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Medical Professionals

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Endometrial Receptivity Array (ERA) Endometrial Biopsy

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Since the birth of the first in vitro fertilization (IVF) baby 40 years ago, the field of reproductive endocrinology has undergone major advances in medications, retrieval procedures, and laboratory techniques. Despite these innovations, the cumulative live pregnancy rate per egg retrieval is 35-48% for women 35 to 37 years old and 13-18% for women over the age of 40.

years, studies have shown this is not an accurate assessment. As a result, we may be transferring embryos at the inappropriate time. A test has been developed that directly evaluates the uterine lining for receptivity: endometrial receptivity analysis (ERA). This is a genetic test which uses a small sample • Comprehensive Fertility Care of a woman’s endometrial tissue to evaluate • InVitro Fertilization (IVF) whether or not the uterine lining is prepared and • Intrauterine Insemination is able to accept an implanting embryo. This test • Intracytoplasmic Sperm Injection (ICSI) analyzes the endometrial lining at the molecular • Preimplantation Genetic Diagnosis and Screening level, evaluating for 248 genes. It detects a • Egg Freezing specific genetic signature which identifies the • Donor Egg lining as being receptive for an embryo. If it is • Treatment for Recurrent Pregnancy Loss not ready (pre-receptive) or over-mature (post• Advanced Robotic Reproductive Surgery Even though we are able to obtain eggs and receptive), the test will denote changes required sperm to create an embryo, the live birth rate is to make the lining receptive. still less than 50 % nationally. The area that is In the era of personalized medicine, a “one still an enigma is the “window of implantation.” size fits all” policy is no longer acceptable. This denotes the appropriate time to transfer an With IVF, we individualize ovarian stimulation embryo to maximize the implantation potential protocols based on a patient’s/couple’s medical of an embryo. Over the years we have found situation. We now recognize the importance of that a specific sequence of events must occur for individualized uterine preparation protocols to an embryo to implant and grow. Currently, it is facilitate an appropriate uterine environment Pictured (L-R): preferable to transfer a blastocyst embryo, which Dr. Alan M. Martinez • Dr. William F. Zeigler to optimize treatment outcome. ERA is the begin your personalized occurs 5 days after fertilization. The Fertilization blastocyst (IVF) • Comprehensive Fertility Care Dr. Virginia A. Mensah • InVitro most objective and accurate test available today fertility treatment plan today • Egg Freezing is transferred into the uterine cavity and the • Intrauterine Inseminationfor diagnosing endometrial receptivity. It has Toms RiverDR. • Eatontown • Lawrenceville WILLIAM F. ZEIGLER embryo hatches out and makes direct contact Sperm • Treatment for Recurrent Pregnancy • Intracytoplasmic been used to define an altered “window of DR. ALAN M. MARTINEZ Loss with the uterine lining. WhenInjection it does, (ICSI) both the 732-240-3000 • FERTILITYNJ.COM DR. VIRGINIA A. MENSAH implantation,” and thus establish a personalized endometrium and the blastocyst adhere to each • Preimplantation Genetic • Donnor Egg protocol for each patient. It has been shown to be other. The embryo begins to undergo process Diagnosisa and Screening • Advanced Robotic Reproductive beneficial in improving reproductive performance Surgery TOMS RIVER • EATONTOWN • LAWRENCEVILLE of invasion to establish a blood supply with the in patients with recurrent pregnancy loss, IVF 732-240-3000 • FERTILITYNJ.COM mother. For this sequence of events to occur, failures, and unexplained infertility. the lining of theFREE uterusSECOND must haveOPINION a specific • FREE PHONE CONSULTATION • PERSONALIZED TREATMENT PLANS component; this is called receptivity. For more information call In the past, we would assess uterine receptivity Reproductive Science Center of NJ, indirectly using an ultrasound. The lining had Personalized Treatment Plans 732-240-3000. to be a specific thickness and pattern. In recent

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q Chicken Breasts With Grilled Pineapple and Tomatillo Salsa Grilled chicken topped with a delicious sweet and spicy combination of savory onions, sweet pineapple and rich tomatillo salsa (Serves 4)

2 Tsp olive oil ½ large sweet onion, cut into thick rings 8 fresh pineapple spears 1 ½ c tomatillo salsa (store bought, or make your own!) 2 Tsp cilantro, fresh, chopped 1 Tsp lime juice 4-6 oz chicken breasts, boneless, skinless (or your personal preference)

oil then season with salt and pepper. Grill, flipping once, until just charred in spots and softened, 6 to 8 minutes total; transfer to a plate. When cool enough to handle, roughly chop onions and pineapple and transfer to a bowl. Add tomatillo salsa, cilantro, lime juice, salt and pepper and toss gently to combine. Brush chicken all over with remaining tablespoon of oil and season with salt and pepper. Grill, flipping once, until deep golden brown all over and cooked through, 8 to 10 minutes total. Transfer chicken to a platter, spoon grilled pineapple salsa Oil grill grates and preheat grill to mediumhigh over the top and serve immediately. heat. Brush onions and pineapple with 1 tablespoon of the

Recipe inspired by Stephanie Hopkins, Cutting Board Creations

The County Woman Magazine www.TheCountyWoman.com

January/February 2019

Profile for The County Woman

Ocean County Woman - January/February 2018  

The County Woman ™ is part of a nationally syndicated publication and has been around for over 31 years. There are over 371 other counties t...

Ocean County Woman - January/February 2018  

The County Woman ™ is part of a nationally syndicated publication and has been around for over 31 years. There are over 371 other counties t...

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