Array Laboratory Qualifications

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ARRAY-ARCHITECTS.COM


Table of Contents

Firm Profile . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 Laboratory Expertise . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 8 Case Studies . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 26

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Firm Profile Recognized as a leader in healthcare facility design, consulting and technology, Array offers knowledgebased, data-informed services, including planning, architecture, interior design, transformation and asset advisory services. Using lean as a foundation for a unique process-led approach, our deliverables use data and technology to leverage real-time patient and real estate market trends required by today’s healthcare organizations. Our devotion to a healthcare-exclusive practice springs from our belief in the power of design and technology to improve patient outcomes, maximize operational efficiencies and increase staff satisfaction.

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Healthcare comes in many forms. We know because we’ve designed for all of them. PAGE 5


Client Advocate

“I believe every design and planning decision can have an impact in supporting the successful operation of a healthcare facility.”

Laura Jensen, RA Principal & Project Architect




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Laboratory Project Experience


Miami, FL

Baptist Health South Florida Miami Cancer Institute & Research Lab Construction Cost: $20,000,000.00 Design Start: November 2015 Completion: April 2018

Collaborators Bliss & Nyitray JLL Healthcare Solutions Robins & Morton TGA Design TLC Engineering for Architecture

Project Information • 80,000 SF Fitout • Outpatient Oncology Services • Integrated Palliative Care • Outpatient Bone Marrow Transplant Treatment and Research • Bio-specimen Repository Facility • Genomic Testing and Research Lab • Clinical Trials • Administrative & Executive Offices

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Array was engaged to provide operational improvement, programming and design services for the fitout of a Cancer Research Building on the new campus of the Miami Cancer Institute for Baptist Health South Florida. The Institute, affiliated with Memorial Sloan Kettering, provides improved patient access to treatment and advanced protocols. The new program consists of clinical trials, a genomics lab, a USP 800 pharmacy, outpatient bone marrow transplantation, integrated palliative care and many sub-specialty clinics. As the delivery of oncology services drives a tighter connection between research and clinical care, this building represents the unifying program of spaces in that equation. Each workflow and each space was studied, tested, and crafted to represent the balance between integrated research and supreme patient care. Truly affording “bench-to-bedside” care through genomics testing and clinical trials, MCI also explored new avenues in other holistic realms of healthcare as it sought to redefine the characteristics and environment for palliative care. The new building stands as a hallmark for holistic, integrated cancer care.

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Bronx, NY

Montefiore Medical Center Moses Campus Lab Construction Cost: $5,000,000 Design Start: October 2013 Completion: Phase 1 - January 2015 Phase 2 - July 2016

Collaborators Cerami Associates Control Point Associates Kallen & Lemelson Reuther + Bowen Louis Sgroe Equipment Planning The Lighting Practice

Project Information • 17,500 SF Masterplan and implementation project • Lab Services consists of the following functions: – Clinical Pathology (Automated) – Anatomical Pathology • Incorporation of Lean Design Principals

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This 17,500 SF Masterplan and implementation project was designed to improve the work flow of the Pathology Department. This department currently functions on different locations at Moses Campus, involving different buildings. As the Montefiore System consolidates Reference Laboratory functions off-site, to maintain Stat Lab functions in the hospital, a 6,000 SF Rapid Response Lab is being developed to serve the Moses campus. The Rapid Response (Stat) Lab will include Clinical and Anatomical Pathology. Other functions remaining at Moses: Stem Cell Lab, Blood Bank, Neuropathology and Transfusion Array was challenged with programming the new labs in a phased, fully operational manner while achieving the desired result. The ultimate outcome was to create a workflow, appropriate with functional workspace modular casework for a growing business and changing technology.

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Leadership

“We begin each project with the goal of improving the healthcare experience by aligning the voice of the customer with a sustainable operational model. The projects we have ‘on the boards’ are illustrations of the progression from broad concepts to physical realities.” L. Kent Doss, AIA, LEED AP BD+C, Lean Six Sigma Black Belt Principal & Practice Leader, Design, Senior Regional Vice President, Mid-Atlantic



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Charlotte, NC

Johnson & Wales University Food Sciences Laboratory

Project Information: • 3,325 SF • Design Start: April 2018 Completion Date: November 2018 • Construction Cost: $1,686,763

Johnson & Wales University engaged Array to design spaces for a new Food Science

• 5 weeks for entire design process

program. Design from the initial meeting to construction documents was five weeks.

• Six months for entire construction

This included understanding the needs of their new program for the University’s

• Two new high plume exhaust fan

Charlotte campus.

• New Food Science Lab with five

Array assisted JWU in understanding not only how laboratories are designed, but also the intricacies and specifics required of laboratory projects throughout construction. All spaces also met all regulatory codes, including ADA regulations, ANSI and ASHRAE. The three new labs on the 5th floor required a new dedicated exhaust. The main lab has four fume hoods and one “observation” pass through hood that are exhausted through two new high plume exhaust fans. Various gases, air and vacuum were installed for specialized analyzers and experimentation. Island benches with lab gas, air and vacuum provide students with access to learn at the same time as the instructor. A Microbiology lab allows for food investigation and to learn about food illnesses. This space is equipped with a biosafety cabinet and autoclave.

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fume hoods, including one pass through (5th floor) • New Microbiology Lab (5th floor) • New Chemistry Prep Lab (5th floor) • Renovated Food Lab (3rd floor)


Philadelphia, PA

Veterans Affairs Medical Center Clinical Laboratory This technical/multi-phase project brings the proven team of Array, HERA, and HF Lenz together to implement upgrades at the Philadelphia Veterans Affairs Medical Center Clinical Lab. The core requirement for the project was to create an area central to the operations for the entire laboratory for the installation of an automated chemistry line, which would increase throughput for many of the functions performed by the clinical lab. Other project goals were to renovate the remainder of the

Project Highlights:

laboratories and update their equipment, improve flow within and between labs, and replace air-conditioning equipment, which was at the end of its lifecycle and no longer

• Size: 25,000 SF renovation

served the needs of the laboratory with its modern heat-producing equipment. The

• Design Start: 2011

project was designed to be constructed in six main phases and over 15 sub-phases.

• Completion Date: 2015 • Construction Cost: $7,270,000 • Expansion of microbiology, chemistry and toxicology • Expansion of waiting area and Director’s office • Improvements to employee lounge and administrative office • Finish upgrades throughout laboratory • Upgrade mechanical

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MidAtlantic, US

Confidential Client Regional Clinical Lab

Construction Cost: $30,000,000 Design Start: September 2016 Completion: June 2021

Consultants Ex;it KPFF / ConXtech Leach Wallace LerchBates Mortland Planning & Design VIKA WSP WZG

Project Information • 65,000 SF phased for new lab construction, demolition, and existing building expansion and renovation • Central processing • Core lab (chemistry, hematology, immunology, coagulation, flow cytometry, urinalysis, and Center of Excellence for testing and training), bacteriology, molecular diagnostics, TB-mycology and blood bank • Pathology: accessioning, gross anatomy/tissue processing, histology and cytology • Offices, Conference Rooms, Staff Amenities and Support Spaces • Slated to earn LEED Gold certification

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Array was engaged to help address significant growth in the Mid-Atlantic region and align our client’s lab operations with their national strategy. The resulting regional expansion/lab alignment project involves the development of a long-term replacement facility on the same site as the aging existing facility - maintaining operations on site throughout construction. The new facility is planned and designed to support long-term membership and growth within the region. The Array team worked with client stakeholders to develop a state-of-the-art laboratory utilizing robotics and advanced functional planning techniques that have been developed as part of the client’s nationwide System-wide improvement strategy. The solution has built-in expansion capabilities for laboratory functions while also accommodating related administrative functions. In addition, conference and training spaces are included in the design to address future needs of the region. The building design and materials palette was selected to reflect a duality of functions. The materials are both “high tech” (metal and glass) as an expression of the advanced technologies being utilized in the lab, as well as “high touch” (wood and stone) to provide a human-scaled and familiar environment to the staff who occupy the space. The public will experience it as a part of the urbanizing fabric of the region. The project is designed to achieve LEED Gold certification by the USGBC.

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Healthcare Interiors

“Laboratory interiors need to look toward the future. The design should celebrate flexibility and effortlessly adapt to the continuously evolving needs of equipment, workflows and most importantly, staff.” Clairanne Pesce, CHID, WELL AP, LEED AP ID+C Senior Interior Designer



Columbus, OH

The Ohio State University Molecular Pathology Laboratory Construction Cost: $2,600,000.00 Design Start: May 2017 Completion: October 2018

Collaborators Advanced Engineering Consultants Bergman KPRS Lawhon & Associates, Inc.

Project Information • 17,200 SF phased renovation • 3 separate phases of work (to continue operations) • 4 separate laboratories combined into 1 consolidated laboratory. • Consolidation and relocation of over eighty minus 80 freezers and refrigerators

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The Ohio State University Wexner Medical Center’s (OSUWMC) Molecular Pathology Department is comprised of both laboratory and administrative offices. The existing facility is located remotely from the main campus in a 1980’s building that houses several OSU tenants, which didn’t meet the current staffing, future staffing (potentially tripling in size) and throughput needs. In addition, the circulation separations divided the department, deliveries and staff were intermingling and there were several infrastructure issues to address. With public corridors causing divisions between the main Molecular Pathology Lab functions (Accessioning, PrePCR, RNA, Post-PCR and FISH), OSUWMC wanted to consolidate and integrate all departments into a more efficient Molecular Pathology department. The goal was to consolidate and streamline as many functions as possible, from deliveries to lab process flows and create larger more open spaces for future flexibility. Budget and code restrictions did not allow for the entire department to be combined. However, Array was able to close off certain corridors and combine many of the spaces, which mitigated most of the flow issues. The team then reorganized these spaces in a more efficient layout, with new modular laboratory casework and table systems that also provided future flexibility. This increased efficiency and maximized throughput of the department. This project also included enabling projects involving a freezer consolidation study, more electrical capacity and relocation that added future capacities, including new workstations for over 60 staff members, and a refresh of finishes in several OSU’s newly-configured Molecular Pathology/PCR department space includes various lab and support functions for their current increased capacity needs and future growth.

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Mt. Vernon, NY

Montefiore Medical Center Off-Site Central Laboratory Construction Cost: $39,000,000 Design Start: October 2013 Completion: Design Only

Collaborators Kallen & Lemelson Reuther & Bowen

Project Information • 112,000 SF Renovation • Incorporation of Lean Design Principles – Reference Lab consists of the following functions: - Medical Pathology (Autopsy/Morgue) - Clinical Pathology (Automated) - Mass Spectrometry - Anatomical Pathology - Microbiology - Electron Microscope Lab - Molecular Infectious Disease - Genetics/Genomics Services

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- Cytogenetics

- Molecular Pathology


Montefiore Medical Center strategized to consolidate Pathology laboratory functions in an off-site facility to accommodate the changing industry, technology developments and their expansion plan. Montefiore commissioned Array to centralize four laboratories to one location into a former four-level warehouse. The building incorporates a 24/7 Reference Lab and the System’s “Center of Diagnostic Medicine.” Montefiore’s teaching component will also be located in the facility for attending pathologists, residents and fellows. A Phlebotomy space will be provided for patients. The design criteria was to create a lab that is efficient and non-cellular. With the goal of transforming their Laboratory and Pathology services to improve patient care, teaching, training and research, Montefiore strives for knowledge-sharing spaces which encourage collaboration. The consolidation of the services to one location provides the opportunity for expertise, collaboration and interaction. The reference Lab consists of Medical Pathology (Autopsy/Morgue), Clinical Pathology (Automated), Mass Spectrometry, Anatomical Pathology, Microbiology, Electron Microscope Lab, Molecular Infectious Disease and Genetics/Genomics Services.

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Laboratory Case Studies


Project Management

“Architecture is about relationships. Relationships with spaces, objects and most importantly—people.”

Ron Evitts, AIA, LEED AP, Lean Pracitioner Principal & Engagement Manager



Case Study: Centralized Laboratory Services A Deeper Look The Pathology Lab serves as an important place of inquiry into the intricacies and characteristics of diseases to help determine proper diagnosis. The Pathology Lab is also a place of learning for medical students and medical professionals. Having efficient design and modern technology not only makes for a well-run lab to aid diagnostic services for clinicians and hospitals, but enhances the ability to perform leading edge research. With many Pathology Labs encapsulating a multitude of pathological testing, design plays a vital role in creating an organized, centralized and knowledge-sharing space.

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Centralizing Services CHALLENGE

Key Drivers for A Consolidated Laboratory With eight locations clustered in and around New York City, a well-respected healthcare

Our client needed to consolidate Pathology Lab services into a centralized location to accommodate a changing industry while keeping the services operational. The new lab also had to accommodate space for teaching and training attending pathologists, residents and fellows.

system is one of the most prominent medical providers and academic health systems in the city. With functions dispersed throughout locations, however, the System came to Array to help consolidate laboratory functions, a need determined by changing tides in the healthcare industry and new developments in technology as well as a need to accommodate a growth in the health system and their patient volume. Centralizing services will allow for new workflows and process improvements around new automated technology that could not be incorporated appropriately in existing spaces or floor plates. The plan was to develop a contemporary Reference Pathology Laboratory, servicing

SOLUTION By choosing an off-site location, the healthcare facility planned to house all pathology facets to complement a changing healthcare industry, including a 24/7 Reference Lab and the Center of Diagnostic Medicine. Using a Lean project delivery method ensured that an accelerated schedule could be met and kept hospital-based lab functions operational.

facilities in Westchester County and Bronx, NY, within a four-story building in Mount Vernon, NY. The interior renovatation for medical laboratories included new elevators, all new HVAC, Electrical, Plumbing, Fire Protection, Fire Alarm, Security, IT/Telecom, toilets, renovated stairs and egress. Core labs services to be centralized at the 112,000 SF Mt. Vernon location include: Medical Pathology, Clinical Pathology, Mass Spectrometry, Anatomical Pathology, Microbiology, Electron Microscope Lab, Molecular Infectious Disease and Genetics/Genomics Services including Cytogenetic and Molecular Pathology. Having these services encapsulated under one roof encourages collaboration, research and enhances expertise. The goal of this project is to centralize lab services for efficient design, an efficient construction process and simplified service. Another benefit of centralizing lab services is found in streamlining services which can lead to time and capital gains.

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Current Conditions Having recently acquired new hospitals, there was an opportunity for our client to utilize existing hospital space for patient services and consolidate four laboratories into one location – a former four-level warehouse. The retrofit of the 112,000 SF core and shell of the warehouse along with the fitout of the lab functions will take place with minimal changes to the site. The brick exterior will remain and minimal site changes will help to stay within target dates of our accelerated schedule.

Accelerated Schedule The schedule is fast-tracked to accommodate future services intended for the spaces being vacated by the labs. For example, with the transfer of lab services from the main campus, space can become available to expand patient services within the pediatric program, a growing service line. To maintain stat lab functions at the hospital, a 6,000 SF Rapid Response Lab is being developed to serve the campus.

A Trending Model Patient care, teaching, training and research all benefit from this new space. Adaptively reusing a shuttered warehouse, those dedicating their healthcare careers to advancing science and medicine will relish the opportunities to collaborate as never before in a strategically-conceived space specifically for their needs. By off-siting lab services and expanding hospital-based services at each facility, increases in patient satisfaction and market-share are expected. Being able to provide appropriately-sized departments in the newly-acquired square footage will increase functions and fulfill requests from staff for optimal work environments. Investing in what many consider a back-of-house function and giving it the space and means to expand and prosper will engage staff, clinicians and patients in a unique facility designed specifically to their needs.

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Implementation Modern Design for Labs and Support Spaces The building height volume and floor area will remain unchanged while the rooftop equipment will be replaced with new mechanical and electrical services. An emergency generator will maintain power during interruptions. Windows, curtain walls and doorways will be replaced, along with replacement of all glazing.

The Mt. Vernon Pathology Lab represents a shift in healthcare design, consistent with the System’s standard of design quality. Also significant is that the spaces typically concealed from the patients are designed with as much thought and intention as if they were to be high-end patient areas. Highlighted with a soothing color palette, the interior spaces are intended to support efficiency and focus as well as to attract and retain staff

To ensure safety and efficiency, the Mt. Vernon Lab will have one

with an enjoyable work setting. Sit-to-stand adjustable work

shared entrance for staff and patients with separate entrances

space will be installed to accommodate a variety of uses and

and egress for materials, trash, waste, and courier service for

individual preferences. Creating continuity throughout the lab

receiving specimens / autopsy delivery.

and a consideration of interior views from the exterior were carefully considered.

Natural wood and stone finishes have been incorporated into the interior design to offer a timeless sophisticated and attractive feel. The design also articulates areas for quiet independent work and studying or collaborative work with interior conference rooms outfitted with modern furniture, enhanced acoustic ceiling tiles and glass storefronts. Other staff amenities will include an exercise space with showers, a staff cafe and outside seating areas for breaks and team meetings in nice weather.

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Case Study: Molecular Pathology Laboratory A Deeper Look The Ohio State University Wexner Medical Center’s (OSUWMC) Molecular Pathology Department is experiencing a lot of growth. Because of this, they are facing facility, operational and staffing challenges. With a staff of over 75 people and growing, they are expecting to triple in size. In order to accommodate this growth, updates and consolidations were required in several laboratory, office and support spaces, along with a larger cafeteria space. OSUWMC requested the services of Array Architects to assist with helping them accommodate the growth, improve process flows and allow for updated infrastructure and capacity needs.

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Streamlining Workflows CHALLENGE The existing facility is located remotely from the main campus in a 1980s building that houses several OSU tenants. The facility, as is, didn’t meet the current staffing that is projected to triple in size and testing throughput needs. In addition, existing circulation separations divided the department and several infrastructure issues needed to be addressed.

Client Profile The Ohio State University Wexner Medical Center (OSUWMC) is a multidisciplinary academic medical center located in Columbus and is on the main campus of The Ohio State University. More than 50,000 inpatients receive medical care annually from OSUWMC, who manages more than one million patient visits each year. The Molecular Pathology Department provides clinical molecular diagnostics for a wide range of cancers and other heritable disorders. They provide cutting edge, clinically responsible and cost-effective diagnostics for the patients of Ohio and beyond. Molecular Pathology is a medical specialty that seeks to integrate microscopic findings with

SOLUTION

the genetic changes associated with diseases such as cancer and inflammatory conditions.

Array was able to create a more streamlined workflow by combining and reorganizing spaces for more efficient layouts. This also included the addition of new modular laboratory casework and table systems that provide flexibility. With this better allocation and implementation of space, it will improve workflows and create efficiencies.

detection of the cancers and provides help in selecting therapies. At this facility, they test

In cancer patients, this work includes more precise diagnostic classification, improved early cancer assays and support clinical trials with advanced DNA sequencing methods. The ongoing challenge of Molecular Pathology is to speed the practical application of genomics knowledge emerging from research labs and national initiatives to clinical decision-making in each patient. This involves computer-assisted analysis of sequence data and new methods to display results of genetic tests in the medical record.

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FIGURE 1: First floor all phases

Selective Demolition and Phasing Due to the 24 / 7 nature of clinical laboratory testing for increased patient satisfaction and more accurate outcomes, the logistics of a renovation project within an existing (and outdated building) can be complex. Add to that the selective nature of the overall scope while continuing to keep several departments operational. There are also other departments that occupy this facility, so keeping the required means of egress intact while also maintaining access and operations for their areas was also a concern.

Ultimately, these renovated

On these types of projects, more care is taken to account for all the existing

spaces need to remain

conditions to accurately reflect the selective demolition and renovation. As

operational. Therefore,

a result, phasing became a very important part of this project. This included

the coordination from

several temporary partitions and dust barriers, protecting diffusers and grills while still maintaining negative air pressures and carefully coordinated shut

investigation of the existing

downs, including addition of new breakers in electrical panels and removal of

conditions all the way through

electrical items that share live circuits.

execution is crucial and takes a

Three separate phases of work (figure 1) were needed so operations at

collaborative team to execute.

OSUMC could continue without interruption.

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Lab Spaces on First Floor

Project Highlights

With public corridors causing divisions between the main

• 3 separate phases of work (to continue operations)

Molecular Pathology Lab functions (Accessioning, Pre-PCR,

• 4 separate laboratories combined into 1 consolidated

RNA, Post-PCR and FISH), OSUWMC wanted to consolidate and integrate all departments into an overall more efficient Molecular Pathology department (page 44 illustration). The goal for the first floor lab spaces was to streamline the

laboratory. • Consolidation and relocation of over eighty minus 80 freezers and refrigerators

Results

connection for the flow of PCR work. This was achieved by

The goal was to consolidate and streamline as many

creating openings from one space to the next. There were

functions as possible, from deliveries to lab process flows and

many factors to consider, including sensitive instrumentation in

create larger more open spaces for future flexibility. Budget

operation, ongoing cancer testing, paths of egress and security.

and code restrictions did not allow for the entire department to be combined.

After Array carefully surveyed the spaces, it was determined that an intermediate corridor could be removed so that four labs

Despite this, Array was able to better allocate space and

could be combined into one large open space. This allowed for

implement better workflows that improved efficiencies.

not only current growth needs and better collaboration, but also for future flexibility. The next steps in the PCR process flow were also considered to allow for better continuity. In the Post-PCR lab, several walls were removed to again open up the space and allow for more growth. These areas were especially challenging because certain genetic analyzers are sensitive to not only dust, but also vibration. If the renovation work was not carefully

The Ohio State University’s newly-configured Molecular Pathology/PCR department space includes various lab and support functions for their current increased capacity needs and future growth.

Tools

considered, it could cost in the tens of thousands to recalibrate

Array used several tools to keep all the changing information

the instrumentation.

current, including BIM (Revit 2017), Bluebeam Studio and Skype, along with weekly Action Item lists and Owner calls,

To further reduce movement, improvement of the flow between

to address anything outstanding and keep the project moving

the wet and dry lab spaces was achieved by adding a door from

forward. Utilizing technology, including real-time edits, helped

the FISH Prep to the FISH screening area. This allowed staff to

the entire design team and clients not only see the updates

move between the two lab spaces while still ensuring temperature

live, but also helped keep track of all team decisions made.

and humidity control between each space remained independent. Overall, these renovations increased efficiency and maximized throughput of the department.

Support Spaces • In addition to laboratory space renovations, this project also included enabling projects involving renovations of: • The main staff cafeteria to accommodate lab staff, so they have a dedicated place for food and drink consumption (figure 3). • A freezer consolidation study for more electrical capacity. • Relocations which added future capacities, including new workstations for over 60 staff members. • Refresh of finishes in several areas and locker areas.

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Boca Raton / Boston / New York City / Philadelphia / Washington


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