Upstate Health, Summer 2019

Page 24

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SCIENCE IS ART IS SCIENCE IS ART IS SCIENCE IS

A research team at Upstate identified an unusual form of neurodevelopmental delay that is caused by deficiency in a protein called paxillin. They have discovered that brain cells that are deficient in paxillin move more slowly than healthy brain cells, and there is a corresponding delay in the development of the cerebral cortex. This tissue sample shows multiple layers of the cerebral cortex, which have been labeled red and green with specific histological markers.

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Researchers: Mamunur Rashid, Judson Belmont, David Carpenter, Christopher Turner, PhD, and Eric Olson, PhD.

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