PROOF OF CONCEPT EX VIVO HUMAN SCALP MODEL Hair shaft elongation at day 6 Test protocol Human scalp skin samples obtained from plastic surgery were transferred into culture plates Pictures of the skin samples were taken on day 0, 3 and 6 and each hair shaft was labeled and measured at day 0, 3 and 6 BIO1631 formulated in a tonic or placebo was once daily applied topically on the skin samples (3 samples per treatment) The elongation of each growing hair follicle was obtained by calculating the difference in hair shaft length between day 6 and day 0 Hair follicles that did grow less than 50 ÂľM in 3 days were considered to be dead and were not considered
Human scalp culture
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