A DYSFUNCTION : HAIR LOSS FEMALE PATTERN Estrogens : Hair follicles have estrogen receptors (ERα and ERβ) The precursor Andrestenedione requires 3 enzymes : the 17-hydroxysteroid deshydrogenase, Aromase and the 5αreductase, to be converted in DHT. How estrogens influence FPHL has not been determined yet. Genetics : Endocrine reviews.
This is a polygenic disorder but the genes involved have not been found. Others : Blood circulation Stress, chemotherapy, malnutritionV PAGE 51