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Puerto Rico NASA EPSCoR Research Infrastructure Development Program

PR

Silver-Graphene Nanocomposite to Combat Drug-resistant Bacteria Functionalized nanoparticles can offer novel solutions for the post-antibiotic era. In this context, we developed a nanocomposite of silver nanoparticles decorated with graphene quantum dots (Ag GQDs) and functionalized with polyethylene glycol. This nanocomposite inhibits the growth of Gram-positive S. aureus and Gram-negative P. aeruginosa bacteria, which are commonly isolated from microbial infections in wounds. The concentration required to inhibit both types of bacterial strains is well below the concentration that would affect the mammalian cell viability, being therefore biocompatible. The effectiveness of the composite is due to a synergistic effect in which the GQDs facilitate the internalization of the silver nanoparticles into the bacteria, thus reducing the overall concentration of silver required to produce the bactericide effect. These results suggest that Ag-GQDs can be used in the fabrication of antibacterial ointments, self sterile textiles, and sterile personal care products. The next phase is to independently validate the results and develop antibacterial products based on Ag-GQDs. The following provisional invention patent was recently submitted to the U.S. Patent and Trademark Office: “Method for the Synthesis and Functionalization of Nanoparticle - Graphene Quantum Dots Nanocomposites by a Plasma Assisted Approach”, Filing Number 62/145559. Researchers from University of Puerto Rico patented an approach to diamond induction by employing iron nanoparticles to induce the synthesis of diamond on molybdenum, silicon, and quartz substrates. (Patent #: US 8,784,766 B1– Issue Date – July 22, 2014).

www.nasa.gov/epscor/stimuli

NASA EPSCoR Stimuli 2014-15

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EPSCoR Stimuli 2014-15  

NASA Office of Education’s Aerospace Research & Career Development (ARCD) is pleased to release NASA EPSCoR Stimuli, a collection of univers...

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