Issuu on Google+


Nutrition_p1_pro1.indd 1

6/18/09 10:21:22 PM


Journal of Nutrition Association of Thailand

5

10

Vol. 43 No. 4 October - December 2008

14

38

Regular Editorial Nutrition Talk

4

ºÃóҸԡÒÃá¶Å§

Nutrition Icon

5

àÃ×èͧàŋҢͧâÀª¹Ò¡Ã... º¹àÊŒ¹·Ò§¡ÒþѲ¹Òà¾×èÍâÀª¹Ò¡Ò÷Õè´Õ º·ÊÑÁÀÒɳ¾ÔàÈÉ ÈÒÊμÃÒ¨ÒÏà¡ÕÂÃμԤس ´Ã.ÊÔÃÔ¹·Ã ¾ÔºÙŹÔÂÁ ·Õè»ÃÖ¡ÉÒÊÁÒ¤ÁâÀª¹Ò¡ÒÃáË‹§»ÃÐà·Èä·Â ã¹¾ÃкÃÁÃÒªÙ»¶ÑÁÀ¢Í§ÊÁà´ç¨¾ÃÐà·¾ÃÑμ¹ÃÒªÊØ´ÒÏ ÊÂÒÁºÃÁÃÒª¡ØÁÒÃÕ

10 TCN 2009 âÀª¹ÈÒÊμÏ...

¡ÒûÃЪØÁâÀª¹Ò¡ÒÃÃдѺâÅ¡ º·ÊÑÁÀÒɳ¾ÔàÈÉ ÃͧÈÒÊμÃÒ¨ÒÏ ´Ã.àÍÁÍà ÇÊѹμÇÔÊØ·¸Ôì »Ãиҹ¤³Ð¡ÃÃÁ¡ÒôŒÒ¹ÇÔªÒ¡Òâͧ¡ÒèѴ»ÃЪØÁ The 19th International Congress of Nutrition (ICN 2009)

Nutrition Trend

14 ¡ÒáÅÒ¾ѹ¸Ø¢Í§ÂÕ¹àÅ»·Ô¹

¡Ñº¡ÒÃà¡Ô´âä͌ǹ

Nutrition Research

17 »ÃÔÁÒ³à¡Å×Íá˪¹Ô´μ‹Ò§æ â¾ÅÕ¿‚¹ÍÅ á·¹¹Ô¹

áÅÐä¿àμ·ã¹¼ÅäÁŒä·Â

28 ¡ÒûÃÐàÁÔ¹¤ÇÒÁàÊÕ觡ÒÃä´ŒÃѺÊÑÁ¼ÑÊÊÕÊѧà¤ÃÒÐˏ¼ÊÁÍÒËÒÃ

¨Ò¡¡ÒúÃÔâÀ¤ÍÒËÒâͧà´ç¡¹Ñ¡àÃÕ¹ã¹à¢μàÁ×ͧ ¢Í§¡Ãا෾ÁËÒ¹¤Ã áÅÐà¢μª¹º·¢Í§¨Ñ§ËÇÑ´¹¤Ã»°Á

Nutrition Review

38 Melanocortin-4 receptor ¡Ñºâä͌ǹ Nutrition Forum

41 ¢ŒÍºÑ§¤ÑºÊÁÒ¤ÁâÀª¹Ò¡ÒÃáË‹§»ÃÐà·Èä·Â

ã¹¾ÃÐÃÒªÙ»¶ÑÁÀÊÁà´ç¨¾ÃÐà·¾ÃÑμ¹ÃÒªÊØ´ÒÏ ÊÂÒÁºÃÁÃÒª¡ØÁÒÃÕ ©ºÑºá¡Œä¢ ¾.È. 2551

Nutrition Website

48 àÇçºä«μÊÁÒ¤ÁâÀª¹Ò¡ÒÃáË‹§»ÃÐà·Èä·ÂÏ

www.nutritionthailand.or.th

Nutrition Activity

50 ¤Óá¹Ð¹ÓÊÓËÃѺ¼ÙŒà¢Õ¹§Ò¹ÇԨѠ51 ẺÊͺ¶ÒÁ 52 ãºÊÁѤÃÊÁÒªÔ¡ÊÁÒ¤ÁâÀª¹Ò¡ÒÃáË‹§»ÃÐà·Èä·ÂÏ

¢ŒÍà¢Õ¹áÅÐÃÙ»ÀÒ¾ μÅÍ´¨¹ÁØÁÁͧ¢Í§¼ÙŒÃ‹ÇÁàʹͺ·¤ÇÒÁã¹ÇÒÃÊÒùÕé ໚¹¤ÇÒÁ¤Ô´àËç¹Ê‹Ç¹ºØ¤¤Å ʧǹÅÔ¢ÊÔ·¸ÔìμÒÁ¡®ËÁÒ ˌÒÁ¹Óä»à¼Âá¾Ã‹«éÓ äÁ‹Ç‹ÒºÒ§Ê‹Ç¹ËÃ×Í·Ñé§ËÁ´ àÇŒ¹áμ‹ä´ŒÃѺ¤ÇÒÁÂÔ¹ÂÍÁ໚¹ÅÒÂÅѡɳÍÑ¡Éèҡ¼ÙŒ¨Ñ´·ÓÇÒÃÊÒÃà·‹Ò¹Ñé¹ Disclaimer

¢ŒÍ¤ÇÒÁâ¦É³Òã´æ ·Õè»ÃÒ¡¯ã¹ÇÒÃÊÒÃâÀª¹Ò¡ÒÃ໚¹ä»μÒÁà§×è͹䢷ҧ¸ØáԨ ¤³ÐºÃóҸԡÒÃáÅÐÊÁÒ¤ÁâÀª¹Ò¡ÒÃáË‹§»ÃÐà·Èä·Â ã¹¾ÃÐÃÒªÙ»¶ÑÁÀÊÁà´ç¨¾ÃÐà·¾ÃÑμ¹ÃÒªÊØ´ÒÏ ÊÂÒÁºÃÁÃÒª¡ØÁÒÃÕ ÁÔä´ŒàËç¹´ŒÇÂàÊÁÍä» ¼ÙŒÍ‹Ò¹¤ÇÃ㪌ÇÔ¨ÒóÞÒ³μ‹Í¢ŒÍ¤ÇÒÁâ¦É³Ò Nutrition_p2_pro1.indd Sec1:2

6/19/09 11:29:49 AM


R1_Nutrition_p3_pro1.ai

C

M

Y

CM

MY

CY

CMY

K

6/22/09

9:24:39 PM


Nutrition Letter

∫√√≥“∏‘°“√·∂≈ß Nutrition - focused journal

Ç

ÒÃÊÒÃâÀª¹Ò¡ÒéºÑ º ¹Õé ໚ ¹ ©ºÑ º ÊØ ´ ·Œ Ò Â¢Í§ »‚ ¾.È. 2551 ã¹»‚˹ŒÒÃٻẺ˹ѧÊ×ͨÐà»ÅÕè¹ â©Á˹ŒÒãˌ໚¹ÇÒÃÊÒ÷ҧÇÔªÒ¡ÒÃÁÒ¡¢Öé¹ ©ºÑº¹Õé ÁÕ ¢Œ Í Á٠Šᨌ § ¡ÒÃà»ÅÕè  ¹á»Å§ãËŒ Ê ÁÒªÔ ¡ ·ÃÒºËÅÒÂàÃ×è Í § μÑé§áμ‹àÃ×èͧ¡ÒÃÊÁѤÃÊÁÒªÔ¡ÊÁÒ¤ÁÏ ·ÕèμÑé§áμ‹»‚ 2552 ໚¹μŒ¹ä» ¨ÐÁÕáμ‹ÊÁÒªÔ¡ÊÒÁÑÞáÅÐÊÁÒªÔ¡·ÑèÇä»áºº ÃÒ»‚à·‹Ò¹Ñé¹ äÁ‹ÁÕÊÁÒªÔ¡·Ñé§ 2 »ÃÐàÀ·áººμÅÍ´ªÕ¾ ÍÕ¡μ‹Íä» ·‹Ò¹·ÕèμŒÍ§¡ÒÃÊÁѤÃÊÁÒªÔ¡ÊÁÒ¤ÁÏ ÊÒÁÒö ´ÒǹâËÅ´ãºÊÁѤÃä´Œ¨Ò¡àÇ»ä«μ¢Í§ÊÁÒ¤ÁÏ «Ö觻˜¨¨ØºÑ¹ ÊÁÒ¤ÁÏ ÁÕ¡ÒûÃѺ»ÃاàÇ»ä«μãËŒ·Ñ¹ÊÁÑÂáÅÐ໚¹Ê×èÍ¡ÅÒ§ ãËŒ¡ÑºÊÁÒªÔ¡ÁÒ¡¢Öé¹ ·Ñé§ÊÁÒªÔ¡à¡‹ÒáÅÐãËÁ‹ ÊÒÁÒö ࢌ Ò Í‹ Ò ¹áÅдÒǹ â ËÅ´ÇÒÃÊÒÃâÀª¹Ò¡ÒÃä´Œ ·Õè www.nutritionthailand.or.th â»Ã´Í‹ÒÅ×Á¢Í password áÅÐ user name ¡‹Í¹ãªŒ§Ò¹ ·‹Ò¹ÊÒÁÒö´ÙÃÒÂÅÐàÍÕ´ ¢Ñé¹μ͹μ‹Ò§æ 䴌㹷ŒÒÂàÅ‹Á¹Õé ÇÒÃÊÒéºÑ º ¹Õé ¹ Óàʹͺ·ÊÑ Á ÀÒɳ ºØ ¤ ¤ÅÊÓ¤Ñ Þ ÍÕ ¡ ºØ¤¤Å˹Öè§ã¹Ç§¡ÒÃÍÒËÒÃáÅÐâÀª¹Ò¡Òâͧ»ÃÐà·Èä·Â ...ÈÒÊμÃÒ¨ÒÏ ´Ã.ÊÔ ÃÔ ¹ ·Ã ¾Ô ºÙ Å ¹Ô  Á... Í´Õ μ ¼ÙŒ Í Ó¹Ç¡ÒÃÊ¶ÒºÑ ¹ ÇÔ ¨Ñ  áÅÐ¾Ñ ² ¹ÒÇÔ · ÂÒÈÒÊμÏ á ÅÐ à·¤â¹âÅÂÕ ÁËÒÇÔ·ÂÒÅÑÂÁËÔ´Å ¼ÙŒ¡‹ÍμÑé§áÅÐÍ´Õμ¼ÙŒÍӹǡÒà ¤¹áá¢Í§ÇÔ · ÂÒÅÑ Â ¹Ò¹ÒªÒμÔ ÁËÒÇÔ · ÂÒÅÑ Â ÁËÔ ´ Å »˜ ¨ ¨Ø ºÑ ¹ ·‹ Ò ¹à»š ¹ ·Õè » ÃÖ ¡ ÉҢͧÊÁÒ¤ÁâÀª¹Ò¡ÒÃáË‹ § 4

»ÃÐà·Èä·ÂÏ ·‹Ò¹¨ÐÁÒ¶‹Ò·ʹ»ÃÐʺ¡Òó·Õè໚¹¡ÒúÙóÒÈÒÊμÏ ·Ò§ÇÔ·ÂÒÈÒÊμÏ ÍÒËÒà âÀª¹Ò¡Òà áÅÐÊØ¢ÀÒ¾ 㹡ÒþѲ¹Òǧ¡Òà âÀª¹Ò¡Òâͧä·Â «Ö觨Ð໚¹»ÃÐ⪹á¡‹¹Ñ¡âÀª¹Ò¡ÒÃÃØ‹¹»˜¨¨ØºÑ¹áÅÐ Í¹Ò¤μ ¹Í¡¨Ò¡¹Õé ã ¹»‚ Ë ¹Œ Ò ÃÐËÇ‹ Ò §ÇÑ ¹ ·Õè 4-9 μØ Å Ò¤Á 2552 ÊÁÒ¤Á âÀª¹Ò¡ÒÃÏ ä´ŒÃѺà¡ÕÂÃμÔãˌ໚¹à¨ŒÒÀÒ¾¨Ñ´§Ò¹»ÃЪØÁÇÔªÒ¡ÒÃâÀª¹Ò¡Òà ¹Ò¹ÒªÒμÔ¤ÃÑ駷Õè 19 (19th ICN 2009) «Öè§à»š¹¤ÃÑé§áá·Õè»ÃÐà·Èä·Âä´Œ ໚¹à¨ŒÒÀҾ㹡ÒèѴ§Ò¹¹Õé áÅÐ໚¹âÍ¡ÒÊÍѹ´Õ¢Í§ÊÁҪԡ㹡ÒûÃЪØÁ ÇÔªÒ¡ÒÃáÅйÓàʹͼŧҹÃдѺ¹Ò¹ÒªÒμÔã¹»ÃÐà·Èä·Â ·Ò§ÇÒÃÊÒà 䴌ÊÑÁÀÒɳ ÃͧÈÒÊμèÒÏ ´Ã.àÍÁÍà ÇÊѹÇÔÊØ·¸Ôì à¾×èÍãËŒ¢ŒÍÁÙÅã¹ àÃ×èͧ´Ñ§¡Å‹ÒÇ »˜¨¨ØºÑ¹ Nutrigenomics ໚¹·Õèμ×è¹μÑÇã¹ÃдѺÊÒ¡Å áμ‹Âѧ¤§à»š¹ àÃ×èͧãËÁ‹ÊÓËÃѺ¹Ñ¡âÀª¹Ò¡ÒÃä·Â ·Ò§ÇÒÃÊÒè֧¹Óàʹͺ·¤ÇÒÁÇÔªÒ ¡ÒÃàÃ×è Í § “¡ÒáÅÒÂ¾Ñ ¹ ¸Ø ¢ ͧÂÕ ¹ àÅ»·Ô ¹ ¡Ñ º ¡ÒÃà¡Ô ´âä͌ Ç ¹” áÅÐ Melanocortin-4 receptor ¡Ñºâä͌ǹ” à¾×èÍãËŒ¢ŒÍÁÙÅã¹àªÔ§ÅÖ¡ á¡‹¹Ñ¡ ÇÔªÒ¡ÒôŒÒ¹ÍÒËÒÃáÅÐâÀª¹Ò¡Òà ʋǹ§Ò¹ÇÔ¨ÑÂ㹩ºÑº¹Õé ¹ÓàÊ¹Í 2 àÃ×è Í § àÃ×è Í §áá໚ ¹ §Ò¹ÇÔ ¨Ñ  à¡Õè Â Ç¡Ñ º ÊÒÃÍÒËÒà 䴌 á ¡‹ à¡Å× Í áË â¾ÅÕ ¿‚ ¹ ÍÅ á·¹¹Ô ¹ áÅÐä¿àμ· ã¹¼ÅäÁŒ ä ·Â·Õè ¹Ô Â ÁºÃÔ â À¤·Ñè Çä» ¢ŒÍÁÙÅàËÅ‹Ò¹Õé໚¹»ÃÐ⪹·Ñ駤¹»¡μÔáÅмٌ»†Ç·ÕèμŒÍ§¤Çº¤ØÁ¡ÒúÃÔâÀ¤ à¡Å×Íá˺ҧª¹Ô´ ઋ¹ â»áμÊà«ÕÂÁ áÅÐâ«à´ÕÂÁ ໚¹μŒ¹ ʋǹàÃ×èͧ ·ÕèÊͧ ໚¹¡ÒûÃÐàÁÔ¹¤ÇÒÁàÊÕ觡ÒÃä´ŒÃѺÊÑÁ¼ÑÊÊÕÊѧà¤ÃÒÐˏ¼ÊÁÍÒËÒà 㹼ÅÔμÀѳ±ÍÒËÒ÷Õèà´ç¡¹Ñ¡àÃÕ¹ã¹à¢μàÁ×ͧáÅÐà¢μª¹º·¹ÔÂÁºÃÔâÀ¤ ·‹Ò¹¤Ô´Ç‹Òà´ç¡¹Ñ¡àÃÕ¹ã¹à¢μã´ÁÕ¤ÇÒÁàÊÕ觡ѹ ·Œ Ò ÂÊØ ´ ·Ò§ÇÒÃÊÒÃÏ ã¤Ã‹ ¢ ÍàªÔ Þ ªÇ¹ãËŒ ·‹ Ò ¹ÊÁÒªÔ ¡ ·Ø ¡ ·‹ Ò ¹ ¤³Ò¨ÒÏ áÅйѡÈÖ¡ÉÒÃдѺºÑ³±Ôμã¹Ê¶ÒºÑ¹μ‹Ò§æ ·ÑèÇ»ÃÐà·ÈÊ‹§º· ÇÔ¨ÑÂáÅк·¤ÇÒÁÇÔªÒ¡ÒûÃÐàÀ· nutrition review ࢌÒÁÒà¾×è;ԨÒÃ³Ò Å§μÕ¾ÔÁ¾ ©ºÑºË¹ŒÒ໚¹μŒ¹ä» ·Ò§ÇÒÃÊÒÃÏ ¨ÐãËŒ¾×é¹·Õè¡Ñºº·¤ÇÒÁÇԨѠÁÒ¡¢Öé¹ áÅÐÍ‹ÒÅ×ÁÊ‹§¼Å§Ò¹ÇÔªÒ¡ÒùÓàʹÍ㹧ҹ The 19th ICN 2009 ÀÒÂã¹à´×͹àÁÉÒ¹ 2552 áÅÐŧ·ÐàºÕ¹¡ÒûÃЪØÁã¹ÃÒ¤Ò ¾ÔàÈÉ¡‹Í¹Çѹ·Õè 3 ÊÔ§ËÒ¤Á 2552 (´ÙÃÒÂÅÐàÍÕ´»¡ËÅѧ) ¾º¡Ñ¹©ºÑºË¹ŒÒ¤‹Ð ·Ô¾Âà¹μà ºÃóҸԡÒÃ

«“√ “√‚¿™π“°“√

Nutrition_p4_pro1.indd Sec1:4

6/18/09 10:08:46 PM


Nutrition

Icon

ÊÑÁÀÒɳáÅÐàÃÕºàÃÕ§â´Â ÊؾԪÞÒ ÈÃÕÀÁà sr.supichaya@foodfocusthailand.com

‡√◊ Õ Ë ß‡≈à “ ¢Õß‚¿™π“°√... ∫π‡ âπ∑“ß°“√æ—≤π“‡æ◊ËÕ‚¿™π“°“√∑’Ë¥’ »“ μ√“®“√¬å‡°’¬√쑧ÿ≥ ¥√. ‘√‘π∑√å æ‘∫Ÿ≈π‘¬¡ ∑’˪√÷°…“ ¡“§¡‚¿™π“°“√·Ààߪ√–‡∑»‰∑¬„πæ√–∫√¡√“™Ÿª∂—¡¿å¢Õß ¡‡¥Á®æ√–‡∑æ√—μπ√“™ ÿ¥“œ  ¬“¡∫√¡√“™°ÿ¡“√’

ÍÒËÒ÷ÕèàÃÒÃѺ»Ãзҹ¡Ñ¹ÍÂÙ‹·Ø¡Çѹ¹Õé ¤§à»š¹·Õè¤ØŒ¹à¤Â¢Í§ ¼ÙŒºÃÔâÀ¤à»š¹Ê‹Ç¹ãËÞ‹ áμ‹ËÒ¡¡ÅѺ仾ԨÒóÒÍÒËÒÃàÁ×èͤÃÑé§Í´Õμ ·Õè ¤ ¹ä·Â¹Ô  ÁºÃÔ â À¤ ¨Ð¾ºÇ‹ Ò ª‹ Ò §áμ¡μ‹ Ò §¡Ñ ¹ àÊÕ Â àËÅ× Í à¡Ô ¹ ¹Í¡¨Ò¡¤ÇÒÁáμ¡μ‹Ò§´ŒÒ¹ÃʪÒμÔáÅÐͧ¤»ÃСͺáÅŒÇ ÊÔ觷Õè à»ÅÕè  ¹á»Å§ä»ã¹·Ò§âÀª¹ÈÒÊμÏ ¡ç à »š ¹ ÍÕ ¡ »ÃСÒÃ˹Öè § ·Õè ¹Ñ¡âÀª¹Ò¡ÒäÇÃμÃÐ˹ѡ¶Ö§ ÇÒÃÊÒÃâÀª¹Ò¡ÒÃÏ àÅ‹Á¹Õé ä´Œ R1_Nutrition_p5-9_pro1.indd Sec1:5

ÃѺà¡ÕÂÃμÔ¨Ò¡ÈÒÊμÃÒ¨ÒÏà¡ÕÂÃμԤس ´Ã.ÊÔÃÔ¹·Ã ¾ÔºÙŹÔÂÁ ·Õè»ÃÖ¡ÉÒÊÁÒ¤ÁâÀª¹Ò¡ÒÃáË‹§»ÃÐà·Èä·Âã¹¾ÃкÃÁÃÒªÙ»¶ÑÁÀ ¢Í§ÊÁà´ç¨¾ÃÐà·¾ÃÑμ¹ÃÒªÊØ´Ò Ï ÊÂÒÁºÃÁÃÒª¡ØÁÒÃÕ ÁÒ ¶‹ Ò Â·Í´àÃ×è Í §ÃÒǺ¹àÊŒ ¹ ·Ò§âÀª¹ÈÒÊμÏ ã ËŒ à ÃÒä´Œ μ ÃÐË¹Ñ ¡ áÅоÌÍÁÃѺÁ×͡Ѻ»˜ÞËÒ´ŒÒ¹âÀª¹Ò¡ÒÃ䴌͋ҧ·Ñ¹·‹Ç§·Õ ªï∑’Ë 43 ©∫—∫∑’Ë 4 μÿ≈“§¡ - ∏—𫓧¡ 2551

5

6/22/09 9:42:11 PM


®ÿ¥‡√‘Ë¡μâπ∫π‡ âπ∑“ß«ß°“√Õ“À“√·≈–‚¿™π“°“√

ËÅѧ¨Ò¡·ÕèÈÒÊμÃÒ¨ÒÏà¡ÕÂÃμԤس ´Ã.ÊÔÃÔ¹·Ã ¾ÔºÙŹÔÂÁ ¨º´Øɮպѳ±Ôμ´ŒÒ¹ªÕÇà¤ÁÕáÅÐâÀª¹Ò¡Òà ¨Ò¡ÁËÒÇÔ·ÂÒÅÑÂÎÒÏÇÒÏ´ »ÃÐà·ÈÊËÃÑ°ÍàÁÃÔ¡Ò ·‹Ò¹ä´Œ¡ÅѺÁÒ໚¹ÍÒ¨ÒÏ»ÃШӷÕèÀÒ¤ÇÔªÒà¤ÁÕ ÁËÒÇÔ·ÂÒÅÑÂà¡ÉμÃÈÒÊμÏ ໚¹ÃÐÂÐàÇÅÒ 3 »‚ áÅÐä´ŒÃÔàÃÔèÁ¡‹ÍμÑé§ÀÒ¤ÇÔªÒÇÔ·ÂÒÈÒÊμÏáÅÐà·¤â¹âÅÂÕ ¡ÒÃÍÒËÒâÖé¹ ¨Ò¡¹Ñé¹ä´ŒÂŒÒÂä»ÃѺÃÒª¡Ò÷Õ褳ÐÇÔ·ÂÒÈÒÊμÏ ÁËÒÇÔ·ÂÒÅÑÂÁËÔ´Å àÁ×èÍàÃÔèÁ¡‹ÍμÑé§ ÀÒ¤ÇÔªÒªÕÇà¤ÁÕ «Ö觹Ѻ໚¹ËÑÇ˹ŒÒÀÒ¤ÇÔªÒ¤¹ä·Â¤¹áá (¡‹Í¹Ë¹ŒÒ¹Ñé¹à»š¹ªÒÇμ‹Ò§»ÃÐà·È) ã¹ ÃÐËÇ‹Ò§´ÓçμÓá˹‹§ÍÒ¨ÒÏ䴌Ê͹ÇÔªÒªÕÇà¤ÁÕãËŒ¡Ñº¹Ñ¡ÈÖ¡ÉÒ¤³Ðá¾·ÂÈÒÊμÏ âç¾ÂÒºÒÅÃÒÁÒ¸Ôº´Õ áÅÐÊ͹ÇÔªÒªÕÇà¤ÁÕáÅÐâÀª¹Ò¡ÒÃãËŒ¡Ñº¹Ñ¡ÈÖ¡ÉÒÃдѺ»ÃÔÞÞÒâ·áÅÐàÍ¡ ÁËÒÇÔ·ÂÒÅÑÂÁËÔ´Å ß“π«‘®—¬π”‰ª Ÿà°“√æ—≤π“

ã¹ÃÐËÇ‹Ò§´ÓçμÓá˹‹§ ÈÒÊμÃÒ¨ÒÏà¡ÕÂÃμԤس ´Ã.ÊÔÃÔ¹·Ã ¾ÔºÙŹÔÂÁ ä´Œ·Ó§Ò¹ÇԨѷҧ´ŒÒ¹âÀª¹Ò¡Òà áÅЪÕÇà¤ÁÕËÅÒÂàÃ×èͧ ઋ¹ ÇÔμÒÁÔ¹ÍÕ áÅк·ºÒ·¢Í§ÇÔμÒÁÔ¹ÍÕã¹Ã‹Ò§¡Ò ¡ÒÃà¡Ô´âäà˹纪Òà¹×èͧ¨Ò¡¢Ò´ ÇÔμÒÁÔ¹ºÕ 1 â´Â¾ºÇ‹Ò¼ÙŒ·Õè»ÃÐʺ»˜ÞËÒ¡ÒâҴÇÔμÒÁÔ¹ºÕ 1 ¹Ñé¹ Ê‹Ç¹ãËދ໚¹»ÃЪҡÃã¹à¢μÀÒ¤à˹×Í áÅÐμÐÇѹÍÍ¡à©Õ§à˹×Í ¨Ö§ä´ŒÊÓÃǨ¾ÄμÔ¡ÃÃÁ¡ÒúÃÔâÀ¤ÍÒËÒÃáÅоºÇ‹Ò»ÃЪҡÃʋǹãËÞ‹ã¹ ÀÒ¤μÐÇѹÍÍ¡à©Õ§à˹×͹ÔÂÁºÃÔâÀ¤»ÅÒÌҴԺ ã¹¢³Ð·Õè»ÃЪҡèӹǹäÁ‹¹ŒÍÂã¹à¢μÀÒ¤à˹×͹ÔÂÁ ºÃÔâÀ¤ãºªÒËÃ×ÍãºàÁÕè§ËÇÁ¡ÑºÍÒËÒà ¨Ö§ä´Œ·Ó¡Ò÷´Êͺâ´Â¡ÒùӻÅÒÃŒÒ ãºªÒáÅÐãºàÁÕèÂ§ä» ·Ó¡ÒÃÇÔà¤ÃÒÐˏ ¨Ò¡¡ÒÃÇÔà¤ÃÒÐˏ¾ºÇ‹Ò ã¹»ÅÒÌһÃСͺ仴ŒÇÂÊÒÃÍÒËÒÃËÅÒª¹Ô´ áμ‹ÁÕà͹ä«Á ª¹Ô´Ë¹Ö觷ÕèÁռŷÓÅÒÂÇÔμÒÁÔ¹ºÕ 1 ·ÓãˌËҧ¡ÒÂäÁ‹ÊÒÁÒö¹Óä»ãªŒä´Œ à͹ä«Á´Ñ§¡Å‹ÒǤ×Íà͹ä«Áä¸ÍÐÁÔà¹Ê ʋǹ¼Å¨Ò¡¡ÒÃÇÔà¤ÃÒÐˏ㺪ÒáÅÐãºàÁÕ觹Ñé¹ ¾ºÇ‹ÒÁÕʋǹ»ÃСͺ¢Í§ÊÒê¹Ô´â¾ÅÔ¿‚¹ÍŠઋ¹ á·¹¹Ô¹ «Öè§ÊÒÁÒö¨Ñº¡ÑºÇÔμÒÁÔ¹ºÕ 1 ã¹ÍÒËÒà ·ÓãËŒ¼ÙŒ·Õè´×èÁ¹éÓªÒËÃ×Íà¤ÕéÂÇãºªÒ ãºàÁÕè§ËÅѧÍÒËÒà ËÃ×ÍËÇÁ¡ÑºÍÒËÒÃ໚¹»ÃШӹÑé¹ ÍÒ¨¢Ò´ÇÔμÒÁÔ¹ºÕ 1 àÁ×è;º»˜ÞËÒઋ¹¹Ñé¹áÅŒÇ ¨Ö§ä´Œ·Ó¡ÒÃÇÔà¤ÃÒÐˏÇÔ¸Õ à´ÕÂǡѹ â´Âà»ÅÕè¹ãËŒ¡ÅØ‹Á·´ÅͧºÃÔâÀ¤»ÅÒÃŒÒμŒÁÊØ¡á·¹áÅÐãËŒºÃÔâÀ¤ãºªÒËÃ×ÍãºàÁÕè§ËÅѧ¨Ò¡ ÃѺ»ÃзҹÍÒËÒÃä»áÅŒÇÍ‹ҧμèÓ 30 ¹Ò·Õ «Ö觨ҡ¡Ò÷´Åͧ´Ñ§¡Å‹ÒÇä´Œ¼Å໚¹·Õ蹋ҾÍ㨠¤×Í ¡ÅØ‹Á·´ÅͧÁÕÍÒ¡ÒÃà˹纪ÒÅ´¹ŒÍÂŧËÃ×ÍËÁ´ä» ʋǹÍÕ¡¡Ò÷´Åͧ˹Ö觹Ñé¹ä´Œ·´Êͺâ´Â¡Òúպ ¹éÓÁйÒÇËÃ×ÍàμÔÁÇÔμÒÁÔ¹«Õŧä»ã¹¹éÓªÒ «Ö觾ºÇ‹ÒÊÒÁÒöÂѺÂÑ駡Ò÷ÓÅÒÂÇÔμÒÁÔ¹ºÕ 1 ä´Œ ¹Í¡¨Ò¡¹ÕéÂѧÁÕ§Ò¹ÇÔ¨ÑÂàÃ×èͧ¤ÇÒÁ´×éͧ͢àª×éÍÁÒàÅàÃÕÂã¹àÅ×Í´¢Í§¼ÙŒ»†ÇÂáÅмٌ·ÕèÁÕÊÀҾËҧ¡Ò»¡μÔ â´ÂÈÖ¡ÉÒËÇÁ¡Ñº¤³Ð·Ó§Ò¹à¾×èÍÃÔàÃÔèÁãËŒÁÕ¡ÒäØÁ¡Óà¹Ô´ã¹à¾ÈªÒ áÅÐÅ´ÍÑμÃÒ¡ÒÃà¡Ô´âäÁÐàÃç§àμŒÒ¹Á áÅÐÁÐàÃ移ҡÁ´ÅÙ¡¨Ò¡¡ÒÃ㪌ÂÒ¤ØÁ¡Óà¹Ô´ã¹à¾ÈËÞÔ§ ÍÒ¨ÒϷӧҹ䴌ÃÐÂÐ˹Ö觷‹Ò¹¡çÂŒÒÂä»´Óç μÓá˹‹§¼ÙŒÍӹǡÒÃÇÔ·ÂÒà¢μÈÒÅÒÂÒ ÁËÒÇÔ·ÂÒÅÑÂÁËÔ´Å ã¹»‚ ¾.È. 2523 à¾×èÍàμÃÕÂÁ¤ÇÒÁ¾ÃŒÍÁ ´ŒÒ¹ÍÒ¤ÒÃʶҹ·Õè Ë;ѡÍÒÈÑ¢ͧ¹Ñ¡ÈÖ¡ÉÒ áÅÐÊÔè§ÍӹǤÇÒÁÊдǡμ‹Ò§ æ ÊÓËÃѺ¡ÒÃŒҹѡÈÖ¡ÉÒ ªÑé¹»‚·Õè 1 ä»ÂѧÇÔ·ÂÒà¢μÈÒÅÒÂÒ ã¹»‚ ¾.È. 2525 áÅÐä´Œ¶‹ÒÂâ͹§Ò¹ÇÔ¨ÑÂãËŒ¡Ñº¼ÙŒÃ‹ÇÁÇԨѷ‹Ò¹Í×è¹à¾×èÍ ´Óà¹Ô¹¡ÒÃμ‹Íä» μ‹ÍÁÒÈÒÊμÃÒ¨ÒÏà¡ÕÂÃμԤس ´Ã.ÊÔÃÔ¹·Ã ¾ÔºÙŹÔÂÁ ä´Œ´ÓçμÓá˹‹§¼ÙŒÍӹǡÒÃʶҺѹÇԨѠÇÔ·ÂÒÈÒÊμÏáÅÐà·¤â¹âÅÂÕ â´Âä´ŒºØ¡àºÔ¡ãËŒÁÕÊÒ¢ÒÇԨѷÕèËÅÒ¡ËÅÒ¢Öé¹ ÁըشÁØ‹§ËÁÒÂà¾×èÍãËŒÁÕ¡ÒùÓÇÔªÒ ÇÔ·ÂÒÈÒÊμÏä»ãªŒã¹¡ÒÃá¡Œ»˜ÞËҢͧªØÁª¹ ÀÒÂãμŒËÅÑ¡¡Òà “from Molecule to Community” ¹Ñ蹤×Í ¡ÒùÓàÍÒ§Ò¹ÇÔ¨ÑÂÃдѺâÁàÅ¡ØÅ仾Ѳ¹ÒÍ‹ҧμ‹Íà¹×èͧ¨¹¡ÃзÑè§ÊÒÁÒö»ÃÐÂØ¡μãªŒà¾×èÍ á¡Œ»˜ÞËÒªØÁª¹ä´Œ â´Âã¹Ê¶ÒºÑ¹ Ï »ÃСͺ仴ŒÇ¤³Ò¨ÒϼٌàªÕèÂǪÒÞã¹ÊÒ¢ÒÇÔ¨ÑÂμ‹Ò§ æ â´Â ·‹Ò¹´ÓçμÓá˹‹§¨¹¡ÃзÑè§à¡ÉÕ¹ÍÒÂØÃÒª¡Òà ¹Ñºà»š¹ÃÐÂÐàÇÅÒ 8 »‚ ã¹àÇÅÒà´ÕÂǡѹ·‹Ò¹Âѧ䴌໚¹ ¼ÙŒ¡‹ÍμÑé§ÇÔ·ÂÒÅѹҹҪÒμÔ ÁËÒÇÔ·ÂÒÅÑÂÁËÔ´Å «Öè§ÁÕ¡ÒÃàÃÕ¹¡ÒÃÊ͹໚¹ÀÒÉÒÍѧ¡ÄÉ·Ñé§ËÁ´ â´ÂàÃÔèÁ ´Óà¹Ô¹¡ÒÃÀÒÂãμŒËÅÑ¡ÊÙμÃμÒÁÁÒμðҹÊÒ¡Å ¹Ñ蹤×Í ã¹ª‹Ç§ 2 »‚áá ໚¹ËÅÑ¡ÊÙμþ×é¹°Ò¹·Ñ駴ŒÒ¹ ÇÔ·ÂÒÈÒÊμÏ Êѧ¤ÁÈÒÊμÏáÅÐÈÔÅ»ÈÒÊμÏ à¾×èÍãËŒ¹Ñ¡ÈÖ¡ÉÒÁÕ¾×鹰ҹ෋Òà·ÕÂÁ¡Ñº¹Ñ¡ÈÖ¡ÉÒ¹Ò¹ÒªÒμÔ áÅÐ 6

««““√√  “√ «“√ “√‚¿™π“°“√ “√‚¿ ‚¿™π ™π“° “°““√√

R1_Nutrition_p5-9_pro1.indd Sec1:6

6/22/09 9:42:12 PM


»Ù¾×é¹°Ò¹ãËŒ¹Ñ¡ÈÖ¡ÉÒÁÕ¤ÇÒÁÃͺÃÙŒáÅÐÇÔÊÑ·Ñȹ¡ÇŒÒ§¢ÇÒ§ã¹ÃдѺ ÊÒ¡Å ËÃ×Í·ÕèàÃÕ¡NjҡÒÃÊÌҧ¤¹ãˌ໚¹ Global Population ¨Ò¡¹Ñ鹨֧á¡Í͡໚¹ÊÒ¢Òμ‹Ò§ æ 㹪‹Ç§Êͧ»‚ËÅѧ ¹Í¡¨Ò¡¹ÕéÍÒ¨ÒÏÂѧ໚¹¼ÙŒàÃÔèÁ¡‹ÍμÑé§ÊÒ¢ÒºÃÔËÒà âçáÃÁ áÅСÒ÷‹Í§à·ÕèÂÇ (Travel industry management) à¹×èͧ¨Ò¡ àÅç§àËç¹Ç‹Ò¼ÙŒºÃÔËÒÃáÅмٌ»¯ÔºÑμÔ§Ò¹ÃдѺ¡ÅÒ§ã¹ÊҢҴѧ¡Å‹ÒÇ ¤‹Í¹¢ŒÒ§¹ŒÍÂáÅТҴá¤Å¹ â´Âä´Œ¢Í¤Ó»ÃÖ¡ÉÒ¨Ò¡·‹Ò¹¼ÙŒËÞÔ§ ª¹Ñ춏 »ÂÐÍØ ਌ҢͧâçáÃÁ´ØÊÔμ¸Ò¹Õ ¾ºÇ‹ÒºØ¤ÅҡúÃÔËÒà ÃдѺ¡ÅÒ§ (Middle manager) Âѧ¢Ò´ÍÂÙ‹ ´Ñ§¹Ñ鹨֧μŒÍ§ÊÌҧ ºØ¤Åҡôѧ¡Å‹ÒÇà¾×è;Ѳ¹Ò໚¹¼ÙŒºÃÔËÒÃÃдѺÊÙ§μ‹Íä» â´Â¨Ñ´ ãËŒÁÕ¡ÒÃàÃÕ¹¡ÒÃÊ͹ÀÒÉÒ¨Õ¹áÅÐÞÕè»Ø†¹à¾ÔèÁàμÔÁ´ŒÇÂáÅШҡ ¡ÒÃàÅç§àËç¹»˜ÞËÒμ‹Ò§ æ ¨Ö§ÁÕá¹Ç¤Ô´Ç‹Ò¡ÒþѲ¹ÒμŒÍ§àÃÔèÁ¨Ò¡ ¡ÒÃ¾Ñ ² ¹Ò·Õè μÑ Ç ºØ ¤ ¤Å ¨Ö § ä´Œ ¨Ñ ´ μÑé § “ ¡Í§·Ø ¹ à¾×è Í §Ò¹ÇÔ ¨Ñ  ÈÒÊμÃÒ¨ÒÏ ´Ã.ÊÔÃÔ¹·Ã ¾ÔºÙŹÔÂÁ” ãËŒ¡Ñº¹Ñ¡ÇÔ¨ÑÂÍÕ¡´ŒÇ ªí≠À“¥â“π‚¿™π“°“√„πÕ¥’μ·≈–ªí®®ÿ∫—π

»˜ÞËÒ´ŒÒ¹âÀª¹Ò¡Òâͧ»ÃÐà·Èä·Âã¹Í´Õμ¹Ñé¹ ÍÒ¨ÒÏ䴌 ·Ó¡ÒÃÇÔ¨ÑÂËÇÁ¡Ñº ÈÒÊμÃÒ¨ÒÏà¡ÕÂÃμԤس ¹¾.ÍÒÃÕ ÇÑÅÂàÊÃÕ áÅФ³Ð ¾ºÇ‹Ò»ÃЪҡÃã¹»ÃÐà·Èä·ÂʋǹãËÞ‹»ÃÐʺ»˜ÞËÒ ¢Ò´ÊÒÃÍÒËÒà ઋ¹ ÇÔμÒÁÔ¹ºÕ 1 áÅÐ㹼ѡËÅÒª¹Ô´ÁÕÊÒ÷ÕèÁÕ Ä·¸Ôì·ÓÅÒÂÇÔμÒÁÔ¹ºÕ 1 ໚¹Ê‹Ç¹»ÃСͺÍÂÙ‹´ŒÇ ÃÇÁ件֧㹠»ÅÒÃŒÒ ãºªÒ áÅÐãºàÁÕè§ ´Ñ§àª‹¹ã¹¡Ò÷´Åͧ·Õèä´Œ¡Å‹ÒÇ ¢ŒÒ§μŒ¹ ÍÕ¡·Ñ駨ҡ¡ÒÃÇÔ¨ÑÂÂѧ䴌¾ºÇ‹Òà´ç¡Ê‹Ç¹ãËÞ‹»ÃÐʺ»˜ÞËÒ ¡ÒâҴ¾Åѧ§Ò¹áÅÐâ»ÃμÕ¹ (Protein energy malnutrition) ÃÇÁ件֧¡ÒâҴÇÔμÒÁÔ¹ÍÕ´ŒÇ àÁ×èÍÁÕ¢ŒÍÁÙŴѧ¡Å‹ÒÇáŌǨ֧䴌ÁÕ ¤ÇÒÁËÇÁÁ×͡ѹÍ‹ҧã¡ÅŒªÔ´ÃÐËÇ‹Ò§½†ÒÂÇÔ·ÂÒÈÒÊμÏ ½†Ò âÀª¹Ò¡Òà ½†Ò¾Ѳ¹Ò¼ÅÔμÀѳ±ÍÒËÒà áÅн†ÒÂÊÒ¸ÒóÊØ¢ ÁËÒÇÔ · ÂÒÅÑ Â ÁËÔ ´ Å â´Â¡ÒÃ¨Ñ ´ ·Óá¼¹¾Ñ ² ¹ÒÍÒËÒÃáÅÐ âÀª¹Ò¡ÒÃáË‹§ªÒμÔ¢Öé¹ «Öè§ÊÒÁÒöᡌ»˜ÞËÒàÃ×èͧ¡ÒâҴÊÒà ÍÒËÒÃã¹à´ç¡àÅç¡ä´ŒÍ‹ҧÁÕ»ÃÐÊÔ·¸ÔÀÒ¾áÅÐÃÇ´àÃçÇ à¹×èͧ¨Ò¡ ½† Ò Â¼ÙŒ ¼ ÅÔ μ ä´Œ ´ Óà¹Ô ¹ ¡ÒüÅÔ μãËŒ ÁÕ ¤ ÇÒÁÊÍ´¤ÅŒ Í §¡Ñ º ½† Ò Â âÀª¹Ò¡Òà ઋ¹ ¾Ñ²¹ÒÊÙμÃÍÒËÒÃà´ç¡ã¹ÀÒ¤μÐÇѹÍÍ¡à©Õ§àË¹× Í ¨Ò¡à´Ô Á ·Õè ¹Ô Â ÁãËŒ à ´ç ¡ ÃÑ º »Ãзҹ¢Œ Ò ÇÂé Ó «Öè § ໚ ¹ ¢ŒÒÇà˹ÕÂÇ·Õ輋ҹ¡ÒÃà¤ÕéÂǹÓÁÒË‹ÍãºμͧáÅлœ§ãˌÌ͹ ·ÓãËŒ à´ç ¡ ¢Ò´ÊÒÃÍÒËÒûÃÐàÀ·â»ÃμÕ ¹ ¼ÙŒ Ë Ç ÁÇÔ ¨Ñ  ¹Óâ´Â ÈÒÊμÃÒ¨ÒÏà¡ÕÂÃμԤس ¹¾.ä¡ÃÊÔ·¸Ôì μѹμÔÊÔÃÔ¹·Ã ¨Ö§ä´Œ¤Ô´¤Œ¹

ÊÙμÃÍÒËÒÃÊÓËÃѺà´ç¡·Õè»ÃСͺ仴ŒÇ¢ŒÒÇ : ¶ÑèÇ : §Ò ã¹ ÍÑμÃÒʋǹ 1 : 1 : 1 ¹Ó仺´´ŒÇ¤áãËŒÅÐàÍÕ´¡‹Í¹¨Ð¹Óä» ¡Ç¹ãËŒÊØ¡áÅÐãËŒà´ç¡ÃѺ»Ãзҹ ¾ºÇ‹ÒÊÒÁÒöᡌ»˜ÞËÒ¢Ò´ â»ÃμÕ¹áÅоÅѧ§Ò¹ã¹à´ç¡ä´Œ ½†ÒÂÁËÒÇÔ·ÂÒÅÑÂà¡ÉμÃÈÒÊμϨ֧ ä´Œ¼ÅÔμâ»ÃμÕ¹à¡ÉμâÖé¹ áÅн†ÒÂÊÒ¸ÒóÊآ໚¹¼ÙŒ¹Ó¢ŒÍÁÙÅáÅÐ ÊÙμÃÍÒËÒ÷Õè¾Ñ²¹Ò¢Öé¹ãËÁ‹ä»à¼Âá¾Ã‹ ÃÇÁ·Ñé§ÁÕ¡ÒÃཇÒÃÐÇѧ àÃ×èͧà´ç¡¢Ò´ÊÒÃÍÒËÒÃà¾×èÍãˌᡌ»˜ÞËÒä´Œ·Ñ¹·‹Ç§·Õ ¨Ò¡¡Òà ᡌ»˜ÞËÒ´ŒÒ¹âÀª¹Ò¡Òôѧ¡Å‹ÒÇ Í§¤¡ÒÃ͹ÒÁÑÂâÅ¡ (World Health Organization; WHO) ä´Œ»ÃСÒÈà¡ÕÂÃμԤسãˌᡋ »ÃÐà·Èä·Â·ÕèÊÒÁÒöᡌ»˜ÞËÒàËÅ‹Ò¹Õé䴌͋ҧÃÇ´àÃçÇ áμ‹ã¹»˜¨¨ØºÑ¹¡ÅѺ¾ºÇ‹Ò»˜ÞËÒâÀª¹Ò¡Òâͧ»ÃÐà·Èä·ÂÁÕ ·ÔÈ·Ò§μç¡Ñ¹¢ŒÒÁ¨Ò¡ã¹Í´Õμâ´ÂÊÔé¹àªÔ§ ¤×Í ¡Ç‹ÒÃŒÍÂÅÐ 20 ¢Í§ àÂÒǪ¹»ÃÐʺ»˜ÞËÒâä͌ǹ à¹×èͧ¨Ò¡ÁÕ¾ÄμÔ¡ÃÃÁ¡ÒúÃÔâÀ¤ àÅÕ¹ẺªÒÇμÐÇÑ¹μ¡ «Öè§ÍÒËÒÃàËÅ‹Ò¹Ñé¹ÅŒÇ¹ÍØ´Áä»´ŒÇÂä¢Áѹ ¤ÒÏâºäÎà´Ãμ â»ÃμÕ¹ áÅÐãËŒ¾Åѧ§Ò¹ÊÙ§ áμ‹ÁռѡËÃ×ͼÅäÁŒ¹ŒÍ äÁ‹à¾Õ§¾Íμ‹Í¤ÇÒÁμŒÍ§¡ÒâͧËҧ¡Ò ¨Ò¡¡ÒÃàÅç§àË繶֧»˜ÞËҴѧ¡Å‹ÒÇ ÇزÔÍÒÊÒ¸¹Ò¤ÒÃÊÁͧ ÊÒ¢ÒÊØ¢ÀÒ¾·Õè ÈÒÊμÃÒ¨ÒÏà¡ÕÂÃμԤس ´Ã.ÊÔÃÔ¹·Ã ¾ÔºÙŹÔÂÁ ໚¹ÊÁÒªÔ¡ÍÂÙ‹ä´ŒÃѺ·Ø¹ÇԨѨҡÊÀҾѲ¹Ò¡ÒÃàÈÃÉ°¡Ô¨áÅÐ Êѧ¤ÁáË‹§ªÒμÔ ãËŒ·Ó¡ÒÃÇÔ¨ÑÂá¡Œ»˜ÞËÒ¡ÒâҴÍÒËÒäǺ¤Ù‹ ä» ¡Ñº¡Òû‡Í§¡Ñ¹âä͌ǹ ÀÒÂãμŒª×èÍâ¤Ã§¡Òà “¾Ñ²¹Òà´ç¡ä·ÂãËŒ àμçÁÈÑ¡ÂÀÒ¾´ŒÇÂÍÒËÒÃáÅÐâÀª¹Ò¡ÒÔ â´Â·Ó¡ÒþѲ¹ÒÍÒËÒà ¡ÅÒ§Çѹ àÃÔèÁ¨Ò¡¡ÒþѲ¹ÒÍÒËÒáÅÒ§Çѹã¹âçàÃÕ¹·Ñé§ 4 ÀÙÁÔÀÒ¤¢Í§»ÃÐà·È ÃÇÁ·Ñé§âçàÃÕ¹μÓÃǨμÃÐàǹªÒÂá´¹ àÃÔèÁáμ‹ÃдѺ͹غÒÅ à¾×èÍÊÌҧÇÔÊѺÃÔâÀ¤·Õè´ÕáÅÐã¹âçàÃÕ¹ ÃдѺ»ÃжÁÈÖ¡ÉÒáÅÐÁѸÂÁÈÖ¡ÉÒ ä´ŒãËŒ¡ÒÃʹѺʹعâ¤Ã§¡Òà à¡ÉμÃà¾×èÍÍÒËÒáÅÒ§Çѹ㹪¹º· áÅÐãËŒ¤ÇÒÁÃÙŒ´ŒÒ¹âÀª¹Ò¡Òà ᡋ¤ÃÙ ¼ÙŒ»ÃСͺÍÒËÒà áÅйѡàÃÕ¹ ÁÕ¡ÒÃÊÌҧ¹Ñ¡ÇÔ¨ÑÂÃØ‹¹¨ÔëÇ â´ÂãËŒ¹Ñ¡àÃÕ¹ËÇÁ¡Ñ¹¤Œ¹ËÒ»˜ÞËÒÍÒËÒà áÅÐâÀª¹Ò¡ÒÃã¹ âçàÃÕ¹¢Í§μ¹ áÅÐËÇÁ¡Ñº¤ÃÙ·Õè»ÃÖ¡ÉÒ㹡ÒÃá¡Œ»˜ÞËÒ·Ñ駴ŒÒ¹ âÀª¹Ò¡Òà ÍÒËÒÃáÅÐÊØ¢ÒÀÔºÒÅ ÃÇÁ·Ñé§μÑ駪ÁÃÁμ‹Ò§ æ ¢Öé¹ ã¹âçàÃÕ¹ ઋ¹ ªÁÃÁ¡ÒÃÍÍ¡¡ÓÅѧ¡Ò ໚¹μŒ¹ áÅТÂÒ¼ŠÊÙ‹âçàÃÕ¹ã¡ÅŒà¤Õ§ ªï∑’Ë 43 ©∫—∫∑’Ë 4 μÿ≈“§¡ - ∏—𫓧¡ 2551

R1_Nutrition_p5-9_pro1.indd Sec1:7

7

6/22/09 9:42:13 PM


¹Í¡¨Ò¡¹ÕéÊÁÒ¤ÁâÀª¹Ò¡ÒÃáË‹§»ÃÐà·Èä·ÂÏ Ã‹ÇÁ¡Ñº¡Í§ âÀª¹Ò¡Òà ¡ÃÁ͹ÒÁÑ ¡ÃзÃǧÊÒ¸ÒóÊØ¢ ´Óà¹Ô¹¡Òà â¤Ã§¡ÒÃâÀª¹Ò¡ÒÃàªÔ§ÃØ¡ «Öè§ä´ŒÃѺ¡ÒÃʹѺʹعà§Ô¹·Ø¹ÇԨѨҡ Êӹѡ§Ò¹¡Í§·Ø¹Ê¹ÑºÊ¹Ø¹¡ÒÃÊÌҧàÊÃÔÁÊØ¢ÀÒ¾ (ÊÊÊ.) áÅÐ ·Ó¡ÒÃÇÔ¨ÑÂμ‹Íà¹×èͧâ´Â¡ÒÃÊÃØ»ÂØ·¸ÈÒÊμÏ㹡ÒþѲ¹ÒÍÒËÒà áÅÐâÀª¹Ò¡ÒÃã¹âçàÃÕ¹àÍ¡ª¹ âçàÃÕ¹à·ÈºÒÅ âçàÃÕ¹ ¢Í§¡ÃзÃǧÈÖ¡ÉÒ¸Ô¡Òà Êӹѡ§Ò¹¤³Ð¡ÃÃÁ¡ÒáÒÃÈÖ¡ÉÒ ¾×é¹°Ò¹ áÅÐâçàÃÕ¹ã¹Êѧ¡Ñ´¡Ãا෾ÁËÒ¹¤Ã ÃÇÁ·Ñ駾Ѳ¹Ò ÊÙμÃÍÒËÒÃä·Â·Õè¶Ù¡μŒÍ§μÒÁËÅÑ¡âÀª¹Ò¡Òà à¾×èÍÅ´¤ÇÒÁËÇÒ¹ Áѹ à¤çÁ ŧ «Ö觨мÅÑ¡´Ñ¹ä»ÊÙ‹¹âºÒÂÃдѺªÒμÔμ‹Íä» ¹Í¡¨Ò¡¹Õé¡ÃзÃǧÊÒ¸ÒóÊآ䴌¨Ñ´¡ÒÃó礏âä͌ǹ㹠¼ÙŒãËÞ‹ÀÒÂãμŒâ¤Ã§¡Òà “¤¹ä·ÂäÃŒ¾Ø§” ¢Öé¹ à¾×èÍÅ´»ÃÔÁÒ³ ¡Òà à¡Ô´âä͌ǹãËŒ¹ŒÍÂŧ ·Ñ駹Õéà¹×èͧ¨Ò¡âä͌ǹ໚¹âä·Õè¹Óä»ÊÙ‹¡Òà à¡Ô´âääÁ‹μÔ´μ‹ÍàÃ×éÍÃѧËÅÒª¹Ô´ ઋ¹ âäàºÒËÇÒ¹ âä¤ÇÒÁ ´Ñ¹âÅËÔμ âää¢ÁѹÍØ´μѹã¹ËÅÍ´àÅ×Í´ËÑÇã¨áÅÐÊÁͧ «Ö觡Òà ó礏´Ñ§¡Å‹ÒǹÑé¹ ä´Œá¹Ð¹ÓãËŒ¤¹ä·ÂºÃÔâÀ¤¼Ñ¡¼ÅäÁŒÁÒ¡¢Öé¹ áÅÐÅ´¡ÒúÃÔâÀ¤ÃÊËÇÒ¹ Áѹ à¤çÁ ÃÇÁ件֧ËÁÑè¹ÍÍ¡¡ÓÅѧ ¡ÒÂÍ‹ҧÊÁèÓàÊÁÍ à¾×èÍÅ´¤ÇÒÁàÊÕè§㹡ÒÃà¡Ô´âäáÅÐà»ÅÕè¹ ·Ñȹ¤μÔáÅоÄμÔ¡ÃÃÁ¡ÒúÃÔâÀ¤¢Í§¤¹ä·Âã¹ÃÐÂÐÂÒÇ °“√∫Ÿ√≥“°“√¥â“π«‘∑¬“»“ μ√å°“√Õ“À“√ ‚¿™π“°“√·≈– ÿ¢¿“æ

¡ÒúÙóҡÒ÷ҧÇÔ·ÂÒÈÒÊμÏ¡ÒÃÍÒËÒà âÀª¹Ò¡Òà áÅÐ ÊØ¢ÀÒ¾¢Í§Ç§¡ÒÃâÀª¹Ò¡ÒÃä·ÂÁÕ¤ÇÒÁÊÓ¤ÑÞÍ‹ҧÂÔè§ à¹×èͧ¨Ò¡ ÍÒËÒ÷Õè ´Õ ÁÕ ¤Ø ³ ÀÒ¾μŒ Í §¶Ù ¡ ËÅÑ ¡ âÀª¹Ò¡Òà ´Ñ § ¹Ñé ¹ ¶Œ Ò ¹Ñ¡ÇÔ·ÂÒÈÒÊμÏ¡ÒÃÍÒËÒäӹ֧¶Ö§ÊÔè§àËÅ‹Ò¹Õé¡ç¨Ð·ÓãËŒ¤¹ä·Â ÁÕ·Ò§àÅ×Í¡·ÕèàËÁÒÐÊÁ ઋ¹ ã¹Í´Õμ·ÕèÁÕ»˜ÞËÒ¡ÒâҴ¸ÒμØàËÅç¡ áÅÐäÍâÍ´Õ¹ ä´ŒÁÕ¡ÒÃËÇÁÁ×͡ѹ¢Í§½†ÒÂÇÔªÒ¡ÒÃáÅн†Ò¼ٌ¼ÅÔμ ÍØμÊÒË¡ÃÃÁÍÒËÒÃà¾×èÍËÒÇÔ¸Õá¡Œ»˜ÞËҴѧ¡Å‹ÒÇ ¨¹¡ÃзÑè§ä´ŒÁÕ ¡ÒÃàμÔÁ¸ÒμØàËÅç¡áÅÐäÍâʹչŧ㹺ÐËÁÕèÊÓàÃç¨ÃÙ» «Öè§ä´ŒÃѺ ¤ÇÒÁ¹ÔÂÁ㹡ÒúÃÔâÀ¤¤‹Í¹¢ŒÒ§ÁÒ¡ ÃÇÁ·Ñ駡ÒÃàμÔÁ¸ÒμØàËÅç¡ ã¹¹éÓ»ÅÒáÅЫÕÍÔêÇ ËÃ×͡óաÒþº»˜ÞËÒ¡ÒâҴÇÔμÒÁÔ¹àÍ ¡çä´ŒÁÕ¡ÒÃàμÔÁÇÔμÒÁÔ¹àÍŧ㹹Á¢Œ¹ËÇÒ¹ ÃÇÁ件֧¡ÒÃàμÔÁÊÒà ÍÒËÒÃÍ×è¹ æ ·Õè໚¹»˜ÞËÒ¡ÒâҴŧä»ã¹ÍÒËÒà ª¹Ô´μ‹Ò§ æ ËÃ×Í¡ÒüÅÔμÍÒËÒÃâ´ÂÅ´ËÇÒ¹ Áѹ à¤çÁ à¾×èÍÅ´»ÃÔÁÒ³¼ÙŒ»†Ç·Õè໚¹âä-

8

àºÒËÇÒ¹ËÃ×Íâääμ ໚¹μŒ¹ ¨ÐàËç¹Ç‹ÒËÒ¡ÍØμÊÒË¡ÃÃÁÍÒËÒÃãËŒ¤ÇÒÁËÇÁÁ×Í໚¹Í‹ҧ´Õ ¡Ñº½†ÒÂâÀª¹Ò¡Òáç¨Ð·ÓãËŒà¡Ô´¡ÒþѲ¹ÒÊØ¢ÀҾ͹ÒÁÑ¢ͧ ¤¹ä·Âä´Œ â´Â੾ÒÐÍ‹ҧÂÔè§μŒÍ§ÊÌҧ¹ÔÊÑ¡ÒÃÍÍ¡¡ÓÅѧ¡Ò á¹Ð¹Ó¤¹ä·ÂãËŒÃÙŒ¨Ñ¡àÅ×Í¡ºÃÔâÀ¤ÍÒËÒ÷Õè¶Ù¡μŒÍ§ àËÁÒÐÊÁáÅÐ ÊÍ´¤ÅŒÍ§¡ÑºËÅÑ¡âÀª¹Ò¡Òà ÃÙŒ¨Ñ¡¡ÒÃÍ‹Ò¹©ÅÒ¡âÀª¹Ò¡ÒÃà¾×èÍ ÊÒÁÒöàÅ×Í¡ÍÒËÒ÷ÕèàËÁÒСѺÊØ¢ÀÒ¾¢Í§μ¹ ËÅÕ¡àÅÕ觡Òà ºÃÔ â À¤¹é Ó ÍÑ ´ ÅÁ·ÕèÁÕ Ã ÊËÇÒ¹áÅФÇÒÁ໚ ¹ ¡Ã´ÊÙ § â´ÂàÅ× Í ¡ ºÃÔâÀ¤¹éÓ¼ÅäÁŒËÃ×ͼÅäÁŒÊ´·Õè»ÃСͺ仴ŒÇÂàÊŒ¹ãÂÍÒËÒà áÅÐ ÇÔμÒÁÔ¹ËÅÒª¹Ô´ ¨Ö§¨Ð·ÓãËŒ¾ÄμÔ¡ÃÃÁ¡ÒúÃÔâÀ¤¢Í§¤¹ä·Â à»ÅÕè¹á»Å§ä»Í‹ҧ¶Ù¡μŒÍ§μÒÁËÅÑ¡âÀª¹Ò¡ÒÃμÒÁμŒÍ§¡Òà §«“¡·μ°μà“ߢÕß‚¿™π“°“√„πª√–‡∑»‰∑¬·≈– “°≈

ËÒ¡à»ÃÕºà·Õº´ŒÒ¹ÍÒËÒÃáÅÐâÀª¹Ò¡Òâͧ»ÃÐà·Èä·Â áÅÐÃдѺÊÒ¡Å ¨Ð¾ºÇ‹ÒÍÒËÒÃä·Âá·Œáμ‹´Ñé§à´ÔÁ¹Ñé¹»ÃÐ¡Íºä» ´ŒÇ¼ѡ ¼ÅäÁŒáÅÐÍÒËÒ÷ÕèÁÕÊÒÃÍÒËÒäú¶ŒÇ¹ ઋ¹ ¼Ñ¡μŒÁ ¹éÓ¾ÃÔ¡»ÅÒ·Ù ËÃ×ÍᡧʌÁ ໚¹μŒ¹ ã¹¢³Ð·ÕèÍÒËÒÃÊÒ¡ÅʋǹãËÞ‹ ໚¹ÍÒËÒèҹ´‹Ç¹·Õè»ÃСͺ´ŒÇ¤ÒÏâºäÎà´ÃμáÅÐä¢Áѹ໚¹ ËÅÑ¡ ·ÓãËŒ¤¹ä·Âä´ŒÃѺÍÒËÒ÷Õè໚¹»ÃÐ⪹áÅÐä´Œà»ÃÕºÊÒ¡Å Í‹ҧÁÒ¡ ¶ŒÒËÒ¡Âѧ¤§ºÃÔâÀ¤ÍÒËÒÃä·ÂÊÁèÓàÊÁÍμ‹Íä» ã¹»˜¨¨ØºÑ¹¼ÙŒ»ÃСͺÍÒËÒÃËÃ×͹ѡÇÔªÒ¡ÒÃã¹μ‹Ò§»ÃÐà·Èä´Œ àÅç § àËç ¹ »˜ Þ ËÒ´Ñ § ¡Å‹ Ò Ç àª‹ ¹ ¼ÙŒ » ÃСͺÍÒËÒêÒÇÍÑ § ¡ÄÉä´Œ ¾ÂÒÂÒÁà»ÅÕè¹¾ÄμÔ¡ÃÃÁ¡ÒúÃÔâÀ¤¢Í§à´ç¡ÇÑÂàÃÕ¹ «Ö觺ÃÔâÀ¤áμ‹ ÍÒËÒèҹ´‹Ç¹ ãËŒËѹÁÒºÃÔâÀ¤¼Ñ¡ ¼ÅäÁŒáÅÐà¹×éÍÊÑμǏÁÒ¡¢Öé¹ áμ‹äÁ‹ä´ŒÃѺ¡ÒÃʹѺʹع¨Ò¡¼ÙŒ»¡¤ÃͧáÅÐμÑÇà´ç¡àͧ ´ŒÇ¤ÇÒÁ äÁ‹à¢ŒÒ㨶֧ËÅÑ¡âÀª¹Ò¡Ò÷Õè¶Ù¡μŒÍ§ ´Ñ§¹Ñ鹡ÒÃà»ÅÕè¹¾ÄμÔ¡ÃÃÁ ¡ÒúÃÔâÀ¤¨Ö§¤ÇÃàÃÔèÁμÑé§áμ‹ÇÑÂà´ç¡â´ÂÁÕ¤Ãͺ¤ÃÑÇãËŒ¡ÒÃʹѺʹع´ŒÇ ∫∑∫“∑¢ÕߺŸâ‡°’ˬ«¢âÕß„π°“√æ—≤π“ß“π¥â“πÕ“À“√ ·≈–‚¿™π“°“√¢Õߪ√–‡∑»‰∑¬

à¾×èÍãËŒ§Ò¹´ŒÒ¹ÍÒËÒÃáÅÐâÀª¹Ò¡Òâͧ»ÃÐà·Èä·Âä´ŒÃѺ ¡ÒþѲ¹ÒãËŒ¡ŒÒÇ˹ŒÒáÅÐ໚¹»ÃÐ⪹μ‹Í»ÃЪҪ¹Í‹ҧ᷌¨ÃÔ§ ÈÒÊμÃÒ¨ÒÏà¡ÕÂÃμԤس ´Ã.ÊÔÃÔ¹·Ã ¾ÔºÙŹÔÂÁ ์¹Ç‹ÒÍÂÒ¡ãËŒ ¤¹ä·Â¹ÔÂÁºÃÔâÀ¤ÍÒËÒÃä·Â ÍÒËÒà ·Õè à »š ¹ ¸ÃÃÁªÒμÔ ä Á‹ ÁÕ ¡ÒûÃØ § áμ‹ § ÁÒ¡

««““√  «“√ “√‚¿™π“°“√ √ ““√√‚¿™π ‚¿™™ππ““°°“√ ‚¿ “√

R1_Nutrition_p5-9_pro1.indd Sec1:8

6/22/09 9:42:13 PM


à¡Ô¹ä» áÅÐä´ŒÃѺÍÒËÒ÷Õè»ÅÍ´ÀÑ à¾×èÍãËŒ¤Ø³¤‹ÒªÕÇÔμ¢Í§¤¹ä·Â´Õ¢Öé¹ ÍÒËÒâͧ¤¹ä·Â¤ÇÃÁդسÀÒ¾ »ÃÒȨҡÊÒþÔÉáÅÐÊÒû¹à»„œÍ¹ àÃÔèÁμŒ¹¨Ò¡à¡ÉμáäÇÃμÃÐ˹ѡ¶Ö§¤Ø³ÀÒ¾ªÕÇÔμ¢Í§¼ÙŒºÃÔâÀ¤ ໚¹ËÅÑ¡ äÁ‹ãªŒÊÒÃà¤ÁÕ㹡ÒûÅÙ¡¾×ª ¨Ò¡¹Ñ鹤ÇÃÁÕ¡ÒÃó礏 à»ÅÕè¹á¹Ç¤Ô´áÅÐÁØÁÁͧ¢Í§¼ÙŒ¼ÅÔμ·Ò§´ŒÒ¹ÍØμÊÒË¡ÃÃÁÍÒËÒà ãËŒ´ÙáÅÍÒËÒÃãËŒÁÕ¤ÇÒÁ»ÅÍ´ÀÑ äÁ‹¼ÅÔμÍÒËÒ÷Õè¼Ô´ÈÕŸÃÃÁ ¨ÃÔ¸ÃÃÁáÅÐäÁ‹¤´â¡§»ÃЪҪ¹ ʋǹÀÒ¤ÃÑ°áÅйѡÇÔªÒ¡Òà μŒÍ§ãËŒ¢ŒÍÁÙÅ·Õè¶Ù¡μŒÍ§·Ò§´ŒÒ¹ÍÒËÒà âÀª¹Ò¡Òà ÁÕ¹âºÒ ʹѺʹعãËŒà¡Ô´¡ÒáԹ´ÕÍÂÙ‹´Õ¢Í§»ÃЪҪ¹ Ê‹§àÊÃÔÁ¼ÙŒ´ŒÍÂâÍ¡ÒÊ

ãËŒÁÕÊÔ·¸Ôà·‹Òà·ÕÂÁ¡Ñ¹ ÊÁÒ¤ÁâÀª¹Ò¡ÒÃÏ ¨Ö§Ã‹ÇÁ໚¹Ê‹Ç¹Ë¹Öè§ ã¹¡ÒÃãËŒ¢ŒÍÁÙÅ´ŒÒ¹âÀª¹Ò¡ÒÃá¡‹»ÃЪҪ¹ ¼ÙŒ»ÃСͺ¡Òà ÍØμÊÒË¡ÃÃÁÍÒËÒáçμŒÍ§¼ÅÔμÍÒËÒÃãËŒ¶Ù¡μŒÍ§ã¹·Ø¡¢Ñé¹μ͹ μÑé§áμ‹ÇÑμ¶Ø´Ôº¨¹¶Ö§Á×ͼٌºÃÔâÀ¤ (Farm to table) â´Â¤Ó¹Ö§¶Ö§ ¤ÇÒÁ»ÅÍ´ÀÑ¢ͧÅÙ¡¤ŒÒ໚¹ËÅÑ¡ ͧ¤¡ÃÍÔÊÃÐμŒÍ§ÁÕÍӹҨ㹠¡ÒÃμÑ¡àμ×͹áÅÐʹѺʹعãËŒÁÕâÀª¹Ò¡Ò÷Õè¶Ù¡μŒÍ§ áÅзÕèÊÓ¤ÑÞ μŒÍ§à»š¹»Ò¡àÊÕ§ãËŒ»ÃЪҪ¹ ËÇѧ໚¹Í‹ҧÂÔè§Ç‹ÒàÊŒ¹·Ò§ÊÒÂâÀª¹Ò¡ÒÃàÊŒ¹¹Õé ¨Ð໚¹Ë¹Öè§ã¹ ˹·Ò§·Õè¨Ð¹Ó¤¹ä·Âä»ÊÙ‹¡ÒÃÁդسÀÒ¾ªÕÇÔμ·Õè´Õã¹Í¹Ò¤μ

μ”·Àπàßß“π∑“ߥâ“π‚¿™π“°“√

• • • • • • •

·Õè»ÃÖ¡ÉÒÊÁÒ¤ÁâÀª¹Ò¡ÒÃáË‹§»ÃÐà·Èä·Âã¹¾ÃкÃÁÃÒªÙ»¶ÑÁÀ¢Í§ÊÁà´ç¨¾ÃÐà·¾ÃÑμ¹ÃÒªÊØ´ÒÏ ÊÂÒÁºÃÁÃÒª¡ØÁÒÃÕ ÇØزÔÍÒÊÒ¸¹Ò¤ÒÃÊÁͧÊÒ¢ÒÊØØ¢ÀÒ¾ Í´Õμ¼ÙŒÍӹǡÒÃáÅмٌ¡‹ÍμÑé§ÇÔ·ÂÒÅѹҹҪÒμÔ ÁËÒÇÔ·ÂÒÅÑÂÁËÔ´Å (Mahidol University International College |; MUIC) Í´Õμ¼ÙŒÍӹǡÒÃʶҺѹÇÔ¨ÑÂáÅоѲ¹ÒÇÔ·ÂÒÈÒÊμÏáÅÐà·¤â¹âÅÂÕ ÁËÒÇÔ·ÂÒÅÑÂÁËÔ´Å Í´ÕμÃͧ͸ԡÒú´Õ½†ÒÂÇԨѠÁËÒÇÔ·ÂÒÅÑÂÁËÔ´Å Í´Õμ¼ÙŒÍӹǡÒÃÈٹÈÒÅÒÂÒ ÁËÒÇÔ·ÂÒÅÑÂÁËÔ´Å Í´Õμ¹Ò¡ÊÁÒ¤ÁâÀª¹Ò¡ÒÃáË‹§»ÃÐà·Èä·ÂÏ

ªï∑’Ë 43 ©∫—∫∑’Ë 4 μÿ≈“§¡ - ∏—𫓧¡ 2551

R1_Nutrition_p5-9_pro1.indd Sec1:9

9

6/22/09 9:42:13 PM


Nutrition

Interview

ÊÑÁÀÒɳáÅÐàÃÕºàÃÕ§â´Â ÊؾԪÞÒ ÈÃÕÀÁà sr.supichaya@foodfocusthailand.com

ICN 2009

‚¿™π»“ μ√å . .. °“√ª√–™ÿ¡‚¿™π“°“√√–¥—∫‚≈° ‡À≈◊ Õ ‡«≈“Õ’ ° ‡æ’ ¬ ߉¡à π “π°à Õ π∑’Ë ß “π ª√–™ÿ ¡ «‘ ™ “°“√‚¿™π“°“√π“π“™“μ‘ §√—È ß ∑’Ë 19 [the 19th International Congress of Nutrition (ICN 2009)] ®–‡√‘Ë¡μâπ¢÷Èπ„π«—π∑’Ë 4-9 μÿ≈“§¡ 2552  ¡“§¡‚¿™π“°“√·Àà ß ª√–‡∑»‰∑¬ „πæ√–∫√¡√“™Ÿ ª ∂— ¡ ¿å   ¡‡¥Á ® æ√–‡∑æ√— μ π√“™ ÿ ¥ “ œ  ¬“¡∫√¡√“™°ÿ ¡ “√’ „π∞“π–‡®â“¿“æ„π°“√®—¥ß“πª√–™ÿ¡œ ∑’Ë ”§—≠√–¥—∫‚≈° ·≈–π—∫‡ªìπ§√—Èß·√° ¢Õߪ√–‡∑»‰∑¬∑’Ë ‰ ¥â √— ∫ ‚Õ°“ ‡ªì π ‡®â“¿“æ¢Õß°“√®—¥ß“πª√–™ÿ¡ «— π π’È ∑’ ¡ ß “ π ‰ ¥â √— ∫ ‡ °’ ¬ √ μ‘ ® “ ° √Õß»“ μ√“®“√¬å ¥√.‡Õ¡Õ√ « —πμ«‘ ÿ∑∏‘Ï „π∞“π–ª√–∏“π§≥–°√√¡°“√¥â “ π «‘ ™ “°“√∑’Ë ® –¡“„Àâ ¢â Õ ¡Ÿ ≈ ‡°’Ë ¬ «°— ∫ °“√ ®—¥μ“√“ß°“√ª√–™ÿ¡§√—Èßπ’È

10

«“√ “√‚¿™π“°“√

R1_Nutrition_p10-13_pro1.indd Sec1:10

6/22/09 10:36:42 PM


®ÿ¥‡√‘Ë¡‡≈Á°Ê ¢Õ߇√◊ËÕß√–¥—∫‚≈°

°“√‡μ√’¬¡ß“π„π∞“π–ºŸâ¥Ÿ·≈∑“ß«‘™“°“√

¡‹Í¹Í×è¹μŒÍ§¢Íá¹Ð¹ÓãËŒÃÙŒ¨Ñ¡¡Ñº¡ÒûÃЪØÁ·Ò§ÇÔªÒ¡ÒôŒÒ¹ âÀª¹Ò¡ÒùҹҪÒμÔ ËÃ×Í International Congress of Nutrition ¡‹Í¹Ç‹Ò໚¹¡ÒûÃЪØÁ·Õè´Óà¹Ô¹¡ÒÃÀÒÂãμŒ¡ÒáӡѺ ´ÙáÅáÅÐʹѺʹع¢Í§Ê˾ѹ¸¹Ò¹ÒªÒμÔ´ŒÒ¹âÀª¹ÈÒÊμÏ ËÃ×Í The International Union of Nutritional Sciences; IUNS Ê˾ѹ¸´Ñ§¡Å‹ÒÇ»ÃСͺ仴ŒÇÂÊÁÒªÔ¡·Õè໚¹ÊÁÒ¤ÁâÀª¹Ò¡Òà 㹻ÃÐà·Èμ‹Ò§ æ ·Ø¡ÀÙÁÔÀÒ¤·ÑèÇâÅ¡ ઋ¹ àÍàªÕ ÍàÁÃÔ¡Ò áÍ¿ÃÔ¡Ò à»š¹μŒ¹ â´Â§Ò¹»ÃЪØÁÇÔªÒ¡ÒÃâÀª¹Ò¡ÒùҹҪÒμÔ¹Õé ¨Ð¨Ñ´¢Öé¹·Ø¡æ 4 »‚ â´ÂãËŒ »ÃÐà·ÈÊÁÒªÔ ¡ ËÁØ ¹ àÇÕ Â ¹¡Ñ ¹ àʹÍμÑ Ç à»š ¹ ਌ Ò ÀÒ¾ «Öè § »ÃÐà·ÈÊÁÒªÔ¡¨ÐμŒÍ§¹ÓàÊ¹Í ´Œ Ò ¹ ¤ Ç Ò Á ¾ ÃŒ Í Á ã ¹ ¡ Ò Ã àμÃÕÂÁ¡Òà ¢ŒÍ´Õ¢Í§»ÃÐà·Èμ¹ áÅТŒÍÁÙÅ´ŒÒ¹Í×è¹ æ à¾×èÍãËŒ ¼ÙŒ á ·¹¢Í§ÊÁÒªÔ ¡ã¹ÊË¾Ñ ¹ ¸ ŧ¤Ðá¹¹àÅ× Í ¡»ÃÐà·È·Õè àËÁÒÐÊÁáÅÐÁÕ ¤ ÇÒÁ¾ÃŒ Í Á ·ÕèÊØ´·Õè¨ÐÁÒÃѺμÓá˹‹§à¨ŒÒÀÒ¾ Íѹ·Ã§à¡ÕÂÃμÔ¹Õé

ËÅѧ¨Ò¡·Õèä´ŒÃѺàÅ×Í¡ãˌ໚¹ ਌ÒÀÒ¾¡ÒèѴ§Ò¹»ÃЪØÁã¹ ¤ÃÑ駹Õé ¡ÒÃàμÃÕÂÁ¤ÇÒÁ¾ÃŒÍÁä´ŒàÃÔèÁμŒ¹¢Öé¹Í‹ҧ໚¹·Ò§¡ÒÃàÁ×èÍ »ÃÐà·Èä·Âä´ŒÃѺÁͺËÁÒ§ҹμ‹Í¨Ò¡»ÃÐà·ÈáÍ¿ÃÔ¡ÒãμŒ «Öè§ à»š¹à¨ŒÒÀÒ¾¡ÒûÃЪØÁ¤ÃÑé§Å‹ÒÊØ´ (¾.È. 2549) ¼ÙŒ·Õè´ÓçμÓá˹‹§ ¹Ò¡ÊÁÒ¤ÁÏ ã¹¢³Ð¹Ñé ¹ ¤× Í ÈÒÊμÃÒ¨ÒÏ à ¡Õ Â ÃμÔ ¤Ø ³ ¹¾.à·¾ ËÔÁзͧ¤Ó ä´ŒáÊ´§¤ÇÒÁ¾ÃŒÍÁâ´ÂÁÕ¡ÒèѴ¡Òà áÊ´§¾×鹺ŒÒ¹¢Í§»ÃÐà·Èä·ÂáÅШѴ§Ò¹¹Ô·ÃÃÈ¡Ò÷ҧÇÔªÒ¡Òà ËÅѧ¨Ò¡¹Ñé¹ ÃÈ.´Ã.àÍÁÍà 䴌ÃѺÁͺËÁÒÂãˌ໚¹»Ãиҹ ¤³Ð¡ÃÃÁ¡ÒôŒ Ò ¹ÇÔ ª Ò¡ÒáÒà »ÃЪØÁ àÁ×èÍä´ŒÃѺ§Ò¹áÅŒÇä´ŒÁÕ¡Òà ¨Ñ ´ μÑé § ¤³Ð¡ÃÃÁ¡ÒÃÇÔ ª Ò¡Òèҡ ¼ÙŒ·Ã§¤Ø³ÇزÔã¹»ÃÐà·È áÅÐàÃÔèÁμŒ¹ ÃǺÃÇÁ¢ŒÍÁÙÅáÅФÇÒÁ¤Ô´àË繨ҡ ¼ÙŒàªÕèÂǪÒÞ ´ŒÒ¹âÀª¹ÈÒÊμÏ·Ñé§ã¹ »ÃÐà·ÈáÅÐμ‹ Ò §»ÃÐà·È áÅÐ »ÃÐà·ÈÊÁÒªÔ¡μ‹Ò§ æ ·ÑèÇâÅ¡¢Í§ ÊË¾Ñ ¹ ¸ IUNS Ç‹ Ò ÁÕ ¢Œ Í àʹÍá¹Ð ËÃ×ͤÇÒÁ¤Ò´ËÇѧμ‹Í ICN 2009 Í‹ҧäà áÅÐÊÔè§ã´·ÕèμŒÍ§¡ÒÃãËŒ·Ó à¾×è Í à»š ¹ ·Õè » ÃÐ¨Ñ ¡ ɏ á ÅÐá¾Ã‹ Ë ÅÒ ·ÑèÇä»

ª√–°“»§«“¡æ√âÕ¡  Ÿàª√–‡∑» ¡“™‘°

§«“¡§“¥À«—ßÕ—π𔉪 Ÿà°“√

àÁ×è Í 8 »‚ ·Õè ¼‹ Ò ¹ÁÒ æ—≤𓂪√·°√¡°“√ª√–™ÿ¡ √Õß»“ μ√“®“√¬å ¥√.‡Õ¡Õ√ « —πμ«‘ ÿ∑∏‘Ï ¡ÒûÃЪØÁä´Œ¨Ñ´¢Öé¹ ³ ¡Ãا¨Ò¡¡ÒÃÃǺÃÇÁáÅлÃÐàÁÔ¹¼Å ª√–∏“π§≥–°√√¡°“√¥â“π«‘™“°“√ àÇÕ Â ¹¹Ò »ÃÐà·ÈÍÍÊàμÃÕ Â ¢ŒÍÁÙŴѧ¡Å‹ÒÇ ¾ºÇ‹Ò¤ÇÒÁ¤Ò´ËÇѧ ¢Õß°“√®—¥ª√–™ÿ¡ the 19th International » Ã Ð à · È ä · Ââ ´ Â Ê Á Ò ¤ Á Congress of Nutrition (ICN 2009) ËÅÑ ¡ ·Õè μŒ Í §¡ÒÃãËŒ à ¡Ô ´ ¢Öé ¹ 㹡Òà âÀª¹Ò¡ÒÃáË‹ § »ÃÐà·Èä·ÂÏ »ÃЪØÁ¤ÃÑ駷Õè 19 ¹Õé ¤×Í 1) ¡Òà «Öè § ã¹¢³Ð¹Ñé ¹ ¼ÙŒ ·Õè ´ ÓçμÓá˹‹ § ¹Ò¡ÊÁÒ¤ÁÏ ¤× Í »ÃЪØÁ·ÕèÁÕà¹×éÍËÒÊÒÃдŒÒ¹ÇÔªÒ¡ÒÃÍ‹ҧ ࢌÁ¢Œ¹áÅзѹÊÁÑ ÃͧÈÒÊμÃÒ¨ÒÏ ´Ã.ÊØ»ÃÒ³Õ á¨Œ§ºÓÃا áÅÐÀÒ¤Õà¤Ã×Í¢‹Ò ÃÇÁ¶Ö§¤ÇÒÁ¡ŒÒÇ˹ŒÒ§Ò¹ÇԨѴŒÒ¹ âÀª¹ÈÒÊμÏã¹Í¹Ò¤μ áÅÐ Íѹ䴌ᡋ ¡ÃÁ͹ÒÁÑ ¡ÃзÃǧÊÒ¸ÒóÊØ¢ ʶҺѹÇÔ¨ÑÂ- 2) ãËŒÁÕ¡ÒÃʹѺʹع¹Ñ¡ÇÔªÒ¡ÒÃÃØ‹¹ãËÁ‹ãˌ䴌ÃѺâÍ¡ÒÊࢌÒËÇÁ¿˜§ âÀª¹Ò¡Òà ÁËÒÇÔ·ÂÒÅÑÂÁËÔ´Å ¤³Ðá¾·ÂÈÒÊμÏâç¾ÂÒºÒÅ ÊÑÁÁ¹Ò·Ò§ÇÔªÒ¡Òà à¹×èͧ¨Ò¡¡ÒûÃЪØÁã¹ËÅÒÂ æ ¤ÃÑé§ ÃÒÁÒ¸Ô º ´Õ ÁËÒÇÔ · ÂÒÅÑ Â ÁËÔ ´ Å ¤³ÐàǪÈÒÊμÏ à ¢μÃŒ Í ¹ ·Õ輋ҹÁҼٌࢌÒËÇÁ»ÃЪØÁʋǹãËÞ‹¨Ð໚¹¹Ñ¡ÇÔªÒ¡ÒÃÃдѺÍÒÇØâÊ ÁËÒÇÔ·ÂÒÅÑÂÁËÔ´Å ¤³ÐÊÒ¸ÒóÊØ¢ÈÒÊμÏ ÁËÒÇÔ·ÂÒÅÑ àÁ×è Íä´Œ ¢Œ Í ÊÃØ » áÅŒ Ç ¨Ö §ä´Œ ¡ Ó˹´á¹Ç·Ò§ã¹¡ÒÃ¨Ñ ´ §Ò¹ ÁËÔ´Å ¤³ÐÊËàǪÈÒÊμÏ ¨ØÌÒŧ¡Ã³ÁËÒÇÔ·ÂÒÅÑ áÅÐ ÀÒÂãμŒËÑÇ¢ŒÍ “Nutrition Security for All” áÅСÓ˹´ËÑÇ¢ŒÍ‹Í ÁÙŹԸÔÊÒ¸ÒóÊØ¢áË‹§ªÒμÔ ä´Œª‹Ç¡ѹ»ÃЪÒÊÑÁ¾Ñ¹¸à¼Âá¾Ã‹¶Ö§ ·Õèà¡ÕèÂÇ¢ŒÍ§·Ñé§ÊÔé¹ 13 ¢ŒÍ‹Í ·Õè¤Ãͺ¤ÅØÁ»˜¨¨Ñ¡Ó˹´·Õè ¤ÇÒÁ¾ÃŒÍÁ㹡ÒÃ໚¹à¨ŒÒÀÒ¾¢Í§»ÃÐà·Èä·Âãˌᡋ»ÃÐà·È à¡ÕèÂÇ¢ŒÍ§â´Âμç (proximal determinants) áÅл˜¨¨Ñ ÊÁÒªÔ¡ áÅдŒÇ»˜ÞËÒ¤ÇÒÁÃعáçÀÒÂã¹»ÃÐà·È¤Ù‹á¢‹§¤×Í ¡Ó˹´´ŒÒ¹ÊÔè§áÇ´ÅŒÍÁ Êѧ¤ÁáÅÐÇѲ¹¸ÃÃÁ ¨Ò¡¹Ñ鹨֧¹Ó 13 ÍÔÊÃÒàÍÅ ·ÓãËŒ»ÃÐà·Èä·Âä´ŒÃѺªÑª¹Ð¨Ò¡¡ÒÃŧ¤Ðá¹¹ ¢ŒÍ‹ÍÂÁҨѴ¡ÅØ‹Á ä´Œ·Ñé§ËÁ´ 3 á¹Ç·Ò§ (cascade) ºÇ¡ 1 àÊէ͋ҧ໚¹àÍ¡©Ñ¹· ÁÔμÔ â´Âáμ‹ÅÐá¹Ç·Ò§»ÃСͺ仴ŒÇÂËÑÇ¢ŒÍ‹Í·Õèà¡ÕèÂÇ¢ŒÍ§¡Ñ¹ ªï∑’Ë 43 ©∫—∫∑’Ë 4 μÿ≈“§¡ - ∏—𫓧¡ 2551

R1_Nutrition_p10-13_pro1.indd Sec1:11

11

6/22/09 10:36:42 PM


Íѹ¹Óä»ÊÙ‹ËÑÇ¢ŒÍ㹡ÒÃÍÀÔ»ÃÒ «Öè§áμ‹ÅÐá¹Ç·Ò§¨Ð¤Ãͺ¤ÅØÁ ¡ÒùӤÇÒÁÃÙŒä»ÊÙ‹¡ÒûÃÐÂØ¡μãªŒ ´Ñ§ÀÒ¾ á¹Ç·Ò§áá ¤×Í Í§¤¤ÇÒÁÃÙŒ´ŒÒ¹âÀª¹ÈÒÊμÏàªÔ§ÅÖ¡ áÅÐ ÁÒμáÒ÷ҧÍÒËÒÃáÅÐâÀª¹ÈÒÊμÏ·Õè໚¹μŒ¹áºº á¹Ç·Ò§¹Õé ẋ§à»š¹ËÑÇ¢ŒÍ੾ÒÐä´Œ 4 ËÑÇ¢ŒÍ ¤×Í 1) ¤ÇÒÁμŒÍ§¡ÒÃÊÒÃÍÒËÒà áÅÐàÁμÒºÍÅÔ «Ö Á 2) ¡ÒûÃÐàÁÔ ¹ ÀÒÇÐâÀª¹Ò¡Òà 3) âÀª¹Ò¡ÒäÅÔ¹Ô¡ áÅÐ 4) ÁÒμáÒ÷ҧÍÒËÒà à¾×è͹Óä»ÊÙ‹ÀÒÇÐâÀª¹Ò¡Ò÷ÕèàËÁÒÐÊÁ á¹Ç·Ò§·ÕèÊͧ ¤×Í ¡ÒúÙóҡÒôŒ Ò ¹à¡Éμà ÃкºÍÒËÒà ÍÒËÒþ×é ¹ ºŒ Ò ¹áÅÐ¤Ø ³ ÀÒ¾ ¢Í§ÍÒËÒà á¹Ç·Ò§¹Õéẋ§ ໚ ¹ ËÑ Ç ¢Œ Í à©¾ÒÐä´Œ 3 ËÑÇ¢ŒÍ ¤×Í 1) ´ŒÒ¹à¡Éμà áÅÐÃкºÍÒËÒà 2) ÇÑ ² ¹¸ÃÃÁ´Œ Ò ¹ÍÒËÒà áÅÐÍÒËÒþ×é¹àÁ×ͧ áÅÐ 3) ÊÔ·¸Ô㹡ÒÃä´ŒÃѺÍÒËÒà Í‹ҧ¾Íà¾Õ§ á¹Ç·Ò§·Õè Ê ÒÁ ໚ ¹ àÃ×è Í §·Õè ãËÞ‹·ÕèÊØ´ â´Â໚¹¡ÒùÓàÍÒ¤ÇÒÁÃÙŒ ä»ãªŒ ã ¹¡ÒáÓ˹´¹âºÒÂáÅÐá¡Œ ä ¢ »˜ Þ ËÒ à¾×è Í »‡ Í §¡Ñ ¹âäáÅÐÊ‹ § àÊÃÔ Á ÊØ ¢ ÀÒ¾ »ÃСͺ´ŒÇÂËÑÇ¢ŒÍ੾Òж֧ 5 ËÑÇ¢ŒÍ ¤×Í 1) âÀª¹Ò¡Òà áÅСÒÃμÔ´àª×éÍ 2) âä͌ǹáÅÐâääÁ‹μÔ´μ‹ÍàÃ×éÍÃѧ 3) âÀª¹Ò¡Òà μÅÍ´ª‹ Ç §ÍÒÂØ 4) ¹âºÒÂáÅСÒôÓà¹Ô ¹ §Ò¹à¾×è Í ¹Óä»ÊÙ‹ ໇ÒËÁÒ´ŒÒ¹âÀª¹Ò¡ÒÃáÅÐÊØ¢ÀÒ¾ áÅÐ 5) ÁÒμáÒôŒÒ¹ ÍÒËÒÃáÅÐâÀª¹Ò¡ÒÃà¾×èÍÊØ¢ÀÒ¾ ·Ñ駹Õéã¹ÅӴѺ¢Ñé¹ÊØ´·ŒÒ¹Ñé¹à»š¹¡ÒùÓàÍÒ¤ÇÒÁÃÙŒ¨Ò¡á¹Ç·Ò§ ·Õè 1 áÅÐ 2 ÁÒ»ÃÐÂØ¡μãªŒâ´Â¼ÙŒÃѺ¼Ô´ªÍº´ŒÒ¹ÊÒ¸ÒóÊØ¢¢Í§ ¡ÃзÃǧ ·ºÇ§ ¡ÃÁ áÅÐ˹‹Ç§ҹμ‹Ò§ æ ÍÒ·Ôઋ¹ ¡ÃÁ͹ÒÁÑ ¡ÃÁ¤Çº¤ØÁâä ͧ¤¡ÒÃ͹ÒÁÑÂâÅ¡ ໚¹μŒ¹ à¾×èÍᡌ䢻˜ÞËÒ ·Ò§âÀª¹Ò¡ÒÃã¹Ç§¡ÇŒÒ§

12

¹Í¡¨Ò¡ 3 á¹Ç·Ò§¢ŒÒ§μŒ¹áÅŒÇ ÂѧÁÕÁÔμÔ·Õè໚¹ÀÒ¾ÃÇÁ àª×èÍÁ⧷ءá¹Ç·Ò§à¢ŒÒ´ŒÇ¡ѹ·Õè¤Ãͺ¤ÅØÁ§Ò¹ÇԨѴŒÒ¹âÀª¹ÈÒÊμÏã¹Í¹Ò¤μ ¹ÇÑμ¡ÃÃÁÃдѺ»˜¨à¨¡ºØ¤¤ÅáÅлÃЪҡà à¾×èÍ໚¹»ÃÐ⪹μ‹Í¤ÇÒÁÁÑ蹤§·Ò§âÀª¹Ò¡Òà à¾×èÍãËŒ¡ÒôÓà¹Ô¹¡ÒèѴâ»Ãá¡ÃÁ¡ÒûÃЪØÁÁÕÁÒμðҹ ÃдѺÊÒ¡Å áÅкÃÃÅؤÇÒÁ¤Ò´ËÇѧËÅÑ¡¢ŒÍáá ¨Ö§ä´ŒàªÔÞ ¼ÙŒ · ç¤Ø ³ ÇØ ²Ô ã ¹ÊÒ¢Òμ‹ Ò §æ ·Õè à ¡Õè  ǢŒ Í §¨Ò¡ ÀÙ ÁÔ À Ò¤μ‹ Ò §æ ·Ñé § ÊÔé ¹ 22 ¤¹ ໚ ¹ ¤ ³ Ð ¡ à à Á ¡ Ò Ã ·Õè » ÃÖ ¡ É Ò (International Advisory Committee) à¾×èÍãËŒ¢ŒÍàÊ¹Í á¹Ð¡ÒÃ¨Ñ ´â»Ãá¡ÃÁ¡Òà »ÃÐªØ Á áÅлÃÐàÁÔ ¹ º·¤Ñ´Â‹Í ¡ÒÃä´Œ Á Ò«Öè § »ÃÐà´ç ¹ ¡ÒÃÍÀÔ»ÃÒÂÀÒÂãμŒËÑÇ¢ŒÍ ËÅÑ ¡ ÁÕ ¡ ÒôÓà¹Ô ¹ ¡ÒÃâ´Â àªÔ Þ ¼ÙŒ · ç¤Ø ³ ÇØ ²Ô áÅÐ »ÃСÒÈãËŒ ¹Ñ ¡ ÇÔ ª Ò¡ÒÃàÊ¹Í à¤ŒÒâ¤Ã§μÒÁẺ¿ÍÏÁ·Õè¡Ó˹´ áÅÐÁÕ ¡ ÒûÃÐàÁÔ ¹ à¹×é Í ËÒâ´Â¤³Ð ¼ÙŒ · ç¤Ø ³ ÇØ ²Ô ã ¹ÊÒ¢Ò¹Ñé ¹ æ à¾×è ÍãËŒ ä ´Œ »ÃÐà´ç¹¡ÒÃÍÀÔ»ÃÒÂáÅÐÇÔ·Âҡ÷ÕèàËÁÒÐÊÁ √Ÿª·∫∫¢Õß°“√ª√–™ÿ¡

ÁÕ¡ÒúÃÃÂÒ ÍÀÔ»ÃÒ áÅйÓàʹͼŧҹ·Ò§ÇÔªÒ¡Òà ẺºÃÃÂÒ áÅÐâ»ÊàμÍÏ â´ÂÁÕÃÒÂÅÐàÍÕ´ ´Ñ§¹Õé 1. ¡ÒúÃÃÂÒ (Lecture) 1.1 Keynote áÅÐ Closing 1.2 Plenary 6 àÃ×èͧ 1.3 Cascade 1, 2, 3 + 1 ÁÔμÔ ÃÇÁ 8 àÃ×èͧ 1.4 Special 6 àÃ×èͧ

«“√ “√‚¿™π“°“√

R1_Nutrition_p10-13_pro1.indd Sec1:12

6/22/09 10:36:43 PM


2. ¡ÒÃÍÀÔ»ÃÒ 2.1 Symposium 60 ËÑÇ¢ŒÍ 2.2 Panel discussion 3 ËÑÇ¢ŒÍ 2.3 Round table discussion 6 ËÑÇ¢ŒÍ 2.4 Dialogue 2 ËÑÇ¢ŒÍ 3. ¹Óàʹͼŧҹ·Ò§ÇÔªÒ¡ÒÃẺºÃÃÂÒ áÅÐâ»ÊàμÍÏ â´ÂÁÕ ¹Ñ ¡ ÇÔ ª Ò¡ÒÃÊ‹ § º·¤Ñ ´ ‹ Í ¼Å§Ò¹ÇÔ ¨Ñ  ¡Ç‹ Ò 2,000 àÃ×è Í § ¨Ò¡ 95 »ÃÐà·È·ÑèÇâÅ¡ â»Ãá¡ÃÁ¡ÒÃ¨Ñ ´ »ÃÐªØ Á ÇÔ ª Ò¡ÒäÃÑé § ¹Õé ·Õè ã ªŒ ÃÙ » Ẻ 3 á¹Ç·Ò§ (Cascade) + 1 ÁÔμÔ à¾×èÍãËŒ¼ÙŒà¢ŒÒ»ÃЪØÁ·ÕèÁÒ ¨Ò¡ËÅÒ¡ËÅÒÂÊÒ¢ÒÊÒÁÒöàÅ× Í ¡¿˜ §ã¹á¹Ç·Ò§·Õè μ ¹àͧ ÁÕ ¤ ÇÒÁàªÕè  ǪÒÞ/ʹ㨠¹Í¡¨Ò¡¹Õé ¼ÙŒ à ¢Œ Ò »ÃÐªØ Á ÊÒÁÒö àÅ× Í ¡¿˜ §ã¹ËÑ Ç ¢Œ Í ·Õè μ ¹àͧÁÕ ¤ ÇÒÁʹ㨠áÅÐ¨Ñ ´ àÇÅÒ㹡Òà ࢌҿ˜§Í‹ҧÁÕ»ÃÐÊÔ·¸ÔÀÒ¾ à¹×èͧ¨Ò¡ã¹áμ‹ÅЪ‹Ç§àÇÅÒ¨ÐäÁ‹ÁÕ ËÑÇ¢ŒÍ·Õè«éӡѹ ¤³Ð¼ÙŒ¨Ñ´¡ÒûÃЪØÁ¨Ð¨Ñ´·Ó Roadmap ¢Í§ ËÑÇ¢ŒÍμ‹Ò§ æ à¾×èÍàÍ×éÍÍӹǤÇÒÁÊдǡ㹡ÒÃࢌÒËÇÁ¡Òà »ÃЪØÁ  √â“ß‚Õ°“ „Àâπ—°«‘®—¬√ÿàπ„À¡à

ÊÓËÃÑ º ÇÑ μ ¶Ø » ÃÐʧ¤ ã ¹¢Œ Í ·Õè Ê Í§ ¤× Í ÊÃŒ Ò §âÍ¡ÒÊã��Œ ¹Ñ¡ÇÔ¨ÑÂÃØ‹¹ãËÁ‹ä´Œà¢ŒÒÁÒËÇÁ¡ÒûÃЪØÁ¹Ñé¹ ¤³Ð¡ÃÃÁ¡ÒÃä´ŒÁÕ ¡ÒÃà¨Ã¨Òà¾×è͢ͷعʹѺʹع¨Ò¡Ë¹‹Ç§ҹμ‹Ò§ æ â´Âແ´ âÍ¡ÒÊãËŒ¹Ñ¡ÇÔ¨ÑÂÃØ‹¹ãËÁ‹æ Ê‹§º·¤Ñ´Â‹Í§Ò¹ÇԨѢͧμ¹à¢ŒÒÁÒ ¾Ô ¨ ÒóÒâ´Â¤³Ð¼ÙŒ · ç¤Ø ³ ÇØ ²Ô à¾×è Í ¤Ñ ´ àÅ× Í ¡μÒÁࡳ± ·Õè ¡Ó˹´ ¹Í¡¨Ò¡¹Õé IUNS áÅÐÀÒ¤Õà¤Ã×Í¢‹Ò¨ÐàªÔ޹ѡÇÔ¨ÑÂÃØ‹¹ãËÁ‹·ÕèÁÕ ÈÑ¡ÂÀÒ¾Ê٧ࢌһÃЪØÁÃдÁÊÁͧ¡‹Í¹¡ÒûÃЪØÁ ICN 2009 ´ŒÇ ‡ªÑ“À¡“¬∑’ËμâÕ߉ª„Àâ∂÷ß

¡ÒÃàμÃÕ Â Á¤ÇÒÁ¾ÃŒ Í ÁÍ‹ Ò §àË¹ç ´ à˹×è Í ÂáÅз؋ Á à· ´Ñ§·Õè¡Å‹ÒÇÁÒ¹Ñé¹ à¾×èÍãËŒºÃÃÅØ໇ÒËÁÒ·ÕèÇÒ§äÇŒ ¹Ñ蹡ç¤×Í¡ÒÃ¹Ó àʹͧҹ·Ò§´ŒÒ¹ÇÔªÒ¡Ò÷ÕèÁդسÀÒ¾ ¼ÙŒà¢ŒÒËÇÁ»ÃЪØÁä´ŒÃѺ

¤ÇÒÁÃÙŒ·Õè໚¹»ÃÐ⪹áÅзѹÊÁÑ ¡‹ÍãËŒà¡Ô´áçºÑ¹´ÒÅã¨áÅÐ ¡ÃÐμØŒ¹ãËŒ¡ŒÒÇ仢ŒÒ§Ë¹ŒÒ à¾×èÍãËŒà¡Ô´¡ÒÃÊÌҧà¤Ã×Í¢‹ÒÂáÅÐ ¼Å§Ò¹·ÕèÁÕ»ÃÐ⪹μ‹Íä»ã¹Í¹Ò¤μ áÁŒÇ‹Ò¨Ø´àÃÔèÁμŒ¹ÁÒ¨Ò¡¨Ø´àÅç¡ æ áμ‹ÊÒÁÒö¹Óä»ÊÙ‹¡Òà »ÃЪØÁÃдѺâÅ¡·ÕèÁÕ¤ÇÒÁ¤Ò´ËÇѧÊÙ‹¡ÒþѲ¹Ò´ŒÒ¹âÀª¹ÈÒÊμÏ ¢Í§ÁÇÅÁ¹ØɏÍѹ໚¹à»‡ÒËÁÒ·ÕèμŒÍ§ä»ãËŒ¶Ö§ ´Ñ§¹Ñé¹·Ò§·ÕÁ§Ò¹ ¢ÍËÇÁ໚¹Ê‹Ç¹Ë¹Ö觷Õè¨Ð»ÃСÒȤÇÒÁ¾ÃŒÍÁã¹°Ò¹Ð਌ÒÀÒ¾ ¨Ñ´§Ò¹ãˌ໚¹·Õè»ÃШѡɏᡋ·Ø¡¤¹... “¨Ø´àÃÔèÁμŒ¹àÅç¡ æ ¡‹ÍãËŒà¡Ô´à»‡ÒËÁÒ·ÕèÂÔè§ãËÞ‹” ∫π∑“߇¥‘𠓬‚¿™π»“ μ√å¢Õß √». ¥√. ‡Õ¡Õ√ « —πμ«‘ ÿ∑∏‘Ï

• ·Õè»ÃÖ¡ÉÒÊÁÒ¤ÁâÀª¹Ò¡ÒÃáË‹§»ÃÐà·Èä·Âã¹¾ÃкÃÁ ÃÒªÙ»¶ÑÁÀÊÁà´ç¨¾ÃÐà·¾ÃÑμ¹ÃÒªÊØ´ÒÊÂÒÁºÃÁÃÒª¡ØÁÒÃÕ • »Ãиҹ¤³Ð¡ÃÃÁ¡ÒôŒÒ¹ÇÔªÒ¡Òâͧ¡ÒèѴ»ÃЪØÁ the th 19 International Congress of Nutrition (ICN 2009) • ·Õè»ÃÖ¡ÉÒÍÒÇØâʢͧʶҺѹÇÔ¨ÑÂâÀª¹Ò¡Òà ÁËÒÇÔ·ÂÒÅÑ ÁËÔ´Å • Í´Õμ¼ÙŒÍӹǡÒÃʶҺѹÇÔ¨ÑÂâÀª¹Ò¡Òà ÁËÒÇÔ·ÂÒÅÑ ÁËÔ´Å • Co-Chairperson, United Nations System-Standing Committee on Nutrition-Working Group on Capacity Development • Steering Committee Member of Micronutrient Forum and International Zinc Nutrition Consultative Group • Council Member-World Public Health Nutrition Association • Adjunct Associate Professor, Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, USA

ªï∑’Ë 43 ©∫—∫∑’Ë 4 μÿ≈“§¡ - ∏—𫓧¡ 2551

R1_Nutrition_p10-13_pro1.indd Sec1:13

13

6/22/09 10:36:43 PM


Nutrition

Trend

»ÒÅÕÃÑ° ¤§ÁÒªÕ¾ ªØμÔÁÒ ÈÔÃÔ¡ØŪÂÒ¹¹· ÀÒ¤ÇÔªÒâÀª¹ÇÔ·ÂÒ ¤³ÐÊÒ¸ÒóÊØ¢ÈÒÊμÏ ÁËÒÇÔ·ÂÒÅÑÂÁËÔ´Å

∫∑§—¥¬àÕ

âä͌ Ç ¹à¡Ô ´ ¨Ò¡¡Ò÷Õè Ë Ò §¡ÒÂä´Œ ÃÑ º ¾ÅÑ § §Ò¹¨Ò¡ÍÒËÒÃÁÒ¡¡Ç‹ Ò ¾Åѧ§Ò¹·Õè㪌ä»ã¹¡Ò÷ӡԨ¡ÃÃÁμ‹Ò§æ ¨Ö§·ÓãËŒÁÕ¡ÒÃÊÐÊÁ¢Í§ä¢Áѹ ã¹Ã‹Ò§¡ÒÂμÒÁʋǹμ‹Ò§ æ ¢Í§Ã‹Ò§¡Ò¨¹à»š¹âä͌ǹ à¾ÔèÁ¤ÇÒÁàÊÕ觢ͧ ¡ÒÃà¡Ô´âäàÃ×éÍÃѧ 䴌ᡋ âäàºÒËÇÒ¹ âä¤ÇÒÁ´Ñ¹âÅËÔμÊÙ§ áÅÐâä ËÅÍ´àÅ×Í´áÅÐËÑÇ㨠»˜¨¨ÑÂÊÓ¤ÑÞ·Õè໚¹ÊÒàËμØËÅÑ¡¢Í§âä͌ǹ¤×Í»˜¨¨Ñ ´ŒÒ¹ÊÔè§áÇ´ÅŒÍÁáÅоѹ¸Ø¡ÃÃÁ ¡ÒÃÈÖ¡ÉÒàªÔ§ÅÖ¡ã¹ÃдѺ¾Ñ¹¸Ø¡ÃÃÁ¾ºÇ‹Ò ÂÕ ¹ àÅ»·Ô ¹ ໚ ¹ ÂÕ ¹ ˹Öè § ·Õè ÁÕ ¤ ÇÒÁà¡Õè  ǢŒ Í §¡Ñ º ¡ÒÃà¡Ô ´âä͌ Ç ¹ã¹Á¹Ø É Â ÂÕ¹àÅ»·Ô¹μÑé§ÍÂÙ‹º¹â¤ÃâÁâ«Á¤Ù‹·Õè 7 μÓá˹‹§ q31.3 ·Ó˹ŒÒ·Õè¤Çº¤ØÁ ¡ÒÃÊÌҧÎÍÏâÁ¹àÅ»·Ô¹ã¹à«Åŏä¢Áѹ¢Í§Ã‹Ò§¡Ò ÎÍÏâÁ¹àÅ»·Ô¹·Ó˹ŒÒ·Õè

¬’π‡≈ª∑‘π

°“√°≈“¬æ—π∏ÿå¢Õß °—∫°“√‡°‘¥‚√§Õâ«π »ÃÑ º ÊÁ´Ø Å ¾ÅÑ § §Ò¹¢Í§ Ë Ò § ¡ Ò Â á Å Ð ¤ Ç º ¤Ø Á ¡ÒÃÊÐÊÁ¢Í§ä¢Áѹã¹Ã‹Ò§¡Ò áÅйéÓ˹ѡμÑÇ â´ÂÅ´¡ÒáԹÍÒËÒà áÅÐà¾ÔèÁ¡ÒÃà¼Ò¼ÅÒÞ¾Åѧ§Ò¹ã¹Ã‹Ò§¡Ò àÁ×èÍÎÍÏâÁ¹àÅ»·Ô¹¶Ù¡ËÅÑè§ ÍÍ¡ÁҨзÓãËŒà¡Ô´¤ÇÒÁÃÙŒÊÖ¡ÍÔèÁ ¡ÒáÅÒ¾ѹ¸Ø¢Í§ÂÕ¹àÅ»·Ô¹·ÓãËŒ ¡ÒÃËÅÑ觢ͧÎÍÏâÁ¹àÅ»·Ô¹¼Ô´»¡μÔ ·ÓãËŒºÃÔâÀ¤ÍÒËÒèӹǹÁÒ¡ â´ÂäÁ‹ÃÙŒÊÖ¡ÍÔèÁ ¡ÒÃà¼Ò¼ÅÒÞ¾Åѧ§Ò¹ã¹Ã‹Ò§¡ÒÂÅ´¹ŒÍÂŧ áÅÐà¡Ô´ ¡ÒÃÊÐÊÁ¢Í§ä¢ÁѹμÒÁʋǹμ‹Ò§ æ ¢Í§Ã‹Ò§¡ÒÂà¾ÔèÁ¢Ö鹨¹à»š¹âä͌ǹ ¡ÒÃμÃǨ¾º¡ÒáÅÒ¾ѹ¸Ø¢Í§ÂÕ¹àÅ»·Ô¹¨Ö§à»š¹»ÃÐ⪹μ‹Í¡Òû‡Í§¡Ñ¹ áÅÐᡌ䢻˜ÞËÒâä͌ǹã¹Í¹Ò¤μ 14

¤ÓÊÓ¤ÑÞ: «“√ “√‚¿™π“°“√

âä͌ǹ ÂÕ¹àÅ»·Ô¹ ¾Ñ¹¸Ø¡ÃÃÁ

R1_Nutrition_p14-16_pro1.indd Sec1:14

6/22/09 10:42:58 PM


âä͌ Ç ¹à»š ¹ »˜ Þ ËÒ·Ò§ÊÒ¸ÒóÊØ ¢ ·Õè ÁÕ ¤ ÇÒÁÊÓ¤Ñ Þ áÅÐ Ê‹§¼Å¡Ãзºμ‹ÍÊØ¢ÀÒ¾¢Í§Á¹Øɏ âä͌ǹ໚¹âä·Õèà¡Ô´¨Ò¡ ¤ÇÒÁäÁ‹ÊÁ´ØŢͧ¾Åѧ§Ò¹·Õèä´ŒÃѺ¨Ò¡ÍÒËÒáѺ¾Åѧ§Ò¹·ÕèãªŒä» ã¹¡Ò÷ӡԨ¡ÃÃÁ·Ò§¡Ò ¨Õ§·ÓãËŒà¡Ô´¡ÒÃÊÐÊÁ¢Í§ä¢ÁѹμÒÁ ʋǹμ‹Ò§æ áÅоѲ¹Ò¨¹à¡Ô´à»š¹âä͌ǹ¢Öé¹ä´Œ ¹Í¡¨Ò¡¹Õé âä͌ Ç ¹ÁÕ ¼ Åμ‹ Í ¡ÒÃà¾Ôè Á ¤ÇÒÁàÊÕè  §¢Í§¡ÒÃà¡Ô ´âäàÃ×é Í ÃÑ § μ‹Ò§ æ ઋ¹ âäàºÒËÇÒ¹ âä¤ÇÒÁ´Ñ¹âÅËÔμÊÙ§ áÅÐâä 㹡ÅØ‹ÁËÑÇã¨áÅÐËÅÍ´àÅ×Í´1 ¨Ò¡¢Œ Í ÁÙ Å ·Ò§Ê¶Ô μÔ ¾ºÇ‹ Ò ¤ÇÒÁªØ ¡ ¢Í§à´ç ¡ ·Õè ÁÕ À ÒÇÐ ¹éÓ˹ѡμÑÇà¡Ô¹ã¹»ÃÐà·Èμ‹Ò§ æ ·ÑèÇâÅ¡ Áըӹǹà¾ÔèÁÊÙ§¢Öé¹ Í‹ҧÃÇ´àÃçÇ2 áÅÐÁÕÃÒ§ҹ¡ÒÃÈÖ¡ÉÒ·Õè¡Å‹ÒÇÇ‹Ò ÁÒ¡¡Ç‹Ò ÃŒÍÂÅÐ 70 ¢Í§à´ç¡ÍŒÇ¹ÊÒÁÒö¾Ñ²¹Òä»à»š¹¼ÙŒãËÞ‹·Õè͌ǹ ä´ŒÁÒ¡¡Ç‹Òà´ç¡¹éÓ˹ѡμÑÇ»¡μÔ áÅÐÁÒ¡¡Ç‹ÒÃŒÍÂÅÐ 50 ¢Í§ à´ç¡ÍŒÇ¹μŒÍ§ÊÙÞàÊÕ¤‹Ò㪌¨‹ÒÂ㹡ÒôÙáÅÃÑ¡ÉÒâäμ‹Ò§ æ ·Õè໚¹ ¼ÅÁÒ¨Ò¡âä͌ǹÍÕ¡´ŒÇÂ3 »˜ ¨ ¨Ø ºÑ ¹ âä͌ Ç ¹¾ºä´Œ Á ҡ㹡ÅØ‹ Á ¤¹ã¹»ÃÐà·Èᶺ μÐÇÑ¹μ¡ áÅоºÁÒ¡¢Öé¹ã¹»ÃÐà·È¡ÓÅѧ¾Ñ²¹ÒÍ×è¹ æ ´ŒÇ ʋǹ¢ŒÍÁÙŢͧ»ÃÐà·Èä·Â ÁÕÃÒ§ҹ·Ò§Ê¶ÔμÔ·ÕèáÊ´§¶Ö§¤ÇÒÁ ªØ¡¢Í§¼ÙŒ·Õè໚¹âä͌ǹà¾ÔèÁÊÙ§¢Ö鹡NjÒã¹Í´Õμ4 ¨Ò¡¡ÒÃÃǺÃÇÁ ¢ŒÍÁÙŢͧ¡ÃÁ͹ÒÁÑ ¡ÃзÃǧÊÒ¸ÒóÊØ¢ ¾.È. 2548 ¾ºÇ‹Ò à´ç¡¡‹Í¹ÇÑÂàÃÕ¹áÅÐà´ç¡ÇÑÂàÃÕ¹·Õè¡ÓÅѧÈÖ¡ÉÒã¹ÃдѺ»ÃжÁ ÈÖ¡ÉÒ·ÑèÇ»ÃÐà·È ÁÕÀÒÇÐâÀª¹Ò¡ÒÃà¡Ô¹ÁÒ¡¶Ö§ÃŒÍÂÅÐ 9.7 â´Â¾ºÁÒ¡ã¹ÀÒ¤¡ÅÒ§ ÀÒ¤à˹×Í ÀÒ¤μÐÇѹÍÍ¡à©Õ§à˹×Í áÅÐÀÒ¤ãμŒ μÒÁÅӴѺ5 «Öè§á¹Ç⹌Á·Õèà¾ÔèÁÊÙ§¢Öé¹¹Õé ÁÕÊÒàËμØ ÁÒ¨Ò¡ÇÑ Â à´ç ¡ ໚ ¹ ÇÑ Â ·Õè ÁÕ ¤ ÇÒÁμÃÐË¹Ñ ¡ã¹àÃ×è Í §ÀÒÇйé Ó Ë¹Ñ ¡ μÑǢͧμ¹àͧ¹ŒÍÂáÅÐà´ç¡ÇÑÂàÃÕ¹໚¹¡ÅØ‹Á·Õ辺à´ç¡ÍŒÇ¹à¾ÔèÁ¢Öé¹ Í‹ҧÁÒ¡ â´Â੾ÒÐÍ‹ҧÂÔè§à´ç¡·ÕèÍÒÈÑÂÍÂÙ‹ã¹à¢μàÁ×ͧ ¨Ð¾º ÍÑμÃÒ¤ÇÒÁªØ¡¢Í§âä͌ǹÁÒ¡¡Ç‹Òà´ç¡·ÕèÍÒÈÑÂ㹺ÃÔàdzÍ×è¹ æ ´Ñ§¹Ñé¹à´ç¡¹Ñ¡àÃÕ¹ã¹ÃдѺ»ÃжÁÈÖ¡ÉҨ֧໚¹¡ÅØ‹Á໇ÒËÁÒ·ÕèÁÕ ¤ÇÒÁÊÓ¤ÑÞμ‹Í¡ÒäǺ¤ØÁáÅл‡Í§¡Ñ¹âä͌ǹ à¹×èͧ¨Ò¡¡Òà à¡Ô´âä͌ǹã¹à´ç¡ÁÕ¤ÇÒÁÊÑÁ¾Ñ¹¸μ‹Í¡ÒþѲ¹Ò໚¹¼ÙŒãËÞ‹·Õè͌ǹ áÅÐÊ‹§¼Åμ‹ÍÊØ¢ÀҾ㹡ÒÃà¡Ô´âäμ‹Ò§ æ ·Ñé§ã¹ÃÐÂÐÊÑé¹áÅÐ ÃÐÂÐÂÒÇ ´Ñ § ¹Ñé ¹âä͌ Ç ¹ã¹à´ç ¡ ¨Ö § ¨Ñ ´ä´Œ Ç‹ Ò à»š ¹ »˜ Þ ËÒ·Ò§ ÊÒ¸ÒóÊØ¢·ÕèÁÕ¤ÇÒÁÊÓ¤ÑÞÂÔè§6 âä͌ǹ໚¹âä·ÕèÁÕÊÒàËμآͧ¡ÒÃà¡Ô´âä䴌ËÅÒ¡ËÅÒ »˜¨¨Ñ 䴌ᡋ »˜¨¨Ñ·ҧ´ŒÒ¹¾Ñ¹¸Ø¡ÃÃÁ ¾ÄμÔ¡ÃÃÁ ÊÀÒ¾áÇ´ÅŒÍÁ áÅÐÇѲ¹¸ÃÃÁ7 ÁÕ¡ÒÃÈÖ¡ÉÒ¡‹Í¹Ë¹ŒÒ¹Õé·Õè ÃкØäÇŒÇ‹Ò âä͌ǹ໚¹âä·Õèà¡Ô´¨Ò¡¡Òö‹Ò·ʹ·Ò§¾Ñ¹¸Ø¡ÃÃÁ áÅÐâä ͌ǹ·Õèà¡Ô´¢Öé¹ã¹¡ÅØ‹Áà´ç¡ÁÑ¡ÁÕÍÔ·¸Ô¾Å ÁÒ¨Ò¡»˜¨¨Ñ·ҧ¾Ñ¹¸Ø ¡ÃÃÁÁÒ¡¶Ö§ÃŒÍÂÅÐ 30-708 â´Â·ÑèÇ仡ÒÃÈÖ¡ÉÒ·Ò§´ŒÒ¹¾Ñ¹¸ØÈÒÊμÏ Ê‹ Ç ¹ãËÞ‹ · Ó¡ÒÃÈÖ ¡ ÉÒà¾×è Í ÇÔ à ¤ÃÒÐˏ Ë Ò¡ÒÃ

à»ÅÕè¹á»Å§ËÃ×Í¡ÒáÅÒ¾ѹ¸Ø¢Í§ genomic DNA ¤ÇÒÁ ËÅÒ¡ËÅÒ¢ͧÂÕ¹μ‹Ò§ æ ËÃ×ͺÃÔàdzã¡ÅŒà¤Õ§ÂÕ¹ (genetic polymorphism ËÃ×Í single nucleotide polymorphism (SNPs) ËÃ×Í CA repeat microsatellites)9 ´Ñ§¹Ñé¹ ¨Ö§àËç¹ä´Œ Ç‹Ò»˜¨¨Ñ·ҧ´ŒÒ¹¾Ñ¹¸Ø¡ÃÃÁÁÕ¤ÇÒÁÊÓ¤ÑÞμ‹Í¡ÒÃà¡Ô´âä͌ǹ â´Ââä͌ǹ·Õèà¡Ô´¢Öé¹ÍÒ¨à¡Ô´¨Ò¡¡ÒáÅÒ¾ѹ¸Ø (mutation) ¢Í§ÂÕ¹à¾Õ§ÂÕ¹à´ÕÂÇ·ÕèàÃÕÂ¡Ç‹Ò “monogenic obesity” «Öè§ μÑÇÍ‹ҧ¢Í§ÂÕ¹ 䴌ᡋ ÂÕ¹ leptin (LEP), leptin receptor (LEPR), pro-opiomelanocortin (POMC), prohormone convertase 1 (PC1), melanocortin 4 áÅÐ 3 receptor â´Â¡ÒáÅÒ¾ѹ¸Øã¹ÂÕ¹´Ñ§¡Å‹ÒÇÁÕ¼Åú¡Ç¹¡Ò÷ӧҹ¢Í§ ÊÁͧʋǹäÎâ»·ÒÅÒÁÑÊ·ÕèÁÕ˹ŒÒ·Õè¤Çº¤ØÁ¤ÇÒÁËÔÇáÅФÇÒÁÍÔèÁ àÁ×èÍÂÕ¹àËÅ‹Ò¹ÕéÁÕÅӴѺ¹ÔǤÅÕâÍä·´·Õèà»ÅÕè¹á»Å§ä»ËÃ×Íà¡Ô´¡Òà ¡ÅÒÂ¾Ñ ¹ ¸Ø ¨ÐÁÕ ¼ Åμ‹ Í ¡Ò÷ӧҹ¢Í§ÂÕ ¹ ãËŒ ¼Ô ´ »¡μÔ ä»´Œ Ç Â áÅÐÊ‹ § ¼Åμ‹ Í ¡ÒÃáÊ´§ÍÍ¡¢Í§ÅÑ ¡ ɳÐÀÒ¹͡ (phenotype) ·ÕèÁÕ¤ÇÒÁà¡ÕèÂÇ¢ŒÍ§¡Ñº¾ÄμÔ¡ÃÃÁ¡ÒáԹ áÅÐÍÒ¨ ¾Ñ²¹Ò¨¹¡ÅÒÂ໚¹âä͌ǹ·ÕèÃعáçÁÒ¡¢Öé¹μÑé§áμ‹ÇÑÂà´ç¡10 ÂÕ¹ leptin àÃÕ¡໚¹ÀÒÉÒä·ÂÇ‹Ò “àÅ»·Ô¹” μÑé§ÍÂÙ‹º¹ â¤ÃâÁâ«Á¤Ù‹·Õè 7 μÓá˹‹§ q31.3 »ÃСͺ´ŒÇ 3 àÍ硫͹ (exon)11 ¡Ò÷ӧҹ¢Í§ÂÕ¹àÅ»·Ô¹ÁÕ¼Åμ‹Í¡ÒÃÊÌҧÎÍÏâÁ¹àÅ»·Ô¹12 «Öè §â»ÃμÕ ¹ ¹Õé ¶Ù ¡ ¼ÅÔ μ ¢Öé ¹ ¨Ò¡à¹×é Í àÂ×è Í ÊÐÊÁä¢ÁÑ ¹ ¢Í§Ã‹ Ò §¡Ò 13 ÎÍÏ â Á¹àÅ»·Ô ¹ ໚ ¹ ÊÒàËμØ ·Õè · ÓãËŒ à ¡Ô ´âä͌ Ç ¹Í‹ Ò §ÃØ ¹ áç à¹×èͧ¨Ò¡ÁÕ¤ÇÒÁÊÓ¤ÑÞμ‹Í¡ÒÃÊ‹§ÊÑÞÞÒ³»ÃÐÊÒ··Õè·ÓãËŒÁ¹Øɏ ÃÙŒÊÖ¡ÍÔèÁ «Öè§Ê‹§¼Åμ‹Í¡ÒÃÊÐÊÁ¢Í§ä¢Áѹã¹Ã‹Ò§¡ÒÂáÅйéÓ˹ѡμÑÇ ÎÍÏ â Á¹àÅ»·Ô ¹ ·Ó§Ò¹â´Âä»Å´¡ÒÃ¡Ô ¹ ÍÒËÒÃáÅÐà¾Ôè Á ¡Òà à¼Ò¼ÅÒÞ¾Åѧ§Ò¹ã¹Ã‹Ò§¡ÒÂ14 ÁÕ¡ÒÃÈÖ¡ÉÒ¾ºÇ‹Ò¡ÒáÅÒ¾ѹ¸Ø ¢Í§ÂÕ¹àÅ»·Ô¹à»š¹ÊÒàËμØ·Õè·ÓãËŒà¡Ô´âä͌ǹáÅÐâäàºÒËÇÒ¹ ã¹Ë¹Ù·´Åͧ áÅÐÂѧʋ§¼Å¶Ö§¡ÒÃà¡Ô´ÀÒÇÐμ‹Ò§ æ ã¹Á¹Øɏ ÍÕ¡´ŒÇ ઋ¹ ÀÒÇСÒáԹÍÒËÒÃÁÒ¡¡Ç‹Ò»¡μÔ (hyperphagia) ÀÒÇзÕèËҧ¡ÒÂäÁ‹ÊÒÁÒöà¼Ò¼ÅÒÞ¾Åѧ§Ò¹ËÃ×Íà¼Ò¼ÅÒÞä´Œ àÅ硹ŒÍ (hypothermia) ໚¹μŒ¹15 ¶Ö§áÁŒÇ‹Ò¡ÒáÅÒ¾ѹ¸Ø¢Í§ ÂÕ¹àÅ»·Ô¹¾ºä´ŒäÁ‹ÁÒ¡¹Ñ¡ áμ‹¡ÒÃÈÖ¡ÉÒ¡‹Í¹Ë¹ŒÒ¹Õé ä´ŒáÊ´§ ãËŒàË繶֧¤ÇÒÁÊÓ¤ÑޢͧÂÕ¹àÅ»·Ô¹·ÕèÁÕμ‹Í¡ÒäǺ¤ØÁÊÁ´ØÅ ¾Åѧ§Ò¹¢Í§Á¹Øɏ16 ´Ñ§¹Ñé¹ àÁ×èÍÂÕ¹àÅ»·Ô¹¼Ô´»¡μÔ仨зÓãËŒ Ëҧ¡ÒÂËÅÑè§ÎÍÏâÁ¹àÅ»·Ô¹à»ÅÕè¹á»Å§ä»´ŒÇ ʋ§¼ÅãËŒÁ¹Øɏ äÁ‹ÃÙŒÊÖ¡ÍÔèÁ¨Ö§¡Ô¹ÍÒËÒÃà¾ÔèÁ¢Öé¹ Ã‹Ò§¡ÒÂà¼Ò¼ÅÒÞ¾Åѧ§Ò¹ä´Œ¹ŒÍ ·ÓãËŒä¢ÁѹÁÕ¡ÒÃÊÐÊÁμÒÁËҧ¡Ò áÅÐà¡Ô´âä͌ǹ·ÕèÃعáç μÒÁÁÒ Í‹ҧäáçμÒÁ áÁŒ¾ºà¾Õ§¡ÒÃà»ÅÕè¹á»Å§ÅӴѺ¹ÔǤÅÕ âÍä·´¢Í§ÂÕ¹àÅ»·Ô¹ áÅкÃÔàdzã¡ÅŒà¤Õ§ÂÕ¹ (SNPs) áμ‹¾ºÇ‹Ò ÁÕ ¤ ÇÒÁÊÑ Á ¾Ñ ¹ ¸ ¡Ñ ºâä͌ Ç ¹ËÃ× Í ¡ÒÃáÊ´§ÍÍ¡¢Í§ÅÑ ¡ ɳРÀÒ¹͡㹤¹ÍŒ Ç ¹ «Öè § μÓá˹‹ § ·Õè Í ÂÙ‹ Ê‹ Ç ¹Ë¹Œ Ò ¢Í§ÂÕ ¹ ËÃ× Í ·Õè ªï∑’Ë 43 ©∫—∫∑’Ë 4 μÿ≈“§¡ - ∏—𫓧¡ 2551

R1_Nutrition_p14-16_pro1.indd Sec1:15

15

6/22/09 10:42:59 PM


àÃÕ Â ¡Ç‹ Òâ»ÃâÁàμÍÏ (promoter) ¢Í§ÂÕ ¹ àÅ»·Ô ¹ ÁÕ ¼ Åμ‹ Í ¡Ò÷ӧҹ¢Í§à¹×é Í àÂ×è Í ÊÐÊÁä¢ÁÑ ¹ ´ŒÇÂ17 ´Ñ§¹Ñé¹ ¤ÇÒÁÃÙŒà¡ÕèÂǡѺ¡ÒáÅÒ¾ѹ¸ØËÃ×Í¡ÒÃà»ÅÕè¹á»Å§¢Í§ÅӴѺ¹ÔǤÅÕâÍä·´ã¹ÂÕ¹àÅ»·Ô¹ áÅкÃÔàdzã¡ÅŒà¤Õ§ ¨Ö§ÁÕ¤ÇÒÁÊÓ¤ÑÞμ‹Í¡ÒÃÈÖ¡ÉÒ¡ÒÃà¡Ô´âä͌ǹã¹Á¹Øɏ 12 ¡ÒÃμÃǨËÒ ¾Ñ¹¸Ø¡ÃÃÁ¨Ò¡μÑÇÍ‹ҧàÅ×Í´ à¾×èÍËÒ¡ÒáÅÒ¾ѹ¸ØËÃ×Í¡ÒÃà»ÅÕè¹á»Å§¢Í§ÂÕ¹àÅ»·Ô¹¨Ö§ÁÕ»ÃÐ⪹ ໚ ¹ Í‹ Ò §ÂÔè § à¾ÃÒÐ໚ ¹ ¡ÒäŒ ¹ ËÒÊÒàËμØ ¢ ͧ¡ÒÃà¡Ô ´âä͌ Ç ¹ã¹ÃÐ´Ñ ºâÁàÅ¡Ø Å àÁ×è Í ·ÃҺNj Ò ÁÕ ¡ÒüԴ»¡μԢͧÂÕ¹àÅ»·Ô¹áÅŒÇ μŒÍ§¤Çº¤ØÁ¹éÓ˹ѡμÑÇáÅÐÃÐÁÑ´ÃÐÇѧμ¹àͧ໚¹¾ÔàÈÉ à¾×èÍ»‡Í§¡Ñ¹ ¡ÒÃà¡Ô´âäÍ×è¹ æ ·Õè໚¹¼ÅÁÒ¨Ò¡âä͌ǹ䴌¡‹Í¹·Õè¨ÐÊÒÂà¡Ô¹ä» àÍ¡ÊÒÃ͌ҧÍÔ§

1. Saris W. Overweight and obesity in European children and adolescents: causes and consequences prevention and treatment. Eur J Pediatr. 2000;159(13):1-68. 2. Frye C, Heinrich J. Trends and predictors of overweight and obesity in East German children. Int J Obes Relat Metab Disord. 2003;27(8):963-9. 3. American Diabetes Association. Type II diabetes in children and adolescents [cited 2008 August 30]. Available from: http://pediatrics.aappublications.org/cgi/reprint/105/3/671.pdf. 4. Kantachuvessiri A. Obesity in Thailand. J Med Assoc Thai. 2005;88(4):554-62. 5. The prevalence of over nutrition status in Thai children [cited 2008 August 22]. Available from: http://nutrition.anamai.moph.go.th/fatboy.htm 6. Jirapinyo P, Densupsoontorn N, Chinrungrueng D, Wongarn R, Thamonsiri N. Relative risks of becoming overweight and obese in children after 6 years in secondary school. J Med AssocThai. 2005;88(5):651-4. 7. Krassas GE, Tzotzas T. Do obese children become obese adults: childhood predictors of adult disease. Pediatr Endocrinol Rev. 2004;1 Suppl 3:455-9. 8. Bouchard C. Current understanding of the etiology of obesity: genetic and non-genetic factors. Am J Clin Nutr. 1991;52:1561S-5S. 9. Clement K. Genetics of human obesity. C R Biol. 2006;329(8):608-22. 10. Hainerova I. Obesity based on mutation of genes involved in energy balance. Cas Lek Cesk. 2007;146(3):240-5. 11. Tatti P, Masselli L, Buonanno A, Di Mauro P, Strollo F. Leptin levels in diabetic and nondiabetic subjects. Endocrine. 2001;15(3):305-8. 12. Paracchini V, Pedotti P, Taioli E. Genetics of leptin and obesity: a HuGE review. Am J Epidemiol. 2005;162(2):101-14. 13. Trayhurn P, Beattie JH. Physiological role of adipose tissue: white adipose tissue as an endocrine and secretory organ. Proc Nutr Soc. 2001;60:329-39. 14. Baratta M. Leptin from a signal of adiposity to a hormonal mediator in peripheral tissues. Med Sci Monit. 2002;8(12):RA282-92. 15. Chen D, Garg A. Monogenic disorders of obesity and body fat distribution. J Lipid Res 1999;40(10):1735-46. 16. Froguel P, Boutin P. Genetics of pathways regulating body weight in the development of obesity in humans. Exp Biol Med (Maywood). 2001;226(11):991-6. 17. Miller SG, De Vos P, Guerre-Millo M, Wong K, Hermann T, Staels B, et al. The adipocyte specific transcription factor C/EBPalpha modulates human ob gene expression. Proc Natl Acad Sci U S A. 1996;93(11):5507-11. 16

«“√ “√‚¿™π“°“√

R1_Nutrition_p14-16_pro1.indd Sec1:16

6/22/09 10:42:59 PM


Nutrition

Research

ÃÔÞ à¨ÃÔÞÈÔÃÔ1 Rin Charoensiri4 1 ª¹ÔÅà¹μà μ‹ÍÊËСØÅ Chaninneat Torsahakul4 ÃѪ¹Õ ¤§¤Ò©Ø©ÒÂ2, 3 Ratchanee Kongkachuichai1, 4

ª√‘¡“≥‡°≈◊Õ·√à™π‘¥μà“ßÊ ‚æ≈’øïπÕ≈ ·∑ππ‘π ·≈–‰ø‡μ∑„πº≈‰¡â‰∑¬ Macro-mineral, polyphenol, tannin, and phytate contents in Thai fruits

1 2 3 4

¹Ñ¡ÇԨѠ½†ÒÂà¤ÁÕ·Ò§ÍÒËÒà ʶҺѹÇÔ¨ÑÂâÀª¹Ò¡Òà ÁËÒÇÔ·ÂÒÅÑÂÁËÔ´Å ÈÒÅÒÂÒ ¾Ø·¸Á³±Å ¨.¹¤Ã»°Á 73170 ¼ÙŒª‹ÇÂÈÒÊμÃÒ¨ÒÏ ´Ã. ½†ÒÂà¤ÁÕ·Ò§ÍÒËÒà ʶҺѹÇÔ¨ÑÂâÀª¹Ò¡Òà ÁËÒÇÔ·ÂÒÅÑÂÁËÔ´Å ÈÒÅÒÂÒ ¾Ø·¸Á³±Å ¨.¹¤Ã»°Á 73170 Correspondence; e-mail: nurkk@mahidol.ac.th Food chemistry division, Institute of nutrition, Mahidol university, Salaya, Phuthamonthon, Nakhon-pathom 73170.

ªï∑’Ë 43 ©∫—∫∑’Ë 4 μÿ≈“§¡ - ∏—𫓧¡ 2551

R1_Nutrition_p17-27_pro1.indd Sec1:17

17

6/22/09 10:53:01 PM


∫∑§—¥¬àÕ

¡ÒÃÈÖ¡ÉÒ¤ÃÑ駹Õéä´Œ·Ó¡ÒÃÇÔà¤ÃÒÐˏËÒ»ÃÔÁÒ³á˸Òμت¹Ô´μ‹Ò§æ 䴌ᡋ â«à´ÕÂÁ â¾á·Êà«ÕÂÁ áÅÐ áÁ¡¹Õà«ÕÂÁ ÃÇÁ·Ñé§â¾ÅÕ¿‚¹ÍÅ á·¹¹Ô¹ áÅÐä¿àμ·ã¹¼ÅäÁŒÊ´ 37 ª¹Ô´ «Öè§ÁÒ¨Ò¡μÅÒ´ 6 áË‹§ ã¹à¢μ¡Ãا෾ÁËÒ¹¤Ã ¼Å¡ÒÃÈÖ¡ÉÒ¾ºÇ‹Ò¼ÅäÁŒÁÕ»ÃÔÁÒ³â¾á·Êà«ÕÂÁÁÒ¡·ÕèÊØ´ μÑé§áμ‹ 29 - 406 ÁÔÅÅÔ¡ÃÑÁμ‹Í 100 ¡ÃÑÁ â´Â¾ºÁÒ¡·ÕèÊØ´ã¹·ØàÃÕ¹ªÐ¹Õ (Durio zibethinus) ÃͧŧÁÒ ¤×Í ¡ÅŒÇÂËÍÁ áÅСŌÇÂ䢋 (Musa sapientum) ÁÕ 347 áÅÐ 310 ÁÔÅÅÔ¡ÃÑÁμ‹Í 100 ¡ÃÑÁ μÒÁÅӴѺ ʋǹâ«à´ÕÂÁáÅÐáÁ¡¹Õà«ÕÂÁÁÕ»ÃÔÁÒ³μÑé§áμ‹ 0.6 - 16 áÅÐ 4 - 25 ÁÔÅÅÔ¡ÃÑÁμ‹Í 100 ¡ÃÑÁ â¾ÅÕ¿‚¹ÍÅáÅÐá·¹¹Ô¹ÁÕ»ÃÔÁÒ³μÑé§áμ‹ 4.7 - 322.6 ÁÔÅÅÔ¡ÃÑÁ¡ÒÅÔ¤áÍ«Ô´ÍÔ¤ÇÔÇÐàŹ· áÅÐ 0.6 - 43.4 ÁÔÅÅÔ¡ÃÑÁá·¹¹Ô¤áÍ«Ô´ÍÔ¤ÇÔÇÐàŹ· μÒÁÅӴѺ â´Â¹ŒÍÂ˹‹Ò˹ѧ (Annona squamosa L.) ÁÕâ¾ÅÕ¿‚¹ÍÅáÅÐá·¹¹Ô¹ÁÒ¡·ÕèÊØ´ (322.6 ÁÔÅÅÔ¡ÃÑÁ¡ÒÅÔ¤áÍ«Ô´ÍÔ¤ÇÔÇÐàŹ· áÅÐ 43.4 ÁÔÅÅÔ¡ÃÑÁ á·¹¹Ô¤áÍ«Ô´ÍÔ¤ÇÔÇÐàŹ· μÒÁÅӴѺ) ʋǹä¿àμ·ÁÕ»ÃÔÁÒ³μÑé§áμ‹äÁ‹¾º ¨¹¶Ö§ 6.0 ÁÔÅÅÔ¡ÃÑÁμ‹Í 100 ¡ÃÑÁ ã¹á¡ŒÇÁѧ¡Ã (Hylocereus undatus Britt.) ¡Å‹ÒÇ䴌NjҼÅäÁŒä·ÂÁÕ»ÃÔÁÒ³â«à´ÕÂÁáÅÐ áÁ¡¹Õà«ÕÂÁàÅ硹ŒÍ áμ‹à»š¹áËÅ‹§·Õè´Õ¢Í§â¾á·Êà«ÕÂÁáÅÐâ¾ÅÕ¿‚¹ÍÅ ¤ÓÊÓ¤ÑÞ : á˸ÒμØ â¾ÅÕ¿‚¹ÍÅ ä¿àμ· ¼ÅäÁŒ

18

«“√ “√‚¿™π“°“√

R1_Nutrition_p17-27_pro1.indd Sec1:18

6/22/09 10:53:01 PM


Abstract

A total of 37 varieties of fresh fruits obtained from six markets in Bangkok, Thailand were determined for macro-mineral (sodium, potassium, and magnesium), total polyphenol, tannin, and phytate contents. Potassium content was the highest ranging from 29 up to 406 mg/100 g of wet weight: greatest in durian, Durio zibethinus (“chanee”), followed by ripe banana, Musa sapientum (“hawm” and “kai”) (347 and 310 mg/100 g of wet weight. Sodium and magnesium contents ranged from 0.6 to 16 and 4 to 25 mg/100 g of wet weight, respectively. Total polyphenol and tannin contents ranged from 4.7 to 322.6 mg gallic acid equivalent (GAE) and 0.6 to 43.4 mg tannic acid equivalent per 100 g of wet weight, respectively. Sugar apple; Annona squamosa L. (“nahng”), had the highest amount of total polyphenol and tannin contents (322.6 GAE and 43.4 mg tannic acid equivalent/100 g, respectively). Phytate content ranged from undetectable to 6.0 mg/100 g of wet weight in dragon fruit; Hylocereus undatus Britt. Thus Thai fruits provided small amounts of sodium and magnesium but were good sources of potassium and polyphenols. Keywords : Macro-minerals, polyphenol, phytate, fruits

ªï∑’Ë 43 ©∫—∫∑’Ë 4 μÿ≈“§¡ - ∏—𫓧¡ 2551

R1_Nutrition_p17-27_pro1.indd Sec1:19

19

6/22/09 10:53:01 PM


Introduction

Among 58 million mortality in the world in 2005, non-communicable diseases (NCDs), viz. cardiovascular diseases, cancer, chronic respiratory diseases, diabetes, kidney diseases and other chronic diseases, were estimated to account for 35 million (61%), 80% of which occur in developing countries1. WHO has predicted that mortality due to NCDs will increase from 61% in 2005 to 68% in 20301. Data from the National Health and Nutrition Examination Surveys III (NHNES III) indicated that the prevalence of hypertension (HT) in U.S. adults increased from 24% during 1988-1991 to 28.7% during 1999-20002. The prevalence and mortality rate of HT in Thailand have increased every year3. Furthermore, the prevalence of chronic kidney disease (CKD) has been reported in many countries. In USA, the Third National Health and Nutrition Examination Survey (NHANES III) showed that 11% (19.2 millions) of the population were diagnosed with CKD4. CKD prevalence in the western part of Australia was 16% and in Singapore CKD prevalence of 10.1% was reported 5,6. In Thailand, the Thailand Renal Replacement Therapy (TRT) registry estimated that the prevalence of end stage renal diseases (ESRD) was 1,995 cases in 2000 and would increase to 13,597 cases in 20047. Thailand is one of the developing countries whose economic structure has shifted from agriculture to industry and commercial activities. Social structure and lifestyle have accordingly changed from a rural to an urban society. Eating patterns have shifted from a traditional Asian diet, e.g. high consumption of cereals, fruits and vegetables, and low fat, to a Westernized diet, e.g. high consumption of animal products, fats and sugars, and low consumption of fruits and vegetables. Various investigators have pointed out that lifestyle and eating patterns are important factors contributing to the increased prevalence of NCDs, chronic diseases, and diet-related diseases8-10. Fruits are a major part of the daily 20

consumption for both healthy people and patients and have a variety of pleasant and attractive flavors. Fruits contain substances or constituents such as vitamins, minerals, phyto-nutrient with strong antioxidant capacity, viz. polyphenol, tannin, and phytate which are highly beneficial to human health and also contribute to the prevention of NCDs11-14. Several studies revealed that high fruits and vegetables consumption can promote health and reduce a risk factor of non-communicable diseases and chronic diseases8-10. The nutritional values of Thai fruits have not been completely evaluated and some data were taken from fruits in other countries15. Thus some of the data used for calculations of the nutritive values may deviate from the actual values. Furthermore, the data of nutritive values are out of date. Accurate and current data provide important information for physicians, dieticians, public health workers, and the general consumers and are essential for patients with hypertension, coronary heart diseases and renal diseases where proper selection of food is required. Thus the objective in this study was to determine mineral [sodium (Na), potassium (K), magnesium (Mg)], polyphenol, tannin, and phytate (myo-inositol phosphates penta and hexaphosphates) contents in selected Thai fruits. Materials and methods

Sample collection

Fresh fruit samples were obtained from six markets in Bangkok, Thailand. At each market, 2.0-3.0 kg of each kind of fruit sample was sampled from three different outlets. A single composite sample was prepared by combining about 600 g of a homogenized single sample of the same variety from the three sources and homogenizing again to obtain a uniform single composite sample from a single market. Information of fresh fruits commonly consumed in Thailand is shown in Table 1.

«“√ “√‚¿™π“°“√

R1_Nutrition_p17-27_pro1.indd Sec1:20

6/22/09 10:53:01 PM


Table 1

Names, moisture content, serving amount, and mineral, polyphenol, tannin, and phytate contents of Thai fruits

Common English name

Thai name

Apple Fuji variety (not peeled) Granny Smith variety (peeled)

Apple-fu-ji Apple-khiaw

Banana Hawm variety Kai variety Nahmwah variety

Glooway-hawm Glooway-kai Glooway-nahm-wah

Chinese pear Home variety (not peeled) Salee-hom Namphung variety (peeled) Salee-namphung

Scientific name Pyrus malus L.

Moisture One Na3 K3 Mg3 Polyhenol4 Tannin5 Phytate6 contents1 serving2 (%) (g) 85.1 + 2.3 86.0 + 1.1

102 100

2 29 4 2 30 4

24.4 90.2

2.2 1.8

1.5 1.7

75.5 + 1.6 71.6 + 1.8 67.1 + 1.9

53 48 53

4 347 22 7 310 23 5 204 25

90.4 93.5 96.0

2.2 5.2 13.4

0.1 0.4 0.4

85.4 + 0.6 86.2 + 0.9

136 135

5 41 7 4 51 6

29.8 14.6

4.7 1.8

0.8 0.9

Hylocereus undatus Britt. 85.0 + 0.7

120

4 271 23

64.0

2.0

6.0

66.8 + 3.8 70.9 + 4.4

58 50

4 406 16 2 292 20

115.5 176.6

5.3 4.9

ND ND

Musa sapientum L.

Pyrus communic L.

Dragon fruit Vietnam variety

Gaew-muang-gorn

Durian (ripe) Chanee variety Mawntong variety

Thurian-chanee Thurian-mawntong

Grape Green variety

A-ongn

Vitis vinifera L.

82.6 + 2.6

93

6 125 5

77.5

6.3

0.6

Guava Panseetong variety

Farang

Psidium guajava L.

87.5 + 1.4

123

6 210 6

107.8

7.1

2.5

Jackfruit

Khanun

74.1 + 1.8

61

5 207 19

47.2

0.8

1.2

Longan Kalokbew variety

Artocarpus heterophylla Lalm.

Lamyai-kalokbew

Euphoria longana Lam. 79.8 + 0.8

86

11 105 8

100.0

5.5

0.1

Longkong

Long-gong

Lansium domesticum Corr. 80.6 + 0.4

94

3 192 12

36.7

0.9

3.2

Lychee Hohnghooway variety Jackkrapat variety

Linchi-honghouy Linchi-Jackkrapat

81.3 + 0.7 82.5 + 1.0

98 78

3 131 10 3 165 9

111.8 117.4

5.9 12.9

1.9 4.3

79.3 + 1.7 80.1 + 1.9 82.4 + 1.8

75 79 76

0.6 90 9 3 81 9 4 105 7

65.2 79.2 81.5

15.4 32.4 13.8

0.3 0.1 1.2

Garcinia mangostana L. 80.2 + 1.3

77

2 32 12

86.9

1.2

0.3

87.6 + 1.7 85.9 + 1.2

101 122

2 84 9 5 229 7

61.2 67.1

1.3 0.7

0.7 0.8

Durio zibethinus

Litchi chinensis Conn.

Mangifera indica L. Mango Kheosawoei variety (unripe) Mamuang-kheosawoei Nahmdawgmai variety (ripe) Mamuang-nahmdawgmai Mamuang-rad Rad variety (unripe) Mangosteen

Mang-khut

Orange Clementine variety Sainuhmphung variety

Som-cheang Citrus sinensis Osb. Somsai-nahmphung Citrus reticulata

ªï∑’Ë 43 ©∫—∫∑’Ë 4 μÿ≈“§¡ - ∏—𫓧¡ 2551

R1_Nutrition_p17-27_pro1.indd Sec1:21

21

6/22/09 10:53:01 PM


Table 1

Names, moisture content, serving amount, and mineral, polyphenol, tannin, and phytate contents of Thai fruits (Continue)

Common English name

Thai name

Scientific name

Moisture One Na3 K3 Mg3 Polyhenol4 Tannin5 Phytate6 contents1 serving2 (%) (g)

Papaya (ripe) Sriracha variety

Malagor-khakdahm

Carica papaya L.

89.5 + 0.7

130

3 199 7

4.7

1.5

ND

Pineapple Sriracha varitety

Sapparot-sriracha

Ananas comosus Merr. 84.9 + 1.0

101

4 61 10

50.3

0.7

ND

Pomelo Khaonahmpeung variety Tongdee variety

Som-o-Khaonahmpeung Som-o-Tongdee

88.2 + 2.0 88.7 + 0.6

92 125

8 80 5 8 92 6

37.9 32.6

0.6 0.6

0.8 2.0

Rambutan Rongrean variety

Ngor-rohngrain

Nephelium lappaceum L. 80.8 + 2.8

75

3 78 10

67.4

2.9

2.0

Rose apple Toonklow variety Tuptimjun variety

Chomphu-toolgaow Chomphu-tuptimjun

91.0 + 1.4 89.0 + 0.6

205 152

4 62 6 6 106 7

24.3 19.7

3.9 3.5

ND 0.1

Salacca

Sala

Salacca zalacca

80.1 + 0.4

78

6 115 8

71.3

2.1

ND

Sapodilla (peeled)

Lamut

Achras sapota L.

75.5 + 1.1

69

16 128 10

57.6

26.3

1.5

Star fruit Malaysia variety

Mafuong

Averrhoa carambola L. 89.2 + 0.4

159

3 74 7

148.4

9.2

0.3

Strawberry

Strawberry

Fragaria x ananassa

89.6 + 2.5

180

3 132 10

220.6

15.8

2.2

Sugar apple Nahng variety

Noina-nahng

Annona squamosa L. 74.1 + 1.6

57

0.8 214 21

322.6

43.4

ND

Watermelon Jin-trarah variety (red color) Jin-trarah variety (yellow color)

Taeng mo-Jintrarah (red color) Taeng mo-Jintrarah (yellow color)

Citrullus vulgaris Schrd. 88.8 + 2.0

170

5 120 9

28.2

0.9

ND

91.5 + 1.3

188

3 111 8

23.4

6.2

0.2

1 2

3 4 5 6

22

Citrus maxima Meer.

Syzygium samarangense Merr.

Value is mean + SD (g/100 g) of duplicate analysis (n = 6) One edible portion (serving) of each fresh fruit (gram) is based on the food exchange list that provides 15 g of carbohydrate37 and then the weight of one edible portion is calculated by using the amount of carbohydrate of each kind of fruit from Food Composition Table, institute of Nutrition Mahidol University15 Data are reported in a mean (mg/100 g edible portion) of duplicte analysis (n = 6) Expressed as mg GAE equivalent per 100 g of wet weight Expressed as mg tannic acid equivalents per 100 g of wet weight Sum of penta (IP5) and hexaphosphates (IP6) and reported in mg/100 g of wet weight

«“√ “√‚¿™π“°“√

R1_Nutrition_p17-27_pro1.indd Sec1:22

6/22/09 10:53:01 PM


Sample preparation

Before preparation, all samples were rinsed with tap water several times to ensure that all contaminants were removed and then rinsed again with deionized water. Fruit samples were then individually prepared using common household practice. The edible portions of each single sample were separated and homogenized in an electric blender (Cucina HR1791/6, Philips, Bangkok, Thailand). Homogenized samples were divided into 2 portions, one portion used as the fresh sample for Na, K and Mg determination and the other portion as the freeze dried sample (Hetosicc model PL 9000-50, Birkerod, Denmark) for investigating total polyphenols, tannin, and phytate. Mineral analysis

Samples were ashed in a muffle furnace at 550 íC and ash solutions were prepared by dry ashing. Fruit mineral analysis for Na, K and Mg was performed using inductively coupled plasma-atomic emission spectrometry (ICP-AES, PerkinElmer Optima 4200 DV, Waltham, Massachusetts, USA) according to AOAC, 200516. Determination of polyphenol content

Concentrations of total polyphenols were determined using Folin-Ciocalteu method 17 . Absorbance measurements at 750 nm were performed in a spectrophotometer (Spectronic Unicam He ios Alpha & Beta, Helios Alpha, Helios Beta, UV1, Cambridge, UK) using gallic acid (GA) as a standard. Results were expressed as mg GA equivalent (GAE) per 100 g of wet weight. Determination of tannin content

Tannin content was determined by extracting with 50% dimethylformamide in acetate buffer and measuring absorbance at 578 and 680 nm17,18. The results were expressed as mg tannic acid equivalent per 100 g of wet weight

Determination of phytate content

Inositol pentaphosphate (IP5) and inositol hexaphosphate (IP6) contents were determined according to the methods of Hotz & Gibson, 2001 19. In brief, approximately 0.5 g of the lyophilized sample was extracted with 5 mL of 0.67 M HCl for 30 min in an ultrasonic bath (Bransonic, model 1510E-MT, Alabama, Mississippi, USA). Following centrifugation at 3,000 rpm for 10 min (Hima centrifuge CR5B2, Hitachi, Tokyo, Japan), 2.5 mL of supernatant were removed and diluted with 22.5 mL of deionized water. The solution was then applied onto an anion-exchange column (WAT023620, Sep-Pak Vac 1 cm3 Water Accell Plus QMA, Water, Milford, MA) and inositol phosphates was eluted with 4 mL of 2 M HCl and evaporated to dryness at 40 íC in a centrifugal evaporator (Eyela, Model CVE-2000, Tokyo, Japan). The residue was then dissolved in 1 mL of deionized water and analysis of IP5 and IP6 was performed by ion-pair reverse phase chromatography (Alliance, Water IR 2414, Milford, Massachusetts, USA) using a C18 column (Atlantis dC18, 5 x m, 4.6 x 150 mm2, Milford, Massachusetts, USA) and a mobile phase of methanol:H2O (3:2) at a flow rate of 0.8 mL/min at 40 íC. Eluted inositol phosphates were detected using a refractive index detector (Waters IR2414). Quality control

In each set of the analysis, simultaneous analysis of in-house reference material (black rice flour) for phytate, polyphenol, and tannin was performed while soybean flour was used as an inhouse reference material for daily control samples of mineral analysis. Statistical Analysis

Determinations of minerals, polyphenols, tannin, and phytate were reported as mean values (mean + SD). The nutritive values were classified as low, ªï∑’Ë 43 ©∫—∫∑’Ë 4 μÿ≈“§¡ - ∏—𫓧¡ 2551

R1_Nutrition_p17-27_pro1.indd Sec1:23

23

6/22/09 10:53:01 PM


medium and high levels using quartile deviation. SPSS for Window version 13 software program (SPSS Inc, Chicago, Illinois, USA) was employed in all computations. Results and discussion

Mineral content

The macro-mineral (Na, K and Mg) contents of 37 Thai fruit varieties are presented in Table 1. Sodium content ranged from 0.6 to 16 mg/100 g of wet weight. According to quartile deviation, the concentrations of Na in Thai fruits samples could be divided into three levels: high (6 mg/100 g), medium (3 to 6 mg/100 g) and low (3 mg/100 g). Longan (“kalok-bew”) and sapodilla contained the greatest amount of Na (11 and 16 mg/100 g, respectively), but they provided only 0.5% Thai Na RDI (2,400 mg/day, Ministry of Public, 2003)20. The mean concentrations of Na among fresh fruits determined in this study were lower than those obtained from 1999 Thai food composition table15, but values for ripe banana (“nahm-wah”), ripe mango (“nahmdawgmai”), rambutan (“rong-rean”), and watermelon (red color “jin-trarah”) were in agreement with those obtained previously. Na contents of durian (“mawntong”), grape (green variety), lychee (“jackkrapat”), unripe mango (“kheosawoei”), orange (clementine), ripe papaya (“khak-dahm”) and sapodilla in this study were lower than the values of Kongkachuichai 199021, except that of longan (“kalok-bew”) that showed a higher content. Sodium contents of guava, ripe mango (“nahmdawgmai”) unripe mango (“rad”), longan (“kalok-bew”), ripe papaya (“khak-dahm”), pineapple (“sriracha”), rambutan, and star fruit were similar to those of the same varieties in previous studies by Leterme et al., 2006, Wall, 2006, Hardisson et al., 2001, Puwastien, et al., 1999 and Sanchez-Castillo, et al., 199815,22-25. However, values for ripe banana, papaya and rambutan in the 24

previous studies showed higher values (5-21, 7-24 and 6 mg/100 g, respectively) than those in the present study. Potassium content presented the greatest amount in the majority of fresh fruits, ranging from 29 to 406 mg/100 g of wet weight According to quartile deviation, K content could be classified based on high (201 mg/100 g), medium (75 to 201 mg/100 g) and low (75 mg/100 g) levels. Ripe banana and durian (“chanee”) had the highest K amount (204-347 and 406 mg/100 g, respectively) while apple and mangosteen contained the lowest content. Potassium contents of fresh fruits determined in this study were similar to those previously reported by Leterme et al., 2006, Wall, 2006; Puwastien, et al., 1999 and Sanchez-Castillo et al., 199815,22,25,26. Ripe papaya (“khak-dham”) provided some variation in K content when compared with other previous reports, viz. 230 mg/ 100 g by Puwastien, et al., 199915, 194 mg/100 g by Sanchez-Castillo et al., 199825, 154 g/100 g by Wall, 200626, 85 mg/100 g by Leterme et al., 200622. Potassium content of ripe banana in this study was in agreement with the value reported by Wall, 2006 (330.6 mg/100 g)26, but not with that of Hardisson et al., 2001 (509 mg/100 g)24. On the other hand, when comparing our results with those obtained in other studies22,26, the mean concentrations of K in guava, longan, rambutan, mango, sugar apple and star fruit were lower. Based on our studies, consumption of one serving of dragon fruit, durian (“chanee”), guava, orange, papaya, and strawberry would meet 7-8% of the Thai RDI for K (3,500 mg/day, Ministry of Public, 2003)20. Magnesium contents in fresh fruit samples were similar to those of with Na, ranging from 4 to 25 mg/100 g of fresh sample. Quartile deviation divided Mg content into high (11 mg/100 g), medium (6 up to 11 mg/100 g) and low (6 mg/

«“√ “√‚¿™π“°“√

R1_Nutrition_p17-27_pro1.indd Sec1:24

6/22/09 10:53:01 PM


100 g) levels. Ripe banana (“nahm-wah”) contained more Mg (25 mg/100 g) than other fruits. The Daily Intake of Mg for Thai adults is 350 mg/day and thus fresh fruits can supply 1 up to 8% of the Thai RDI for Mg20. Consumption for one serving of ripe banana (53 g, “nahmwah”), rose apple (152 g, “toonklow”), strawberry (180 g), watermelon (170-188 g), and dragon fruit (120 g, Vietnam variety) would meet 4 to 8% of Thai RDI requirement. Variations of our results of the macro-mineral (Na, K and Mg) values with those of previous publications may be due to differences in agroclimatic conditions, variety, state of ripeness, soil type and fertilization, transportation26-29. Polyphenol, tannin, and phytate contents

Total polyphenol, tannin, and phytate contents in Thai fruits ranged from 4.7 to 322.6, 0.6 to 43.4 and not detectable to 6.0 mg/100 g of wet weight, respectively (Table 1). Sugar apple (“nahng”) contained the highest content of polyphenol and tannin, while the highest phytate content was found in dragon fruit (Vietnam variety). All fresh fruits, except ripe papaya (“khakdahm”) were shown to be excellent sources of total polyphenols. On the other hand, all fresh fruits were poor sources of tannin and phytate. A comparison of the results of non-nutrients (total polyphenols, tannin, and phytate) from this study with other previous publications revealed wide variations that may be attributed to such factors as cultivation, environment condition, region and weather conditions, soil, variety, degree of ripeness, fertilization, seasonal variation, stage of maturity, and difference in method of sampling and preparation 24,27,30,31 . At present, there is no information on the recommended intake level for total polyphenols, tannin, and phytate. Scalbert & Williamson, 200032 indicated that a normal intake

of total polyphenols should be around 1,000 mg GAE/day. Thus the consumption of only one serving of sugar apple (57 g) and strawberry (180 g) would meet 18-40% of the suggested polyphenol content, indicating that some of the Thai fruits are excellent sources of antioxidants. Liu et al., 200833 suggested that the content of phenolic compounds in fruit could be used as an indicator of its antioxidant capacity. Moreover, Scalbert et al., 200214 indicated that consumption of 1 g of polyphenol per day is able to promote gut health and general well-being. In addition, a number of studies have also indicated that polyphenols have protective affects against cardiovascular diseases, cancer, and other degenerative diseases9,34-36. Conclusion

The present study has shown that Thai fruits are not only excellent sources of macro-minerals, especially K, but also of antioxidant contents. Thus Thai fruits (in particular durian, guava, lychee, star fruit, strawberry, and sugar apple) can provide health benefits by supplying natural antioxidants that may help prevent NCDs. Acknowledgements

The authors thank Mahidol University for support grant and Professor Prapon Wilairat for assistance in editing the manuscript.

ªï∑’Ë 43 ©∫—∫∑’Ë 4 μÿ≈“§¡ - ∏—𫓧¡ 2551

R1_Nutrition_p17-27_pro1.indd Sec1:25

25

6/22/09 10:53:01 PM


References

1. World Health Organization. The world health report. Preventing chronic diseases: a vital investment. Geneva: World Health Organization, 2005. 2. Burt VL, Whelton P, Roccella EJ, Brown C, Cutler JA, Higgins M, et al. Prevalence of hypertension in the US adult population. Results from the third national health and nutrition examination survey, 1988-1991. Hypertension. 1995;25(3):305-13. 3. Ministry of Public Health. Bureau of Policy and Strategy. Thailand health profile. Public Health Statistics, Thailand 1997-2004. 4. Coresh J, Astor BC, Greene T, Eknoyan G, Levey AS. Prevalence of chronic kidney diseases and decreased kidney function in the adult US population: Third national Health and Nutrition Examination Survey. Am J Kidney Dis. 2003;41(1):1-12. 5. Chadban J, Briganti EM, Kerr PG, Dunstan DW, Welborn TA, Zimmet PZ, et al. Prevalence of kidney damage in Australian adults: The AusDiab Kidney Study. J Am Soc Nephrol. 2003;14 Supple:S131-8. 6. Ramirez SP, McClellan W, Port FK, Hsu SI. Risk factors for proteinuria in a large multitracial, Southeast Asian population. J Am Soc Nephrol. 2002;13 (7):907-17. 7. Chittinandana A. Thailand renal replacement therapy registry, TRT registry report. 1997-2000. J Nephrol Soc Thailand. 2002;8():167-79. 8. Hung H, Joshipura K, Jiang R, Hu F, Hunter D, Smith-Warner S, et al. Fruit and vegetable intake and risk of major chronic disease. J Natl Cancer Inst. 2004;96(21):1577-84. 9. Dauchet L, Amouyel P, Hercberg S, Dallongeville J. Fruit and vegetable consumption and risk of coronary heart diseases: A meta-analysis of cohort studies. J Nutr. 2006;136(10):2588-93. 10. Austin GL, Adair LS, Galanko JA, Martin CF, Satia JA, Sandler RS. A diet high in fruit and low in meats reduces the risk of colorectal adonomas. J Nutr. 2007;137(4),999-1004. 11. Lim YY, Lim TT, Tee JJ. Antioxidant properties of several tropical fruits: A comparative study. Food Chem. 2007;103(3):1003-8. 12. Leong LP, Shui G. An investigation of antioxidant capacity of fruits in Singapore markets. Food Chem. 2002;76(1):69-75. 13. Schaefer S, Baum M, Eisenbrand G, Dietrich H, Will F, Janzowski C. Polyphenolic apple juice extracts and their major constituents reduce oxidative damage in human colon cell lines. Mol Nutr Food Res. 2006;50(1),24-33. 14. Scalbert A, Morand C, Manach C, Remesy C Absorption and metabolism of polyphenolic in the gut and impact on health. Biomed Pharmacother. 2002;56(6):276-82. 15. Puwastien P, Raroengwichit M, Sungpuag P, Judprasong K. Thai Food Composition Tables. 1st ed. Institute of Nutrition, Mahidol University (INMU), Thailand. ASEANFOODS Regional Database Centre of INFOODS, 1999. 16. Official Method of Analysis of Official Analytical Chemists (AOAC). In: Horwitz W, editor. 17th ed. Association of official Analytical Chemists, Gaithersburg, MD, 2005. 17. Brune M, Hallberg L, Skanberg A. Determination of iron-binding phenolic groups in foods. J Food Sci. 1991;56(1) :128-31. 18. Somsub W, Kongkachuichai R, Sungpuag P, Charoensiri R. Effects of three conventional cooking methods on vitamin C, tannin, myo-inositol phosphates contents in selected Thai vegetables. J Food Compost Anal. 2008;21(2):187-97. 19. Hotz C, Gibson RS. Assessment of home-base processing methods to reduce the phytate content and phytate/zinc molar ratio of maize (Zima’s). J Agric Food Chem. 2001;49(2):692-8. 26

«“√ “√‚¿™π“°“√

R1_Nutrition_p17-27_pro1.indd Sec1:26

6/22/09 10:53:01 PM


20. Ministry of Public Health, Nutrition Division, Department of Health. Dietary reference intake for Thais. Nonthaburi: The Express Transportation Organization of Thailand Publishing, Bangkok, 2003. 21. Kongkachuichai R. Macro-element contents in Thai vegetables and fruits J Nutr Assoc Thailand. 1990;24(1):9-16. 22. Leterme P, Buldgen A, Estrada F, Londono AM. Mineral content of tropical fruits and unconventional foods of the Andes and the rain forest of Colombia. Food Chem. 2006;95(4):644-52. 23. Wall MM. Ascorbic acid, vitamin A and mineral composition of banana (Musa sp.) and papaya (Carica papaya) cultivars grown in Hawaii. J Food Compost Anal. 2006;19(5):434-45. 24. Hardisson A, Rubio C, Baez A, Martin M, Alvarez R, Diaz E. Mineral composition of the banana (Musa acuminata) from the island of Tenerife. Food Chem. 2001;73(2):153-61. 25. Sanchez-Castillo CP, Dewey PJS, Aguire A, Lara JJ, Vaca R, Barra PL, et al. The mineral content of Mexican fruits and vegetables. J Food Compost Anal. 1998;11(4):340-56. 26. Wall MM. Ascorbic acid and mineral composition of longan (Dimocarpus longan), lychee (Lichit chinensis) and rambutan (Nephelium lappaceum) cultivars grown in Haweii. J Food Compost Anal. 2006;19(6-7):655-63. 27. Hakala M, Lapvetelainen A, Huopalahti R, Kallio H, Tahvonen R. Effects of varieties and cultivation conditions on the composition of strawberries. J Food Compost Anal. 2003;16(1):67-80. 28. Ekholm P, Reinivuo H, Mattila P, Pakkala H, Koponen J, Happonen A, et al. Changes in the mineral and trance element contents of cereals, fruits and vegetables in Finland. J Food Compost Anal. 2007;20(6):487-95. 29. Forster MP, Rodriguez ER, Martin JD, Romero CD. Statistical differentiation of banana according to their mineral composition. J Agric and Food Chem. 2002;50(21):6130-5. 30. Cieslik E, Greda A, Adamus W. Contents of polyphenols in fruits and vegetables. Food Chem. 2006;94(1):135-42. 31. Rababah TM, Ereifej K, Howard L. Effect of ascorbic acid and dehydration on concentrations of total phenolics, antioxidant capacity, anthocyanins, and color in fruits. J Agric Food Chem. 2005;53(11):4444-7. 32. Scalbert A, Williamson G. Dietary intake and bioavailability of polyphenols. J Nutr. 2000;130 Supple:2073S-2085S. 33. Liu H, Qiy N, Ding H, Yao R. Polyphenol contents and antioxidant capacity of 68 Chinese herbals suitable for medical or food uses. Food Res Intern. 2008;41(4):363-70. 34. Leontowicz H, Leontowicz M, Drzewiecki J, Jastrzebski Z, Haruenki R, Poovarodom S, et al. Two exotic fruits positively effect rat’s plasma composition. Food Chem. 2007;102(1):192-200. 35. Gorinstein S, Caspi A, Libman I, Lerner HT, Huang D, Leontowicz H, et al. Red grape fruit positive influence serum triglyceride level in patients suffering from coronary atherosclerosis; study in vitro and in humans. J Agric Food Chem. 2006;54 (5):1887-92. 36. Halvorsen BL, Carlsen MH, Phillips KM, Bohn SK, Holte K, Jacobs Jr. DR, et al. Content of redoxactive compounds i.e., antioxidants in foods consumed in the United States. Am J Clin Nutr. 2006;84(1):95-135. 37. Wheeler ML, Daly A, Evert A, Franz MJ, Geil P, Holzmeister LA, et al. Choose your foods: Exchange lists for diabetes, 6th ed. Description and guidelines for use. J Am Diet Assoc. 2008;108(5):88.

ªï∑’Ë 43 ©∫—∫∑’Ë 4 μÿ≈“§¡ - ∏—𫓧¡ 2551

R1_Nutrition_p17-27_pro1.indd Sec1:27

27

6/22/09 10:53:01 PM


Nutrition àÇ³Ô¡Ò àºçÞ¨¾§É1,6 ÇÕÃÂÒ ¡ÒþҹԪ2 »Â¹Øª ÇÔàÈɪÒμÔ3 ¡Íºá¡ŒÇ ¢Ñ¹μÕ2 ¨ÒÃØ³Õ Ç§ÈàÅç¡2

Research Wenika Benjapong4,6 Weeraya Karnpanit4, Piyanuch Visetchart5, Kobkaew Kuntee4, Jarunee Wonglek4

°“√ª√–‡¡‘𧫓¡‡ ’ˬ߰“√‰¥â√—∫ —¡º—  ’ —߇§√“–À庠¡Õ“À“√

®“°°“√∫√‘‚¿§Õ“À“√¢Õ߇¥Á°π—°‡√’¬π „π‡¢μ‡¡◊ÕߢÕß°√ÿ߇∑æ¡À“π§√ ·≈–‡¢μ™π∫∑¢Õß®—ßÀ«—¥π§√ª∞¡ Risk assessment of synthetic food colors from dietary intake of school children in urban Bangkok and rural Nakhon Pathom

1 2 3 4 5 6

28

¼ÙŒª‹ÇÂÈÒÊμÃÒ¨ÒÏ ´Ã. ½†Ò¾ÔÉÇÔ·ÂÒ·Ò§ÍÒËÒÃáÅÐâÀª¹Ò¡Òà ʶҺѹÇÔ¨ÑÂâÀª¹Ò¡Òà Á.ÁËÔ´Å ÈÒÅÒÂÒ ¾Ø·¸Á³±Å ¨.¹¤Ã»°Á 73170 ½†Ò¾ÔÉÇÔ·ÂÒ·Ò§ÍÒËÒÃáÅÐâÀª¹Ò¡Òà ʶҺѹÇÔ¨ÑÂâÀª¹Ò¡Òà Á.ÁËÔ´Å ÈÒÅÒÂÒ ¾Ø·¸Á³±Å ¨.¹¤Ã»°Á 73170 ʶÔμÔáÅкÃÔ¡ÒäÍÁ¾ÔÇàμÍÏ ʶҺѹÇÔ¨ÑÂâÀª¹Ò¡Òà Á.ÁËÔ´Å ÈÒÅÒÂÒ ¾Ø·¸Á³±Å ¨.¹¤Ã»°Á 73170 Food and nutrition toxicology division, Institute of Nutrition, Mahidol University, Salaya, Phutthamonthon, Nakhon-Pathom 73170, Thailand Statistic and computer service, Institute of Nutrition, Mahidol University Correspondence, e-mail: nuwbe@mahidol.ac.th Tel. 0-2800-2380 μ‹Í 311, Fax 0-2441-9344

«“√ “√‚¿™π“°“√

R1_Nutrition_p28-37_pro1.indd Sec1:28

6/22/09 11:04:51 PM


∫∑§—¥¬àÕ

¡ÒÃä´ŒÃѺÊÕÊѧà¤ÃÒÐˏ¼ÊÁÍÒËÒÃã¹»ÃÔÁÒ³Ê٧໚¹Ë¹Öè§ã¹»˜ÞËÒÊÓ¤ÑÞ·ÕèÊ‹§¼ÅàÊÕÂμ‹ÍÊØ¢ÀÒ¾¼ÙŒºÃÔâÀ¤ â´Â੾ÒÐà´ç¡ «Öè§à»š¹¡ÅØ‹Á·Õè¹ÔÂÁºÃÔâÀ¤ÍÒËÒüÊÁÊÕ ¡ÒÃÈÖ¡ÉÒ¹Õé¨Ö§ÁÕÇÑμ¶Ø»ÃÐʧ¤à¾×èÍ»ÃÐàÁÔ¹¡ÒÃä´Œ ÃѺÊÑÁ¼ÑÊÊÕÊѧà¤ÃÒÐˏ¼ÊÁÍÒËÒÃã¹à´ç¡¹Ñ¡àÃÕ¹ áÅйÓä»»ÃÐàÁÔ¹¤ÇÒÁàÊÕ觢ͧ¡ÒÃä´ŒÃѺÊÑÁ¼ÑÊà»ÃÕº à·Õº¡Ñº¤‹Ò ADI (Acceptable Daily Intake) «Öè§à»š¹¤‹Ò·ÕèºÍ¡¶Ö§ÃдѺ·Õè»ÅÍ´ÀÑÂμ‹Í¡ÒÃä´ŒÃѺÊÑÁ¼ÑÊ â´Â¡ÒûÃÐàÁÔ¹¡ÒÃä´ŒÃѺÊÑÁ¼ÑÊÊÕÊѧà¤ÃÒÐˏ¼ÊÁÍÒËÒÃã¹à´ç¡¹Ñ¡àÃÕ¹ÍÒÂØ 6-18 »‚ ·ÕèÍÒÈÑÂã¹à¢μàÁ×ͧ ¢Í§¡Ãا෾ÁËÒ¹¤Ã áÅÐà¢μª¹º·¢Í§¨Ñ§ËÇÑ´¹¤Ã»°Á â´Â¹Ó¢ŒÍÁÙÅ¡ÒúÃÔâÀ¤ÍÒËÒüÊÁÊÕ áÅÐ »ÃÔÁÒ³ÊÕ·Õ辺ã¹ÍÒËÒÃÁҤӹdz»ÃÔÁÒ³¡ÒÃä´ŒÃѺÊÑÁ¼ÑÊÊÕμÒÁËÅÑ¡¡Òâͧ¤ÇÒÁ¹‹Ò¨Ð໚¹·Ò§Ê¶ÔμÔ ¼Å¡ÒÃÊÓÃǨ¾º¡ÒÃ㪌ÊÕÊѧà¤ÃÒÐˏ 7 ª¹Ô´ã¹¼ÅÔμÀѳ±ÍÒËÒ÷Ñé§ËÁ´ 75 ÃÒ¡Òà ¨Ò¡ 13 ¡ÅØ‹Á ÍÒËÒ÷Õèà´ç¡¹ÔÂÁºÃÔâÀ¤ â´ÂÊÕ·Ñé§ËÁ´à»š¹ÊÕÊѧà¤ÃÒÐˏ¼ÊÁÍÒËÒê¹Ô´·ÕèÊӹѡ§Ò¹¤³Ð¡ÃÃÁ¡ÒÃÍÒËÒà áÅÐÂҢͧ»ÃÐà·Èä·Â͹ØÞÒμãˌ㪌ã¹ÍÒËÒÃä´Œ áμ‹¡ÅѺ¾º¡ÒÃ㪌ÊÕã¹»ÃÔÁÒ³·ÕèÊÙ§à¡Ô¹¤‹Ò·Õè¡®ËÁÒ ¡Ó˹´ã¹μÑÇÍ‹ҧÍÒËÒÃÃŒÍÂÅÐ 9 áÅÐÁÕ¡ÒÃ㪌ÊÕÊѧà¤ÃÒÐˏ¼ÊÁÍÒËÒÃã¹ÍÒËÒ÷ÕèäÁ‹Í¹ØÞÒμãËŒãÊ‹ÊÕ ËÅÒÂÃÒ¡Òà ¨Ò¡¡ÒûÃÐàÁÔ¹¡ÒÃä´ŒÃѺÊÑÁ¼ÑÊ·ÕèÃдѺà©ÅÕè¢ͧ¡ÒúÃÔâÀ¤ ¾ºÇ‹Ò¡ÒÃä´ŒÃѺÊÑÁ¼ÑÊ ÊÕÊѧà¤ÃÒÐˏ¼ÊÁÍÒËÒÃËÅÒª¹Ô´¢Í§à´ç¡¹Ñ¡àÃÕ¹㹾×é¹·Õ誹º·¢Í§¨Ñ§ËÇÑ´¹¤Ã»°ÁÁÕ¤‹ÒÊÙ§¡Ç‹Òà´ç¡ ¹Ñ¡àÃÕ¹㹾×é¹·ÕèàÁ×ͧ¢Í§¡Ãا෾ÁËÒ¹¤Ã àÁ×èÍ»ÃÐàÁÔ¹¤ÇÒÁàÊÕ觢ͧ¡ÒÃä´ŒÃѺÊÑÁ¼ÑÊà»ÃÕºà·Õº¡Ñº¤‹Ò ADI ¢Í§ÊÕª¹Ô´¹Ñé¹ ¾ºÇ‹Ò¡ÒÃä´ŒÃѺÊÕÊѧà¤ÃÒÐˏ¼ÊÁÍÒËÒ÷ءª¹Ô´ã¹»ÃЪҡáÅØ‹Á¹ÕéÁÕ¤‹ÒμèÓ¡Ç‹Ò¤‹Ò ADI â´ÂÊÕÊѧà¤ÃÒÐˏ·ÕèÁÕ¤‹Òà©ÅÕè¢ͧ»ÃÔÁÒ³¡ÒÃä´ŒÃѺÊÑÁ¼ÑÊàÁ×èÍà»ÃÕºà·Õº¡Ñº¤‹Ò ADI ÊÙ§¡Ç‹ÒÊÕÍ×è¹ã¹¡ÅØ‹Á ¢Í§à´ç¡¹Ñ¡àÃÕ¹ÃдѺ»ÃжÁáÅÐÁѸÂÁÈÖ¡ÉҢͧ¡Ãا෾ÁËÒ¹¤Ã ¤×Í ¤ÒÏâÁÍÕ«Õ¹ «Öè§ÁÕ¤‹Òà¾Õ§ÌÍÂÅÐ 5 áÅÐ 3 ¢Í§¤‹Ò ADI μÒÁÅӴѺ ¢³Ð·Õè㹡ÅØ‹Á¢Í§à´ç¡¹Ñ¡àÃÕ¹ÃдѺ»ÃжÁáÅÐÁѸÂÁÈÖ¡ÉҢͧ ¨Ñ§ËÇÑ´¹¤Ã»°Á ¤×Í àÍÍÃÔâ¸Ã«Õ¹ «Öè§ÁÕ¤‹Ò෋ҡѺÌÍÂÅÐ 25 áÅÐ 16 ¢Í§¤‹Ò ADI μÒÁÅӴѺ ¨Ö§ ¶×ÍÇ‹Ò¡ÒÃä´ŒÃѺÊÑÁ¼ÑÊÊÕÊѧà¤ÃÒÐˏ¼ÊÁÍÒËÒÃàËÅ‹Ò¹Õé·ÕèÃдѺ¡ÒúÃÔâÀ¤à©ÅÕèÂã¹»ÃЪҡáÅØ‹Á¹ÕéÂѧÍÂÙ‹ã¹ ÃдѺ·ÕèäÁ‹¹‹Ò¨Ð¡‹Í¼ÅàÊÕÂμ‹ÍÊØ¢ÀÒ¾ à¹×èͧ¨Ò¡»ÃÔÁÒ³¡ÒÃä´ŒÃѺÊÑÁ¼ÑÊÁÕ¤‹ÒμèÓ¡Ç‹Ò¤‹Ò ADI ÁÒ¡ á싶ŒÒ »ÃÐàÁÔ¹ã¹ÃдѺ¡ÒúÃÔâÀ¤·ÕèÊ٧ઋ¹·ÕèÃдѺ 97.5 à»ÍÏà«ç¹μä·Å ¾ºÇ‹Ò㹡ÅØ‹Áà´ç¡¹Ñ¡àÃÕ¹㹨ѧËÇÑ´ ¹¤Ã»°Á ËÒ¡ÁÕ¡ÒúÃÔâÀ¤äÊŒ¡ÃÍ¡áÅÐÅÙ¡ªÔé¹à¾Õ§ 2 ÃÒ¡ÒÃã¹»ÃÔÁÒ³ÁÒ¡ ¨ÐÁÕâÍ¡ÒÊä´ŒÃѺÊÑÁ¼ÑÊÊÕ àÍÍÃÔâ¸Ã«Õ¹ÊÙ§¶Ö§ÃŒÍÂÅÐ 108 ¢Í§ ADI ´Ñ§¹Ñ鹨֧¤ÇÃÁÕ¡ÒÃཇÒÃÐÇѧ¡ÒÃ㪌ÊÕÊѧà¤ÃÒÐˏã¹ÍÒËÒûÃÐàÀ· äÊŒ¡ÃÍ¡áÅÐÅÙ¡ªÔ鹫Öè§à»š¹·Õè¹ÔÂÁºÃÔâÀ¤ã¹¡ÅØ‹Áà´ç¡¹Ñ¡àÃÕ¹ ¤ÓÊÓ¤ÑÞ : ÊÕÊѧà¤ÃÒÐˏ¼ÊÁÍÒËÒà ¡ÒûÃÐàÁÔ¹¤ÇÒÁàÊÕè§ à´ç¡¹Ñ¡àÃÕ¹

ªï∑’Ë 43 ©∫—∫∑’Ë 4 μÿ≈“§¡ - ∏—𫓧¡ 2551

R1_Nutrition_p28-37_pro1.indd Sec1:29

29

6/22/09 11:04:51 PM


Abstract

High exposure to synthetic food colors is one important problem that may provide adverse health effects to consumers, especially in children who like to consume colored foods. This study aimed to estimate the daily dietary intake of synthetic food colors in school children and assess the risk of exposure by comparing the daily intake with the ADI (Acceptable Daily Intake - the safety margin of exposure). The intakes of synthetic food colors in school children, aged 6-18 years, living in urban areas of Bangkok and rural areas of Nakhon Pathom province were estimated by the probabilistic analysis of data on colored food consumption and the concentration of colors found in those foods. The survey found seven types of synthetic colors in 75 items of 13 food categories popular among children. All colors were synthetic food colors permitted for use in food products by Thai FDA. However, 9% of food samples contained the food colors over the permitted levels. Moreover, synthetic food colors were also found in many food items not permitted to contain the colors. Estimated intake from mean level consumption indicated that the exposures of most synthetic food colors by Nakhon Pathom school children were higher than those by Bangkok school children. Population risk was characterized by comparison of estimated intake with the ADI showed that the exposures of all synthetic food colors in these populations were less than the ADI. The exposure of carmoisine provided the highest percentage of the ADI in Bangkok primary and secondary school children, the mean intakes were only 5% and 3% of the ADI, respectively. Whereas, the mean intake of erythrosine provided the highest percentage of the ADI in Nakhon Pathom primary and secondary school children, were 25% and 16% of the ADI, respectively. In conclusion, the consumption of colored foods by Bangkok and Nakhon Pathom school children at mean level did not provide adverse health risk as a result that total exposures of each synthetic food color were very lower than the ADI. However, high level consumers of sausage and meatball may pose a risk of health effects. Consumption of sausage and meatball at 97.5th percentile provided high exposure of erythrosine in Nakhon Pathom school children by 108% of ADI. Thus the using of synthetic food colors is necessary to stringent control, especially in sausages and meatballs which are popular among the school children. Keywords : Synthetic food color, risk assessment, school children

30

«“√ “√‚¿™π“°“√

R1_Nutrition_p28-37_pro1.indd Sec1:30

6/22/09 11:04:51 PM


∫∑π”

ÊÕÊѧà¤ÃÒÐˏ¼ÊÁÍÒËÒÃ໚¹ÇÑμ¶Øà¨×Í»¹ÍÒËÒëÖ觹ÔÂÁ㪌㹠¡ÒüÅÔμÍÒËÒÃËÅÒ»ÃÐàÀ· à¹×èͧ¨Ò¡ËÒ«×éÍä´Œ§‹Ò ÃÒ¤Ò¶Ù¡ áÅÐÊÒÁÒö¡Ó˹´»ÃÔÁÒ³¡ÒÃ㪌䴌ṋ¹Í¹ »˜¨¨ØºÑ¹¨Ö§¾º ÊÕÊѧà¤ÃÒÐˏà¨×Í»¹ã¹ÍÒËÒÃáÅÐà¤Ã×èͧ´×èÁÁÒ¡ÁÒÂËÅÒª¹Ô´·Õè ¨Ó˹‹ Ò Âã¹·Œ Í §μÅÒ´áÅÐ໚ ¹ ·Õè ¹Ô Â ÁºÃÔ â À¤¢Í§à´ç ¡ 1-3 ÊÕÊѧà¤ÃÒÐˏ·Õè͹ØÞÒμãˌ㪌ã¹ÍÒËÒùÑé¹ The Joint FAO/WHO Expert Committee on Food Additives (JECFA) ä´Œ ÃǺÃÇÁ¢ŒÍÁÙÅ¡ÒÃÈÖ¡ÉÒ·Ò§¾ÔÉÇÔ·ÂÒ·Ñé§ã¹ÊÑμǏ·´ÅͧáÅТŒÍÁÙÅ ·Ò§ÃкҴÇÔ·ÂÒã¹Á¹Øɏ ¹ÓÁÒ»ÃÐàÁÔ¹¤ÇÒÁ໚¹¾ÔÉ áÅÐ ¡Ó˹´¤‹Ò¤ÇÒÁ»ÅÍ´ÀÑ¢ͧ¡ÒÃä´ŒÃѺÊÕàËÅ‹Ò¹Ñé¹ã¹Á¹Øɏänj໚¹ ¤‹Ò Acceptable Daily Intake (ADI) «Öè§à»š¹»ÃÔÁÒ³·Õè Ëҧ¡ÒÂÊÒÁÒöÃѺ䴌μ‹ÍÇѹμÅÍ´ªÑèǪÕÇÔμâ´Â·ÕèäÁ‹·ÓãËŒà¡Ô´¼Å ¡Ãзºμ‹ÍÊØ¢ÀÒ¾ ´Ñ§¹Ñé¹ã¹¡ÒùÓÊÕáμ‹ÅЪ¹Ô´ä»ãÊ‹ã¹ÍÒËÒè֧ ¤Çäӹ֧¶Ö§¤‹Ò¤ÇÒÁ»ÅÍ´ÀÑ ËÃ×ͤ‹Ò ADI ¢Í§ÊÕª¹Ô´¹Ñé¹ æ4 à´ç¡à»š¹ÇÑ·ÕèËҧ¡ÒÂÁÕ¡ÒÃà¨ÃÔÞàμÔºâμ μŒÍ§ä´ŒÃѺÍÒËÒ÷ÕèÁÕ ¤Ø³¤‹ÒáÅÐà¾Õ§¾Í áμ‹»˜¨¨ØºÑ¹ÍÒËÒ÷Õèà´ç¡¹ÔÂÁºÃÔâÀ¤Áѡ໚¹ ÍÒËÒüÊÁÊÕ ÊÕÊѧà¤ÃÒÐˏ໚¹ÊÒ÷ÕèäÁ‹Áդس¤‹Ò·Ò§âÀª¹Ò¡Òà ÍҨʋ § ¼ÅàÊÕ Â μ‹ Í ÊØ ¢ ÀÒ¾¶Œ Ò ä´Œ ÃÑ º ã¹»ÃÔ Á Ò³ÁÒ¡à¡Ô ¹ ä» ÍѹμÃÒ¢ͧÊÕÊѧà¤ÃÒÐˏ¼ÊÁÍÒËÒÃÁÒ¨Ò¡ÍѹμÃÒ¨ҡμÑÇÊÕàͧ áÅÐÍѹμÃÒ¨ҡÊÒû¹à»„œÍ¹·Õèà¡Ô´¢Öé¹ÃÐËÇ‹Ò§¡Ãкǹ¡ÒüÅÔμ ઋ¹ âÅËÐ˹ѡ ໚¹μŒ¹5,6 ¡ÒÃཇÒÃÐÇѧäÁ‹ãËŒ¼ÙŒºÃÔâÀ¤ä´ŒÃѺ ÊÕ ÊÑ § à¤ÃÒÐˏ ¼ ÊÁÍÒËÒèҡ¡ÒúÃÔ â À¤ÍÒËÒÃáÅÐà¤Ã×è Í §´×è Á à¡Ô¹¤‹Ò ADI ¨Ö§ÁÕ¤ÇÒÁ¨Ó໚¹Í‹ҧÂÔè§ ã¹ ¾.È. 2547 Êӹѡ§Ò¹¤³Ð¡ÃÃÁ¡ÒÃÍÒËÒÃáÅÐÂÒ ¡ÃзÃǧÊÒ¸ÒóÊØ¢ ¡àÅÔ¡»ÃСÒÈ¡ÃзÃǧÊÒ¸ÒóÊØ¢ ©ºÑº·Õè 66 (¾.È. 2525) àÃ×èͧ¡Ó˹´ÊÕ¼ÊÁÍÒËÒÃ໚¹ÍÒËÒà ¤Çº¤ØÁ੾ÒÐ7 â´Âãˌ㪌»ÃСÒÈ¡ÃзÃǧÊÒ¸ÒóÊØ¢©ºÑº·Õè 281 (¾.È. 2547) àÃ×èͧ ÇÑμ¶Øà¨×Í»¹ÍÒËÒà ᷹8 »ÃСÒÈ ¡ÃзÃǧÊÒ¸ÒóÊØ¢©ºÑº¹Õéä´Œ¡Ó˹´»ÃÔÁÒ³ÊÙ§ÊØ´¢Í§¡ÒÃ㪌 ÊÕÊѧà¤ÃÒÐˏ·Õè͹ØÞÒμãˌ㪌ã¹ÍÒËÒÃáμ¡μ‹Ò§¡Ñ¹ä»μÒÁª¹Ô´¢Í§ ÊÕáÅЪ¹Ô´¢Í§ÍÒËÒà áÅÐμÒÁÁÒμðҹ¢Í§ Codex9 Í‹ҧäà ¡çμÒÁâÍ¡ÒÊ㹡ÒÃä´ŒÃѺÊÑÁ¼ÑÊÊÕÊѧà¤ÃÒÐˏ¼ÊÁÍÒËÒèҡ¡Òà ºÃÔâÀ¤ÍÒËÒâͧ»ÃЪҡÃáμ‹ÅлÃÐà·ÈÁÕ¤ÇÒÁáμ¡μ‹Ò§¡Ñ¹ μÒÁ¾ÄμÔ¡ÃÃÁ¡ÒúÃÔâÀ¤ ´Ñ§¹Ñ鹡ÒûÃѺᡌÁÒμðҹÍÒËÒè֧ ¤ÇùÓËÅÑ¡¡ÒûÃÐàÁÔ¹¤ÇÒÁàÊÕè§ «Öè§à»š¹·ÕèÂÍÁÃѺ㹻˜¨¨ØºÑ¹Ç‹Ò ÁÕ¤ÇÒÁ¨Ó໚¹μŒÍ§¹ÓÁÒ»ÃСͺ¡ÒþԨÒóÒ㹡ÒáÓ˹´¤‹Ò ÁÒμðҹÊÓËÃѺ㪌ã¹ÍÒËÒà »˜¨¨ØºÑ¹»ÃÐà·Èä·ÂÂѧ¢Ò´¢ŒÍÁÙÅ¡ÒÃä´ŒÃѺÊÑÁ¼ÑÊÊÕÊѧà¤ÃÒÐˏ ¼ÊÁÍÒËÒÃã¹»ÃЪҡáÅØ‹Áμ‹Ò§ æ ¨Ö§à¡Ô´»˜ÞËÒ㹡ÒáÓ˹´

¤‹ÒÁÒμðҹ·ÕèàËÁÒÐÊÁ ´Ñ§¹Ñé¹à¾×èÍ໚¹¡Òä،Á¤Ãͧ¼ÙŒºÃÔâÀ¤ã¹ »ÃÐà·È ¨Ö§¤ÇÃÁÕ¡ÒûÃÐàÁÔ¹¤ÇÒÁàÊÕ觢ͧ¡ÒÃä´ŒÃѺÊÑÁ¼ÑÊ ÊÕÊѧà¤ÃÒÐˏ¼ÊÁÍÒËÒèҡ¡ÒúÃÔâÀ¤ÍÒËÒâͧ¤¹ä·Â â´Â ੾ÒÐà´ç¡«Öè§à»š¹¡ÅØ‹Á·ÕèÁÕ¤ÇÒÁàÊÕè§Ê٧㹡ÒÃä´ŒÃѺÊÕÊѧà¤ÃÒÐˏ ¼ÊÁÍÒËÒà à¹×èͧ¨Ò¡à»š¹¡ÅØ‹Á·Õè¹ÔÂÁºÃÔâÀ¤ÍÒËÒÃá싧ÊÕáÅÐÁÕ ¹éÓ˹ѡμÑǹŒÍ ¡ÒÃÇԨѹÕé¨Ö§ÁØ‹§à»‡ÒËÁÒÂä»·Õè¡ÒûÃÐàÁÔ¹¤ÇÒÁàÊÕ觢ͧ¡Òà 䴌 ÃÑ º ÊÑ Á ¼Ñ Ê ÊÕ ÊÑ § à¤ÃÒÐˏ ¼ ÊÁÍÒËÒÃ㹡ÅØ‹ Á àÊÕè  § ¤× Í à´ç ¡ ¹Ñ¡àÃÕ¹·ÕèÍÒÈÑÂã¹àÁ×ͧáÅÐ㹪¹º·¢Í§ÀÒ¤¡ÅÒ§ â´Â¢ŒÍÁÙÅ·Õè ä´Œ ¨ Ò¡§Ò¹ÇÔ ¨Ñ  ¹Õé ¨ ÐÁÕ » ÃÐ⪹ ã ¹¡ÒùÓä»»ÃСͺ¡Òà ¾Ô¨ÒóһÃѺ»ÃاËÃ×Í¡Ó˹´»ÃÔÁÒ³ÊÙ§ÊØ´·Õè¤ÇÃ͹ØÞÒμãËŒ 㪌ÊÕÊѧà¤ÃÒÐˏ¼ÊÁÍÒËÒÃã¹ÍÒËÒûÃÐàÀ·μ‹Ò§ æ áÅÐ໚¹ á¹Ç·Ò§¨Ñ ´ ¡ÒÃãËŒ à ¡Ô ´ ¤ÇÒÁ»ÅÍ´ÀÑ Â㹡ÒúÃÔ â À¤ÍÒËÒà ÃÇÁ·Ñé§Ê¹ÑºÊ¹Ø¹ãËŒà¡Ô´¾ÄμÔ¡ÃÃÁ¡ÒúÃÔâÀ¤ÍÒËÒ÷Õè»ÅÍ´ÀÑ μ‹ÍÊØ¢ÀÒ¾¢Í§à´ç¡μ‹Íä» «—μ∂ÿª√– ß§å

»ÃÐàÁÔ ¹ ¡ÒÃä´Œ ÃÑ º ÊÑ Á ¼Ñ Ê (exposure assessment) ÊÕ ÊÑ § à¤ÃÒÐˏ ¼ ÊÁÍÒËÒâͧà´ç ¡ ¹Ñ ¡ àÃÕ Â ¹ã¹¾×é ¹ ·Õè à Á× Í § ¤× Í ¡Ãا෾ÁËÒ¹¤Ã áÅо×é¹·Õ誹º· ¤×Í ¾×é¹·Õè¹Í¡à¢μà·ÈºÒÅ ¢Í§¨Ñ§ËÇÑ´¹¤Ã»°Á »ÃÐàÁÔ¹¤ÇÒÁàÊÕè§ (risk assessment) ¢Í§¡ÒÃä´ŒÃѺÊÑÁ¼ÑÊ ÊÕÊѧà¤ÃÒÐˏ¼ÊÁÍÒËÒèҡ¡ÒúÃÔâÀ¤ÍÒËÒÃã¹áμ‹ÅÐÇѹ¢Í§ à´ç¡¹Ñ¡àÃÕ¹㹾×é¹·ÕèàÁ×ͧ¢Í§¡Ãا෾ÁËÒ¹¤ÃáÅо×é¹·Õ誹º· ¢Í§¹¤Ã»°Á «‘∏’°“√«‘®—¬ ¡ÅØ‹ÁμÑÇÍ‹ҧ

μÑÇÍ‹ҧ»ÃЪҡáÅØ‹Á໇ÒËÁÒÂ໚¹à´ç¡¹Ñ¡àÃÕ¹·Ñé§à¾ÈªÒ áÅÐËÞÔ§ ÍÒÂØ 7-18 »‚ ẋ§à»š¹à´ç¡¹Ñ¡àÃÕ¹ÃдѺ»ÃжÁ ÈÖ ¡ ÉÒ ÍÒÂØ 7-12 »‚ áÅÐà´ç ¡ ¹Ñ ¡ àÃÕ Â ¹ÃÐ´Ñ º ÁÑ ¸ ÂÁÈÖ ¡ ÉÒ ÍÒÂØ 13-18 »‚ ¨Ò¡âçàÃÕ¹ã¹à¢μàÁ×ͧ (¡Ãا෾ÁËÒ¹¤Ã) ÃдѺÅÐ 2 âçàÃÕ¹ ÃÇÁ 4 âçàÃÕ¹ 䴌ᡋ âçàÃÕ¹ ÇÑ´âÊÁ¹ÑÊ âçàÃÕ¹ÇÑ´Á¡Ø®¡ÉÑμÃԏ âçàÃÕ¹ÃÒªÇÔ¹Ôμá¼¹¡ »ÃжÁ áÅÐâçàÃÕ¹ÃÒªÇÔ¹Ôμá¼¹¡ÁѸÂÁ áÅШҡâçàÃÕ¹㹠à¢μª¹º· (¹Í¡à¢μà·ÈºÒŹ¤Ã»°Á) ÃдѺÅÐ 2 âçàÃÕ¹ ÃÇÁ 4 âçàÃÕ¹ 䴌ᡋ âçàÃÕ¹ºŒÒ¹ËÅǧ âçàÃÕ¹ºŒÒ¹ËÅǧ ÇÔ·ÂÒ âçàÃÕ¹´Í¹ËÇÒ áÅÐâçàÃÕ¹ÀÑ·ÃÞÒ³ ¨Ó¹Ç¹ ·Ñé§ËÁ´ 400 ¤¹ ẋ§à»š¹¡ÅØ‹ÁÅÐ 100 ¤¹ ·Ó¡ÒÃÊØ‹ÁàÅ×Í¡ μÑÇÍ‹ҧÍ‹ҧÍÔÊÃШҡ»ÃЪҡÃà¾ÈËÞÔ§áÅÐà¾ÈªÒ¨ӹǹ ªï∑’Ë 43 ©∫—∫∑’Ë 4 μÿ≈“§¡ - ∏—𫓧¡ 2551

R1_Nutrition_p28-37_pro1.indd Sec1:31

31

6/22/09 11:04:51 PM


෋ҡѹ (μÒÃÒ§·Õè 1) â´Â¢¹Ò´¢Í§¡ÅØ‹ÁμÑÇÍ‹ҧ¤Ó¹Ç³¨Ò¡ÊÙμà ´Ñ§¹Õé N = 1.962 x P (1-P) 0.12 â´Â 1.96 = Z value for p = 0.05 or 95% confidence limit P = Estimated prevalence of synthetic food color consumption = 0.5 d = Desired precision, 0.1 for + 10% μÒÃÒ§·Õè 1

¡ÅØ‹Á»ÃЪҡÃμÑÇÍ‹ҧ ¡ÅØ‹ÁμÑÇÍ‹ҧ

âçàÃÕ¹ à¢μàÁ×ͧ (¡Ãا෾ÁËÒ¹¤Ã) à¢μª¹º· (¹Í¡à¢μà·ÈºÒŹ¤Ã»°Á)

¹Ñ¡àÃÕ¹ÃдѺ»ÃжÁÈÖ¡ÉÒ (ÍÒÂØ 7-12 »‚) ¹Ñ¡àÃÕ¹ÃдѺÁѸÂÁÈÖ¡ÉÒ (ÍÒÂØ 13 - 18 »‚) °“√‡°Á∫¢âÕ¡Ÿ≈¿“§ π“¡

ÊÓÃǨ¢Œ Í ÁÙ Å ¡ÒúÃÔ â À¤ÍÒËÒ÷Õè ÁÕ ¡ ÒûÃØ § áμ‹ § ÊÕ ã ¹ à´ç ¡ ¹Ñ ¡ àÃÕ Â ¹ÃÐ´Ñ º »ÃжÁáÅÐÃÐ´Ñ º ÁÑ ¸ ÂÁÈÖ ¡ ÉÒà¾×è Í ·ÃÒº »ÃÔÁÒ³áÅФÇÒÁ¶Õè㹡ÒúÃÔâÀ¤ áÅÐáËÅ‹§¨Ó˹‹ÒÂÍÒËÒà ÃÒ¡ÒùÑé¹ â´Â㪌ẺÊͺ¶ÒÁ¤ÇÒÁ¶Õè¢Í§¡ÒúÃÔâÀ¤ÍÒËÒà (food frequency questionnaires) áÅÐẺ¨ÓÅͧÍÒËÒà 㹡ÒÃà¡çº¢ŒÍÁÙÅ¡ÒúÃÔâÀ¤ à¡ç º μÑ Ç Í‹ Ò §ÍÒËÒüÊÁÊÕ ¨ Ò¡¾×é ¹ ·Õè ÈÖ ¡ ÉÒ â´Âà¡ç º μÑÇÍ‹ҧÍÒËÒÃÃÒ¡Ò÷Õèà´ç¡¹ÔÂÁºÃÔâÀ¤«Öè§ËÅѡࡳ±·Õè㪌 ¾Ô¨ÒóҨҡÃÒ¡Ò÷ÕèÁÕ»ÃÔÁÒ³¡ÒúÃÔâÀ¤μ‹ÍÇѹÊÙ§áÅÐ/ËÃ×Í ÃÒ¡Ò÷Õè ÁÕ ¤ ÇÒÁ¶Õè ¢ ͧ¡ÒúÃÔ â À¤ÊÙ § â´Â㹡ÒÃÈÖ ¡ ÉÒ¹Õé ¤Ñ´àÅ×Í¡ÃÒ¡ÒÃÍÒËÒÃÁÕ»ÃÔÁÒ³¡ÒúÃÔâÀ¤ÁÒ¡¡Ç‹Ò ÃŒÍÂÅÐ 1 ¢Í§»ÃÔÁÒ³¡ÒúÃÔâÀ¤ÍÒËÒüÊÁÊÕ·Ñé§ËÁ´áÅÐ/ËÃ×ÍÁÕ¤ÇÒÁ¶Õè 㹡ÒúÃÔâÀ¤ÁÒ¡¡Ç‹Ò 1 ¤ÃÑé§μ‹Í 10 Çѹ (¶ŒÒÍÒËÒÃÃÒ¡Òà ¹Ñé¹ÁÕ»ÃÔÁÒ³¡ÒúÃÔâÀ¤μèÓ¡Ç‹ÒÃŒÍÂÅÐ 1 áÅÐÂѧÁÕ¤ÇÒÁ¶Õè¢Í§ ¡ÒúÃÔâÀ¤μèÓ¡Ç‹Ò 1 ¤ÃÑé§ μ‹Í 10 Çѹ ¶×ÍÇ‹ÒäÁ‹ÁÕ¹ÑÂÊÓ¤ÑÞã¹ ¡ÒùÓÁҤӹdzËÒ»ÃÔÁÒ³¡ÒúÃÔâÀ¤) ·Ó¡ÒÃà¡çºμÑÇÍ‹ҧ ÍÒËÒèҡ 2 áËÅ‹§¨Ó˹‹Ò·Õèà´ç¡¹ÔÂÁ«×éÍ ä´Œá¡‹ Ìҹ¤ŒÒ ÀÒÂã¹âçàÃÕ¹ Ìҹ¤ŒÒÃͺâçàÃÕ¹ áÅÐμÅÒ´ ËÃ×Íˌҧ ÊÃþÊÔ¹¤ŒÒ«Öè§ÍÂÙ‹ã¹¾×é¹·ÕèÈÖ¡ÉÒ ¹ÓÁÒÇÔà¤ÃÒÐˏà¾×èÍÃкت¹Ô´ áÅлÃÔÁÒ³¢Í§ÊÕÊѧà¤ÃÒÐˏ·Õèà¨×Í»¹ã¹ÍÒËÒà NjÒ໚¹¡ÅØ‹Á ÊÕ ÊÑ § à¤ÃÒÐˏ ·Õè Í ¹Ø Þ ÒμËÃ× ÍäÁ‹ Í ¹Ø Þ ÒμãËŒ ã ªŒ ã ¹ÍÒËÒà â´Â ¾Ô¨ÒóÒμÒÁ»ÃСÒÈ¡ÃзÃǧÊÒ¸ÒóÊØ¢©ºÑº·Õè 281 àÃ×èͧ ÇÑμ¶Øà¨×Í»¹ÍÒËÒÃ7 32

100 ¤¹ 100 ¤¹

100 ¤¹ 100 ¤¹

°“√«‘‡§√“–Àåª√‘¡“≥ ’ —߇§√“–À庠¡Õ“À“√ „πμ—«Õ¬à“ßÕ“À“√

¹ÓμÑÇÍ‹ҧÍÒËÒÃÁÒÇÔà¤ÃÒÐˏᡪ¹Ô´ÊÕÊѧà¤ÃÒÐˏáÅÐ ÊÕ¸ÃÃÁªÒμÔ â´Âà·¤¹Ô¤ Wool dying10 ËÒ¡ÊÕ·Õè¼ÊÁã¹ ÍÒËÒÃ໚¹ÊÕÊѧà¤ÃÒÐˏ ¨Ð¾ºÇ‹ÒÊÕ¨Ò¡ÊÒÃÅÐÅÒÂμÑÇÍ‹ҧ㹠ÊÀÒÇзÕè໚¹¡Ã´¨ÐÂŒÍÁμÔ´äËÁ¾ÃÁ ᡪ¹Ô´ÊÕÊѧà¤ÃÒÐˏ ´Œ Ç Âà·¤¹Ô ¤ â¤ÃÁÒâμ¡ÃÒ¿¿‚ á ºº¡ÃдÒÉ (paper chromatography)11 áÅÐÇÔà¤ÃÒÐˏËÒ»ÃÔÁÒ³ÊÕÊѧà¤ÃÒÐˏâ´Â ÇÑ ´ ¤‹ Ò ¡Òô٠´ ¡Å× ¹ áʧ´Œ Ç Âà¤Ã×è Í §Ê໤âμÃâ¿âμÁÔ à μÍÏ (Shimadzu, Bara UV-Biospec 1601, Japan) ·Õè ¤ÇÒÁÂÒǤÅ×è¹ 505 ¹Òâ¹àÁμà ÊÓËÃѺ»Í§â« 4 ÍÒÏ, 515 ¹Òâ¹àÁμà ÊÓËÃѺ¤ÒÏâÁÍÕ«Õ¹, 505 ¹Òâ¹àÁμà ÊÓËÃѺ àÍÍÃÔ â ¸Ã«Õ ¹ , 480 ¹Òâ¹àÁμà ÊÓËÃÑ º «Ñ ¹ à«ç μ àÂç ÅâÅǏ àÍç¿«ÕàÍç¿, 430 ¹Òâ¹àÁμà ÊÓËÃѺμÒÏμÃÒ«Õ¹, 620 ¹Òâ¹àÁμà ÊÓËÃѺ¿ÒÊμ ¡ÃÕ¹ àÍç¿«ÕàÍç¿, 630 ¹Òâ¹àÁμà ÊÓËÃѺ ºÃÔÅàÅÕ¹· ºÅÙ àÍç¿«ÕàÍç¿ áÅÐ 615 ¹Òâ¹àÁμà ÊÓËÃѺ ÍÔ¹´Ôâ¡μÔ¹ ¤Ó¹Ç³»ÃÔÁÒ³ÊÕÊѧà¤ÃÒÐˏâ´Âà»ÃÕºà·Õº¤‹Ò¡Ñº ÊÒÃÅÐÅÒÂÁÒμðҹ¢Í§ÊÕáμ‹ÅЪ¹Ô´ °“√ª√–‡¡‘𧫓¡‡ ’ˬߢÕß°“√‰¥â√—∫ —¡º—   ’ —߇§√“–À庠¡Õ“À“√

»ÃÐàÁÔ¹¡ÒÃä´ŒÃѺÊÑÁ¼ÑÊμÒÁ Guideline ¢Í§ JECFA12 â´Â¹Ó¢ŒÍÁÙÅ¡ÒúÃÔâÀ¤áÅлÃÔÁÒ³ÊÕã¹ÍÒËÒÃÁÒ»ÃÐàÁÔ¹¡Òà 䴌ÃѺÊÑÁ¼ÑÊâ´ÂÇÔ¸Õ Probabilistic estimation »ÃСͺ¡Ñº

«“√ “√‚¿™π“°“√

R1_Nutrition_p28-37_pro1.indd Sec1:32

6/22/09 11:04:51 PM


â»Ãá¡ÃÁ»ÃÐÁÇżÅ੾ÒÐ @ RISK «Öè§ÊÒÁÒö»ÃÐÁÇżŠ¨Ò¡¢ŒÍÁÙÅÃÒºؤ¤ÅËÃ×ÍÃÒÂμÑÇÍ‹ҧ à¾×èÍá»Å¼Å ³ ÃдѺ ¤ÇÒÁ¹‹Ò¨Ð໚¹μ‹Ò§ æ ¹ÓÁҤӹdz»ÃÔÁÒ³¡ÒÃä´ŒÃѺÊÑÁ¼ÑÊ ¨Ò¡ÊÁ¡Òà ´Ñ§¹Õé

à¤Ã×èͧ´×èÁ 䴌ᡋ ¹éÓËÇÒ¹·Ñé§ÍÑ´ÅÁáÅÐäÁ‹ÍÑ´ÅÁ ¹éÓËÇÒ¹ÃÊ ¼ÅäÁŒ ªÒàÂç¹ à»š¹μŒ¹ ÃͧŧÁÒ¤×Í ¡ÅØ‹Á¢¹ÁËÇÒ¹ 䴌ᡋ ¹éÓá¢ç§äÊ äÍÈ¡ÃÕÁËÇÒ¹àÂç¹ ºÑÇÅÍ ໚¹μŒ¹ μÒÁ´ŒÇ¡ÅØ‹Á ¹ÁáÅмÅÔμÀѳ±¨Ò¡¹Á 䴌ᡋ ¹Á»Ãاá싧 ¹Áà»ÃÕéÂÇ

Exposure (intake) = E (Food consumption X Concentration of color) BW Exposure Food consumption Concentration of color BW

¤×Í ¤×Í ¤×Í ¤×Í

»ÃÔÁÒ³¡ÒÃä´ŒÃѺÊÑÁ¼ÑÊÊÕÊѧà¤ÃÒÐˏ¨Ò¡¡ÒúÃÔâÀ¤ÍÒËÒà (ÁÔÅÅÔ¡ÃÑÁ/¡ÔâÅ¡ÃÑÁ¹éÓ˹ѡμÑÇ/Çѹ) »ÃÔÁÒ³¡ÒúÃÔâÀ¤ÍÒËÒÃá싧ÊÕ (¡ÔâÅ¡ÃÑÁ/¤¹/Çѹ) »ÃÔÁÒ³ÊÕÊѧà¤ÃÒÐˏ·Õ辺ã¹ÍÒËÒà (ÁÔÅÅÔ¡ÃÑÁ/¡ÔâÅ¡ÃÑÁ) ¹éÓ˹ѡμÑÇ (body weight) ¢Í§¡ÅØ‹ÁμÑÇÍ‹ҧ (¡ÔâÅ¡ÃÑÁ)

»ÃÐàÁÔ ¹ ¡ÒÃä´Œ ÃÑ º ÊÑ Á ¼Ñ Ê ÊÕ ÊÑ § à¤ÃÒÐˏ á μ‹ Å Ðª¹Ô ´ ¨Ò¡·Ø ¡ ÃÒ¡ÒÃÍÒËÒ÷Õè º ÃÔ â À¤ â´Â¡ÒäӹdzËÒ¤‹ Ò Total exposure ¢Í§ÊÕ ª ¹Ô ´ ¹Ñé ¹ æ «Öè § ä´Œ Á Ò¨Ò¡¡ÒÃÃÇÁ¤‹ Ò Exposure ·Õè¤Ó¹Ç³ä´Œ¨Ò¡ÍÒËÒÃáμ‹ÅÐÃÒ¡Òà áÅйÓä» ¤Ó¹Ç³ËÒÅѡɳТͧ¤ÇÒÁàÊÕè§ (risk) â´Âà»ÃÕºà·Õº »ÃÔÁÒ³¡ÒÃä´ŒÃѺÊÑÁ¼ÑÊ·Ñé§ËÁ´ (total exposure) ¢Í§ÊÕª¹Ô´ ¹Ñ鹡Ѻ¤‹Ò Acceptable Daily Intake (ADI) ¢Í§ÊÕáμ‹ÅÐ ª¹Ô´ â´Â¤Ó¹Ç¹à»š¹ÃŒÍÂÅТͧ¤‹Ò ADI ´Ñ§ÊÁ¡ÒÃ

»Ãاá싧 âÂà¡ÔÏμ»Ãاá싧 äÍÈ¡ÃÕÁ¹Á ໚¹μŒ¹ ʋǹÍÒËÒà ¨Ò¹à´Õ  ǷÕè ¾ º¡ÒûÃØ § áμ‹ § ÊÕ «Öè § ໚ ¹ ·Õè ¹Ô Â ÁºÃÔ â À¤¢Í§à´ç ¡ 䴌ᡋ àÂç¹μÒâ¿ ¢ŒÒÇËÁ¡ä¡‹ ¢ŒÒÇËÁÙá´§ ໚¹μŒ¹ ¨Ö§·Ó¡Òà ÊØ‹Áà¡çºμÑÇÍ‹ҧÍÒËÒ÷Õèà´ç¡¹Ñ¡àÃÕ¹¹ÔÂÁºÃÔâÀ¤μÒÁࡳ±·Õè ÇÒ§äÇŒ ໚¹ÍÒËÒ÷Ñé§ËÁ´ 75 ÃÒ¡Òà ¨Ò¡ 13 ¡ÅØ‹ÁÍÒËÒà ¼Å¡ÒÃÇÔà¤ÃÒÐˏª¹Ô´áÅлÃÔÁÒ³ÊÕÊѧà¤ÃÒÐˏã¹ÍÒËÒÃàËÅ‹Ò¹Õé ¾ºÇ‹ÒÍÒËÒÃËÅÒÂÃÒ¡ÒÃÁÕ¡ÒÃ㪌ÊÕÊѧà¤ÃÒÐˏ»Ãاá싧ÍÒËÒà â´Â¾ºÊÕÊѧà¤ÃÒÐˏ·Ñé§ËÁ´ 7 ª¹Ô´ ¡ÅØ‹ÁÊÕá´§ 䴌ᡋ »Í§â«

Risk = Total exposure X 100 ADI ¶ŒÒ Risk > 100% of ADI áÊ´§Ç‹ÒÁÕ¤ÇÒÁàÊÕè§μ‹ÍÊØ¢ÀÒ¾¼ÙŒä´ŒÃѺÊÑÁ¼ÑÊ °“√«‘‡§√“–Àå∑“ß ∂‘μ‘

ÊÕÊѧà¤ÃÒÐˏ¼ÊÁÍÒËÒÃáμ‹ÅЪ¹Ô´·ÕèμÃǨ¾ºã¹ÍÒËÒ÷Õè ¹Ñ¡àÃÕ¹ºÃÔâÀ¤áÊ´§¤‹Ò໚¹ÃŒÍÂÅТͧμÑÇÍ‹ҧÍÒËÒ÷ÕèμÃǨ ÇÔà¤ÃÒÐˏ·Ñé§ËÁ´ áÅФÇÒÁࢌÁ¢Œ¹¢Í§ÊÕÊѧà¤ÃÒÐˏã¹ÍÒËÒ÷Õè ºÃÔâÀ¤áÊ´§à»š¹¤‹ÒÊÙ§ÊØ´áÅФ‹ÒμèÓÊØ´ ʋǹ»ÃÔÁÒ³¡ÒÃä´ŒÃѺ ÊÑÁ¼ÑÊÊÕÊѧà¤ÃÒÐˏ¼ÊÁÍÒËÒèҡ¡ÒúÃÔâÀ¤ÍÒËÒ÷ÕèÃдѺ ¡ÒúÃÔâÀ¤à©ÅÕè áÅÐÃдѺ¡ÒúÃÔâÀ¤·Õè 97.5 à»ÍÏà«ç¹ä·Å áÊ´§à»š¹ÃŒÍÂÅТͧ¤‹Ò ADI º≈°“√∑¥≈Õß

¼Å¡ÒÃÈÖ¡ÉÒ¾ºÇ‹ÒÍÒËÒüÊÁÊÕ¡ÅØ‹Á·Õèà´ç¡¹Ñ¡àÃÕ¹¹ÔÂÁ ºÃÔâÀ¤ã¹»ÃÔÁÒ³áÅФÇÒÁ¶Õè·ÕèÊÙ§ 3 Íѹ´Ñºáá ¤×Í ¡ÅØ‹Á

4 ÍÒÏ, ¤ÒÏâÁÍÕ«Õ¹ áÅÐàÍÍÃÔâ¸Ã«Õ¹ ¡ÅØ‹ÁÊÕàËÅ×ͧ 䴌ᡋ «Ñ¹à«çμ àÂçÅâÅǏ àÍç¿«ÕàÍç¿ áÅÐμÒÏμÃÒ«Õ¹ ¡ÅØ‹ÁÊÕ¹éÓà§Ô¹ 䴌ᡋ ºÃÔÅàÅÕ¹· ºÅÙ àÍç¿«ÕàÍç¿ áÅÐÍÔ¹´Ôâ¡μÔ¹ ÊÕà¢ÕÂÇ ä´Œá¡‹ ¿ÒÊμ ¡ÃÕ¹ àÍç¿«ÕàÍç¿ ÊÕÊѧà¤ÃÒÐˏ·Ñé§ËÁ´·Õ辺㹠ÍÒËÒèѴ໚¹ª¹Ô´ÊÕ·Õè¡ÃзÃǧÊÒ¸ÒóÊآ͹ØÞÒμãˌ㪌㹠ÍÒËÒà (μÒÃÒ§·Õè 2) àÁ×è;ԨÒóҪ¹Ô´ÊÕ·Õ辺ã¹ÍÒËÒþºÇ‹Ò ÊÕ㹡ÅØ‹ÁÊÕàËÅ×ͧ ¤×Í μÒÏμÃÒ«Õ¹ áÅÐ «Ñ¹à«çμ àÂçÅâÅǏ àÍç¿ «ÕàÍç¿ à»š¹ÊÕÊѧà¤ÃÒÐˏ¼ÊÁÍÒËÒ÷Õè¹ÔÂÁ㪌ÁÒ¡·ÕèÊØ´ Ãͧŧ ÁÒ ¤×Í ¡ÅØ‹ÁÊÕá´§ 䴌ᡋ ¤ÒÏâÁÍÕ«Õ¹ áÅлͧ⫠4 ÍÒÏ 㹡ÒÃÈÖ¡ÉÒ¹Õ龺¡ÒÃ㪌ÊÕÊѧà¤ÃÒÐˏ¼ÊÁÍÒËÒÃã¹»ÃÔÁÒ³ÊÙ§ à¡Ô¹¤‹Ò·Õè¡®ËÁÒ¡Ó˹´à¾Õ§ÌÍÂÅÐ 9 ¢Í§¨Ó¹Ç¹μÑÇÍ‹ҧ ÍÒËÒ÷Ñé§ËÁ´ áμ‹¾º¡ÒÃ㪌ÊÕÊѧà¤ÃÒÐˏã¹ÍÒËÒ÷ÕèäÁ‹Í¹ØÞÒμ ªï∑’Ë 43 ©∫—∫∑’Ë 4 μÿ≈“§¡ - ∏—𫓧¡ 2551

R1_Nutrition_p28-37_pro1.indd Sec1:33

33

6/22/09 11:04:52 PM


ãËŒãÊ‹ÊÕËÅÒÂÃÒ¡Òà 䴌ᡋ äÊŒ¡ÃÍ¡ ÅÙ¡ªÔé¹ à¡ÕêÂÇ·Í´ ºÐËÁÕèàËÅ×ͧ ºÐËÁÕèË¡ ¢ŒÒÇËÁ¡ä¡‹ ¢¹Á¨Õº áÅнÃÑè§áª‹ºÇ ¡Òäӹdz»ÃÔÁÒ³¡ÒÃä´ŒÃѺÊÑÁ¼ÑÊÊÕÊѧà¤ÃÒÐˏ¼ÊÁÍÒËÒà áμ‹ÅЪ¹Ô´ã¹¡ÅØ‹Á»ÃЪҡ÷Ñé§ËÁ´ (μÒÃÒ§·Õè 3) ¾ºÇ‹Ò¡Òà 䴌ÃѺÊÑÁ¼ÑÊÊÕÊѧà¤ÃÒÐˏ¼ÊÁÍÒËÒÃËÅÒª¹Ô´¢Í§à´ç¡¹Ñ¡àÃÕ¹ ã¹¾×é¹·Õ誹º·¢Í§¨Ñ§ËÇÑ´¹¤Ã»°ÁÁÕ¤‹ÒÊÙ§¡Ç‹Òà´ç¡¹Ñ¡àÃÕ¹㹠¾×é¹·ÕèàÁ×ͧ¢Í§¡Ãا෾ÁËÒ¹¤Ã àÁ×èÍ»ÃÐàÁÔ¹¤ÇÒÁàÊÕ觢ͧ ¡ÒÃä´ŒÃѺÊÑÁ¼ÑÊà»ÃÕºà·Õº¡Ñº¤‹Ò ADI ¢Í§ÊÕª¹Ô´¹Ñé¹ ¾ºÇ‹Ò à´ç ¡ ÃÐ´Ñ º »ÃжÁÈÖ ¡ ÉÒÁÕ ¡ ÒÃä´Œ ÃÑ º ÊÑ Á ¼Ñ Ê ÊÕ ¨ Ò¡¡ÒúÃÔ â À¤ ÍÒËÒ÷ÕèÁÕÊÕÊѧà¤ÃÒÐˏã¹ÃдѺ¤ÇÒÁàÊÕ觷ÕèÊÙ§¡Ç‹Òà´ç¡ÃдѺ ÁѸÂÁÈÖ¡ÉÒã¹·Ñé§Êͧ¾×é¹·ÕèÈÖ¡ÉÒ ÊÕ·ÕèÁÕ¤‹Òà©ÅÕè¢ͧ»ÃÔÁÒ³¡Òà 䴌ÃѺÊÑÁ¼ÑÊàÁ×èÍà»ÃÕºà·Õº¡Ñº¤‹Ò ADI ÊÙ§¡Ç‹ÒÊÕÍ×è¹ ã¹¡ÅØ‹Á ¢Í§à´ç¡¹Ñ¡àÃÕ¹ÃдѺ»ÃжÁáÅÐÁѸÂÁÈÖ¡ÉҢͧ¡Ãا෾ÁËÒ¹¤Ã ¤×Í ¤ÒÏâÁÍÕ«Õ¹ «Öè§ÁÕ¤‹Òà¾Õ§ÌÍÂÅÐ 5 áÅÐ 3 ¢Í§¤‹Ò ADI μÒÁÅӴѺ ¢³Ð·Õè㹡ÅØ‹Á¢Í§à´ç¡¹Ñ¡àÃÕ¹ÃдѺ »ÃжÁáÅÐÁѸÂÁÈÖ¡ÉҢͧ¨Ñ§ËÇÑ´¹¤Ã»°Á ¤×Í àÍÍÃÔâ¸Ã«Õ¹ «Öè§ÁÕ¤‹Ò෋ҡѺ ÃŒÍÂÅÐ 25 áÅÐ 16 ¢Í§¤‹Ò ADI μÒÁÅӴѺ ¢³Ð·Õè¡ÒÃä´ŒÃѺÊÑÁ¼ÑÊÊիѹà«çμ àÂçÅâÅǏ ÁÕ¤ÇÒÁàÊÕè§μ‹Í¡ÒÃä´Œ ÃѺÊÑÁ¼ÑÊμÒÁÁÒ໚¹Íѹ´Ñº·Õè 2 ã¹·Ñé§Êͧ¾×é¹·ÕèÈÖ¡ÉÒ â´Â »ÃÔÁÒ³¡ÒÃä´ŒÃѺÊÑÁ¼ÑÊÊÕÊѧà¤ÃÒÐˏ·Ø¡ª¹Ô´àÁ×èÍ»ÃÐàÁÔ¹·ÕèÃдѺ à©ÅÕè¢ͧ¡ÒúÃÔâÀ¤ÍÒËÒÃÁÕ¤‹ÒμèÓ¡Ç‹Ò¤‹Ò ADI μÒÃÒ§·Õè 2

«‘®“√≥åº≈°“√»÷°…“

¡ÒûÃÐàÁԹʶҹ¡Òó¡ÒÃ㪌ÊÕÊѧà¤ÃÒÐˏã¹ÍÒËÒ÷Õèà´ç¡ ¹Ñ¡àÃÕ¹¹ÔÂÁºÃÔâÀ¤ äÁ‹¾º¡ÒÃ㪌ÊÕÊѧà¤ÃÒÐˏª¹Ô´·Õè¡ÃзÃǧ ÊÒ¸ÒóÊØ ¢äÁ‹ Í ¹Ø Þ ÒμãËŒ ã ªŒ ã ¹ÍÒËÒà áμ‹ ¾ º¡ÒÃ㪌 ÊÕ ã ¹ »ÃÔÁÒ³ÊÙ§à¡Ô¹¤‹Ò·Õè¡®ËÁÒ¡Ó˹´ áÅÐÁÕ¡ÒÃ㪌ÊÕÊѧà¤ÃÒÐˏ ¼ÊÁÍÒËÒÃã¹ÍÒËÒ÷ÕèäÁ‹Í¹ØÞÒμãˌ㪌ÊÕËÅÒÂÃÒ¡Òà áÊ´§ Ç‹Ò¡ÒäǺ¤ØÁ¡ÒÃ㪌ÊÕã¹ÍÒËÒùÑé¹ÂѧμŒÍ§ÁÕ¡ÒûÃЪÒÊÑÁ¾Ñ¹¸ ãËŒ¼ÙŒ¼ÅÔμࢌÒã¨ÇÔ¸Õ¡ÒÃ㪌ÊÕ¼ÊÁÍÒËÒ÷Õè¶Ù¡μŒÍ§ áÅÐμŒÍ§ÁÕ¡Òà ཇÒÃÐÇѧ¡ÒùÓÊÕÊѧà¤ÃÒÐˏ¼ÊÁÍÒËÒÃ仼ÊÁã¹ÍÒËÒ÷ÕèäÁ‹ ͹ØÞÒμãËŒãÊ‹ÊÕ àÁ×èÍ»ÃÐàÁÔ¹¤ÇÒÁàÊÕ觢ͧ¡ÒÃä´ŒÃѺÊÑÁ¼ÑÊÊÕÊѧà¤ÃÒÐˏ¼ÊÁ ÍÒËÒÃã¹à´ç¡¹Ñ¡àÃÕ¹ â´Â¡ÒÃà»ÃÕºà·Õº»ÃÔÁÒ³¡ÒÃä´ŒÃѺ ÊÑÁ¼ÑÊÊաѺ¤‹Ò ADI ¾ºÇ‹ÒÁÕ¤ÇÒÁáμ¡μ‹Ò§¡Ñ¹ã¹ 2 ¾×é¹·Õè ÈÖ¡ÉÒ â´Âà´ç¡¹Ñ¡àÃÕ¹㹾×é¹·Õèà¢μª¹º·¢Í§¹¤Ã»°Á¨Ðä´ŒÃѺ ÊÑÁ¼ÑÊÊÕËÅÒª¹Ô´ã¹ÃдѺ¢Í§¤ÇÒÁàÊÕ觷ÕèÊÙ§¡Ç‹Òà´ç¡¹Ñ¡àÃÕ¹ ã¹¾×é¹·Õèà¢μàÁ×ͧ¢Í§¡Ãا෾ÁËÒ¹¤Ã ÊÓËÃѺà´ç¡¹Ñ¡àÃÕ¹㹠¡Ãا෾ÁËÒ¹¤Ã¹Ñé¹ ÊÕ¤ÒÏâÁÍÕ«Õ¹ (ÊÕá´§) ¨Ð໚¹ÊÕ·Õè¡‹ÍãËŒ à¡Ô´¤ÇÒÁàÊÕ觨ҡ¡ÒÃä´ŒÃѺÊÑÁ¼ÑÊÊÙ§¡Ç‹ÒÊÕÊѧà¤ÃÒÐˏª¹Ô´Í×è¹ à¹×è Í §¨Ò¡à»š ¹ ÊÕ ·Õè ÁÕ » ÃÔ Á Ò³¡ÒÃ㪌 ÊÙ §ã¹ÍÒËÒÃËÅÒª¹Ô ´ ·Õè à´ç¡¡ÅØ‹Á¹Õé¹ÔÂÁºÃÔâÀ¤ â´Â੾ÒÐÍÒËÒÃ㹡ÅØ‹Áà¤Ã×èͧ´×èÁ áμ‹

»ÃÔÁÒ³ÊÕÊѧà¤ÃÒÐˏ¼ÊÁÍÒËÒ÷Õ辺ã¹ÍÒËÒ÷Õèà´ç¡¹Ñ¡àÃÕ¹¹ÔÂÁºÃÔâÀ¤*

ª¹Ô´ÊÕÊѧà¤ÃÒÐˏ·Õè͹ØÞÒμ ãˌ㪌ã¹ÍÒËÒÃ

ÃŒÍÂÅТͧμÑÇÍ‹ҧÍÒËÒ÷Õ辺ÊÕ

¤ÇÒÁࢌÁ¢Œ¹¢Í§ÊÕÊѧà¤ÃÒÐˏ (Á¡./¡¡.) ¹¤Ã»°Á ¡Ãا෾ÁËÒ¹¤Ã

¡Ãا෾ÁËÒ¹¤Ã

¹¤Ã»°Á

¤ÒÏâÁÍÕ«Õ¹

25

31

0.88 - 64.29

0.08 - 87.06

»Í§â« 4 ÍÒÏ

26

24

0.36- 53.02

0.23 - 62.65

àÍÍÃÔâ¸Ã«Õ¹

8

14

0.09- 1.46

1.01 - 26.13

μÒÏμÃÒ«Õ¹

40

45

0.45 - 84.87

0.21 - 81.43

«Ñ¹à«çμ àÂçÅâÅǏ àÍç¿«ÕàÍç¿

30

36

0.92 - 53.08

0.80 - 78.05

ºÃÔÅàÅÕ¹· ºÅÙ àÍç¿«ÕàÍç¿

20

16

0.19 - 3.70

0.13 - 3.70

¿ÒÊμ ¡ÃÕ¹ àÍç¿«ÕàÍç¿

3

5

4.57 - 4.70

0.78 - 5.14

* ¨Ó¹Ç¹μÑÇÍ‹ҧÍÒËÒ÷ÕèμÃǨÇÔà¤ÃÒÐˏ·Ñé§ËÁ´ 75 ÃÒ¡ÒÃ

34

«“√ “√‚¿™π“°“√

R1_Nutrition_p28-37_pro1.indd Sec1:34

6/22/09 11:04:52 PM


μÒÃÒ§·Õè 3

»ÃÔÁÒ³¡ÒÃä´ŒÃѺÊÑÁ¼ÑÊÊÕÊѧà¤ÃÒÐˏ¼ÊÁÍÒËÒ÷ÕèÃдѺà©ÅÕè áÅÐ 97.5 à»ÍÏà«ç¹ä·Å ¨Ò¡¡ÒúÃÔâÀ¤ÍÒËÒà 㹡ÅØ‹Á»ÃЪҡ÷Ñé§ËÁ´ (per capita)*

¡ÅØ‹ÁÍÒÂØ

»ÃÔÁÒ³¡ÒÃä´ŒÃѺÊÑÁ¼ÑÊ·Ñé§ËÁ´ (%ADI)

ª¹Ô´ÊÕÊѧà¤ÃÒÐˏ

¾×é¹·Õèà¢μª¹º·¢Í§¹¤Ã»°Á

¾×é¹·Õèà¢μàÁ×ͧ¢Í��¡Ãا෾ÁËÒ¹¤Ã

·ÕèÃдѺà©ÅÕèÂ

·ÕèÃдѺ 97.5 à»ÍÏà«ç¹ä·Å

·ÕèÃдѺà©ÅÕèÂ

·ÕèÃдѺ 97.5 à»ÍÏà«ç¹ä·Å

ªÑé¹»ÃжÁÈÖ¡ÉÒ ¤ÒÏâÁÍÕ«Õ¹

7.213

37.395

5.089

26.248

(ÍÒÂØ 7-12 »‚)

»Í§â« 4 ÍÒÏ

0.708

3.653

1.259

6.615

àÍÍÃÔâ¸Ã«Õ¹

25.070

130.539

1.320

7.081

μÒÏμÃÒ«Õ¹

2.201

10.638

0.968

4.633

«Ñ¹à«çμ àÂçÅâÅǏ àÍç¿«ÕàÍç¿

7.390

43.003

2.351

13.590

ºÃÔÅàÅÕ¹· ºÅÙ àÍç¿«ÕàÍç¿

0.022

0.022

0.018

0.084

¿ÒÊμ ¡ÃÕ¹ àÍç¿«ÕàÍç¿

0.007

0.040

0.004

0.020

¤ÒÏâÁÍÕ«Õ¹

5.295

26.618

3.151

19.299

0.767

3.539

0.903

5.292

àÍÍÃÔâ¸Ã«Õ¹

15.834

80786

1.121

6.727

μÒÏμÃÒ«Õ¹

3.135

10.114

1.200

6.068

«Ñ¹à«çμ àÂçÅâÅǏ àÍç¿«ÕàÍç¿

5.725

30.445

2.314

12.719

ºÃÔÅàÅÕ¹· ºÅÙ àÍç¿«ÕàÍç¿

0.013

0.063

0.017

0.073

¿ÒÊμ ¡ÃÕ¹ àÍç¿«ÕàÍç¿

0.021

0.102

0.006

0.034

ªÑé¹ÁѸÂÁÈÖ¡ÉÒ

(ÍÒÂØ 13-18 »‚) »Í§â« 4 ÍÒÏ

* ¨Ó¹Ç¹¡ÅØ‹ÁμÑÇÍ‹ҧ·Ñé§ËÁ´ 400 ¤¹ ẋ§à»š¹ 100 ¤¹/ÃдѺªÑé¹/¾×é¹·Õè à´ç ¡ ¹Ñ ¡ àÃÕ Â ¹ã¹¨Ñ § ËÇÑ ´ ¹¤Ã»°Á¹Ñé ¹ ¡ÅÑ º ¾ºÇ‹ Ò ÊÕ à ÍÍÃÔ â ¸Ã«Õ¹ (ÊÕá´§) ໚¹ÊÕ·Õè¡‹ÍãËŒà¡Ô´¤ÇÒÁàÊÕ觨ҡ¡ÒÃä´ŒÃѺÊÑÁ¼ÑÊÊÙ§¡Ç‹Ò ÊÕª¹Ô´Í×è¹ áÁŒ¨ÐÁÕ»ÃÔÁÒ³¡ÒÃ㪌ã¹ÍÒËÒÃμèÓ¡Ç‹ÒÊÕ¤ÒÏâÁÍÕ«Õ¹ à¹×èͧ¨Ò¡à»š¹ÊÕ·ÕèÁÕ¤‹Ò ADI μèÓ àÁ×èÍà»ÃÕºà·Õº»ÃÔÁÒ³¡ÒÃä´Œ ÃѺÊÑÁ¼ÑʡѺ¤‹Ò ADI ¨Ö§¡‹ÍãËŒà¡Ô´¤ÇÒÁàÊÕè§μ‹Í¡ÒÃä´ŒÃѺ ÊÑÁ¼ÑÊã¹ÃдѺ·ÕèÊÙ§¡Ç‹ÒÊÕÍ×è¹ Í‹ҧäáçμÒÁ»ÃÔÁÒ³ ¡ÒÃä´ŒÃѺÊÕÊѧà¤ÃÒÐˏ·Ñé§ 7 ª¹Ô´·Õ辺ã¹ÍÒËÒëÖè§à´ç¡ ¹Ñ¡àÃÕ¹·Ñé§ 2 ¾×é¹·Õè¹ÔÂÁºÃÔâÀ¤ àÁ×èÍ»ÃÐàÁÔ¹·ÕèÃдѺà©ÅÕè¢ͧ ¡ÒÃä´ŒÃѺÊÑÁ¼ÑÊÂѧÁÕ¤‹ÒμèÓ¡Ç‹Ò¤‹Ò ADI ÁÒ¡ ¨Ö§¶×ÍÇ‹Ò¤ÇÒÁ àÊÕ觷Õ辺äÁ‹ÁÕ¹ÑÂÊÓ¤ÑÞ·Õè¨Ð¡‹ÍãËŒà¡Ô´¼ÅàÊÕÂμ‹ÍÊØ¢ÀÒ¾ ´Ñ§¹Ñé¹ ã¹¡ÒúÃÔâÀ¤ÍÒËÒ÷ÕèÁÕÊբͧà´ç¡¹Ñ¡àÃÕ¹㹠2 ¾×é¹·Õè¹Õé àÁ×èÍ »ÃÐàÁÔ¹·ÕèÃдѺà©ÅÕè¢ͧ¡ÒúÃÔâÀ¤·ÑèÇ仹Ñé¹ äÁ‹¡‹ÍãËŒà¡Ô´

¤ÇÒÁàÊÕè  §μ‹ Í ¡ÒÃä´Œ ÃÑ º ÊÕ ÊÑ § à¤ÃÒÐˏ ã ¹»ÃÔ Á Ò³·Õè · ÓãËŒ à ¡Ô ´ ÍѹμÃÒÂμ‹ÍÊØ¢ÀÒ¾¼ÙŒºÃÔâÀ¤ ËÒ¡»ÃÐàÁÔ¹ã¹ÃдѺ¡ÒúÃÔâÀ¤·ÕèÊ٧ઋ¹·ÕèÃдѺ 97.5 à»ÍÏà«ç¹μä·´ ¾ºÇ‹Ò¤ÇÒÁàÊÕè§㹡ÒÃä´ŒÃѺàÍÍÃÔâ¸Ã«Õ¹¨Ò¡ ¡ÒúÃÔ â À¤ÍÒËÒÃ㹡ÅØ‹ Á à´ç ¡ ¹Ñ ¡ àÃÕ Â ¹·Ñé § ÃÐ´Ñ º »ÃжÁáÅÐ ÁѸÂÁÈÖ¡ÉÒ㹨ѧËÇÑ´¹¤Ã»°ÁÊÙ§¢Öé¹à»š¹ÃŒÍÂÅÐ 131 áÅÐ 81 ¢Í§ ADI μÒÁÅӴѺ áÊ´§Ç‹Ò¶ŒÒ»ÃÐàÁԹŧä»ã¹¡ÅØ‹Áà´ç¡ ¹Ñ¡àÃÕ¹·ÕèºÃÔâÀ¤ÍÒËÒÃã¹ÃÒ¡Ò÷Õ辺NjÒÁÕ¡ÒÃ㪌àÍÍÃÔâ¸Ã«Õ¹ ·Ø¡ÃÒ¡ÒÃã¹»ÃÔÁÒ³¡ÒúÃÔâÀ¤·ÕèÊÙ§ ¨Ð·ÓãËŒ»ÃÔÁÒ³¡ÒÃä´Œ ÃÑ º ÊÑ Á ¼Ñ Ê ÊÕ ¹Õé¨ Ò¡¡ÒúÃÔ â À¤ÍÒËÒÃ㹡ÅØ‹ Á ¢Í§à´ç ¡ ¹Ñ ¡ àÃÕ Â ¹ ÃдѺ»ÃжÁÈÖ¡ÉÒÊÙ§¡Ç‹Ò¤‹Ò ADI ªï∑’Ë 43 ©∫—∫∑’Ë 4 μÿ≈“§¡ - ∏—𫓧¡ 2551

R1_Nutrition_p28-37_pro1.indd Sec1:35

35

6/22/09 11:04:52 PM


¶ŒÒ¾Ô¨ÒóÒ໚¹¡ÒúÃÔâÀ¤ÍÒËÒÃáμ‹ÅÐÃÒ¡ÒèоºÇ‹Ò ÃÒ¡ÒÃÍÒËÒ÷Õè·ÓãËŒ»ÃÔÁÒ³¡ÒÃä´ŒÃѺÊÑÁ¼ÑÊÊÕ¹Õé·ÕèÃдѺ 97.5 à»ÍÏà«ç¹μä·´ Ê٧໚¹Íѹ´Ñº 1 ¤×Í äÊŒ¡ÃÍ¡ â´ÂÁÕ¤‹ÒÊÙ§¶Ö§ ÃŒÍÂÅÐ 71 ¢Í§ ADI ÃͧŧÁÒ¤×Í ÅÙ¡ªÔé¹ «Öè§ÁÕ¤‹Ò෋ҡѺ ÃŒÍÂÅÐ 37 ¢Í§ ADI áμ‹ã¹¤ÇÒÁ໚¹¨ÃÔ§ã¹áμ‹ÅÐÇѹ¹Ñé¹ ¼ÙŒºÃÔâÀ¤Ë¹Ö觤¹¨ÐäÁ‹ÊÒÁÒöºÃÔâÀ¤ÍÒËÒÃã¹»ÃÔÁÒ³Ê٧䴌 ËÅÒÂÃÒ¡Òà ´Ñ§¹Ñ鹤‹Ò·Õè»ÃÐàÁÔ¹¨Ò¡¡ÒúÃÔâÀ¤ÍÒËÒ÷Ñé§ËÁ´ ·ÕèÃдѺ 97.5 à»ÍÏà«ç¹μä·´¢Í§¡ÒÃä´ŒÃѺÊÑÁ¼Ñʨҡ·Ø¡ÃÒ¡Òà ÍÒËÒËÍÁ໚¹¤‹Ò¡ÒûÃÐàÁÔ¹·ÕèÊÙ§¡Ç‹Ò¤ÇÒÁ໚¹¨ÃÔ§ á싶ŒÒ ¤Ó¹Ç³â´Â㪌»ÃÔÁÒ³¡ÒúÃÔâÀ¤ÍÒËÒ÷Õè 97.5 à»ÍÏà«ç¹μä·´ ÊÓËÃѺ 2 ÃÒ¡ÒÃáá·ÕèÁÕ¡ÒÃä´ŒÃѺÊÑÁ¼ÑÊÊÙ§ÊØ´ ¾ºÇ‹Ò»ÃÔÁÒ³ ¡ÒÃä´ŒÃѺÊÕàÍÍÃÔâ¸Ã«Õ¹¨Ò¡¡ÒúÃÔâÀ¤ÍÒËÒÃà¾Õ§ 2 ÃÒ¡Òà ¤×Í äÊŒ¡ÃÍ¡ áÅÐÅÙ¡ªÔé¹ ã¹»ÃÔÁÒ³¡ÒúÃÔâÀ¤ÊÙ§·ÕèÃдѺ 97.5 à»ÍÏà«ç¹μä·´ ¨Ð·ÓãËŒ»ÃÔÁÒ³¡ÒÃä´ŒÃѺÊÑÁ¼ÑÊÊÕ¹ÕéÁÕ¤‹ÒÊÙ§à¡Ô¹ ¤‹Ò ADI (ÃŒÍÂÅÐ 108 ¢Í§ ADI) áÊ´§Ç‹Ò¶ŒÒà´ç¡¡ÅØ‹Á¹ÕéÁÕ¡Òà ºÃÔâÀ¤äÊŒ¡ÃÍ¡áÅÐÅÙ¡ªÔé¹ã¹»ÃÔÁÒ³ÊÙ§ áÅжŒÒÍÒËÒùÑé¹ÂѧÁÕ ¡ÒÃ㪌ÊÕ¹Õéã¹ÃдѺÊÙ§ ÍҨʋ§¼ÅãËŒà¡Ô´¤ÇÒÁàÊÕè§μ‹Í¡ÒÃä´ŒÃѺ ÊÑÁ¼ÑÊÊÕàÍÍÃÔâ¸Ã«Õ¹ã¹»ÃÔÁÒ³·ÕèÊ‹§¼ÅàÊÕÂμ‹ÍÊØ¢ÀҾ䴌 «Öè§μÒÁ »ÃСÒȢͧ¡ÃзÃǧÊÒ¸ÒóÊØ¢¹Ñé¹ ÍÒËÒûÃÐàÀ·äÊŒ¡ÃÍ¡ áÅÐÅÙ¡ªÔ鹨Ѵ໚¹ÍÒËÒ÷ÕèäÁ‹Í¹ØÞÒμãËŒãÊ‹ÊÕÊѧà¤ÃÒÐˏ㹡Òà ¼ÅÔ μ ¨Ö § ¤ÇÃÁÕ ¡ ÒÃཇ Ò ÃÐÇÑ § ·Õè à ¢Œ Á §Ç´à¾×è ÍäÁ‹ ã ËŒ à ¡Ô ´ ¡ÒùÓÊÕ Êѧà¤ÃÒÐˏ¼ÊÁÍÒËÒÃÁÒ㪌ã¹ÍÒËÒÃËŒÒÁãÊ‹ÊÕ â´Â੾ÒÐÍÒËÒà ·Õèà´ç¡¹ÔÂÁºÃÔâÀ¤ã¹»ÃÔÁÒ³ÊÙ§ ઋ¹ äÊŒ¡ÃÍ¡ áÅÐÅÙ¡ªÔé¹ ¨Ö§¨Ð ·ÓãËŒÊÒÁÒöŴ¤ÇÒÁàÊÕ觢ͧ¡ÒÃä´ŒÃѺÊÑÁ¼ÑÊÊÕÊѧà¤ÃÒÐˏ¹Õé ŧä»ä´Œ ¨Ò¡¡ÒÃÈÖ ¡ ÉÒ¹Õé á ÅСÒÃÈÖ ¡ ÉÒ·Õè ¼‹ Ò ¹ÁÒ ¾ºÇ‹ Ò ¡ÒÃ㪌 ÊÕÊѧà¤ÃÒÐˏ¡ÅØ‹ÁÊÕá´§áÅÐÊÕàËÅ×ͧ໚¹ÊÒàËμØÊÓ¤ÑÞ·Õè·ÓãËŒà´ç¡ ä´ŒÃѺÊÕÊѧà¤ÃÒÐˏ¨Ò¡¡ÒúÃÔâÀ¤ÍÒËÒà ¡ÒûÃÐàÁÔ¹¤ÇÒÁàÊÕè§ 㹡ÅØ‹Á»ÃЪҡÃÍÒÂØ 3-14 »‚ ã¹»ÃÐà·ÈºÃÒ«ÔÅ »‚ ¤.È. 199213 ¾ºÇ‹ÒÊÕ·ÕèÁÕ¤‹Òà©ÅÕè¢ͧ»ÃÔÁÒ³¡ÒÃä´ŒÃѺÊÑÁ¼ÑÊ·ÕèÁÕ¤ÇÒÁàÊÕè§ ÊÙ§ÊØ´ ¤×Í Amaranth «Öè§à»š¹ÊÕ㹡ÅØ‹ÁÊÕá´§ â´ÂÁÕ¤‹ÒÊÙ§¶Ö§ ÃŒÍÂÅÐ 24 ¢Í§ ADI ÃͧŧÁÒ ¤×Í «Ñ¹à«çμ àÂçÅâÅǏ àÍç¿«ÕàÍç¿ (ÃŒÍÂÅÐ 3.0 ¢Í§ ADI) «Öè§à»š¹ÊÕ㹡ÅØ‹ÁÊÕàËÅ×ͧ μÒÁ´ŒÇ ÊÕá´§ ¤×Í »Í§â« 4 ÍÒÏ (ÃŒÍÂÅÐ 0.4 ¢Í§ ADI) áÅСÒà ÈÖ ¡ ÉÒ㹡ÅØ‹ Á »ÃЪҡÃÍÒÂØ 6-18 »‚ ã¹»ÃÐà·ÈÍÔ ¹ à´Õ  »‚ ¤.È. 200314 ¾ºÇ‹ÒÊÕ·ÕèÁÕ¤‹Òà©ÅÕè¢ͧ»ÃÔÁÒ³¡ÒÃä´ŒÃѺÊÑÁ¼ÑÊ ·ÕèÁÕ¤ÇÒÁàÊÕè§ÊÙ§ÊØ´ ¤×Í àÍÍÃÔâ¸Ã«Õ¹ (ÃŒÍÂÅÐ 10 ¢Í§ ADI) «Öè§à»š¹ÊÕ㹡ÅØ‹ÁÊÕá´§ ÃͧŧÁÒ ¤×Í «Ñ¹à«çμ àÂçÅâÅǏ àÍç¿«ÕàÍç¿ (ÃŒÍÂÅÐ 9.6 ¢Í§ ADI) áÅÐμÒÏμÃÒ«Õ¹ (ÃŒÍÂÅÐ 6.4 ¢Í§ ADI) «Öè§à»š¹ÊÕ㹡ÅØ‹ÁÊÕàËÅ×ͧ ´Ñ§¹Ñ鹤ÇÃÁÕÁÒμáÒÃࢌÁ§Ç´ã¹ 36

¡ÒäǺ¤ØÁáÅÐཇÒÃÐÇѧ¤Ø³ÀÒ¾áÅлÃÔÁÒ³¡ÒÃ㪌ÊÕàËÅ‹Ò¹Õéã¹ ÍÒËÒÃÊÓËÃѺà´ç¡ â´Â੾ÒÐÊÕÊѧà¤ÃÒÐˏ㹡ÅØ‹ÁÊÕá´§ ઋ¹ àÍÍÃÔ â ¸Ã«Õ ¹ «Öè § ໚ ¹ ÊÕ ÊÑ § à¤ÃÒÐˏ ·Õè ÁÕ ¤‹ Ò ADI μè Ó áÅÐ ÊÕÊѧà¤ÃÒÐˏ㹡ÅØ‹ÁÊÕàËÅ×ͧ ઋ¹ «Ñ¹à«çμ àÂçÅâÅǏ àÍç¿«ÕàÍç¿ áÅÐμÒÏμÃÒ«Õ¹ ¹Ñé¹ áÁŒ¨ÐÁÕ¤‹Ò ADI ·ÕèÊÙ§¡Ç‹Ò áμ‹¡çÁÕ¡Òà ÈÖ¡ÉÒ¾ºÇ‹ÒÍÒ¨¡‹ÍãËŒà¡Ô´ÍÒ¡ÒÃᾌ㹼ٌºÃÔâÀ¤ºÒ§¡ÅØ‹Áä´Œ  √ÿªº≈°“√»÷°…“

¼Å¡ÒûÃÐàÁÔ¹¤ÇÒÁàÊÕ觢ͧ¡ÒÃä´ŒÃѺÊÑÁ¼ÑÊÊÕÊѧà¤ÃÒÐˏ ¼ÊÁÍÒËÒ÷Ñé§ËÁ´·Õ辺ã¹ÍÒËÒëÖè§à´ç¡¹Ñ¡àÃÕ¹¹ÔÂÁºÃÔâÀ¤ àÁ×èÍ»ÃÐàÁÔ¹·ÕèÃдѺà©ÅÕè¢ͧ¡ÒúÃÔâÀ¤ ¾ºÇ‹Òà´ç¡¹Ñ¡àÃÕ¹㹠¾×é ¹ ·Õè à ¢μàÁ× Í §¢Í§¡ÃØ § à·¾ÁËÒ¹¤ÃáÅо×é ¹ ·Õè à ¢μª¹º·¢Í§ ¹¤Ã»°Á ä´ŒÃѺÊÑÁ¼ÑÊÊÕàËÅ‹Ò¹Õéã¹ÃдѺ·ÕèμèÓ¡Ç‹Ò¤‹Ò ADI ¢Í§ ÊÕáμ‹ÅЪ¹Ô´ÁÒ¡ «Ö觶×ÍÇ‹ÒäÁ‹ÁÕ¹ÑÂÊÓ¤Ñޢͧ¤ÇÒÁàÊÕè§ ¨Ö§äÁ‹¹‹Ò ¡‹ÍãËŒà¡Ô´¼ÅàÊÕÂμ‹ÍÊØ¢ÀÒ¾¼ÙŒºÃÔâÀ¤ áÁŒÇ‹ÒÃдѺ¢Í§¤ÇÒÁàÊÕ觷Õè »ÃÐàÁԹ䴌¨Ò¡¡ÒÃä´ŒÃѺÊÑÁ¼ÑÊÊÕÊѧà¤ÃÒÐˏ·Ñé§ 7 ª¹Ô´ ·Õ辺㹠ÍÒËÒëÖè§à´ç¡¹ÔÂÁºÃÔâÀ¤¨ÐÁÕ¤‹ÒμèÓ¡Ç‹Ò¤‹Ò ADI áμ‹ÂѧÁÕ¤ÇÒÁ ¨Ó໚¹·ÕèμŒÍ§ÁÕ¡ÒÃཇÒÃÐÇѧ¡ÒÃ㪌ÊÕ¡ÅØ‹ÁÊÕàËÅ×ͧáÅÐÊÕá´§«Öè§à»š¹ ÊÕ ·Õè ¹Ô Â ÁãÊ‹ ã ¹ÍÒËÒÃËÅÒÂÃÒ¡ÒÃÍ‹ Ò §ã¡ÅŒ ªÔ ´ â´Â੾ÒÐ àÍÍÃÔâ¸Ã«Õ¹ áÅЫѹà«çμ àÂçÅâÅǏ àÍç¿«ÕàÍç¿ «Öè§à»š¹ÊÕ·ÕèÁÕ¤‹Ò ADI μèÓ ·ÓãËŒÁÕâÍ¡ÒÊ·Õè¨Ð¡‹ÍãËŒà¡Ô´¤ÇÒÁàÊÕè§㹡ÒÃä´ŒÃѺ ÊÑÁ¼ÑÊ·ÕèÊÙ§à¡Ô¹¤‹Ò ADI ä´Œ¶ŒÒÁÕ¡ÒúÃÔâÀ¤ÍÒËÒ÷ÕèãÊ‹ÊÕàËÅ‹Ò¹Õéã¹ »ÃÔÁÒ³ÁÒ¡ ´Ñ§¨ÐàËç¹Ç‹ÒàÁ×èͤӹdz»ÃÔÁÒ³¡ÒÃä´ŒÃѺÊÑÁ¼ÑÊÊÕ áμ‹ÅЪ¹Ô´à»ÃÕºà·Õº¡Ñº¤‹Ò ADI ¢Í§ÊÕª¹Ô´¹Ñé¹ ¾ºÇ‹Òà´ç¡ ¹Ñ¡àÃÕ¹¹Í¡à¢μà·ÈºÒŹ¤Ã»°Á¨Ðä´ŒÃѺÊÑÁ¼ÑÊÊÕàÍÍÃÔâ¸Ã«Õ¹ã¹ ÃдѺ¤ÇÒÁàÊÕ觷ÕèÊÙ§¡Ç‹ÒÊÕÍ×è¹ â´Â੾ÒÐàÁ×èÍ»ÃÐàÁÔ¹¡ÒÃä´ŒÃѺ ÊÑÁ¼ÑÊÊÕ¹Õé¨Ò¡¡ÒúÃÔâÀ¤äÊŒ¡ÃÍ¡áÅÐÅÙ¡ªÔé¹ ·ÕèÃдѺ¡ÒúÃÔâÀ¤ÊÙ§ (ÃдѺ 97.5 à»ÍÏà«ç¹ä·Å) à¹×èͧ¨Ò¡à»š¹ÊÕ·Õè¹ÔÂÁ㪌ã¹ÍÒËÒà »ÃÐàÀ·äÊŒ¡ÃÍ¡áÅÐÅÙ¡ªÔé¹ ·Õè¼ÅÔμã¹ÃдѺ¤ÃÑÇàÃ×͹áÅÐâç§Ò¹ ¢¹Ò´àÅç¡ äÊŒ¡ÃÍ¡áÅÐÅÙ¡ªÔé¹à»š¹ÍÒËÒ÷Õèà´ç¡¹Ñ¡àÃÕ¹㹾×é¹·Õè¹Õé ¹ÔÂÁºÃÔâÀ¤·Ñé§ã¹»ÃÔÁÒ³áÅФÇÒÁ¶Õè·ÕèÊÙ§ ´Ñ§¹Ñ鹡ÒüÅÔμÍÒËÒà ¼ÊÁÊÕÍ‹ҧäÁ‹àËÁÒÐÊÁ㹤ÃÑÇàÃ×͹ËÃ×ÍÍØμÊÒË¡ÃÃÁ¢¹Ò´àÅç¡ ¨Ö§à»š¹»˜ÞËÒ·ÕèμŒÍ§ÁÕ¡ÒÃá¡Œä¢Í‹ҧà˧´‹Ç¹ â´Â¤ÇÃÁÕ¡ÒÃͺÃÁ ãËŒ¤ÇÒÁÃÙŒ¼ÙŒ¼ÅÔμ㹡ÒÃ㪌ÊÕÊѧà¤ÃÒÐˏ¼ÊÁÍÒËÒÃãËŒàËÁÒÐÊÁ ·Ñ駪¹Ô´ »ÃÔÁÒ³ áÅÐÇÑμ¶Ø»ÃÐʧ¤ã¹¡ÒÃ㪌 °‘μμ‘°√√¡ª√–°“»

§Ò¹ÇÔ ¨Ñ  ¹Õé ä ´Œ ÃÑ º ¡ÒÃÊ¹Ñ º Ê¹Ø ¹ ·Ø ¹ ¨Ò¡¡Í§¤Çº¤Ø Á ÍÒËÒà Êӹѡ§Ò¹¤³Ð¡ÃÃÁ¡ÒÃÍÒËÒÃáÅÐÂÒ

«“√ “√‚¿™π“°“√

R1_Nutrition_p28-37_pro1.indd Sec1:36

6/22/09 11:04:52 PM


àÍ¡ÊÒÃ͌ҧÍÔ§

1. ÊÁÈÃÕ ´ÓçÊÇÑÊ´ÔìÇԷ áÅФ³Ð. ÊÕã¹¢¹Áà´ç¡. ÇÒÃÊÒáÃÁÇÔ·ÂÒÈÒÊμÏ¡ÒÃᾷ 2539; 38(1): 81-6. 2. Ê¡ÒÇÃÑμ¹ ªÑÂÊع·Ã áÅФ³Ð. ¤ÇÒÁàËÁÒÐÊÁ¢Í§ÊÕ·Õè㪌ã¹ÅÙ¡ÍÁ«Ö觨Ó˹‹ÒÂ㹨ѧËÇÑ´¹¤Ã¾¹Á. Êӹѡ§Ò¹ÊÒ¸ÒóÊØ¢ ¨Ñ§ËÇÑ´¹¤Ã¾¹Á, ¹¤Ã¾¹Á, 2538. 3. ¨§¡Å¹Õ ÇÔ·ÂÒÃØ‹§àÃ×ͧÈÃÕ. »ÃÔÁÒ³¡ÒÃ㪌ÊÕã¹¢¹Áà´ç¡·Õè¨Ó˹‹ÒÂã¹ÃŒÒ¹¢Ò¢ͧªÓã¹à¢μ¡Ãا෾ Ï áÅÐÀÒ¤¡ÅÒ§. Êӹѡ§Ò¹¤³Ð¡ÃÃÁ¡ÒÃÍÒËÒÃáÅÐÂÒ, ¹¹·ºØÃÕ, 2539. 4. World Health Organization. Summary of Evaluations Performed by the Joint FAO/WHO Expert Committee on food additive, 1956-1996. FAO/IPCS/WHO Geneva, 1996. 5. Watson DH. Food chemical safety volume 2: Additive. England: Wood head publishing limited, 2002: 173-203. 6. Maga JA, Tu AT. Food additive and Toxicology. New York: Marcel Dekker, Inc, 1995: 179-233. 7. ¾ÃÐÃÒªºÑÞÞÑμÔÍÒËÒà ¾.È. 2522 »ÃСÒÈ¡ÃзÃǧÊÒ¸ÒóÊØ¢ ©ºÑº·Õè 66 (¾.È. 2525) ÃÒª¡Ô¨¨Ò¹ØມÉÒ àÅ‹Á·Õè 99 μ͹·Õè 27. (ŧÇѹ·Õè 25 ¡ØÁÀҾѹ¸ 2525) Êӹѡ§Ò¹¤³Ð¡ÃÃÁ¡ÒÃÍÒËÒÃáÅÐÂÒ ¡ÃзÃǧÊÒ¸ÒóÊØ¢. 8. ¾ÃÐÃÒªºÑÞÞÑμÔÍÒËÒà ¾.È. 2522 »ÃСÒÈ¡ÃзÃǧÊÒ¸ÒóÊØ¢ ©ºÑº·Õè 281 (¾.È. 2547) ÃÒª¡Ô¨¨Ò¹ØມÉÒ àÅ‹Á·Õè 121 μ͹¾ÔàÈÉ 97§. (ŧÇѹ·Õè 6 ¡Ñ¹ÂÒ¹ 2547) Êӹѡ§Ò¹¤³Ð¡ÃÃÁ¡ÒÃÍÒËÒÃáÅÐÂÒ ¡ÃзÃǧÊÒ¸ÒóÊØ¢. 9. Joint FAO/WHO Food Standards Programme: Codex Alimentarius Commission. General Standard for Food Additives: Codex Stan 192-1995. Available from: www.codexalimentarius.net/gsfaonline/index.html [Accessed 2005 May]. 10. Pearson, D. The chemical analysis of foods: 7th edition. Churchill Livingstone, London and New York, 1976. 11. Food and Agriculture Organization of the United Nations. Manuals of food quality control 7, food analysis: general techniques, additives contaminants, and composition. FAO, Rome, 1986: 91-2. 12. World Health Organization. Guidelines for the preparation of working papers on intake of food additives for the Joint FAO/WHO Expert Committee on Food Additives, Geneva, 2001 Available from: www.who.int/entity/ipcs/food/jecfa/en/intake guidelines.pdf. [Accessed 2005 May]. 13. Toledo MC, Guerchon MS, Ragazzi S. Potential weekly intake of artificial food colors by 3-14-year-old children in Brazil. Food Addit Contam. 1992;9(4):291-301. 14. Pratima R, Bhat RV, Sudershan RV, Krishna TP, Naidu N. Exposure assessment to synthetic food colors of selected population in Hyderabad, India. Food Addit Contam. 2004;21(5):415-21.

ªï∑’Ë 43 ©∫—∫∑’Ë 4 μÿ≈“§¡ - ∏—𫓧¡ 2551

R1_Nutrition_p28-37_pro1.indd Sec1:37

37

6/22/09 11:04:52 PM


Nutrition

Review

ÃʪÃÔ¹·Ã ÈÔÃÔàÇÔ¹, ªØμÔÁÒ ÈÔÃÔ¡ØŪÂÒ¹¹·

Melanocortin-4 receptor

‚√§Õâ«π

°—∫

38

«“√ “√‚¿™π“°“√

R1_Nutrition_p38-40_pro1.indd Sec1:38

6/22/09 11:11:45 PM


∫∑§—¥¬àÕ

âä͌ǹà¡Ô´¨Ò¡¤ÇÒÁäÁ‹ÊÁ´ØŢͧ¾Åѧ§Ò¹·Õèä´ŒÃѺ ¨Ò¡¡ÒúÃÔâÀ¤¡Ñº¡ÒÃà¼Ò¼ÅÒÞ¾Åѧ§Ò¹ÀÒÂã¹Ã‹Ò§¡Ò ¾Åѧ§Ò¹Ê‹Ç¹à¡Ô¹¨Ð¶Ù¡ÊÐÊÁã¹ÃÙ»ä¢ÁѹμÒÁà¹×éÍàÂ×èÍ μ‹Ò§æ ·ÓãËŒà¡Ô´âä͌ǹ «Öè§Ê‹§¼Åμ‹Í¡ÒÃà¨çº»†Ç¨ҡ âäàÃ×éÍÃѧμ‹Ò§ æ μÒÁÁÒ ÊÒàËμآͧâä͌ǹà¡Ô´¨Ò¡ ¾Ñ ¹ ¸Ø ¡ ÃÃÁáÅÐÊÔè § áÇ´ÅŒ Í Á ·Ñé § Êͧ»˜ ¨ ¨Ñ  ÁÕ ¤ ÇÒÁÊÑÁ¾Ñ¹¸ã¹ÅѡɳÐÊ‹§àÊÃÔÁ«Ö觡ѹáÅСѹ 㹤¹·ÕèÁÕ ¾Ñ¹¸Ø¡ÃÃÁ¢Í§¡ÒÃà¡Ô´âä͌ǹ ¨Ð͌ǹÁÒ¡ÂÔ觢Ö鹶ŒÒäÁ‹ ÍÍ¡¡ÓÅѧ¡ÒÂáÅкÃÔâÀ¤ÍÒËÒ÷ÕèÁÕ¹éÓμÒÅáÅÐä¢Áѹ «Öè §ãËŒ ¾ ÅÑ § §Ò¹ÊÙ § ¡ÒÃÈÖ ¡ ÉÒã¹μ‹ Ò §»ÃÐà·È¾ºÇ‹ Ò ¡ÒÃà¡Ô ´ ¡ÒáÅÒÂ¾Ñ ¹ ¸Ø ã ¹ÂÕ ¹ Melanocortin-4 receptor (MC4R) ໚¹ÊÒàËμØÊÓ¤Ñޢͧ¡ÒÃà¡Ô´âä ÍŒ Ç ¹ã¹ÇÑ Â à´ç ¡ «Öè § ÂÕ ¹ MC4R ÍÂÙ‹ º ¹â¤ÃâÁâ«Á·Õè 18q22 »ÃСͺ´ŒÇ¡ôÍÐÁÔâ¹ 332 μÑÇ ¾ºÁÒ¡ã¹ ÊÁͧʋǹäÎâ»·ÒÅÒÁÑÊ ÁÕº·ºÒ·ÊÓ¤ÑÞ㹡Åä¡¡Òà ¤Çº¤ØÁÊÁ´ØŢͧÍÒËÒÃáÅоÅѧ§Ò¹ã¹Ã‹Ò§¡Ò ¡Òà ¡ÃÐμØŒ¹¡Ò÷ӧҹ¢Í§ MC4R ´ŒÇ α -Melanocyte stimulating hormone ( α -MSH) ¨ÐÅ´¤ÇÒÁÍÂÒ¡ ÍÒËÒÃËÃ× Í ·ÓãËŒ ÃÙŒ ÊÖ ¡ ÍÔè Á áÅÐà¾Ôè Á ¡ÒÃà¼Ò¼ÅÒÞ ¾Åѧ§Ò¹ã¹Ã‹Ò§¡Ò ¡ÒáÅÒ¾ѹ¸Øã¹ÂÕ¹ MC4R ¨Ð ·ÓãËŒ ¡ Å䡹Õé à ¡Ô ´ ¢Öé ¹ äÁ‹ Ê ÁºÙ à ³ ·ÓãËŒ º ÃÔ â À¤ ÍÒËÒÃÁÒ¡¡Ç‹Ò»¡μÔ ¡ÒÃà¼Ò¼ÅÒÞ¾Åѧ§Ò¹ã¹Ã‹Ò§¡Ò Ŵŧ ¨Ö § ·ÓãËŒ à ¡Ô ´âä͌ Ç ¹áÅÐÁÕ ¡ Òö‹ Ò Â·Í´ã¹ ÅѡɳТͧÂչഋ¹ ´Ñ§¹Ñ鹡ÒÃμÃǨËÒ¤ÇÒÁ¼Ô´»¡μÔ ¢Í§ÂÕ¹ MC4R ¨Ö§ÁÕ¤ÇÒÁÊÓ¤ÑÞà¾×èÍËÒá¹Ç·Ò§ã¹ ¡Òû‡Í§¡Ñ¹áÅÐᡌ䢻˜ÞËÒâä͌ǹ·ÕèÁÕ»ÃÐÊÔ·¸ÔÀÒ¾ ÍÕ¡ÇÔ¸Õ˹Öè§ã¹Í¹Ò¤μ ¤ÓÊÓ¤ÑÞ: âä͌ǹ Melanocortin-4 receptor ¾Ñ¹¸Ø¡ÃÃÁ

ͧ¤¡ÒÃ͹ÒÁÑÂâÅ¡ (WHO) ãËŒ¤Ó¹ÔÂÒÁ¢Í§ÀÒÇйéÓ˹ѡà¡Ô¹ áÅÐÍŒÇ¹Ç‹Ò ¤×Í¡Ò÷ÕèËҧ¡ÒÂÁÕ¡ÒÃÊÐÊÁ¢Í§ä¢ÁѹÁÒ¡¡Ç‹Ò»¡μÔ¨¹ Ê‹§¼ÅàÊÕÂμ‹ÍÊØ¢ÀÒ¾ ·ÓãËŒà¡Ô´¡ÒÃà¨çº»†Ç¨ҡâäàÃ×éÍÃѧμ‹Ò§ æ μÒÁÁÒ àª‹¹ âäàºÒËÇÒ¹ âä¤ÇÒÁ´Ñ¹âÅËÔμÊÙ§ âää¢Áѹ ã¹àÅ×Í´¼Ô´»¡μÔ âäËÑÇã¨áÅÐËÅÍ´àÅ×Í´ âäÁÐàÃ秺ҧª¹Ô´1 âä͌ Ç ¹à¡Ô ´ ¨Ò¡¤ÇÒÁäÁ‹ Ê Á´Ø Å ÃÐËÇ‹ Ò §¾ÅÑ § §Ò¹·Õè ä ´Œ ÃÑ º ¨Ò¡ ÍÒËÒ÷Õè º ÃÔ â À¤¡Ñ º ¡ÒÃà¼Ò¼ÅÒÞ¾ÅÑ § §Ò¹ÀÒÂã¹Ã‹ Ò §¡Ò àÁ×è Í ¾Åѧ§Ò¹·Õèä´ŒÃѺ¨Ò¡ÍÒËÒúÃÔâÀ¤ÁÒ¡¡Ç‹Ò¾Åѧ§Ò¹·Õè¶Ù¡ãªŒä»¡ç¨Ð ·ÓãËŒà¡Ô´¡ÒÃÊÐÊÁ¢Í§ä¢ÁѹμÒÁà¹×éÍàÂ×èÍμ‹Ò§ æ ¹Ò¹ä»¡ç¨Ð·ÓãËŒ à¡Ô´âä͌ǹ2-3 ¤ÇÒÁäÁ‹ÊÁ´ØÅ·Õèà¡Ô´¢Öé¹¹ÕéÁÕÊÒàËμØÁÒ¨Ò¡»˜¨¨Ñ·ҧ ´ŒÒ¹¾Ñ¹¸Ø¡ÃÃÁáÅл˜¨¨Ñ·ҧ´ŒÒ¹ÊÔè§áÇ´ÅŒÍÁ ·Ñé§Êͧ»˜¨¨ÑÂÁÕ¤ÇÒÁ ÊÑ Á ¾Ñ ¹ ¸ μ‹ Í ¡ÒÃà¡Ô ´âä͌ Ç ¹ã¹ÅÑ ¡ ɳÐÊ‹ § àÊÃÔ Á «Öè § ¡Ñ ¹ áÅÐ¡Ñ ¹ (synergistic relationship) ¡Å‹ÒǤ×Íã¹¼ÙŒ·ÕèÁվѹ¸Ø¡ÃÃÁ¢Í§¡ÒÃà¡Ô´ âä͌ Ç ¹¨ÐÂÔè § ÍŒ Ç ¹ÁÒ¡àÁ×è Í ÍÂÙ‹ ã ¹ÊÔè § áÇ´ÅŒ Í Á·Õè à ÊÕè  §μ‹ Í ¡ÒÃà¡Ô ´ âä͌ǹ4-5 »˜¨¨Ñ·ҧ´ŒÒ¹ÊÔè§áÇ´ÅŒÍÁ·Õè·ÓãËŒàÊÕè§μ‹Í¡ÒÃà¡Ô´âä͌ǹ ઋ¹ ÇÔ¶ÕªÕÇÔμẺμÐÇÑ¹μ¡·ÕèºÃÔâÀ¤ÍÒËÒ÷ÕèÁÕ·Ñé§á»‡§ ¹éÓμÒÅ áÅÐ ä¢ÁѹÁÒ¡ ¨Ó¾Ç¡ÍÒËÒèҹ´‹Ç¹μ‹Ò§ æ áÅйéÓÍÑ´ÅÁ ·Óãˌ䴌ÃѺ ¾Åѧ§Ò¹à¡Ô¹¡Ç‹Ò¤ÇÒÁμŒÍ§¡ÒÃã¹áμ‹ÅÐÇѹ ÃÇÁ¶Ö§à¤Ã×èͧÍӹǠ¤ÇÒÁÊдǡ·Ñé§ËÅÒ·Õèä»Å´¡Ô¨¡ÃÃÁ·Ò§¡ÒÂŧáÅÐÁÕ¡ÒÃÍÍ¡ ¡ÓÅѧ¡Ò¹ŒÍ »˜¨¨ÑÂàËÅ‹Ò¹ÕéŌǹ·ÓãËŒà¡Ô´âä͌ǹ䴌1 ʋǹ»˜¨¨Ñ·ҧ´ŒÒ¹¾Ñ¹¸Ø¡ÃÃÁ¹Ñé¹ ¡ÒÃÈÖ¡ÉÒã¹μ‹Ò§»ÃÐà·È¾º Ç‹Ò¡ÒÃà¡Ô´¤ÇÒÁ¼Ô´»¡μԢͧÂÕ¹ã¹Ãкº leptin - melanocortin «Ö觤Ǻ¤ØÁÊÁ´ØŢͧÍÒËÒÃáÅоÅѧ§Ò¹ã¹Ã‹Ò§¡Ò·ÓãËŒà¡Ô´âä͌ǹ ä´Œ ÂÕ¹·Õèà¡ÕèÂÇ¢ŒÍ§ 䴌ᡋ ÂÕ¹ leptin (LEP) ÂÕ¹ leptin receptor (LEPR) ÂÕ¹ pro-opiomelanocortin (POMC) ÂÕ¹ prohormone convertase 1 (PC1) áÅÐ ÂÕ¹ melanocortin-4 receptor (MC4R) ËÒ¡à¡Ô´¡ÒáÅÒ¾ѹ¸Ø (mutation) áÁŒà¾Õ§ÂÕ¹ã´ÂÕ¹ ˹Ö觡ç·Óãˌ͌ǹ䴌 â´Â¡ÒáÅÒ¾ѹ¸Øã¹ÂÕ¹¡ÅØ‹Á´Ñ§¡Å‹ÒǨÐÁÕÍÒ¡Òà áÊ´§·Õè Ê Ó¤Ñ Þ ¤× Í ÍŒ Ç ¹μÑé § áμ‹ ÇÑ Â à´ç ¡ (ÍŒ Ç ¹¡‹ Í ¹ÍÒÂØ 10 »‚ ) ¡ÒÃÈÖ¡ÉÒ·Ò§¾Ñ¹¸Ø¡ÃÃÁ¾ºÇ‹Ò¡ÒáÅÒ¾ѹ¸Øã¹ÂÕ¹ MC4R ໚¹âä ͌ǹ·Õèà¡Ô´¨Ò¡¤ÇÒÁ¼Ô´»¡μԢͧÂÕ¹à¾Õ§ÂÕ¹à´ÕÂÇ·Õ辺ÁÒ¡·ÕèÊØ´ ÁÕ ¤ÇÒÁªØ¡μÑé§áμ‹ÃŒÍÂÅÐ 0.5 㹡ÅØ‹ÁμÑÇÍ‹ҧ·Õè͌ǹ¢³Ð໚¹¼ÙŒãËÞ‹ áÅŒÇ áÅÐÊÙ§¶Ö§ÃŒÍÂÅÐ 6 㹡ÅØ‹ÁμÑÇÍ‹ҧ·Õè͌ǹª¹Ô´ÃعáçμÑé§áμ‹ à´ç¡ (severe childhood obesity)6-8 ÂÕ¹ MC4R ໚¹ÂÕ¹·ÕèÍÂÙ‹º¹â¤ÃâÁâ«Á·Õè 18q22 ÁÕ 1 àÍ硫͹ (exon) «Öè § »ÃСͺ´Œ Ç Â 999 ¹Ô Ç ¤ÅÕ â Íä·´ ¤Çº¤Ø Á ¡Òà Êѧà¤ÃÒÐˏâ»ÃμÕ¹ ÂÕ¹ MC4R «Öè§à»š¹μÑÇÃѺ (receptor) ·ÕèÊÓ¤ÑÞ ã¹Ãкº leptin-melanocortin ÂÕ¹ MC4R »ÃСͺ´ŒÇ¡ô ÍÐÁÔ â ¹ 332 μÑ Ç ¾ºÁÒ¡ã¹ÊÁͧʋ Ç ¹äÎâ»·ÒÅÒÁÑ Ê (hypothalamus) «Öè§à»š¹ºÃÔàdz·Õè¤Çº¤ØÁà¡ÕèÂǡѺÊÁ´ØŢͧÍÒËÒà ªï∑’Ë 43 ©∫—∫∑’Ë 4 μÿ≈“§¡ - ∏—𫓧¡ 2551

R1_Nutrition_p38-40_pro1.indd Sec1:39

39

6/22/09 11:13:22 PM


(hyperinsulinemia) ÁÇÅ ¡ÅŒÒÁà¹×éÍ ÁÇÅä¢Áѹ áÅÐ ¤ÇÒÁ˹Òṋ¹¢Í§¡Ãд١ÊÙ§ ·ÓãËŒ¼ÙŒ·ÕèÁÕÀÒÇоËͧ MC4R (MC4R deficiency) ÁÕ ÍÑμÃÒ¡ÒÃà¨ÃÔÞàμÔºâμÊÙ§¡Ç‹Ò ¤¹»¡μÔ11 ¡ Ò Ã ¡ Å Ò Â ¾Ñ ¹ ¸Ø ã ¹ ÂÕ ¹ MC4R ¹Ñé¹ Ê‹Ç¹ÁÒ¡¨Ð¾º ã¹ÅÑ ¡ ɳÐàÎà·ÍâÃä«â¡μ (heterozygote) ¤× Í ¼Ô ´ »¡μÔà¾Õ§ 1 ÍÑÅÅÕÅ (allele) ´Ñ§¹Ñ鹡ÒáÃÐμØŒ¹¡Ò÷ӧҹ ¢Í§ÂÕ¹ MC4R ·Õèä´Œ¨Ò¡¡Òà ÃÙ»·Õè 1 : Leptin-Melanocortin Pathway Êѧà¤ÃÒÐˏ¢Í§ÍÕ¡ 1 ÍÑÅÅÕŠ͌ҧÍÔ§ : List and Habener. N Engl J Med 2003; 348 (12): 1160-3 ·ÕèÂѧ·Ó§Ò¹ä´Œ¨Ö§à»š¹á¹Ç·Ò§ áÅоÅѧ§Ò¹ã¹Ã‹Ò§¡Ò ¡ÒáÃÐμØŒ¹ MC4R ´ŒÇ α -melanocyte 㹡ÒüÅÔ μ ÂÒà¾×è Í ãªŒ ã ¹¡ÒÃÃÑ ¡ ÉÒ¼ÙŒ ·Õè ÁÕ À ÒÇÐ MC4R stimulating hormone ( α -MSH) ¨Ð·ÓãËŒà¡Ô´¡ÒÃÊѧà¤ÃÒÐˏ deficiency6,12 âÁàÅ¡ØÅ·Õè¨ÐÁÒ¡ÃÐμØŒ¹¡Ò÷ӧҹ¢Í§ MC4R ÎÍÏâÁ¹·Õè·ÓãËŒàÃÒÃÙŒÊÖ¡ÍÔèÁ ¼Å¤×Íà¾ÔèÁ¡ÒÃà¼Ò¼ÅÒÞ¾Åѧ§Ò¹ã¹ ¤×Í MC4R agonist «Öè§àÅÕ¹Ẻ¡Ò÷ӧҹ¢Í§ α -MSH Ëҧ¡ÒÂáÅÐÅ´¡ÒúÃÔâÀ¤ÍÒËÒÃŧ (ÃÙ»·Õè 1)9-10 »˜¨¨ØºÑ¹ MC4R agonist ÍÂÙ‹ã¹¢Ñé¹μ͹¡ÒÃÇԨѠ¨Ð¹ÓÁÒ㪌㹠¡ÒáÅÒ¾ѹ¸Øã¹ÂÕ¹ MC4R ¨Ð·ÓãËŒ¡ÒÃÊѧà¤ÃÒÐˏâ»ÃμÕ¹ ¼ÙŒ·ÕèÁÕÀÒÇÐ MC4R deficiency ã¹ÍÕ¡äÁ‹¡Õ軂¢ŒÒ§Ë¹ŒÒ12 MC4R äÁ‹à¾Õ§¾Í (MC4R deficiency) Ê‹§¼ÅãËŒ¡Åä¡·Õè §Ò¹ÇԨѴŒÒ¹¹Õé໚¹·Õ蹋Òʹã¨à¹×èͧ¨Ò¡Ç‹Ò¡ÒÃÈÖ¡ÉÒ¶Ö§¡Òà ·ÓãËŒàÃÒÃÙŒÊÖ¡ÍÔèÁà¡Ô´¢Öé¹äÁ‹ÊÁºÙó ºÃÔâÀ¤ÍÒËÒÃÁÒ¡¡Ç‹Ò»¡μÔ à»ÅÕè¹á»Å§ (variants) ¢Í§ÂÕ¹ MC4R áÅСÒÃËÒ¤ÇÒÁ ¨Ö § ·ÓãËŒ ÍŒ Ç ¹ä´Œ â´ÂÁÕ ¡ Òö‹ Ò Â·Í´ã¹ÅÑ ¡ ɳТͧÂÕ ¹ à´‹ ¹ ÊÑ Á ¾Ñ ¹ ¸ ¢ ͧ¡ÒÃà»ÅÕè  ¹á»Å§·Õè ¤Œ ¹ ¾º¡Ñ º ¡ÒÃà¡Ô ´âä͌ Ç ¹¹Ñé ¹ (dominant) ÍÒ¡ÒÃáÊ´§·ÕèÊÓ¤ÑÞ ä´Œá¡‹ ¡ÒÃÃѺ»ÃзҹÍÒËÒà ໚¹¡ÒÃËÒá¹Ç·Ò§ã¹¡Òû‡Í§¡Ñ¹áÅÐᡌ䢻˜ÞËÒâä͌ǹ·ÕèÁÕ ÁÒ¡¡Ç‹ Ò »¡μÔ (hyperphagia) ÃÐ´Ñ º ÍÔ ¹ «Ù ÅÔ ¹ã¹àÅ× Í ´ÊÙ § »ÃÐÊÔ·¸ÔÀÒ¾ÍÕ¡ÇÔ¸Õ˹Öè§ã¹Í¹Ò¤μ àÍ¡ÊÒÃ͌ҧÍÔ§

1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 40

ADDIN EN.REFLIST 1. World Health Organization. Obesity and overweight. [cited 2008 Apr 6]; Available from: http://www.who.int/mediacentre/factsheets/fs311/en/index.html Rosenbaum M, Leibel RL, Hirsch J. Obesity. N Engl J Med. 1997;337(6):396-407. Spiegelman BM, Flier JS. Obesity and the regulation of energy balance. Cell. 2001;104(4):531-43. Barsh GS, Farooqi IS, O’Rahilly S. Genetics of body-weight regulation. Nature. 2000;404(6778):644-51. Loos RJ, Bouchard C. Obesity--is it a genetic disorder? J Intern Med. 2003;254(5):401-25. Farooqi IS, O’Rahilly S. Monogenic obesity in humans. Annu Rev Med. 2005;56:443-58. Farooqi IS, O’Rahilly S. New advances in the genetics of early onset obesity. Int J Obes (Lond). 2005;29(10):1149-52. Tao YX. Molecular mechanisms of the neural melanocortin receptor dysfunction in severe early onset obesity. Mol Cell Endocrinol. 2005;239(1-2):1-14. Gantz I, Miwa H, Konda Y, Shimoto Y, Tashiro T, Watson SJ, et al. Molecular cloning, expression, and gene localization of a fourth melanocortin receptor. J Biol Chem. 1993;268(20):15174-9. List JF, Habener JF. Defective melanocortin 4 receptors in hyperphagia and morbid obesity. N Engl J Med. 2003;348(12):1160-3. Farooqi IS, Keogh JM, Yeo GS, Lank EJ, Cheetham T, O’Rahilly S. Clinical spectrum of obesity and mutations in the melanocortin 4 receptor gene. N Engl J Med. 2003;348(12):1085-95. Nargund RP, Strack AM, Fong TM. Melanocortin-4 receptor (MC4R) agonists for the treatment of obesity. J Med Chem. 2006;49(14):4035-43.

«“√ “√‚¿™π“°“√

R1_Nutrition_p38-40_pro1.indd Sec1:40

6/22/09 11:11:47 PM


¢âÕ∫—ߧ—∫  ¡“§¡‚¿™π“°“√·Ààߪ√–‡∑»‰∑¬ „πæ√–√“™Ÿª∂—¡¿å ¡‡¥Á®æ√–‡∑æ√—μπ√“™ ÿ¥“ œ  ¬“¡∫√¡√“™°ÿ¡“√’ ©∫—∫·°â‰¢ æ.». 2551 À¡«¥Àπ÷Ëß ™◊ËÕ·≈–«—μ∂ÿª√– ß§å

¢ŒÍ 1. ÊÁÒ¤Á¹Õéª×èÍ “ÊÁÒ¤ÁâÀª¹Ò¡ÒÃáË‹§»ÃÐà·Èä·Âã¹¾ÃÐÃÒªÙ»¶ÑÁÀÊÁà´ç¨¾ÃÐà·¾ÃÑμ¹ÃÒªÊØ´ÒÏ ÊÂÒÁºÃÁÃÒª¡ØÁÒÃÕ” 㪌ÍÑ¡ÉËÍÇ‹Ò “Ê.À.·.” 㪌ÀÒÉÒÍѧ¡ÄÉ “Nutrition Association of Thailand under the Patronage of Her Royal Highness Princess Maha Chakri Sirindhorn” μÑÇÂ‹Í “NAT” Êӹѡ§Ò¹ªÑèǤÃÒǢͧÊÁÒ¤ÁμÑé§ÍÂÙ‹·Õè ¡ÃÁ͹ÒÁÑ ¡ÃзÃǧÊÒ¸ÒóÊØ¢ ¶¹¹μÔÇÒ¹¹· ÍÓàÀÍàÁ×ͧ ¹¹·ºØÃÕ ¨¹¡Ç‹Ò¨ÐËÒ·Õè¶ÒÇÃä´Œ ¢ŒÍ 2. à¤Ã×èͧËÁÒÂμÃҢͧÊÁÒ¤Á໚¹ÃÙ»Ãǧ¢ŒÒǡѺ»ÅÒ Íѹ໚¹ÊÑÞÅѡɳ¢Í§ã¹¹éÓÁÕ»ÅÒ ã¹¹ÒÁÕ¢ŒÒÇ ÍÂً㹡ÃͺãμŒ¾ÃйÒÁÒÀÔä¸ÂÊÁà´ç¨¾ÃÐà·¾ÃÑμ¹ÃÒªÊØ´ÒÏ ÊÂÒÁºÃÁÃÒª¡ØÁÒÃÕ ¢ŒÍ 3. ÇÑμ¶Ø»ÃÐʧ¤¢Í§ÊÁÒ¤ÁâÀª¹Ò¡ÒÃáË‹§»ÃÐà·Èä·ÂÏ Áմѧ¹Õé • Ê‹§àÊÃÔÁÍÒªÕ¾áÅÐÊÒÁѤ¤Õ¸ÃÃÁã¹ÃÐËÇ‹Ò§ÊÁÒªÔ¡ • ¤Œ¹¤ÇŒÒáÅÐÊ‹§àÊÃÔÁÇÔ·ÂÒ¡Ò÷Õèà¡ÕèÂǡѺÍÒËÒÃáÅÐâÀª¹Ò¡ÒÃãËŒà¨ÃÔÞ¡ŒÒÇ˹ŒÒ • à¼Âá¾Ã‹áÅÐâ¦É³Ò¤ÇÒÁÃÙŒ´ŒÒ¹ÍÒËÒÃáÅÐâÀª¹Ò¡Òà • áÅ¡à»ÅÕ蹤ÇÒÁÃÙŒ • ËÇÁÁ×ÍáÅ¡à»ÅÕ蹤ÇÒÁÃÙŒ¡ÑºÊÁÒ¤Á ͧ¤¡Òà ʶҹÈÖ¡ÉÒ áÅÐʶҺѹÍ×è¹ æ • ºÓà¾çÞ»ÃÐ⪹à¾×èÍâÀª¹Ò¡ÒÃÍѹ´Õ¢Í§»ÃЪҪ¹ • ª‹ÇÂàËÅ×ÍÊÁÒªÔ¡àÁ×èÍÁÕàËμبÓ໚¹ã¹´ŒÒ¹ÊÇÑÊ´Ô¡Òà • äÁ‹à¡ÕèÂǡѺ¡ÒÃàÁ×ͧ À¡«¥ Õß ª√–‡¿∑¢Õß ¡“™‘°

ÊÁÒªÔ¡¢Í§ÊÁÒ¤Áẋ§Í͡䴌໚¹ 3 »ÃÐàÀ· ¢ŒÍ 4. ÊÁÒªÔ¡ÊÒÁÑÞ ä´Œá¡‹ • ¼ÙŒ·ÕèÊÓàÃ稡ÒÃÈÖ¡ÉÒÇÔªÒÍÒËÒÃáÅÐâÀª¹Ò¡ÒÃËÃ×ÍÊÒ¢ÒÍ×è¹ æ ·Õèà¡ÕèÂÇ¢ŒÍ§ • ¼ÙŒ·Õèà¤Â»¯ÔºÑμÔËÃ×Í¡ÓÅѧ»¯ÔºÑμÔ˹ŒÒ·Õèã¹á¢¹§§Ò¹ÍÒËÒÃáÅÐâÀª¹Ò¡ÒÃã¹Ç§¡ÒÃμ‹Ò§ æ ÃÇÁ·Ñ駢ͧÃÑ°ºÒÅáÅÐàÍ¡ª¹ ¢ŒÍ 5. ÊÁÒªÔ¡·ÑèÇä» ä´Œá¡‹ ¼ÙŒÊ¹ã¨ã¹§Ò¹ÍÒËÒÃáÅÐâÀª¹Ò¡ÒÃ

ªï∑’Ë 43 ©∫—∫∑’Ë 4 μÿ≈“§¡ - ∏—𫓧¡ 2551

R1_Nutrition_p41-46_pro1.indd Sec1:41

41

6/22/09 11:17:00 PM


¢ŒÍ 6. ÊÁÒªÔ¡¡ÔμμÔÁÈÑ¡´Ôì 䴌ᡋ • ¼ÙŒÁÕà¡ÕÂÃμÔ·ÕèãËŒ¤ÇÒÁËÇÁÁ×ͪ‹ÇÂàËÅ×ÍÊ‹§àÊÃÔÁ§Ò¹´ŒÒ¹ÍÒËÒÃáÅÐâÀª¹Ò¡Òà • ¼ÙŒ·Ã§à¡ÕÂÃμԤس໚¹¾ÔàÈÉ «Ö觤³Ð¡ÃÃÁ¡ÒÃàËç¹ÊÁ¤ÇÃàªÔÞ໚¹ÊÁÒªÔ¡à¾×èÍ໚¹à¡ÕÂÃμÔá¡‹ÊÁÒ¤Á ¢ŒÍ 7. ·Õè»ÃÖ¡ÉÒáÅзÕè»ÃÖ¡ÉÒ¡ÔμμÔÁÈÑ¡´Ôì 䴌ᡋ ¡. ·Õè»ÃÖ¡ÉÒ ¤×Í ¼ÙŒ·Ã§¤Ø³ÇزԫÖè§ä´ŒÃѺàªÔÞâ´Â¤³Ð¡ÃÃÁ¡ÒÃÊÁÒ¤ÁÏ ¢. ·Õè»ÃÖ¡ÉÒ¡ÔμμÔÁÈÑ¡´Ôì ¤×Í ¼ÙŒ¡‹ÍμÑé§ÊÁÒ¤ÁÏ ËÃ×ÍÍ´Õμ¹Ò¡ÊÁÒ¤ÁÏ «Öè§ä´ŒÃѺàªÔÞâ´Â¤³Ð¡ÃÃÁ¡ÒÃÊÁÒ¤ÁÏ À¡«¥ “¡ °“√ ¡—§√‡ªìπ ¡“™‘°

¢ŒÍ 8. ¼ÙŒ»ÃÐʧ¤¨ÐÊÁѤÃ໚¹ÊÁÒªÔ¡ÊÒÁÑÞãËŒÂ×è¹ãºÊÁѤÃμÒÁẺ¢Í§ÊÁÒ¤Áμ‹ÍàÅ¢Ò¸Ô¡Òà â´ÂÁÕÊÁÒªÔ¡ÃѺÃͧ 1 ¤¹ ¢ŒÍ 9. ¼ÙŒ»ÃÐʧ¤¨ÐÊÁѤÃࢌÒ໚¹ÊÁÒªÔ¡·ÑèÇä» ãËŒÂ×è¹ãºÊÁѤÃμÒÁẺ¢Í§ÊÁÒ¤Áμ‹ÍàÅ¢Ò¸Ô¡Òà â´ÂÁÕÊÁÒªÔ¡ÃѺÃͧ 1 ¤¹ ¢ŒÍ 10. ãËŒàÅ¢Ò¸Ô¡ÒùÓÃÒª×èͼٌÊÁѤÃàʹÍμ‹Í·Õè»ÃЪØÁ¤³Ð¡ÃÃÁ¡ÒÃà¾×è;ԨÒóÒ͹ØÁÑμÔÃѺࢌÒ໚¹ÊÁÒªÔ¡ ¢ŒÍ 11. àÁ×èͤ³Ð¡ÃÃÁ¡ÒÃŧÁμÔÃѺ¼ÙŒÊÁѤÃࢌÒ໚¹ÊÁÒªÔ¡áÅŒÇ ãËŒàÅ¢Ò¸Ô¡ÒÃᨌ§ä»Âѧ¼ÙŒÊÁѤÃ໚¹ÅÒÂÅѡɳÍÑ¡Éà ¾ÃŒÍÁ·Ñé§á¨Œ§ÃÐàºÕº¢Í§ÊÁÒ¤ÁáÅлÃСÒȪ×èͼٌ·Õè໚¹ÊÁÒªÔ¡ãËÁ‹ãËŒ·ÃÒº ¢ŒÍ 12. ÊÁÒªÔ¡ÀÒ¾¨ÐàÃÔèÁ¢Öé¹àÁ×èÍÊÁÒªÔ¡ªÓÃФ‹ÒºÓÃاμÒÁÃÐàºÕº¢Í§ÊÁÒ¤ÁàÃÕºÌÍÂáÅŒÇ ¢ŒÍ 13. ¡ÒâҴ¨Ò¡ÊÁÒªÔ¡ÀÒ¾ Áմѧμ‹Í仹Õé • μÒ • ÅÒÍÍ¡ • ¤³Ð¡ÃÃÁ¡ÒÃàËç¹ÊÁ¤ÇÃãËŒÍÍ¡ • μŒÍ§¤Ó¾Ô¾Ò¡ÉÒãˌ໚¹àËÁ×͹ºØ¤¤ÅäÃŒ¤ÇÒÁÊÒÁÒö À¡«¥ ’Ë §à“∫”√ÿß

¢ŒÍ 14. ¤‹ÒºÓÃاÊÁÒªÔ¡μŒÍ§ªÓÃÐ໚¹ÃÒ»‚ ´Ñ§¹Õé ¡. ÊÁÒªÔ¡ÊÒÁÑÞ»‚ÅÐ 300 ºÒ· ¢. ÊÁÒªÔ¡·ÑèÇä»»‚ÅÐ 400 ºÒ· ÊÁÒªÔ¡·Õè໚¹¹Ñ¡ÈÖ¡ÉÒ»‚ÅÐ 200 ºÒ· ÊÁÒªÔ¡ÇÒÃÊÒû‚ÅÐ 500 ºÒ· ¢ŒÍ 15. ¤‹ÒºÓÃاÃÒ»‚ μŒÍ§ªÓÃÐŋǧ˹ŒÒÍ‹ҧ¹ŒÍ 1 à´×͹¡‹Í¹ËÁ´ÍÒÂØ ¢ŒÍ 16. àÁ×èͪÓÃÐà§Ô¹¤‹ÒºÓÃاμ‹ÍÊÁÒªÔ¡áÅŒÇ äÁ‹ÍÒ¨àÃÕ¡¤×¹ä´Œ

42

«“√ “√‚¿™π“°“√

R1_Nutrition_p41-46_pro1.indd Sec1:42

6/22/09 11:17:00 PM


À¡«¥Àâ“  ‘∑∏‘·≈–Àπâ“∑’Ë¢Õß ¡“™‘°

¢ŒÍ 17. ÊÁÒªÔ¡ÁÕÊÔ·¸Ô»ÃдѺà¢çÁà¤Ã×èͧËÁÒ¢ͧÊÁÒ¤Á ¢ŒÍ 18. ÊÁÒªÔ¡ÁÕÊÔ·¸Ô·Õè¨Ðàʹ͢ŒÍ¤Ô´àËç¹μ‹Ò§æ μ‹Í¤³Ð¡ÃÃÁ¡ÒÃÍӹǡÒÃËÃ×Íμ‹Í·Õè»ÃЪØÁãËÞ‹ ÀÒÂ㹢ͺà¢μÇÑμ¶Ø»ÃÐʧ¤¢Í§ÊÁÒ¤Á ¢ŒÍ 19. ÊÁÒªÔ¡ÁÕÊÔ·¸ÔࢌһÃЪØÁ㹡ÒûÃЪØÁãËÞ‹áÅСÒûÃЪØÁÇÔªÒ¡Òà ¢ŒÍ 20. ÊÁÒªÔ¡ÊÒÁÑÞà·‹Ò¹Ñé¹·ÕèÁÕÊÔ·¸ÔÍÍ¡àÊÕ§·ÕèàÅ×Í¡μÑé§ áÅÐä´ŒÃѺ¡ÒÃàÅ×Í¡μÑé§à»š¹¡ÃÃÁ¡ÒÃÍӹǡÒà 㹡ÒÃŧ¤Ðá¹¹àÊÕ§ãËŒÍÍ¡àÊÕ§ãËŒ¤¹ÅÐ˹Öè§àÊÕ§ ¢ŒÍ 21. ÊÁÒªÔ¡ÁÕÊÔ·¸Ô·Õè¨Ðä´ŒÃѺ»ÃÐ⪹μ‹Ò§æ ·ÕèÊÁÒ¤Á¨ÐÍÓ¹ÇÂãËŒ ·Ñ駹ÕéμŒÍ§ÍÂً㹢ͺà¢μÇÑμ¶Ø»ÃÐʧ¤ áÅÐ໚¹ä»ä´ŒμÒÁÃÐàºÕº¢ŒÍºÑ§¤Ñº¢Í§ÊÁÒªÔ¡ ¢ŒÍ 22. ÊÁÒªÔ¡¼ÙŒã´à»ÅÕ蹪×èÍ Ê¡ØÅ ·ÕèÍÂÙ‹ ËÃ×ÍÊӹѡ§Ò¹μŒÍ§á¨Œ§ãËŒàÅ¢Ò¸Ô¡Ò÷ÃÒº À¡«¥À° °“√¥”‡π‘πß“π¢Õß ¡“§¡

¢ŒÍ 23. ¤³Ð¡ÃÃÁ¡ÒÃÍӹǡÒâͧÊÁÒ¤ÁÍѹ»ÃСͺ´ŒÇ ÊÁÒªÔ¡ÊÒÁÑÞ 21 ¤¹ â´Â¡Ó˹´μÓá˹‹§´Ñ§¹Õé • ¹Ò¡ 1 ¤¹ • ÍØ»¹Ò¡ 1 ¤¹ • àÅ¢Ò¸Ô¡Òà 1 ¤¹ • àËÃÑÞÞÔ¡ 1 ¤¹ • ¹Ò·ÐàºÕ¹ 1 ¤¹ • »¯Ô¤Á 1 ¤¹ • ¼ÙŒÃѺ¼Ô´ªÍºÇÔªÒ¡Òà 1 ¤¹ • ¼ÙŒá·¹ÀÒ¤·Õè໚¹¡ÃÃÁ¡ÒÃâ´ÂμÓá˹‹§ 3 ¤¹ • ¡ÃÃÁ¡ÒáÅÒ§ 11 ¤¹ ¢ŒÍ 24. ãËŒÁÕ¡ÒÃàÅ×Í¡μÑ駡ÃÃÁ¡ÒÃÍӹǡÒà 11 ¤¹ ¨Ò¡ÊÁÒªÔ¡ÊÒÁÑ޴ѧ¹Õé ãËŒÁÕ¡ÒûÃСÒÈÃѺÊÁѤÃÊÁÒªÔ¡ÊÒÁÑÞ ¨Ó¹Ç¹Í‹ҧ¹ŒÍ 15 ¤¹ àÁ×èÍÊÔé¹ÊØ´ª‹Ç§àÇÅÒ·Õè»ÃСÒÈÃѺÊÁѤÃËÒ¡Áըӹǹ¼ÙŒÊÁѤÃäÁ‹¤Ãº ãËŒ¤³Ð¡ÃÃÁ¡Òà ÊÃÃËҨӹǹ 5 ¤¹ «Öè§à»š¹¼ÙŒ·Õèä´ŒÃѺ¡ÒÃá싧μÑ駷ӡÒÃÊÃÃËÒ¨Ò¡ÊÁÒªÔ¡ÊÒÁÑÞà¾ÔèÁàμÔÁ¨¹¤ÃºμÒÁ¨Ó¹Ç¹ áÅШѴʋ§ÃÒ¹ÒÁä»ãËŒÊÁÒªÔ¡·Ø¡¤¹Å§¤Ðá¹¹àÅ×Í¡μÑé§ ¼ÙŒ·Õèä´ŒÃѺ¡ÒÃàÅ×Í¡μÑé§ãËŒ¶×ͤÐá¹¹àÊÕ§¨Ò¡ÁÒ¡ä» ËÒ¹ŒÍÂμÒÁÅӴѺ ¶ŒÒ¤Ðá¹¹àÊÕ§෋ҡѹãËŒ¶×Í¡ÒèѺ©Åҡ໚¹¡ÒÃμÑ´ÊÔ¹ ¢ŒÍ 25. ¹Ò¡â´Â¤ÇÒÁàË繪ͺ¢Í§¡ÃÃÁ¡ÒÃÍӹǡÒà ¾Ô¨ÒóÒàÅ×Í¡ÊÁÒªÔ¡ÊÒÁÑÞÍÕ¡ 7 ¤¹ áÅмٌ᷹ÀÒ¤ 3 ¤¹ à¾×èÍá싧μÑé§à»š¹¡ÃÃÁ¡ÒÃãËŒ¤Ãº 21 ¤¹ 㹨ӹǹ¡ÃÃÁ¡Ò÷Ñé§ËÁ´ 21 ¤¹¹Õé 1 ã¹ 3 ¨ÐμŒÍ§äÁ‹à»š¹ ¡ÃÃÁ¡ÒÃ㹤³Ð¡ÃÃÁ¡ÒÃÍӹǡÒ÷Õèà¾Ôè§ÊÔé¹ÊØ´ÇÒÃÐŧ ¢ŒÍ 26. ¤³Ð¡ÃÃÁ¡ÒôÓçμÓá˹‹§ã¹ÇÒÃÐ 2 »‚ ¡ÃÃÁ¡Ò÷Õ辌¹μÓá˹‹§áÅŒÇ ÍҨ䴌ÃѺàÅ×Í¡μÑé§à»š¹¡ÃÃÁ¡ÒÃã¹ÇÒÃÐ μ‹Íä»ä´ŒÍÕ¡ áμ‹äÁ‹à¡Ô¹ 2 ÇÒÃÐ μÔ´μ‹Í¡Ñ¹

ªï∑’Ë 43 ©∫—∫∑’Ë 4 μÿ≈“§¡ - ∏—𫓧¡ 2551

R1_Nutrition_p41-46_pro1.indd Sec1:43

43

6/22/09 11:17:00 PM


¢ŒÍ 27. ÊÓËÃѺ¼ÙŒ·Õèà¤Â´ÓçμÓá˹‹§¹Ò¡ÊÁÒ¤ÁÏ ¤ÃºÊͧÇÒÃÐáÅŒÇ ¨Ðä´ŒÃѺá싧μÑé§à»š¹·Õè»ÃÖ¡ÉÒ¡ÔμμÔÁÈÑ¡´Ôì áÅÐäÁ‹ÊÒÁÒöÊÁѤÃÃѺàÅ×Í¡μÑé§à»š¹¡ÃÃÁ¡ÒÃä´ŒÍÕ¡ ¢ŒÍ 28. ¼ÙŒ·ÕèࢌҴÓçμÓá˹‹§·ÕèNjҧ‹ÍÁÍÂÙ‹ã¹μÓá˹‹§ä´Œà¾Õ§ÇÒÃТͧ¼ÙŒ·Õèμ¹á·¹à·‹Ò¹Ñé¹ ¢ŒÍ 29. ¤³Ð¡ÃÃÁ¡ÒÃÁÕ˹ŒÒ·ÕèºÃÔËÒáԨ¡ÒÃãˌ໚¹ä»μÒÁÃÐàºÕº¢Í§ÊÁÒ¤ÁáÅÐÁμԢͧ·Õè»ÃЪØÁãËÞ‹¡Ó˹´¡Òà »ÃЪØÁãËÞ‹ÊÒÁÑÞ μÑé§Í¹Ø¡ÃÃÁ¡ÒÃáÅÐá싧μÑ駷Õè»ÃÖ¡ÉÒ¡ÃÃÁ¡Òà μÅÍ´¨¹ÊÑ觺ÃèØáÅжʹ¶Í¹à¨ŒÒ˹ŒÒ·Õè»ÃÐ¨Ó ¢Í§ÊÁÒ¤Á ¢ŒÍ 30. ¡ÃÃÁ¡ÒÃÍӹǡÒËÍÁ¢Ò´¨Ò¡μÓá˹‹§â´ÂàËμØã´àËμØ˹Öè§ ´Ñ§μ‹Í仹Õé • μÒ • ÍÍ¡μÒÁÇÒÃÐ • ¢Ò´¨Ò¡¤ÇÒÁ໚¹ÊÁÒªÔ¡ÀÒ¾ • ÅÒÍÍ¡ • ·Õè»ÃЪØÁãËÞ‹ÁÕÁμÔãËŒÍÍ¡â´Â¤Ðá¹¹àÊÕ§ 2 ã¹ 3 ¢Í§¨Ó¹Ç¹ÊÁÒªÔ¡·ÕèÁÒ»ÃЪØÁ㹡óշÕè¡ÃÃÁ¡Òà ÍӹǡÒùÑé¹ ´Óà¹Ô¹¡ÒÃà¡Ô´à»š¹¼ÅàÊÕÂËÒÂá¡‹ÊÁÒ¤Á ËÃ×Í´Óà¹Ô¹§Ò¹¼Ô´¹âºÒ áÅÐÇÑμ¶Ø»ÃÐʧ¤¢Í§ÊÁÒ¤Á ¢ŒÍ 31. ¶ŒÒ¡ÃÃÁ¡ÒÃμÓá˹‹§Ë¹Öè§μÓá˹‹§ã´Ç‹Ò§Å§à¾ÃÒÐàËμØÍ×è¹ ¹Í¡¨Ò¡ÍÍ¡μÒÁÇÒÃÐ ãËŒ¤³Ð¡ÃÃÁ¡ÒôÓà¹Ô¹¡Òôѧμ‹Í仹Õé • ¶ŒÒμÓá˹‹§·ÕèNjҧ໚¹¹Ò¡ ãËŒàÅ×è͹ÍØ»¹Ò¡¢Öé¹ä»á·¹ áÅÐàÅ×Í¡μÑ駡ÃÃÁ¡ÒÃÍ×è¹à¢ŒÒ໚¹ÍØ»¹Ò¡ áŌǨ֧àÅ×Í¡μÑé§ÊÁÒªÔ¡ÊÒÁÑÞã¹Íѹ´Ñºμ‹Í仹Õé ࢌÒ໚¹¡ÃÃÁ¡ÒÃá·¹¡ÃÃÁ¡Òüٌ¹Ñé¹ • μÓá˹‹§¹Í¡¹Ñé¹ãËŒ¹Ò¡໚¹¼ÙŒ¾Ô¨ÒóÒàÅ×Í¡¨Ò¡¡ÃÃÁ¡ÒÃÍ×è¹à¢ŒÒ´ÓçμÓá˹‹§á·¹áÅŒÇàÅ×Í¡μÑé§ÊÁÒªÔ¡ÊÒÁÑÞ ·Õèä´ŒÃѺàÅ×Í¡μÑé§ã¹Íѹ´Ñºμ‹Íä»à¢ŒÒ໚¹¡ÃÃÁ¡ÒÃá·¹μÒÁÅӴѺ • ¼ÙŒà¢ŒÒ´ÓçμÓá˹‹§á·¹μÓá˹‹§·ÕèÇ‹Ò§ ‹ÍÁÍÂÙ‹ã¹μÓá˹‹§ä´Œà¾Õ§ÇÒÃТͧ¼ÙŒ·Õèμ¹á·¹à·‹Ò¹Ñé¹ ¢ŒÍ 32. ¡ÃÃÁ¡ÒÃáμ‹ÅÐμÓá˹‹§ ÁÕ˹ŒÒ·Õè´Ñ§μ‹Í仹Õé ¹Ò¡ÊÁÒ¤Á ÁÕ˹ŒÒ·Õè • ໚¹ËÑÇ˹ŒÒÃѺ¼Ô´ªÍºã¹¡ÒúÃÔËÒáԨ¡ÒâͧÊÁÒ¤Á ÍØ»¹Ò¡ ÁÕ˹ŒÒ·Õè • ·Ó¡ÒÃá·¹¹Ò¡àÁ×è͹Ò¡äÁ‹ÍÂÙ‹ËÃ×ÍäÁ‹ÊÒÁÒö»¯ÔºÑμԧҹ䴌ËÃ×Í¢ÍÌͧãËŒÍØ»¹Ò¡·Ó§Ò¹á·¹ àÅ¢Ò¸Ô¡Òà ÁÕ˹ŒÒ·Õè ÊÒúÃó·ÑèÇ仡ѺÁÕ˹ŒÒ·Õè੾ÒÐ ´Ñ§¹Õé • ໚¹¼ÙŒμÔ´μ‹Í¡ÑºÊÁÒªÔ¡áÅÐͧ¤¡Ã·ÑèÇä» • ¹Ñ´»ÃЪØÁ¡ÃÃÁ¡Òà »ÃЪØÁÇÔªÒ¡Òà áÅлÃЪØÁãËÞ‹μÒÁ¤ÓÅÑ觹Ò¡ ËÃ×ÍμÒÁÁμÔ·Õè»ÃЪØÁ¤³Ð¡ÃÃÁ¡ÒÃáÅŒÇáμ‹¡Ã³Õ • ·ÓÃÒ§ҹ¡ÒûÃЪØÁáÅÐà¡çºÃÑ¡ÉÒänj໚¹ËÅÑ¡°Ò¹ • ·ÓÃÒ§ҹ»ÃШӻ‚

44

«“√ “√‚¿™π“°“√

R1_Nutrition_p41-46_pro1.indd Sec1:44

6/22/09 11:17:00 PM


àËÃÑÞÞÔ¡ÁÕ˹ŒÒ·Õè • ÃѺ¨‹Ò ÃÑ¡ÉÒà§Ô¹¢Í§ÊÁÒ¤Á • ·ÓºÑÞªÕ§ºà´×͹ ºÑÞªÕ§º´ØÅ áÅЧº»ÃÐÁÒ³»ÃШӻ‚ àʹͤ³Ð¡ÃÃÁ¡ÒÃÍӹǡÒäǺ¤ØÁ ¡ÒÃÃѺ¨‹ÒÂμÒÁ§º»ÃÐÁÒ³¡ÒÃà§Ô¹ • àʹͺÑÞªÕ§º´ØŢͧÊÁÒ¤ÁáÅЧº»ÃÐÁÒ³»ÃШӻ‚¢Í§ÊÁÒ¤Áμ‹Í·Õè»ÃЪØÁãËÞ‹ÊÒÁÑÞ»ÃШӻ‚ »¯Ô¤Á ÁÕ˹ŒÒ·Õè • ´ÙáÅʶҹ·ÕèáÅÐÍÊѧËÒÃÔÁ·ÃѾ¢Í§ÊÁÒ¤Á μŒÍ¹ÃѺáÅÐãËŒ¤ÇÒÁÊдǡᡋÊÁÒªÔ¡ ¹Ò·ÐàºÕ¹ ÁÕ˹ŒÒ·Õè • ËÇÁºÃÔËÒçҹ¢Í§ÊÁÒ¤Á ãËŒ¤ÇÒÁàËç¹áÅТŒÍá¹Ð¹Óá¡‹¤³Ð¡ÃÃÁ¡ÒÃ㹡ÒúÃÔËÒçҹËÃ×ͪ‹ÇÂ㹡Òà »¯ÔºÑμÔ˹ŒÒ·ÕèÍ‹ҧã´Í‹ҧ˹Öè§μÒÁ·Õèä´ŒÃѺÁͺËÁÒ¨ҡ¤³Ð¡ÃÃÁ¡Òà ¼ÙŒÃѺ¼Ô´ªÍºÇÔªÒ¡Òà ÁÕ˹ŒÒ·Õè • ºÃÔËÒçҹ´ŒÒ¹ÇÔªÒ¡ÒâͧÊÁÒ¤Á ¡ÃÃÁ¡ÒÃÍ×è¹æ • ໚¹¼ÙŒÃ‹ÇÁºÃÔËÒçҹ¢Í§ÊÁÒ¤ÁãËŒ¤ÇÒÁàËç¹áÅТŒÍá¹Ð¹Ó㹡Òû¯ÔºÑμÔ˹ŒÒ·ÕèÍ‹ҧã´Í‹ҧ˹Öè§μÒÁ·Õèä´Œ ÃѺÁͺËÁÒ¨ҡ¤³Ð¡ÃÃÁ¡Òà À¡«¥‡®Á¥ °“√ª√–™ÿ¡§≥–°√√¡°“√Õ”π«¬°“√

¢ŒÍ 33. ãËŒÁÕ¡ÒûÃЪØÁ¤³Ð¡ÃÃÁ¡ÒÃÍӹǡÒÃÍ‹ҧ¹ŒÍ 2 à´×͹μ‹Í¤ÃÑé§ ¢ŒÍ 34. ¡ÃÃÁ¡ÒÃμŒÍ§ÁÒ»ÃЪØÁÍ‹ҧ¹ŒÍ¤ÃÖè§Ë¹Ö觨֧¨Ð¤ÃºÍ§¤»ÃЪØÁ À¡«¥·ª¥ °“√ª√–™ÿ¡ ¡“™‘°

¢ŒÍ 35. ãËŒÁÕ¡ÒûÃЪØÁãËÞ‹ÊÒÁÑÞ»ÃШӻ‚Í‹ҧ¹ŒÍ»‚ÅФÃÑé§à¾×èÍá싧μÑ駼ٌμÃǨºÑÞªÕ͹ØÁÑμÔÃÒ§ҹ§º»ÃÐÁÒ³ áÅЧº´ØÅ»ÃШӻ‚ ·Ñ駹ÕéμŒÍ§á¨Œ§ãËŒÊÁÒªÔ¡·ÃÒº¡Ó˹´Å‹Ç§Ë¹ŒÒäÁ‹¹ŒÍÂ¡Ç‹Ò 15 Çѹ ¢ŒÍ 36. ¡ÒûÃЪØÁãËÞ‹ÊÒÁÑÞ»ÃШӻ‚ μŒÍ§ÁÕÊÁÒªÔ¡ÊÒÁÑÞÁÒ»ÃЪØÁäÁ‹¹ŒÍÂ¡Ç‹Ò 1 㹢ͧ¨Ó¹Ç¹ÊÁÒªÔ¡ÊÒÁÑÞ ·Õè»ÃÒ¡¯ã¹·ÐàºÕ¹ ËÃ×ÍäÁ‹¹ŒÍÂ¡Ç‹Ò 30 ¤¹ ¨Ö§¨Ð໚¹Í§¤»ÃЪØÁä´Œ ÁμԢͧ·Õè»ÃЪØÁãËދ㪌¤Ðá¹¹àÊÕ§ ¢ŒÒ§ÁÒ¡ ¶ŒÒ¤Ðá¹¹àÊÕ§෋ҡѹ »ÃиҹÁÕÊÔ·¸Ôŧ¤Ðá¹¹àÊÕ§ªÕé¢Ò´ ¢ŒÍ 37. 㹡óըÓ໚¹ ¤³Ð¡ÃÃÁ¡ÒÃÍӹǡÒÃäÁ‹¹ŒÍÂÇ‹Ò 1 ã¹ 3 ËÃ×ÍÊÁÒªÔ¡ÊÒÁÑިӹǹäÁ‹¹ŒÍÂ¡Ç‹Ò 30 ¤¹ ÍÒ¨¢ÍãËŒàÃÕ¡¡ÒûÃЪØÁãËÞ‹ÇÔÊÒÁÑÞ â´ÂÂ×蹤ÇÒÁ¨Ó¹§à»š¹ÅÒÂÅѡɳÍÑ¡ÉÃμ‹ÍàÅ¢Ò¸Ô¡ÒÃãËŒ·ÃҺŋǧ˹ŒÒ äÁ‹¹ŒÍÂ¡Ç‹Ò 15 Çѹ â´Â¡ÒûÃЪØÁãËÞ‹ÇÔÊÒÁÑÞ μŒÍ§ÁÕÊÁÒªÔ¡ÊÒÁÑÞÁÒ»ÃЪØÁäÁ‹¹ŒÍÂ¡Ç‹Ò 1 ã¹ 2 ¢Í§ ÊÁÒªÔ¡ÊÒÁÑÞ·Ñé§ËÁ´ ¨Ö§à»š¹Í§¤»ÃЪØÁä´Œ ¡ÒÃŧÁμԢͧ·Õè»ÃЪØÁÇÔÊÒÁÑÞãËŒ¶×Í»¯ÔºÑμÔઋ¹à´ÕÂǡѺ¡ÒÃŧ ÁμԢͧ·Õè»ÃЪØÁãËÞ‹ÊÒÁÑÞ ¢ŒÍ 38. 㹡ÒûÃЪØÁãËÞ‹·Ñé§ÊÒÁÑÞáÅÐÇÔÊÒÁÑÞ ãËŒ¹Ò¡໚¹»Ãиҹ㹷Õè»ÃЪØÁ ¶ŒÒ¹Ò¡ÊÁÒ¤ÁÏ äÁ‹ÍÂÙ‹ ãËŒÍØ»¹Ò¡·Ó˹ŒÒ·Õèá·¹ á싶ŒÒ¹Ò¡ÊÁÒ¤ÁÏ áÅÐÍØ»¹Ò¡äÁ‹ÍÂÙ‹ ãËŒ·Õè»ÃЪØÁàÅ×Í¡»Ãиҹ¡Ñ¹àͧ੾ÒÐ ¡ÒûÃЪØÁãËÞ‹¤ÃÒǹÑé¹

ªï∑’Ë 43 ©∫—∫∑’Ë 4 μÿ≈“§¡ - ∏—𫓧¡ 2551

R1_Nutrition_p41-46_pro1.indd Sec1:45

45

6/22/09 11:17:00 PM


¢ŒÍ 39. ãËŒÁÕ¡ÒûÃЪØÁÇÔªÒ¡ÒÃ໚¹¤ÃÑ駤ÃÒÇμÒÁ¡Ó˹´·Õ褳СÃÃÁ¡ÒÃÍӹǡÒÃàËç¹ÊÁ¤Çà ¢ŒÍ 40. 㹡ÒûÃЪØÁÇÔªÒ¡ÒÃãËŒ¤³Ð¡ÃÃÁ¡ÒÃàÅ×Í¡»ÃиҹμÒÁáμ‹àËç¹ÊÁ¤Çà À¡«¥‡°â“ °“√‡ß‘π¢Õß ¡“§¡

à§Ô¹¢Í§ÊÁÒ¤ÁμŒÍ§¹Ó份ҡ¸¹Ò¤ÒÃà¾×èÍËÒ´Í¡àºÕé àËÃÑÞÞÔ¡¨ÐÃÑ¡ÉÒà§Ô¹Ê´äÇŒäÁ‹à¡Ô¹ 10,000.- ºÒ· ËÃ×Íâ´Â¤ÇÒÁàË繪ͺ¢Í§¡ÃÃÁ¡ÒÃÍӹǡÒà ¡ÒÃÊÑ觨‹ÒÂà§Ô¹¨Ò¡¸¹Ò¤Òà μŒÍ§ÁÕÅÒÂÁ×ͪ×èÍ 2 ¤¹ ¤×Í ¹Ò¡ËÃ×ÍÍØ»¹Ò¡ áÅÐàËÃÑÞÞÔ¡ ãËŒ¤³Ð¡ÃÃÁ¡ÒÃÁÕÍÓ¹Ò¨ÇÒ§ÃÐàºÕºà¡ÕèÂǡѺ¡Òè‹ÒÂÃÑ¡ÉÒà§Ô¹ • ÍÓ¹Ò¨¡Òè‹ÒÂà§Ô¹¢Í§¹Ò¡ÊÁÒ¤Á 50,000.- ºÒ· • ÍÓ¹Ò¨¡Òè‹ÒÂà§Ô¹¢Í§àËÃÑÞÞÔ¡ 10,000.- ºÒ· ¢ŒÍ 45. ãËŒ¤³Ð¡ÃÃÁ¡ÒèѴ·Ó§º»ÃÐÁÒ³»ÃШӻ‚ §º´ØÅ»ÃШӻ‚ áÊ´§ÃÒÂÃѺÃÒ¨‹ÒÂμ‹Í·Õè»ÃЪØÁãËŒáÅŒÇàÊÃç¨ áÅÐ Ê‹§ãËŒÊÁÒªÔ¡·ÃÒº¡‹Í¹Çѹ»ÃЪØÁãËÞ‹äÁ‹¹ŒÍÂ¡Ç‹Ò 15 Çѹ ¢ŒÍ 46. ¤³Ð¡ÃÃÁ¡ÒÃμŒÍ§¨‹ÒÂà§Ô¹ÀÒÂ㹧º»ÃÐÁÒ³·Õèä´ŒÃѺ͹ØÁÑμÔ àÇŒ¹áμ‹¡Ã³Õ·Õè¨Ó໚¹ãËŒ¹Ò¡ÁÕÍÓ¹Ò¨ÊÑ觨‹Ò ¹Í¡à˹×ͨҡ§º»ÃÐÁÒ³¨‹ÒÂä´ŒäÁ‹à¡Ô¹ÃŒÍÂÅÐ 10 ¢Í§§º»ÃÐÁÒ³»ÃШӻ‚ ¢ŒÍ 47. ¤³Ð¡ÃÃÁ¡ÒÃμŒÍ§¨Ñ´ãËŒÁÕºÑުմѧμ‹Í仹ÕéãËŒ¶Ù¡μŒÍ§ ¤×Í • ºÑÞªÕÃÒÂÃѺÃÒ¨‹Ò¢ͧÊÁÒ¤Á • ºÑÞªÕ·ÃѾÊÔ¹áÅÐ˹ÕéÊÔ¹¢Í§ÊÁÒ¤Á ¢ŒÍ ¢ŒÍ ¢ŒÍ ¢ŒÍ

41. 42. 43. 44.

À¡«¥ ‘∫ °“√‡≈‘° ¡“§¡·≈–°“√™”√–∫—≠™’

¢ŒÍ 48. ¡ÒÃàÅÔ¡ÊÁÒ¤Á¨Ð¡ÃзÓä´Œâ´Â¤Ðá¹¹àÊÕ§ 3 ã¹ 4 ¢Í§ÊÁÒªÔ¡·Ñé§ËÁ´ ¢ŒÍ 49. ãËŒ·Õè»ÃЪØÁãËދŧÁμÔá싧μÑ駼ٌªÓÃкÑÞªÕ ¡ÒêÓÃкÑÞªÕ¹Ñé¹ãˌ໚¹ä»μÒÁ¡®ËÁÒ ¢ŒÍ 50. ·ÃѾÊÔ¹·ÕèàËÅ×ͨҡ¡ÒêÓÃкÑÞªÕÁÕà·‹Òã´ ãˌ໚¹¢Í§¹ÔμԺؤ¤Å·ÕèÁÕÇÑμ¶Ø»ÃÐʧ¤Í‹ҧà´ÕÂǡѹ ËÃ×Í¡ÒáØÈÅÍ×è¹æ μÒÁ·Õè»ÃЪØÁãËÞ‹àËç¹ÊÁ¤ÇÃ

46

«“√ “√‚¿™π“°“√

R1_Nutrition_p41-46_pro1.indd Sec1:46

6/22/09 11:17:00 PM


Nutrition

 ¡“§¡‚¿™π“°“√·Ààߪ√–‡∑»‰∑¬ „πæ√–√“™Ÿª∂—¡¿å ¡‡¥Á®æ√–‡∑æ√—μπ√“™ ÿ¥“ œ  ¬“¡∫√¡√“™°ÿ¡“√’ ¢Õ‡™‘≠™«π√à«¡ª√–°«¥ÕÕ°·∫∫μ√“ —≠≈—°…≥å

ç¡Ÿ≈π‘∏‘æ—≤π“‚¿™π“°“√ (Nutrition Development Foundation)é ¢ÍàªÔުǹÊÁÒªÔ¡áÅмٌʹ㨷ء·‹Ò¹ ËÇÁ»ÃСǴÍ͡ẺμÃÒÊÑÞÅѡɳ¢Í§ “ÁÙŹԸԾѲ¹ÒâÀª¹Ò¡Òà (Nutrition Development Foundation)” ´ŒÇ¾ѹ¸¡Ô¨¢Í§ÊÁÒ¤ÁâÀª¹Ò¡ÒÃáË‹§»ÃÐà·Èä·Â ã¹¾ÃÐÃÒªÙ»¶ÑÁÀÊÁà´ç¨¾ÃÐà·¾ÃÑμ¹ÃÒªÊØ´ÒÏ ÊÂÒÁºÃÁÃÒª¡ØÁÒÃÕ ·ÕèÁØ‹§ÁÑè¹ã¹¡ÒÃÊ‹§àÊÃÔÁáÅÐà¼Âá¾Ã‹¤ÇÒÁÃÙŒ´ŒÒ¹ÍÒËÒÃáÅÐâÀª¹Ò¡ÒÃÊÙ‹Êѧ¤ÁáÅкÓà¾çÞ»ÃÐ⪹à¾×èÍ âÀª¹Ò¡Ò÷Õè´Õ¢Í§»ÃЪҪ¹ ¤³Ð¡ÃÃÁ¡ÒÃÍӹǡÒÃÊÁÒ¤ÁÏ ¨Ö§ÁÕÁμÔãËŒ¡‹ÍμÑé§ “ÁÙŹԸԾѲ¹ÒâÀª¹Ò¡ÒÔ â´ÂÁÕÇÑμ¶Ø»ÃÐʧ¤ ´Ñ§¹Õé 1. ´Óà¹Ô¹§Ò¹à¾×èÍàÊÃÔÁÊÌҧ¤ÇÒÁÃÙŒ´ŒÒ¹âÀª¹Ò¡ÒëÖè§à»š¹¨Ø´àª×èÍÁ⧴ŒÒ¹ÍÒËÒÃáÅÐÊØ¢ÀÒ¾ 2. Ê‹§àÊÃÔÁáÅÐʹѺʹع¡ÒùӤÇÒÁÃÙŒ´ŒÒ¹ÍÒËÒà âÀª¹Ò¡Òà áÅÐÊØ¢ÀҾ任ÃÐÂØ¡μãªŒã¹ªÕÇÔμ »ÃШÓÇѹà¾×è͹Óä»ÊÙ‹ÀÒÇÐ âÀª¹Ò¡Ò÷Õè´ÕáÅÐÂÑè§Â×¹ 3. àÊÃÔÁÊÌҧ¢Õ´¤ÇÒÁÊÒÁÒö¢Í§ÊÁÒªÔ¡áÅлÃЪҪ¹ã¹¡ÒùӤÇÒÁÃÙŒä»ÊÙ‹¡Òû¯ÔºÑμÔà¾×èÍÊØ¢ÀÒÇзÕè´Õ 㹡ÒùÕéÊÁÒ¤ÁÏ »ÃÐʧ¤ãËŒÁÕμÃÒÊÑÞÅѡɳà¾×èÍ㪌㹡ÒûÃЪÒÊÑÁ¾Ñ¹¸áÅÐáÊ´§¶Ö§ÍÑμÅѡɳ¢Í§ÁÙŹԸԼ‹Ò¹Ê×èÍμ‹Ò§æ â´Â ÁÕ¤ÇÒÁÊÍ´¤ÅŒÍ§¡ÑºÇÑμ¶Ø»ÃÐʧ¤¢Í§ÁÙŹԸÔÏ ´Ñ§¹Ñ鹨֧䴌¨Ñ´ãËŒÁÕ¡ÒûÃСǴÍ͡ẺμÃÒÊÑÞÅѡɳ¢Öé¹ • ÃÒÂÅÐàÍÕ´¡ÒÃÊ‹§¼Å§Ò¹Í͡ẺμÃÒÊÑÞÅѡɳ • Ê‹§¼Å§Ò¹·ÕèÍ͡Ẻ´ŒÇÂâ»Ãá¡ÃÁ¤ÍÁ¾ÔÇàμÍÏã¹ÃٻẺÊÕáÅТÒÇ-´Ó • ¼Å§Ò¹·ÕèÊ‹§»ÃСǴÍ͡Ẻ´ŒÇÂμ¹àͧ äÁ‹à¤ÂÊ‹§»ÃСǴ·Õèã´ÁÒ¡‹Í¹ áÅÐäÁ‹ÅÍ¡àÅÕ¹ẺËÃ×Í´Ñ´á»Å§¨Ò¡§Ò¹¢Í§¼ÙŒÍ×è¹ • ÁÕ¤ÓÇ‹Ò “ÁÙŹԸԾѲ¹ÒâÀª¹Ò¡Òà Nutrition Development Foundation” ¡Ó¡Ñº • ÁÕÃÙ»·Ã§·Ñ¹ÊÁÑ áÊ´§ÍÍ¡¶Ö§¤ÇÒÁ¤Ô´ÊÌҧÊÃä�� áÅШ´¨Ó§‹Ò • ¾ÔÁ¾¼Å§Ò¹μÃÒÊÑÞÅѡɳÅ§º¹¡ÃдÒÉ ¢¹Ò´ A4 ¾ÃŒÍÁ͸ԺÒÂá¹Ç¤ÇÒÁ¤Ô´ã¹¡ÒÃÍ͡Ẻ´ŒÒ¹Å‹Ò§ • à¢Õ¹ª×èÍ-¹ÒÁÊ¡ØÅ ·ÕèÍÂÙ‹à¾×èÍ¡ÒÃμÔ´μ‹Í (ʶҹ·ÕèÈÖ¡ÉÒ Ê¶Ò¹·Õè·Ó§Ò¹ ËÁÒÂàÅ¢â·ÃÈѾ·áÅÐÍÕàÁŏ) ¡Ó¡Ñº¼Å§Ò¹ • ÊÒÁÒöʋ§¼Å§Ò¹ä´ŒäÁ‹¨Ó¡Ñ´¨Ó¹Ç¹ ¼ÙŒä´ŒÃѺÃÒ§ÇÑÅÂÔ¹ÂÍÁ໚¹¼ÙŒÃѺÀÒÃСÒè‹ÒÂÀÒÉÕà§Ô¹ä´ŒËÑ¡ ³ ·Õ訋Ò áÅÐËÃ×ÍÀÒÉÕÍ×è¹æ ã¹ÍÑμÃÒ·Õè¡®ËÁÒ¡Ó˹´ â´Â ¤Ô ´ ¨Ò¡ÁÙ Å ¤‹ Ò ¢Í§ÃÒ§ÇÑ Å ·Õè ä ´Œ ÃÑ º ¼Å§Ò¹·Õè ä ´Œ ¶× Í à»š ¹ ¡ÃÃÁÊÔ · ¸Ôì ¢ ͧÁÙ Å ¹Ô ¸Ô ¾Ñ ² ¹ÒâÀª¹Ò¡Òà ʋ § ¼Å§Ò¹ÀÒÂã¹ÇÑ ¹ ·Õè

31 ÊÔ§ËÒ¤Á 2552

√“ß«—≈™π–‡≈‘» 10,000 ∫“∑ μâÕß°“√√“¬≈–‡Õ’¬¥‡æ‘Ë¡‡μ‘¡μ‘¥μàÕ

§ÿ≥¡¬ÿ√’ ·ª≈߇ߑπ ‚∑√. 0-2348-7000 μàÕ 4343 „π«—π·≈–‡«≈“√“™°“√ Ê‹§¼Å§Ò¹ä´Œ·Õè ÊÁÒ¤ÁâÀª¹Ò¡ÒÃáË‹§»ÃÐà·Èä·ÂÏ âç¾ÂÒºÒÅà·¾¸ÒÃÔ¹·Ã 3850 ¶¹¹¾ÃÐÃÒÁ 4 á¢Ç§¾ÃÐ⢹§ à¢μ¤Åͧàμ ¡ÃØ§à·¾Ï 10110 ªï∑’Ë 43 ©∫—∫∑’Ë 4 μÿ≈“§¡ - ∏—𫓧¡ 2551

Nutrition_p47_pro1.indd Sec1:47

47

6/18/09 10:51:03 PM


Nutrition

Website

‡«Á∫‰´μå ¡“§¡‚¿™π“°“√·Ààߪ√–‡∑»‰∑¬œ

www.nutritionthailand.or.th

μÅÍ´ÃÐÂÐàÇÅÒ¡Ç‹Ò 40 »‚ ·Õ輋ҹÁÒ ÊÁÒ¤ÁâÀª¹Ò¡Òà áË‹§»ÃÐà·Èä·Âã¹¾ÃÐÃÒªÙ»¶ÑÁÀÊÁà´ç¨¾ÃÐà·¾ÃÑμ¹ÃÒªÊØ´ÒÏ ÊÂÒÁºÃÁÃÒª¡ØÁÒÃÕ ¡ŒÒÇà´Ô¹ä»μÒÁÇÑμ¶Ø»ÃÐʧ¤ ËÅÑ¡Íѹ໚¹ÀÒáԨÊÓ¤ÑÞμÑé§áμ‹àÁ×èÍáá¡‹ÍμÑé§ÊÁÒ¤ÁÏ ¹Ñ蹤×Í ¡ÒúÓà¾ç Þ »ÃÐ⪹ ´Œ Ò ¹ÍÒËÒÃáÅÐâÀª¹Ò¡ÒÃâ´Â¡Òà ʋ § àÊÃÔ Á ÇÔ · ÂÒ¡ÒÃãËŒ à ¨ÃÔ Þ ¡Œ Ò Ç˹Œ Ò áÅÐà¼Âá¾Ã‹ ¤ ÇÒÁÃÙŒ á ¡‹ »ÃЪҪ¹¼‹Ò¹Ê×èÍμ‹Ò§æ ³ Çѹ¹Õé ÊÁÒ¤ÁÏ Âѧ¤§ÂÖ´ÁÑè¹»³Ô¸Ò¹´Ñ§¡Å‹ÒÇÍ‹ҧ ÁÑ蹤§áÅÐμ‹Íà¹×èͧ ¨Ö§ä´Œ¾Ñ²¹Òª‹Í§·Ò§Ê×èÍÊÒÃãËÁ‹´ŒÒ¹ÍÒËÒà Í͹䬏¼‹Ò¹àÇçºä«μ www.nutritionthailand.or.th à¾×èÍ ª‹ÇÂãËŒ¡Ò÷Ó˹ŒÒ·Õè໚¹Èٹ¡ÅÒ§¢ŒÍÁÙÅÇÔªÒ¡Ò÷ҧÍÒËÒà áÅÐâÀª¹Ò¡ÒÃÁÕ ¤ ÇÒÁÊÁºÙ à ³ á ººÁÒ¡¢Öé ¹ ÍÕ ¡ ·Ñé § ¡Òà áÅ¡à»ÅÕè  ¹¤ÇÒÁÃÙŒ ·Õè à »š ¹ »˜ ¨ ¨Ø ºÑ ¹ ÃÐËÇ‹ Ò §ÁÇÅÊÁÒªÔ ¡ áÅÐ ¼ÙŒà¡ÕèÂÇ¢ŒÍ§ÁÕ¤ÇÒÁÊдǡ ÃÇ´àÃçÇ áÅзѹ¡ÑºÊ¶Ò¹¡Òó¢Í§ âÅ¡ã¹ÂؤâÅ¡ÒÀÔÇÑμ¹ 48

»Ÿπ¬å√«¡¢âÕ¡Ÿ≈«‘™“°“√∑“ߥâ“πÕ“À“√ ·≈–‚¿™π“°“√‡æ◊ËÕ ÿ¢¿“æ

ÊÁÒªÔ¡ÊÒÁÒöࢌÒÁÒÈÖ¡ÉÒËÒ¢ŒÍÁÙŨҡ “ÊÒÃй‹ÒÃÙŒ” «Öè § ໚ ¹ ºÃÔ ¡ ÒÃ˹Öè § ¢Í§àÇç º ä«μ ·Õè ÁÕ ¡ ÒÃ¨Ñ ´ ËÁÇ´ËÁÙ‹ à ¡Ãç ´ ¤ÇÒÁÃÙŒ · Ò§´Œ Ò ¹ÍÒËÒÃáÅÐâÀª¹Ò¡ÒÃμÒÁ¤ÇÒÁʹ㨢ͧ ÊÁÒªÔ¡ »ÃСͺ´ŒÇÂËÁÇ´ÍÒËÒÃà¾×èÍÊØ¢ÀÒ¾ ¡ÒÃÍÍ¡¡ÓÅѧ ¡ÒÂà¾×èÍÊØ¢ÀÒ¾ ÂÒáÅÐÍÒËÒÃàÊÃÔÁ ÍØ»¡Ã³à¤Ã×èͧ㪌μÃǨ ÊØ¢ÀÒ¾ áÅл¡Ô³¡Ð ¹Í¡¨Ò¡¹ÕéÀÒÂã¹àÇçºä«μ ÂѧãËŒºÃÔ¡Òà ¤ÇÒÁÃÙŒã¹ÃٻẺ¢Í§ÀÒ¾à¤Å×è͹äËÇ ËÃ×Í VDO Streaming ÍÕ¡´ŒÇ »Ÿπ¬å°≈“ß°“√·≈°‡ª≈’Ë¬π§«“¡√Ÿâ·≈–· ¥ß§«“¡§‘¥ ‡ÀÁπ∑“ߥâ“πÕ“À“√·≈–‚¿™π“°“√

ÊÁÒªÔ¡ÊÒÁÒöμÑ駻ÃÐà´ç¹«Ñ¡¶ÒÁã¹ÊÔ觷ÕèμŒÍ§¡ÒèзÃÒº ·Ò§´Œ Ò ¹ÍÒËÒÃáÅÐâÀª¹Ò¡ÒÃã¹Ê‹ Ç ¹¢Í§ “¶ÒÁ-μͺ”

«“√ “√‚¿™π“°“√

R1_Nutrition_p48-49_pro1.indd Sec1:48

6/22/09 11:21:09 PM


ÊÁÒ¤ÁÏ ÁÕ¼ÙŒ·Ã§¤Ø³ÇزԷÕèÁÕ¤ÇÒÁÃÙŒ¤ÇÒÁàªÕèÂǪÒÞ੾ÒÐ ´Œ Ò ¹ÁÒ¡ÁÒ·Õè Ê ÒÁÒö䢢Œ Í §ã¨¢Í§ÊÁÒªÔ ¡ä´Œ ·Ø ¡ àÃ×è Í § äÁ‹ Ç‹ Ò ¨Ð໚ ¹ ·Ò§´Œ Ò ¹ÇÔ ª Ò¡Òà ÈÑ ¾ · · Ò§ÍÒËÒÃáÅÐ âÀª¹Ò¡Òà ËÃ×ÍáÁŒ¡ÃзÑè§àÃ×èͧ·ÑèÇæ ä»·ÕèÊÁÒªÔ¡ÁÕ¤ÇÒÁ ʹ㨠«“√ “√‚¿™π“°“√ÕÕπ‰≈πå (E-Magazine)

àÇçºä«μ Nutritionthailand ÁͺºÃÔ¡ÒþÔàÈÉá¡‹ ÊÁÒªÔ¡´ŒÇºÃÔ¡ÒÃÇÒÃÊÒÃâÀª¹Ò¡ÒÃÍ͹䬏 «Öè§ÊÁÒªÔ¡ ÊÒÁÒöࢌÒÁÒÍ‹Ò¹ÇÒÃÊÒéºÑºàμçÁàÅ‹ÁÅ‹ÒÊØ´ËÃ×Í©ºÑºÂŒÍ¹ ËÅѧ䴌μÅÍ´àÇÅÒ ¾ÃŒÍÁ·Ñé§ÊÒÁÒö´ÒǹâËÅ´ÇÒÃÊÒÃä´Œ â´ÂäÁ‹μŒÍ§àÊÕ¤‹Ò㪌¨‹ÒÂã´ æ ·Ñé§ÊÔé¹ ™àÕß∑“ß°“√ ◊ËÕ “√√–À«à“ß ¡“§¡œ °—∫ ¡“™‘°

¹Í¡¨Ò¡¡ÒÃ໚ ¹ ÈÙ ¹  à ÇÁ¤ÇÒÁÃÙŒ á ÅŒ Ç àÇç º ä«μ Nutritionthailand Âѧ໚¹ª‹Í§·Ò§¡ÒáÃШÒ¢‹ÒÇÊÒà ¤ÇÒÁà¤Å×è Í ¹äËÇã¹áǴǧÍÒËÒÃáÅÐâÀª¹Ò¡Òèҡ ÊÁÒ¤Á Ï ä»ÊÙ‹ÊÁÒªÔ¡ ÍÒ·Ôઋ¹ â¤Ã§¡ÒÃà¾×èÍÊØ¢ÀÒ¾ μ‹Ò§ æ §Ò¹¹Ô·ÃÃÈ¡Ò÷Õèà¡ÕèÂÇ¢ŒÍ§¡ÑºÇ§¡ÒÃÍÒËÒÃáÅÐ âÀª¹Ò¡Òà §Ò¹ÊÑÁÁ¹ÒËÃ×Í¡ÒûÃЪØÁ·Ò§ÇÔªÒ¡Òà ໚¹μŒ¹ °“√´◊ÈÕ › ¢“¬ ÕÕπ‰≈πå: http://shop.nutritionthailand.or.th

à¾×èÍ໚¹¡ÒÃແ´ª‹Í§·Ò§ãËŒ¤ÇÒÁÊдǡᡋÊÁÒªÔ¡ã¹ ¡Ã³Õ·ÕèμŒÍ§¡Òë×éÍ˹ѧÊ×Í àÍ¡ÊÒÃÊÔ觾ÔÁ¾ ËÃ×Í DVD ¡ÒûÃЪØÁÇÔªÒ¡Òà ã¹àÇçºä«μ¨Ö§à»´ºÃÔ¡ÒþÔàÈÉã¹Ê‹Ç¹ ¢Í§ “«×éÍ - ¢Ò Í͹䬏” â´ÂÁÕÃÒÂÅÐàÍÕ´à¡ÕèÂǡѺ ÊÔ¹¤ŒÒáμ‹ÅЪÔé¹ â´Â੾ÒÐ DVD ¹Ñé¹ ÊÁÒªÔ¡ËÃ×ͼٌʹ㨠ÊÒÁÒö´ÒǹâËÅ´´ÙμÑÇÍ‹ҧà¹×éÍËÒã¹ DVD áÅÐÊÑ觫×éÍ ä´Œ·Ñ¹·Õ·Ò§Í͹䬏  ‘∑∏‘ª√–‚¬™πå∑’Ë ¡“™‘° ¡“§¡œ ®–‰¥â√—∫

ÊÁÒªÔ¡ÊÁÒ¤ÁâÀª¹Ò¡ÒÃáË‹§»ÃÐà·Èä·Â Ï ¹Í¡ à˹×ͨҡ·Õèä´ŒÃѺÊÔ·¸ÔìࢌÒËÇÁ¡Ô¨¡ÃÃÁμ‹Ò§æ ·ÕèÊÁÒ¤ÁÏ ¨Ñ´¢Öé¹áÅÐÁÕÊÔ·¸Ôìàʹ͢ŒÍ¤Ô´àËç¹à¡ÕèÂǡѺ¡ÒôÓà¹Ô¹¡Òà ¢Í§ÊÁÒ¤ÁÏ ÂѧÁÕÊÔ·¸Ôìä´ŒÃѺÊÇÑÊ´Ô¡ÒÃμ‹Ò§æ ·ÕèÊÁÒ¤ÁÏ ¨Ñ´ãËŒÁÕ¢Öé¹ã¹Í¹Ò¤μ áÅзÕèÊÓ¤ÑÞä´ŒÃѺÊÔ·¸Ôì໚¹ÊÁÒªÔ¡ àÇçºä«μ Nutritionthailand â´ÂÍÑμâ¹ÁÑμÔ â´ÂÊÒÁÒÃ¶à¢ŒÒ ÁÒÍ‹Ò¹¢‹ÒÇ»ÃЪÒÊÑÁ¾Ñ¹¸ Í‹Ò¹áÅдÒǹâËÅ´ÇÒÃÊÒÃ

âÀª¹Ò¡ÒéºÑºàμçÁ (E-Magazine) μÅÍ´¨¹ä´ŒÃѺ¡ÒÃᨌ§ àμ×͹¼‹Ò¹ÍÕàÁÅŏàÁ×èÍʶҹÀÒ¾¡ÒÃ໚¹ÊÁÒªÔ¡ã¡ÅŒËÁ´Å§ à¾×èÍ ãËŒÊÁÒªÔ¡ÊÒÁÒöμ‹ÍÍÒÂØä´Œ·Ñ¹àÇÅÒáÅÐÃÑ¡ÉÒÊÀÒ¾ÊÁÒªÔ¡ä´Œ Í‹ҧμ‹Íà¹×èͧ ÊÁÒ¤ÁÏ ¨Ö§¢ÍàªÔުǹãËŒÊÁÒªÔ¡·Ø¡·‹Ò¹à¢ŒÒä»àÂÕèÂÁªÁáÅР㪌§Ò¹àÇçºä«μ Nutritionthailand ·Ò§ÊÁÒ¤ÁÏ ÂÔ¹´ÕÃѺ¤ÓμÔªÁ áÅÐËÃ×Í¢ŒÍàʹÍá¹Ð à¾×è͹ÓÁÒ»ÃѺ»ÃاáÅоѲ¹ÒàÇçºä«μãËŒ ໂ›ÂÁä»´ŒÇÂà¹×éÍËÒÊÒÃР໚¹Èٹ¡Åҧ㹡ÒÃáÅ¡à»ÅÕ蹤ÇÒÁÃÙŒ áÅÐà·¤â¹âÅÂÕ´ŒÒ¹ÍÒËÒÃáÅÐâÀª¹Ò¡Ò÷Õè·Ñ¹ÂؤÊÁÑ áÅÐ·Ó Ë¹Œ Ò ·Õè à ¼Âá¾Ã‹ ¤ ÇÒÁÃÙŒ ·Õè à »š ¹ »ÃÐ⪹ ã ËŒ á ¡‹ Ê ÁÒªÔ ¡ áÅÐ ¼ÙŒÊ¹ã¨·ÑèÇä»ÊÁ´Ñ§»³Ô¸Ò¹·ÕèμÑé§äÇŒ ã¹·ŒÒ¹Õé ·Ò§ÊÁÒ¤ÁÏ ¨Ðᨌ§¢‹ÒÇãËŒÊÁÒªÔ¡ä´ŒÃѺ·ÃÒº ¤ÇÒÁ¤×ºË¹ŒÒ¢Í§àÇçºä«μ Nutritionthailand ã¹âÍ¡ÒÊμ‹Íä» ÊÓËÃѺ¼ÙŒ·ÕèμŒÍ§¡ÒÃÊÁѤÃ໚¹ÊÁÒªÔ¡ÊÁÒ¤ÁâÀª¹Ò¡ÒÃáË‹§ »ÃÐà·Èä·ÂÏ ÊÒÁÒö´ÒǹâËŴẺ¿ÍÏÁãºÊÁѤü‹Ò¹·Ò§ àÇçºä«μä´ŒáÅŒÇÇѹ¹Õé·Õè www.Nutritionthailand.or.th ªï∑’Ë 43 ©∫—∫∑’Ë 4 μÿ≈“§¡ - ∏—𫓧¡ 2551

R1_Nutrition_p48-49_pro1.indd Sec1:49

49

6/22/09 11:21:09 PM


¼È.´Ã.·Ô¾Âà¹μà ÍÃÔ»μԾѹ¸ ¤³ÐÊËàǪÈÒÊμÏ ¨ØÌÒŧ¡Ã³ÁËÒÇÔ·ÂÒÅÑ 154 «Í¨ØÌÒÏ 12 ¶¹¹¾ÃÐÃÒÁ 1 á¢Ç§ÇѧãËÁ‹ à¢μ»·ØÁÇѹ ¡ÃØ§à·¾Ï 10330 â·ÃÈѾ· 0 2218 1069 Á×Ͷ×Í 081 634 2466 â·ÃÊÒà 0 2218 1076, ÍÕàÁŏ tipayanate@yahoo.com

R1_Nutrition_p50_pro1.indd Sec1:5

6/22/09 11:25:04 PM


Nutrition_p51_pro1.indd Sec1:5

6/19/09 11:35:28 AM


R1_Nutrition_p52_pro1.indd Sec1:52

6/22/09 11:27:08 PM



Nutrition_OCT_DEC51