.com/WOVH.NC


Which are the results? TESTIMONIALS

https://www.facebook.com/munfordanimal


HOW WE CAN HELP YOU


Training  ON LINE - Platform  ON SITE


Marketing Tools WEB  Internet Website www.asaveterinary.com  Newsletters


Marketing Tools WEB  Interviews & Clinical cases


Marketing Tools ASAVETERINARY APP (TABLET)

30 tutorials that show MLS速 correct functioning concerning single body regions; a selection of documented medical cases; special contents dedicated to single illnesses pertaining to different animal species.


Marketing Tools Poster

Roll up


Marketing Tools Flyer Pets


Scientific publication ENERGY FOR HEALTH

The results of the work of medics and specialists who collaborate with ASA, that illustrate the actions principles of MLS速 Laser Therapy and the scientific evidence that brought to their clinical validation.


MLS® Laser Therapy - Bibliography IACOPETTI I, PERAZZI A, MANIERO V, MARTINELLO T, PATRUNO M, GLAZAR M, BUSETTO R. (2015) Effect of MLS® Laser Therapy with Different Dose Regimes for the Treatment of Experimentally Induced Tendinopathy in Sheep: Pilot Study Photomedicine and Laser Surgery; 33(3): 154-163. doi:10.1089/pho.2014.3775.

BENNETT C A, OLMOS S R (2014) Treatment of Chronic Craniofacial Pain with Mphi Laser and Orthotic ENERGY FOR HEALTH; 13:4-8 VILIANI T (2014) Laserpuncture with MLS® (Multiwave Locked System) system Mphi: safety and clinical efficacy in joint disease, preliminary data. ENERGY FOR HEALTH; 13:14-18 ROSSI F, PINI R, ROMANO G, CIALDAI F, FUSI F, MONICI M (2014) A predictive analysis of thermal effects in pigmented skin and underlying tissues during IR laser therapy ENERGY FOR HEALTH; 12:4-10

PASTERNAK K, NOWACKA O, WRÓBEL D, PIESZYŃSKI I, BRYSZEWSKA M, KUJAWA J (2014) Influence of MLS laser radiation on erythrocyte membrane fluidity and secondary structure of human serum albumin Mol Cell Biochem; 388:261–267 KURYLISZYN-MOSKAL A, KITA J, DAKOWICZ A, CHWIEŚKO-MINAROWSKA S, MOSKAL D, KOSZTYŁA-HOJNA B, JABŁOŃSKA E, KLIMIUK PA (2014) The influence of Multiwave Locked System (MLS) laser therapy on clinical features, microcirculatory abnormalities and selected modulators of angiogenesis in patients with Raynaud’s phenomenon. Clin Rheumatol; DOI 10.1007/s10067-014-2637-8


MLS® Laser Therapy - Bibliography MOMANU A (2013) Comparison of analgesic and anti-inflammatory effects of the classical low level laser therapy and multiwave locked system in inflammations of serous bursae. Sports Medicine Journal / Medicina Sportiva; 9 (4):2234-2240 MONICI M, CIALDAI F, RANALDI F, PAOLI P, BOSCARO F, MONETI G. CASELLI A (2013) Effect of IR laser on myoblasts: a proteomic study. Molecular Biosystems; 9 (6):1147-61 GALANTI G, STEFANI L, IACCHI A, LONERO L, MORETTI A (2013) The effect of MLS laser therapy in élite football players affected by muscles injuries: a controlled clinical trial. ENERGY FOR HEALTH; 10:4-8 PASTERNAK K, WRÓBEL D, GWORYS K, KUJAWA J (2012) Wpływ promieniowania laserowego mls na aktywności atpazowe błon erytrocytów ludzkich (Effect of MLS laser radiation on the atpase activity of human erythrocyte membranes) Kwart. Ortop. 1, str. 74, ISSN 2083- 8697 KĘDZIERSKI T, STAŃCZAK K, GWORYS K, GASZTYCH J, SIBIŃSKI M, KUJAWA J (2012) Comparative Evaluation of the Direct Analgesic Efficacy of Selected Physiotherapeutic Methods in Subjects with Knee Osteoarthritis. Preliminary Report Ortop Traumatol Rehabil.;14 (6):537-44 GWORYS K, GASZTYCH J, PUZDER A, GWORYS P, KUJAWA J (2012) Influence of Various Laser Therapy Methods on Knee Joint Pain and Function in Patients with Knee Osteoarthritis Ortop Traumatol Rehabil.;14 (3): 269-77.


MLS® Laser Therapy - Bibliography RIOJA TORO J, ESTÉVEZ POY PJ, MARTÍNEZ PARDO F (2012) Estudio prospectivo, aleatorizado y controlado con placebo, para valorar la eficacia del tratamiento con láser, asociado o no aortesis de muneca en el síndrome del túnel del carpo idiopático. (A prospective, randomized and placebo controlled study of the efficacy of treatment with laser, with or without splinting of wrist in idiopathic carpal tunnel syndrome) Rehabilitación (Madr); 46(2):92--102

MONICI M, CIALDAI F, ROMANO G, CORSETTO PA, RIZZO AM, CASELLI A, RANALDI F (2012) Effect of IR Laser on Myoblasts: Prospects of Application for Counteracting Microgravity-Induced Muscle Atrophy. MICROGRAVITY SCIENCE AND TECHNOLOGY; 25(1):35-42 RADER A (2012) The affect of MLS therapy on nerve conduction parameters in developing diabetic sensory peripheral neuropathy. ENERGY FOR HEALTH; 9:4-7 NUNEZ G, BERTOLINI D, PISCOPO C (2012) The MLS® therapy in postural myofascial pain and postraumatical of the neck. ENERGY FOR HEALTH; 9:8-11 GALANTI G, MORETTI A, LO NERO L (2012) Application of MLS® laser on muscular contracture caused by functional overload in a young athlete - case report. ENERGY FOR HEALTH; 9:12-14 CARUSO G, GERVASI S, SALVADORI D (2012) Physical treatment of post traumatic gonalgia by NIR laser therapy: a case report. ENERGY FOR HEALTH; 9:15-17


MLS® Laser Therapy - Bibliography RAYEGANI SM, BAHRAMI MH, SAMADI B, SEDIGHPOUR L, MOKHTARIRAD MR, ELIASPOOR D (2011) Comparison of the effects of low energy laser and ultrasound in treatment of shoulder myofascial pain syndrome: a randomized single blinded clinical trial. EUR J PHYS REHABIL MED; 47:391-90 CSAPO A (2011) Efficiency of MLS® therapy in abarticular rheumatism revealed by digital thermography and visual analog scale. ENERGY FOR HEALTH; 8:12-16 KHAMSEH M E, KAZEMIKHO N, AGHILI R, FOROUGH B, LAJEVARDI M, DABAGHIAN F H, GOUSHEGIR A, MALEK M (2011) Diabetic distal symmetric polyneuropathy: Effect of low-intensity laser therapy . LASERS IN MEDICAL SCIENCE; 26 (6): 831-835 DRAGONE L, PALLADINI S, GLAZAR M (2011) MLS® laser Therapy in dogs with pressure ulcers and open wound: case reports. ENERGY FOR HEALTH; 7:20-24 VIGNALI L, CIALDAI F, MONICI M (2011) Effects of MLS® laser on myoblast cell line C2C12. ENERGY FOR HEALTH; 7:12-18 SMIDERLE C, SCAPIN M (2007) MLS® therapy treatment of acute shoulder pain in inflammatory processes of the rotator cuff. ENERGY FOR HEALTH; 1:12-15 CORTI L, ROSA E, NORBIATO V, PEDRINI L (2007) Clinical results in the treatment of ankle and knee distortion pathologies with MLS® therapy. ENERGY FOR HEALTH; 1:30-34


MLS速 Laser Therapy - Bibliography MOGNATO M, SQUIZZATO F, FACCHIN F, ZAGHETTO L, CORTI L (2004) Cell growth modulation of human cells irradiated in vitro with low-level laser therapy. PHOTOMEDICINE AND LASER SURGERY; 4(6): 523-526 CORTI L (2004) MLS速 laser therapy treatment of shoulder pain: a controlled comparative study. SCIENTIFIC REPORT MLS

TASCA A (2004) MLS速 therapy treatment of various osteo/muscolar/tendinous pathologies. SCIENTIFIC REPORT MLS VENTURIN A, ORTOLANI M (2004) Treating chronic lumbago with MLS therapy. A controlled trial. SCIENTIFIC REPORT MLS CORTI L, MACCARI M, ROSA E (2004) Laser Treatment of Cervical Distortion. SCIENTIFIC REPORT MLS GIGO BENATO D, GEUNA S, DE CASTRO RODRIGUES A, TOS P, FORNARO M, BOUX E, BATTISTON B, GIACOBINIROBECCHI MG (2004) Low-power laser biostimulation enhances nerve repair after end-to-side neurorrhaphy: a double-blind randomized study in the rat median nerve model. LASERS IN MEDICAL SCIENCE; 19: 57-65.


Many thanks for your time and interest‌ ‌your considerations and comments will be very welcome: asavet@asalaser.com


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