for heart, fitness may surmount genetics
Exercise reduces the risk of heart disease, even in people who are genetically prone to it, according to large new study. Researchers focused solely on the role of physical fitness, tracking about a half million adults who did not have heart disease at the start of the study. They tested for genetic susceptibility and then placed participants in three groups based on fitness levels. Evaluations were done over the next six years to see which people developed heart disease. Many participants did develop heart disease, especially those who were genetically prone. But the men and women who had the highest aerobic fitness levels cut their risk in half. “What this tells us is that you can mitigate some of your genetic risk for heart disease by being fit, no matter how high that risk may be,” researcher Erik Ingelsson, MD, PhD, told The New York Times. He added that most of the fittest people “were not athletes,” but did moderate exercise such as walking. “Associations of Fitness, Physical Activity, Strength, and Genetic Risk with Cardiovascular Disease . . .” by E. Tikkanen et al., Circulation, 4/9/18 l “To Slash Your Risk of Heart Disease, Keep Moving” by Gretchen Reynolds, The New York Times, 4/18/18
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