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In This Issue

On the Cover

Graphene, a carbon atom monolayer of incredible strength and conductive properties, is poised to be a major player in the future of technology. Turn to page 19 to read Zaki Shafi’s review of this new Nobel Prize-winning material.


9 Discovering Topology with




19 President Noel Joseph B.S. in Pharmacology, 2012

Senior Editors Polina Pinkhasova Olesya Levsh Faye Marie Vassel

Vice President Zaki Shafi

Staff Writers Faye Marie Vassel Zaki Shafi Olesya Levsh Polina Pinkhasova Contributing Writers Karen Bulaklak Rana Said Artem Serganov Amy Patel Maha Mamoor Nadya Peresleni Kazi Ullah Layout Editors Sam Kilb Nadya Peresleni

Dr. John Milnor

Micro RNA and its Tremendous Role in Cancer

Poliovirus: A Promising Candidate for Oncolytic Treatment of Neuroblastoma

Editor-in-Chief Nadya Peresleni B.S. in Biochemistry, 2011

Associate Editors Zaki Shafi Rob Castellano Steven Leigh Stephanie Jones Malack Hamade Ida Li

Exploring Gustation and Olfaction with Dr. Fontanini

Web Editor Maria R. Stupnikov Copy Editors Sam Kilb Yousra Yusuf Advisory Board Dr. Robert Haltiwanger Dept. of Biochemistry and Cell Biology Dr. Harvard Lyman Dept. of Biochemistry and Cell Biology A special thank you to Isaiah Schuster, YIR President 2009-2010, for his involvement with the journal and its staff throughout the entire academic year, and to Alexander Chamessian, YIR founder and President, 20082009, for his continual support.

Cover article: Graphene: The Possibilities are Endless

Gene Therapy and the Power of Chemoselective Vector Modification

A Scientific Breakthrough

The Crystallization of Ribo- switches: Potential Targets for Antibiotics

Enhancement of Reactivation of Murine Gammherpesvirus 68 from Latency Through NF-kB Inhibition

Death Associated with Activation of MAP and PI3 Kinases: The Role of TRAF4

Inhibitors of Serine Proteinases, Matrix Metallo- proteinases and Histone Deacetylases: Thermorubin, COL-308, Myricetin, and Tellimagrandin


25 Farewell to Diabetes: 27 31

36 Ethanol-Induced Epithelial Cell 41



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