o f t i t l e s , v i s i t u s a t w w w. c r c p r e s s . c o m Combination Products
Smita Gopalaswamy
Advanced Solutions Consultants, Inc., Parkland, Florida, USA
Dictionary of Marine Natural Products with CD-ROM Edited by
Venky Gopalaswamy
John W. Blunt and Murray H.G. Munro
The field of combination product development is so new that very few publications, including FDA documents, are available. This text provides an overview of the process from start to finish, complete with relevant definitions, and then shows how to establish a design and development plan. It provides an overview of FDA and other regulatory expectations and covers resource requirements, manufacturing, pitfalls, post-launch compliance requirements, and agency audits and challenges. The book presents practical guidelines on how to develop combination products successfully and how to implement them into the market successfully and in a timely manner.
Focusing for the first time on more than 25,000 marine-specific natural products, Dictionary of Marine Natural Products with CD-ROM indexes each product by chemical name, organism type, and compound type. Following a similar format to the Chapman & Hall Chemical Database, this comprehensive volume is mirrored on an accompanying CD-ROM that is fully text and structuresearchable. Each entry includes biological source, chemical structure, physical properties, biological activity, and literature references. This tool offers information essential to the development of novel pharmaceuticals, pesticides, and marine anti-fouling agents derived from unique molecular structures of marine natural products.
Catalog no. 64460, ISBN: 978-1-4200-6446-9 2008, 6-1/8 x 9-1/4, 264 pp. Suggested Price: $139.95 / £77.99
Catalog no. 8216, ISBN: 978-0-8493-8216-1 2008, 8-1/2 x 11, 2536 pp. Suggested Price: $599.00 / £333.00
Johnson and Johnson, New Brunswick, New Jersey, USA
Design and Use of Relational Databases in Chemistry TJ O’Donnell
President, gNova Inc., San Diego, California, USA
University of Canterbury, Christchurch, New Zealand
Functional Protein Microarrays in Drug Discovery
Drug Discovery & Development
Regulatory Challenges and Successful Product Development
99
Edited by
Paul F. Predki
Invitrogen, Branford, Connecticut, USA Series: Drug Discovery Series, 8
Through many examples of good database design, this book shows that relational databases are the best way to store, search, and operate on chemical information. Introducing the concepts of RDMS and SQL, the author describes how relational data tables and new data types help store and use chemical information, how molecular structures can become a new data type in a database, and how client programs can effectively use relational databases. He also explains how a fully functioning chemical relational database system can be built. A supplementary website offers an implementation of every function from the book, a database of structures and data, and examples used in the book.
An ideal text for biotechnologists, protein chemists, and biochemists, Functional Protein Microarrays in Drug Discovery explores all aspects of functional protein microarrays, including basic principles, methods, and applications. The book discusses the generation of functional protein content and describes both standard and state-of-the-art fabrication methods. It reviews current and next generation approaches to assay detection and presents a wide range of applications, from biomolecular interaction discovery and characterization to immune response profiling. The book also addresses several fundamental computational issues, bioinformatics and data analysis.
Catalog no. 64428, ISBN: 978-1-4200-6442-1 January 2009, 6-1/8 x 9-1/4, 224 pp. Suggested Price: $129.95 / £72.99
Catalog no. 9809, ISBN: 978-0-8493-9809-4 2007, 6-1/8 x 9-1/4, 480 pp. Suggested Price: $175.95 / £98.00
Rest of the World Tel: +44 (0) 1235 400 524 • Fax: +44 (0) 1235 400 525 e-mail: (UK) uk.trade@tandf.co.uk • (International) international@tandf.co.uk
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