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An ACCESS-2-TECHNOLOGYSM Presentation... © 2 0 0 5 - 0 9

X e n n o v a t e

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Xen18 Hydrocolloids Š 2 0 0 5 - 0 9

X e n n o v a t e

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xm18c Absorbs more, longer... !

xm18c most absorptive formulation available | World leader in absorption

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Compared to seven leading brands with results at right

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The “competitive mean� data demonstrates absorption failure in as little as three hours of submersion

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Xen18 still absorbing after three days of submersion


Highlights of Xen18 Hydrocolloid Adhesive Technology... Why...

How...

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Integration | No melting

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Opposite of “DIS-integration” | Stays intact

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Long-lasting

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Cohesive | 3D dispersion tightly bound

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Thinner profile

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Reduced residue

Three levels of absorption provides 2-3 times the absorption of major brands

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Little or no “edge-bleed”

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Can extrude down to ~12 mils | ~300!

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Faster & easier changes

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EverLift adds even more cohesive support

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Caregiver time savings

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Lower “system cost”

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Odor-free

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No animal-derived components [odor]


Compare Three Xen18 Formulations...

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xm18c | Super AB | Represents Xennovate’s oldest formulation with the greatest absorptive capacity | All the competitive absorption studies employed this formulation xm18w | First AB | Specially formulated in response to a USA wound products customer requiring more initial adhesion, while accepting somewhat less absorptive capacity, although still more than any of key competitors xm18o | OTC | Specially formulated as an ostomy adhesive, requiring skin evaporation absorption only Note comparative metrics in table under graphic

Compare xm18 Formulations 600%

Weight as Percent Dry Weight

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500% 400% Xennovate Super 18C

300%

Xennovate First 18W Xennovate OTC 18Wo

200% 100% 0%

Ă˜

1-H

3-H

6-H

12-H

1-D

2-D

3-D

Xennovate Super 18C

0%

73% 205% 333% 405% 444% 452% 477%

Xennovate First 18W

0%

190% 236% 282% 327% 329% 337% 356%

Xennovate OTC 18Wo

0%

174% 203% 232% 260% 260% 264% 279%

Time

Attribute

xm18C

xm18w

xm18o

Absorption @ 3 Days

477%

356%

279%

Absorption @ 12 Hours

405%

327%

260%

Initial Adhesion

75 gms

140 gms

125 gms

Adhesion @ 30 mins

210 mgs

215 mgs

210 mgs

Highest & Best Use

Heavily exudating wounds

Exudating wounds

OTC strips | Ostomy

Relative cost

122%

95%

84%


Compare Three + One Xen18 Formulations...

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xm18e | ENCORE | Added to product line as an evolutionary outcropping of the need for an aggressive skin attachment adhesive with great “shear” adhesion, enabling devices to be attached to the skin

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Also can be used for onepiece ostomy attachments where wear times are no more than 3-4 days for pouches

Attribute

xm18C

xm18w

xm18o

xm18e

Absorption @ 3 Days

477%

356%

279%

289%

Absorption @ 12 Hours

405%

327%

260%

152%

Initial Adhesion

75 gms

140 gms

125 gms

120 gms

Adhesion @ 30 mins

210 mgs

215 mgs

210 mgs

220 gms

Highest & Best Use

Heavily exudating wounds

Exudating wounds

OTC strips | Ostomy

Skin Attachment

Relative cost to Mean

132%

103%

91%

74%


Line Extensions for Xen18 !

See EverLift RemovEZ + PULL-TAB elsewhere in Movie or in Brief

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Most recent technical advance for Xen18 is ProThin Ultra 12 !

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We have completed development of extruded hydrocolloids with or without EverLift at less than 12 mils thin [0.012 inches or " 300!]

See our HiTek presentation elsewhere, which highlights many innovative options open for co-development with Xennovate Medical !

Most of our innovation surrounds our proprietary hydrocolloid adhesive

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We will respond to your needs quickly and relatively inexpensively

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We primarily seek new manufacturing output via our inventions

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Many of our innovations have the high likelihood of patenting for the benefit of both Xennovate and our co-developers


THANK YOU FOR YOUR TIME & ATTENTION

— Trademarks owned by Xennovate Medical LLC include —

Xennovate | XennMed | XenMed | Xen18 | xm18 | EverLift NearClear | ProThin Ultra | RemovEZ | UriSeal | Vortex ZDS © 2 0 0 5 - 0 9

X e n n o v a t e

M e d i c a l

L L C .

A l l

R i g h t s

R e s e r v e d .


THANK YOU FOR YOUR TIME & ATTENTION

l l a s ’ That folks! — Trademarks owned by Xennovate Medical LLC include —

Xennovate | XennMed | XenMed | Xen18 | xm18 | EverLift NearClear | ProThin Ultra | RemovEZ | UriSeal | Vortex ZDS © 2 0 0 5 - 0 9

X e n n o v a t e

M e d i c a l

L L C .

A l l

R i g h t s

R e s e r v e d .


Xennovate Medical Hydrocolloids