what’s new
Next-generation sequencing system
High-throughput assays for mitochondrial function
Thermo Fisher Scientific has an-
Enzo Life Sciences’ Mito-ID assays work together to
nounced the Ion PGM Dx Sys-
assess the dynamic interaction between mitochondrial
tem, developed using Ion Torrent
respiration and glycolytic flux.
next-generation sequencing (NGS) technology.
Mito-ID Oxygen and pH Sensors are high-throughput assays with easy mix-and-measure protocols. The
The product enables clinical
sensitive, reversible probes provide real-time analysis
laboratories to more easily develop
and are compatible with standard fluorescence plate
and implement next-generation
readers.
sequencing diagnostic assays.
Mito-ID Extracellular O2 Sensor Kits are oxygen-sensitive phosphorescent probes which can
Providing accurate genetic variant
be used to assess O2 consumption by cultured cells, isolated mitochondria, microorganisms,
analysis with as little as 10 ng of
tissues and enzymes. The probe increases in signal intensity with O2 consumption.
sample DNA, the system is suitable for the clinical and diagnostic
The Mito-ID Extracellular pH Sensor Probe is a pH-sensitive phosphorescent probe which can
communities.
be used to monitor cellular acid extrusion. It provides a simple mix-and-read protocol for 96well microplates and is amenable to standard fluorescence plate readers (Ex/Em 340/615 nm).
The system includes the instru-
The Mito-ID Membrane Potential Cytotoxicity Assay Kit is a real-time mitochondrial mem-
ments, GMP reagents and software
brane potential assay, said to be 10x more sensitive than JC-1 with good aqueous solubility.
controls necessary to establish high-
The product features photostable dual-emission dye and no-wash/no-medium removal. It is
performing next-generation clinical
suitable for high-throughput applications; separate Mito-ID Red/Green assays are available
sequencing workflows.
for the detection of mitochondrial mass.
Thermo Fisher Scientific
United Bioresearch Products Pty Ltd
www.thermofisher.com.au
www.unitedbioresearch.com.au
I M A G I N G // C H E M I D O C™ TO U C H I M AG I N G SYS T E M
Introducing the New ChemiDoc™ Touch Sensitive, precise, and flexible, the ChemiDoc™ Touch Imaging System is a complete solution for gel and western blot imaging. • Equal to film in sensitivity and resolution • Superior to film in signal-to-noise ratio and linear dynamic range • Highly intuitive software and user interface
With this seamless integration of high-quality imaging and quantitative tools, the path from experiment to usable data has never been so clear or streamlined. Arrange a demonstration today.
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LAB+LIFE SCIENTIST - January 2015 | 27