Lab+Life Scientist Jan 2014

Page 27

what’s new

Next-generation sequencing system

High-throughput assays for mitochondrial function

Thermo Fisher Scientific has an-

Enzo Life Sciences’ Mito-ID assays work together to

nounced the Ion PGM Dx Sys-

assess the dynamic interaction between mitochondrial

tem, developed using Ion Torrent

respiration and glycolytic flux.

next-generation sequencing (NGS) technology.

Mito-ID Oxygen and pH Sensors are high-throughput assays with easy mix-and-measure protocols. The

The product enables clinical

sensitive, reversible probes provide real-time analysis

laboratories to more easily develop

and are compatible with standard fluorescence plate

and implement next-generation

readers.

sequencing diagnostic assays.

Mito-ID Extracellular O2 Sensor Kits are oxygen-sensitive phosphorescent probes which can

Providing accurate genetic variant

be used to assess O2 consumption by cultured cells, isolated mitochondria, microorganisms,

analysis with as little as 10 ng of

tissues and enzymes. The probe increases in signal intensity with O2 consumption.

sample DNA, the system is suitable for the clinical and diagnostic

The Mito-ID Extracellular pH Sensor Probe is a pH-sensitive phosphorescent probe which can

communities.

be used to monitor cellular acid extrusion. It provides a simple mix-and-read protocol for 96well microplates and is amenable to standard fluorescence plate readers (Ex/Em 340/615 nm).

The system includes the instru-

The Mito-ID Membrane Potential Cytotoxicity Assay Kit is a real-time mitochondrial mem-

ments, GMP reagents and software

brane potential assay, said to be 10x more sensitive than JC-1 with good aqueous solubility.

controls necessary to establish high-

The product features photostable dual-emission dye and no-wash/no-medium removal. It is

performing next-generation clinical

suitable for high-throughput applications; separate Mito-ID Red/Green assays are available

sequencing workflows.

for the detection of mitochondrial mass.

Thermo Fisher Scientific

United Bioresearch Products Pty Ltd

www.thermofisher.com.au

www.unitedbioresearch.com.au

I M A G I N G // C H E M I D O C™ TO U C H I M AG I N G SYS T E M

Introducing the New ChemiDoc™ Touch Sensitive, precise, and flexible, the ChemiDoc™ Touch Imaging System is a complete solution for gel and western blot imaging. • Equal to film in sensitivity and resolution • Superior to film in signal-to-noise ratio and linear dynamic range • Highly intuitive software and user interface

With this seamless integration of high-quality imaging and quantitative tools, the path from experiment to usable data has never been so clear or streamlined. Arrange a demonstration today.

www.LabOnline.com.au | www.LifeScientist.com.au

LAB+LIFE SCIENTIST - January 2015 | 27