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, SHORT COURSES: february / seven – eight CONFERENCE:

february / nine – eleven

EXHIBITION:

february / eight – ten

Register by October 31 for deepest discounts

PRELIMINARY PROGRAM SLAS2015.ORG Premier Sponsor:

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TABLE OF CONTENTS

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What’s New

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Short Courses

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Keynotes

9

Alliances

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Government Focus

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Special Sessions

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2015 SLAS Leadership Forum

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Schedule

25

SLAS SIGs

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Awards

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Networking

31

Journal Activities

33

Career Connections

34

Exhibition

36

Registration and Hotel Accommodations

38

Board and Committees

40

Sponsors

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Registration Form


WHAT’S NEW AT SLAS2015

SLAS strives to continually improve the quality of all the Society’s programs. SLAS2015 is no exception. Check out these new and improved aspects on tap for SLAS2015:

WASHINGTON, DC, LOCATION:

NEW SIG - AUTOMATED SAMPLE PREPARATION OF PHARMACEUTICAL DOSAGE FORMS:

SLAS2015 marks the first time SLAS convenes in Washington, DC. In addition to the conveniently accessible location and cultural attractions, DC enables a truly unique roster of high-profile presenters and participants, including NIH Director Francis Collins and NCATS Director Chris Austin. For more details on programming geared specifically towards scientists from government laboratories and agencies, see page 10.

Get in on the ground floor with this new SLAS Special Interest Group dedicated to those interested in the current and future state of automation platforms used in sample preparation of pharmaceutical dosage forms. See pages 25-27 for a list of SLAS2015 SIGs. 2015 SLAS LEADERSHIP FORUM: SLAS will host its first Leadership Forum at SLAS2015. This unique program, tailored to the needs and interests of executive-level professionals, features a distinguished collection of participants and attendees discussing strategic-caliber issues in life science R&D. A highlight of this forum is a panel discussion on “Rescuing US Biomedical Research From Its Systemic Flaws.” See page 12 for details on this inaugural, invite-only program offering.

SPECIAL SESSIONS: Program planners have curated several special sessions, each comprised of multiple presentations. These include European Government/Foundation Drug Discovery Initiatives, An Evening With NIH, and The Commercialization of Laboratory Technologies: From Ideas to Reality (presented by the Journal of Laboratory Automation). See page 11 for additional details on these sessions.

CELEBRATE 20 YEARS OF JOURNAL PUBLISHING:

REVAMPED SHORT COURSES:

2015 marks 20 years of publishing for SLAS’s two peer-reviewed, MEDLINE-indexed scientific journals, JALA and JBS. Join in the festivities with a number of author meetand-greets, instruction on how to improve the quality and discoverability of your own research, and other special programming. See details on page 31.

SLAS2015 features a completely updated lineup of Short Courses, including seven brand new offerings. See pages 4 - 7 for a listing and descriptions of SLAS2015 Short Courses. CAREER CONNECTIONS AND STUDENT PROGRAMMING: A host of career services and educational workshops are offered to help you set or redirect your career trajectory. See details on page 33.

SLAS2015 Conference App Use your smartphone or tablet to stay on top of the latest SLAS2015 news, plan your itinerary, review session abstracts, take notes, visit the e-poster gallery, view a virtual exhibition floor map and exhibitor listing, and more with the SLAS2015 conference app for iOS and Android devices, available as a free download in early 2015. Watch SLAS2015.org for information.

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Sponsored by


SHORT COURSES 17 Short Courses will kick-off SLAS2015 on Saturday-Sunday, February 7-8. This completely revamped lineup is sure to help your research proficiency, increase your understanding of prevalent automation techniques, and improve your value to your organization. SLAS2015 Short Course attendance is limited and requires an additional registration fee. For costs and other details, visit SLAS2015.org.

saturday, february seventh

Liquid Handling Essentials – A Hands-On Workshop Bridging Fundamental Concepts to Practice [NEW]

8:30 am - 4:30 pm

This course is designed with the new and experienced liquid handling user in mind. With a balanced mix of lecture and hands-on activities, the course focuses on understanding and applying key liquid handling concepts while measuring the outcome on live systems. Best practices and guidance for assessing and maintaining quality pipetting performance are emphasized.

Establishing Cell-Based Assays for Screening This course describes developing standard procedures for handling cultured cells to set up cell-based assays, techniques for measuring cell health and the pathways leading to cytotoxicity, developing siRNA screening assays, and an overview of various GPCR screening methods.

Instructors: Nathaniel Hentz North Carolina State University

Instructors: Eric Johnson Wuxi AppTee

Keith Albert ARTEL

Terry Riss Promega

Dana Campbell ARTEL

Lisa Minor In Vitro Strategies, LLC Geoffrey Bartholomeusz UT M.D. Anderson Cancer Center

Lab-on-a-Chip: From Technology to Bioanalysis on Chip [NEW] This course is aimed at researchers who are interested in learning more about new developments in the technology behind lab-on-a-chip systems. This course is a “how-to” primer that could form the basis for the development of prototypes having integrated functions for a variety of purposes. Instructors: Sabeth Verpoorte University of Groningen Johan Nilsson Lund University

SLAS2015 Short Courses offer a deep dive into key scientific topics.

Jörg P. Kutter University of Copenhagen

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Digital Image Processing and Analysis for the Laboratory Scientist: Theory and Application [NEW]

sunday, february eighth 8:30 am - 4:30 pm

Laptop Required

This course takes a practical, hands-on approach to the application of digital image processing and analysis in a life-sciences laboratory. Diverse techniques and applications are covered. This course prepares the attendees to apply learned methodologies to their own experimental images and to summarize results.

3D Cell-Based Assays for Drug De-Risking The continually rising numbers of compound failures and increasing costs of drug and substance development are fostering the use of biologically more complex cell models. Physiological relevance is a key parameter to improve the predictive power of cell-based assays. The course covers advanced 3D cell culture technologies and their use in substance testing.

Instructors: Matthew Fronheiser Mark F. Russo Rowan University

Instructors: Ursula Graf-Hausner University of Applied Sciences Zurich

High Content Screening: Instrumentation, Assay Development, Screening, Image and Data Analysis

Jens M. Kelm InSphero AG

High-content screening is a powerful technology platform for implementing functional cell-based assays that allow truly multi-parametric analysis in the physiological context of intact cells. This course provides a state-of-the-art overview of the components of HCS (instrumentation, reagents, HC assay development, automated image analysis and multi-parametric data analysis, and data standards) together with some showcases of small molecule and RNAi high-content screens in industry and academia.

Cross Functional Project Management for Technical Professionals [NEW] The course reviews the art and science involved in running successful cross-functional project teams. Course work stresses the planning activities required for success as well as the keys for project execution. This course exposes attendees to the key activities required in planning and managing successful cross-functional projects. Instructor: Barry Weinstein Barry M. Weinstein and Associates

Instructors: Eberhard Krausz ChemBioCon Marc Bickle Max Planck Institute of Molecular Cell Biology and Genetics, Technology Development Studio

Data Management in the Age of Big Data, Mobile, and the Cloud [NEW] This course provides decision makers and practitioners from bio-pharma, health care, and academia with a comprehensive overview of IT trends in laboratory automation, data management and systems integration. It highlights the current hot fields in the area of data management, big data, cloud computing and mobile technologies. This course provides crucial guidance for assessing how these new technologies fit into your laboratory data landscape. Instructor: Burkhard Schaefer BSSN Software

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Lab-on-a-Chip: Biomedical Case Studies [NEW]

sunday, february eighth (cont’d)

This course focuses on the fundamentals of statistics and simple statistical methods that are routinely applied in the bioanalytical laboratory. Topics include review of statistical terms and concepts; study design; assessing bioanalytical measurement quality; fitting equations to bioanalytical data, HTS data normalization and statistical testing.

This course is aimed at researchers who already have a good basis in lab-chip technologies and are interested in exploring biomedical applications, in particular how lab-chip systems have been or could be developed for researchers in cutting-edge drug development and the life sciences. Lectures are presented using a casestudy approach, using a number of selected examples to emphasize which aspects and issues play a deciding role in how a particular system is developed.

Instructors: Liming Shi Eli Lilly and Company

Instructors: Sabeth Verpoorte University of Groningen

Robert Nadon McGill University and Genome Quebec Innovation Centre

Johan Nilsson Lund University

Introduction to Laboratory Automation

JĂśrg P. Kutter University of Copenhagen

Introduction of Quantitative Treatment of Biological Assays in the Bioanalytical Laboratory [NEW]

This course presents a broad introduction to laboratory automation in the R&D laboratory environment (i.e. non-clinical). A general understanding of a laboratory environment is helpful.

Label-Free/Biophysics Methods for Screening Gain an overview on the most relevant biochemical biophysics/ label-free technologies for screening and lead finding. Learn how this novel technologies toolbox helps drug discovery projects. Focus is on biophysics assay applications that allow the detection, quantification and qualification of ligand/protein binding events with suitability for screening and hit follow-up. Learn the strategies of the technologies, key applications in drug discovery projects and usage regarding impact and limitations.

Instructors: Steven D. Hamilton SLAS Director of Education James M. Gill II

Introduction to the Derivation and Maintenance of Human Induced Pluripotent Stem Cells

Instructors: Christine Genick Novartis

This course provides an overview of the basic biology and laboratory techniques required to derive and maintain human induced pluripotent stem cell (iPS) lines from skin fibroblasts. Additional topics include characterization assays for iPS and embryonic stem cells (ES) with emphasis on the use of fluorescence activated cell sorting (FACS) and flow cytometry (FCM) and protocols for the derivation of neural lineage cell lines. Instructors: David J. Kahler NYU Langone Medical Center Justin Ichida University of Southern California

Delphine Collin Boehringer Ingelheim

Learn More in ELN View Here

Kelvin Lam Simplex Pharma Advisors

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Next Generation Sequencing Technology Fundamentals and Applications

Two-Day Short Courses

Next generation sequencing (NGS) technologies allow laboratories to do genome-wide research that was previously only possible at large genome centers. This course teaches key concepts and applications of major sequencing technologies (Illumina, 454, SOLiD, Ion Torrent & PacBio) including their technology basics, sample preps, data analysis and associated IT supports.

saturday, february seventh & sunday, february eighth

Instructors: Dawei Lin National Institutes of Health (NIH)

Excel is widely used in scientific laboratories to automate tedious data manipulation and presentation tasks. This course reviews many of the tools built in to Excel for handling problems commonly encountered in the laboratory. It also introduces the Visual Basic for Applications scripting language as a way to customize Excel and expand upon its functionality.

8:30 am - 4:30 pm Getting Started With Excel & VBA Laptop Required

Ryan Kim University of California, Davis Genome Center

Sample Management: Best Practice, Trends and Challenges

Instructors: William Neil Martin Echols

PRESENTED IN PARTNERSHIP WITH THE INTERNATIONAL SOCIETY FOR BIOLOGICAL AND ENVIRONMENTAL REPOSITORIES (ISBER)

Pharmacokinetics and Pharmacodynamics in Drug Discovery This course is designed to equip biologists and chemists with an understanding of the principles of pharmacology as applied to the drug discovery process. Specifically, the two days are centered on Pharmacokinetics (day one) and Pharmacodynamics (day two). This can be considered as being loosely based on the dose-response relationship as knowledge of both of these variables is needed in the assessment of therapeutic value.

This course provides current status and considered best practice in the discipline of sample management. It focuses on the traditional aspects of compound management (including how to maintain and measure quality of compounds) but covers the synergies and differences in managing biologics. Consideration is given to key challenges and future directions. With the growth and interest in biological sample management the course has been expanded to cover this discipline. Instructors: Sue Holland Crimmin GlaxoSmithKline

Learn More in ELN

Katheryn Shea Precision for Medicine

View Here

Instructor:

Terry Kenakin University of North Carolina School of Medicine

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KEYNOTE PRESENTATIONS

Donald E. Ingber, M.D., Ph.D.

Founding Director, Wyss Institute for Biologically Inspired Engineering at Harvard University

monday, february ninth, 9 - 10 am Donald Ingber is a pioneer of the emerging field of biologically inspired engineering. At the Wyss Institute, he oversees a multifaceted effort to identify the mechanisms that living organisms use to self-assemble from molecules and cells, and to apply these design principles to develop advanced materials and devices for healthcare and to improve sustainability. Ingber has made major contributions to mechanobiology, tissue engineering, tumor angiogenesis, systems biology, and nanobiotechnology. He has also authored more than 375 publications and 85 patents.

Francis Collins, M.D., Ph.D. Director, National Institutes of Health (NIH)

wednesday, february eleventh, 8:30 - 9:30 am As Director of the National Institutes of Health (NIH), Francis S. Collins oversees the work of the largest supporter of biomedical research in the world, spanning the spectrum from basic to clinical research. He is a physician-geneticist noted for his landmark discoveries of disease genes and his leadership of the international Human Genome Project, which culminated in April 2003 with the completion of a finished sequence of the human DNA instruction book. He is also an elected member of the Institute of Medicine and the National Academy of Sciences, was awarded the Presidential Medal of Freedom in November 2007, and received the National Medal of Science in 2009.

Laurie Garrett

Author, journalist and authority on global health issues

wednesday, february eleventh, 3:45 - 4:45 pm Laurie Garrett is one of America’s leading commentators on global health issues. She is the only person to win the three P’s of journalism: the Pulitzer Prize, the Peabody Award, and the Polk Award. She is a Senior Fellow for Global Health at the Council on Foreign Relations, and is the bestselling author of The Coming Plague and Betrayal of Trust. Garrett also served as a script consultant to Contagion, the film directed by Steven Soderbergh and starring Matt Damon. Garrett’s long-awaited third book, now in stores, is called I HEARD THE SIRENS SCREAM: How Americans Responded to the 9/11 and Anthrax Attacks.

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ALLIED ORGANIZATIONS AT SLAS2015:

TRANSFORM YOUR ACCESS SLAS2015 features sessions, news, networking, innovation and unique access made possible by partnerships with other organizations whose missions are complementary to SLAS’s charter of serving the scientific community:

American Chemical Society (ACS) monday and tuesday february ninth and tenth Washington-area members of the American Chemical Society (ACS) will provide one-on-one mentoring and career advice to SLAS2015 attendees.

Laboratory Products Association (LPA) monday, february ninth, 7 - 8 am LPA and SLAS host a special session to announce the preliminary results of the annual North American Survey of Laboratory Purchasing Trends.

Association for Molecular Pathology (AMP) AMP representatives deliver presentations on special diagnostics and biomarkers. Presenters include: Reid Robison, Tute Genomics, and Roger Lebo, Akron Children’s Hospital.

LRIG monday, february ninth, 6:30 - 8:30 pm Late Night With LRIG – Rapid Fire Innovation Session: Sponsored by LRIG, ELRIG and local LRIG chapters; an interactive forum featuring an overview, discussion and open question-and-answer session about new technologies.

International Society for Biological and Environmental Repositories (ISBER) sunday, february eighth ISBER partners with SLAS to deliver the short course Sample Management: Best Practice, Trends and Challenges. Instructors include Sue Holland Crimmin, GlaxoSmithKline, and Katheryn Shea, Precision for Medicine.

Society of Biomolecular Imaging and Informatics (SBI2) tuesday, february tenth, 8 - 9:15 am The HCS/HCA Data and Informatics SIG is presented in partnership with the Society of Biomolecular Imaging and Informatics (SBI2). The SIG actively addresses issues in the area of information technology and fosters discussions, information sharing and meetings among group members and SIG participants at SLAS2015.

For details on these sessions and other strategic alliances at SLAS2015, visit SLAS2015.org.

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Podium Presentations

YOUR PUBLIC SERVICE

Researchers from prominent government labs and agencies deliver several presentations as part of the scientific podium program. A partial listing of these presentations includes:

Government Focus At SLAS2015

Assay Development & Screening Track Presentation: Pattern Recognition for Imaging Assays in High Content Screens

In connection with the DC meeting location, SLAS has assembled a series of presenters and conference activities geared especially towards scientists from government laboratories and agencies. This special lineup of programming includes:

Presenter: Ilya Goldberg, Laboratory of Genetics, NIH/NIA-IRP

Drug Target Strategies Track Presentation: Strategies for the Discovery and Evaluation of Non-Inhibitory Small Molecule Chaperones of Glucocerebrosidase with Therapeutic Potential for the Treatment of Gaucher and Parkinson’s Disorders

SPECIAL SESSION: European Government/

Presenter: Juan Marugan, NIH/National Center for Advancing Translational Sciences (NCATS)

Foundation Drug Discovery Initiatives

monday, february ninth, 10:30 am - 12:30 pm

Informatics Track

(See description on page 11.)

Presentation: The Challenges of Managing Big Data and New Platforms for Quantitating Biology

SPECIAL SESSION: An Evening With NIH

Presenter: Susan Gregurick, National Institute of General Medical Sciences, National Institutes of Health (NIH)

moderated by Chris Austin, Director, NCATS

monday, february ninth, 6:30 - 8:30 pm

Micro/Nano Technologies Track

(See description on page 11.)

Presentation: SpinDx: A Deployable Syndromic-Based Diagnostic System for Detection of Proteins, Nucleic Acids, and Cells

Keynote Presentation

Presenter: Chung-Yan Koh, Sandia National Laboratories

by Francis Collins, Director, National Institutes of Health (NIH)

Check out the SLAS2015 Event Scheduler, available early November 2014, for complete information on these and other presentations.

wednesday, february eleventh, 8:30 - 9:30 am

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The Commercialization of Laboratory Technologies: From Ideas to Reality (presented by the Journal of Laboratory Automation)

SPECIAL SESSIONS AT SLAS2015

Session Chairs: Dean Ho, University of California, Los Angeles and Edward Chow, National University of Singapore monday, february ninth, 3 - 5 pm

SLAS2015 is pleased to host a series of special sessions, each comprised of multiple presentations, dedicated to timely and relevant topical areas.

Topics covered in this session include the process of commercialization and challenges that, when overcome, catalyze the ability to transition a product or technology from benchtop innovation to lasting commercial impact.

European Government/Foundation Drug Discovery Initiatives

• Creativity Beyond the Science: Innovative Ways to Commercialize an Idea in the Global Industry Presenter: Katherine Wang, BRIM Technology

Session Chair: Steven Rees, AstraZeneca monday, february ninth, 10:30 am - 12:30 pm

• Moving Research Innovations to the Market Presenter: Alicia Löffler, Innovation and New Ventures Office, Northwestern University

European governmental and charity agencies are enabling translation of academic discovery into health benefits of economic value by funding the creation of several novel models and approaches to drug discovery. These initiatives have included the development of new compound libraries, the establishment of academic screening centers and the formation of innovative partnerships with industry. Speakers in this special session explore the interaction of these initiatives with academia and pharma, and describe the anticipated benefit of these programs in terms of bringing novel projects into the clinic.

• Opportunities and Challenges in Life Sciences R&D Presenter: Jeremy Caldwell, Third Rock Ventures • Minding the Gaps in Biomedical Technology Translation Presenter: Megan Frisk, Science Translational Medicine/AAAS

An Evening With NIH monday, february ninth, 6:30 - 8:30 pm

Join Chris Austin, Director, National Center for Advancing Translational Sciences (NCATS) as he chairs a special evening event focused on the array of programs, services and capabilities of the National Institutes of Health and how to best navigate the organization.

• Chemical Biology Consortium Sweden – Deliveries Including Scientific Highlights After Five Years Presenter: Annika Jenmalm Jensen, Chemical Biology Consortium

• Facilitated Translation Within NCATS’ TRND and BrIDGs Programs Presenter: John McKew, National Institutes of Health (NIH)

• EU-OPENSCREEN: Chemical Tools for the Life Sciences Presenter: Philip Gribbon, ScreeningPort Hamburg • The European Lead Factory: Game Changing for Innovative Medicine Presenter: Steven van Helden, Pivot Park Screening Centre

• NIH-Industry Partnership to Discover New Therapeutic Uses for Existing Molecules Presenter: Christine Colvis, National Institutes of Health (NIH) Learn more in ELN

• Opening “The Box of Delights” – Accessing Pharma to Enhance Academic Drug Discovery Presenter: Justin Bryans, MRC Technology

• National Center for Advancing Translational Sciences (NCATS) SBIR and STTR Programs: Valuable Resources for Small Businesses Presenter: Lili Portilla, National Institutes of Health (NIH) • NCI Experimental Therapeutics Program Presenter: Barbara Mroczkowski, National Institutes of Health (NIH)

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SLAS INAUGURAL LEADERSHIP FORUM On Sunday and Monday, February 8-9, SLAS is hosting the Society’s first Leadership Forum dedicated to key, strategic-caliber issues related to life science R&D. This is an invitation-only event for executive- and other c-level professionals in the SLAS community. Among the invitees will be past and current leaders of SLAS and its legacy organizations, the Society for Biomolecular Sciences (SBS) and the Association for Laboratory Automation (ALA).

This inaugural program features a panel discussion focusing on the recent publication in the Proceedings of the National Academy of Sciences – “Rescuing US Biomedical Research From Its Systemic Flaws”:

Proceedings of the National Academy of Sciences [2014 111 (26) E2632-E2633] Bruce Alberts, Marc W. Kirschner, Shirley Tilghman, and Harold Varmus, University of California, San Francisco; Harvard Medical School; Princeton University; and National Cancer Institute The long-held but erroneous assumption of never-ending rapid growth in biomedical science has created an unsustainable hypercompetitive system that is discouraging even the most outstanding prospective students from entering our profession – and making it difficult for seasoned investigators to produce their best work. This is a recipe for long-term decline, and the problems cannot be solved with simplistic approaches. Instead, it is time to confront the dangers at hand and rethink some fundamental features of the US biomedical research ecosystem. Read the paper, here.

2015 SLAS Leadership Forum At-A-Glance sunday, february eighth

• Leadership Forum Welcome Reception

Scheduled panelists include:

• Panel Discussion “Rescuing US Biomedical Research From Its Systemic Flaws”

Donald E. Ingber Founding Director, Wyss Institute for Biologically Inspired Engineering at Harvard University

• SLAS2015 Welcome Reception in Exhibition • SLAS President’s Reception

Alicia Löffler Associate Vice President, Innovation and New Ventures, Northwestern University

monday, february ninth • Leadership Forum Breakfast • SLAS2015 Welcome and Opening Keynote Address (8:30 – 10 am)

Rob Nail Co-founder of Velocity 11 and associate founder of Singularity University

Donald E. Ingber Founding Director, Wyss Institute for Biologically Inspired Engineering at Harvard University

James D. Sterling Interim Dean of the College of Natural Sciences; Director of Minerva Labs, Minerva Schools at KGI

• Access to the SLAS2015 Exhibition Hall

Admission to the 2015 SLAS Leadership Forum is by invitation only and requires a separate registration fee of $299.

For more information, or to request an invitation to attend, please contact Suanne Determan of the SLAS Professional Team at sdeterman@slas.org.

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CONFERENCE-AT-A-GLANCE (Schedule Subject to Change) Saturday, February 7, 2015 7:30 am - 5 pm 8:30 am - 4:30 pm

Registration Open Short Courses: Establishing Cell-Based Assays for Screening; Lab-on-a-Chip: From Technology to Bioanalysis on Chip [NEW]; Liquid Handling Essentials - A Hands-On Workshop Bridging Fundamental Concepts to Practice [NEW] Two-Day Courses: Getting Started With Excel & VBA Laptop Required ; Pharmacokinetics and Pharmacodynamics in Drug Discovery

Sunday, February 8, 2015 7:30 am - 7 pm

8:30 am - 4:30 pm

Registration Open Short Courses: 3D Cell-Based Assays for Drug De-Risking; Cross Funtional Project Management for Technical Professionals [NEW]; Data Management in the Age of Big Data, Mobile, and the Cloud [NEW]; Digital Image Processing and Analysis for the Laboratory Scientist: Theorgy and Application [NEW] Laptop Required ; High Content Screening: Instrumentation, Assay Development, Screening, Image and Data Analysis; Introduction of Quantitative Treatment of Biological Assays in the Bioanalytical Laboratory [NEW]; Introduction to Laboratory Automation; Introduction to the Derivation and Maintenance of Human Induced Pluripotent Stem Cells; Lab-on-a-Chip: Biomedical Case Studies [NEW]; Label-Free/Biophysics Methods for Screening; Next Generation Sequencing Technology Fundamentals and Applications; Sample Management: Best Practice, Trends and Challenges Two-Day Courses: Getting Started With Excel & VBA Laptop Required ; Pharmacokinetics and Pharmacodynamics in Drug Discovery

2 - 4:30 pm

2015 SLAS Leadership Forum

4:30 - 7 pm

Exhibition Open

5 - 6 pm

Member Center Special Event: Meet JALA Editor-in-Chief Ed Chow

5 - 6 pm

Member Center Special Event: Meet JBS Editor-in-Chief Bob Campbell

5:30 - 7 pm 7:30 - 9:30 pm

Welcome Reception in Exhibit Hall / Student and Early Career Professional Mixer in Member Center SLAS Student and Early Career Professionals Event at Lucky Strike

Monday, February 9, 2015 6:30 am

Promega Sunrise Run

7 - 8 am

Laboratory Products Association (LPA) Special Session

7 - 8 am

Career Connections: Joanne Kamens Session - Not Networking 101: Building Professional Relationships for Success (Breakfast served)

7:30 am - 6 pm 8 - 8:30 am

Sponsored By:

Registration Open Morning Beverage Break

Join the SLAS Social Media Communities #SLAS2015

Our online communities are growing every day. Stay up-to-date and join in the discussions. Sign-up now!

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Monday, February 9 continued 8:30 - 9 am 9 - 10 am 10 - 10:30 am

Keynote Session: Welcome and Opening Remarks Keynote Speaker: Donald E. Ingber, Founding Director, Wyss Institute for Biologically Inspired Engineering at Harvard University Beverage Break in the Exhibit Hall

10 am - 6:30 pm

Career Connections: ACS Mentoring Sessions / One-on-One Career Counseling Sessions / Job Boards

10 am - 6:30 pm

Exhibition Open

10 am - 6:30 pm

Poster Viewing in Exhibit Hall

Session 1

10:30 am - 12:30 pm

Assay Development and Screening Biochemical and Biophysical Methods in Screening

Automation and High-Throughput Technologies

Bioanalytical Techniques

Machine-Learning Advances in the Life Sciencess

Recent Advances in Membrane Protein Characterization

Micro/Nano Technologies

Informatics Data Analysis Approaches for Cellular, Phenotypic, and High Content Screening

Microphysiological Systems

Special Session

European Government/ Foundation Drug Discovery Initiatives

12:30 - 1:15 pm

Exhibitor Tutorials: Agilent Technologies; ARTEL; Cisbio Bioassays; Festo; IntelliCyt; MaxCyte; TTP Labtech

12:30 - 1:30 pm

Career Connections: Joanne Kamens Session - Smooth Transitions - Top 10 List: Things Scientists Ask About Finding an Industry Job (Bring a box Lunch.)

12:30 - 1:30 pm

Lunch in the Exhibit Hall

12:30 - 1:45 pm

Exhibitor Tutorials: Brooks Automation; DiscoveRx; Labcyte; Thermo Scientific

1 - 3 pm

Poster Presentations (Even Numbered Posters)

2 - 2:45 pm

Exhibitor Tutorials: Genedata; Promega

2:30 - 3 pm

Beverage Break in the Exhibit Hall

2:30 - 4:30 pm Session 2

3 - 5 pm

5 pm

Clinical Chemistry Trainee Council Info Session Assay Development and Screening

Emerging Trends in High Content Screening

Automation and High-Throughput Technologies

Emerging Approaches to High-Throughput Screening of Membrane Bound Targets

Bioanalytical Techniques

Targeted Proteomics

Micro/Nano Technologies

Informatics

The Challenges of Managing Big Data and New Platforms for Quantitating Biology

Diagnostics and Point-of-Care Microdevices

Student Poster Award Announcement

5:30 - 6:30 pm

Reception in Exhibit Hall Celebrating the 2015 SLAS Journal Achievement Award Honorees

6:30 - 8:30 pm

Late Night with LRIG - Rapid-Fire Innovation Session

6:30 - 8:30 pm

Special Session: An Evening With NIH

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Special Session The Commercialization of Laboratory Technologies: From Ideas to Reality (presented by the Journal of Laboratory Automation)


Tuesday, February 10, 2015 7 - 8:15 am

Career Connections: Dan Eustace Session - Mock Interviews: Preparation and Practice for Getting the Jobs You Want (Breakfast served)

7:15 - 9 am

Analytical, Life Science and Diagnostic Association Special Session (Invitation Only)

7:30 - 8 am

Morning Beverage Break

7:30 am - 5:30 pm 8 - 9:15 am

Sponsored By:

Registration Open Special Interest Groups: Academic Drug Discovery and Drug Repurposing (Joint Session); ADMET; Automation Quality Control; HCS/ HCA Data and Informatics; Screen Design and Assay Technology; Technology Transfer and CRO/CMO Project Management; Women Professionals in Science and Technology

9:30 - 10:15 am

Exhibitor Tutorials: CYTOO, Genedata, Promega

9:30 am - 6 pm

Career Connections: ACS Mentoring Sessions / One-on-One Career Counseling Sessions / Job Boards

9:30 am - 6 pm

Exhibition Open

9:30 am - 6 pm

Poster Viewing in the Exhibit Hall

10 - 10:30 am

Beverage Break in the Exhibit Hall

Session 3

10:30 am - 12:30 pm

Assay Development and Screening The Importance of Medicinal Chemistry in Screening

Automation and High-Throughput Technologies

Bioanalytical Techniques

Automating Phenotypic vs. Target Based Discovery: The Past, The Present, The Future

Advances in Analysis in Biological Matrices

Biomarker Discovery and Applications

Biomarkers for Personalized Medicine

Informatics

Facing the Challenges of Data Quality and Reproducibility

12:30 - 1:15 pm

Exhibitor Tutorials: Agilent Technologies, ARTEL, Cisbio Bioassays, Essen BioScience, Festo; TTP Labtech

12:30 - 1:30 pm

Career Connections: Joanne Kamens Session - How to Choose Your Next Lab (Bring a box lunch)

12:30 - 1:30 pm

Lunch Break in the Exhibit Hall

12:30 - 1:45 pm

Exhibitor Tutorial: BioTek Instruments, Brook Automation, Cellular Dynamics International, Labcyte

1 - 3 pm

New Product Award Announcement in Exhibit Hall

2:30 - 3 pm

Beverage Break in the Exhibit Hall

Session 4

3 - 5 pm

5 - 5:30 pm

Digital and Droplet Microfluidics

Poster Presentations (Odd Numbered Posters)

2 - 2:15 pm

2:30 - 4:30 pm

Micro/Nano Technologies

Member Center Event: ORCID Learn About This New Tool for Journal Authors Assay Development and Screening

Natural Products in Screening

Automation and High-Throughput Technologies Flow Based Approaches to High-Throughput Chemistry, Assaying, and Formulation

Biomarker Discovery and Applications

Biomarker Discovery Technologies

Drug Target Strategies Chemical Biology Approaches to Understanding Mechanism of Action

Informatics

Micro/Nano Technologies

Open and Public Sources of Data

Micro and Nanofluidics for Bioanalytical Systems

Passport to Prizes Winners Announced in Exhibit Hall

5 - 6 pm

Exhibition Closing Reception

7 - 10 pm

SLAS2015 Reception at Smithsonian National Air & Space Museum

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Sponsored By:


Wednesday, February 11, 2015 8 - 8:30 am

Morning Beverage Break

8 am - 1:30 pm

Registration Open

8:30 - 9:30 am

Keynote: Francis Collins, Director National Institutes of Health (NIH)

Session 5

9:45 - 11:45 am

11:30 am - 12 pm 11:45 am - 1:15 pm 12 - 1:15 pm Session 6

Assay Development and Screening

Assay Platforms for Biologics

Automation and High-Throughput Technologies

Non-Traditional Automated Technologies for HTS

Biomarker Discovery and Applications

Translational Medicine

Drug Target Strategies

Physiologically Relevant Target Strategies

Micro/Nano Technologies

Informatics Using Mobile, Web, and Cloud Technologies to Improve the Process and Communication of Research

Overcoming Nanotechnologies Challenges

Lunch for Full Conference Participants JALA & JBS Author Workshop: How to Get Your Work Published Special Interest Groups: Automated Sample Preparation of Pharmaceutical Dosage Forms; Informatics; Labware Leachables; Phenotypic Drug Discovery; Sample Management; Standards Initiatives; Stem Cells and 3D Microtissues Assay Development and Screening

1:30 - 3:30 pm

Cell Based Assays and Screening

3:30 - 3:45 pm

Beverage Break

Automation and High-Throughput Technologies Advances in High-Throughput Analytics and Automation

Drug Target Strategies New Approaches for Interrogating High Value Targets

Informatics

Enhancing Lab Automation Via Software

Micro/Nano Technologies

Commericialization Strategies for Micro and Nanofluidic Devies

3:45 - 5 pm

Closing Remarks, Keynote Presenter: Laurie Garrett, Author, journalist and authority on global health issues Announcement of the SLAS Innovation Award Winner

5 - 5:30 pm

Book Signing with Keynote Speaker Laurie Garrett

SLAS Point-to-Point E-News Brief This mobile-friendly weekly e-mail news brief keeps you up to date with SLAS news announcements, deadline reminders and selected industry headlines. Visit SLAS.org to sign up for a free subscription and browse the archives.

16


CONFERENCE SCHEDULE (Schedule Subject to Change) Short Course Program is held on Saturday, February 7 and Sunday, February 8. For complete listing see pages 4-7. Sunday, February 8, 2015 7:30 am - 7 pm

Registration Open

2 - 4:30 pm

2015 SLAS Leadership Forum

4:30 - 7 pm

Exhibition Open

5 - 6 pm

Member Center Special Event: Meet JALA Editor-in-Chief Ed Chow

5 - 6 pm

Member Center Special Event: Meet JBS Editor-in-Chief Bob Campbell

5:30 - 7 pm 7:30 - 9:30 pm

Welcome Reception in Exhibit Hall / Student and Early Career Professionals Mixer in Member Center SLAS Student and Early Career Professionals Event at Lucky Strike

Monday, February 9, 2015 6:30 am

Promega Sunrise Run

7 - 8 am

Laboratory Products Association (LPA) Special Session

7 - 8 am

Career Connections: Joanne Kamens Session - Not Networking 101: Building Professional Relationships for Success (Breakfast served)

7:30 am - 6 pm

Registration Open

8 - 8:30 am

Morning Beverage Break

8:30 - 9 am

Keynote Session: Welcome and Opening Remarks

9 - 10 am 10 - 10:30 am

Keynote Speaker: Donald E. Ingber, Founding Director, Wyss Institute for Biologically Inspired Engineering at Harvard University Beverage Break in the Exhibit Hall

10 am - 6:30 pm

Career Connections: ACS Mentoring Sessions / One-on-One Career Counseling Sessions / Job Boards

10 am - 6:30 pm

Exhibition Open

10 am - 6:30 pm

Poster Viewing in Exhibit Hall

10:30 am - 12:30 pm 10:30 am

Sponsored By:

Assay Development and Screening Biochemical and Biophysical Methods in Screening; Session Chair: J. Fraser Glickman, The Rockefeller University Monitoring Protein:Protein Interactions in Living Cells Using Bioluminescence Resonance Energy Transfer (BRET) – Novel Applications of NanoBRET™ Technology; Graeme Walker, AstraZeneca

11 am

Assay Development and Screening for Difficult Targets Using High-Throughput SPE/ESI/Mass Spectrometry; J. Fraser Glickman, The Rockefeller University

11:30 am

The Use of Virtual Screening, DSF and MicroScale Thermophoresis for the Rapid Identification of Fragments Active Against MEK1; Alexey Rak, Sanofi-Aventis, R&D

12 pm

Screening for Novel Inhibitors of Thymidylate Synthase Using CETSA – A High-Throughput Target Engagement Assay; Thomas Lundbäck, Karolinska Institutet

JALA & JBS Author Workshop: How to Get Your Work Published Wednesday, February 11, 11:45 am - 1:15 pm There are important tips that every prospective author should know before submitting a scientific manuscript for consideration by a peer-reviewed journal. Edward Chow, Ph.D., of National University of Singapore (editor-in-chief of the Journal of Laboratory Automation) shares step-by-step advice on how to design and write scientific research papers more clearly and effectively to improve their chances for successful publication.

17


Monday, February 9 continued 10:30 am - 12:30 pm

Automation and High-Throughput Technologies Machine-Learning Advances in the Life Sciencess; Session Chair: Robert Murphy, Carnegie Mellon University

10:30 am

Machine Learning and Neural Representations of Language Meaning; Tom Mitchell, Carnegie Mellon University

11 am 11:30 am 12 pm 10:30 am - 12:30 pm

A Machine Learning Analysis of Somatic Variants for Identifying Genes and Protein Domains That Influence Breast Cancer Progression; Thomas Peterson, University of Maryland Baltimore County Multitask Learning of Signaling and Regulatory Networks With Application to Studying Human Response to Flu; Siddhartha Jain, Carnegie Mellon University Protein Multi-Location Prediction: Using Bayesian Networks for Location Inter-Dependencies, and a Mixture Model; Ramanuja Simha, University of Delaware Bioanalytical Techniques Recent Advances in Membrane Protein Characterization; Session Chair: Phoebe Stewart, Case Western Reserve University

10:30 am

Conformational Dynamics of GPCRs – Insights for the Rhodopsin System From X-Ray Crystallography and Site-Directed Spin Labeling; Oliver Ernst, University of Toronto

11 am

Novel Technology Combination Dedicated to GPCR Allosteric and Biased Ligand Discovery; Nathalie Rouleau, Domain Therapeutics NA

11:30 am 12 pm

Parallel Screening of Multiple Muscarinic Receptors Using Multiparametric Cell-Based Assays; Emery Smith, Scripps Research Institute Crystallization of Membrane Proteins From Native Sources for X-Ray Crystallography and CryoEM Imaging of Membrane Proteins; Phoebe Stewart, Case Western Reserve University

10:30 am - 12:30 pm

Informatics Data Analysis Approaches for Cellular, Phenotypic, and High Content Screening; Session Chair: Marc Bickle

10:30 am

Uncovering Genetic and Chemical Relationships Using Image-Based Profiling; Anne Carpenter, Broad Institute

11 am 11:30 am 12 pm 10:30 am - 12:30 pm 10:30 am 11 am 11:30 am 12 pm 10:30 am - 12:30 pm 10:30 am 11 am 11:30 am 12 pm

Novel High Content Analytical Pipeline Without Positive Controls for Discovering Unknown Phenotypes; Marc Bickle, Max Planck Institute of Molecular Cell Biology and Genetics Standardizing Secondary Image Analysis With PerkinElmer’s High Content Profiler; Christopher Hale, Amgen Man Versus Machine: Validating, Optimizing, and Predicting Outcomes in a Pipelined Analysis of a Clinical Flow Cytometry Study; Michael Stadnisky, FlowJo, LLC Micro/Nano Technologies Microphysiological Systems; Session Chair: David Eddington, University of Illinois at Chicago Precision Measurements of Neutrophil Migration in Health and Disease; Daniel Irimia, Massachusetts General Hospital, Harvard Medical School 3-D Printed Microfluidic Devices and a New Approach to Drug and Biomarker Discovery; Dana Spence, Michigan State University Skin Printer: Microfluidic Approach for Skin Regeneration and Wound Dressings; Lian Leng, University of Toronto Microtissues Meet Microfluidics: A Body on a Chip Platform Technology Based on a Highly Parallel Standard SBS Layout; Jens Kelm, InSphero Special Session European Government/Foundation Drug Discovery Initiatives; Session Chair: Steve Rees, AstraZeneca Chemical Biology Consortium Sweden – Deliveries Including Scientific Highlights After Five Years; Annika Jenmalm Jensen, Karolinska Institutet, ScilifeLab EU-OPENSCREEN: Chemical Tools for the Life Sciences; Philip Gribbon, ScreeningPort Hamburg The European Lead Factory: Game Changing for Innovative Medicine; Steven van Helden, Pivot Park Screening Centre Opening “The Box of Delights” - Accessing Pharma to Enhance Academic Drug Discovery; Justin Bryans, MRC Technology

12:30 - 1:15 pm

Exhibitor Tutorials: Agilent Technologies; ARTEL; Cisbio Bioassays; Festo; IntelliCyt; MaxCyte; TTP Labtech

12:30 - 1:30 pm

Career Connections: Joanne Kamens Session - Smooth Transitions - Top 10 List: Things Scientists Ask About Finding an Industry Job (Bring a box lunch)

12:30 - 1:30 pm

Lunch in the Exhibit Hall

12:30 - 1:45 pm

Exhibitor Tutorials: Brooks Automation; DiscoveRx; Labcyte; Thermo Scientific

12:45 - 1:45 pm

Special Update: SLAS in Europe

12:45 - 1:45 pm

Special Update: SLAS in Asia

1 - 3 pm

Poster Presentations (Even Numbered Posters)

2 - 2:45 pm

Exhibitor Tutorials: Genedata; Promega

2:30 - 3 pm

Beverage Break in the Exhibit Hall

18


Monday, February 9 continued 2:30 - 4:30 pm 3 - 5 pm 3 pm 3:30 pm 4 pm

Clinical Chemistry Trainee Council Info Session Assay Development and Screening Emerging Trends in High Content Screening; Session Chair: Shawn Burgess, NHGRI, National Institutes of Health (NIH) Pattern Recognition for Imaging Assays in High Content Screens; Ilya Goldberg, Laboratory of Genetics, National Institutes of Health (NIH)/NIA-IRP A New Platform for High-Throughput Discovery of Autophogy Modulators That Does Not Require Engineered Cell Lines; Robbie Narang, IntelliCyt Convenient and Reliable HCS Screening With Distinct 3D Tumor Spheroids; Sebastien Degot, Cytoo

4:30 pm

High-Speed Acquisition of Sensitized Emission FRET in a High Content Imaging Assay; Matthias Fassler, PerkinElmer

3 - 5 pm

Automation and High-Throughput Technologies Emerging Approaches to High-Throughput Screening of Membrane Bound Targets; Session Chair: Andrew Alt, Bristol-Myers Squibb

3 pm 3:30 pm 4 pm

Regulation of GPCR Trafficking as a Therapeutic Target; P. Michael Conn, TTUHSC New Technologies for Discovery, Characterization, and Development of G-Protein-Coupled Receptor and Ion Channel Probes and Therapeutics; C. David Weaver, Vanderbilt University Shining Light Into HTS Applications; Michela Stucchi, Axxam

4:30 pm

Application of Enzyme Fragment Complementation-Based Receptor Dimerization Assays to the Characterization and Optimization of Biologics; Jane Lamerdin, DiscoveRx

3 - 5 pm

Bionalytical Techniques Targeted Proteomics; Session Chair: Jacob Jaffe, Broad Institute

3 pm 3:30 pm 4 pm

Going Wide With Targeted MS Quantification of PTMs: Proteomic Connectivity Maps of Drugs, Genomics, and Disease; Jacob Jaffe, Broad Institute High-Throughput and Reproducible Workflows to Prepare Human Plasma Samples for Proteomic Analysis; Jenny Van Eyk, Cedar-Sinai Medical Center Automation of Apoptotic Protein Quantification for Selection of Combination Chemotherapy; John Koomen, Moffitt Cancer Center

4:30 pm

Translational Medicine Through Targeted Protein Quantitation: A Novel Automated Workflow for Biomarker Validation and Screening and for Clinical Implementation; Selena Larkin, SISCAPA Assay Technologies

3 - 5 pm

Informatics The Challenges of Managing Big Data and New Platforms for Quantitating Biology; Session Chair: Susan Gregurick, National Institute of General Medical Sciences, National Institutes of Health

3 pm 3:30 pm 4 pm

The Challenges of Managing Big Data and New Platforms for Quantitating Biology, Susan Gregurick, National Institutes of Health (NIH) Advantages of Visual Data Exploration Tools in the Analysis of qPCR, Microarray and Other OMICS Based Big Data, Philip Skinner, PerkinElmer Image-Based Label-Free Evaluation of Micro- and Macro-Movement of Cultured Cells; A Promising New Approach for Phenotypic Screening, Shiori Oshima, Sony Corporation

4:30 pm

Tute Genomics: A Cloud-Based Platform for Genetic Diagnosis and Biomarker Discovery, Reid Robison, Tute Genomics

3 - 5 pm

Micro/Nano Technologies Diagnostics and Point-of-Care Microdevices; Session Chair: Bobak Mosadegh, Cornell (Weil College of Medicine)

3 pm 3:30 pm 4 pm

Paper-Based Diagnostics: Meeting Healthcare Needs Across the Globe; Barbara Smith, Arizona State University SpinDx: A Deployable Syndromic-Based Diagnostic System for Detection of Proteins, Nucleic Acids, and Cells; Chung-Yan Koh, Sandia National Laboratories A Universal Microfluidic Immunofiltration System for POC Diagnostic Applications; Claudia Gärtner, microfluidic ChipShop

4:30 pm

Bioinspired Spleen-on-a-Chip for Sepsis Therapy; Joo Hun Kang, Wyss Institute/Harvard University

3 - 5 pm

Special Session The Commercialization of Laboratory Technologies: From Ideas to Reality (presented by the Journal of Laboratory Automation); Session Chairs: Dean Ho, Division of Oral Biology and Medicine; The Jane and Jerry Weintraub Center for Reconstructive Biotechnology; Department of Bioengineering; California NanoSystems Institute; Jonsson Comprehensive Cancer Center; and Edward Chow, National University of Singapore

3 pm 3:30 pm 4 pm 4:30 pm 5 pm

Creativity Beyond the Science: Innovative Ways to Commercialize an Idea in the Global Industry; Katherine Wang, BRIM Biotechnology, Inc. Moving Research Innovations to the Market; Alicia Löffler, Northwestern University Opportunities and Challenges in Life Sciences R&D; Jeremy Caldwell, Third Rock Ventures MInding the Gaps in Biomedical Technology Translation; Megan Frisk, Science Translational Medicine/AAAS Student Poster Award Announcement

19


Monday, February 9 continued 5:30 - 6:30 pm

Reception in Exhibit Hall Celebrating the 2015 SLAS Journal Achievement Award Honorees

6:30 - 8:30 pm

Late Night with LRIG - Rapid-Fire Innovation Session

6:30 - 8:30 pm

Special Session An Evening With NIH; Session Chair: Christopher Austin, National Center for Advancing Translational Sciences (NCATS) Facilitated Translation Within NCATS’ TRND and BrIDGs Programs; John McKew, National Institutes of Health (NIH)/National Center for Advancing Translational Sciences (NCATS) NCI Experimental Therapeutics Program; Barbara Mroczkowski, National Cancer Institute National Center for Advancing Translational Sciences (NCATS) SBIR and STTR Programs: Valuable Resources for Small Businesses; Lili Portilla, National Center For Advancing Translational Sciences (NCATS) NIH-Industry Partnership to Discover New Therapeutic Uses for Existing Molecules; Christine Colvis, National Center for Advancing Translational Sciences (NCATS)

Tuesday, February 10, 2015 7 - 8:15 am

Career Connections: Dan Eustace Session - Mock Interviews: Preparation and Practice for Getting the Jobs You Want (Breakfast served)

7:15 - 9 am

Analytical, Life Science and Diagnostic Association Special Session (Invitation Only)

7:30 - 8 am

Morning Beverage Break

7:30 am - 5:30 pm 8 - 9:15 am

Registration Open Special Interest Groups: Academic Drug Discovery and Drug Repurposing(Joint Session); ADMET; Automation Quality Control; HCS/ HCA Data and Informatics; Screen Design and Assay Technology; Technology Transfer and CRO/CMO Project Management; Women Professionals in Science and Technology

9:30 - 10:15 am

Exhibitor Tutorials: CYTOO, Genedata, Promega

9:30 am - 6 pm

Career Connections: ACS Mentoring Sessions / One-on-One Career Counseling Sessions / Job Boards

9:30 am - 6 pm

Exhibition Open

9:30 am - 6 pm

Poster Viewing in the Exhibit Hall

10 - 10:30 am

Beverage Break in the Exhibit Hall

10:30 am - 12:30 pm 10:30 am 11 am 11:30 am 12 pm

Sponsored By:

Assay Development and Screening The Importance of Medicinal Chemistry in Screening; Session Chair: Michael Walters, University of Minnesota Physicochemical Properties and HTS Triage; Philip Cox, AbbVie Inc. PAINS in the Assays: ALARM NMR and Apparent Structure Activity Relationships as Useful Tools for Investigating the Basis of Promiscuous Bioactivity in Real and Virtual High-Throughput Screens; Jayme Dahlin, Medical Scientist Training Program, Mayo Clinic College of Medicine Increasing the Success of AstraZeneca’s Hit ID Cascades; Mark Wigglesworth, AstraZeneca HES – A Novel Approach to the Automated Discovery of New Drug Leads; Alan Katz, Hudson Robotics, Inc.

10:30 am - 12:30 pm

Automation and High-Throughput Technologies Automating Phenotypic vs. Target Based Discovery: The Past, The Present, The Future; Session Chair: Ralf Schwander, Amgen

10:30 am

Flow Cytometry-Based Phenotypic Screening Combined With Smart Compound Selection Applied to the Identification of Cell Cycle Perturbators; Daniela Brodbeck, Exquiron Biotech AG

11 am 11:30 am 12 pm 10:30 am - 12:30 pm 10:30 am 11 am 11:30 am

Integrated Phenotypic Screening and Untargeted Metabolomics for Natural Products Discovery; Roger Linington, University of California, Santa Cruz An Automated High-Throughput Imaging Screen for the Identification of Anti-Wolbachia Agents (Open Innovation in Practice); Roger Clark, AstraZeneca The Phenotypic Screening “Rule of 3”: Developing More Predictive Assays; Fabien Vincent, Pfizer Bioanalytical Techniques Advances in Analysis in Biological Matrices; Session Chair: Art Morales, Wilson Shou, Bristol-Myers Squibb Affinity Capture Workflows for Novel Target Deconvolution; Shaun McLoughlin, AbbVie Laboratories Strategies to Automating the Preparation of Samples for Quantitative Liquid Chromatography Tandem Mass Spectrometry in Discovery and Clinical Research; Bernard Choi, Merck Research Laboratories Acoustic Sample Deposition Coupled with LDTD-MS/MS Takes High-Throughput MS to the Next Level; Zuzana Haarhoff, Bristol-Myers Squibb

20


Tuesday, February 10 continued 12 pm 10:30 am - 12:30 pm 10:30 am

Novel Acoustic Loading of a Mass Spectrometer – Towards Next Generation High-Throughput MS Screening; Jonathan Wingfield, AstraZeneca Biomarker Discovery and Applications Biomarkers for Personalized Medicine; Session Chair: Mary Savage, Merck The Simoa HD-1 Analyzer: A Fully-Automated, Multiplexed Immunoanalyzer With Single Molecule Sensitivity; David Duffy, Quanterix Corporation

11 am

Zero Background in Homogeneous Proximity Assays Using Thermofluorimetric Analysis (TFA) for Quantitation of Attomole Protein Levels in Serum; Joonyul Kim, Auburn University

11:30 am

An Automated Open Platform for Exclusion-Based Sample Preparation: Getting More Information From Limited Patient Samples; David Guckenberger, University of Wisconsin - Madison

12 pm

Rapid Detection of Human Leukocyte Antigen Cancer Biomarkers Using Label-Free Photonic Biosensor Technology; Jon Weidanz, Texas Tech University Health Sciences Center

10:30 am - 12:30 pm 10:30 am 11 am 11:30 am 12 pm 10:30 am - 12:30 pm 10:30 am 11 am 11:30 am 12 pm

Informatics Facing the Challenges of Data Quality and Reproducibility; Session Chair: Leonard Freedman, Global Biological Standards Institute Reproducibility and Standards in Preclinical Life Science Research; Leonard Freedman, Global Biological Standards Institute The Role of Academic Drug Discovery in De-risking Public Data Mining, Emily Hull-Ryde, Center for Integrative Chemical Biology and Drug Discovery; University of North Carolina at Chapel Hill What is the Current State of RNAi Screening?; Scott Martin, NIH/National Center for Advancing Translational Sciences (NCATS) Presentation Title TBD; Brian Murphy, Bristol-Myers Squibb Micro/Nano Technologies Digital and Droplet Microfluidics; Session Chair: Amar Basu, Wayne State University Digital Microfluidic Immunocytochemistry in Single Cells (DISC); Aaron Wheeler, University of Toronto Rapid Detection of Bacteria and Antimicrobial Resistance in Unprocessed Blood Using the Integrated Comprehensive Droplet Digital Detection (IC 3D) System; Weian Zhao, University of California, Irvine Droplet-Based Three Dimensional Cell Migration Assay With Flow Cytometry Based Automated Analysis; Marie-Elena Brett, University of Minnesota Droplet-Based Microfluidics: Towards Massively Parallel Biological Experimentation; Andrew De Mello, ETH Zürich

12:30 - 1:15 pm

Exhibitor Tutorials: Agilent Technologies, ARTEL, Cisbio Bioassays, Essen BioScience, Festo; TTP Labtech

12:30 - 1:30 pm

Career Connections: Joanne Kamens Session - How to Choose Your Next Lab (Bring a box lunch)

12:30 - 1:30 pm

Lunch Break in the Exhibit Hall

12:30 - 1:45 pm

Exhibitor Tutorial: BioTek Instruments, Brook Automation, Cellular Dynamics International, Labcyte

1 - 3 pm

Poster Presentation (Odd Numbered Posters)

2 - 2:15 pm

New Product Award Announcement in Exhibt Hall

2:30 - 3 pm

Beverage Break in the Exhibit Hall

2:30 - 4:30 pm 3 - 5 pm 3 pm 3:30 pm

Member Center Event: ORCID Learn About This New Tool for Journal Authors Assay Development and Screening Natural Products in Screening; Session Chair: John Beutler, National Cancer Institute (NCI), NIH Natural Product Screening Studies on Disease and Development Signaling Pathways; Masami Ishibashi, Chiba University Meeting the Challenges of Identifying Novel Natural Products and Their Cancer-Related Targets Using Natural Products Chemistry, High-Throughput Phenotypic Screening, and Functional Signature Ontology (FuSiOn); Bruce Posner, UT Southwestern Medical Center

4 pm

Combining Targeted Cell-Based Assays With Sample Processing to Identify Natural Product Modulators of Cancer-Related Targets; Curtis Henrich, Leidos Biomedical Research/National Cancer Institute

4:30 pm

Development a Screening Method for Echinocandin Antifungal Drugs by Capillary Electrophoresis and Laser Induced Fluorescence; Chaohui Sun, Tianjin University

3 – 5 pm

Automation and High-Throughput Technologies Flow Based Approaches to High-Throughput Chemistry, Assaying, and Formulation; Session Chair: Ferenc Darvas, Institute of Innovations

3 pm 3:30 pm 4 pm

High-Throughput Approaches in Medicinal Chemistry; Aaron Beeler, Boston University Qualitative and Quantitative Analysis of ADC Payload by CESI-MS; Andras Guttman, Northeastern University Flow Technology for Improving Bioavailability and ADME Properties of API’s and Drug Candidates by Nanoparticle Formation; Ferenc Darvas, Institute of Innovations

21


Tuesday, February 10 continued 4:30 pm

Fast Flow Peptide Synthesis; Bradley Pentelute, Massachusetts Institute of Technology

3 - 5 pm

Biomarker Discovery and Applications Biomarker Discovery Technologies; Session Chair: David Hirschberg, University of Washington Tacoma, and Geneva Institute

3 pm 3:30 pm 4 pm

Biomarkers for Environmental Surveillance; David Hirschberg, University of Washington Tacoma, and Geneva Institute Using Protein Domain Arrays to Screen for Peptide and Chemical Ligands; Mark Bedford, University of Texas High Content Image Based Screening of a Small Molecule Library Against Host Cellular Pathways Identifies Novel Antivirals Targeting Rift Valley Fever Virus and Several Highly Pathogenic RNA Viruses; Krishna Kota, United States Army Medical Research Institute of Infectious Diseases

4:30 pm

Synthesis and Cell-Free Cloning of DNA Using Programmable Microfluidics; Tuval Ben Yehezkel, SynVaccine and the Weizmann Institute of Science

3 - 5 pm

Drug Target Strategies Chemical Biology Approaches to Understanding Mechanism of Action; Session Chair: Terry Riss, Promega

3 pm

Interrogating Intracellular Drug Affinity and Residence Time to Characterize the Mode of Action of HDAC Inhibitors; Keith Wood, Promega

3:30 pm

Annotating Biological Activities of Compounds by High-Content Pathway Profiling Assays; Sergei Makarov, Attagene

4 pm

Large-Scale Kinase Profiling for Drug Discovery; Jeffrey Peterson, Fox Chase Cancer Center

4:30 pm

New Target Prediction and Visualization Tools Incorporating Open Source Molecular Fingerprints For TB Mobile 2.0; Sean Ekins, Collaborative Drug Discovery

3 - 5 pm

Informatics Open and Public Sources of Data; Session Chair: John Overington, EMBL-EBI

3 pm

Open Data to Support Screening Library Design, Target Deorphanisation and Lead Optimisation; John Overington, EMBL-EBI

3:30 pm

The Open PHACTS Discovery Platform – Semantic Data Integration for Life Sciences; Bryn Williams-Jones, The Open PHACTS Foundation

4 pm

The Allotrope Framework: An Innovative Approach to Improve Data Interchange, Increase Research Efficiency and Maximize the Value of Your Data; James Roberts, GlaxoSmithKline

4:30 pm

Help Maximize the Impact of Your Research: Make Your Data Public!; Benjamin Shoemaker, National Institutes of Health

3 - 5 pm

Micro/Nano Technologies Micro and Nanofluidics for Bioanalytical Systems; Session Chair: Christopher Easley, Auburn University

3 pm 3:30 pm 4 pm 4:30 pm 5 - 5:30 pm

Droplet Microfluidics for High-Throughput Analysis and Sensing; Robert Kennedy, University of Michigan High-Throughput Dynamic Single-Cell Gene Expression Analysis in 3D Organoids and Tissues; Pak Kin Wong, The University of Arizona Integrated Microfluidic Systems for In Vivo Monitoring of Neurotransmitters; Maojun Gong, Wichita State University Tailor-Made Nanoliter Protein Quantitation Through Microfluidics, Proximity Assays, and Thermal Control; Christopher Easley, Auburn University, Chemistry and Biochemistry Passport to Prizes Winners Announced in Exhibit Hall

5 - 6 pm

Exhibition Closing Reception

7 - 10 pm

SLAS2015 Reception at Smithsonian National Air & Space Museum

Sponsored By:

Wednesday, February 11, 2015 8 - 8:30 am

Morning Beverage Break

8 am - 1:30 pm

Registration Open

8:30 - 9:30 am

Keynote: Francis Collins, Director National Institutes of Health (NIH)

9:45 - 11:45 am

Assay Development and Screening Assay Platforms for Biologics; Session Chair: Torben Straight Nissen, Pfizer CTI

9:45 am

Antibodies With Optimal Biotherapeutic Properties From Deep Microfludic Screening; Will Somers, Pfizer

10:15 am

Automated High-Throughput Generation of Bispecific Antibodies Via Controlled Fab-Arm Exchange; Arnout Gerritsen, Genmab bv

10:45 am

Cell Based Assays for Biologics Drug Discovery; Caroline Colley, MedImmune

11:15 am

Developing Functional Monoclonal Antibodies for Beta3 Adrenergic Receptor; Helena Mancebo, Multispan

9:45 - 11:45 am 9:45 am

Automation and High-Throughput Technologies Non-Traditional Automated Technologies for HTS; Session Chair: Louis Scampavia, The Scripps Research Institute Florida Automation of Label-Free Analytical Technologies for Hit Identification and Optimization: An Overview; Thomas Roddy, Beryllium

22


Wednesday, February 11 continued 10:15 am

Application of High-Throughput Mass Spectrometry to Enable Challenging Targets and Reduce False Positives From uHTS Screens; Gregory Adam, Merck

10:45 am

Qube – 384 Well, Automated Patch Clamp; Richard Kondo, Biolin Scientific

11:15 am

96-Well Nanoplasmonic Microplate for Surface Plasmon Resonance Molecular Screening in Regular Microplate Readers; Logan Liu, University of Illinois at Urbana-Champaign

9:45 - 11:45 am

Biomarker Discovery and Applications Translational Medicine; Session Chair: Daniel Chelsky, Caprion Proteomics

9:45 am

Quantifying 190 Proteins in a Single Assay Without Antibodies Using MRM Mass Spectrometry; Daniel Chelsky, Caprion Proteomics

10:15 am

Analyzing the Most Frequent Disease Loci in Targeted Patient Categories Optimizes Disease Gene Identification and Test Accuracy Worldwide; Roger Lebo, Akron Children’s Hospital/Northeast Ohio College of Medicine

10:45 am

Replication of 50 High Impact Preclinical Cancer Studies to Examine Rates of Reproducibility; Tim Errington, Center for Open Science

11:15 am

Biomarker Qualification at CDER, FDA; Shashi Amur, OTS/CDER/FDA

9:45 - 11:45 am

Drug Target Strategies Physiologically Relevant Target Strategies; Session Chair: G. Sitta Sittampalam, National Institutes of Health (NIH)/National Center for Advancing Translational Sciences (NCATS)

9:45 am

A Chemical Biology Approach Using Primary Human Cell Systems and Co-Cultures for Understanding Target Biology; Ellen Berg, BioSeek, a division of DiscoveRx

10:15 am

Combinatorial Approach of Cell and Small Animal Models for Target Validation; Satish Srinivas Kitambi, Karolinska Institutet

10:45 am

Precise Genome Editing and Stem Cell Technologies - Novel Tools for Novel Medicines; Lorenz Mayr, AstraZeneca

11:15 am

Repurposing “Failed” Drugs to Treat Pediatric Sarcomas; Andrew Napper, Nemours Center for Childhood Cancer Research

9:45 - 11:45 am

Informatics Using Mobile, Web, and Cloud Technologies to Improve the Process and Communication of Research; Session Chair: Lenny Teytelman, ZappyLab

9:45 am

Creating a Marketplace for Scientific Collaboration; Elizabeth Iorns, Science Exchange

10:15 am

10 Years Securely Hosting Collaborative Drug Discovery CDD Vault in a Single, Privately Managed “Cloud”; Barry Bunin, Collaborative Drug Discovery (CDD, Inc.)

10:45 am

Getting Credit for All Your Research With figshare; Mark Hahnel, figshare

11:15 am

Protocols.io: Central Repository for the Knowledge That Perishes Because We Do Not Publish It; Lenny Teytelman, ZappyLab

9:45 - 11:45 am

Micro/Nano Technologies Overcoming Nanotechnologies Challenges; Session Chair: Andrew De Mello, ETH Zürich

9:45 am

Tissue-Like Materials From Communicating Droplet Networks; Hagan Bayley

10:15 am

Rapid Detection of Single Bacteria in Unprocessed Blood Using the Integrated Comprehensive Droplet Digital Detection (IC 3D) System; Dong-Ku Kang, University of California, Irvine

10:45 am

In Situ SERS Imaging of Surfactants in Emulsion Interfaces Using Amphiphilic Gold Nanoparticles; Lili He, University of Massachusetts Amherst

11:15 am

Reversible Aptamer-Au Plasmon Rulers for Single-Molecule Detection of Secreted Matrix Metalloproteinases; Somin Eunice Lee, University of Michigan

11:30 am - 12 pm 11:45 am - 1:15 pm 12 - 1:15 pm 1:30 - 3:30 pm 1:30 pm 2 pm 2:30 pm

Lunch for Full Conference Participants JALA & JBS Author Workshop: How to Get Your Work Published Special Interest Groups: Automated Sample Preparation of Pharmaceutical Dosage Forms; Informatics; Labware Leachables; Phenotypic Drug Discovery; Sample Management; Standards Initiatives; Stem Cells and 3D Microtissues Assay Development and Screening Cell Based Assays and Screening; Session Chair: Andrew Napper, Nemours Center for Childhood Cancer Research Spheroid Culture Screening in Anti-Cancer Drug Discovery; David Evans, Frederick National Lab for Cancer Research, Leidos Biomed Rapid In Vivo Chemical Screening Identifies Anti-Metastatic Drugs; Viviana Gallardo, NHGRI/National Institutes of Health (NIH) Identification of Novel Small-Molecule Modulators of CRMP2 Phosphorylation as Lithium Mimetics Using High-Throughput Screening in Human iPSC-Derived Neurons; Wendy Zhao, Massachusetts General Hospital

23


Wednesday, February 11 continued 3 pm

Multi-Phenotype Compound Screening for Cardiac Hypertrophy Using Patient Specific Induced Pluripotent Stem Cell Derived Cardiomyocytes; Ulrich Broeckel, Medical College of Wisconsin

1:30 - 3:30 pm

Automation and High-Throughput Technologies Advances in High-Throughput Analytics and Automation; Session Chair: Roger Bosse, PerkinElmer Life Sciences & Technology

1:30 pm

Spectral High Content Screening of Small Molecules in Live Cells Using Novel Dyes; Jarkko Ylanko, Sunnybrook Research Institute

2 pm 2:30 pm 3 pm 1:30 - 3:30 pm

Pushing the Limits in High-Throughput; Thomas Lade, DuPont Pioneer Research Automation From Brackets to Body Parts - How 3D Printing is Changing the Way We Work; Stephen Trowbridge, GlaxoSmithKline Automated Native Sample Preparation for Proteome Analysis in 384-Well Microplates – Fast, Comprehensive and Precise; Heidrun Rhode, Institute of Biochemistry I, University Hospital Jena Drug Target Strategies New Approaches for Interrogating High Value Targets; Session Chair: Marcie Glicksman, Brigham and Women’s Hospital and Harvard Medical School

1:30 pm

The Future of Kinase Irreversible Inhibitors in Neurodegenerative Diseases; Min Liu, Brigham and Women's Hospital

2 pm

Strategies for the Discovery and Evaluation of Non-Inhibitory Small Molecule Chaperones of Glucocerebrosidase With Therapeutic Potential for the Treatment of Gaucher and Parkinson’s Disorders; Juan Marugan, National Center for Advancing Translational Sciences

2:30 pm

Discovery of an Allosteric JAK Inhibitor Through Primary T Cell High-Throughput Screening; Atli Thorarensen, Pfizer

3 pm 1:30 - 3:30 pm 1:30 pm 2 pm 2:30 pm 3 pm

Kinetics of Activity Enhancement by the NSD2 E1099K and T1150A Mutations and Identification of Selective Inhibitor Compounds; Konrad Howitz, Reaction Biology Corp. Informatics Enhancing Lab Automation Via Software; Session Chair: Jamie McQuay, Scimatic Software Data Driven Automation: Integrating Automation with Informatics Systems; David Dambman, BioSero MSITES: A Powerful Informatics Solution for High-Throughput Screening Centers; Renju Jacob, Center for Chemical Genomics, University of Michigan Escaping Digital Dementia in Lab Automation: A Perspective on Closed Loop Electronic Laboratory Notebooks; Martin Koch, Fraunhofer IPA Real Time Predictive Modeling of Clinical Samples in Transit to Ensure Sample Viability; Jarie Bolander, Lab Sensor Solutions

1:30 - 3:30 pm

Micro/Nano Technologies Commericialization Strategies for Micro and Nanofluidic Devices; Session Chair: Rajiv Bharadwaj, 10x

1:30 pm

Mainstreaming Microfluidics: Keys to Navigating Commercialization; Josh Molho, Zephyrus Biosciences

2 pm 2:30 pm 3 pm 3:30 - 3:45 pm

Automation of Droplet Manipulation Using Electrowetting On Film, Thomas Perroud, Tecan Systems All-in-One Microfluidics Automated Platform for Synthetic Biology; Gregory Linshiz, Lawerence Berkeley National Laboratory Immediate Drop on Demand Technology – A Novel Technology for Cell Dispensing in Nanoliter Range; Lena Schober, Fraunhofer Institute for Manufacturing Engineering and Automation IPA Beverage Break

3:45 - 5 pm

Closing Keynote Speaker Laurie Garrett, Author, journalist and authority on global health issues Announcement of the SLAS Innovation Award Winner

5 - 5:30 pm

Book Signing with Keynote Speaker Laurie Garrett

SLAS Membership Has its Privileges > Significant savings on registration to SLAS conferences CLICK HERE > Unlimited access to SLAS Webinars CLICK HERE > Online access and print subscriptions to JALA and/or JBS CLICK HERE > Exclusive access to the Annual North American Survey of Laboratory Trends CLICK HERE

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Join, renew or update your SLAS membership online. View Here


SPECIAL INTEREST GROUPS (SIGS) SLAS SIGs allow you to connect directly with peers who share similar interests and expertise in specific areas of scientific technology. SIGs are a great way to discuss leading-edge trends, meet recognized experts, and collaborate with like-minded peers. Following is a listing of SLAS SIGs scheduled to meet at SLAS2015.

tuesday, february tenth, 8 - 9:15 am

Academic Drug Discovery and Drug Repurposing (Joint Session) Andrew Napper, Chair The mission of the Academic Drug Discovery SIG is to enable greater interaction between academia, pharmaceutical research companies, suppliers and other technical companies. Through a range of unique programs and events, the Academic Drug Discovery SIG builds bridges between academia and applied sciences. These ties result in better skilled candidates for industry as well as enhanced support for academic centers with programs focused on drug discovery, screening, automation and related disciplines.

Roger Bosse, Chair The SIG on Drug Repurposing is a broad-based Biomolecular Sciences Section initiative allowing its members to proactively address the specific challenges pertaining to their respective fields of expertise (technical, operational, legal, etc.) in relation to needs and benefits of repurposing drugs.

ADMET

integration of higher throughput technologies with methods for determining toxicity, pharmacokinetics and metabolism. The goal is to accelerate the drug discovery pipeline and shorten the time of the development of new drugs that cure illnesses and improve quality of life. This special interest group creates a bridge and network between scientists working in the fields of preclinical research, pharmacology, pharmacokinetics and those who are the producers of combinatorial libraries.

Automation Quality Control John Thomas Bradshaw and Craig Schulz, Chairs The Automation Quality Control SIG provides a forum for discussing topics relating to optimizing performances of laboratory instrumentation. The objective is to encourage development of procedures that should be of interest to instrument vendors and practitioners alike. Specific topics include: • Developing best practices for assessing performance of liquid handlers, microplate readers and integrated systems with a view toward making it easier to compare instruments between vendors and to correlate results across platforms. • Promoting the sharing of experiences and ideas on data formatting during acquisition and export. Techniques and strategies that ease the task of integrating new instrumentation into automated environments are of special interest.

HCS/HCA Data and Informatics Paul Johnston, Chair This SIG is dedicated to sharing best practices, experiences and expertise, and to encouraging collaboration. The group actively addresses issues in the area of information technology and strategies to foster discussions, information sharing and meetings among group members. This SIG is presented in partnership with the Society of Biomolecular Imaging and Informatics (SBI2).

David M. Stresser, Chair

Visit the SLAS SIGs LinkedIn Groups

The mission of the Absorption, Distribution, Metabolism and Toxicology SIG is to advance drug discovery and development by promoting the discussion and dissemination of principles, topics and ideas for the

View Here

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Screen Design and Assay Technology

wednesday, february eleventh, 12 - 1:15 pm

Automated Sample Preparation of Pharmaceutical Dosage Forms

Kenda Evans and Jim Beasley, Chairs The goals of the Screen Design and Assay SIG are to:

Brian Kozlowski and Khanh Ha, Chairs

• Share current best practices and experiences in the design of screens for high- and ultra high-throughput screening programs.

This SIG is dedicated to the discussion of current and future automation platforms used in sample preparation of pharmaceutical dosage forms (tablets, capsules, injectables, blends) for a variety of tests conducted in the industry, including dissolution, composite assay, and content uniformity analysis. A variety of topics are covered, such as establishing equivalency between automated and non-automated methods, handling equipment bias, equipment validation, automation tools used to support formulation development, risk analysis, QbD principles, real-time analytics, stability and release testing, and overall best practices in use of automation. This SIG’s goals are to achieve an industry benchmark for use of automated techniques in drug development and to garner input from key representatives from automation companies.

• Provide a platform to encourage an open discussion of any new screening technologies that can be beneficial to the screening community. • Encourage academic and industrial members to actively contribute to the SIG. • Identify any gaps in reagent(s) and instrumentation and/ or in the screening environment, and seek to influence the appropriate supplier(s). • Evaluate new technologies and instruments on a voluntary basis and share findings at technology-based user group meetings on a more frequent basis.

Technology Transfer and CRO/ CMO Project Management

Informatics

Liming Shi and Raymond Price, Chairs As biopharmaceutical companies seek to increase capacity, free up resources, accelerate clinical timelines, and meet business continuity requirements, technology transfer to contract research organizations (CROs) or contract manufacturing organizations (CMOs) has increased dramatically. This special interest group (SIG) provides a platform for industry colleagues to address and discuss the challenges and key factors considered to be important for achieving successful transfer.

Women Professionals in Science and Technology

Viral Vyas and Dawei Lin, Chairs The SLAS Informatics SIG provides software developers an opportunity to better understand and influence the state of informatics in the laboratory. The focus of this SIG is on systems architecture from the board to the user interface and thus includes topics such as hardware/software interfaces, data management, metadata management, asynchronous coding and operating systems, networking and “big data issues.” The SIG welcomes participation by developers from academia, industry and the vendor community.

Robyn Rourick, Chair The purpose of this group is to establish a collaborative forum for Women Professionals in Science and Technology to connect and create a diverse network for sharing experiences and tools for development and success.

Learn More in ELN View Here

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Labware Leachables

Sample Management

Lynn Rasmussen, Chair

Paul Calvin and Timothy Dawes, Chairs

You know what you added to your assay plate, but do you know what the plate added to your assay? We tend to think of plastics as inert, but they are not. Plastics can bind components from the assay cocktail. This characteristic is exploited for assays like ELISA where the binding of proteins from the solution is required. It can also interfere with the assay if components that need to be in solution bind to the plastic labware. Another phenomena associated with plastic labware is the leaching of chemical entities from the labware into the liquid reagents dispensed to them. Unpolymerized monomers, mold release agents and plasticizers are some of the things that can leach out of the plastic and into your reagents and assays. Higher density plates, with a larger wetted surface area to liquid volume ratio, and new plastics like COC have increased the probability that the labware chemistry could be affecting the assay results.

The Sample Management SIG provides a forum for discussing sample library management issues in the modern drug-discovery high-throughput screening laboratory. Sample libraries include discrete compounds, defined compound mixtures, natural product extracts, and biologics (tissues, cells, DNA, RNA, and antibodies). Topics of critical importance include issues involved in:

Phenotypic Drug Discovery Jonathan Lee, Chair The Phenotypic Drug Discovery (PDD) SIG serves as a discussion forum for the global research community to share/discuss/debate topics related to PDD research. Participants will share their experiences, perceptions, and thoughts on the advantages/disadvantages of PDD and whether/how PDD complements targeted drug discovery (TDD) strategies. Related topics such as target identification/validation, chemical diversity, chemical genomics, chemo-informatics, poly-pharmacology, translational pharmacology, biological model systems and patient tailoring are also in scope.

• Sample Collection: sample acquisition, structural diversity, physical storage, physical manipulation, sample purity and stability. • Materials Management: logistics, information technology, customer support, quality control and systems integration. • Instrumentation and Laboratory Automation: sample preparation, sample retrieval, screening set creation, non-scale technologies, and analytical methodologies.

Standards Initiatives Burkhard Schaefer and Dana Vanderwall, Chairs The Standards Initiatives SIG promotes standardization and interoperability of instruments and data systems in the laboratory. The purpose of this session is to raise awareness of community-driven standardization efforts currently underway. It also provides a forum to foster collaboration between standards initiatives to ensure greater impact and better utilization of community resources.

Stem Cells and 3D Microtissues Marcie Glicksman and Sitta Sittampalam, Chairs The mission of the Stem Cells and 3D Microtissues in Drug Discovery SIG is to promote the discussion and dissemination of information on new enabling technologies related to the use of stem cells and primary cells in drug discovery. This group discusses current developments in stem cell biology, human and mouse pluripotent stem cells, and reprogrammed stem cells. This SIG functions to create a bridge between the network of scientists working in the fields of regenerative medicine, stem cell biology, chemical biology and drug discovery.

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TRANSFORM INNOVATION CELEBRATE EXCELLENCE The Society’s highest honors recognize significant contributions to the field of laboratory science and technology by SLAS members, students, conference participants and companies.

Student Poster Competition This cash award of $500 is awarded to the top three student poster winners at SLAS2015. The winning posters are showcased in the SLAS Member Center and on SLAS2015.org. Additionally, the winners are interviewed by The Lab Man for his blog and podcast. The poster award ceremony takes place Monday, February 9, at 5 pm.

The SLAS Student Poster Competition

$10,000 SLAS Innovation Award

is a launching pad for the work of the next generation of scientists. Read the SLAS ELN feature where SLAS2014 Student Poster Award Winners share their stories.

This $10,000 cash prize award recognizes the work behind one SLAS2015 scientific podium presentation that is exceedingly innovative and contributes to the exploration of technologies in the laboratory. Last year’s winner was Patrick P. Beattie, Diagnostics for All, for his award winning presentation: Paper-Based Sensors for Low-Cost Diagnostics. The Innovation Award winner is named during the closing session of SLAS2015 on Wednesday afternoon, February 11.

SLAS Young Scientist Award SLAS partners with the Institute of Food Technologists (IFT), ELRIG and MipTec to recognize and award the top student poster presenters at their annual conferences. Winners of this prestigious award receive a $500 cash prize, as well as complimentary registration and roundtrip travel and lodging at SLAS2015, where they present their posters.

Tony B. Academic Travel Awards The Tony B. Academic Travel Award Program recognizes up-and-coming researchers from across the globe who demonstrate outstanding achievement and potential in laboratory science and technology. 56 students are attending SLAS2015 as Tony B. awardees. The Tony B. Academic Travel Awards include roundtrip coach airfare, conference registration and hotel accommodations. Each scholarship recipient actively participates in the conference by delivering a podium presentation or a poster. See list of SLAS2015 Tony B. Scholarship winners.

View Here

The 2014 SLAS Young Scientist Award delegates are: Institute of Food Technologists (IFT) Kang Pan, University of Tennessee, Knoxville ph-Driven Encapsulation of Curcumin in Self-Assembled Casein Nanoparticles for Enhanced Dispersibility and Bioactivity ELRIG George Burslem, University of Leeds The Design, Synthesis and Evaluation of Inhibitors of the HIF-1α/p300 Protein-Protein Interaction MipTec Katja-Emilia Lillsunde, University of Helsinki, Finland An Advanced Cellular Assay for Replicon-Based Antiviral Screening of Marine Natural Product

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TRANSFORM YOUR NETWORK With more than 5,000 attendees from across the globe and a diverse set of industry backgrounds, SLAS2015 is an ideal venue to meet fellow researchers, share “tales from the front,” learn from others’ experiences and build a network of professional contacts that can be counted on year-round. From hallway conversations to evening receptions, SLAS2015 is a great way to build both personal and professional relationships. Be sure to bring a healthy supply of business cards.

sunday, february eighth Reception in Exhibit Hall (5:30 - 7 pm) Student and Early Career Professional Reception (7:30 - 9:30 pm)

monday, february ninth Promega Sunrise Run (6:30 am) Reception in Exhibit Hall (5:30 - 6:30 pm)

tuesday, february tenth Reception in Exhibit Hall, with Passport to Prizes awards announcement (5 - 6 pm) SLAS2015 Reception at Smithsonian National Air & Space Museum (7 - 10 pm)

For Runners and Early Morning Sightseers On Monday, February 9, get an early start to your day by participating in the Promega Sunrise Run. Join fellow runners (or walkers) for a 4.2mi/6.8km route that passes by the US Capitol, the Washington Monument, the Lincoln Memorial, and the White House as the sun comes up over the city. The Promega Sunrise Run departs from the Marriott Marquis lobby at 6:30 am. Note: The Sunrise Run is an optional event and is not an official SLAS2015 function.

For Students and Early Career Professionals On the evening of Sunday, February 8, all students and early career professionals attending SLAS2015 are invited to Lucky Strike] where you can relax and mingle with your peers while enjoying an evening of bowling! This evening is FREE to all student and early career attendees, and designed to help you connect and network in an informal setting. The evening includes lane rental, as well as appetizers and non-alcoholic beverages. A cash bar is available.

For International Attendees To help make international attendees feel welcome, the SLAS2015 exhibition area features a Global Village. This venue hosts members of the SLAS professional team from the Society’s Europe and Asia offices. In addition, attendees can use the Global Village as a meeting point to connect with other conference attendees from their home region.

DISCOVER SLAS THROUGH OUR MEMBERS SLAS assists members in advancing their knowledge and careers. Meet SLAS members – and hear their personal stories of success enabled by the Society – in a new video series. Watch the series at www.ourmembers.slas.org

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SLAS2015 RECEPTION AT THE SMITHSONIAN NATIONAL AIR AND SPACE MUSEUM tuesday, february tenth, 7 - 10 pm Join your fellow SLAS2015 attendees for food and drinks to explore the Smithsonian’s National Air and Space Museum on the evening of Tuesday, February 10. The Smithsonian National Air and Space Museum maintains the world’s largest and most significant collection of aviation and space artifacts, encompassing all aspects of human flight, as well as related works of art and archival materials. Included among the thousands of exhibits and displays are the 1903 Wright Flyer, Charles Lindbergh’s Spirit of St. Louis, the Apollo 11 Command Module Columbia, and a lunar rock that you can touch. Complimentary and continuous shuttle bus service for SLAS2015 attendees is provided between the Marriott Marquis and the Museum for this event. Access to this event is free-ofcharge to SLAS2015 registrants.

Generously sponsored by

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Schedule of Special Events and Appearances Meet JALA Editor-in-Chief Ed Chow sunday, february eighth, 5 - 6 pm Talk one-on-one with the new JALA editor-inchief, Edward Kai-Hua Chow, Ph.D., of the Centre for Translational Medicine at the National University of Singapore. Find out how the Journal of Laboratory Automation can further the discoverability and success of your scientific achievements.

SLAS SCIENTIFIC JOURNALS AT SLAS2015

Meet JBS Editor-in-Chief Bob Campbell sunday, february eighth, 5 - 6 pm Visit with the editor-in-chief of the Journal of Biomolecular Screening, Robert M. Campbell, Ph.D., of Eli Lilly and Company, Indianapolis, IN, and find out how you can use JBS to inform and advance your drug discovery research.

SLAS publishes two rigorously peer-reviewed, MEDLINEindexed scientific journals in partnership with SAGE Publications — the Journal of Biomolecular Screening (JBS) and the Journal of Laboratory Automation (JALA). Both journals are celebrating 20 years of publication in 2015. To commemorate this anniversary, a series of special activities is planned throughout SLAS2015.

Clinical Chemistry Trainee Council Info Session monday, february ninth, 2:30 - 4:30 pm Meet the Clinical Chemistry journal’s Managing Editor Sheehan Misko to learn about the Clinical Chemistry Trainee Council and what it offers young professionals.

Visit the SLAS Journals Information Station (located in the SLAS Member Center on the Exhibit Floor) to meet members of the publishing team, learn more about each journal’s editorial scope and find out:

ORCID: Learn About this New Tool for Journal Authors tuesday, Feb. 10 from 2:30 - 4:30 pm

Meet ORCID Executive Director Laure Haak and find out first-hand what the ORCID (Open Researcher and Contributor ID) system is and how you can benefit from it. Plus, register on-the-spot for your own persistent identifier.

• How to search, secure and manage information via JALA Online and JBS Online • How to submit an original scientific manuscript • How to increase awareness, discoverability and citations of your published manuscripts

• How to vote for your favorite finalist in the 2015 JALA & JBS Art of Science Contest

SLAS Author Meet & Greets monday and tuesday, february ninth and tenth (times TBD) Visit the SLAS Member Center to say hello, ask questions and get to know authors of some of JALA and JBS’s most innovative research. Enjoy face-to-face conversations about their work, your work and the new ideas shaping some of today’s most promising research. More information including author names and appearance times to follow.

SLAS journal activities at SLAS2015 also include a Special Session on The Commercialization of Laboratory Technologies: From Ideas to Reality (SEE PAGE 11) and the JALA & JBS Author Workshop: How to Get Your Work Published (SEE PAGE 17)

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SLAS MEMBER CENTER The SLAS Member Center is THE place for members – and nonmembers – to learn everything there is to know about the many year-round benefits and services available through SLAS. Conveniently located in the SLAS2015 Exhibit Hall, the Member Center is central hub for SLAS information and activity, including:

Career Services

Passport to Prizes

Take advantage of FREE career services, see page 33 for additional details.

Play the Passport to Prizes game, and you could win fabulous prizes. To play, simply visit some of the many exhibitors participating in the SLAS2015 Exhibition and have your passport card stamped at their booth. Submit your completed passport to the SLAS Member Center and return for the prize drawing on Tuesday, February 10, at 5 pm. (Only those present at the prize drawing will be eligible to win.)

Live Podcasts With The Lab Man monday, february ninth 5 pm – Interview with the Student Poster Competition Winners

Washington DC Area’s Top F.I.R.S.T. Robotics Teams

tuesday, february tenth 10:30 am – Interview with new SLAS Board members 11 am – Interview with JBS and JALA Editors in Chief Bob Campbell and Ed Chow 4 pm – Interview with the New Product Award winners The Lab Man Schedule is tentative and subject to change.

Award Announcements Student Poster Competition Award winners are announced at 5 pm on Monday, February 9. The SLAS Journal Achievement Awards are announced at the Monday evening reception in the Exhibit Hall. The SLAS2015 New Product Award (NPA) winners are annouced Tuesday, February 10, at 2 pm.

F.I.R.S.T. (For Inspiration and Recognition of Science and Technology) was founded in 1989 by inventor Dean Kamen to inspire an appreciation of science and technology in young people. The F.I.R.S.T. Robotics Competition is a global experience that helps young scientists see the value of education and careers in science, technology, engineering, and math. SLAS is once again proud to welcome F.I.R.S.T. as a partner at SLAS2015.

In addition, in the Member Center you can receive a guided tour of SLAS.org, a review of your SLAS member benefits, and some great giveaways. Members of the SLAS leadership and the Society’s professional team are available to answer questions and point out all that SLAS has to offer to benefit you not only at SLAS2015, but year-round.

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YOUR CAREER Career Workshops

SLAS2015 provides unique access and resources to help you accelerate your career and distinguish yourself in a competitive job market.

Not Networking 101 – Building Professional Relationships for Success

Career Services

Monday, February 9, 7 - 8 am (breakfast served)

Review job postings in the newly redesigned Career Connections section of the SLAS Member Center. Post your résumé for prospective employers. Participate in an individual career coaching session, or have your résumé reviewed by a recognized scientific career expert.

This workshop is designed to reintroduce you to how strong professional relationships can be necessary for most people to succeed in their careers. It provides practical tools for meeting people and for nurturing new and established connections.

Mentoring

Smooth Transitions – Top 10 List: Things Scientists Ask About Finding an Industry Job

Benefit from a mentoring session with an established professional scientist local to DC. Members of American Chemical Society (ACS) will provide complimentary mentoring and career advice. Advance sign-up will be offered through SLAS2015.org.

Monday, February 9, 12:30 - 1:30 pm (bring a box lunch) This presentation provides criteria to consider in deciding if embarking on an industry science career is right for you and then provides concrete tools and resources for preparing for this transition.

Workshops

Mock Interviews: Preparation and Practice for Getting the Jobs You Want Tuesday, February 10, 7 - 8:15 am (breakfast served) Dan Eustace University of Connecticut

Joanne Kamens Addgene

Four different workshops, led by recognized scientific career experts Professor Dan Eustace, University of Connecticut, and Joanne Kamens, Addgene, are offered to hone your credentials, polish your skills and to help you stand out in today’s job market. These workshops are free-of-charge to SLAS2015 attendees, and available on a first-come, first-served basis.

This interactive workshop invites audience members to play active roles participating in, providing feedback for and perhaps coaching how to manage different kinds of interview scenarios.

How to Choose Your Next Lab Tuesday, February 10, 12:30 - 1:30 pm (bring a box lunch) This presentation gives you practical tips on what to look for and how to find it when choosing a new lab for your research. A must-hear for all young scientists.

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TRANSFORM YOUR APPRECIATION OF NEW TECHNOLOGIES

EXHIBITOR TUTORIALS Learn About the Science Behind the Technology As of press time, the following companies are presenting tutorials that offer an in-depth look at topics of ongoing practical interest. Visit SLAS2015.org for the latest list of participating companies and schedule of tutorials.

THE EXHIBITION

monday, february ninth

The exhibition at SLAS2015 features more than 300 leading scientific technology providers showcasing the latest products and services. This venue is a great way to see the latest technologies firsthand, ask questions of expert developers and product managers, and compare offerings that best fit the needs and business objectives of your laboratory. The SLAS2015 Exhibition offers a friendly, welcoming environment where a spirit of collaboration precedes sales pitches. You will leave the SLAS2015 Exhibition better prepared to recommend new products, services and technologies to take your organization to the next level.

Agilent Technologies ARTEL Brooks Automation Cisbio Bioassays DiscoveRx Festo Genedata

tuesday, february tenth

Exhibition Hours Sunday, February 8 Monday, February 9 Tuesday, February 10

IntelliCyt Labcyte MaxCyte Promega Thermo Scientific TTP Labtech

4:30 - 7 pm 10 am - 6:30 pm 9:30 am - 6 pm

SLAS2015 Exhibit Only passes are available free-of-charge. Register for yours at SLAS2015.org.

Agilent Technologies ARTEL BioTek Instruments Brooks Automation Cellular Dynamics International Cisbio Bioassays Corning CYTOO Essen BioScience

The SLAS2015 Exhibition includes: • Exhibitor-led tutorials that provide technical education by exhibiting companies • Innovation AveNEW, a dedicated area of the floor that hosts a select group of emerging companies offering impressive new technologies • The SLAS New Product Award (NPA) designation that recognizes up to three new-and-notable products being showcased in the exhibition • The SLAS Member Center, where you can relax with other attendees, meet SLAS leaders and professional team members, participate in SLAS Journal activities, and sign-up for career services offered at SLAS2015

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Festo Genedata Labcyte Nanion Technologies PerkinElmer Promega Roche Diagnostics Tecan TTP Labtech


EXHIBITOR LISTING For additional information on participating companies and to access the exhibition map, View Here 4titude Ltd Accel Biotech, Inc. ACEA Biosciences, Inc. Advanced Analytical Technologies, Inc.

Cellular Dynamics International Cetoni GmbH ChemBridge Corporation Chemglass Life Sciences

Agilent Technologies Inc.

Chemspeed Technologies AG

AllMotion

Chieftek Precision Co., Ltd.

Alpaqua Engineering LLC

Cisbio US, Inc.

AMRI

Cognex Corporation

amsbio LLC

Collaborative Drug Discovery

Analytical Sales and Services, Inc.

Computype, Inc.

Greiner Bio-One

microfluidic ChipShop GmbH

Grenova LLC

Micronic America

Hamamatsu Corporation

Micronit Microfluidics BV

Hamilton Company

Microsonic Systems Inc.

Helix Linear Technologies

Miltenyi Biotec GmbH

Hettich Instruments

MiniFab

HighRes Biosolutions, Inc.

Minitubes

HIWIN Corporation

MK Fluidic Systems

HNP Mikrosysteme GmbH

Moeller Medical

Horizon Discovery Ltd

Molecular Devices, Inc.

Hudson Robotics, Inc.

Multispan, Inc.

IDBS

Nanion Technologies

Analyticon Discovery LLC

Confluence Discovery Technologies

Andrew Alliance S.A

Core Informatics

IDEA Bio-Medical Ltd

NanoScreen, LLC

Angelantoni Life Science SRL

Corning Incorporated

IDEX Health & Science

NanoTemper Technologies, Inc.

Anton Paar GmbH/USA

Cosmo Biosciences Inc.

Igus, Inc.

Applied BioPhysics, Inc.

Covaris, Inc.

IKO International, Inc.

New England Small Tube Corporation

Apricot Designs

Creoptix AG

ILS

Arc-Tronics

CSEM SA

ImmunoSite Technologies

Art Robbins Instruments

CyBio US Inc.

infoteam Software AG

ARTEL

Cyprotex

INHECO GmbH

Astech Projects Ltd.

DDNews

InSphero AG

Aurora Biomed, Inc.

De Novo Software

INTEGRA Biosciences

Axion Biosystems, Inc.

DiscoveRx Corporation

IntelliCyt Corporation

Axxam SpA

Douglas Scientific

IonField Systems LLC

Beckman Coulter, Inc.

Drug Discovery World

J-Kem Scientific

Bigneat Ltd

Dynamic Devices

J.G. Finneran Associates, Inc.

BINDER, Inc.

E&K Scientific Products Inc.

JoVE

BioAscent Discovery Ltd

Elmo Motion Control, Inc.

JSR Life Sciences

Biodirect Inc.

emp Biotech

Kawator

BioDot, Inc.

Eppendorf

KBiosystems Ltd

BioFocus

EPSON Robots

KMC Systems, Inc.

BioIT Solutions, Inc.

Essen BioScience

KNF Neuberger Inc.

BioMedTech Laboratories, Inc.

Evotec (UK) Ltd

Lab Services B.V.

BioMicroLab, Inc.

Excel Scientific, Inc.

Labcon

BioNex Solutions, Inc.

Exquiron Biotech AG

Labcyte, Inc.

BioSero, LLC

Festo Corporation

LabSmith, Inc.

BioTek Instruments, Inc.

FluidX

LABVANTAGE Solutions, Inc.

Biotix, Inc.

Fluotics, Ltd

LabWare, Inc.

BlueCatBio

Formulatrix, Inc.

Lathrop Engineering Inc.

BMG Labtech, Inc.

Freeslate, Inc.

LEAP Technologies

BPS Bioscience Inc.

Frontier Scientific Services

The Lee Company

Brady Corporation

GenCell Biosystems Ltd

LiCONiC

BrandTech Scientific, Inc.

Genedata, Inc.

Lin Engineering, Inc.

Brookline Scientific Ltd

Genetic Engineering & Biotechnology News

LVL Technologies GmbH & CoKG

Gilson, Inc.

MaxCyte, Inc.

Schaeffler Group USA

GNF Systems

Maxon Precision Motors, Inc.

Schneider Electric Motion USA

MeCour Temperature Control

SCIENION AG

Brooks Automation BSSN Software Burkert Fluid Control Systems

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Scientific Device Laboratory, Inc. Scigilian Software, Inc. Scinomix, Inc. Seahorse Bioscience SelectScience Seyonic SA Sias AG Sigma-Aldrich SiLA Consortium SMC Corporation of America Solid State Cooling Systems Sophion Bioscience A/S Sparton Specs Spectial Instruments

Nippon Pulse America, Inc.

SPEX SamplePrep LLC

Nova Biostorage Plus, LLC

STACS DNA, Inc.

Omega Bio-Tek, Inc.

STRATEC Biomedical AG

Omni International, Inc.

TAP Biosystems

Opticon, Inc.

Tecan

Oriental Motor USA Corp.

Technology Networks Ltd

Panasonic Healthcare

Tek-Matic, Inc.

Panasonic Industrial Devices

Thermo Scientific

Parker

Thorlabs

Peak Analysis and Automation

Titian Software

PerkinElmer

TOMTEC

PHENIX Research Products

Torrey Pines Scientific, Inc.

Plastic Design Corporation

TriContinent

Precise Automation

Trinean

Precision Bioservices

TTP LabTech

Prior Scientific, Inc.

TubeWriter

Pro-Dex OMS

TWD TradeWinds, Inc.

Promega Corporation

UNIConnect

ProQinase GmbH

Union Biometrica, Inc.

PSS (Precision System Science)

USA Scientific, Inc.

QIAGEN Sciences, Inc.

V&P Scientific, Inc.

Quantifoil Instruments GmbH

VICI Valco Instruments

Reaction Biology Corp

Wako Automation

Renishaw, Inc.

Weidmann Plastics Technology AG

Retisoft, Inc. Roche RURO, Inc. SAMDI Tech, Inc. Sarstedt, Inc.

Wyatt Technology Corporation Xavo Systems AG Zinsser Analytic


REGISTRATION AND HOTEL ACCOMMODATIONS Registration SLAS2015 is pleased to offer significant registration discounts to advance registrants, for groups of registrants from the same industry organization, for professionals from academic institutions and government agencies, and for students. Deepest early-bird discounts are available for SLAS members who register by October 31, 2014. (Become an SLAS member to take advantage of these discounts, plus receive year-round benefits through the end of 2015 for just one year’s dues.) Advance discounts are available through January 9, 2015. Group discounts are offered for organizations that send at least five (5) employees who register in advance and at the same time. Student registrants are not eligible for SLAS2015 Group Discounts. See terms and conditions for Group Registration discounts at SLAS2015.org.

Hotel Accommodations SLAS2015 takes place at the Walter E. Washington Convention Center, 801 Mt Vernon Place NW, Washington, DC 20001. SLAS2015 has negotiated discounted rates for conference attendees at two of Washington’s premier hotels, the Marriott Marquis Washington, DC [SLAS2015 Headquarters, located closest to the Walter E. Washington Convention Center and connected to the convention center via an indoor underground walkway] and the Renaissance Washington, DC, Downtown.

Marriott Marquis Washington, DC (Headquarters Hotel) 901 Massachusetts Avenue NW, Washington, DC, 20001 Telephone Reservations: +1.800.393.2505 (reference SLAS2015 when calling)

To reserve your room online using official SLAS2015 channels, visit the Housing and Travel page of SLAS2015.org. The deadline for booking hotel accommodations at the negotiated SLAS2015 rate is January 7, 2015.

The Benefits of Using Official SLAS2015 Reservation Systems and Hotels SLAS2015 has negotiated special rates and benefits for conference attendees at two of Washington, DC’s premier hotels, including the brand new Marriott Marquis Washington, DC, and the Renaissance Washington, DC Downtown. Not only are these hotels conveniently located adjacent to the convention center, but SLAS2015 attendees benefit in several other ways: • Significant discounts off standard guest room rates • Complimentary guest room Internet service (value of up to $12.95 + tax per night) • Flexible booking policies • Simplified ability to make reservation changes, if required By staying in the SLAS block of guest rooms, SLAS is able to contract premier facilities such as the Walter E. Washington Convention Center. Additionally, you are helping the Society meet its contractual obligations to the hotels, avoid penalties and help to underwrite the cost of convention center rental, therefore keeping conference registration fees as affordable as possible. Your support of booking your room within the SLAS2015 guest room block is greatly appreciated. For additional information and to reserve a room through official SLAS reservation channels, View Here.

Renaissance Washington, DC Downtown 999 Ninth Street NW, Washington, DC, 20001 Telephone Reservations: +1.800.393.2505 (reference SLAS2015 when calling)

36


TRAVEL INFORMATION Air Travel Information

Amtrak Information

You may book your air travel directly with SLAS2015’s official travel agent, National Travel at:

Amtrak offers SLAS2015 participants a 10% discount on fares to/from Washington, DC, over the travel dates of February 4 - 14, 2015. To book your reservation, call Amtrak at +1.800.872.7245 and be sure to refer to Convention Fare Code X28T-908 when making your reservation to ensure the 10% discount is applied.

vipservices@nationaltravel.com; +1.800.557.0842 (toll free); +1.304.357.0808 (international) There are three international airports serving the Washington, DC, area: • Reagan National Airport (DCA) • Dulles International Airport (IAD) • Baltimore-Washington International Thurgood Marshall Airport (BWI)

Airport Transportation Information From Reagan National Airport (DCA) Reagan National Airport is the closest airport to the convention center and official SLAS2015 hotels and is also the only airport with Metro access. Metrorail Stop: Yellow line to Mt Vernon stop Taxi Cab: Approximately 20 min (w/o traffic); approximately $45 one way

Union Station in Washington, DC is approximately 1.3 miles from the Walter E. Washington Convention Center and official hotels. Metrorail Stop: Red line toward Shady Grove/Grosvenor; Change trains at Gallery Place then Yellow line to Mt Vernon stop Taxi Cab: Approximately 5 min (w/o traffic); approximately $8 one-way

Rental Car Information National Travel can also assist you in adding a rental car to your existing reservation or in booking a rental car as a stand-alone reservation: vipservices@nationaltravel.com; +1.800.557.0842 (toll free); +1.304.357.0808 (international)

From Baltimore/Washington International Thurgood Marshall Airport (BWI) Taxi Cab: Approximately 60 min (w/o traffic); approximately $90 one-way

From Dulles International Airport (IAD) Taxi Cab: Approximately 45 min (w/o traffic); approximately $64 one-way

37


SLAS BOARD OF DIRECTORS AND CONFERENCE COMMITTEES SLAS2015 Scientific Program Planning Committee

SLAS Scientific Program Advisory Committee

SLAS2015 Conference Chairs

Jim Inglese National Institutes of Health (NIH)

Elliot Hui University of California, Irvine

Assay Development and Screening Track

Biomarker Discovery and Applications Track

Anton Simeonov, Chair National Institutes of Health (NIH)

Daniel Chelsky, Chair Caprion Proteomics

J. Fraser Glickman, Associate Chair Rockefeller University

Automation and High-Throughput Technologies Track Alex Godfrey, Chair Eli Lilly and Company Timothy Spicer, Associate Chair Scripps Research Institute

Bioanalytical Techniques Track Peter Grandsard, Chair Amgen Wilson Shou, Associate Chair Bristol-Myers Squibb

Jonathan O’Connell, Chair Forma Therapeutics

David Eddington University of Illinois at Chicago

Doug Auld Novartis

Elliot Hui University of California, Irvine

Josh Bittker Broad Institute

Jim Inglese National Institutes of Health (NIH)

Michele Cleary Merck Dino DiCarlo University of California, Los Angeles

Aaron Wheeler University of Toronto

Short Course and SIG Coordinators

David Hirschberg, Associate Chair Columbia University

Sue Holland-Crimmin, Chair GlaxoSmithKline

Drug Target Strategies Track

Burkhard Schaefer BSSN Software

Andrew Napper Martin Valler Nemours Center for Childhood Boehringer Ingelheim Cancer Research Pharma GmbH & Co. KG

Marcie Glicksman, Chair Harvard NeuroDiscovery Michelle Arkin, Associate Chair University of California, San Francisco

SLAS Board of Directors Daniel G. Sipes, 2014-15 SLAS President Genomics Institute of the Novartis Research Foundation

Informatics Track Dana Vanderwall, Chair Bristol-Myers Squibb

Alastair Binnie Bristol Myers-Squibb

Ellen Berg, Associate Chair Bioseek

Joshua Bittker Broad Institute

Micro/Nano Technologies Track

Richard Eglen Corning Life Sciences

Sumita Pennathur, Chair University of California, Santa Barbara

Richard Ellson Labcyte

Daniel Huh, Associate Chair University of Pennsylvania

38

Frank Fan Promega Dean Ho University of California, Los Angeles Robyn Rourick Genentech Mike Snowden AstraZeneca


PENNATHUR

The SLAS Electronic Laboratory Neighborhood ... ... is a place for laboratory science and technology professionals to learn more about like-minded colleagues and their personal and professional achievements. It brings the SLAS scientific community to life with real stories by and about real people. From Singapore to Seattle to Stockholm, eager postdocs, seasoned Nobel Laureates, and those who work diligently at benchtops and in classrooms share their ideas, hopes and fears in this friendly and informative international neighborhood.

Meet Your Neighbors: •

Lynn Rasmussen: Labware Leachables

Josh Kangas: Building an Engine for a Start-up Business

John Joslin: Flow Cytometry Powers HTS Advances

Lorenz Mayr: Listen to the Data

Eric Pei-Yu Chiou and Hideaki Tsutsui: JALA Guest Editors

Cynthia Yin: Greeting a Bright Future in Science

Roger Bosse and Mathieu Arcand: Drug Repurposing

Small Molecule Profiling: Dealing with the Data

Sharing experience and perspective on science-related topics, this open access membership e-zine is an official publication of the Society for Laboratory Automation and Screening (SLAS). Visit eln.slas.org.

If you have story suggestions, please e-mail eln@slas.org.

39

FU

eln.slas.org

ARCAND

BRIDEAU

Welcome to the Neighborhood!


Exclusive Premier Sponsor:

SLAS gratefully thanks Hamilton for underwriting many of this year’s conference activities.

Diamond Sponsors:

Platinum Sponsors:

Gold Sponsors:

Silver Sponsor:

TM

To reserve your sponsorship or for more information please contact: Mary Michalik, Sponsorship Manager; mmichalik@SLAS.org; +1.312.265.9650

40


SLAS2015 MEDIA PARTNERS

41


, SHORT COURSES: february / seven – eight CONFERENCE:

february / nine – eleven

EXHIBITION:

february / eight – ten

CONFERENCE AND SHORT COURSE REGISTRATION FORM Register online at SLAS2015.org or complete this form. A $50 cancellation fee will be charged on cancellations received on or before December 19, 2014. No refunds will be given on cancellations received after December 19, 2014. First Name

Last Name

Job Title/Year Hired

Company Name

q Work q Home Preferred Mailing Address

Street Address

City

State/Province

Telephone

Fax

Zip/Postal Code

Country

Email

q Check this box if you do not wish to be included in promotional mailings from SLAS2015 Exhibitors. Your Organization’s Primary Sector: (check one only) q Academia/University

q Agriculture Sciences

q Chemical Industry

q Clinical Diagnostics

q Consultancy

q Consumer Products

q Contract Service Provider

q Energy/Fuel

q Food Science

q Government

q Hospital/Clinic/Healthcare

q Medical/Diagnostic Devices

q Non-profit

q Pharmaceutical/Biopharmaceutical/ Therapeutics

q Technology/Instruments Provider

q None of the above

q Not involved in purchasing decisions

q Specify products/releases

Indicate Role in Purchasing Process: (check one only) q Approver/Final Decision Maker

q Influencer

q None of the above Indicate Your Primary Job Function: (check one only) q Academic Administration Dean, Dept. Head)

q Academic Faculty/Researcher (Professor, Instructor, PI)

q Academic Post-Doctoral

q Academic Graduate Student

q Academic Undergraduate

q Administrative

q Consultant

q Legal

q Licensing/Tech Transfer

q Management (Director, Manager, Department Head)

q Media

q Purchasing

q Retired

q Sales/Marketing/Business Development

q Senior Management (CEO, VP)

q Scientist/Researcher/Engineer/ Technician

q None of the above Indicate Your Primary Interest Area: (check one only) q Analytical Chemistry/Quantitative Biology

q Basic Research

q Diagnostics

q Drug Development

q Drug Discovery

q Genomics

q Healthcare

q Informatics/Bioinformatics/ Computational Science

q Laboratory Instrumentation/ Technology

q Medical Devices

q Micro/Nano Technology

q Synthetic Chemistry

q Tech Transfer Conference Track in Which You Are Most Interested: (check one only) q Assay Development and Screening

q Automation and High-Throughput Technologies

q Bioanalytical Techniques

q Drug Target Strategies

q Informatics

q Micro/Nano Technologies

q Biomarker Discovery and Applications

Levels of Membership: (For additional membership information visit: www.slas.org/membership) Individual q Biomolecular Sciences Section (BSS) - $120 q Laboratory Automation Section (LAS) - $120 q Combined Section - $200

Early Career Professionals q Biomolecular Sciences Section (BSS) - $60 q Laboratory Automation Section (LAS) - $60 q Combined Section - $100

Emerging Economies q Biomolecular Sciences Section (BSS) - $60 q Laboratory Automation Section (LAS) - $60 q Combined Section - $100

Retired q Biomolecular Sciences Section (BSS) - $60 q Laboratory Automation Section (LAS) - $60 q Combined Section - $100

Student q Biomolecular Sciences Section (BSS) - $25 q Laboratory Automation Section (LAS) - $25 q Combined Section - $50

continued on next page.


CONFERENCE AND SHORT COURSE REGISTRATION FORM CONT. Conference Registration

Between November 1, 2014 and January 9, 2015

On or Before October 31, 2014

(Registration Fees)

After January 9, 2015

SLAS Member

SLAS Non-Member

SLAS Member

SLAS Non-Member

SLAS Member

SLAS Non-Member

q Industry Participant

$810

$1,050

$900

$1,050

$1,100

$1,250

q Academic/Government Participant

$540

$750

$600

$750

$700

$850

q Student Participant

$75

$100

$75

$100

$75

$100

FREE

FREE

FREE

FREE

FREE

FREE

q Exhibition Only Participant (Registration is required. Those without badges will not be allowed access to the Exhibition.)

Short Courses

Check box of selected course. (Short Course only registration is available and includes entrance into the Exhibition.)

IMPORTANT NOTE: Courses below listed as “Laptop Required” require registrants to bring their own computer. Internet and charging stations are provided free of charge in each course room. Software specifics are included at www.slas2015.org.

Course Hours

Industry Member

Industry Non-Member

Academic/ Government Member

Academic/ Government Non-Member

Student

q Establishing Cell-Based Assays for Screening

8:30 am - 4:30 pm

$650

$750

$400

$500

$75

q Lab-on-a-Chip: From Technology to Bioanalysis on Chip (NEW!)

8:30 am - 4:30 pm

$650

$750

$400

$500

$75

q Liquid Handling Essentials (Hands On) (NEW!)

8:30 am - 4:30 pm

$850

$950

$550

$650

N/A

q 3D Cell-Based Assays for Drug De-Risking

8:30 am - 4:30 pm

$650

$750

$400

$500

$75

q Cross Functional Project Management for Technical Professional (NEW!)

8:30 am - 4:30 pm

$650

$750

$400

$500

$75

q Data Management in the Age of Big Data, Mobile, and the Cloud (NEW!)

8:30 am - 4:30 pm

$650

$750

$400

$500

$75

q Digital Image Processing and Analysis for the Laboratory Scientist: Theory and Application (Laptop Required) (NEW!)

8:30 am - 4:30 pm

$650

$750

$400

$500

$75

q High Content Screening: Instrumentation, Assay Development, Screening, Image and Data Analysis

8:30 am - 4:30 pm

$650

$750

$400

$500

$75

q Introduction of Quantitative Treatment of Biological Assays in the Bioanalytical Laboratory (NEW!)

8:30 am - 4:30 pm

$650

$750

$400

$500

$75

q Introduction to Laboratory Automation

8:30 am - 4:30 pm

$650

$750

$400

$500

$75

q Introduction to the Derivation and Maintenance of Human Induced Pluripotent Stem Cells

8:30 am - 4:30 pm

$650

$750

$400

$500

$75

q Lab-on-a-Chip: Biomedical Case Studies (NEW!)

8:30 am - 4:30 pm

$650

$750

$400

$500

$75

q Label-Free/Biophysical Methods for Screening

8:30 am - 4:30 pm

$650

$750

$400

$500

$75

q Next Generation Sequencing Technology Fundamentals and Applications

8:30 am - 4:30 pm

$650

$750

$400

$500

$75

q Sample Management: Best Practice, Trends and Challenges

8:30 am - 4:30 pm

$650

$750

$400

$500

$75

COURSE TITLE ONE DAY COURSE: DATE: Saturday, February 7, 2015

ONE DAY COURSE: DATE: Sunday, February 8, 2015

TWO DAY COURSE: DATE: Saturday, February 7 & Sunday, February 8, 2015 q Getting Started with Excel & VBA (Laptop Required)

8:30 am - 4:30 pm

$1,300

$1,500

$800

$1,000

$150

q Pharmacokinetics and Pharmacodynamics in Drug Discovery

8:30 am - 4:30 pm

$1,300

$1,500

$800

$1,000

$150

Questions? +1.866.878.0747 (toll free in US Only) or +1.708.486.0747 • Send to: SLAS2015 Registration, P.O. Box 6271, Broadview, IL 60155-6271 or +1.708.344.4444 [fax]

CONFERENCE PAYMENT: Enter conference registration amount $________ Enter short course amount $________ Enter membership amount $________ Total amount $________ Please include payment for the total amount. q Check enclosed (U.S. funds, payable through U.S. bank). Please make checks payable to SLAS2015. q Credit Card: MasterCard, Visa, American Express, Discover number

Exp. Date

Authorized Signature

Name as it Appears on Card

Terms and Conditions: By signing this SLAS2015 registration form, I “the conferee” acknowledge and agree to the terms and conditions as posted on the SLAS2015 website (SLAS2015.org). Signature

Should you require special assistance due to a medical disability, please contact SLAS Headquarters at +1.877.990.SLAS (7527)


SLAS2015 Preliminary Program