Page 1

SHORT COURSES: February 4-5 | CONFERENCE: February 4-8 | EXHIBITS: February 6-8

SLAS2017

Preliminary Program Register by December 19 for advance discounts: SLAS2017.org

Premier Sponsor:

#SLAS2017


SLAS2017 PRELIMINARY PROGRAM

Table of Contents

3 WHY YOU SHOULD ATTEND SLAS2017 4 WHAT’S NEW AT SLAS2017 5 SCIENTIFIC PROGRAM 7 KEYNOTE SPEAKERS 7 ASSAY GUIDANCE WORKSHOP FOR HIGH-THROUGHPUT SCREENING AND LEAD DISCOVERY

8 SHORT COURSES 12 CONFERENCE-AT-A-GLANCE 16 NETWORKING 17 SLAS MEMBER CENTER 18 SLAS SCIENTIFIC JOURNALS 19 SLAS SPECIAL INTEREST GROUPS 19 CELEBRATE EXCELLENCE 2  0 CAREER CONNECTIONS 21 EXHIBITION 24 REGISTRATION AND HOTEL ACCOMMODATIONS 26 SLAS BOARD OF DIRECTORS AND COMMITTEES 27 SPONSORS SLAS2017.ORG #SLAS2017

2


AT SLAS2017 Life sciences research is evolving at a lightning-fast pace. CRISPR, flow cytometry, cellular biosensors, bioprinting, digital and droplet microfluidics, exploring the dark genome, and physiological-relevant models are but a few of the emerging areas that are changing the landscape on an almost daily basis. Attending SLAS2017 enlightens you to the latest research, peer perspectives and tools you need to stay ahead of the curve.

HEAR lessons learned and best practices from the world’s leading life sciences researchers

BUILD an expansive network of peers who can be looked to year-round to provide insight, answers and feedback

SEE the latest tools and technologies from more than 300 leading providers participating in the SLAS2017 Exhibition

FORTIFY your career path with education and mentoring opportunities in SLAS Career Connections

BOLSTER your knowledge through an array of peer-selected technical presentations, workshops, Short Courses and scientific posters delivered in the SLAS2017 educational program

GET INSPIRED with informative and inspirational keynotes

SLAS2017 is produced by life scientists for life scientists. Don’t miss this unique annual opportunity to fast-track your knowledge and professional connections to make yourself a more valuable asset to your organization. See complete event details at SLAS2017.org.

SLAS2017.ORG #SLAS2017

3


What’s New at SLAS2017 SPECIAL SESSIONS

Regenerative Medicine: Next Generation Treatments SESSION CHAIRS: G. Sitta Sittampalam, National Center for Advancing Translational Sciences, National Institutes of Health; and Marcie Glicksman, ORIG3N, Inc. Regenerative medicine is having a big impact on the future of medicine. Developments in stem cell technology, tissue engineering and molecular biology are pushing the frontiers of medicine by enabling cures through the use of cellular therapies. The next decade will see the rapid development of treatments that will employ human iPS cells, drugs and biologics as substrates for therapies in acute and chronic diseases. In this session, presentations addresses recent advances in the generation, standardization, characterization and the mechanistic behavior of stem cells and their applications in regenerative medicine.

NEW SPECIAL INTEREST GROUP: ULTRA-HIGH-THROUGHPUT SCREENING (uHTS)

Members of the uHTS SIG will work together to improve the quality of uHTS data, the ease of use of uHTS automation systems and the exchange of best practices to further the initial stages of drug discovery to ultimately help patients. The uHTS SIG convenes for the first time at SLAS2017 as a forum for operators and managers of uHTS systems to present/discuss innovation, case studies and daily operations to build a community of uHTS researchers and professionals.

TUESDAY EVENING CELEBRATION AT THE NEWSEUM (SEE PAGE 16)

Whose Responsibility is Research Reproducibility? SESSION CHAIRS: Lenny Teytelman, Protocols.io; Cathy Tralau-Stewart, University of California, San Francisco There is a broad consensus among academic and industry researchers, funders, and other stakeholders that increasing reproducibility of published research is an important goal. However, questions of who should be responsible for validating research results are tricky. This panel features a conversation with both industry and academic perspectives on this challenging issue.

FUND RUN…ON YOUR MARK, GET SET, GO! Tuesday | February 7 | 6:30 am Start Sponsored by

NEW SHORT COURSES

One new full-day course and four new halfday courses shine an in-depth light on the latest in scientific technology. Offerings include: Pharmacology in Drug Discovery and Development: New Lives for Receptors as Drug Targets Through Allostery and Biased Signaling (full-day) ■■ Data Analytic Concepts for High-Throughput Screening & Biomarker Applications (half-day) ■■ An Introduction to Mass Spectrometry and its Applications within Drug Discovery (half-day) ■■ Introduction to Flow Cytometry (half-day) ■■ Advanced Flow Cytometry (half-day) ■■

SLAS2017.ORG #SLAS2017

The second annual SLAS FUNd Run benefits the SLAS Educational Fund. Whether a competitive runner or just looking for some casual exercise, mark your calendar to participate in the 2017 SLAS FUNd Run on the morning of Tuesday, February 7. Advance registrants who make a $25 contribution to the SLAS Educational Fund receive an exclusive 2017 SLAS FUNd Run t-shirt.

4


Scientific Program 1

The SLAS2017 scientific program represents original research, case studies, and innovative technology advancement in the life sciences that will inspire, challenge and accelerate your own research. The program includes 140 podium presentations across seven in-depth tracks, hundreds of posters, and 21 Short Courses. See complete details on SLAS2017.org.

ADVANCES IN BIOANALYTICS, BIOMARKERS AND DIAGNOSTICS

Track Chair(s): Dieter Drexler, Bristol-Myers Squibb and Melanie Leveridge, GlaxoSmithKline n Label-Free

Bioanalytical Techniques for Hit Identification and Optimization Session Chair: Melanie Leveridge, GlaxoSmithKline n Targeted

Biomarker Analysis

Session Chair: Dieter Drexler, Bristol-Myers Squibb n Target Identification After Phenotypic Screens Session Chair: Shaun McLoughlin, AbbVie Laboratories

2

ASSAY DEVELOPMENT AND SCREENING

Track Chair(s): Cathy Tralau-Stewart, University of California, San Francisco and Edward Ainscow, Carrick Therapeutics n Phenotypic

and High-Content Screening Assays

Session Chair: Susanne Heynen-Genel, Sanford Burnham Prebys Medical

Discovery Institute n Biochemical

and Biophysical Screening

Session Chair: Razvan Nutiu, Novartis Institutes for Biochemical Research n Cellular Biosensors and Genome Editing in Screening Assay Design Session Chair: Ralph Garippa, Memorial Sloan Kettering Cancer Center n Assay Platforms for Biologics Session Chair: Rob Howes, MedImmune n Screening the Undruggable Session Chair: John Lazo, The University of Virginia n Rational Screen Design Session Chair: Edward Ainscow, Carrick Therapeutics

3

AUTOMATION AND HIGH-THROUGHPUT TECHNOLOGIES

Track Chair(s): Craig Schulz, Amgen and Taosheng Chen, St. Jude Children’s Research Hospital n High-Content

and High-Throughput Automation

Session Chair: Louis Scampavia, The Scripps Research Institute n Screening Automation: Modular Systems vs. Highly Integrated Systems Session Chair: Paul Anderson, The Genomics Institute of the Novartis Research Foundation n Automating Phenotypic and Target Based Discovery using Parallel Automated Approaches

Session Chair: Robin Felder, The University of Virginia n Using

Physiologically-Relevant Models for Automated Screens

Session Chair: Shane Horman, The Genomics Institute of the Novartis Research Foundation n Automating

Novel Analytical Tools for PKA, Drug-Drug Combination and Synergy Assays, Drug Repurposing

Session Chair: Wei Zheng, National Center for Advancing Translational Sciences, National Institutes of Health n In-House

Automation: Devices and Software Developed Internally

Session Chair: Rob Keyser, Calico Life Sciences

SLAS2017.ORG #SLAS2017

5


4

CELLULAR TECHNOLOGIES

Track Chairs: John Doench, The Broad Institute and Benjamin Haley, Genentech n Advances

in Genome Editing Technologies

Session Chair: Gregory Davis, MIlliporeSigma n Development

of Cellular Models for Phenotypic Screening

Session Chair: Joel Klappenbach, Merck & Co., Inc. n Genetic

Screens for Target Discovery and Validation

Session Chair: Lou Staudt, National Cancer Institute

5

DATA ANALYSIS AND INFORMATICS

Track Chairs: Lenny Teytelman, Protocols.io and Margaret DiFilippo, Dotmatics n Informatics

for Translational Medicine

Session Chair: Rajarshi Guha, National Center for Advancing Translational Sciences,

National Institutes of Health n The

Challenges and Benefits of Collaboration

Session Chair: Farida Kopti, Merck & Co., Inc. n Rethinking

Research Workflow and Utilizing Data to Improve Reproducibility

Session Chair: Tim Gardner, Ryffin n Making

Scientific Data 100x Easier to Use

Session Chair: Megean Schoenberg, Merck & Co., Inc. n Informatics

of Drug Design and Compound Life Cycle Management

Session Chair: Dmitry Lupyan, Schrodinger n The

Digital Dark Hole: Publishing Large-Scale Data and Analysis

Session Chair: Laurie Goodman, GigaScience

6

DRUG TARGET STRATEGIES

Track Chairs: David Swinney, iRND3 and Chun-wa Chung, GlaxoSmithKline n Hard

Targets: Success Through Collaborations

Session Chair: Chun-wa Chung, GlaxoSmithKline n Uniting

Phenotypic and Target Based Drug Discovery

Session Chair: Fabien Vincent, Pfizer Inc. n Non-Traditional

Modalities as Therapeutics

Session Chair: Stephen Hale, Ensemble Therapeutics

7

MICRO- AND NANOTECHNOLOGIES

Track Chairs: Sindy Tang, Stanford University and Andrew deMello, Institute for Chemical and Bioengineering n Digital

and Droplet Microfluidics

Session Chair: Adam Abate, University of California, San Francisco n Perspectives on Commercialization of Integrated Micro and Nanofluidic Devices Session Chair: Sammy Datwani, Labcyte Inc. n Single

Cell Analyses

Session Chair: Daniel Chiu, University of Washington n Making

Micro-Volume Biology Work: Tools, Techniques & Secrets

Session Chair: Daniel Sipes, The Genomics Institute of the Novartis Research Foundation n Bioprinting:

Multidimensional Microscale Cellular/Tissue Engineering

Session Chair: Markus Rimann, Zurich University of Applied Sciences n Microphysiological Systems

Session Chair: Daniel Huh, University of Pennsylvania

Visit SLAS2017.org for complete details on the scientific program, including presentation titles, abstracts, presenter bios and to build your agenda. SLAS2017.ORG #SLAS2017

6


Keynote Presentations

Sponsored By:

Monday | February 6 | 9:00 am Jennifer Lippincott-Schwartz Section Chief of the Cell Biology and Metabolism Branch, NICHD, NIH and NIH Distinguished Investigator

Most recently, Jennifer Lippincott-Schwartz research has focused on the development and use of photoactivatable fluorescent proteins, including the development of photoactivated localization microscopy, (i.e., PALM), a super-resolution imaging technique that enables visualization of molecule distributions at high density at the nano-scale. Her work has been recognized with election to the National Academy of Sciences and the National Institute of Medicine, and with the Royal Microscopy Society Pearse Prize and the Society of Histochemistry Feulgen Prize. She is president of the American Society of Cell Biology for 2014. She serves on the scientific advisory boards of the Howard Hughes Medical Institute, the Weizmann Institute of Sciences, the Searle Scholar Program, and the Salk Institute.

Wednesday | February 8 | 3:45 pm Rachel Swaby Renowned Author of Headstrong: 52 Women Who Changed Science-and the World

Rachel Swaby a freelance writer and editor based in Brooklyn, NY. Her book Headstrong: 52 Women Who Changed Science—and the World came out in 2015. Read more about Swaby in SLAS Electronic Laboratory Neighborhood.

Assay Guidance Workshop for High-Throughput Screening and Lead Discovery Saturday, February 4 8:30 am - 5:30 pm Requires an additional registration fee of $399.

SLAS2017.ORG #SLAS2017

This full-day workshop covers a broad range of critical concepts underlying assay development for high throughput screening (HTS) and lead discovery projects. Many of the methodologies successfully implemented in such projects have been “tribal knowledge” within the pharmaceutical industry and not readily found in a classroom or the literature. This “tribal knowledge” has been developed for decades into detailed chapters within the AGM to facilitate reproducible assays that can identify the most promising compounds for development of molecular probes or clinical candidates for drug discovery and development. An increasing number of researchers are actively developing well validated assays for drug discovery that include phenotypic and biochemical assays for lead optimization. This workshop is designed to disseminate critical information about the implementation of robust assay methods and intended to benefit the entire drug discovery community. Many of the workshop instructors have 20-30 years of experience in the field of drug discovery.

7


Short Courses

Short Courses kick-off SLAS2017 on Saturday-Sunday, February 4-5. This year’s lineup includes five new offerings covering topics such as Data Analytic Concepts for High-Throughput Screening & Biomaker Application and An Introduction to Mass Spectrometry and its Applications Within Drug Discovery. Short Course attendance is limited and requires advance registration and an additional registration fee.

FULL-DAY SHORT COURSES: Saturday | February 4 | 8:30 am - 4:30 pm 3D Cell-Based Assays for Drug De-Risking Cell-based in vitro assays are used throughout the drug discovery and development chain, allowing for highthroughput efficacy but also mechanistic-based toxicity testing. A big challenge however is the translation of in vitro assays towards the in vivo outcome. Physiological relevance is a key parameter to improve the predictive power of cell-based assays. The better we can reflect tissue architecture, composition and function the more predictive an in vitro assay will become. The 3D course covers advances in 3D cell culture technologies, assays and their use in drug discovery and development. Instructors: Helena Hogberg, Center for Alternatives to Animal Testing (CAAT), Johns Hopkins Bloomberg School of Public Health; Jens M. Kelm, InSphero AG

Digital Image Processing and Analysis for the Laboratory Scientist: Theory and Application (Laptop Required) This course takes a practical, hands-on approach to the application of digital image processing and analysis in a life-sciences laboratory. Diverse techniques and applications are covered. Upon completion, the attendee is prepared to apply learned methodologies to their own experimental images to extract relevant information and summarize results. This course is an ideal way to prepare for the SLAS short course Multi Parametric Analysis of High-Content Screening Data. Instructors: Matthew Fronheiser, Mark Russo

Introduction to Laboratory Automation

This course presents a broad introduction to laboratory automation in the R&D laboratory environment (i.e. non-clinical). A general understanding of a laboratory environment is helpful. Instructors: Steven Hamilton, SLAS; James Gill

Lab-on-a-Chip: From Technology to Bioanalysis on Chip

This course is aimed at researchers who are interested in learning more about new developments in the technology behind lab-on-a-chip systems. This course is a “how-to” primer that could form the basis for the development of prototypes having integrated functions for a variety of purposes. Instructors: Sabeth Verpoorte, Groningen Research Institute of Pharmacy, University of Groningen; Johan Nilsson, Lund University; Jörg P. Kutter, University of Copenhagen

SLAS2017.ORG #SLAS2017

8


FULL-DAY SHORT COURSES: Sunday | February 5 | 8:30 am - 4:30 pm Affinity-based, Biophysical Methods for Screening and Mechanistic Studies: How to Effectively Use a Growing Biophysical Toolbox to Find and Characterize Chemical Leads

The course will be delivered in two parts. The first section includes a series of brief high-level presentations concerning the biophysical theory behind each technology and their application in lead finding, hit validation as well as more in depth mechanistic studies. The second section presents some challenges on how to effectively apply those technologies by looking at a range of common scenarios from different phases of lead discovery. Instructors: Christine C. Genick, Novartis; Stefan Geschwindner, Discovery Sciences, AstraZeneca R&D Mรถlndal

Data Management in the Age of Big Data, Mobile and the Cloud

This data management course provides decision makers and practitioners from bio-pharma, healthcare and academia with a comprehensive overview of IT trends in laboratory automation, data management, and systems integration. It highlights the current hot fields in the area of data management, big data, cloud computing and mobile technologies. This course provides crucial guidance for assessing how these new technologies fit into your laboratory data landscape. The instructor supplies practical guidance and examples for how to apply these techniques to laboratory workflows. Instructors: Burkhard Schaefer, BSSN Software GmbH

Derivation, Maintenance and Characterization Techniques for Human iPS Cells Used in Drug Discovery and Disease Modeling

This course provides an overview on stem cell biology and the laboratory techniques used to derive and maintain human induced pluripotent stem cells (iPS). Additional topics include the current state of stem cell research, manual and semi-automated reprogramming and maintenance techniques, and characterization assays and HTS strategies. Instructors: Kamal Garcha, GFY Biotech Consulting; David J. Kahler, NYU High-Throughput Biology Core

Establishing Cell-Based Assays for Screening

This course describes developing standard procedures for handling cultured cells to set up cell-based assays, techniques for measuring cell health and the pathways leading to cytotoxicity, developing siRNA screening assays and an overview of various GPCR screening methods. Instructors: Terry L. Riss, Promega Corporation; Geoffrey Bartholomeusz, University of Texas MD Anderson Cancer Center; Eric N. Johnson, Wuxi AppTec; Lisa Minor, In Vitro Strategies, LLC

High-Content Screening: An Introduction to Instrumentation, Assay Development, Screening, Image and Data Analysis High-content screening is a powerful technology platform for implementing functional cell-based assays that allow truly multi-parametric analysis in the physiological context of intact cells. This course provides an introductory level overview of the state-of-the-art components of HCS together with some showcases of high-content screens in industry and academia. Instructors: Steffen Jaensch, Janssen R&D, Pharmaceutical Companies of Johnson & Johnson; Eberhard Krausz, VIB - Discovery Sciences

Liquid Handling Essentials (Interactive Course)

This course is designed to introduce important concepts that affect liquid handling performance so that the overall quality and efficiency remain high. With a balanced mix of discussions and activities, this course will focus on applying key practices on live systems and measuring performance metrics. Instructors: Dana Campbell, Artel, Inc.; Nathaniel Hentz, NC State University BTEC; Lisa Knapp, Agilent Technologies

SLAS2017.ORG #SLAS2017

9


FULL-DAY SHORT COURSES: Sunday | February 5 | 8:30 am - 4:30 pm | continued Multi Parametric Analysis of High-Content Screening Data (Laptop Required)

A hands-on course for analyzing multiparametric data typically extracted from high content images using the open source platform KNIME. This course shows how to transform complex datasets into biological insights using advanced data mining techniques without programming. Note: Attending Digital Imaging Processing and Analysis for the Laboratory Scientist: Theory and Application on Saturday, February 4, will help prepare attendees for this course. Instructors: Marc Bickle, MPI-CBG; Antje Janosch, MPI-CBG

Next Generation Sequencing Technology Fundamentals and Applications

Next generation sequencing (NGS) technologies has revolutionized genomics. It has created a novel set of applications and industries in such diverse fields as agriculture, the environment, human origins, infectious diseases and human health. Besides introducing basic concepts, this course provides a glimpse of future through ground-breaking applications. Instructors: Abizar Lakdawalla, Proxeom; Dawei Lin, NIH/NIAID

Pharmacology in Drug Discovery and Development: New Lives for Receptors as Drug Targets Through Allostery and Biased Signaling (NEW)

This course discusses new ideas about efficacy (efficacy fingerprints, biased signaling) and allosteric receptor function to improve definition and quantification of GPCR drug activity, better target drug activity (i.e. pathway vs target validation) and predict therapeutic activity profiles. Specifically, methods to guide SAR for biased signaling and allosteric ligand activity are featured. Instructors: Terry Kenakin, UNC School of Medicine

Sample Management: Best Practice, Trends and Challenges

This course provides current status and considered best practice in the discipline of sample management. It focuses on the traditional aspects of compound management (including how to maintain and measure quality of compounds) but covers the synergies and differences in managing biologics. Consideration is given to key challenges and future directions. With the growth and interest in biological sample management the course has been expanded to cover this discipline. Instructors: Susan Crimmin, GlaxoSmithKline; Kathi E. Shea, Brooks BioStorage Technologies

HALF-DAY SHORT COURSES: Sunday | February 5 | 8:30 am - 12:00 pm Data Analytic Concepts for High-Throughput Screening and Biomarker Applications (NEW)

This course provides an overview of some data analytic concepts such as the MSR (minimum significant ratio) and error-rate estimation for HTS, and FDR (false discovery rate), multivariate predictive modeling process and performance evaluation for high-dimensional high-omics data, and some statistical considerations for biomarker assay evaluations. Instructor: Viswanath Devanarayan, AbbVie, Inc.

Introduction to Flow Cytometry (NEW)

This course provides an introduction to the fundamentals and applications of flow cytometry across a range of life science applications. Flow cytometry has become a go-to technology for single cell analysis and has also entered the world of high-throughput screening. Those who want to learn about the fundamentals of how flow cytometry works, and the background to the field and applications will find this course attractive. Instructors: John Nolan, Scintillon Institute; Paul Robinson, Purdue University

Lead Generation: A Critical Discussion of Hypothesis and Empirical Strategies

This course provides a framework for discussing drug discovery screening strategies with an emphasis on effectively using and integrating phenotypic-based and target-based screening approaches. The goal of this course is to provide a broader context of the drug discovery process and to help understand how to best utilize existing knowledge, tools and technologies. Instructors: Jonathan Lee, Eli Lilly; David C. Swinney, Institute for Rare and Neglected Diseases Drug Discovery

SLAS2017.ORG #SLAS2017

10


HALF-DAY SHORT COURSES: Sunday | February 5 | 1:00 - 4:30 pm Advanced Flow Cytometry (NEW)

This advanced course expands into advanced areas many of which are leading-edge applications or expansions of current technology. These areas includes high-throughput screening, advanced multiparameter analysis, spectral technologies, cell sorting and clinical and environmental (microbial) applications for example. This course provides the audience with a strong background level of understanding of the technology, current limitations, and the future opportunities. Instructors: John Nolan, Scintillon Institute; Paul Robinson, Purdue University

An Introduction to Mass Spectrometry and its Applications Within Drug Discovery (NEW)

This short course provides an introduction to mass spectrometry and the range of potential applications within drug discovery. This course covers the basic principles of mass spectrometry including the differences between the array of ionization modalities and detectors available today. While mass spectrometry has contributed significantly to drug discovery, recent advances are enabling high-throughput screening applications. Instructors: Jonathan Wingfield, AstraZeneca, Discovery Sciences; Ian Sinclair, AstraZeneca, Discovery Sciences

Gene Editing for Drug Discovery

Genome editing tools such as CRISPR-Cas9 are reshaping what is possible within the biological sciences. This course introduces the possibilities of what can be achieved with genome editing, the current limitations, and the fundamentals of how to apply these technologies to enhance the pursuit of targets and therapeutics. Instructors: John G. Doench, The Broad Institute of MIT and Harvard; Samuel A. Hasson, Pfizer Inc.

TWO-DAY SHORT COURSE: Saturday-Sunday | February 4-5 | 8:30 am - 4:30 pm Getting Started With Excel and VBA in the Laboratory (Laptop Required)

Excel is widely used in scientific laboratories to automate tedious data manipulation and presentation tasks. This course reviews many of the tools built-in to Excel for handling problems commonly encountered in the laboratory. It introduces the Visual Basic for Applications scripting language as a way to customize Excel and expand upon its functionality. Instructors: William Neil; Martin Echols, EcholsTech

SLAS2017.ORG #SLAS2017

11


Conference-At-A-Glance

Short Course Program is held on Saturday, February 4 and Sunday, February 5. For complete listing see pages 8-11.

(SCHEDULE SUBJECT TO CHANGE) Saturday | February 4, 2017 7:30 am - 4:30 pm

Registration Open

8:30 am - 4:30 pm

Short Courses: 3D Cell-Based Assays for Drug De-Risking; Digital Image Processing and Analysis for the Laboratory Scientist: Theory and Application (Laptop Required); Introduction to Laboratory Automation; Lab-on-a-Chip: From Technology to Bioanalysis on Chip Two-Day Course: Getting Started With Excel & VBA in the Laboratory (Laptop Required)

8:30 am - 5:30 pm

Assay Guidance Workshop for High-Throughput Screening and Lead Discovery (Additional fee required.)

Sunday | February 5, 2017 7:30 am - 4:30 pm

Registration Open

8:30 am - 12:00 pm

Half-Day Short Courses: Data Analytic Concepts for High-Throughput Screening & Biomarker Applications (NEW); Introduction to Flow Cytometry (NEW); Lead Generation: A Critical Discussion of Hypothesis & Empirical Strategies

8:30 am - 4:30 pm

Short Courses: Affinity-Based, Biophysical Methods for Screening and Mechanistic Studies: How to Effectively Use a Growing Biophysical Toolbox to Find and Characterize Chemical Leads; Data Management in the Age of Big Data, Mobile and the Cloud; Derivation, Maintenance and Characterization Techniques for Human iPS Cells Used in Drug Discovery and Disease Modeling; Establishing Cell-Based Assays for Screening; High-Content Screening: An Introduction to Instrumentation, Assay Development, Screening, Image and Data Analysis; Liquid Handling Essentials (Interactive Course); Multi Parametric Analysis of High-Content Screening Data (Laptop Required); Next Generation Sequencing Technology Fundamentals and Applications; Pharmacology in Drug Discovery and Development: New Lives for Receptors as Drug Targets Through Allostery and Biased Signaling (NEW); Sample Management: Best Practice, Trends and Challenges Two-Day Course: Getting Started With Excel & VBA in the Laboratory (Laptop Required)

1:00 - 4:30 pm

Half-Day Short Courses: Advanced Flow Cytometry (NEW); An Introduction to Mass Spectrometry and its Applications Within Drug Discovery (NEW); Gene Editing for Drug Discovery

Monday | February 6, 2017 7:00 - 8:00 am 7:30 am - 6:00 pm

Laboratory Products Association (LPA) Special Session Registration Open

8:00 - 8:30 am

Morning Beverage Break

8:30 - 9:00 am

Keynote Session: Welcome and Opening Remarks Sponsored by:

9:00 - 10:00 am

Keynote Speaker: Jennifer Lippincott-Schwartz; Section Chief of the Cell Biology and Metabolism Branch, NICHD, NIH and NIH Distinguished Investigator

10:00 - 10:30 am

Beverage Break in the Exhibition

10:00 am - 1:00 pm

Career Connections: Mentoring Sessions / One-on-One Career Counseling Sessions / Job Boards

10:00 am - 6:00 pm

Exhibition Open

10:00 am - 6:00 pm

Poster Viewing in the Exhibition

10:00 am - 6:00 pm

SLAS Member Center Open in the Exhibition Advances in Bioanalytics, Biomarkers and Diagnostics

10:30 am - 12:30 pm

Label-Free Bioanalytical Techniques for Hit Identification and Optimisation SESSION CHAIR: Melanie Leveridge, GlaxoSmithKline

12:30 - 1:15 pm

Assay Development and Screening

Automation and High-Throughput Technologies

Phenotypic and High Content Screening Assays

Screening Automation: Modular vs. Highly Integrated Systems

SESSION CHAIR: Susanne Heynen-Genel, Sanford Burnham Prebys Medical Discovery Institute

SESSION CHAIR: Paul Anderson, The Genomics Institute of the Novartis Research Foundation

Cellular Technologies

Advances in Genome Editing Technologies SESSION CHAIR: Gregory Davis, MilliporeSigma

Data Analysis and Informatics

Micro- and Nano Technologies

Let There Be Light: Informatics Approaches to Exploring the Dark Genome

Digital and Droplet Microfluidics

SESSION CHAIR: Rajarshi Guha, National Center for Advancing Translational Sciences, National Institutes of Health

SESSION CHAIR: Adam Abate, University of California, San Francisco

Exhibitor Tutorial: BMG LABTECH; Titian Software

SLAS2017.ORG #SLAS2017

12


Monday | February 6, 2017 (continued) 12:30 - 1:30 pm

Lunch in the Exhibition

12:30 - 1:45 pm

Exhibitor Tutorials: Biosero Inc.; Labcyte Inc.; Thermo Fisher Scientific

12:30 - 2:30 pm

Exhibitor Tutorials: Beckman Coulter; PerkinElmer

1:00 - 1:30 pm

SLAS Author Services Info Session in the SLAS Member Center: Meet SLAS Technology Editor-in-Chief Edward Kai-Hua Chow, National University of Singapore

1:00 - 2:00 pm

Career Connections: Mentoring 101 for Scientists Part I — Finding Mentors and Being the Best Mentee You Can Be; Joanne Kamens, Addgene

1:00 - 3:00 pm

Poster Presentations (Odd-Numbered Posters)

1:30 - 2:00 pm

SLAS Author Services Info Session in the SLAS Member Center: Using Kudos to Get More People to Read and Cite Your Research

2:00 - 2:30 pm

SLAS Author Services Info Session in the SLAS Member Center: Accelerate Life Sciences Research with Atypon Literatum

2:00 - 2:45 pm

Exhibitor Tutorials: Genedata; Multispan, Inc.; Thermo Fisher Scientific

2:00 - 5:00 pm

Career Connections: Mentoring Sessions / One-on-One Career Counseling Sessions / Job Boards

2:30 - 3:00 pm

Beverage Break in the the Exhibition Advances in Bioanalytics, Biomarkers and Diagnostics Targeted Biomarker Analysis

3:00 - 5:00 pm

SESSION CHAIR: Dieter Drexler, Bristol-Myers Squibb

Assay Development and Screening

Automation and High-Throughput Technologies

Biochemical and Biophysical Screening

High Content and High-Throughput Automation

SESSION CHAIR: Razvan Nutiu, Novartis Institutes for Biomedical Research

SESSION CHAIR: Louis Scampavia, The Scripps Research Institute

Cellular Technologies

Data Analysis and Informatics

Micro- and Nano Technologies

Development of Cellular Models for Phenotypic Screening

The Challenges and Benefits of Collaboration

Perspectives on Commercialization of Integrated Micro and Nanofluidic Devices

SESSION CHAIR: Joel Klappenbach, Merck & Co., Inc.

SESSION CHAIR: Farida Kopti, Merck & Co., Inc.

SESSION CHAIR: Sammy Datwani, Labcyte Inc.

5:00 - 5:15 pm

Student Poster Award Winner Announcement

5:00 - 5:30 pm

The Lab Man Podcast: SLAS Technology Editor-in-Chief Edward Kai-Hua Chow and SLAS Discovery Editor-in-Chief Robert Campbell: SLAS Journal Name Changes

5:00 - 6:00 pm

The Lab Man Podcast: Student Poster Competition Winners

5:00 - 6:00 pm

Reception in Exhibition: Celebrating the 2017 SLAS Journal Achievement Award Honorees

5:00 - 6:00 pm

Student and Early Career Professionals Mixer in the SLAS Member Center

6:00 - 8:00 pm

Late Night with LRIG - Rapid-Fire Innovation Session

6:30 - 8:30 pm

SLAS Student and Early Career Professionals Networking Event at Lucky Strike

Tuesday | February 7, 2017 6:30 am start

2017 SLAS FUNd Run Sponsored by:

7:15 - 9:00 am

Analytical, Life Science and Diagnostic Association Special Session (ALDA) (Invitation Only)

7:30 - 8:30 am

Career Connections: Grants Process and Funding Opportunities from the National Institutes of Health (NIH); Daniel Gossett, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

7:30 am - 6:00 pm

Registration Open

7:45 - 8:00 am

Morning Beverage Break

8:00 - 9:15 am

Special Interest Group (SIG) Sessions: HCS/HCA Data and Informatics; Technology Transfer and CRO/CMO Project Management; Screen Design and Assay Technology; Sample Management; Stem Cells and 3D Microtissues

9:30 - 10:15 am

Exhibitor Tutorials: Genedata

9:30 am - 12:30 pm

Career Connections: Mentoring Sessions / One-on-One Career Counseling Sessions / Job Boards

9:30 am - 6:00 pm

Exhibition Open

9:30 am - 6:00 pm

Poster Viewing in the Exhibition

9:30 am - 6:00 pm

SLAS Member Center Open in the Exhibition

10:00 - 10:30 am

Beverage Break in the Exhibition

SLAS2017.ORG #SLAS2017

13


Tuesday | February 7, 2017 (continued) 10:00 - 10:30 am

The Lab Man Podcast: How to Get More People to Read and Cite Your Research with Kudos and ORCID Advances in Bioanalytics, Biomarkers and Diagnostics

10:30 am - 12:30 pm

Target Identification After Phenotypic Screening SESSION CHAIR: Shaun McLoughlin, AbbVie Laboratories

Assay Development and Screening

Assay Platforms for Biologics SESSION CHAIR: Rob Howes, Medlmmune

Automation and High-Throughput Technologies Automating Phenotypic and Target Based Discovery Using Parallel Automated Approaches SESSION CHAIR: Robin Felder, The University of Virginia

Cellular Technologies

Data Analysis and Informatics

Enhancing Scientific Genetic Screens for Reproducibility Target Discovery and Reuse and Validation Through Better Workflow and Data SESSION CHAIR: Technologies Louis Staudt, National Cancer SESSION CHAIR: Institute Timothy Gardner, Riffyn

Micro- and Nano Technologies

Single Cell Analyses SESSION CHAIR: Daniel Chiu, University of Washington

12:30 - 1:15 pm

Exhibitor Tutorials: Agilent Technologies Inc.; Artel; Biodesy, Inc.; BMG LABTECH; Festo Corporation; Transcriptic

12:30 - 1:30 pm

Lunch in the Exhibition

12:30 - 1:45 pm

Exhibitor Tutorials: IntelliCyt; Labcyte Inc.

12:30 - 2:30 pm

Exhibitor Tutorial: PerkinElmer

1:00 - 1:30 pm

SLAS Author Services Info Session in the SLAS Member Center: Meet SLAS Discovery Editor-in-Chief Robert Campbell, Eli Lilly and Company

1:00 - 2:00 pm

Career Connections: Mentoring 101 for Scientists Part II — Best Practices for the Mentor (And Anyone Can Be One!); Joanne Kamens, Addgene

1:00 - 3:00 pm

Poster Presentation (Even-Numbered Posters)

1:30 - 2:00 pm

SLAS Author Services Info Session in the SLAS Member Center: Distinguish Yourself in the Literature with ORCID

2:00 - 2:30 pm

SLAS Author Services Info Session in the SLAS Member Center: Social Media Strategies for Journal Authors

2:00 - 2:45 pm

Exhibitor Tutorial: TTP Labtech

2:00 - 5:00 pm

Career Connections: Mentoring Sessions / One-on-One Career Counseling Sessions / Job Boards

2:30 - 3:00 pm

Beverage Break in the Exhibition Assay Development and Screening

Rational Screen Design 3:00 - 5:00 pm

SESSION CHAIR: Edward Ainscow, Carrick Terapeutics

Automation and High-Throughput Technologies

Data Analysis and Informatics

Using Making Scientific PhysiologicallyData 100x Easier Relevant Models for to Use Automated Screens SESSION CHAIR: SESSION CHAIR: Megean Shane Homan, The Schoenberg, Genomics Institute Merck Research of the Novartis Labs Research Foundation

Drug Target Strategies

Micro- and Nano Technologies

Hard Targets: Success Through Collaborations

Making MicroVolume Biology Work: Tools, Techniques & Secrets

SESSION CHAIR: Chun-Wa Chung, GlaxoSmithKline

Special Session Whose Responsibility is Research Reproducibility?

SESSION CHAIRS: Lenny Teytelman, SESSION CHAIR: Protocols.io; Dan Sipes, The Cathy TralauGenomics Institute Stewart, University of the Novartis of California, Research Foundation San Francisco

5:00 - 5:30 pm

The Lab Man Podcast: SLAS Technology Editor-in-Chief Edward Kai-Hua Chow and SLAS Discovery Editor-in-Chief Robert Campbell: SLAS Journal Name Changes

5:00 - 6:00 pm

Reception in the Exhibition

6:30 - 9:30 pm

Tuesday Evening Celebration – Newseum Sponsored by:

Wednesday | February 8, 2017 7:30 - 8:30 am

Career Connections: Surviving a Non-Academic Interview: What to Say, and When; Colin White, White Consulting

7:45 - 8:00 am

Morning Beverage Break

8:00 - 9:15 am

SLAS Author Workshop: How to Prepare a Manuscript for Publication

8:00 - 9:15 am

Special Interest Group (SIG) Sessions: Labware Leachables; Phenotypic Drug Discovery; Women Professionals in Science and Technology; Compound Combination; Ultra-High-Throughput Screening

SLAS2017.ORG #SLAS2017

14


Wednesday | February 8, 2017 (continued) 8:30 am - 1:30 pm 9:00 - 9:30 am

Registration Open Morning Beverage Break

9:00 am - 1:00 pm

Exhibition Open

9:00 am - 1:00 pm

SLAS Member Center Open in the Exhibition

9:15 - 9:30 am

New Product Award Announcement Assay Development and Screening

Screening the Undruggable 9:30 - 11:30 am

10:00 - 11:00 am

SESSION CHAIR: John Lazo, The University of Virginia

Automation and High-Throughput Technologies Automating Novel Analytical Tools for PKA, Drug-Drug Combination and Synergy Assays, Drug Repurposing SESSION CHAIR: Wei Zheng, National Center for Advancing Translational Sciences, National Institutes of Health

Data Analysis and Informatics

Drug Target Strategies

Informatics of Uniting Phenotypic Drug Design and and Target-Based Compound Life Drug Discovery Cycle Management SESSION CHAIR: SESSION CHAIR: Fabien Vincent, Dmitry Lupyan, Pfizer Inc. Schrodinger

Micro- and Nano Technologies

Bioprinting: Multidimensional Microscale Cellular/ Tissue Engineering SESSION CHAIR: Markus Rimann, Zurich University of Applied Sciences

Special Session Regenerative Medicine: Next Generation Treatments SESSION CHAIRS: Marcie Glicksman, ORIG3N; G. Sitta Sittampalam, National Center for Advancing Translational Sciences, National Institutes of Health

The Lab Man Podcast: New Product Award Winners

11:30 am - 12:00 pm

Lunch in the Exhibition

11:45 am - 12:00 pm

Passport to Prizes Award Announcements in the Exhibition

12:00 - 12:45 pm

Exhibitor Tutorials

12:00 - 1:15 pm

Special Interest Group (SIG) Sessions: Academic Drug Discovery; ADMET; Automation Quality Control; Standards Initiatives; Automated Sample Preparation of Pharmaceutical Dosage Forms; Drug Repurposing Cellular Technologies Cellular Manipulation and Genome Editing in Screening Assay Design

1:30 - 3:30 pm

SESSION CHAIR: Ralph Garippa, Memorial SloanKettering Cancer Center

Automation and High-Throughput Technologies

Data Analysis and Informatics

In-House Automation: Devices and Software Developed Internally

The Digital Dark Hole: Handling Large-Scale Data for Use, Reuse, and Sharing

SESSION CHAIR: Rob Keyser, Calico Life Sciences

SESSION CHAIR: Laurie Goodman, GigaScience

Drug Target Strategies

Micro- and Nano Technologies

Non-Traditional Modalities as Therapeutics

Microphysiological Systems

SESSION CHAIR: Stephen Hale, Ensemble Therapeutics

SESSION CHAIR: Daniel Huh, University of Pennsylvania

3:30 - 3:45 pm

Beverage Break

3:45 - 5:00 pm

Keynote Session and Innovation Award Announcement: Rachel Swaby, Author of Headstrong: 52 Women Who Changed Science—and the World. Keynote sponsored by:

5:00 - 5:30 pm

Book Signing with SLAS Closing Keynote, Rachel Swaby

JOIN THE SLAS SOCIAL MEDIA COMMUNITIES #SLAS2017

SLAS2017.ORG #SLAS2017

Our online communities are growing every day. Stay up-to-date and join in the discussions. Sign-up now!

15


Networking

A hallmark of the SLAS experience is intelligent network building. SLAS is a global community, and participants consistently cite the friendliness, cooperation and open spirit of collaboration as a reason they return to this conference year after year. Networking activities at SLAS2017 include daily meals and receptions in the exhibit area, evening functions, a fun run with fellow attendees, Special Interest Groups (SIGs), special programming for students, early career professionals and international guests, and much more. See details on SLAS2017.org.

Evening Celebration at the Newseum

Tuesday | February 7 | 6:30-9:30 pm

A renowned attraction of the U.S. capital city, the Newseum has welcomed more than six million guests since it opened in its current location in 2008. The Newseum promotes, explains and defends free expression and the five freedoms of the First Amendment of the U.S. Constitution: religion, speech, press, assembly and petition. On the evening of Tuesday, February 7, SLAS2017 attendees enjoy three hours of exclusive access to this world-class cultural institution, featuring seven stories of interactive exhibits, 15 galleries and 15 theatres. Complimentary transportation, food, drink and museum access is provided.

Sponsored by:

SLAS2017.ORG #SLAS2017

16


SLAS Member Center

The SLAS Member Center is THE place for members – and non-members – to learn everything there is to know about the many year-round benefits and services available through SLAS. Conveniently located in the SLAS2017 Exhibition, the Member Center is central hub for SLAS information and activity, including:

CAREER SERVICES

Take advantage of FREE career services, see page 20 for additional details.

LIVE PODCASTS WITH THE LAB MAN Monday | February 6 5:00 pm – Student Poster Competition Winners

Tuesday | February 7 10:00 am – How to Get More People to Read and Cite Your Research with Kudos and ORCID 5:00 pm – SLAS Technology Editor-in-Chief Edward Kai-Hua Chow and SLAS Discovery Editor-in-Chief Robert Campbell: SLAS Journal Name Changes

Wednesday | February 8 10:00 am – SLAS New Product Award Designation Winners

AWARD ANNOUNCEMENTS

Student Poster Competition winners, New Product Award winners, and the 2017 SLAS Journal Achievement Award honorees.

MEMBERSHIP

Learn about SLAS’s refreshed membership models, enhanced benefits and how to get the most out of the Society’s year-round programs and services. Plus, discover the new SLAS Fellow Member category and meet members of inaugural class of SLAS Fellows.

PASSPORT TO PRIZES

Play the Passport to Prizes game and you could win fabulous prizes. To play, simply visit some of the many exhibitors participating in the SLAS2017 Exhibition and have your passport card stamped at their booth. Submit your completed passport to the SLAS Member Center and return for the prize drawing on Wednesday, February 8, 11:45 am. (Only those present at the prize drawing will be eligible to win.)

WASHINGTON, DC’S ELITE FIRST ROBOTICS TEAMS

SLAS is proud to partner with FIRST to showcase the amazing ingenuity of the next generation of scientific engineering. Washington, DC’s Elite FIRST teams demonstrate their remarkable robotic inventions in the SLAS2017 Exhibition. Stop by to congratulate these remarkable future engineers. In addition, in the Member Center you can receive a guided tour of SLAS.org, a review of your SLAS member benefits, and some great giveaways. Members of the SLAS leadership and the Society’s professional team are available to answer questions and point out all that SLAS has to offer to benefit you not only at SLAS2017, but year-round.

SLAS2017.ORG #SLAS2017

17


SLAS Scientific Journals at SLAS2017 SLAS publishes two rigorously peer-reviewed MEDLINE-indexed scientific journals — SLAS Discovery (Advancing Life Sciences R&D) and SLAS Technology (Translating Life Sciences Innovation). Visit the journals’ station in the SLAS Member Center to meet the publishing team, learn more about the journals’ editorial scope and find out how to: ■■ Search,

secure and manage information via SLAS Discovery Online and SLAS Technology Online.

■■ Submit

an original scientific manuscript to SLAS Discovery or SLAS Technology.

■■ Increase

awareness, discoverability and citations of your published manuscripts.

■■ Sign

up for 30 days FREE ACCESS to SLAS Discovery and SLAS Technology.

■■ Pick

up sample copies of SLAS Discovery and SLAS Technology (while supplies last).

SCHEDULE OF AUTHOR SERVICES INFORMATION SESSIONS Monday | February 6

Tuesday | February 7

1:00 - 1:30 pm Meet SLAS Technology Editor-in-Chief Edward Kai-Hua Chow, National University of Singapore 1:30 - 2:00 pm Using Kudos to Get More People to Read and Cite Your Research 2:00 - 2:30 pm Accelerate Life Sciences Research with Atypon

1:00 - 1:30 pm Meet SLAS Discovery Editor-in-Chief Robert Campbell, Eli Lilly and Company 1:30 - 2:00 pm Distinguish Yourself in the Literature with ORCID 2:00 - 2:30 pm Social Media Strategies for Journal Authors

Wednesday | February 8 8:00 - 9:15 am

SLAS Author Workshop: How to Prepare a Manuscript for Publication

SLAS Technology Editor-in-Chief Edward Kai-Hua Chow, National University of Singapore

SLAS Discovery Editor-in-Chief Robert M. Campbell, Eli Lilly & Co.

Join the editors-in-chief of the SLAS journals for a step-by-step overview of how to design and write scientific research papers more clearly and effectively to improve their chances for publication. Attendees learn what editors want, what they don’t want, common mistakes, insider tips and how reviewers evaluate manuscripts. Presented by SLAS Discovery Editor-in-Chief Robert M. Campbell, Eli Lilly & Co. and SLAS Technology Editor-in-Chief Edward Kai-Hua Chow, National University of Singapore.

  SLAS2017.ORG #SLAS2017

18


SLAS Special Interest Groups (SIGs) ■■ Academic

Drug Discovery

SLAS SIGs allow you to connect directly with peers who share similar interests and expertise in specific scientific technology disciplines. SIGs are a great way to discuss leading-edge trends, meet recognized experts and collaborate with peers. SIGs scheduled to meet at SLAS2017 appear below. For descriptions and a meeting schedule, visit SLAS2017.org. ■■ Sample

Management

■■ ADMET

■■ Screen

■■ Automated

■■ Standards

Sample Preparation of Pharmaceutical Dosage Forms

■■ Automation ■■ Drug

Quality Control

Repurposing

■■ HCS/HCA ■■ Labware

Data and Informatics

Leachables

■■ Phenotypic

Celebrate Excellence

Drug Discovery

■■ Stem

Design and Assay Technology Initiatives

Cells and 3D Microtissues

■■ Technology

Transfer and CRO/CMO Project Management

■■ Ultra-High-Throughput

for SLAS2017)

Screening (NEW

■■ Women

Professionals in Science and Technology

The Society’s highest honors recognize significant contributions to the field of life sciences discovery and technology by SLAS members, students, conference participants and companies.

$10,000 SLAS Innovation Award

This $10,000 cash prize award recognizes the work behind one SLAS2017 scientific podium presentation that is exceedingly innovative and contributes to the exploration of technologies in the laboratory. Last year’s winner was Shana Kelley, University of Toronto (Canada), for her award winning presentation: New Devices for the Detection and Classification of Antibiotic-Resistant Bacteria. The Innovation Award winner is announced during the closing session of SLAS2017 on Wednesday afternoon, February 8.

Tony B. Academic Travel Awards

The Tony B. Academic Travel Award Program recognizes up-and-coming researchers who demonstrate outstanding achievement in laboratory science and technology. The Tony B. Academic Travel Awards include round trip coach airfare, conference registration and hotel accommodations. Each scholarship recipient actively participates in the conference by presenting a podium presentation or a poster. See a listing of award recipients participating at SLAS2017 on SLAS2017.org.

Student Poster Competition

$500 cash awards are presented to the top three student poster winners at SLAS2017. The winning posters are showcased in the SLAS Member Center and on SLAS2017.org. Additionally, the winners are interviewed by The Lab Man for his blog and podcast. The poster award ceremony takes place Monday, February 6, 5:00 pm.

SLAS2017.ORG #SLAS2017

19


Career Connections

SLAS2017 delivers a host of unique resources to help you accelerate your career and distinguish yourself in a competitive profession.

CAREER MENTORING

Several experienced professionals, including members of ACS Washington, DC Chapter, will be on hand to provide complimentary mentoring and career advice. Advance sign-up is required and offered through SLAS2017.org.

CAREER-FOCUSED PROGRAMMING

Students and Early Career Professionals can take part in SLAS Career Connections at SLAS2017. Career Connections is one of the select few, highly discreet, automated employment programs that brings together its online professional services with its respected career center and development sessions at SLAS2017. Expert-led career workshops offered at SLAS2017 in Washington, DC, include:

DANIEL GOSSETT

JOANNE KAMENS

Program Director, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Addgene

Monday | February 6 | 1:00 - 2:00 pm Mentoring 101 for Scientists Part I — Finding Mentors and Being the Best Mentee You Can Be

Tuesday | February 7 | 1:00 - 2:00 pm Mentoring 101 for Scientists Part II — Best Practices for the Mentor (and Anyone Can Be One!) These workshops give practical advice about finding, utilizing and being a mentor in a fun, interactive format.

Tuesday | February 7 | 7:30 - 8:30 am Grants Process and Funding Opportunities from the National Institutes of Health (NIH) This presentation will provide an overview of the NIH grants process, grant writing, and funding opportunities spanning research training and career development to research project grants (R01s) to small business grants (SBIR & STTR).

COLIN WHITE

White Consulting

Wednesday | February 8 | 7:30 - 8:30 am Surviving a Non-Academic Interview: What to Say, and When This session covers all aspects of an interview, from analyzing the questions being asked through directing the conversation towards where you feel most comfortable. Other topics include techniques to alleviate stress before the interview, how to maximize the time available to learn more about the organization, and follow upappropriately.

SLAS AUTHOR WORKSHOP: HOW TO PREPARE A MANUSCRIPT FOR PUBLICATION Wednesday | February 8 | 8:00 - 9:15 am

Join the editors-in-chief of the SLAS journals for a step-by-step overview of how to design and write scientific research papers more clearly and effectively to improve their chances for publication. See page 18 for more details.

SLAS2017.ORG #SLAS2017

20


The Exhibition

The SLAS2017 Exhibition is an all-in-one venue to see the latest scientific technologies and to visit with product experts and developers from more than 300 leading multinational providers. From robotics to reagents, the SLAS2017 Exhibition presents a unique opportunity to see the latest scientific technologies “in action” as well as to speak directly to product developers and experts about your specific environment – and the tools available to reach your objectives.

The SLAS2017 Exhibition includes: ■■

State-of-the-art exhibits that showcase the latest scientific technologies in functional lab settings

■■

Exhibitor-led tutorials that complement your technical education experience

■■

Innovation AveNEW, a dedicated area of the floor that hosts a select group of emerging companies offering high-potential new technologies

■■

The SLAS2017 Scientific Poster Gallery, including opportunities to interact with poster authors

■■

The SLAS New Product Award (NPA) that recognizes up to three new products being showcased in the SLAS2017 Exhibition

Visit SLAS2017.org for the latest list of exhibiting companies, company descriptions, an exhibition floorplan and a schedule of events in the SLAS2017 Exhibition.

SLAS2017 EXHIBITION HOURS Monday | February 6 | 10:00 am - 6:00 pm (Reception 5:00 - 6:00 pm) Tuesday | February 7 | 9:30 am - 6:00 pm (Reception 5:00 - 6:00 pm) Wednesday | February 8 | 9:00 am - 1:00 pm SLAS2017 Exhibition only registration is available free-of-charge. Register at SLAS2017.org.

Exhibitor Tutorials

LEARN ABOUT THE SCIENCE BEHIND THE TECHNOLOGY

As of press time, the following companies are presenting tutorials that offer an in-depth look at topics of ongoing practical interest. Visit SLAS2017.org for the latest list of participating companies and schedule of tutorials.

Monday | February 6

Tuesday | February 7

12:30 - 1:15 pm BMG LABTECH Titian Software

12:30 - 2:30 pm Beckman Coulter PerkinElmer

12:30 - 1:45 pm Biosero Inc. Labcyte Inc. Thermo Fisher Scientific

2:00 - 2:45 pm Genedata Multispan, Inc. Thermo Fisher Scientific

SLAS2017.ORG #SLAS2017

9:30 - 10:15 am Genedata 12:30 - 1:15 pm Agilent Technologies Inc. Artel Biodesy, Inc. BMG LABTECH Festo Corporation Transcriptic

12:30 - 1:45 pm IntelliCyt Labcyte Inc. 12:30 - 2:30 pm PerkinElmer 2:00 - 2:45 pm TTP Labtech

21


SLAS2017

Exhibitor Listing

For additional information on participating companies and to access the exhibition map, VIEW HERE

4titude Ltd

BioMicroLab, Inc.

Cosmo Biotechnologies LTD

Abcam

Bioneer Inc.

Covaris, Inc.

ABS Inc.

BioNex Solutions, Inc.

CryoXtract Instruments

Accel Biotech, Inc.

BioreclamationIVT

CSEM

ACEA Biosciences, Inc.

BioSero, Inc.

DDNews

Advanced Analytical

BioTek Instruments, Inc.

Digilab, Inc.

Agilent Technologies Inc.

Biotix, Inc.

DiscoveRx Corporation

AllMotion

Black Dog Technical Services, Inc.

Douglas Scientific

BlueCatBio

Drug Discovery World

Alpaqua Engineering LLC AMRI amsbio LLC Analytical Sales and Services, Inc. Analytik Jena US, Inc. AnaSpec, EGT Group Andrew Alliance Apricot Designs Arc-Tronics Inc.

BMG Labtech, Inc. Brady Corporation BrandTech Scientific, Inc. Brookline Scientific Ltd Brooks Automation Bruker Corporation Burkert Fluid Control Systems

Artel

Cellular Dynamics International, a Fujifilm Company

Astech Projects Ltd.

ChemBridge Corporation

Atlantic Lab Equipment, Inc.

Chemspeed Technologies, Inc.

Art Robbins Instruments

AUTOMATOR AMERICA INC.

Chieftek Precision Co., Ltd.

Axion Biosystems, Inc.

Cisbio Bioassays

Bangs Laboratories, Inc.

Click Bio

Beckman Coulter, Inc.

Clippard Instrument Lab., Inc.

BellBrook Labs Benchmark Electronics BERTHOLD TECHNOLOGIES GmbH & Co. KG

Clontech Laboratories, Inc. Cognex Corporation Collaborative Drug Discovery

Draper Dynamic Biosensors GmbH Dynamic Devices E&K Scientific Products Inc. emp Biotech Eppendorf EPSON Robots EQUIcon Software Excel Scientific, Inc. Exquiron Biotech AG Festo Corporation Fluotics, Ltd Formulatrix, Inc. Fraunhofer ICT-IMM Frontier Scientific Services GA International Gene Era Biotech

Helix Linear Technologies, Inc. Hettich HighRes Biosolutions HIWIN Corporation HMS Industrial Networks HNP Mikrosysteme GmbH HORIBA Scientific Horizon Discovery Ltd Hudson Robotics, Inc. Icagen, Inc. IDEA Bio-Medical Ltd IDEX Health & Science Igus, Inc IKA Works, Inc. IKO International, Inc. infoteam Software AG INHECO GmbH Innoprot Innova Biosciences Innovation AveNEW InSphero, Inc. INTEGRA Biosciences IntelliCyt Corporation IonField Systems LLC J-Kem Scientific

Genedata

Key Tech

Genetic Engineering & Biotechnology News

KMC Systems, Inc. KNF Neuberger Inc.

Gilson, Inc.

Kuraray, Co. Ltd

GNF Systems

Lab Services B.V. Labcon

Bigneat LLC

Computype

Greiner Bio-One

Biodesy

Confluence Discovery Technologies

Grenova LLC

Labcyte Inc.

Hamamatsu Corporation

LabMinds Ltd

BioDot, Inc.

Cooperative Human Tissue Network (CHTN)

Hamilton Company

LabRepCo

BioMedTech Laboratories, Inc.

Corning Life Sciences

HD Biosciences Co, Ltd

LABVANTAGE Solutions, Inc.

Biodirect Inc.

SLAS2017.ORG #SLAS2017

LabWare, Inc.

22


SLAS2017

Exhibitor Listing CONTINUED

For additional information on participating companies and to access the exhibition map, VIEW HERE

LabX Media Group

Nanion Technologies

PureHoney Technologies

Solid State Cooling Systems

Lathrop Engineering Inc.

Nanomedical Diagnostics

Sparton

LEAP Technologies

NanoTemper Technologies, Inc.

Quantifoil Instruments GmbH Reaction Biology Corp

SPEX SamplePrep LLC

The Lee Company LiCONiC Lin Engineering, Inc. Lonza Inc. Lumigen, a Beckman Coulter Company

New England Small Tube Corporation

regenHU Ltd

Nexcelom Bioscience

Retisoft, Inc.

Nippon Pulse Norgren, Inc.

LVL technologies GmbH & Co. KG

Nova Biostorage Plus, LLC

Macherey-Nagel, Inc.

Omni International, Inc.

MeCour Temperature Control

OMS Motion, Pro-Dex

Meso Scale Discovery

Opticon

microdrop Technologies GmbH microfluidic ChipShop GmbH MICROMO Micronic America Micronit Microfluidics BV Microscan Microsonic Systems Inc. MilliporeSigma Miltenyi Biotec GmbH MIMETAS BV MiniFab Minitubes MK Fluidic Systems, LLC Moeller Medical GmbH Molecular Devices Multispan, Inc.

SLAS2017.ORG #SLAS2017

Omega Bio-Tek, Inc.

ONExia, Inc. Oriental Motor USA Corp. Pall Life Sciences

Renishaw Inc. Rithum Automation LLC RURO, Inc. Russell Publishing SAMDI Tech, Inc. Sarstedt, Inc. Sartorius S-BIO, SUMITOMO Bakelite Co., Ltd Schneider Electric Motion USA

Specs Tecan Technology Networks Ltd Tecnisco, Ltd Tek-Matic, Inc. Thermo Fisher Scientific Titian Software Torrey Pines Scientific, Inc. Transcriptic Trinean TTP Labtech TubeWriter TWD TradeWinds, Inc.

SCIENION US, Inc.

Unchained Labs Union Biometrica, Inc.

Parker Hannifin

Scientific Device Laboratory, Inc.

Peak Analysis and Automation

Scigilian Software, Inc. Scinomix, Inc.

V&P Scientific, Inc.

PerkinElmer

SCIVAX Life Sciences, Inc.

Phenix Research

Seahorse Microplates, A part of Agilent Technologies

Panasonic Industrial Devices Sales Company of America

Photometrics Phytronix Technologies Inc. Pivot Park Screening Centre Plastic Design Corporation Precise Automation

Selleck Chemicals LLC Seyonic SA Singer Instruments SiO2 Medical Products

USA Scientific, Inc. Valcor Engineering VICI Valco Instruments Volpi Manufacturing Wagner Life Science Weidmann Medical Technology AG Wheaton Wiley

Precision for Medicine

Sirius Automation

Precision System Science

SLAS

Zaber Technologies

Prince Technologies B.V.

SMC Corporation of America

ZenBio, Inc.

Promega

Xavo Systems AG

23


Registration and Hotel Accommodations REGISTRATION

SLAS2017 is pleased to offer significant registration discounts to advance registrants, for groups of registrants from the same industry organization, for professionals from academic institutions and government agencies, and for students. Deepest early-bird discounts are available for SLAS members who register by October 31, 2016. (Become an SLAS member to take advantage of these discounts, plus receive year-round member benefits through the end of 2017.) Advance registration discounts are available through December 19, 2016. SLAS is pleased to offer group discounts on SLAS2017 registration for groups registering individuals in increments of five (5) registrants from the same company. Student registrants are not eligible for SLAS2017 group discounts. See terms and conditions for Group Registration discounts at SLAS2017.org.

HOTEL ACCOMMODATIONS

SLAS has negotiated discounted rates at two of DC’s premier conference hotels: Marriott Marquis Washington, DC and the Renaissance Washington, DC Downtown. The Marriott Marquis Washington, DC, the official SLAS2017 headquarters hotel, is the closest to the SLAS meeting space within the convention center and is connected to it via an indoor underground walkway. See complete details and access the unique SLAS attendee reservation link on SLAS2017.org. Booking a room at one of these properties using official SLAS reservation methods will ensure you receive the exclusive SLAS attendee discount rate, plus other benefits and safeguards, including complimentary guest room internet access. See complete information and access the unique SLAS attendee reservation link on SLAS2017.org.

Marriott Marquis Washington, DC (Headquarters Hotel) 901 Massachusetts Avenue NW Washington, DC 20001 n Standard

Nightly Rate: $265 + state and local tax n Complimentary Guest Room Internet n Complimentary Guest Access to Hotel Fitness Center

Renaissance Washington, DC Downtown 999 Ninth Street NW Washington, DC 20001 n Standard

Nightly Rate: $260 + state and local tax n Complimentary Guest Room Internet n Complimentary Guest Access to Hotel Fitness Center

To reserve your room online using official SLAS2017 channels, visit the Hotel and Travel page of SLAS2017.org. The deadline for booking hotel accommodations at the negotiated SLAS2017 rate is January 5, 2017. Bookings made after this date will receive the discounted rate based only on individual hotel availability.

SLAS2017.ORG #SLAS2017

24


Travel Information AIR TRAVEL

You may book your air travel directly with SLAS2017’s official travel agent, National Travel at: vipservices@nationaltravel.com; +1.800.557.0842 (toll free); +1.304.357.0808 (international) There are three international airports serving the Washington, DC area: ■■ Reagan ■■ Dulles

National Airport (DCA)

International Airport (IAD)

■■ Baltimore-Washington

Marshall Airport (BWI)

International Thurgood

AIRPORT TRANSPORTATION From Reagan National Airport (DCA)

Reagan National Airport is the closest airport to the convention center and official SLAS2017 hotels and is also the only airport with direct Metro access.

AMTRAK

Union Station in Washington, DC is approximately

1.3 miles from the Walter E. Washington Convention Center and official hotels. Metrorail Stop: Red line toward Shady Grove/ Grosvenor; Change trains at Gallery Place then Yellow line to Mt Vernon stop Taxi Cab: Approximately 5 minutes (w/o traffic); approximately $8 one-way

RENTAL CAR

National Travel can also assist you in adding a

rental car to your existing reservation or in booking a rental car as a stand-alone reservation: vipservices@ nationaltravel.com; +1.800.557.0842 (toll free); +1.304.357.0808 (international)

Metrorail Stop: Yellow line to Mt Vernon stop Taxi Cab: Approximately 20 minutes (w/o traffic); approximately $45 one way

From Baltimore/Washington International Thurgood Marshall Airport (BWI)

Taxi Cab: Approximately 60 minutes (w/o traffic); approximately $90 one-way

From Dulles International Airport (IAD)

Taxi Cab: Approximately 45 minutes (w/o traffic); approximately $64 one-way

THE BENEFIT OF STAYING IN THE OFFICIAL SLAS2017 HOTELS SLAS2017 has negotiated special rates and benefits for conference attendees at two of Washington, DC’s premier convention center hotels: Marriott Marquis Washington, DC and the Renaissance Washington, DC Downtown. Not only are these hotels conveniently located adjacent to the convention center, but SLAS2017 attendees benefit in several other ways: ■■ Significant

discounts off standard guest room rates ■■ Complimentary guest room Internet service (value of up to $15 per night) ■■ Complimentary guest access to hotel fitness center ■■ Flexible booking policies ■■ Simplified ability to make reservation changes, if required Staying in one of the official SLAS2017 hotels enables SLAS to contract premier facilities such as the Walter E. Washington Convention Center and helps keep registration fees as affordable as possible. Your support of these hotels during SLAS2017 is greatly appreciated.

SLAS2017.ORG #SLAS2017

25


SLAS Board of Directors and Conference Committees SLAS2017 SCIENTIFIC PROGRAM COMMITTEE SLAS2017 Conference Chairs

Marcie Glicksman

Dana Vanderwall

ORIG3N

Bristol-Myers Squibb

MICRO- AND NANOTECHNOLOGIES TRACK

Sindy Tang, Chair Stanford University

Andrew deMello, Associate Chair

Institute for Chemical and Bioengineering ADVANCES IN BIOANALYTICS, BIOMARKERS AND DIAGNOSTICS TRACK

CELLULAR TECHNOLOGIES TRACK

Dieter Drexler, Chair

The Broad Institute

Bristol-Myers Squibb

Melanie Leveridge, Associate Chair GlaxoSmithKline

ASSAY DEVELOPMENT & SCREENING TRACK

Cathy Tralau-Stewart, Chair University of California, San Francisco

Ed Ainscow, Associate Chair Carrick Therapeutics

AUTOMATION AND HIGH-THROUGHPUT TECHNOLOGIES TRACK

Craig Schulz, Chair Amgen

Taosheng Chen, Associate Chair St. Jude Children’s Research Hospital

John Doench, Chair

SLAS SCIENTIFIC PROGRAM ADVISORY COMMITTEE

Benjamin Haley, Associate Chair

Douglas Auld, Chair

DATA ANALYSIS AND INFORMATICS TRACK

Michelle Arkin

Genentech

Lenny Teytelman, Chair

Novartis Institutes for Biomedical Research

University of California, San Francisco

Protocols.io

Dino Di Carlo

Margaret DiFilippo, Associate Chair

Marcie Glicksman

Dotmatics

DRUG TARGET STRATEGIES TRACK

David Swinney, Chair

Institute for Rare and Neglected Diseases Drug Discovery

Chun-wa Chung, Associate Chair

University of California, Los Angeles ORIG3N

Timothy Spicer Scripps

Dana Vanderwall

Bristol-Myers Squibb

Andrea Weston Pfizer Inc.

GlaxoSmithKline

SLAS Board of Directors Richard Eglen

Michele A. Cleary

Ian Shuttler

Scott Atkin

Peter Grandsard

Mike Snowden

Alastair Binnie

Susan M. Lunte

Sabeth Verpoorte

Corning Life Sciences SAGIAN Ventures Bristol-Myers Squibb

SLAS2017.ORG #SLAS2017

Bristol-Myers Squibb Amgen

University of Kansas

Tecan Trading AG AstraZeneca

University of Groningen

26


SLAS2017

Sponsors Premier Sponsor:

DIAMOND

SLAS gratefully thanks Hamilton for underwriting many of this year’s conference activities.

GOLD TM

PLATINUM

SILVER

To reserve your sponsorship or for more information please contact: Mary Michalik, Sponsorship Manager; mmichalik@SLAS.org; +1.312.265.9650 SLAS2017.ORG #SLAS2017

27


SLAS2017

Media Partners

BİYOTEKNOLOJİ & YAŞAM BİLİMLERİ GAZETESİ

SLAS2017.ORG #SLAS2017

28

SLAS2017 Preliminary Program