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Cancer O u t co m e s 2012


Table of Contents 4-10 // Outcomes Data 4 // Colon Cancer 5–Year Survival 4 // Liver Cancer 5–Year Survival 5 // Lung & Bronchus 5–Year Survival 5 // Melanoma of the Skin 5 –Year Survival 6 // Breast Cancer 5–Year Survival 6 // Corpus Uteri Cancer 5–Year Survival 7 // Thyroid Cancer 5–Year Survival 7 // Prostate Cancer 5–Year Survival 8 // Brain (Excluding Benign Brain) 5–Year Survival 8 // Brain (GBM Only) 5–Year Survival 9 // Pituitary Gland 5–Year Survival 12 // Colorado’s Only Federally Designated Cancer Center


University of Colorado Hospital

is the leading academic medical center in the nation. University of Colorado Hospital (UCH) is recognized as the highest-performing academic hospital in the United States for delivering quality health care by the University HealthSystem Consortium for two years in a row, and is ranked as the best hospital in the Denver metro area and one of the best in the country by U.S. News & World Report. UCH is best known as an innovator in patient care and often is one of the first hospitals to bring new medicine to the patient’s bedside. The hospital’s physicians are affiliated with the University of Colorado School of Medicine, part of the University of Colorado system. Based at the expansive Anschutz Medical Campus in Aurora, Colo., UCH is where patient care, research and education converge to establish the future of health care delivery.

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34%

33% 27%

25%

UCH

15%

OUTCOMES data

12% 14%

12%

KEY

Colorado National

4%

Stage I*

Stage II

3% observed survival data 2003-2005 (AJCC 6th Edition) Stage IV

Stage III

*N  =  11  for  UCH

Colon Cancer 5–Year Survival

Colon Cancer - 5 Year Survival 88% 73%

78%

UCH

76% 67% 67%

58%

State

54% 55%

19%

Stage I*

Stage II

National

Stage III**

9% 10%

Stage IV

*N  =  16,  **N   9 **N = 19 *N ==  1 16,

Rectum & RectoSigmoid Junction Cancer - 5 Year Survival 70%

63%

UCH

79%

Liver Cancer 5–Year Survival 50%

57%

64%

State

National

61% 63% 59%

Liver

51%

49%

33% 32% Stage I* *N  =  11,  **N  =  14

UCH

Stage II** 25% 25%

Stage III

4%

*N  =  11

Stage II

Stage IV 18%

12%

Stage I

State National 14% 9% 11%

6%

2%

Stage III

2%

Stage IV*

*N = 11

Pancreas Cancer - 5 Year Survival UCH

19% 19% 4

13% 10%

State

National


Lung & Bronchus 5–Year Survival Lung & Bronchus Cancer - 5 Year Survival 56% 56%

UCH

46% 46% 45% 36% 36%

State

National

31% 31%

26% Lung & Bronchus Cancer - 5 Year 26% Survival 18% 18%

60%

11% 11% 11% 11%

UCH

State National 6% 7% 3% 2% 2% 3%

46% 44% Stage II Stage

Stage II 31% II 30%Stage 26%

Melanoma of the Skin - 5 Year Survival

Stage III III Stage

StageIV IV Stage

18% 11% 11%

92% 90% 91%

6% UCH

Stage I

Stage 68%II66% 68%

Melanoma of the Skin 5 –Year Survival

Stage III 65% 59% 55%

3% State

2% National

Stage IV

Melanoma of the Skin - 5 Year Survival 92% 90% 91%

UCH 68% 68% 66% Stage I

Stage II

65%

59%

State 7% 8%

National 13%

55%

Stage III

Stage IV*

*N  =  14

Breast Cancer - 5 Year Survival Stage I *N  =  14

Stage II

7% Stage III

8%

13%

Stage IV*

*N = 14

Breast Cancer - 5 Year Survival

5


UCH

KEY

OUTCOMES data

Colorado National

observed survival data 2003-2005 (AJCC 6th Edition)

Breast Cancer 5–Year Survival

Breast Cancer - 5 Year Survival 96%

92% 92%

90%

59%

Breast Cancer - 5 Year Survival 96%

92% 92%

Stage I

90%

UCH

85% 85%

State

69% 66% 47%

85% 85%

Stage II

26% National State 21%

UCH 69% 66% 59% Stage III

Stage IV 47% 26%

Corpus Uteri Cancer - 5 year Survival 89% 89% 88% Stage I

77% 76% Stage II72%

Corpus Uteri Cancer 5–Year Survival

71%Stage III 62%

UCH

Stage I

Stage II*

33% 71%

UCH

23% National State 16%

62%

52% Stage III

Stage IV** 33%

*N  =  13,  **N  =  12

23%

Stage I *N  =  13,  **N   =  12 *N = 13, **N = 12

6

National

52%

89% 89% 88% 72%

State

21%

Stage IV

Corpus Uteri Cancer - 5 year Survival 77% 76%

National

Stage II*

Stage III

16%

Stage IV**


47% 35% 37%

Stage I*

Stage II

Stage III

Stage IV

*N  =  16

Thyroid Cancer 5–Year Survival

Thyroid Cancer - 5 Year Survival 96% 98% 98%

86%

97% 96%

100%

94% 92%

UCH

State

68%

Stage I *N  =  16

Stage II*

Stage III*

National

57% 59%

Stage IV

*N = 16

Prostate Cancer 5–Year Survival

Prostate Cancer - 5 Year Survival 95%

94%

83% 83%

89% 91%

93% 93% 91% UCH

State

National

47% 35% 37%

Stage I* *N  =  16

Stage II

Stage III

Stage IV

*N = 16

Thyroid Cancer - 5 Year Survival 96% 98% 98%

86%

97% 96%

100%

94% 92%

UCH

State

68%

National

57% 59%

7


UCH

KEY

OUTCOMES data

Colorado

observed survival data 2003-2005 (AJCC 6th Edition)

Brain (Excluding Benign Brain) 5–Year Survival Brain (excluding Benign Brain) 5 Year Survival

Comparable national data for this type not available

70%

56%

UCH

57% 43%

Year 1

Year 2

49%

46% 37%

Year 3

State 45%

35%

32%

Year 4

Year 5

Brain (GBM Only) 5–Year Survival Brain - GBM Only 5 Year Survival 49%

UCH

State

36% 26% 14%

Year 1

8

Year 2

12%

7%

Year 3

11%

11% 5%

Year 4

4% Year 5


Pituitary Gland 5–Year Pituitary Survival Gland Comparable national data for this type not available

5 Year Survival

99% 96%

98%

98%

98% UCH

94%

93%

94%

State

93% 89%

Year 1

Year 2

Year 3

Year 4

Year 5

Brain (excluding Benign Brain) 5 Year Survival 70%

56%

UCH

57% 43%

49%

46% 37%

State 45%

35%

32%

9

Year 1

Year 2

Year 3

Year 4

Year 5


NCI CANCER CENTERS IN THE USA

= NCI Cancer Center = NCI Comprehensive Cancer Center = UCH, NCI Comprehensive Cancer Center

Colorado’s only federally designated cancer center tackles cancer from all angles The University of Colorado Cancer Center is the hub of cancer research in Colorado. We are a consortium of more than 400 researchers and physicians at three state universities and six institutions, all working toward one goal: translating science into cancer survivorship.

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Through collaboration and innovation, CU Cancer Center

University of Colorado Hospital, and the THRIVE clinic for

members discover, develop and deliver breakthroughs that improve

transitioning adult cancer patients back to primary care.

cancer care for people and companion animals. We focus on:

Cancer screening. The Colorado Colorectal Screening Program

Personalized care that embraces the best clinical practices of

is a national model for ensuring uninsured Coloradans who meet

prevention, diagnosis, treatment and survivorship.

certain financial and risk criteria receive colon cancer screening

• Innovative interdisciplinary research. • Premier clinical and scientific training. • Creative partnerships. Founded in 1988, CU Cancer Center is the only comprehensive cancer center designated by the National Cancer Institute in Colorado and the Rocky Mountain region. Our founding director, Paul A. Bunn, Jr., MD, led the organization until 2009. In 2010, Dan

and follow-up care at no cost to them. Molecular tumor testing. CU Cancer Center has developed tests that find specific gene defects that can be targeted with new drugs. These tests have positioned CU Cancer Center as a national leader for clinical trials of “targeted” drugs. Tumor Explants. CU Cancer Center is on the cutting edge of personalized cancer treatment, developing laboratory methods to test cancer therapy by explanting living cancers from patients

Theodorescu, MD, PhD, ushered CU Cancer Center into a new era.

into a special breed of mice. The mice receive different treatments

CU Cancer Center is headquartered on the Anschutz Medical

respond to.

Campus in Aurora, Colo., in the University of Colorado School of Medicine. Member institutions include University of Colorado Denver, University of Colorado Boulder, Colorado State University, University of Colorado Hospital, Children’s Hospital Colorado, Denver VA, Veterans Affairs Medical Center, Denver Health, National Jewish Health and the Kaiser Permanente’s Institute of Health Research. Our clinical outreach program extends throughout Colorado and neighboring states.

Highlights and Accomplishments CU Cancer Center is known clinically for its robust and diverse Phase I clinical trials program and personalized cancer treatment. Our scientific expertise ranges from understanding how chromosome structure controls cancer cell behavior, to understanding how the immune system impacts cancer. Other strengths include: Lung cancer care and research. CU Cancer Center is one of

to identify the drug combination that the patient’s tumor will best

Cancer clinical trials. With the largest human and companion animal cancer clinical trials programs in the region, CU Cancer Center provides patients across the state and region with access to cutting-edge cancer care. CU Cancer Center’s Phase I Trials program is the only program of its kind in the region. Structural biology. CU Cancer Center’s NMR spectroscopy and X-ray facilities are among the best in the world and have helped recruit world-class scientists to use them. The machines, housed in CU Cancer Center’s Structural Biology shared resource, help scientists solve structures of cancer molecules to develop drugs with precise molecular targeting. Animal cancer treatment and clinical trials. The Colorado State University Animal Cancer Center is the world leader in research and treatment of spontaneously occurring cancers in companion animals, especially dogs. CU Cancer Center’s members at CSU collaborate with researchers in human cancers, and clinical trials in dogs have led to new treatments for people.

the world’s best lung cancer research and treatment programs. We are the coordinating center for the Lung Cancer Mutations Consortium, funded by a $5.3 million American Reinvestment and Recovery Act Grand Opportunities grant. Cancer survivorship. We’re one of eight LIVESTRONG Cancer Survivorship Centers of Excellence and home to the region’s three full-scale cancer survivorship clinics: The HOPE clinic for young adult survivors of cancer at Children’s Hospital Colorado, the TACTIC clinic for adult survivors of childhood cancer at

Learn more: www.coloradocancercenter.org www.uch.edu coloradocancerblogs.org facebook.com/coloradocancercenter 11



Cancer Outcomes 2012