A traditional alternative, CBD (cannabidiol)

AN ACHIEVEMENT IN THE SCIENCE OF NUTRITION

REGENERATIVE MEDICINE AND LONGEVITY A traditional alternative CBD (cannabidiol)

CBD is a molecule, not a miracle. Many people could benefit significantly from legal access to a wide range of hemp remedies

LIPOSOMAL NANOTECHNOLOGY

Las Vegas, Nevada 2019

HOW DOES CBD WORK?

A small mention What is CBDsomal and what is the CBD? CBDsomal, is a concept focused on the optimal delivery of CBD (cannabidiol), it is a promising element for health that is extracted from hemp (cannabis) without the psychoactive element of THC, it does not get you "High".

Cannabidiol (CBD) is a natural compound found in the resinous flower of cannabis, a plant with a rich history as a medicine that goes back thousands of years. Currently, scientists and doctors around the world are testing and confirming the therapeutic properties of CBD. A safe and non-addictive substance, CBD is one of more than a hundred "phytocannabinoids", which are exclusive to cannabis and give the plant its robust therapeutic profile.

CBD and THC interact with our bodies in different ways. One of the main ways in which they impact us is by imitating and increasing the effects of the compounds in our bodies called "endogenous cannabinoids", so called because of their similarity to the compounds found in the cannabis plant.

These "endocannabinoids" are part of a regulatory system called the "endocannabinoid system" The discovery of the endocannabinoid system has significantly improved our understanding of health and disease.

It has important implications for almost all areas of medical science and helps explain how and why CBD and THC are such versatile compounds, and why cannabis is a plant that greatly alters mood, despite its regulated status The endocannabinoid system plays a crucial role in the regulation of a wide range of physiological processes that affect our daily experience: our mood, our energy level, our intestinal strength, immunological activity, blood pressure, bone density, glucose metabolism , how we experience pain, stress, hunger and more. Â

The fact that CBD is therapeutically potent and not intoxicating, as well as to take as a CBD oil, makes it an attractive treatment option for those who are cautious when trying cannabis for the first time. Â *These statements have not been evaluated by the U.S. Food and Drug Administration. These products are not intended to

diagnose, treat, cure or prevent any disease. Take all supplements as suggested or as directed by your health care professional.

CBD: THE MULTIPURPOSE MOLECULE • Neuropsychiatric disease (autism, ADHD, post-traumatic stress disorder, alcoholism) • Neurological conditions (Alzheimer's, dementia, Parkinson's, multiple sclerosis, epilepsy, Huntington's chorea, stroke, traumatic brain injury) • Gut disorders (colitis, Crohn's disease) • Cardiovascular dysfunction (atherosclerosis, arrhythmia)

Many people are looking for alternatives to pharmaceutical products wich can have severe side effects: a medicine that is more in tune with natural processes. By taking advantage of how we function biologically at a deep level, CBD can provide relief for chronic pain, anxiety, inflammation, depression and many other conditions.

Extensive scientific research, largely sponsored by the US government. And the growing anecdotal accounts of patients and physicians highlight the potential of CBD as a treatment for a wide range of diseases, including (but not limited to): • Autoimmune diseases (inflammation, rheumatoid arthritis) • Metabolic syndrome (diabetes, obesity) • Skin disease (acne, dermatitis, psoriasis).

Both CBD and THC have significant therapeutic attributes. But unlike THC, CBD does not make a person feel "drugged" or intoxicated. This is because CBD and THC act in different ways in different receptors in the brain and body.

CBD has demonstrated neuroprotective effects and its anti-cancer properties are being investigated in several academic research centers in the United States and elsewhere. A brain cancer study conducted in 2010 by scientists in California found that CBD "increases the inhibitory effects of THC on the proliferation and survival of human glioblastoma cells." This means that CBD makes THC even more potent as an anti-cancer substance.

Also in 2010, German researchers reported that CBD stimulates neurogenesis, the growth of new brain cells, in adult mammals.

*These statements have not been evaluated by the U.S. Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Take all supplements as suggested or as directed by your health care professional.

More about liposomes as a delivery system

There has been no greater achievement in nutritional science than the successful application of liposomal technology to the efficient delivery of cellular nutrients.

This simple to understand yet difficult to accomplish advancement has changed the way nutrition can be used to positively influence the biological functions of the human body.

The health-enhancing benefits of consumed nutrients can only be realized if those nutrients are efficiently absorbed at the cellular level. Cellular absorption of consumed nutrients is far more efficient when those nutrients are transported by phospholipid “vehicles” called liposomes.

Advanced liposomal technology is the “heart and soul” of all LifeOsome™ brand nutritional supplements.

Liposomes are microscopic spheres that have a natural affinity for living cells because their outer layers are composed of phospholipids that are virtually identical to the phospholipid composition of cell membranes.

Nutrients that are carried by nano-sized liposomal “delivery vehicles” are very efficiently absorbed because they are naturally “welcomed in” by the cells they are being delivered to. It is this safe, efficient access to the interior of a living cell that affords the opportunity for unprecedented advancements in the field of human nutrition.

LifeOsome™ liposomes can range from 100nm to 450nm in diameter

*These statements have not been evaluated by the U.S. Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Take all supplements as suggested or as directed by your health care professional.

Scientists sometimes refer to liposomal agents as nanoliposomals because they are so small that they must be measured in nanometers. A nanometer (nm) is a unit of measurement that is equal to one millionth of a millimeter.

Discovered in 1961 by Dr. Alec Bangham, a British hematologist who was studying phospholipids at the Babraham Institute in Cambridge, liposomes have paved the way for many advancements in biochemistry and medicine. Utilizing liposomes for cellular delivery of nutrients, however, is a relatively recent development.

Bangham discovered that phospholipids, when combined with water in the proper fashion, immediately form a bilayer sphere. One component of the structure has a water-based composition while the other component has a lipid-based composition. (See figure at left.)

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This extraordinary nutrient delivery system is especially advantageous for those nutrients with a molecular size that normally inhibits efficient absorption. Cellular absorption of most orally consumed coenzyme Q10 and glutathione, for example, may be 10% or lower, whereas liposomally transported coenzyme Q10 and glutathione may be absorbed at rates as high as 60% or more.

Water-soluble nutrients can thus be carried by the water-based (hydrophilic) component of the liposome while lipid-soluble nutrients can be transported by the lipid-based (hydrophobic) component.

*These statements have not been evaluated by the U.S. Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Take all supplements as suggested or as directed by your health care professional.

Many orally consumed nutrients may have cellular absorption rates in the range of 15% or lower. Those same nutrients in a liposomal delivery system, however, may be absorbed at rates as high as 60% or more.

VS Liposomes deliver micronutrients to cell

LIPOSOMAL DELIVERY OF NUTRIENTS

CELL Micronutrient

Fusion Endocitosis

Degradation of Liposome

Absortion

LIPOSOMES DELIVER MICRONUTRIENTS TO CELLS

Lipid Exchange

*These statements have not been evaluated by the U.S. Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Take all supplements as suggested or as directed by your health care professional.

Path of nutrient absorption via LifeOsome™ Liposomals LifeOsome™ Liposomals reache the blood via the Lymph Vassel SMALL INTESTINE

Lymph Vassel

LifeOsome™ Liposomals

Chylomicron

Peyer´s Patch M-cells Intestinal Mucosa

ADVANTAGES OF LIPOSOMALLY DELIVERED NUTRIENTS • Nutrients are rapidly dispersed and move quickly through the digestive system.

• No digestive breakdown needed to facilitate assimilation of nutrients.

• Nutrients are easily absorbed through the small intestine and transported intact through the bloodstream to the cells that need them.

• Nutrients are absorbed by and metabolized by the cells that need them without being subjected to digestive degradation.

*These statements have not been evaluated by the U.S. Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Take all supplements as suggested or as directed by your health care professional.

LIPOSOMES • Markedly improve the taste of certain nutrients, such as amino acids, that might otherwise be accompanied by a bitter taste.

• Target certain tissues or cell types by using certain lipids to form the phospholipid bilayer of the liposome.

• Release their contents when the liposomes have reached a predetermined temperature or pH value.

• Protect nutrients from acidic and/or enzymatic degradation in the stomach and intestine.

• Enhance intestinal absorption by coating the liposomes with complementary surface elements.

*These statements have not been evaluated by the U.S. Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Take all supplements as suggested or as directed by your health care professional.

CAN BE DESIGNED TO: • Protect encapsulated nutrients from premature oxidation.

• Evenly distribute fat-soluble substances, such as certain vitamins and antioxidants, that are generally not compatible with water-based products.

*These statements have not been evaluated by the U.S. Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Take all supplements as suggested or as directed by your health care professional.

Advantages of a Liposomal CBD Nanoemulsion Increases the bioavailability of active substances (CBD) It is not toxic or irritant by nature Better assimilation of fat-soluble nutrients Has very small particles that increment the contact surface that improve absorption No digestive breakdown needed to facilitate assimilation of ingredients (CBD).

Ingredients (CBD ) are rapidly dispersed and move quickly through the digestive system, for rapid effect, not offered by most CBD oil products.

CBD Liposomal por CBDsomal™ • Lipsomal CBD is offered in as a CBD Isolate at 99.5%, non THC infused (doesn’t get you “HIGH”).

• Made Organic Sunflower seed oil (NON GMO) or desired (MCT oil, Olive Oil, etc) • Available in natural or a range of flavors • Sweetened with Organic Agave Syrup or desired sweetener, or non sweet.

• Can be combined with liposomal Curcumin and vitamin E for joint relief, or other formulations if desired.

• You can infuse your natural drinks with effective results.

We offer from 250mg to 2000mg CBD per 30ml bottle As an example, the delivery of liposomal CBD can be felt with in minutes of dose.

*These statements have not been evaluated by the U.S. Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Take all supplements as suggested or as directed by your health care professional.

500mg - 16.6 mg per dose (1ml Dose/ 30 doses per bottle!)

1000mg - 33.3 mg per dose (1ml Dose/ 30 doses per bottle!)

CBDsomal por WCP We offer top CBD mg per ml at the best price in market We offer design by request formulation for optimal applications • Joint Pain • Insomnia/Better Sleep • Anti Stress • Chronic Pain relief • Proprietary formulations with Antioxidants We encourage you to try our formulations!

We offer you the opportunity of your own label (White Label) • We offer you the opportunity to have your own label and use your own tools of marketing.

• Products with Liposomal technology • We can develop your own CBD formulation (previously approved).

• Your own flavors and consistency.

• Your own label design with your brand.

*These statements have not been evaluated by the U.S. Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Take all supplements as suggested or as directed by your health care professional.

Questions at:

1.800.675.1845 info@cbdsomal.com