Back cover photo: Genetic ablation of the Drf1 gene gives rise to hypermotile cells The Drf1 gene was genetically ablated by homologous recombination. Drf1– cells become hypermotile and produce large lamellipodia. These observations suggest that Drf1 genes participate in the regulation of motility and that they negatively regulate motility. (Peng, Swiatek, and Alberts)
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