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INNER INNERIDENTITY IDENTITY

DSM DSMNutritional NutritionalProducts Productsisisthe theworld’s world’sleading leadingsupplier supplierofof vitamins, vitamins,carotenoids, carotenoids,enzymes, enzymes,eubiotics eubioticsand and micronutrient micronutrientpremixes premixestotothe theAnimal Animaland andHuman HumanNutrition Nutrition and andHealth HealthIndustries. Industries.

DSM DSMNutritional NutritionalProducts Products(UK) (UK)Ltd. Ltd. Heanor HeanorGate, Gate,Heanor, Heanor,Derbyshire, Derbyshire,DE75 DE757SG 7SG Tel: Tel:01773 01773536 536500 500 www.dsmnutritionalproducts.com www.dsmnutritionalproducts.com

Traceability Traceabilityisisaavital vitalcomponent componentofoffood foodsafety. safety.DSM DSMhave have developed developedaasophisticated sophisticatedglobal globalsystem systemwhich whichmeans meanswe we can canundertake undertaketrack trackand andtrace tracewithin withinminutes. minutes.Because Because we wemanufacture manufactureour ourrange rangeofofROVIMIX® ROVIMIX®vitamins vitaminsalong along with withother otherkey keymicronutrients, micronutrients,we wehave haveaaunique uniqueability abilitytoto control controlthe theorigin originand andsafety safetyofofour ourproducts. products.We Wehave haveaa track trackrecord recordyou youcan canrely relyon. on.

For Fordetails detailsofofproduct productrange, range,see seepage page392. 392.

Cover 2009.indd 1

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More profit per pig worldwide, with Denagard

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Multi-sourced finishing pigs with mixed disease backgrounds continue to be a problem for UK producers. In order to assess the cost-benefits of medication strategies with Denagard in these circumstances, a number of local on-farm studies were carried out. These results show that Denagard consistently delivers superior profit returns for the major economic diseases of swine when compared to other commonly used antibiotics.

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Denagard is licensed for the prevention and treatment of Brachyspira hyodysenteriae (the cause of Swine Dysentery), Mycoplasma hyopneumoniae and M. hyosynoviae to deliver maximum pig performance.



The proven in-vitro activity of Denagard against other key pathogens such as Brachyspira pilosicoli and Lawsonia intracellularis remains undiminished and it is compatible with chlortetracycline for the control of mixed enteric and respiratory infections.

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So choose a product with a full range of formulations and a proven track record and see the difference Denagard makes to your pigs‌ and your profits.

For more information on the cost-benefit of Denagard please consult your veterinary surgeon or: Novartis Animal Health, Frimley Business Park, Frimley, Camberley, Surrey GU16 7SR. Tel: 01276 694402 Fax: 01276 694403 DenagardÂŽ is a registered trademark of Novartis AG, Basel, Switzerland. PP72/2007

Cover 2009.indd 2

Š 2007 Novartis Animal Health Inc. Legal category – POM-V

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05/02/2009 11:00:03


Handbook of

FEED ADDITIVES 2009 Editor

Simon P Mounsey BSc (Hons)

Publisher

Simon Mounsey Ltd Rye House 47 Oakfield Avenue Somersall Chesterfield S40 3LE United Kingdom Phone:

01246 569967

Fax:

01246 567932

E-mail: Website:

mail@simonmounsey.com www.simonmounsey.com

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Twenty-Seventh Edition • February 2009 Š Simon Mounsey Ltd 2009 Copyright in the material included in the Handbook is reserved by the individual suppliers and, where appropriate, by the publishers. ISSN 0957-2368 ISBN 1-872246-41-9

Responsibility for the product information contained in this Handbook is vested in the individual suppliers concerned. Whilst every care has been taken to ensure the accuracy of each entry, the publishers can accept no responsibility for any error or misleading statements which may inadvertently have been included. Neither can they accept any responsibility for the consequences of actions arising from any such errors or misleading statements. However, to the best of our knowledge, all information is correct at the time of going to press. In any case of doubt, the individual supplier concerned should be consulted. A number of users of the Handbook have requested that products designed to be included in drinking water should also be listed. As a consequence, the publishers have informed suppliers that details relating to products for administration to animals via the water will also be included if submitted; a number of such products are, therefore, present in this publication. Users of the Handbook are reminded that products licensed only for use in the drinking water must not be included in feed. Our aim with each edition of this Handbook is to ensure that information included is up-to-date and as comprehensive as possible. Clearly, this can only be achieved with the total co-operation of the suppliers. Products which could be included in this Handbook are sometimes omitted, either because essential preconditions have not been met by the supplier, or because the supplier has decided that they do not wish for some or all of their products to be included. Therefore, because details relating to any product have not been included, it should not be assumed that it is no longer available. Interested persons should contact the publishers or the supplier for guidance on these matters.

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21896 Crack Feed Additives Ad:Layout 1

13/1/09

12:00

Page 1

A contract manufacturer that blends in!

Crack Processing can provide you with a contract outsourcing service that will blend in seamlessly with your own operation whether you need blending, granulation or milling: Professional

-

we are registered for Animal Feed (Additives and Pre-Mixes) Manufacture

Experience

-

we have been blending powders for blue chip customers since 1927

Relationship -

our philosophy is that we operate as an extension of your production facilities

Flexibility

we’ll do everything we can to accommodate your production needs, responding quickly to all requests

-

For more information on how Crack Processing can blend in with your production process, contact our sales team, Ted Harrison on 07990 890635 or Martyn Proctor on 07889 181878 Crack Processing, PO Box 270, Brenda Road, Hartlepool, UK TS25 2BW T: +44 (0) 1429 230340 F: +44 (0) 1429 232996

PROCESSING

ww w.crackprocessing.com


Important notes This 2009 edition of Handbook of Feed Additives uses colour in the product listings section to differentiate between Medicinal Additives, Non-Antibiotic Growth Promoters and Specified Feed Additives (product names in deep red) and Other Additives (product names in green). Colour has also been used to highlight important changes in product details since last year’s edition. All products to which important changes have been made to the Product name or in the Uses, Dosage/administration, Contraindications, warnings, etc, Legal category, Authorisation number or Supplier sections have been marked as follows to highlight the alteration(s). A large blue diamond has been added after the product name and a smaller version of the same symbol (◊) has been inserted in front of the section heading(s) to indicate in which section(s) changes have been made. Where the product name itself has been altered, the small blue diamond has been added in front of the name. It should be noted that non-important changes in the Uses, Dosage/administration and Contra-indications, warnings, etc sections and all changes in other sections (except the Product name, Legal category, Authorisation number or Supplier) have not led to the product being marked as amended. Every effort has been made to ensure all products which have been significantly altered have been marked, however, no guarantee can be offered that this has been achieved and users of the Handbook are advised to diligently check all products they use. Where new products have been introduced into the Handbook, the word new has been added after the product name. In addition, an index has been included showing new and deleted products and those marked as having been amended. In all cases, the comparison made is with the previous year’s edition of the Handbook. Therefore, products marked as new may not be newly available, but are products appearing in this edition of the Handbook which did not appear in the previous edition. Similarly, products appearing in the index under Deleted may continue to be available but do not appear in this edition, having featured in the previous one. Whilst this edition remains current (until January 2010), when product suppliers wish to publicise significant changes to additives included in the book, amended pages will be posted

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on the Handbook Update website for free download. Be sure to visit the page below on a regular basis, or register to be informed when updates are available at: www.simonmounsey.com/hbupdate.htm.

Handbook of FEED ADDITIVES

2009

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Handbook of Feed Additives 2009 Handbook of Feed Additives 2009 is one of several directories, periodicals and reports published by Simon Mounsey Ltd. Amongst our other titles for feed producers and their suppliers are: • Feed Statistics 2009 • Feed Businesses 2009 • Feed Industry Review Details about these and other publications and services can be found on our website at: www.simonmounsey.com

Updates to this Handbook can also be found on the same website. You can go directly to the updates site at the following address: www.simonmounsey.com/hbupdate.htm

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Acid Buf Presentation

Free-flowing grey to off-white powder.

Use

Acid Buf is a natural buffer for use in all types of ruminant feed.

Acid Buf is non-hygroscopic and causes no pelleting problems.

Dosage/administration

Dairy:

50-80g/head/day.

Beef:

25-50g/head/day.

Sheep/Goats:

5-10g/head/day.

Horses:

25-50g/head/day.

Package sizes

25kg multi-layer valve closing paper bags.

1000kg bulk bags.

Further information

Withdrawal period: None.

Acid Buf has organic status.

Stability and storage 24 months when stored in a cool, dry place.

Safety and purity Acid Buf does not contain any organic or animal material. It is produced from sea-based minerals only.

Handling Avoid formation of dust.

If Acid Buf is used to replace sodium bicarbonate, it is important to ensure adequate sodium levels in diet.

Legal category

Buffer

EU authorisation

No 11.03 (minerals)

Supplier

AB Vista™ 3 Woodstock Court Blenheim Road Marlborough Business Park Marlborough Wiltshire SN8 4AN United Kingdom

Telephone: Fax: Email: Website:

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+44 (0)1672 517650 +44 (0)1672 517660 info@ab-vista.com www.ab-vista.com

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Acidomatrix™ Swine Presentation

new

ACIDOMATRIX™ SWINE is an energy rich complementary feed for swine with preservatives and a unique flavouring complex. The product comprises vegetable fat, distilled fatty acids from coconut/palmkernel oil, preservative premix and a flavouring complex.

Colour Structure Flowability Nutrients Preservatives

cream granulated ≤ 3 (Novus PN-Flow-02) Crude protein 0.0% Crude fat 49.5% Crude fibre 0.0% Crude ash 7.5% Lysine 0.0% Calcium 7.5% Phosphorous 0.0% Metabolizable Energy (ME) 25.4MJ/kg Formic acid, sorbic acid, calcium formate, calcium sorbate

Use

ACIDOMATRIX™ SWINE provides energy partly in form of highly digestible fatty acids of medium chain length. In addition the product has a strong antibacterial preservative effect. Furthermore ACIDOMATRIX™ SWINE stabilizes the intestinal microflora of monogastric animals, thereby ensuring animal health and performance. The marked inhibitory effects of ACIDOMATRIX™ SWINE on potentially pathogenic bacteria originate from the concerted action of the used preservative combination.

Dosage/administration

Piglet feed Grower/finisher feed Sow feed (peripartal period)

Precautions

Keep packages tightly closed. Avoid contact with eyes and mucous membranes. Upon contact irrigate thoroughly with water and seek medical advice if necessary. Follow instructions on the material safety data sheet.

Storage

A minimum shelf life of 12 months as from date of manufacture can be achieved if the product is stored in original sealed bags under cool and dry conditions.

Package sizes Legal category

Big Bag with polyethylene liner: 1,000kg net Paper-polyethylene bag: 25kg net Complementary feed

8

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up to 0.4% up to 0.2% up to 0.4%

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Supplier

Novus Europe SA/NV Avenue Marcel Thiry 200 1200 Brussels Belgium

Telephone: Fax: Email: Website:

UK Contact

Dr Helen Stebbens Quarry Cottage Easton Wells Somerset BA5 1EE

Tel/Fax: Email:

™ACIDOMATRIX is a trademark of Novus International, Inc.

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+32 2 778 1411 +32 2 771 8287 info.europe@novusint.com www.novusint.com

+44 1749 870862 helen.stebbens@novusint.com

9

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Acidomix® AFG Forte Presentation

new

ACIDOMIX® AFG Forte is a microgranulated nutritional feed supplement based on a combination of fatty acids distilled from coconut/palmkernel oil and feed preservatives such as formic acid (E-236), propionic acid (E-280) ammonium formate (E-295) and ammonium propionate (E-284) adsorbed to a silica carrier (E-551a).

Colour Structure Odour Particle size Flowability Active substances Analysis

white microgranulated slightly aromatic of formic and propionic acid and NH3 >0.8mm max. 5% (DIN 66165) ≤3 (Novus PN-Flow-02) Formic acid 218,000mg/kg Ammonium formate 160,000mg/kg Propionic acid 130,000mg/kg Ammonium propionate 38,000mg/kg Formic acid (HPLC) 335,000mg/kg1 Propionic acid (HPLC) 161,000mg/kg1 Ammonia (Kjeldahl) 50,000mg/kg1

Use

Due to strong antimicrobial effects, ACIDOMIX® AFG Forte improves feed hygiene. In addition the product provides highly digestible fatty acids to improve the energy supply of animals especially in phases of malabsorption. The inclusion of ACIDOMIX® AFG Forte in feed for rearing animals results in the stabilization of the gastro-intestinal microflora. Furthermore, the digestion of protein (activation of enzymes) is stimulated by lowering pH and acid-binding capacity of the feed. The use of ACIDOMIX® AFG Forte is a preventive measure in the control of salmonella.

Dosage/administration

Feed for young animals (especially piglets) up to 1.0% Poultry feed (salmonella control) up to 0.6%

Precautions

Keep packages tightly closed. Open with care. Follow instructions on the material safety data sheet.

Storage

A minimum shelf life of 12 months as from date of manufacture can be achieved if the product is stored in original sealed bags under cool and dry conditions. Protect from freezing.

Package sizes

Big Bag with polyethylene liner: 1,000kg net Paper-polyethylene bag: 10kg or 25kg net

Legal category

Nutritional feed supplement

10

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Supplier

Novus Europe SA/NV Avenue Marcel Thiry 200 1200 Brussels Belgium

Telephone: Fax: Email: Website:

UK Contact

Dr Helen Stebbens Quarry Cottage Easton Wells Somerset BA5 1EE

Tel/Fax: Email:

1

®Acidomix is a registered trademark of Novus Deutschland GmbH

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+32 2 778 1411 +32 2 771 8287 info.europe@novusint.com www.novusint.com

+44 1749 870862 helen.stebbens@novusint.com

Tolerance in compliance with German Feed Directive, §19

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Acidomix® AFL Presentation

new

ACIDOMIX® AFL is a feed acidifier based on formic acid (E236), propionic acid (E-280), ammonium formate (E-295) and ammonium propionate (E-284).

Colour Structure Odour Active substances Analysis

colourless - yellowish liquid weakly aromatic Formic acid Ammonium formate Propionic acid Ammonium propionate Formic acid (HPLC) Propionic acid (HPLC) Ammonia (Kjeldahl)

310,000mg/kg 260,000mg/kg 191,000mg/kg 60,000mg/kg 500,000mg/kg1 240,000mg/kg1 81,000mg/kg1

Use

Due to strong antimicrobial effects, ACIDOMIX® AFL improves feed hygiene. The inclusion of ACIDOMIX® AFL in feed for rearing animals results in the stabilization of the gastro-intestinal micro-flora. Furthermore, the digestion of protein (activation of enzymes) is stimulated by lowering pH and acid-binding capacity of the feed. Acidification of the drinking water by ACIDOMIX® AFL markedly reduces its microbial load. The use of ACIDOMIX® AFL is a preventative measure to control salmonella.

Dosage/administration

Piglet feed Acidification of drinking water Stabilization of compound feed Salmonella control Poultry feed

Precautions

Keep packages tightly closed. Open with care. Follow instructions on the material safety data sheet.

Storage

A minimum shelf life of 24 months as from date of manufacture can be achieved if the product is stored in original sealed packaging under cool and dry conditions.

Package sizes

Bulk: IBC – 1,000kg net; Drum – 200kg net; Pail – 30kg net.

Legal category

Premixture

12

Product Section 2009.indd 12

up to 0.8% up to 0.2% up to 0.4% up to 0.6% up to 0.4%

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Supplier

Novus Europe SA/NV Avenue Marcel Thiry 200 1200 Brussels Belgium

Telephone: Fax: Email: Website:

UK Contact

Dr Helen Stebbens Quarry Cottage Easton Wells Somerset BA5 1EE

+32 2 778 1411 +32 2 771 8287 info.europe@novusint.com www.novusint.com

Tel/Fax: Email:

1

®Acidomix is a registered trademark of Novus Deutschland GmbH

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+44 1749 870862 helen.stebbens@novusint.com

Tolerance in compliance with German Feed Directive, §19

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Acidomix® Protect Presentation

new

ACIDOMIX® PROTECT is a dustless, granulated preservative premix containing formic acid (E-236), sorbic acid (E-200) and fumaric acid (E-297) as well as their salts.

Colour Structure Flowability Analysis

white granulated ≤3 (Novus PN-Flow-02) formic acid (HPLC) 250,000mg/kg1 sorbic acid (HPLC) 100,000mg/kg1 fumaric acid (HPLC) 100,000mg/kg1

Use

In addition to its preserving effects, ACIDOMIX® PROTECT stabilizes the intestinal microflora of monogastric animals, thereby ensuring animal health and performance. The marked inhibitory effects of ACIDOMIX® PROTECT on potentially pathogenic bacteria originate from the concerted action of the used preservatives formic, sorbic and fumaric acids.

Dosage/administration

Piglet feed Grower/finisher feed Sow feed (peripartal period) Poultry feed

Precautions

Keep packages tightly closed. Open with care. Follow instructions on the material safety data sheet.

Storage

A minimum shelf life of 12 months as from date of manufacture can be achieved if the product is stored in original sealed bags under cool and dry conditions.

Package sizes

Big Bag with polyethylene liner: 1,000kg net paper-polyethylene bag: 25kg net

Legal category

Premix

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up to 0.4% up to 0.2% up to 0.4% up to 0.3%

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Supplier

Novus Europe SA/NV Avenue Marcel Thiry 200 1200 Brussels Belgium

Telephone: Fax: Email: Website:

UK Contact

Dr Helen Stebbens Quarry Cottage Easton Wells Somerset BA5 1EE

+32 2 778 1411 +32 2 771 8287 info.europe@novusint.com www.novusint.com

Tel/Fax: Email:

1

®Acidomix is a registered trademark of Novus Deutschland GmbH

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+44 1749 870862 helen.stebbens@novusint.com

Tolerance in compliance with German Feed Directive, §19

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Activate® WD Max

new

Presentation

ACTIVATE® WD Max is a pre-mixture of liquid organic acids including HMTBa. ACTIVATE® WD Max is not only a source of methionine; it can also be used as a preservative for use in drinking water. The product comprises:

• Methionine Hydroxy Analogue (HMTBa)

• Formic acid

• Propionic acid

Total acid:

89%

HMTBa:

35%

Appearance:

Liquid, amber colour

Density @25°C:

1.16kg/l

pH @ 1% aqueous solution:

2.35

ME Poultry:

DE Swine:

2811kCal

Protein Value:

208g/kg

Available methionine value:

350g/kg

Use

To improve the hygiene status of drinking water and to control pathogens.

Nutritional effect thanks to the supply of a sulphur amino acid source.

Dosage/administration

0.5-1.0ml/litre in drinking water

Dose may vary according to the water hardness – to reach an optimal pH = 3.5-4.0

For poultry, swine, rabbits

Ask your technician and control the water intake carefully

Precautions

Protect from freezing. Store in sealed packaging under dry and cool conditions. Corrosive acid product, causes burns. For handling refer to Material Safety Data Sheet.

Package sizes

Pail: 30kg; Drum: 230kg; IBC: 1000kg

2700kCal

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Supplier

Novus Europe SA/NV Avenue Marcel Thiry 200 1200 Brussels Belgium

Telephone: Fax: Email: Website:

UK Contact

Dr Helen Stebbens Quarry Cottage Easton Wells Somerset BA5 1EE

+32 2 778 1411 +32 2 771 8287 info.europe@novusint.com www.novusint.com

Tel/Fax: Email:

速ACTIVATE is a trademark of Novus International, Inc. and is registered in the United States and other countries.

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+44 1749 870862 helen.stebbens@novusint.com

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Aivlosin速 8.5mg/g Oral Powder for Pigs

new

Presentation

Aivlosin速 8.5mg/g Oral Powder for Pigs contains tylvalosin 8.5mg/g (as tylvalosin tartrate).

Uses

Treatment and prevention of Swine Enzootic Pneumonia caused by susceptible strains of Mycoplasma hyopneumoniae. At the recommended dose, lung lesions and weight loss are reduced but infection with Mycoplasma hyopneumoniae is not eliminated.

Treatment of Porcine Proliferative Enteropathy (ileitis) caused by Lawsonia intracellularis.

Treatment of clinical outbreaks of Swine Dysentery in herds, caused by Brachyspira hyodysenteriae, where the disease has been diagnosed, and prevention of further clinical cases.

Dosage/administration

For oral use. For use in individual pigs on farms where only a small number of pigs are to receive the medicine. Larger groups should be treated with medicated feeding stuff containing the premix.

For treatment and prevention of Swine Enzootic Pneumonia The dosage is 2.125 mg tylvalosin per kg bodyweight per day in-feed for seven consecutive days. Secondary infection by organisms such as Pasteurella multocida and Actinobacillus pleuropneumoniae may complicate enzootic pneumonia and require specific medication.

For treatment of Porcine Proliferative Enteropathy (ileitis) The dosage is 4.25 mg tylvalosin per kg bodyweight per day for ten consecutive days.

For treatment and prevention of Swine Dysentery The dosage is 4.25 mg tylvalosin per kg bodyweight per day for ten consecutive days. This is achieved by thoroughly mixing Aivlosin速 8.5mg/g Oral Powder for Pigs into the daily ration for each individual pig. Scoops of three sizes are provided for measuring the correct amount of Aivlosin速 8.5mg/g Oral Powder for Pigs for mixing with the daily ration, according to the schedule below. The feed containing the oral powder should be provided as the sole ration for the periods recommended above.

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The pig to be treated should be weighed and the amount of feed that the pig is likely to consume should be estimated, based on a daily feed intake equivalent to 5% of bodyweight. Consideration must be given to pigs whose daily feed intake is reduced or restricted. The correct quantity of Aivlosin® 8.5mg/g Oral Powder should then be added to the estimated quantity of daily ration for each pig, in a bucket or similar receptacle, and thoroughly mixed. The product should only be added to dry non-pelleted feed. Swine Enzootic Pneumonia – 2.125mg/kg bodyweight Bodyweight range (kg)

Scoop size*

Number of scoops

6.5-12

5ml

1

13-24

10ml

1

25-48

10ml

2

49-72

10ml

3

73-96

10ml

4

97-120

10ml

5

121-144

10ml

6

145-168

10ml

7

169-192

10ml

8

* A level scoop of the product should be measured

PPE (Ileitis) and Swine Dysentery – 4.25mg/kg bodyweight Bodyweight range (kg)

Scoop size*

Number of scoops

6.5-12

5ml

1

13-24

10ml

2

25-48

10ml

4

49-72

10ml

6

73-96

10ml

8

97-115

25ml

4

116-145

25ml

5

146-175

25ml

6

176-200

25ml

7

* A level scoop of the product should be measured

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Acute cases and severely diseased pigs with reduced food or water intake should be treated with a suitable injectable product. In addition to medical treatment, good management and hygiene practices should be established on the farm in order to reduce the risk of infection and to control the potential development of resistance.

Contra-indications, warnings, etc.

Contra-indications None.

Withdrawal Period Meat and offal: Two days.

Operator Warnings Because Aivlosin速 has been shown to cause hypersensitivity reactions in laboratory animals people with known hypersensitivity to tylvalosin tartrate should avoid any contact with the product. When adding the veterinary medicinal product to the individual feed ration and when handling this feed, direct contact with eyes, skin and mucous membranes should be avoided. Personal protective equipment should be worn when handling the veterinary medicinal product or the feed with product added: overalls, impervious gloves and either a disposable half-mask respirator conforming to European Standard EN149 or a nondisposable respirator conforming to European Standard EN140, with a filter to European Standard EN143. Wash contaminated skin.

In case of accidental ingestion seek medical advice immediately and show the label to the physician.

General Precautions For animal treatment only.

Further Information The safety of Aivlosin速 during pregnancy and lactation has not been established in pigs. Use only in accordance with risk/ benefit assessment by the responsible veterinarian. Studies in laboratory animals have not produced any evidence of teratogenicity. Maternal toxicity in rodents has been observed at doses of 400mg tylvalosin per kg bodyweight and above. In mice, a slight reduction in the foetal bodyweight was seen at doses causing maternal toxicity.

Cross-resistance between tylvalosin and other macrolide antibiotics cannot be excluded.

Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements.

For any information about this veterinary medicinal product, please contact the marketing authorisation holder.

Not all pack sizes may be marketed.

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Pharmaceutical precautions

Do not store above 25째C.

Store in the original container.

Keep out of reach and sight of children.

Do not use after the expiry date stated on the label.

Feed to which the oral powder has been added should be replaced if not consumed within 24 hours.

Legal category

POM-V

Package quantities

1kg and 3kg in polyethylene lined paper bags.

EU authorisation number

EU/2/04/044/005-006

Marketing authorisation holder:

ECO Animal Health Ltd 78 Coombe Road New Malden Surrey KT3 4QS

Keep the container tightly closed.

Tel: Fax: E-mail: Web:

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020 8447 8899 020 8447 9292 enquiries@ecoanimalhealth.com www.ecoanimalhealth.com

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Aivlosin速 8.5mg/g Premix Presentation

Aivlosin速 8.5mg/g premix for medicated feeding stuff for pigs contains tylvalosin 8.5mg/g (as tylvalosin tartrate).

Uses

Treatment and prevention of Swine Enzootic Pneumonia caused by susceptible strains of Mycoplasma hyopneumoniae. At the recommended dose, lung lesions and weight loss are reduced but infection with Mycoplasma hyopneumoniae is not eliminated.

Treatment of Porcine Proliferative Enteropathy (ileitis) caused by Lawsonia intracellularis in herds where there is a diagnosis based on clinical history, post-mortem findings and clinical pathology results.

Treatment of clinical outbreaks of Swine Dysentery in herds, caused by Brachyspira hyodysenteriae, where the disease has been diagnosed, and prevention of further clinical cases.

Dosage/administration

In-feed use. for incorporation into dry feed only.

For treatment and prevention of Swine Enzootic Pneumonia The dosage is 2.125 mg tylvalosin per kg bodyweight per day in-feed for seven consecutive days. Secondary infection by organisms such as Pasteurella multocida and Actinobacillus pleuropneumoniae may complicate enzootic pneumonia and require specific medication.

For treatment of Porcine Proliferative Enteropathy (ileitis) The dosage is 4.25 mg tylvalosin per kg bodyweight per day for ten consecutive days.

For treatment and prevention of Swine Dysentery The dosage is 4.25 mg tylvalosin per kg bodyweight per day for ten consecutive days.

Indication

Daily dose of active ingredient (mg/kg bodyweight)

Duration of treatment

In feed inclusion rate (Aivlosin速 8.5mg/g Premix)

Treatment and prevention of swine enzootic pneumonia

2.125

7 days

5kg/tonne*

Treatment of PPE (ileitis)

4.250

10 days

10kg/tonne*

Treatment and prevention of swine dysentery

4.250

10 days

10kg/tonne*

* Important: these inclusion rates assume a pig eats equivalent of 5% bodyweight per day.

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In older pigs, or in pigs with reduced appetite, or on restricted feed intake, inclusion levels may need to be increased to achieve target dosage. Where feed intake is reduced, use the following formula:

kg Premix/tonne feed =

Dose rate (mg/kg bodyweight) x bodyweight (kg)

Daily feed intake (kg) x Premix strength (mg/g).

Acute cases and severely diseased pigs with reduced food or water intake should be treated with a suitable injectable product.

In addition to medical treatment, good management and hygiene practices should be established on the farm in order to reduce the risk of infection and to control the build up of resistance.

The medicated feed should be fed as the sole ration.

Mixing Instructions A horizontal ribbon mixer should be used to incorporate the product into feeding stuff. It is recommended that Aivlosin® is first mixed with 10kg of the feeding stuff, followed by the rest of the feeding stuff and mixed well. Medicated feed may then be pelleted. Pelleting conditions involve a single pre-conditioning step with steam for five minutes and pelleting at not more than 70°C under normal conditions.

No known incompatibilities.

Contra-indications, warnings, etc.

Contra-indications None.

Withdrawal Period Meat and offal: Two days.

Operator Warnings Because Aivlosin® has been shown to cause hypersensitivity reactions in laboratory animals people with known hypersensitivity to tylvalosin tartrate should avoid any contact with the product.

When mixing the veterinary medicinal product and handling the medicated feed, direct contact with eyes, skin and mucous membranes should be avoided. Personal protective equipment should be worn when mixing the veterinary medicinal product or handling the medicated feed: overalls, impervious gloves and either a disposable half-mask respirator conforming to European Standard EN149 or a non-disposable respirator conforming to European Standard EN140, with a filter to European Standard EN143. Wash contaminated skin.

In case of accidental ingestion seek medical advice immediately and show the label to the physician.

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General Precautions For animal treatment only.

Further Information The safety of AivlosinÂŽ during pregnancy and lactation has not been established in pigs. Use only in accordance with risk/ benefit assessment by the responsible veterinarian. Studies in laboratory animals have not produced any evidence of teratogenicity. Maternal toxicity in rodents has been observed at doses of 400mg tylvalosin per kg bodyweight and above. In mice, a slight reduction in the foetal bodyweight was seen at doses causing maternal toxicity.

Generally, strains of Brachyspira hyodysenteriae have higher MIC values in cases of resistance against other macrolides, such as tylosin. The clinical relevance of this reduced susceptibility is not fully explored. Cross-resistance between tylvalosin and other macrolides cannot be excluded.

Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements.

Consideration should be given to official guidance on the incorporation of medicated premixes in final feed.

For any information about this veterinary medicinal product, please contact the marketing authorisation holder.

Not all pack sizes may be marketed.

Pharmaceutical precautions

Keep out of the reach and sight of children.

Keep the container tightly closed.

Store in the original container.

Do not use after the expiry date stated on the label.

Keep out of reach and sight of children.

Do not use after the expiry date stated on the label.

Shelf life after incorporation into meal: one month; or pelleted feed: two weeks.

Legal category

POM-V

Package quantities

5kg, 20kg bags

EU authorisation number

EU/2/04/044/003-004

Do not store above 25°C.

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Marketing authorisation holder:

ECO Animal Health Ltd 78 Coombe Road New Malden Surrey KT3 4QS Tel: Fax: E-mail: Web:

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020 8447 8899 020 8447 9292 sales@ecoanimalhealth.com www.ecoanimalhealth.com

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Aivlosin速 42.5mg/g Premix Presentation

Aivlosin速 42.5mg/g premix for medicated feeding stuff for pigs contains tylvalosin 42.5mg/g (as tylvalosin tartrate)

Uses

Treatment and prevention of Swine Enzootic Pneumonia caused by susceptible strains of Mycoplasma hyopneumoniae. At the recommended dose, lung lesions and weight loss are reduced but infection with Mycoplasma hyopneumoniae is not eliminated.

Treatment of Porcine Proliferative Enteropathy (ileitis) caused by Lawsonia intracellularis in herds where there is a diagnosis based on clinical history, post-mortem findings and clinical pathology results.

Treatment of clinical outbreaks of Swine Dysentery in herds, caused by Brachyspira hyodysenteriae, where the disease has been diagnosed, and prevention of further clinical cases.

Dosage/administration

In-feed use. for incorporation into dry feed only.

For treatment and prevention of Swine Enzootic Pneumonia The dosage is 2.125 mg tylvalosin per kg bodyweight per day in-feed for seven consecutive days. Secondary infection by organisms such as Pasteurella multocida and Actinobacillus pleuropneumoniae may complicate enzootic pneumonia and require specific medication.

For treatment of Porcine Proliferative Enteropathy (ileitis) The dosage is 4.25 mg tylvalosin per kg bodyweight per day for ten consecutive days.

For treatment and prevention of Swine Dysentery The dosage is 4.25 mg tylvalosin per kg bodyweight per day for ten consecutive days.

Indication

Daily dose of active ingredient (mg/kg bodyweight)

Duration of treatment

In feed inclusion rate (Aivlosin速 42.5mg/g Premix)

Treatment and prevention of swine enzootic pneumonia

2.125

7 days

1kg/tonne*

Treatment of PPE (ileitis)

4.250

10 days

2kg/tonne*

Treatment and prevention of swine dysentery

4.250

10 days

2kg/tonne*

* Important: these inclusion rates assume a pig eats equivalent of 5% bodyweight per day.

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In older pigs, or in pigs with reduced appetite, or on restricted feed intake, inclusion levels may need to be increased to achieve target dosage. Where feed intake is reduced, use the following formula:

kg Premix/tonne feed =

Dose rate (mg/kg bodyweight) x bodyweight (kg)

Daily feed intake (kg) x Premix strength (mg/g).

Acute cases and severely diseased pigs with reduced food or water intake should be treated with a suitable injectable product.

In addition to medical treatment, good management and hygiene practices should be established on the farm in order to reduce the risk of infection and to control the build up of resistance.

The medicated feed should be fed as the sole ration.

Mixing Instructions A horizontal ribbon mixer should be used to incorporate the product into feeding stuff. It is recommended that Aivlosin® is first mixed with 10kg of the feeding stuff, followed by the rest of the feeding stuff and mixed well. Medicated feed may then be pelleted. Pelleting conditions involve a single pre-conditioning step with steam for five minutes and pelleting at not more than 70°C under normal conditions.

No known incompatibilities.

Contra-indications, warnings, etc.

Contra-indications None.

Withdrawal Period Meat and offal: Two days.

Operator Warnings Because Aivlosin® has been shown to cause hypersensitivity reactions in laboratory animals people with known hypersensitivity to tylvalosin tartrate should avoid any contact with the product.

When mixing the veterinary medicinal product and handling the medicated feed, direct contact with eyes, skin and mucous membranes should be avoided. Personal protective equipment should be worn when mixing the veterinary medicinal product or handling the medicated feed: overalls, impervious gloves and either a disposable half-mask respirator conforming to European Standard EN149 or a non-disposable respirator conforming to European Standard EN140, with a filter to European Standard EN143. Wash contaminated skin.

In case of accidental ingestion seek medical advice immediately and show the label to the physician.

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General Precautions For animal treatment only.

Further Information The safety of AivlosinÂŽ during pregnancy and lactation has not been established in pigs. Use only in accordance with risk/ benefit assessment by the responsible veterinarian. Studies in laboratory animals have not produced any evidence of teratogenicity. Maternal toxicity in rodents has been observed at doses of 400mg tylvalosin per kg bodyweight and above. In mice, a slight reduction in the foetal bodyweight was seen at doses causing maternal toxicity.

Generally, strains of Brachyspira hyodysenteriae have higher MIC values in cases of resistance against other macrolides, such as tylosin. The clinical relevance of this reduced susceptibility is not fully explored. Cross-resistance between tylvalosin and other macrolides cannot be excluded.

Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements.

Consideration should be given to official guidance on the incorporation of medicated premixes in final feed.

For any information about this veterinary medicinal product, please contact the marketing authorisation holder.

Not all pack sizes may be marketed.

Pharmaceutical precautions

Keep out of the reach and sight of children.

Keep the container tightly closed.

Store in the original container.

Do not use after the expiry date stated on the label.

Keep out of reach and sight of children.

Do not use after the expiry date stated on the label.

Shelf life after incorporation into meal: one month; or pelleted feed: two weeks.

Legal category

POM-V

Package quantities

5kg, 20kg bags

EU authorisation number

EU/2/04/044/001-002

Do not store above 25°C.

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Marketing authorisation holder:

ECO Animal Health Ltd 78 Coombe Road New Malden Surrey KT3 4QS Tel: Fax: E-mail: Web:

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020 8447 8899 020 8447 9292 sales@ecoanimalhealth.com www.ecoanimalhealth.com

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Aivlosin速 625mg/g Granules for Use in Drinking Water for Chickens new Presentation

Aivlosin速 625mg/g Granules for Use in Drinking Water for Chickens contains tylvalosin 625mg/g (as tylvalosin tartrate).

Uses

Aivlosin速 625 mg/g Granules for Use in Drinking Water for Chickens is indicated for treatment and prevention of respiratory disease associated with Mycoplasma gallisepticum in chickens.

As an aid in the prevention strategy to reduce the clinical signs and mortality from respiratory disease in flocks, where infection in ovum with Mycoplasma gallisepticum is likely because the disease is known to exist in the parent generation. The prevention strategy should include efforts to eliminate the infection from the parent generation.

Dosage/administration

For use in drinking water.

For treatment of respiratory disease associated with Mycoplasma gallisepticum The dosage is 25mg tylvalosin per kg bodyweight per day in drinking water for three consecutive days.

When used as an aid in the prevention strategy (where infection in ovum with Mycoplasma gallisepticum is likely): The dosage is 25mg tylvalosin per kg bodyweight per day in drinking water for three consecutive days at one day old. This is followed by a second treatment with 25mg tylvalosin per kg bodyweight per day in drinking water for three consecutive days at the period of risk, i.e. at times of management stress such as administration of vaccines (typically when birds are 2-3 weeks old).

Determine the combined bodyweight (in kg) of all the chickens to be treated. Select the correct number of sachets according to the amount of product required. One sachet of 40g is sufficient for a total of 1000kg of chickens (e.g. 20,000 birds with an average bodyweight of 50g). In order to achieve a correct dose, the preparation of a concentrated (stock) solution might be required (e.g. to treat a total of 500kg total bird weight, only 50% of the prepared stock solution should be used).

The product should be added to a volume of water that the chickens will consume in one day. No other source of drinking water should be available during the medication period.

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The product may be mixed directly into the drinking water system or first mixed as a stock solution into a smaller amount of water, which is then added into the drinking water system.

When mixing the product directly into the drinking water system, the contents of the sachet should be sprinkled onto the surface of the water and mixed thoroughly until a clear solution is produced (usually within three minutes).

When preparing a stock solution the maximum concentration should be one sachet per 1,500ml and it is necessary to mix the solution for ten minutes. After this time, any remaining cloudiness will not affect efficacy of the product.

Contra-indications, warnings, etc.

Contra-indications None

Not authorised for use in laying birds producing eggs for human consumption. Do not use within 14 days of the onset of laying.

Operator Warnings Because Aivlosin速 has been shown to cause hypersensitivity reactions in laboratory animals people with known hypersensitivity to tylvalosin tartrate should avoid any contact with the product. When mixing the veterinary medicinal product and handling the medicated water, direct contact with eyes, skin and mucous membranes should be avoided. Personal protective equipment should be worn when handling the veterinary medicinal product or water with product added: overalls, impervious gloves and either a disposable half-mask respirator conforming to European Standard EN149 or a non-disposable respirator conforming to European Standard EN140, with a filter to European Standard EN143. Wash contaminated skin.

In case of accidental ingestion seek medical advice immediately and show the label to the physician.

General Precautions For animal treatment only.

Further Information Good management and hygiene practices should be introduced in order to reduce the risk of re-infection.

Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements.

For any information about this veterinary medicinal product, please contact the marketing authorisation holder.

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Withdrawal Period Meat and offal: Two days.

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Pharmaceutical precautions

Do not store above 30째C.

Do not use after the expiry date stated on the label.

Opened sachets should not be stored.

Shelf-life of the medicated drinking water: 24 hours

Only a sufficient amount of medicated drinking water should be prepared to cover the daily requirements.

Medicated drinking water should be replaced every 24 hours.

Legal category

POM-V

Package quantities

40g sachets.

EU authorisation number

EU/2/04/044/007

Marketing authorisation holder:

ECO Animal Health Ltd 78 Coombe Road New Malden Surrey KT3 4QS

Keep out of reach and sight of children.

Tel: Fax: E-mail: Web:

020 8447 8899 020 8447 9292 enquiries@ecoanimalhealth.com www.ecoanimalhealth.com

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ALKOSEL® R397 Presentation

ALKOSEL® R397 is an inactivated whole cell yeast product (Saccharomyces cerevisiae R397) containing naturally elevated levels of organic selenium. ALKOSEL® R397 contains 2000 ppm of selenium.

Uses

Natural alternative to sodium selenite, ALKOSEL® R397 is a highly bioavailable source of selenium. It is the same natural form of selenium as found in plants and cereals. Compared to inorganic selenium, Selenium in ALKOSEL® R397 is better absorbed by the animal in a useful form and is considerably safer. Selenium is an essential trace element involved in many metabolic pathways such as reproduction, immunity, antioxidation. Many animal species benefit from the inclusion of ALKOSEL® R397 in their diet from pigs, poultry and ruminants to pets and fish.

Dosage/administration

ALKOSEL® R397 is a source of selenium to be included in compound feed and/or mineral premixes. In the EU, when used as the sole source of added selenium, do not exceed 250g/tonne of finished feed as this equals 0.5 ppm Se supplementation. Follow PDS recommendations.

Warnings

To be used exclusively in the manufacture of feedingstuffs for selenium supplementation purposes. In the EU, total selenium in feed material from all sources must not exceed 0.5 ppm. The addition to feed of higher levels of this premix containing selenium is not permitted. Follow MSDS for specific handling recommendations.

Legislation

ALKOSEL® R397 is a nutritional feed additive authorised in the EU for use in all animal species. EC No 3b8.11.

Precautions

ALKOSEL® R397 should be stored in a cool and dry place. Shelf life of 24 months.

Packaging

ALKOSEL® R397 is available in 25kg bags in a polyethylene liner.

Supplier

Lallemand Animal Nutrition Collivaud House Ocean Way Cardiff CF24 5PD

Tel: Fax: Email:

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029 2047 5561 029 2047 5598 lhurdidge@lallemand.com

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Keep this Handbook up-to-date! When this Handbook was published, in February 2009, everything possible had been done by the publisher and product suppliers to ensure the information contained was accurate and up-to-date. Inevitably, some products will be subject to important changes between publication of this edition and the next. Whenever we are notified of changes to product information contained in this edition, these changes will be posted on our website at: www.simonmounsey.com/hbupdate.htm The updates will be in the form of replacement pages which can be printed out and used to replace pages in the original. As an additional service to users of this book, you may register to receive notification whenever an updated page is posted. Simply send an email to mail@simonmounsey.com with the subject line “Handbook Updates 2009� and your email address for notification.

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Alphamune™ G Presentation

A light-brown, granular feed ingredient for pigs and poultry containing a unique combination of two natural ingredients derived from brewers’ yeast: β-glucans (1-3, 1-6) and mannans.

Uses

Alphamune™ G can be used as a source of oligosaccharides for animal feed application. β-glucans have been proven to enhance the immune system; mannans have a prebiotic effect by binding to intestinal bacterial pathogens and also act as a substrate to beneficial lactobacilli, thus improving the intestinal flora. Alphamune™ G is a reliable replacement for anti-microbial growth promoters in pigs and poultry.

Dosage/administration

Alphamune™ G is used at 500g per tonne of finished feed (sows: 1,500g per tonne of finished feed or 5g per sow per day).

Contra-indications, warnings, etc

For use in animal feed only.

Additional information

Alphamune™ G is a granulated feed ingredient manufactured with a unique High-Shear granulation technique. This makes it easy-flowable and thoroughly mixable into finished feeds.

Precautions

Alphamune™ G is not toxic. Avoid dust inhalation. Wash hands after use and before meals.

Storage

Storage under dry and cool conditions is recommended. Use within two years of manufacturing date.

Package quantities

20kg bag

Supplier

Alpharma (Belgium) BVBA Garden Square Laarstraat 16 B-2610 Antwerp Belgium Tel: Fax: Website:

+32 (0) 3 287 3880 +32 (0) 3 287 3881 www.alphamune.com

UK representative

Poultry

Tel: +44 (0) 7740 483818

Pigs

Tel: +44 (0) 7717 345108

Alphamune™ is a registered trade mark of Alpharma Inc, Bridgewater, USA

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Amasil NA

new

Presentation

A colourless liquid organic acid mixture, with characteristic slightly pungent odour, fully miscible in water at pH of 2.1 (at 100g/litre H2O).

Composition 75% formic acid 7% sodium 18% H2O

Uses

Amasil NA is buffered formic acid. Therefore it is classed as irritant. It is easier to handle and has a reduced odour compared to pure formic acid.

Based on its very high formic acid and sodium formate content, Amasil NA is an excellent preservative for inhibiting bacteria and yeasts in feedstuffs.

Amasil NA is effective in inhibiting micro-organisms such as Salmonella spp, E. coli and Campylobacter spp in compound feed or in single feed components.

Dosage/administration

Amasil NA should be added at the time of mixing the final feed. The following doses are recommended for inclusion of Amasil NA in the various stages of growth and types of stock:

Animal

Amasil NA inclusion (kg/tonne)

Pig creep/starter

6-10

Pig link

4-6

Pig grower/finisher

4-6

Sows

5-9

Broilers

3-4

Turkeys

4-6

Contra-indications/ precautions

For animal use only.

No withdrawal period required.

This acid mixture is corrosive. Only corrosive resistant materials must be used for storage and transport. Acid resistant gloves and tightly fitting goggles must be worn when handling this acid mixture.

In case of contact, immediately remove contaminated clothing and wash skin thoroughly with clean cold water.

Can be used through the whole life cycle.

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Legal category

Preservative.

Packaging sizes

1,000kg IBCs or 24,000kg bulk

Supplier

BASF Group PO Box 4 Earl Road Cheadle Hulme Cheshire SK8 6QG Tel: Fax: Website:

Contact

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0161 485 6222 0161 485 5487 www.animal-nutrition.basf.com

Brian Pope Telephone: 01772 603119 Email: brian.pope@basf.com

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Handbook of Feed Additives 2009 Handbook of Feed Additives 2009 is one of several directories, periodicals and reports published by Simon Mounsey Ltd. Amongst our other titles for feed producers and their suppliers are: • Feed Statistics 2009 • Feed Businesses 2009 • Feed Industry Review Details about these and other publications and services can be found on our website at: www.simonmounsey.com

Updates to this Handbook can also be found on the same website. You can go directly to the updates site at the following address: www.simonmounsey.com/hbupdate.htm

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AmmoMIN

new

Presentation

AmmoMIN is a clay mineral from the class of clinoptilolites of sedimentary origin – E568.

AmmoMIN is a natural crystalline-hydrated alumino-silicate.

Product information

Product composition Clinoptilolite: 80% (guaranteed minimum) Other clay minerals: 20% (maximum)

Appearance AmmoMIN is available in different granulometries: 0-200Îźm 0.2-0.5mm 0-1mm 0.5-1.0mm 1.0-2.5mm

Uses

AmmoMIN is a pellet binder. In addition, Clinoptilolites of sedimentary origin have been reported to bind water and ammonia in the gut when included in diets for pigs, poultry, ruminants and salmon. This may lead to better gut health, drier faeces and improved litter quality (depending on animal species).

Dosage/administration

Depends on animal species and purpose ranging from 0.5% to 2.0%.

Legal category

Category 1 (Annex I Reg 1831/2003)

Binders, anti-caking agents and coagulants

EU authorisation

E568

Storage

Shelf life: 2 years.

Package quantities

25kg bags, 1000kg big bags or bulk.

Supplier

Orffa Additives BV Vierlinghstraat 51 4251 LC Werkendam The Netherlands

Orffa UK Office PO Box 113 Northallerton North Yorkshire DL6 1YH

Tel: +31 (0) 183 44 77 44 Fax: +31 (0) 183 44 30 60 E-mail: info@orffa.com Website: www.orffa.com

Tel: +44 (0) 1609 772881 Fax: +44 (0) 1609 780941

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Apralan® G 200 Premix Presentation

Apralan G 200 Premix is a brown free-flowing granulated premix for inclusion in pig feeds. Each kg of premix contains apramycin sulphate equivalent to 200g apramycin activity.

Uses

For the treatment and control of bacterial enteritis in young pigs caused by Escherichia coli and other organisms susceptible to apramycin.

Dosage/administration

Incorporate the product at a rate of 0.5kg per tonne to give 100g apramycin per tonne of complete feed (100ppm) to provide 4-8mg apramycin/kg bodyweight. Feed as the only ration for a maximum period of 28 days.

Contra-indications, warnings, etc.

Operators should wash thoroughly with soap and water after handling. Toxic to cats. Do not use in known cases of hypersensitivity. Keep out of reach of children. Withdrawal period Pigs must not be slaughtered for human consumption during treatment. Pigs may be slaughtered for human consumption only after 14 days from the last treatment. Operator warnings Operators should wash thoroughly with soap and water after handling.

Pharmaceutical precautions

Store below 25°C in a dry place. The product can be incorporated into pelleted feed, preconditioned with steam for up to 15 minutes at a temperature not greater than 75°C. The product will remain stable in the finished feed and in pelleted feed for three months. To ensure thorough dispersion of the product it should first be mixed with a small quantity of feed (20-50kg) before incorporation in the final mix. The shelf life of the product is 24 months from the date of manufacture. General precautions For animal treatment only. Keep out of reach of children.

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Legal category

POM-V

Package quantities

Multi-walled paper sacks containing 5kg.

Marketing authorisation number

Vm 00006/4108.

Marketing authorisation holder

Elanco Animal Health Lilly House Priestley Road Basingstoke Hampshire RG24 9NL

Tel: Fax:

速Apralan is a registered trademark of Eli Lilly and Company Ltd.

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(01256) 353131 (01256) 779510

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Aurofac速 100 Granular Presentation

A yellow to dark yellow granular premix containing 100g chlortetracycline hydrochloride per kg.

Uses

For oral administration as an aid in the treatment of respiratory and systemic infections associated with chlortetracycline-sensitive organisms in chickens, pigs, turkeys and ducks.

Dosage/administration

Recommended doses of chlortetracycline hydrochloride are for: Pigs: 10-20mg/kg bodyweight daily Layers: 20-25mg/kg bodyweight daily Broilers: 20-30mg/kg bodyweight daily Turkeys: 10-30mg/kg bodyweight daily Ducks: 10-30mg/kg bodyweight daily For average doses the recommended mixing rate is 3kg of Aurofac速 100 Granular per tonne to supply 300g chlortetracycline hydrochloride per tonne of complete feed. However, the correct incorporation rate should always be calculated based on the feed consumption rates of the animals to be treated. Treatment is recommended for 5-7 days. During treatment supply Aurofac速 100 Granular medicated feed only.

Contra-indications, warnings, etc.

Use in adult ruminants is not recommended. Withdrawal period: Animals must not be slaughtered for human consumption during treatment. Animals may be slaughtered for human consumption only after the following numbers of days from the end of treatment: Pigs: Chickens: Turkeys: Ducks:

10 days 2 days 2 days 4 days

Eggs from medicated laying birds may not be used for human consumption up to four days after treatment.

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Pharmaceutical precautions

Do not store above 30°C. Close the bag securely after use. Store apart from animal feedstuffs. The product will remain stable for 36 months in unopened bags. In final mash feed, the product will remain stable for two months and in final pelleted feed for three weeks. Open bags of premix should be used within 14 days. Dispose of any unused product and empty containers in accordance with guidance from your local waste regulation authority.

General precautions

Chlortetracycline is of low toxicity and side effects are rarely encountered. If suspected adverse reactions do occur, treatment should be discontinued.

Do not handle the product if you know you are sensitised or if you have been told not to work with such preparations. Wash hands after use and before meals. Keep out of the reach of children. For animal treatment only.

Legal category

POM-V

Package quantities

Available in polythene bags of 2kg, 3kg, 9kg, 12kg, 16kg, 20kg and 25kg and cartons containing 8 x 3kg, and 12 x 2kg polythene bags.

Marketing authorisation number

Vm 21766/4004

Marketing authorisation holder

Alpharma (Belgium) BVBA Garden Square Laarstraat 16 B-2610 Antwerp Belgium

Tel: Fax: Website:

+32 (0) 3 287 3880 +32 (0) 3 287 3881 www.alpharmaah.com

UK representative

Poultry Pigs

Tel: Tel:

AurofacÂŽ is a registered trademark of Alpharma Inc, Bridgewater, USA

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+44 (0) 7740 483818 +44 (0) 7717 345108

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Keep this Handbook up-to-date! When this Handbook was published, in February 2009, everything possible had been done by the publisher and product suppliers to ensure the information contained was accurate and up-to-date. Inevitably, some products will be subject to important changes between publication of this edition and the next. Whenever we are notified of changes to product information contained in this edition, these changes will be posted on our website at: www.simonmounsey.com/hbupdate.htm The updates will be in the form of replacement pages which can be printed out and used to replace pages in the original. As an additional service to users of this book, you may register to receive notification whenever an updated page is posted. Simply send an email to mail@simonmounsey.com with the subject line “Handbook Updates 2009� and your email address for notification.

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Aurofac速 250mg/g Granular Premix for Medicated Feeding Stuff

Presentation

A yellow to dark yellow, free-flowing granular premix for medicated feeding stuff containing 250g chlortetracycline hydrochloride per kg.

Uses

For treatment and control of respiratory and systemic infections associated with chlortetracycline-sensitive organisms.

Dosage/administration

Recommended doses of chlortetracycline hydrochloride are: Pigs: Layers: Broilers: Turkeys: Ducks:

10-20mg/kg bodyweight daily 20-25mg/kg bodyweight daily 20-30mg/kg bodyweight daily 10-30mg/kg bodyweight daily 10-30mg/kg bodyweight daily

These dose rates can usually be achieved by mixing 1.2kg of Aurofac速 250 mg/g Granular per tonne of complete feed to give a concentration of 300ppm chlortetracycline hydrochloride. However, the correct incorporation rate should always be calculated based on the feed consumption rates of the animals to be treated. To ensure thorough dispersion of the product, it should first be mixed with a suitable quantity of feed ingredients before incorporation into the final mix. Aurofac速 250 mg/g Granular can be incorporated in pelleted feed pre-conditioned at temperatures up to 70属C. The medicated feed should be supplied to the affected pen(s) or group(s) of pigs, chickens, turkeys or ducks. Treatment should be continued for a period of five to seven days for respiratory or systemic infections. During the treatment period, only feed medicated with the product should be supplied. Contra-indications, warnings, etc.

Do not use in ruminants. Withdrawal periods: Pigs (meat): Chickens (meat): Chickens (eggs): Turkeys (meat): Ducks (meat):

10 days 2 days 4 days 2 days 4 days

Not to be used in ducks producing eggs for human consumption.

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Pharmaceutical precautions

Store apart from animal feedstuffs. After first opening the bag of premix, any remaining contents should be stored in a dry place and the bag should be closed and secured with a suitable bag tie. Shelf-life of the veterinary medicinal product as packaged for sale: 2 years. Shelf-life after first opening the immediate packaging: 14 days. Shelf-life after incorporation into feed: as mash: 3 months; as pellets: 3 months. Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements.

General precautions

Chlortetracycline is of low toxicity and there is a wide safety margin at the recommended dosage. On rare occasions overdosage may cause diarrhoea and over growth of yeast and fungi. Under such conditions, withdraw medication and apply appropriate treatment.

Do not handle this product if you know you are sensitised or if you have been told not to work with such preparations. Handle this product with great care to avoid exposure taking all recommended precautions.

If you develop symptoms following exposure, such as skin rash, you should seek medical advice and show the doctor this warning. Swelling of the face or eyes or difficulty in breathing are more serious symptoms and require urgent medical attention. Wash hands after use and before meals.

Legal category

POM-V

Package quantities

Available in polyethylene bags containing 20kg.

Marketing authorisation number

Vm 21766/4005

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Marketing authorisation holder

Alpharma (Belgium) BVBA Garden Square Laarstraat 16 B-2610 Antwerp Belgium

Tel: Fax: Website:

+32 (0) 3 287 3880 +32 (0) 3 287 3881 www.alpharmaah.com

UK representative

Poultry Pigs

Tel: Tel:

Aurofac速 is a registered trademark of Alpharma Inc, Bridgewater, USA

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+44 (0) 7740 483818 +44 (0) 7717 345108

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Aurogran 500 Presentation

Premix for incorporation in animal feedingstuffs. Composition per kg: chlortetracycline hydrochloride 500g in a calcium carbonate carrier.

Uses

Pigs: As an aid in the control of diseases caused by chlortetracycline‑sensitive organisms. Chickens: Aurogran 500 is effective in the treatment and control of E. coli septicaemia secondary to Infectious Bursal Disease (Gumboro Disease), Chronic Respiratory Disease (CRD) caused by Mycoplasma gallisepticum and E. coli, and Salmonella enterica Enteritidis, Salmonella typhimurium, Riemerella anatipestifer and Pasteurella multocida infection. Turkeys: For the treatment and control of diseases responsive to chlortetracycline, including secondary E. coli infections involved in outbreaks of Turkey Rhinotracheitis (TRT).

Dosage/administration

To ensure thorough dispersion, Aurogran 500 should first be mixed with 25kg feed ingredients before incorporation in the final mix. For oral administration after incorporation in complete feed. Pigs: Aurogran 500 should be included in the feed to provide a dose of 20mg chlortetracycline/kg liveweight daily. Food intake varies with age, liveweight and physiological state and the concentration in feed should be varied according to daily feed intake. To achieve the target dosage in pigs of all classes, the following formula should be used: Inclusion rate of Aurogran 500 in feed (g/tonne) = 40 x bodyweight (kg) daily feed intake (kg) Chickens: Aurogran 500 should be included in the feed to achieve the recommended dose of 20-30mg chlortetracycline per kg bodyweight daily. The recommended level of chlortetracycline hydrochloride in feed is generally achieved at 300-400ppm, that is by mixing the product into the feed at a rate of 600-800g per tonne of complete feed.

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This is only a guide and the prescribing veterinarian is advised to check that the recommended inclusion levels do supply the required dose of chlortetracycline relative to the sensitivity of the causal organism, by using the following equation: Inclusion rate of Aurogran 500 in feed (kg/tonne) = dose rate (mg/kg bodyweight) x 2 daily feed intake (g/kg bodyweight per day) Treatment should be given for 5-7 days for pigs and chickens. Turkeys: Aurogran 500 should be included in the feed to achieve a dose rate of 20mg chlortetracycline hydrochloride per kg liveweight daily. This may be achieved by incorporation of 800g -1.2kg product per tonne of complete feed. Treat for ten consecutive days. Feed containing the product should constitute the entire feed provided for animals and birds during treatment. Treatment should be maintained until signs of disease are no longer apparent. The product can be added to feeds for pelleting. The product can be incorporated into pelleted feed at temperatures of up to 85°C. This premix may only be used at feed mills authorised to incorporate premixes into feedingstuffs at levels of less than 2kg per tonne. Contra‑indications, warnings, etc.

Animals and birds must not be slaughtered for human consumption during treatment.

Pigs may only be slaughtered for human consumption seven days after the last treatment. Chickens may only be slaughtered for human consumption three days after the last treatment. Turkeys may only be slaughtered for human consumption one day after the last treatment. Eggs from treated chickens must not be used for human consumption. Do not administer to ruminants. If administered to ruminating animals, toxicity is likely to be seen. Under practical conditions, the management of respiratory disease outbreaks recognises that ill animals are often inappetent and may require parenteral therapy.

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Allow animals and birds access to medicated feed only during treatment. Bacterial resistance may develop following long‑term use of chlortetracycline. This is particularly likely in enterobacteria and salmonella, many of which are already resistant. Salmonella shedding in treated animals will continue where the organisms are resistant. For animal treatment only. Operator warnings

Adequate measures must be taken not to create dust when incorporation of the product into feed is occurring. Persons handling the product should do so In a mechanically ventilated area. Wear either a disposable half-mask respirator conforming to European standard EN149 or a non-disposable respirator to European standard EN140 with a filter to EN143. Wear protective gloves and approved safety glasses. Wash exposed skin after use and before food. Do not smoke, eat or drink whilst using the product.

Pharmaceutical precautions

Do not store above 25°C. Store in a dry place. Protect from light. Keep out of the reach of children. Use only under veterinary direction. Aurogran 500 has a product shelf life of 12 months. In finished pig and poultry feeds, both mash and pellets, Aurogran 500 has a shelf life of three months.

Disposal advice

Any unused product or waste material should be disposed of in accordance with national requirements.

Legal category

POM-V

Package quantities

1kg, 2kg, 10kg and 25kg polyethylene-lined, laminated foil, heat-sealed bags.

Further information

Chlortetracycline is used as an antimicrobial in veterinary therapeutics. As with other tetracyclines, it is a broad spectrum antibiotic with a wide range of bacteriostatic activity against both gram-negative and gram-positive bacteria. Chlortetracycline appears to act by inhibiting the binding of aminoacyl-tRNA to the mRNA ribosome complex, thereby preventing the prokaryotic cell’s ability to synthesise proteins.

Following oral administration of a single dose, chlortetracycline is absorbed from the stomach and the first part of the small intestine to give a peak plasma concentration in 2-4 hours. A gradual fall in level follows: at 24 hours, the substance is barely detectable. Some of the drug is concentrated by the liver, excreted in bile and resorbed from the intestine; a small amount persists in the blood as a result of enterohepatic resorption.

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Marketing authorisation number

Vm 12501/4153

Marketing authorisation holder

Novartis Animal Health UK Ltd

Marketed and distributed by

Novartis Animal Health UK Ltd Frimley Business Park Frimley Camberley Surrey GU16 7SR

Tel: 01276 694402

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Availa®-Zn 100 EU Presentation

A fine, free-flowing brown powder with a sweet organic odour containing 10% Zn as zinc chelate of amino acids hydrate. International Feed Number (I.F.N.) 6-32-054. Slightly hygroscopic.

Use

As a nutritional feed additive for livestock and poultry.

Dosage/administration

Pigs *:

Poultry:

400g per tonne of complete ration.

Laying hens: Broilers: Turkeys:

400g per tonne of complete ration. 400g per tonne of complete ration. 400g per tonne of complete ration.

Dairy cows:

3.6g per head per day.

Beef cattle:

3.6g per head per day.

Sheep *:

0.4g per head per day.

Horses:

3.6g per head per day.

* Double recommended levels during periods of reduced feed intake.

Precautions

When used correctly, there is no toxicity hazard in the use of Availa-Zn 100 EU.

Package sizes

Multi-wall paper bags: 25kg.

Further information

For animal feed use only.

Storage Store under dry and normal storage conditions.

Shelf life Three years from the date of manufacture.

GMO-free product (EC1829 + 1830/2003).

When used as a commercial feed ingredient, it must be declared as ‘zinc chelate of amino acids hydrate’.

Legal category

Registered for use under EU directive 91/155/EEC.

EU authorisation

E6: zinc chelate of amino acids hydrate.

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Supplier

AB Vista™ 3 Woodstock Court Blenheim Road Marlborough Business Park Marlborough Wiltshire SN8 4AN United Kingdom

Telephone: Fax: Email: Website:

Contact

Earl Williams Telephone: 01609 785581 or 07831 626391

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+44 (0)1672 517650 +44 (0)1672 517660 info@ab-vista.com www.ab-vista.com

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Avatec速 15% CC (Game Birds) Presentation

A light brown, granular premix for inclusion into animal feedingstuffs. Avatec 15% CC (Game Birds) contains 15% w/w lasalocid sodium (150g lasalocid sodium per kg of premix) on a corn cob carrier.

Uses

As an aid in the prevention of coccidiosis caused by Eimeria duodenalis, E. colchici and E. phasiani in pheasants. As an aid in the prevention of coccidiosis caused by Eimeria legionensis and other Eimeria species in partridges.

Dosage/administration

Pheasants and partridges: Avatec 15% CC (Game Birds) should be thoroughly mixed into feed at inclusion rates within the range 600 to 800g per tonne of complete feedingstuffs in order to provide 90 to 120mg/kg lasalocid sodium in the finished feed. To be fed continuously from day-old to a maximum age of 12 weeks.

Contra-indications, warnings, etc.

For animal treatment only. For use in feeds for pheasants and partridges. Do not feed to other classes of birds or to other species of livestock. Not to be administered to laying birds. To ensure thorough dispersion of the product it should be first mixed with a suitable quantity of feed ingredients before incorporation in the final mix. Once incorporated into feed it has a maximum shelf life of three months Do not mix or use simultaneously with any other coccidiostat. Animals must not be slaughtered for human consumption during treatment. Pheasants and partridges may be slaughtered for human consumption only after seven days from the last treatment. When mixing or handling Avatec 15% CC (Game Birds), the usual precautions for the handling of powders should be observed: operators should wear protective clothing including a dust mask. Thoroughly wash after work and before meals. Keep out of reach of children.

Pharmaceutical precautions

Store in a cool, dry place.

Legal category

POM-V

Package quantities

20kg in polythene-lined multi-wall bags.

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Further information

When used as recommended this product should only be incorporated by Category A manufacturers.

Marketing authorisation number

Vm 21766/4002

Marketing authorisation holder

Alpharma (Belgium) BVBA Garden Square Laarstraat 16 B-2610 Antwerp Belgium

Tel: Fax: Website:

+32 (0) 3 287 3880 +32 (0) 3 287 3881 www.alpharmaah.com

UK representative

Tel:

+44 (0) 7740 483818

Avatec速 is a registered trade mark of Alpharma Inc, Bridgewater, USA

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Avatec速 150 G Premix Presentation

A reddish, dust-free, granular premix for inclusion into animal feedingstuffs. Avatec 150 G Premix contains 15% w/w lasalocid sodium (150g lasalocid sodium per kg of premix) on a mineral carrier.

Uses

As an aid in the prevention of coccidiosis caused by Eimeria necatrix, E. tenella, E. acervulina, E. brunetti, E. maxima and E. mivati in chickens for fattening and layer replacement chickens. As an aid in the prevention of coccidiosis caused by Eimeria meleagrimitis, E. gallopavonis, E. adenoides and E. dispersa in turkeys.

Dosage/administration

Chickens for fattening: Avatec 150 G Premix should be thoroughly mixed into feed at inclusion rates within the range 500 to 830g per tonne of complete feedingstuffs in order to provide 75 to 125g lasalocid sodium in the finished feed. The normal usage is 600g per tonne to give a concentration in the feed of 90mg/kg lasalocid sodium. To be fed continuously from day-old to no later than five days before slaughter. Layer replacement chickens: Avatec 150 G Premix should be thoroughly mixed into feed at inclusion rates within the range 500 to 830g per tonne of complete feedingstuffs in order to provide 75 to 125mg/kg lasalocid sodium in the finished feed. Feed containing Avatec 150 G Premix should be fed continuously from day-old to a maximum age of 16 weeks. Turkeys: Avatec 150 G Premix should be thoroughly mixed into feed at inclusion rates within the range 600 to 830g per tonne of complete feedingstuffs in order to provide 90 to 125mg/kg lasalocid sodium in the finished feed to be fed continuously from day-old to a maximum age of 12 weeks.

Contra-indications, warnings, etc.

For animal treatment only. For use in feeds for broiler chickens, other table chickens, layer replacement chickens, turkeys. Do not feed to other classes of birds or to other species of livestock. To ensure thorough dispersion of the product it should be first mixed with a suitable quantity of feed ingredients before incorporation in the final mix. Once incorporated into feed it has a maximum shelf life of three months Do not mix or use simultaneously with any other coccidiostat. Animals must not be slaughtered for human consumption during treatment. Chickens and turkeys may be slaughtered for human consumption only after five days from the last treatment.

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When mixing or handling Avatec 150 G Premix, the usual precautions for the handling of powders should be observed: operators should wear protective clothing including a dust mask. Thoroughly wash after work and before meals. Keep out of reach of children. Pharmaceutical precautions

Store in a cool, dry place.

Legal category

Specified feed additive (coccidiostat). (E763)

Package quantities

20kg in polythene-lined multi-wall bags.

Further information

When used as recommended this product should only be incorporated by Category A manufacturers.

Supplier

Alpharma (Belgium) BVBA Garden Square Laarstraat 16 B-2610 Antwerp Belgium

Tel: Fax: Website:

+32 (0) 3 287 3880 +32 (0) 3 287 3881 www.alpharmaah.com

UK representative

Tel:

+44 (0) 7740 483818

Avatec速 is a registered trade mark of Alpharma Inc, Bridgewater, USA

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Handbook of Feed Additives 2009 Handbook of Feed Additives 2009 is one of several directories, periodicals and reports published by Simon Mounsey Ltd. Amongst our other titles for feed producers and their suppliers are: • Feed Statistics 2009 • Feed Businesses 2009 • Feed Industry Review Details about these and other publications and services can be found on our website at: www.simonmounsey.com

Updates to this Handbook can also be found on the same website. You can go directly to the updates site at the following address: www.simonmounsey.com/hbupdate.htm

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Avizyme® 1200 Presentation

Avizyme 1200 is supplied as a light brown, fine granular product. Bulk weight: 650kg/m3 Moisture content: Maximum 12%

Use

Avizyme 1200 is a feed-enzyme system specifically developed to improve the nutritional value of wheat/barley-based broiler diets.

Dosage/administration

Broilers: Use at a rate of 0.25-1kg/tonne of complete feed as defined by the Avicheck™ dose optimisation service.

Use and Dosage/administration is subject to individual registration. For specific details contact supplier.

Package sizes

25kg multi-wall paper bags and 1000kg bulk (tote) bags.

Further information

Guaranteed minimum activity: 100 units beta-glucanase/g (IUB No. EC 3.2.1.6), 2500 units xylanase/g (IUB No. EC 3.2.1.8) and 800 units protease/g (IUB No. EC 3.4.21.62). Analysis methods are available upon request. Stability and storage: For optimum bioefficacy, do not exceed conditioning and pelleting temperatures of 85°C. Avizyme 1200 is stable for 12 months when stored in original packaging at ≤ 22°C and for 3 months when included in a vitamin/mineral premix. Store in dry conditions. Safety and purity: Available on request. There are no producing micro-organisms in the final product. None of the ingredients is of animal origin. Handling: Provide for good ventilation and avoid dust formation. It is recommended to use protective glasses, respiratory mask and gloves during handling. In case of accidental contact with skin or eyes, the only action needed is copious flushing with water. See the Material Safety Data Sheet for further information.

Legal category

Enzyme

Supplier

Danisco Animal Nutrition PO Box 777 Marlborough Wiltshire SN8 1XN Tel: Fax: E-mail: Web:

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01672 517777 01672 517778 info.animalnutrition@danisco.com www.danisco.com/animalnutrition

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Avizyme® 1210 Presentation

Avizyme 1210 is supplied as yellow to brown liquid. Specific gravity: Viscosity: Freezing point: pH:

1.14g/ml 5.5 cPs at 24°C -11°C 4.5-5.0

Uses

Avizyme 1210 is a liquid enzyme system specifically developed for improving the nutritional value of wheat/barley-based broiler and turkey diets.

Dosage/administration

Broilers: Use at a rate of 0.25-0.5kg/tonne of complete feed as defined by Danisco Animal Nutrition’s Avicheck™ dose optimisation service. Must apply post-pelleting.

Turkeys: Use at a rate of 0.25-0.5kg/tonne of complete feed as defined by Danisco Animal Nutrition’s Avicheck™ dose optimisation service. Must apply post-pelleting. Use and Dosage/administration is subject to individual registration. For specific details contact supplier.

Package sizes

Containers of 25kg, 200kg and 1000kg.

Further information

Guaranteed minimum activity: 50 units beta-glucanase/g (IUB No. EC 3.2.1.6) and 5000 units xylanase/g (IUB No. EC 3.2.1.8). Analysis methods, detailing assay conditions, are available upon request. Stability and storage: For any processing conditions, particularly where conditioning and pelleting temperatures exceed 85°C. Avizyme 1210 is stable for 6 months when stored in original packaging at ≤ 22°C. Do not freeze. Safety and Purity: Available upon request. There are no producing micro-organisms in the final product. None of the ingredients is of animal origin. Handling: Provide for good ventilation and avoid aerosol formation. It is recommended to use protective glasses, respiratory mask and gloves during handling. In case of accidental contact with skin or eyes, the only action needed is copious flushing with water. See the Material Safety Data Sheet for further information.

Legal category

Enzyme

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Supplier

Danisco Animal Nutrition PO Box 777 Marlborough Wiltshire SN8 1XN Tel: Fax: E-mail: Web:

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Avizyme® 1300 Presentation

Avizyme 1300 is supplied as a light brown, fine granular product. Bulk weight: 650kg/m3. Moisture content: Maximum 12%

◊ Use

Avizyme 1300 is a feed enzyme system specifically developed to improve the nutritional value of wheat-based broiler and duck diets.

◊ Dosage/administration

Broilers: Use at a rate of 0.2-1kg/tonne of complete feed as defined by Danisco Animal Nutrition’s Avicheck™ dose optimisation service. Ducks: Use at a rate of 1kg/tonne of complete feed. Use and Dosage/administration is subject to individual registration. For specific details contact supplier.

Package sizes

25kg multi-wall paper bags and 1000kg bulk (tote) bags.

Further information

Guaranteed minimum activity: 2500 units xylanase/g (IUB No. EC 3.2.1.8) and 800 units protease/g (IUB No. EC 3.4.21.62). Analysis methods detailing assay conditions are available upon request. Stability and storage: For optimum bioefficacy, do not exceed conditioning and pelleting temperatures of 85°C. Avizyme 1300 is stable for 12 months when stored in original packaging at ≤ 22°C and for 3 months when included in a vitamin/mineral premix. Store in dry conditions. Safety and purity: Available on request. There are no producing micro-organisms in the final product. None of the ingredients is of animal origin. Handling: Provide for good ventilation and avoid dust formation. It is recommended to use protective glasses, respiratory mask and gloves during handling. In case of accidental contact with skin or eyes, the only action needed is copious flushing with water. See the Material Safety Data Sheet for further information.

Legal category

Enzyme

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Supplier

Danisco Animal Nutrition PO Box 777 Marlborough Wiltshire SN8 1XN Tel: Fax: E-mail: Web:

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01672 517777 01672 517778 info.animalnutrition@danisco.com www.danisco.com/animalnutrition

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Keep this Handbook up-to-date! When this Handbook was published, in February 2009, everything possible had been done by the publisher and product suppliers to ensure the information contained was accurate and up-to-date. Inevitably, some products will be subject to important changes between publication of this edition and the next. Whenever we are notified of changes to product information contained in this edition, these changes will be posted on our website at: www.simonmounsey.com/hbupdate.htm The updates will be in the form of replacement pages which can be printed out and used to replace pages in the original. As an additional service to users of this book, you may register to receive notification whenever an updated page is posted. Simply send an email to mail@simonmounsey.com with the subject line “Handbook Updates 2009� and your email address for notification.

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Avizyme® 1310 Presentation

Avizyme 1310 is supplied as yellow to brown liquid. Specific gravity: 1.13g/ml Viscosity: 2.3 cPs at 24°C Freezing point: -10°C pH: 4.5-5.0

Uses

Avizyme 1310 is a liquid enzyme system specifically developed for improving the nutritional value of wheat-based broiler diets.

Dosage/administration

Broilers: Use at a rate of 0.1-0.5kg/tonne of complete feed as defined by Danisco Animal Nutrition’s Avicheck™ dose optimisation service. Must apply post-pelleting. Use and Dosage/administration is subject to individual registration. For specific details contact supplier.

Package sizes

Containers of 25kg, 200kg and 1000kg.

Further information

Guaranteed minimum activity: 5000 units xylanase/g (IUB No. EC 3.2.1.8). An analysis method, detailing assay conditions, is available upon request. Stability and storage: For any processing conditions, particularly where conditioning and pelleting temperatures exceed 85°C. Avizyme 1310 is stable for 6 months when stored in original packaging at ≤ 22°C. Do not freeze. Safety and Purity: Available on request. There are no producing micro-organisms in the final product. None of the ingredients is of animal origin. Handling: Provide for good ventilation and avoid aerosol formation. It is recommended to use protective glasses, respiratory mask and gloves during handling. In case of accidental contact with skin or eyes, the only action needed is copious flushing with water. See the Material Safety Data Sheet for further information.

Legal category

Enzyme

Supplier

Danisco Animal Nutrition PO Box 777 Marlborough Wiltshire SN8 1XN Tel: Fax: E-mail: Web:

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01672 517777 01672 517778 info.animalnutrition@danisco.com www.danisco.com/animalnutrition

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Belfeed B 1100 MP/ML Presentation

Belfeed B 1100 is supplied as an off-white granular product (MP) or as a liquid preparation (ML).

Use

Belfeed B 1100 is an endo-beta-xylanase produced by Bacillus subtilis specially developed to improve the nutritional value of arabinoxylan rich diets for pigs, piglets, broilers, layers, turkeys and ducks.

Dosage/administration

Use at a rate of 100g/tonne of complete feed.

Package sizes

25kg PE-lined multilayer paper sacks for Belfeed B1100MP (granular product) or 200kg / 1000kg container for Belfeed B1100ML (liquid product).

Further information

Guaranteed minimum activity 100 Xylanase IU/g (IUB No. EC 3.2.1.8). Analysis methods detailing assay conditions are available upon request.

Stability and storage For optimum bioefficacy, do not exceed conditioning and pelleting temperatures of 85째C. Belfeed B1100MP is stable for 12 months when stored dry in closed original packaging at room temperature; Belfeed B1100ML is stable for six months when stored in closed original container at <25째C.

Safety and purity Available on request.

There are no viable producing micro-organisms in the final product. None of the ingredients is of animal origin. Handling Provide for good ventilation and avoid dust formation. It is recommended to use protective glasses, respiratory mask and gloves during handling. In case of accidental contact with skin or eyes, the only action needed is copious flushing with water. See the Material Safety Data Sheet for further information.

Legal category

Enzyme E1606 EC Number 51

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Producer

Beldem SA rue Bourrie 12 B-5300 Andenne Belgium

Supplier

Wyreside Products Limited Lune Bank School Lane Pilling Preston PR3 6AA

Tel: 01253 790462 Fax: 01253 790778 Email: info@wyreside.com

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BetafinÂŽ LQD Presentation

Betafin LQD is supplied as a brown liquid.

Use

Liquid betaine for all poultry and pig diets.

Dosage/administration

Use at a rate of up to 4kg/tonne of complete feed.

Use and Dosage/Administration is subject to individual registration. For specific details contact supplier.

Package sizes

Available in bulk

Further information

Guaranteed minimum activity Contains 47% betaine. Stability and storage 24 months when stored in unopened container. Heat stable up to 200°C. Safety and purity Available on request. Handling Provide for good ventilation and avoid aerosol formation. It is recommended to use protective glasses, respiratory mask and gloves during handling. In case of accidental contact with skin or eyes, the only action needed is copious flushing with water. See the Material Safety Data Sheet for further information.

Legal category

Betaine feed grade.

Supplier

Danisco Animal Nutrition PO Box 777 Marlborough Wiltshire SN8 1XN Tel: Fax: E-mail: Web:

01672 517777 01672 517778 info.animalnutrition@danisco.com www.danisco.com/animalnutrition

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BetafinÂŽ S1 Presentation

Betafin S1 is supplied as free-flowing, light brown crystals.

Use

Dry betaine for all poultry, pig and fish diets.

Dosage/administration

Pigs and Poultry Use at a rate of up to 2kg/tonne of complete feed.

Fish and Shrimp Use at a rate of up to 15kg/tonne of complete feed.

Use and Dosage/Administration is subject to individual registration. For specific details contact supplier.

Package sizes

25kg multi-walled, polyethylene lined paper bags.

Further information

Guaranteed minimum activity Contains 96% betaine and 1.5% (max) calcium stearate for product flowability. Stability and storage 24 months when stored in original unopened packaging and protected from humidity. Heat stable up to 200°C. Safety and purity Available on request. Handling Provide for good ventilation and avoid formation of dust during handling. Due to the hygroscopic nature of the product, avoid prolonged contact with skin, eyes and mucous membranes. In case of accidental contact with skin or eyes, rinse with water. See the Material Safety Data Sheet for further information.

Legal category

Betaine anhydrous feed grade.

Supplier

Danisco Animal Nutrition PO Box 777 Marlborough Wiltshire SN8 1XN Tel: Fax: E-mail: Web:

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01672 517777 01672 517778 info.animalnutrition@danisco.com www.danisco.com/animalnutrition

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Beta-Key

new

Presentation

Beta-Key is a white crystalline powder with excellent free-flowing characteristics and vitamin-like biological effects.

Product information

Specification Betaine hydrochloride: C5H11NO2.HCl

Product composition Betaine hydrochloride: 93% (guaranteed minimum) Pure Betaine: 70.7% (guaranteed minimum)

Uses

Betaine is used as a methyl donor in diets for all poultry, pigs and fish.

Dosage/administration

Depends on animal species and dietary basal levels of choline and betaine. Betaine may replace all added choline (200-800ppm). For specific applications, advised dosages may go up as far as 2000ppm.

Legal category

Category 3a (Annex I Reg 1831/2003).

Chemically well-defined substance having a similar biological effect to vitamins.

Storage

Shelf life: 3 years from production date.

Package quantities

25kg bags.

Supplier

Orffa Additives BV Vierlinghstraat 51 4251 LC Werkendam The Netherlands

Orffa UK Office PO Box 113 Northallerton North Yorkshire DL6 1YH

Tel: +31 (0) 183 44 77 44 Fax: +31 (0) 183 44 30 60 E-mail: info@orffa.com Website: www.orffa.com

Tel: +44 (0) 1609 772881 Fax: +44 (0) 1609 780941

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Biogrow Presentation

Biogrow is a powder in which the active ingredients are equal amounts of the spray dried spore‑forming bacteria Bacillus licheniformis and Bacillus subtilis at a minimum concentration of 3.2 x 109 viable spores/g. Bacillus licheniformis and Bacillus subtilis are bacteria which after intake are distributed in the gastrointestinal tract where they produce starch‑degrading enzymes (amylases), protein‑degrading enzymes (proteases) and fat‑degrading enzymes (lipases). These enzymes all contribute to the digestion of feed components into substances which are easily utilised by the animal.

Application areas

Feed additive for pigs (piglets, sows and slaughter pigs), calves and poultry (broilers, turkeys). Can be blended into ready‑to‑use rations. In feed pelletised at 75°C-95°C approximately 85 per cent of spores will be recovered. May be used in compound feeds containing the following coccidiostats or medical substances: salinomycin sodium, monensin sodium, meticlorpindol, methylbenzoquate, robenidine, nicarbazin, amprolium ethopabate, diclazuril, nifursol, halofuginone.

Dosage/administration

Piglets up to 2 months: 0.4-1.0kg per tonne feed, equivalent to a concentration of 1.28-3.2 million spores per gram of feed. Sows (15 days pre partum and during lactation period): 0.3-0.6kg per tonne feed, equivalent to a concentration of 0.96-1.92 million spores per gram of feed. Pigs for fattening: 0.15-0.4kg per tonne feed, equivalent to a concentration of 0.48-1.28 million spores per gram of feed. Chickens for fattening: 1.0kg per tonne feed, equivalent to a concentration of 3.2 million spores per gram of feed. Turkeys for fattening: 0.4-1.0kg per tonne feed, equivalent to a concentration of 1.28-3.2 million spores per gram of feed. Calves up to 6 months: 0.4-0.5kg per tonne feed, equivalent to a concentration of 1.28-1.6 million spores per gram of feed.

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Product information

Microbiological specifications Spores of Bacillus licheniformis CH200 >1.6 x 109/gram (Typically not more than 3 x 109 spores/g)

Spores of Bacillus subtilis >1.6 x 109/gram (Typically not more than 3 x 109 spores/g) Salmonella spp. <1 in 25g Coliforms < 103/g Bacillus cereus < 102/g Yeast and Moulds < 103/g Chemical Specifications

Freeze‑dried Bacillus spore concentrate

1%

(equal amounts of Bacillus licheniformis and Bacillus subtilis) Synthetic (sodium) aluminium silicate (E554)

Spray‑dried whey permeate powder Heavy metals

1% 98% <0.5mg/kg

Antibiotic residues

not detectable

Dioxin

not detectable

Physical Specifications Solubility at 25°C: carrier partially soluble, spores suspendible. Powder: non‑electrostatic, slightly hygroscopic and free‑flowing. Colour: yellowish. Density: Typically 0.80‑0.90 grams/cm³. Particle size: Typically 1.3% <10 micron, 13.9% <50 micron, 51.9%<100 micron and 91.3% <200 micron. Loss on drying: 1.5 – 5.0% (Typically not more than 2‑3%). Further information

Storage and Handling Must be kept in a dry room at temperatures not exceeding 37°C to maintain optimal activity.

Stability

Minimum 18 months from the production date when stored as specified above. Biogrow mixed with feedingstuff for piglets, slaughter pigs, sows, calves and poultry maintains the original specifications after storage at 25°C for a minimum of 24 months.

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Packaging

20kg foil bags and 1kg tubs.

Premix available on request.

Safety

Avoid inhalation of dust. In case of inhalation, skin contact or eye contact, rinse with water. In case of oral intake dilute with water. Face mask should be worn if dust formation occurs. Non flammable. Not classified as chemical waste.

Withdrawal period

Nil.

Legal category

Enzyme/micro-organism product.

Registration Numbers: E1700 (piglets), E20 (others).

Supplier

Provita Eurotech Ltd 21 Bankmore Road Omagh County Tyrone Northern Ireland BT79 0EU Tel: Fax:

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028 82 252352 028 82 241734

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BioPlus® 2B Presentation

BioPlus® 2B is a powder, containing spores of Bacillus licheniformis (DSM 5749) at a minimum of 1.6x109 colony forming units (CFU)/g and Bacillus subtilis (DSM 5750) at a minimum of 1.6x109 CFU/g. The active ingredients will retain their activity after pelleting at 75-95°C. The Bacillus strains survive passage through the stomach and produce protease, amylase and lipase enzymes in the gastrointestinal tract, which increase the digestion of protein, starch and fat respectively. This leads to increased liveweight gains and improved feed conversion ratios.

Uses

Microbial feed additive for piglets, grower and finisher pigs, sows (two weeks before farrowing and during lactation), turkeys and calves (up to three months of age). BioPlus® 2B is EU approved as compatible with the following coccidiostats: diclazuril, halofuginone, maduramicin ammonium, monensin sodium and robenidine. It is also tested to be compatible with other coccidiostats: amprolium/ethopabate, lasalocid sodium, methylbenzoate/meticlorpindol, nicarbacin, nifursol and salinomycin sodium.

Dosage

Animal Group

Dosage

CFU/g

Piglets

400-1000g/tonne

(1.3-3.2) x106

Growers/finishers

400g/tonne

(1.3) x106

Sows

400g/tonne

(1.3) x106

Turkeys

400g/tonne

(1.3) x106

Calves

400g/tonne

(1.3) x106

Safety

As with all powders avoid inhalation of dust. A facemask, gloves and goggles should be worn when handling larger amounts of the product. In case of inhalation seek fresh air and avoid further contact. In case of skin or eye contact rinse with water. In case of oral intake, drink plenty of water to dilute. The product is of no hazard according to the legislation on chemicals and hazardous substances.

Legal category

BioPlus® 2B is approved under EU Registration number E1700 for piglets, grower/finisher pigs, sows, turkeys and calves.

Storage

Store in a cool, dry place at temperatures not exceeding 25°C. The bag must be closed again after use.

Shelf life

Minimum 24 months when stored as specified above.

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Packaging

In 20kg net weight quantities in bags.

Supplier

Chr. Hansen (UK) Ltd. 2 Tealgate Charnham Park Hungerford Berkshire RG17 0YT

Tel: Fax: Contact:

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01488 689800 01488 685436 Dr David Seale

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Biosprint Presentation

Viable cells of a specific strain of Saccharomyces cerevisiae BCCMâ&#x201E;˘/MUCL*-39885 with a minimum concentration of 15 x 109 colony forming units per gram (CFU/g). Presented as fine brown micro-granules.

Uses

Ruminants For incorporation into the diets of cattle to stimulate beneficial rumen microbial activity. Modulates and synchronises proteolytic and cellulolytic rumen action, improving energy and protein efficiency in the diet. Increased feed intake, improved fatty acid supply and improved pH stability have been documented.

Monogastrics To maintain and enhance beneficial gut micro flora in piglets. Improved feed conversion efficiency and weight gain have been documented.

Dosage/administration

Dairy Cattle 2.0-3.2g per head per day.

Beef Cattle 1.0-1.6g per head per day.

The quantity of Biosprint in the daily ration must not exceed: 1.6x1010 CFU per 100kg body weight, add 3.2 x 109 for each additional 100kg body weight.

Piglets 300g per tonne of feed.

Do not exceed 2kg per tonne of feed.

Further information

Dairy Cattle Data submitted to the EC Standing Committee on the Food Chain and Animal Health, Animal Nutrition Section, for inclusion in the Community Register of Feed Additives has demonstrated increased milk yield of up to 2.68 litres/head/day and improved protein yield.

Beef Cattle Data submitted to the EC Standing Committee on the Food Chain and Animal Health, Animal Nutrition Section, for inclusion in the Community Register of Feed Additives has demonstrated an increase in average daily live weight gain in the range 7.310.6%.

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Piglets Data submitted to the EC Standing Committee on the Food Chain and Animal Health, Animal Nutrition Section, for inclusion in the Community Register of Feed Additives has demonstrated a significant increase in average daily live weight gain in the range 4.0-8.2%.

Precautions

Store in a cool, dry place away from animals and children. No hazards have been identified with Biosprint.

Packaging quantities

Biosprint is available in 15kg boxes.

Shelf life

12 months from date of manufacture.

Legal category

Micro-organism product (Regulation (EC) No 1831/2003).

EU registration

Biosprint is registered as E1710 for use in dairy cattle, beef cattle and piglets.

Supplier

Scotmin Nutrition Limited 13 Whitfield Drive Heathfield Industrial Estate Ayr KA8 9RX Tel: 01292 280909 Fax: 01292 280919 E-mail: admin@scotmin.com Website: www.scotmin.com Belgian Co-ordinated Collections of Micro-organisms / Mycotheque de lâ&#x20AC;&#x2122;Universite Catholique de Louvain.

*

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Bloat Guard Premix Presentation

A powder premix containing 53% w/w poloxalene.

Uses

For the prevention of frothy bloat in cattle.

Dosage/administration

For oral use only: The normal dosage rate is 1g product per 24kg bodyweight (22mg poloxalene/kg bodyweight) per day. This may be increased to 2g product per 24kg bodyweight (44mg poloxalene/kg bodyweight) per day if the risk of bloat is high. The required amount of Bloat Guard Premix must be incorporated in the feedingstuff either in the final stages of mixing or in a feed supplement or concentrate. Inclusion levels vary depending on the animal’s bodyweight and daily feed intake. The product should be administered 2-3 days before the anticipated period of risk and throughout the period of risk. If these measures do not appear effective, the possibility of an acidosis/digestive disturbance should be considered and veterinary advice sought.

Contra-indications, warnings, etc.

Animals must not be slaughtered for human consumption during treatment. Cattle may be slaughtered for human consumption only after three days from the last treatment. Withdrawal period for milk – zero hours. For animal treatment only. Keep out of the reach of children.

Pharmaceutical precautions

Do not store above 25°C. Store in a dry place.

The product will remain stable in finished feed for three months.

Legal category

POM-V.

Package quantities

10kg bag.

Further information

The product may only be supplied on veterinary prescription.

A manufacturer who is approved to incorporate directly at any concentration, veterinary medicinal products or premixtures containing such products, must be responsible for mixing when incorporation is less than 2kg per tonne of final feed.

When incorporating into feed, to ensure thorough dispersion of the product, it should first be mixed with a suitable quantity of feed ingredients before incorporating in the final mix.

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Marketing authorisation number

04261/4001.

Marketing authorisation holder

Agrimin Ltd The Flarepath Elsham Wold Industrial Estate Brigg Lincolnshire DN20 OSP

Tel: Fax: Email:

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(01652) 688046 (01652) 688049 info@agrimin.co.uk

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BMP™ – Cobalt 5% Presentation

A uniform violet BMP™ granule containing basic cobaltous carbonate monohydrate to give a cobalt content of 5% w/w. Cobalt Content 5% ± 10% (4.5%-5.5%) by AA. Dust Emissions Total Dust emissions < 2.0mg at the filter by Heubach Type II (Stauber-Heubach) method. Cobalt Dust Emissions < 0.1mg at the filter by Heubach Type II (Stauber-Heubach) method.

Uses

For use in animal nutrition as a source of supplementary cobalt in all species and classes of livestock.

Active ingredient

Basic cobaltous carbonate monohydrate – 2CoCO3.3Co(OH)2. H2O

EU number

E3

Rates of use

Species & class of livestock

Maximum Content of Cobalt in mg/kg in Complete Feeding Stuffs

All animals

2 (total)

Warnings

For further processing only. Do not feed direct.

Handling

BMP – Cobalt 5% is safe to handle providing that good manufacturing practices and hygiene procedures are observed. For complete occupational safety information refer to Product Safety Data Sheet.

Storage

Store in a cool dry place away from animals and children.

Transport

BMP – Cobalt 5% is not classified as hazardous for conveyance.

Packaging

25kg in multi-ply paper sacks with integral moisture barrier.

Manufacturer

Doxal Italia SpA

Supplier

Norfeed UK Ltd Station Terrace Langthorpe Boroughbridge North Yorkshire YO51 9BU Tel: Fax: Email:

01423 324714 01423 326347 admin@norfeed.co.uk

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BMP™ – Selenium 1% Presentation

A uniform light tan BMP™ granule containing sodium selenite (2.2% w/w) to give a selenium content of 1% w/w. Selenium Content 1% ± 10% (0.90%-1.10%) by iodometric titration. Dust Emissions Dust emissions < 0.1mg at the filter by Heubach Type II (StauberHeubach) method

Uses

For use in animal nutrition as a source of supplementary selenium in the species and classes listed below.

Active ingredient

Sodium selenite (99.8% min.); Na2SeO3

EU number

E8

Rates of use

Species & class of livestock

Maximum Content of Selenium in mg/kg in Complete Feedingstuffs

All Species

0.5 (total)

Warnings

For further processing only. Do not feed direct. Do not exceed the maximum permitted rates of use.

Handling

BMP – Selenium 1% is safe to handle providing that good manufacturing practices and hygiene procedures are observed. For complete occupational safety information refer to Product Safety Data Sheet.

Storage

Store in a cool dry place away from animals and children. Store away from oxidising agents.

Transport

BMP – Selenium 1% is not classified as hazardous for conveyance.

Packaging

25kg in multi-ply paper sacks with integral moisture barrier.

Manufacturer/Supplier

Norfeed UK Ltd Station Terrace Langthorpe Boroughbridge North Yorkshire YO51 9BU Tel: Fax: Email:

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01423 324714 01423 326347 admin@norfeed.co.uk

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Cabanin® CS Powder

Presentation

Cabanin® CS Powder is a natural feed premix (mixture of flavouring compounds). The product combines the effects obtainable from concentrated citrus elements with those of sweet chestnut Castanea sativa Mill and grape Vitis vinifera. Cabanin® CS Powder contains Sepiolite (E562) as a carrier and propyleneglycol (E490) as a dust-reducer. The product is formulated as a free-flowing powder suitable for use by premixers, feed manufacturers and farmers.

◊ Uses

Cabanin® CS Powder is specifically developed for pigs of all ages. In addition, Cabanin® CS Powder can act as a partial substitute for vitamin E.

◊ Dosage/administration

The following inclusion rates are recommended: Piglets up to 25kg:

1.5-2.0kg per tonne of feed

Growers and finishers:

1.0-1.5kg per tonne of feed

1kg pure vitamin E 100% oil can be substituted by 3-3.75kg Cabanin® CS Powder 1kg vitamin E50% adsorbate can be substituted by 1.5-1.9kg Cabanin® CS Powder 1kg natural alpha-tocopherol can be substituted by 3.75-4.5kg Cabanin® CS Powder Precautions

Cabanin® CS Powder should be stored in a cool, dry place. It has a shelf life of at least 12 months when kept in unopened, or tightly reclosed, packaging.

Legislation

The raw materials in Cabanin® CS Powder are notified as sensory additives in EU Regulation (EC) No 1831/2003 concerning feed additives. Cabanin® CS Powder is encompassed by a European Patent – no. 1323354.

Package quantities

Cabanin® CS Powder is available in 25kg paper bags.

Supplier

Nor-Feed A/S Kanalholmen 2 2650 Hvidovre Denmark Tel: Fax: Email: Web:

0045 3649 8267 0045 3677 0266 office@norfeed.net www.norfeed.net

® Cabanin is a registered trademark of Nor-Feed A/S

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Calsporin®

new

Presentation

Calsporin® is a light tan powder containing viable spores of Bacillus subtilis on a calcium carbonate carrier.

Product information

Specification Bacillus subtilis: C-3102

Uses

Activity 1.0 x 1010 CFU/g (guaranteed minimum) Calsporin® is a spore-forming probiotic used in broiler chicken diets to balance gut flora, improve growth and feed conversion ratio.

Dosage/administration

50-100ppm (50-100g/tonne of final feed) for chickens for fattening from day 0 to slaughter.

Legal category

Category 4b (Annex I Reg 1831/2003) – code 4b1820.

Gut flora stabilizer.

Registration for chickens for fattening from day 0 to slaughter.

Further information

Shelf life 3 years from production date.

Stability Calsporin® is heat-stable up to 90°C.

Compatibility Calsporin® is compatible with in-feed coccidiostats, organic acids and therapeutically used antimicrobials.

Package quantities

20kg cardboard boxes containing 2x10kg inner vinyl bags.

Supplier

Orffa Additives BV Vierlinghstraat 51 4251 LC Werkendam The Netherlands

Orffa UK Office PO Box 113 Northallerton North Yorkshire DL6 1YH

Tel: +31 (0) 183 44 77 44 Fax: +31 (0) 183 44 30 60 E-mail: info@orffa.com Website: www.orffa.com

Tel: +44 (0) 1609 772881 Fax: +44 (0) 1609 780941

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CAROPHYLL® Pink (10% CWS) Presentation

CAROPHYLL® Pink 10% CWS consists of violet-brown to brownviolet free-flowing particles (beadlets). They contain astaxanthin in a corn-starch coated matrix of lignosulphonate and corn oil. Ethoxyquin is added as an antioxidant. Bulk density is approximately 0.5-0.6kg/litre and the product contains approximately 100,000 particles per gram. CAROPHYLL® Pink 10% CWS is dispersible in cold water, yielding a red coloration. Preparation of Solutions: Slowly add the powder to 10-15 times its weight in cold or warm water under continuous stirring.

Uses

Astaxanthin is an approved feed colourant for use up to a maximum of 100ppm in complete feeds for salmon and trout and in feeds for ornamental fish (no limit stated) to improve the pigmentation of flesh and skin.

Dosage/administration

Dose rates are dependent upon target species and degree of pigmentation required – contact DSM for further details.

Contra-indications/ precautions

For animal use only. The product is safe for the intended use. Avoid ingestion, inhalation of dust or direct contact by applying suitable protective measures and personal hygiene. For full safety information and necessary precautions, please refer to the respective DSM Product Specification and Safety Data Sheets.

Additive functional group

Colourant.

Packaging quantities

20kg carton with aluminium in-liner

Further information

CAROPHYLL® Pink 10% CWS is sensitive to air, heat, light and humidity. The product may be stored for 36 months from the date of manufacture in the unopened original container and at a temperature below 15°C. The ‘best use before’ date is printed on the label. Keep the container tightly closed. Once opened, use contents quickly.

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Supplier

DSM Nutritional Products (UK) Ltd Heanor Gate Heanor Derbyshire DE75 7SG

Tel: Fax: Website:

01773 536500 01773 536600 www.dsmnutritionalproducts.com

CAROPHYLL速 is a registered trademark.

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CAROPHYLL® Red 10% Presentation

CAROPHYLL® Red 10% consists of violet-red to red-violet, freeflowing particles (beadlets). They contain canthaxanthin in a corn starch-coated matrix of lignosulphonate. Ethoxyquin is added as an antioxidant. Bulk density is approximately 0.68g/cm3 and the product is dispersible in water.

◊ Uses

For use in poultry, salmon and trout feeds with specific limitations; in cats and dogs, ornamental fish and in pet and ornamental bird feeds. In feed for crustaceans where permitted by local legislation only.

Dosage/administration

Dose rates are dependent upon target species and degree of pigmentation required – contact DSM for further details.

Contra-indications/ precautions

For animal use only. The product is safe for the intended use. Avoid ingestion, inhalation of dust or direct contact by applying suitable protective measures and personal hygiene. For full safety information and necessary precautions, please refer to the respective DSM Product Specification and Safety Data Sheets.

Additive functional group

Colourant.

Packaging quantities

20kg multi-walled paper sacks with aluminium in-liner.

Further information

CAROPHYLL® Red 10% is sensitive to air, heat, light and humidity. The product may be stored for 18 months from the date of manufacture in the unopened original container and at a temperature below 15°C. The ‘best used before’ date is printed on the label. Keep the container tightly closed. Once opened, use contents quickly.

Supplier

DSM Nutritional Products (UK) Ltd Heanor Gate Heanor Derbyshire DE75 7SG

Tel: Fax: Website:

01773 536500 01773 536600 www.dsmnutritionalproducts.com

CAROPHYLL® is a registered trademark.

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CAROPHYLL® Yellow 10% Presentation

CAROPHYLL® Yellow 10% consists of brown-red free-flowing particles (beadlets). They contain apocarotenoic ester in a cornstarch-coated matrix of lignosulphonate. Ethoxyquin is added as an antioxidant.

Bulk density is approximately 0.63g/cm3 and the product is dispersible in water at 20°C or above.

Uses

As a feed additive for the pigmentation of egg yolks and broiler skin.

Dosage/administration

Dose rates are dependent upon the degree of pigmentation required – contact DSM for further details.

Contra-indications/ precautions

For animal use only. The product is safe for the intended use. Avoid ingestion, inhalation of dust or direct contact by applying suitable protective measures and personal hygiene. For full safety information and necessary precautions, please refer to the respective DSM Product Specification and Safety Data Sheets.

Additive functional group

Colourant.

Packaging quantities

20kg multi-walled paper sacks with aluminium in-liner

Further information

CAROPHYLL® Yellow 10% is sensitive to air, heat, light and humidity. The product may be stored for 18 months from the date of manufacture in the unopened original container and at a temperature below 15°C. The ‘best used before’ date is printed on the label. Keep the container tightly closed. Once opened, use contents quickly.

Supplier

DSM Nutritional Products (UK) Ltd Heanor Gate Heanor Derbyshire DE75 7SG

Tel: Fax: Website:

01773 536500 01773 536600 www.dsmnutritionalproducts.com

CAROPHYLL® is a registered trademark.

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Clinacox®

Presentation

A cream to amber powder for inclusion in animal feedingstuffs. Each kg of premix contains 5g diclazuril (0.5% w/w).

◊ Uses

As an aid in the prevention of coccidiosis in broiler chickens and replacement pullets caused by Eimeria acervulina, E. brunetti, E. maxima, E. mitis, E. necatrix and E. tenella. As an aid in the prevention of coccidiosis in growing turkeys up to 12 weeks caused by Eimeria adenoides, E. gallopavonis, E. meleagrimitis and E. dispersa. As an aid in the prevention of coccidiosis in rabbits caused by Eimeria flavescens, E. intestinalis, E. irresidua, E. magna, E. perforans, E. piriformis and E. stiedae.

◊ Dosage/administration

200g of Clinacox should be mixed per tonne of complete feed. This results in a final concentration of 1g diclazuril per tonne of feed (1mg/kg). For chickens, feed containing Clinacox may be given in pelleted or meal form and can be fed continuously as the only ration from one day old. For turkeys, feed containing Clinacox may be given in pelleted or meal form and can be fed continuously from one day old up to a maximum age of 12 weeks. For rabbits, feed containing Clinacox may be given in pelleted or meal form and can be fed continuously as the only ration from day old. To ensure thorough dispersion of the product it should first be mixed with a suitable quantity (20-50kg) of feed ingredients before incorporation in the final mix.

◊ Contra-indications, warnings, etc.

Clinacox should not be mixed or used simultaneously with any other anticoccidial. Treated poultry – chickens for fattening and turkeys may be slaughtered for human consumption after treatment, a withdrawal period of zero days. Treated rabbits must not be slaughtered for human consumption. They may be slaughtered for human consumption only after one day from the last treatment.

For animal treatment only. Keep out of reach of children. As with all medicated feedstuffs operators are advised to use protective clothing, gloves, dust mask and goggles when mixing or handling Clinacox.

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Pharmaceutical precautions

Store in a dry place below 25°C. When preconditioned with steam for up to five minutes and at temperatures up to 70°C under normal conditions of commercial pelleting, Clinacox will remain stable for up to six months. Clinacox in unpelleted feed will remain stable for up to six months.

Legal category

Specified feed additive (coccidiostat).

Package quantities

20kg bags.

EU authorisation number

E 771

Further information

Only to be incorporated by a manufacturer who is approved to mix at a rate of below 2kg per tonne of final feed.

Manufacturer

Janssen Pharmaceutica NV

◊ Distributor

Huvepharma NV Uitbreidingstraat 80 2600 Antwerp Belgium Tel: Fax: Email: Web:

0032 3 288 1849 0032 3 289 7845 customerservice@huvepharma.com www.huvepharma.com

®Registered trade mark.

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Coxidin® 200 microGranulate ◊ Presentation

A brownish dust free granular premix containing monensinsodium equivalent to 200g/kg of premix. For incorporation into animal feedingstuffs.

Uses

For the prophylactic control of the coccidial species Eimeria acervulina, E. brunetti, E. maxima, E. mivati, E. necatrix and E. tenella affecting chickens for fattening and E. adenoides, E. meleagrimitis and E. gallopavonis affecting turkeys for fattening.

◊ Dosage/administration

For chickens for fattening, add 500-625g Coxidin® 200 microGranulate per tonne of finished feed to provide a concentration of 100-125mg/kg monensin sodium in the final feed. For turkeys for fattening, add 300-500g Coxidin® 200 microGranulate per tonne of finished feed to provide a concentration of 60-100mg/kg monensin sodium up to a maximum age of 16 weeks. The product should be mixed into a secondary premix prior to incorporation into finished feed.

◊ Contra-indications, warnings, etc.

For use in chickens for fattening and turkeys for fattening only.

Not to be mixed or used simultaneously in feeds containing any other medicinal product or substance having a similar effect.

Not to be used in breeding birds.

Equines should be kept away from feed containing monensin: feeding monensin to horses has proved fatal. Coxidin® 200 microGranulate contains an ionophore: simultaneous use with certain medicinal substances e.g. tiamulin, erythromycin, oleandomycin, sulphadimethoxine, sulphadimidine and sulphaquinoxaline can be contraindicated. Operators handling the product should wear a face mask, gloves and protective clothing and avoid inhalation of and contact with the product. If Coxidin® 200 microGranulate accidentally enters the operator’s eyes, rinse out with water immediately. Wash hands and exposed skin after handling the product.

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Withdrawal period Animals must not be slaughtered for human consumption during treatment. Broiler chickens and turkeys may be slaughtered for human consumption only after one day from the last treatment. Harmful to wildlife. Do not leave or dispose of Coxidin速 200 microGranulate where it may be accessible to animals not under treatment or to wildlife. For animal treatment only. Keep out of reach of children. Pharmaceutical precautions

Expiry date is two years from the date of production when Coxidin速 200 microGranulate is stored in the original packaging. To ensure thorough dispersion, the product should first be mixed with a suitable quantity of feed before incorporation in the final mix. The product will remain stable in finished feed for three months.

Legal category

Specified feed additive (coccidiostat).

Package quantities

25kg bags, 750kg bags.

Further information

When used as recommended this product should only be incorporated by Category A manufacturers.

Supplier

Huvepharma NV Uitbreidingstraat 80 2600 Antwerp Belgium Tel: Fax: Email: Web:

0032 3 288 1849 0032 3 289 7845 customerservice@huvepharma.com www.huvepharma.com

速Registered trade mark.

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CRINA® Finishing Pigs and Sows Presentation

CRINA® Finishing Pigs and Sows is a blend of flavouring compounds for animal nutrition. Appearance: Structure: Odour:

yellow to light brown free-flowing, non-dusty powder characteristic odour

CRINA® Finishing Pigs and Sows is a carefully balanced combination of essential oil compounds of high purity in their natural / nature-identical form on a carrier. Uses

CRINA® Finishing Pigs and Sows stimulates digestive functions and improves digestibility of nutrients. CRINA® Finishing Pigs and Sows helps to regulate gut microflora balance, thus maintaining healthy gut function and reduces intestinal disorders such as diarrhoea.

Recommended dosage

75-150mg/kg of feed for finishing pigs and for sows.

Stability

CRINA® Finishing Pigs and Sows is stable in premixes as well as in mash, pelleted or expanded feed. Stored in a dry place and at a temperature below 25°C in original unopened bags, CRINA® Finishing Pigs and Sows can be kept for up to one year after production. Prolonged storage at temperatures above 30°C should be avoided. The best used before date is printed on the label. Keep container tightly closed. Once opened, contents should be used quickly. Avoid storage of CRINA® Finishing Pigs and Sows in plastic or plexiglass containers.

Palatability

At the recommended dosage CRINA® Finishing Pigs and Sows is readily accepted. At three times the recommended level feed refusal might be observed.

Precautions

Avoid unnecessary contact with the product or inhalation of dust. It is recommended to wear protective glasses and gloves when handling the product. In case of accidental access to non-target animals, CRINA® Finishing Pigs and Sows is safe and presents no hazards.

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Compatibilty

CRINA® Finishing Pigs and Sows is compatible with other commonly used feed additives such as enzymes, acidifiers, etc.

Packaging

CRINA® Finishing Pigs and Sows is available in 25kg pinch bottom bags with two external paper layers and one layer of polyethylene / aluminium / polyethylene on the inside.

Legislation

All compounds used in the CRINA® products are approved for food and appear on the FEMA/GRAS listing.

For EU countries, CRINA® Finishing Pigs and Sows complies with the current feed additive legislation (EEC 1831/2003) and the legislation concerning the undesirable substances and products in animal nutrition (Directive 1999/29/EEC as amended). CRINA® Finishing Pigs and Sows is classified as a ‘Sensory Additive’.

Supplier

DSM Nutritional Products (UK) Ltd Heanor Gate Heanor Derbyshire DE75 7SG

Tel: Fax: Website:

01773 536500 01773 536600 www.dsmnutritionalproducts.com

CRINA® is a registered trademark.

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CRINA® Piglets Presentation

CRINA® Piglets is a blend of flavouring compounds for animal nutrition. Appearance: Structure: Odour:

yellow to light brown free-flowing, non-dusty powder characteristic odour

CRINA® Piglets is a carefully balanced combination of essential oil compounds of high purity in their natural / nature-identical form on a carrier. Flavoured versions available upon request. Flavours are used to mask odour of active ingredients and to regulate/improve feeding behaviour. Uses

CRINA® Piglets stimulates digestive functions and improves digestibility of nutrients. CRINA® Piglets helps to regulate gut microflora balance, thus maintaining healthy gut function and reduces intestinal disorders such as diarrhoea.

Recommended dosage

100-200mg/kg of feed for piglets.

Stability

CRINA® Piglets is stable in premixes as well as in mash, pelleted or expanded feed. Stored in a dry place and at a temperature below 25°C in original unopened bags, CRINA® Piglets can be kept for up to one year after production. Prolonged storage at temperatures above 30°C should be avoided. The best used before date is printed on the label. Keep container tightly closed. Once opened, contents should be used quickly. Avoid storage of CRINA® Piglets in plastic or plexiglass containers.

Palatability

At the recommended dosage CRINA® Piglets is readily accepted. At three times the recommended level feed refusal might be observed.

Precautions

Avoid unnecessary contact with the product or inhalation of dust. It is recommended to wear protective glasses and gloves when handling the product. In case of accidental access to non-target animals, CRINA® Piglets is safe and presents no hazards.

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Compatibility

CRINA® Piglets is compatible with other commonly used feed additives such as enzymes, acidifiers, etc.

Packaging

CRINA® Piglets is available in 25kg pinch bottom bags with two external paper layers and one layer of polyethylene / aluminium / polyethylene on the inside.

Legislation

All compounds used in the CRINA® products are approved for food and appear on the FEMA/GRAS listing.

For EU countries, CRINA® Piglets complies with the current feed additive legislation (EEC 1831/2003) and the legislation concerning the undesirable substances and products in animal nutrition (Directive 1999/29/EEC as amended). CRINA® Piglets is classified as a ‘sensory additive’.

Supplier

DSM Nutritional Products (UK) Ltd Heanor Gate Heanor Derbyshire DE75 7SG

Tel: Fax: Website:

01773 536500 01773 536600 www.dsmnutritionalproducts.com

CRINA® is a registered trademark.

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CRINA® Poultry Presentation

CRINA® Poultry is a blend of flavouring compounds for animal nutrition. Appearance: Structure: Odour:

yellow to light brown free-flowing, non-dusty powder characteristic odour

CRINA® Poultry is a carefully balanced combination of essential oil compounds of high purity in their natural / nature-identical form on a carrier. Uses

CRINA® Poultry stimulates digestive functions and improves digestibility of nutrients. CRINA® Poultry helps to regulate gut microflora balance, thus maintaining healthy gut function and reduces intestinal disorders.

Recommended dosage

a) 100-150mg/kg of (pre) starter feed.

b) 50-100mg/kg of grower/finisher feed.

Stability

CRINA® Poultry is stable in premixes as well as in mash, pelleted or expanded feed. Stored in a dry place and at a temperature below 25°C in original unopened bags, CRINA® Poultry can be kept for up to one year after production. Prolonged storage at temperatures above 30°C should be avoided. The best used before date is printed on the label.

Keep container tightly closed. Once opened, contents should be used quickly. Avoid storage of CRINA® Poultry in plastic or plexiglass containers.

Palatability

At the recommended dosage CRINA® Poultry is readily accepted. At five times the recommended level feed refusal might be observed.

Precautions

Avoid unnecessary contact with the product or inhalation of dust. It is recommended to wear protective glasses and gloves when handling the product. In case of accidental access to non-target animals, CRINA® Poultry is safe and presents no hazards.

Compatibility

CRINA® Poultry is compatible with other commonly used feed additives such as enzymes, acidifiers, etc.

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Packaging:

CRINA® Poultry is available in 25kg pinch bottom bags with two external paper layers and one layer of polyethylene / aluminium / polyethylene on the inside.

Legislation

All compounds used in the CRINA® products are approved for food and appear on the FEMA/GRAS listing.

For EU countries, CRINA® Poultry complies with the current feed additive legislation (EEC 1831/2003) and the legislation concerning the undesirable substances and products in animal nutrition (Directive 1999/29/EEC as amended). CRINA® Poultry is classified as a ‘sensory additive’.

Supplier

DSM Nutritional Products (UK) Ltd Heanor Gate Heanor Derbyshire DE75 7SG

Tel: Fax: Website:

01773 536500 01773 536600 www.dsmnutritionalproducts.com

CRINA® is a registered trademark.

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CRINA® Ruminants Presentation

CRINA® Ruminants is a blend of flavouring compounds for animal nutrition. Appearance: Structure: Odour:

yellow to light brown free-flowing, non-dusty powder characteristic odour

CRINA® Ruminants is a carefully balanced combination of essential oil compounds of high purity in their natural / natureidentical form on a natural carrier. Uses

CRINA® Ruminants increases the by-pass of proteins and starch by modulating the rumen microbial population. These changes produce a number of effects in the rumen, which lead to better feed digestibility and utilisation.

Recommended dosage

Dairy cow: Beef cattle: Sheep and goats:

Stability

CRINA® Ruminants is stable in premixes as well as in mash, pelleted or expanded feed.

0.5-1.0g / head / day. 150-200mg / 100kg liveweight / day. 100mg / day.

Stored in a dry place and at a temperature below 25°C in original unopened bags, CRINA® Ruminants can be kept for up to one year after production. Prolonged storage at temperatures above 30°C should be avoided. The best used before date is printed on the label.

Keep container tightly closed. Once opened, contents should be used quickly. Avoid storage of CRINA® Ruminants in plastic or plexiglass containers.

Palatability

At the recommended dosage CRINA® Ruminants is readily accepted. At three times the recommended level feed refusal might be observed.

Precautions

Avoid unnecessary contact with the product or inhalation of dust. It is recommended to wear protective glasses and gloves when handling the product. In case of accidental access to non-target animals, CRINA® Ruminants is safe and presents no hazards.

Compatibility

CRINA® Ruminants is compatible with other commonly used feed additives such as enzymes, etc.

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Packaging

CRINA® Ruminants is available in 25kg pinch bottom bags with two external paper layers and one layer of polyethylene / aluminium / polyethylene on the inside.

Legislation

All compounds used in the CRINA® products are approved for food and appear on the FEMA/GRAS listing.

For EU countries, CRINA® Ruminants complies with the current feed additive legislation (EEC 1831/2003) and the legislation concerning the undesirable substances and products in animal nutrition (Directive 1999/29/EEC as amended). CRINA® Ruminants is classified as a ‘sensory additive’.

Supplier

DSM Nutritional Products (UK) Ltd Heanor Gate Heanor Derbyshire DE75 7SG

Tel: Fax: Website:

01773 536500 01773 536600 www.dsmnutritionalproducts.com

CRINA® is a registered trademark.

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Cycostat速 66 G Presentation

A greyish, dust-free, granular product for inclusion in animal feedingstuffs. Each kilogram of Cycostat 66G contains 66 grams robenidine hydrochloride.

Uses

As an aid in the prevention of coccidiosis in broiler chickens caused by Eimeria necatrix, E. tenella, E. acervulina, E. brunetti, E. maxima and E. mivati. As an aid in the prevention of coccidiosis in turkeys caused by Eimeria meleagrimitis, E. gallopavonis, E. adenoides and E. dispersa. As an aid in the prevention of coccidiosis in rabbits caused by Eimeria intestinalis, E. flavescens, E. magna, E. perforans and E. stiedae.

Dosage/administration

For oral administration as a feed additive, to be given in feedingstuffs by its thorough admixture with the feed (premix, supplement, concentrate or compound). Broiler chickens and turkeys: Mix 450-550g of Cycostat 66G per tonne of complete feed to supply 30-36 ppm robenidine hydrochloride. Rabbits: Mix 1kg Cycostat 66G per tonne of complete feed to supply 66 ppm robenidine hydrochloride. To help obtain uniform dispersion first thoroughly mix the required amount of Cycostat 66G with ten times its weight of feed or feed ingredients before blending into the final mix. Supply medicated feed only for the period during which birds or rabbits are at risk.

Contra-indications, warnings, etc.

For animal treatment only For use in feeds intended for broiler chickens, turkeys or rabbits only. Do not feed to laying hens. Clean all mixing equipment thoroughly before preparing other feedingstuffs. Cycostat 66G must not be mixed with or used simultaneously with feed containing any other anticoccidial or substance having a similar effect. Keep out of the reach of children.

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The product may only be mixed into feed by Category A manufacturers. Withdrawal period

Animals must not be slaughtered for human consumption during treatment. Broiler chickens, turkeys and rabbits may be slaughtered for human consumption only after five days from the last treatment.

Pharmaceutical precautions

Cycostat 66G and animal feedingstuffs containing Cycostat 66G should be stored under cool (below 25°C), dry conditions. Close the bag securely after use. Cycostat 66G is stable for up to 12 weeks in processed feed which is stored in cool, dry conditions.

Legal category

Specified feed additive (coccidiostat). (E758)

Package quantities

Available in multi-walled paper sacks in quantities of 20kg.

Marketing authorisation holder

Alpharma (Belgium) BVBA Garden Square Laarstraat 16 B-2610 Antwerp Belgium

Tel: Fax: Website:

+32 (0) 3 287 3880 +32 (0) 3 287 3881 www.alpharmaah.com

UK representative

Tel:

+44 (0) 7740 483818

CycostatÂŽ is a registered trade mark of Alpharma Inc, Bridgewater, USA

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CygroÂŽ 1%

â&#x2014;&#x160;

Presentation

Moderately fine, light tan, free-flowing granules for inclusion in animal feedingstuffs. Each kg of Cygro 1% contains 10g maduramicin ammonium

Uses

As an aid in the prevention of coccidiosis in broiler chickens caused by Eimeria necatrix, E. tenella, E. acervulina, E. brunetti, E. maxima and E. mivati. As an aid in the prevention of coccidiosis in turkeys caused by Eimeria meleagrimitis, E. gallopavonis, E. adenoides, and E. dispersa.

Dosage/administration

Use feed containing Cygro 1% as the only feed for the period during which chickens and turkeys are at risk. Cygro 1% should be mixed thoroughly into feeds at a level of 500g per tonne. This will provide 5mg maduramicin ammonium/kg. To optimise blending, Cygro 1% should be diluted at least 1 to 10 with supplement or feed ingredient prior to incorporation into the final mix.

Contra-indications, warnings, etc.

For animal treatment only. For use in feeds intended for chickens and turkeys only. Cygro 1% must not be mixed with or used simultaneously with feed containing another anticoccidial. Direct contact with the skin is to be avoided. When mixing and handling Cygro 1%, use protective clothing, impervious gloves and a dust mask. Operators should wash thoroughly with soap and water after handling Cygro 1% . If accidental eye contact occurs, rinse thoroughly with water. Keep out of the reach of children. Do not allow horses or other equines access to feeds containing this product. Ingestion of maduramicin ammonium may be fatal.

Withdrawal period

Animals must not be slaughtered for human consumption during treatment. Broiler chickens and turkeys may be slaughtered for human consumption only after five days from the last treatment.

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Pharmaceutical precautions

Store below 25°C in dry conditions. Close the bag securely after use. Under normal circumstances the product when undergoing processing in the final feed will tolerate preconditioning at temperatures of up to 90°C for up to 30 minutes. Cygro 1% will be stable for up to 12 weeks in processed feed when stored in cool, dry conditions.

◊ Legal category

Specified feed additive (coccidiostat) (E770).

Package quantities

Available in multi-walled paper sacks in quantities of 20kg.

Further information

When used as recommended, Cygro 1% should only be incorporated by a Category A manufacturer. Mixture of maduramicin ammonium with bentonite/montmorillonite is allowed.

Supplier

Alpharma (Belgium) BVBA Garden Square Laarstraat 16 B-2610 Antwerp Belgium

Tel: Fax: Website:

+32 (0) 3 287 3880 +32 (0) 3 287 3881 www.alpharmaah.com

UK representative

Tel:

+44 (0) 7740 483818

®Registered trademark of Alpharma Inc, Bridgewater, USA

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Cylactin® LBC ME10 Presentation

White to light-yellow granules for inclusion in animal feedingstuffs. Each gram contains not less than 10 x 109 colony forming units of Enterococcus faecium Cernelle 68 (SF68; NCIMB 10415).

Uses

Cylactin may be used as an aid in the establishment, maintenance and restoration of a balanced gut flora in pigs, calves and broiler chickens.

Dosage/administration

Cylactin is recommended for use at the following rates:

Species

Cylactin LBC ME10 (g/t feed or milk replacer)

Recommended Dose (CFU/kg feed)

Piglets up to 4 months

70g/t

0.7 x 109

Pigs for fattening

35g/t

0.35 x 109

Sows (two weeks pre-farrowing to end of lactation)

70g/t

0.7 x 109

Calves (max. 6 months)

140g/t

1.4 x 109

Broiler chickens

35g/t

0.35 x 109

May be used in compound feed containing the following permitted coccidiostats: amprolium, amprolium/ethopabate, diclazuril, halofuginone, maduramicin ammonium, metaclorpindol, metaclorpindol/methylbenzoquate, monensin sodium, robenidine, salinomycin sodium. Contra-indications, warnings, etc.

For animal treatment only. Avoid ingestion, inhalation or direct contact by applying suitable protective measures and personal hygiene. If accidental eye contact occurs, rinse thoroughly with water. Keep out of the reach of children. The product will remain stable for two years when stored in a dry place at a temperature of between 2 and 8°C. When stored at 25°C, the maximum storage time before inclusion in feed should be reduced to five months. Single pelleting at temperatures below 85°C is acceptable. However, heat treatment prior to pelleting, double pelleting and pelleting at temperatures over 85°C may be detrimental to the stability of the product.

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The product will remain stable in feeds for three months when stored in dry conditions at room temperature. When stored at high temperatures the product shall be used within five months. Additive functional group

Gut flora stabiliser.

Package quantities

Available in pails in quantities of 10 and 25kg.

Further information

E. faecium is a normal inhabitant of the intestines of humans and animals. The SF68 strain was specially selected for its capacity to resist the acid conditions as it passes through the stomach, its ability to colonise and multiply in the small intestine and its production of lactic acid. The presence of sufficient numbers helps to stabilise the microbial population so that the environment of the gut is more acid and less hospitable to potentially harmful bacteria such as Escherichia coli, Clostridia and Salmonella. This can have a positive impact on the health status of the gut, enabling it to function optimally, even in the young animal with an immature digestive system. For optimal efficacy, the live bacteria in Cylactin have been protected in a special process of microencapsulation. This helps to minimise damage to the bacteria during feed manufacture and storage.

EU authorisation

Cylactin速 LBC ME10 is permanently approved for calves, chickens for fattening, piglets, pigs for fattening and sows as E1705.

Supplier

DSM Nutritional Products (UK) Ltd Heanor Gate Heanor Derbyshire DE75 7SG

Tel: Fax: Website:

速Registered trademark

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01773 536500 01773 536600 www.dsmnutritionalproducts.com

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Deccox® 6% Presentation

Buff-coloured powder containing 60g Decoquinate BP (Vet) per kilogramme

Uses

For treatment and prophylaxis of coccidiosis in lambs and calves during coccidial challenge, by medication of the feed. As an aid in the control of coccidiosis in lambs, by medication of ewe feed. As an aid in the prevention of abortions and perinatal losses due to toxoplasmosis by medication of ewe feed.

Dosage/administration

Treatment of coccidiosis in lambs and calves, and prevention of coccidiosis in lambs: Add 1.67kg of premix per tonne of feed, to provide the recommended concentration of 100mg decoquinate/kg feed (100 ppm). If creep feed is provided to lambs on a restricted basis (e.g. less than 100g/10kg bodyweight daily) or calves are fed at less than the recommended feeding rate of 500g/50kg bodyweight daily, the rate at which Deccox® 6% is included in feed should be raised proportionally to achieve the target intake of approximately 1mg decoquinate/kg bodyweight daily. For example: Daily feeding rate Rate of inclusion Lambs Calves of Deccox (feed/bodyweight) (feed/bodyweight) (kg/tonne)

100g/10kg

500g/50kg

1.67kg/tonne

75g/10kg

375g/50kg

2.22kg/tonne

50g/10kg 250g/50kg 3.34kg/tonne Feed continuously for 28 days when coccidiosis is expected to be a risk. Medication may be continued if there is further risk beyond this period. Prevention of coccidiosis in calves, and as an aid in prevention of coccidiosis in lambs by medication of the ewe’s feed: Add 833g of premix per tonne of feed to provide the recommended concentration of 50mg decoquinate/kg of feed (50 ppm).

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If ewe or calf feed is provided on a restricted basis (e.g. less than 500g/50kg bodyweight daily), the concentration of Deccox速 6% should be raised proportionally, to achieve the target intake of approximately 0.5mg decoquinate/kg bodyweight daily. Feed continuously for at least 28 days to ewes when oocyst shedding is likely to be a risk to lambs (i.e. before, during or after lambing), or to calves when coccidiosis is likely to occur. The above provides good control of oocyst shedding from ewes under most conditions. In cases where more severe challenge exists, double dosage should be used. As an aid in the prevention of abortions and perinatal losses due to toxoplasmosis by medication of ewe feed: For use during pregnancy. Administer medicated feed at a rate to provide the target intake of 2.0mg decoquinate/kg bodyweight daily, according to the rate at which Deccox速 6% has been included in the ration. Two examples which achieve the recommended dosage of 2.0mg decoquinate/kg are shown below: 1. Mid pregnancy Add 6.68kg of premix per tonne; feed at 250g/50kg bodyweight daily. 2. Late pregnancy Add 3.34kg of premix per tonne; feed at 500g/50kg bodyweight daily. If ewes are to be fed at other rates, the rate of inclusion of Deccox速 6% in the feed should be adjusted accordingly. Medicated feed should be labelled with the feeding rate required to achieve the target intake of decoquinate. Feed continuously for the last two-thirds of pregnancy (i.e. for the final 14 weeks before lambing). Contra-indications, warnings, etc.

For animal treatment only. Keep out of the reach of children. Not for use in sheep or cattle when their milk is intended for human consumption. The use of the product will maintain normal growth under conditions of coccidial challenge but does not improve growth of healthy lambs or calves. Medication of ewe rations alone may not prevent coccidiosis occuring in lambs and should be given only in conjunction with lamb medication. Do not mix with or into feeds containing any other anticoccidial. When handling Deccox速 6%, prevent its direct contact with the skin, avoid inhaling dust and wash hands after use.

Withdrawal period

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Zero days.

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Pharmaceutical precautions

To help ensure thorough dispersion of Deccox® 6% in feed, one part of Deccox® 6% should be mixed with three parts of the feed before incorporation into the final mix. Deccox® 6% may be incorporated into pelleted feed preconditioned for up to ten minutes at a temperature not greater than 80°C. Deccox® 6% will remain stable in finished feed for three months.

Legal category

POM-V

Package quantity

10kg

Further information

On farms with a history of toxoplasmosis abortions, it may be economically beneficial to segregate susceptible ewes (e.g. bought-in ewe lambs) and administer medicated feed only to these animals, as the majority of older ewes will have been previously exposed to toxoplasma infection and will therefore be immune.

Marketing authorization number

Vm 21766/4003

Marketing authorization holder and marketed by

Alpharma BVBA, Garden Square Laarstraat 16 B-2610 Antwerp Belgium Tel: Website:

+44 (0) 7717 345108 www.alpharmaah.com

Deccox® is a Registered Trade Mark of Alpharma Inc, Bridgewater, USA

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Denagard 2% Premix Presentation

Denagard 2% Premix is a free-flowing formulation consisting of tiamulin hydrogen fumarate in a maize starch carrier for administration in the feed to pigs. Denagard 2% Premix contains 20g tiamulin hydrogen fumarate per kg.

Uses

Actions: The following organisms show sensitivity to tiamulin hydrogen fumarate in vitro: Brachyspira: Brachyspira hyodysenteriae, B. pilosicoli. Mycoplasmas: Mycoplasma hyopneumoniae, M.hyorhinis, M.hyosynoviae, Ureaplasma spp. Gramâ&#x20AC;&#x2018;positive: Staphylococcus spp., Streptococcus spp., Arcanobacterium pyogenes. Gram negative: Pasteurella spp., Klebsiella pneumoniae, Actinobacillus (Haemophilus) spp., Fusobacterium necrophorum, Bacteroides spp., Campylobacter coli, Lawsonia intracellularis. Indications: For the treatment, prevention and control of swine dysentery caused by Brachyspira hyodysenteriae and complicated by Fusobacterium spp. and Bacteroides spp. For the treatment and control of ileitis due to Lawsonia intracellularis. For the treatment of colitis due to B. pilosicoli. As an aid in the control of the enzootic pneumonia complex in pigs. Denagard should be used when a diagnosis of the indicated disease has been established in the herd.

Dosage/administration

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For the treatment and control of ileitis: The dose is 7.5mg tiamulin hydrogen fumarate per kg bodyweight daily, administered for 14 days. An inclusion rate of 7.5kg of Denagard 2% Premix (equivalent to 150g tiamulin hydrogen fumarate) per tonne of feed should provide this dose in growing pigs.

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For the treatment of clinical swine dysentery and colitis: The dose is 5mg tiamulin hydrogen fumarate per kg bodyweight daily, administered for 7 to 10 days. An inclusion rate of 5kg Denagard 2% Premix (equivalent to 100g tiamulin hydrogen fumarate) per tonne of feed should provide this dose in growing pigs. Following recovery, continue medication at the preventative level to prevent recurrence of the disease. For the control and prevention of swine dysentery: The dose is 1.5‑2.0mg tiamulin hydrogen fumarate per kg bodyweight, administered throughout the period of risk to control re‑infection. An inclusion rate of 1.5‑2.0kg Denagard 2% Premix (equivalent to 30‑40g tiamulin hydrogen fumarate) per tonne of feed should provide this dose in growing pigs. Feed throughout the period of risk to control re‑infection. As an aid in the control of the enzootic pneumonia complex in pigs: The dose is 1.5‑2.0mg tiamulin hydrogen fumarate per kg bodyweight daily administered for up to two months during the period of risk. An inclusion rate of 1.5‑2.0kg Denagard 2% Premix (equivalent to 30‑40g tiamulin hydrogen fumarate) per tonne of feed should provide this dose in growing pigs. Inclusion Rates: When medicating larger pigs including breeding animals or where inappetance occurs, the inclusion level may need adjusting as follows to give the correct dose. Example: Dose: 2mg tiamulin hydrogen fumarate per kg bodyweight Average pig bodyweight (kg) x 2mg =

g tiamulin hydrogen

Average daily feed intake (kg)

fumarate/tonne feed

Dose: 5mg tiamulin hydrogen fumarate per kg bodyweight Average pig bodyweight (kg) x 5mg =

g tiamulin hydrogen

Average daily feed intake (kg)

fumarate/tonne feed

When mixing small quantities, it is advisable to hand‑mix the required amount of premix into approximately 20kg of feed or feed supplement prior to mixing into the complete feed.

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Contra-indications, warnings, etc.

For animal treatment only. Warning: Animals must not be slaughtered for human consumption during treatment. Pigs may be slaughtered for human consumption only after the time indicated in the table below from the last treatment.

Indications

Dose

Duration

Meat Withdrawal Period

Control and prevention of swine dysentery

1.5-2.0mg tiamulin hydrogen fumarate per kg bodyweight (c. 30-40 ppm in feed)

For the period of risk

24 hours

As an aid in the control of enzootic pneumonia complex in pigs

1.5-2.0mg tiamulin hydrogen fumarate per kg bodyweight (c. 30-40 ppm in feed)

Up to two months during period of risk

24 hours

Treatment of clinical swine dysentery and colitis

5.0mg tiamulin hydrogen fumarate per kg bodyweight (c. 100 ppm in feed)

7 to 10 days

4 days

Treatment and control of ileitis

7.5mg tiamulin hydrogen fumarate per kg bodyweight (c. 150 ppm in feed)

14 days

4 days

To be used in pig rations only. Animals should not receive products containing monensin, narasin or salinomycin, during or for at least seven days before or after treatment with tiamulin at the 100g per tonne (equivalent to a 5mg/kg bodyweight) daily dose. Severe growth depression or death may result. Studies have shown that at tiamulin inclusion levels of 3040g/tonne (equivalent to 1.5-2.0mg/kg bodyweight daily), no interaction occurs between salinomycin at 60g per tonne of feed or monensin at 100g per tonne of feed. Interaction has been observed between tiamulin at 30-40g per tonne in feed and narasin at 70g per tonne of feed.

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Operator Warnings Caution: When mixing, direct contact with the skin and eyes should be avoided by wearing impermeable rubber gloves and safety glasses. In case of accidental eye contact, irrigate the eyes thoroughly with clean running water immediately. Seek medical advice if irritation persists. When handling the product, inhalation of the dust must be avoided by wearing a disposable half-mask respirator conforming to European Standard EN149 or a non-disposable respirator to European Standard EN140 with a filter to EN143. Contaminated clothing should be removed and any splashes on to the skin should be washed off immediately. Wash hands after use. Precaution: On rare occasions erythema or mild oedema of the skin may occur in pigs following the use of tiamulin hydrogen fumarate. If there is no response to treatment within five days, the diagnosis should be re-established. Severely affected pigs showing inappetence should be medicated with Denagard 12.5% Oral Solution or Denagard 200 Solution for Injection. Keep out of the reach of children. Pharmaceutical precautions

Store below 25째C in a dry place. Protect from light.

Denagard 2% Premix will remain stable in the finished feed or vitamin/mineral premixes for eight weeks.

Shelf life: four years.

To ensure thorough dispersion, the product should first be mixed with a suitable quantity of feed ingredients before incorporation into the final mix. Disposal

Dispose of any unused product and empty containers in accordance with guidance from your local waste regulation authority.

Legal category

POM-V

Package quantities

5kg laminated paper sacks with polyethylene inner layer.

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Further information

Studies have shown that 30-40g tiamulin hydrogen fumarate per tonne of feed will reduce production losses associated with enzootic pneumonia. A reduction in clinical disease incidence or severity may not necessarily be seen. Attention should be paid to ventilation and stocking density in conjunction with medication. Good milling and mixing procedures should be followed when mixing feeds containing Denagard 2% Premix. If this product is incorporated in an intermediate feedingstuff, care should be taken to ensure that the intermediate feedingstuff is incorporated at a rate which will yield the same concentration of active ingredient in the final feed as stated in the POM-V prescription. The product is compatible with recommended doses of chlortetracycline and tylosin. A Category A manufacturer must be responsible for mixing when incorporation is less than 2kg per tonne of final feed.

Marketing authorisation number

Vm 12501/4067.

Marketing authorisation holder

Novartis Animal Health UK Ltd

Marketed and distributed by

Novartis Animal Health UK Ltd Frimley Business Park Frimley Camberley Surrey GU16 7SR

Tel: 01276 694402

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Handbook of Feed Additives 2009 Handbook of Feed Additives 2009 is one of several directories, periodicals and reports published by Simon Mounsey Ltd. Amongst our other titles for feed producers and their suppliers are: • Feed Statistics 2009 • Feed Businesses 2009 • Feed Industry Review Details about these and other publications and services can be found on our website at: www.simonmounsey.com

Updates to this Handbook can also be found on the same website. You can go directly to the updates site at the following address: www.simonmounsey.com/hbupdate.htm

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Denagard 10% Premix new Presentation

Denagard 10% Premix is a free-flowing white to cream, grey-tinged powder consisting of gel-coated tiamulin hydrogen fumarate in a maize starch carrier for administration in the feed to pigs. Denagard 10% Premix contains 100g tiamulin hydrogen fumarate per kg.

Uses

Actions: Tiamulin hydrogen fumarate is a semi-synthetic diterpene antibiotic. The mode of action is by inhibition of ribosomal protein synthesis in sensitive bacteria. It is a bacteriostatic antibiotic and the following organisms show sensitivity in vitro: Brachyspira: Brachyspira hyodysenteriae, Brachyspira pilosicoli. Mycoplasmas: Mycoplasma hyopneumoniae, M.hyorhinis, M.hyosynoviae, Ureaplasma spp. Gram‑positive: Staphylococcus spp., Streptococcus spp., Corynebacterium pyogenes. Gram negative: Pasteurella spp., Klebsiella pneumoniae, Actinobacillus (Haemophilus) spp., Fusobacterium necrophorum, Bacteroides spp., Campylobacter coli, Lawsonia intracellularis. Indications: For the treatment, prevention and control of swine dysentery caused by Brachyspira hyodysenteriae and complicated by Fusobacterium spp. and Bacteroides spp. As an aid in the control of the enzootic pneumonia complex in pigs.

Dosage/administration

For the treatment of clinical swine dysentery: The dose is 5mg tiamulin hydrogen fumarate per kg bodyweight daily, administered for 7 to 10 days. An inclusion rate of 1kg Denagard 10% Premix (equivalent to 100g tiamulin hydrogen fumarate) per tonne of feed should provide this dose in growing pigs. Following recovery, continue medication at the preventative level to prevent recurrence of the disease. For the control and prevention of swine dysentery: The dose is 1.5‑2.0mg tiamulin hydrogen fumarate per kg bodyweight, administered throughout the period of risk to control re‑infection. An inclusion rate of 300-400g Denagard 10% Premix (equivalent to 30‑40g tiamulin hydrogen fumarate) per tonne of feed should provide this dose in growing pigs. Feed throughout the period of risk to control re‑infection.

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As an aid in the control of the enzootic pneumonia complex in pigs: The dose is 1.5‑2.0mg tiamulin hydrogen fumarate per kg bodyweight daily administered for up to two months during the period of risk. An inclusion rate of 300-400g Denagard 10% Premix (equivalent to 30‑40g tiamulin hydrogen fumarate) per tonne of feed should provide this dose in growing pigs. Inclusion Rates: To ensure a correct dosage, bodyweight of the pigs should be determined as accurately as possible to avoid underdosing. The uptake of medicated feed depends on the clinical condition of the animals. In order to obtain the correct dosage the concentration of Denagard 10% Premix should be adjusted accordingly. When medicating larger pigs including breeding animals or where inappetance occurs, the inclusion level may need adjusting as follows to give the correct dose. Example: Dose: 2mg tiamulin hydrogen fumarate per kg bodyweight Average pig bodyweight (kg) x 2mg =

g tiamulin hydrogen

Average daily feed intake (kg)

fumarate/tonne feed

Dose: 5mg tiamulin hydrogen fumarate per kg bodyweight Average pig bodyweight (kg) x 5mg =

g tiamulin hydrogen

Average daily feed intake (kg)

fumarate/tonne feed

Care should be taken that the intended dose is completely ingested. Acute cases and severely diseased pigs with reduced food or water intake should be treated with a suitable injectable product. To ensure thorough dispersion, the product should first be mixed with a suitable quantity of feed ingredients before incorporation into the final mix. The product can be incorporated into pelleted feed at a temperature not exceeding 80°C. Contra-indications, warnings, etc.

Animals should not receive products containing monensin, narasin or salinomycin, during or for at least seven days before or after treatment with tiamulin at the 100g per tonne (equivalent to a 5mg/kg bodyweight) daily dose. Severe growth depression or death may result.

Studies have shown that 30-40g per tonne of feed tiamulin hydrogen fumarate in the feed will reduce production losses associated with enzootic pneumonia. A reduction in clinical

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disease incidence or severity may not necessarily be seen. Attention should be paid to ventilation and stocking density in conjunction with medication. If this product is incorporated in an intermediate feedingstuff care should be taken to ensure that the intermediate feedingstuff is incorporated at a rate which will yield the same concentration of active ingredient in the final feed as stated in the Medicated Feedingstuffs (MFS) Prescription. The product is compatible with recommended doses of chlortetracyline and tylosin.

To be used in pig rations only. Use of the product should be based on susceptibility testing of the bacteria from previous cases and it should take into account official and local antimicrobial policies. If there is no clinical improvement within two to three days a new susceptibility test with a possible change in therapy may be considered necessary. Tiamulin should not be used to compensate for poor hygiene and management of the pig unit.

Precaution: On rare occasions erythema or mild oedema of the skin may occur in pigs following the use of tiamulin hydrogen fumarate.

Use in pregnancy and lactation: Suitable for use in pigs during pregnancy and lactation.

Overdosage: Pleuromutilins show a wide margin of safety.

Studies have shown that at tiamulin hydrogen fumarate inclusion levels of 30-40g per tonne (equivalent to 1.5-2.0mg/ kg bodyweight daily) no interaction occurs with salinomycin at 60g per tonne of feed or monensin at 100g per tonne of feed. Interaction has been observed between tiamulin hydrogen fumarate at 30-40g per tonne in feed and narasin, at 70g per tonne of feed.

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Withdrawal periods: Animals must not be slaughtered for human consumption during treatment. Withdrawal periods for the different dosing regimes are:

Indications

Dose

Duration

Meat Withdrawal Period

Control and prevention of swine dysentery

1.5-2.0mg tiamulin hydrogen fumarate per kg bodyweight (c. 30-40 ppm in feed)

For the period of risk

24 hours

As an aid in the control of enzootic pneumonia complex in pigs

1.5-2.0mg tiamulin hydrogen fumarate per kg bodyweight (c. 30-40 ppm in feed)

Up to two months during period of risk

24 hours

Treatment of clinical swine dysentery

5.0mg tiamulin hydrogen fumarate per kg bodyweight (c. 100 ppm in feed)

7 to 10 days

4 days

Operator Warnings Caution: When mixing, direct contact with the skin and eyes should be avoided by wearing impermeable rubber gloves and safety glasses. In case of accidental eye contact, irrigate the eyes thoroughly with clean running water immediately. Seek medical advice if irritation persists. When handling the product, inhalation of the dust must be avoided by wearing a disposable half-mask respirator conforming to European Standard EN149 or a non-disposable respirator to European Standard EN140 with a filter to EN143. Contaminated clothing should be removed and any splashes on to the skin should be washed off immediately. Wash hands after use. Pharmaceutical precautions

Storage: Protect from direct sunlight.

Shelf life: Denagard 10% Premix will remain stable in its unopened packaging for four years. Shelf life after opening: 12 weeks Shelf life when incorporated into meal feed: 8 weeks Shelf life when incorporated into pelleted feed: 8 weeks

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Legal category

POM-V

Package quantities

1kg, 5kg and 25kg laminated paper sacks with inner layer of LDPE.

Further information

Following oral administration, tiamulin hydrogen fumarate is rapidly absorbed and peak serum concentrations are achieved 2-4 hours after administration as are concentrations in some tissues, e.g. lung. Following administration, it is rapidly metabolised and excreted.

Disposal

Any unused product or waste material should be disposed of in accordance with national requirements.

Marketing authorisation number

Vm 12501/4163

Marketing authorisation holder

Novartis Animal Health UK Ltd

Marketed and distributed by

Novartis Animal Health UK Ltd Frimley Business Park Frimley Camberley Surrey GU16 7SR

Tel: 01276 694402

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Denagard 12.5% Oral Solution Presentation

An aqueous solution containing 125mg tiamulin hydrogen fumarate per ml. Denagard 12.5% Oral Solution also contains methylparahydroxybenzoate (0.9mg/ml) and propylparahydroxybenzoate (0.1mg/ml) as preservatives.

Uses

Actions: The following organisms show sensitivity to tiamulin hydrogen fumarate in vitro: Brachyspira: Brachyspira hyodysenteriae, B.pilosicoli. Mycoplasmas: Mycoplasma hyopneumoniae, M.hyorhinis, M.hyosynoviae, Ureaplasma spp., M.gallisepticum, M.synoviae, M.meleagridis. Gramâ&#x20AC;&#x2018;positive: Staphylococcus spp., Streptococcus spp., Arcanobacterium pyogenes. Gram negative: Pasteurella spp., Klebsiella pneumoniae, Actinobacillus (Haemophilus) spp., Fusobacterium necrophorum, Bacteroides spp., Campylobacter coli, Lawsonia intracellularis. Indications: Pigs For the treatment, prevention and control of swine dysentery caused by Brachyspira hyodysenteriae and complicated by Fusobacterium spp. and Bacteroides spp. Chickens For the reduction in severity of disease caused by mycoplasmas. Turkeys For the reduction in severity of disease caused by mycoplasmas.

Dosage/administration

Pigs The dosage is 8.8mg of the active substance per kg bodyweight daily (equivalent to 10ml Denagard 12.5% Oral Solution per 142kg bodyweight) administered in the drinking water of pigs for 3 to 5 days, depending on the severity of the infection and/or the duration of the disease. The contents of each one litre bottle will treat 188 pigs of 25kg bodyweight for three days or 114 pigs of 25kg bodyweight for five days.

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To ensure an intake of 8.8mg/kg daily, Denagard 12.5% Oral Solution may be administered in one of two ways: (i) Denagard 12.5% Oral Solution may be administered in approximately one half of the daily water requirements, to ensure consumption of the correct dose. Unmedicated water should be provided each day after the medicated water has been consumed. The dosage rate, calculated on a liveweight basis, is equivalent to 10ml solution per 142kg bodyweight. (ii) Tiamutin may be administered continuously in the drinking water at a level of 60ppm of active substance in the drinking water, as the only source of drinking water. The daily requirement should be added to the drinking water at the rate of 9.6ml Solution per 20 litres (4.5 gallons) of water. Where a water medicator is used, the appropriate stock solution should be made up according to the makerâ&#x20AC;&#x2122;s instructions. If there is no response to treatment within five days, the diagnosis should be re-established. Chickens The dosage for chickens is 25mg of active substance per kg bodyweight (equivalent to 100ml of product per 500kg bodyweight). Tiamulin should be administered continuously at a level of 0.025% (250ppm) in drinking water (2ml product per litre of water) for 3-5 days and will provide approximately the following dosage of tiamulin depending on the age of the bird: Day old chick: 4 week old pullet: 10 week old pullet: Layer:

125-150mg/kg bodyweight 30-50mg/kg bodyweight 30-45mg/kg bodyweight 25mg/kg bodyweight

Turkeys The dosage for turkeys is 25mg of active substance per kg bodyweight (equivalent to 100ml of product per 500kg bodyweight). Tiamulin should be administered continuously at a level of 0.025% (250ppm) in drinking water (2ml product per litre of water) for five days and will provide approximately the following dosage of tiamulin depending on the age of the bird: 1 week old poult: 4 week old poult: 8 week old poult: 20 week old poult:

70mg/kg bodyweight 50mg/kg bodyweight 25-30mg/kg bodyweight 25mg/kg bodyweight

Monitor water intake at frequent intervals during medication. Fresh solutions of tiamulin-medicated water should be made up each day.

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Contra-indications, warnings, etc.

For animal treatment only. Do not use in animals hypersensitive to the active ingredient. Warning: Animals and birds must not be slaughtered for human consumption during treatment. Pigs may be slaughtered for human consumption only after two days from the last treatment. Chickens may be slaughtered for human consumption only after two days from the last treatment. Nil withdrawal period for eggs. Turkeys may be slaughtered for human consumption only after five days from the last treatment. For use in the drinking water of pigs, chickens and turkeys only. Animals should not receive products containing monensin, narasin or salinomycin during or for at least seven days before or after treatment with Denagard 12.5% Oral Solution. Severe growth depression or death may result.

Operator warnings

Caution: When mixing, direct contact with the skin should be avoided. Any splashes on the skin should be washed off immediately. Pregnancy and lactation: Denagard is suitable for use during pregnancy and lactation. Tiamulin may be used in laying and breeding birds as it has been shown to have no adverse effects on egg production, fertility and hatchability in chickens and turkeys. Precautions: If there is no response to treatment within five days, the diagnosis should be re-established. Severely affected pigs that do not drink should be treated with Denagard 200 Solution for Injection. On rare occasions erythema or mild oedema of the skin may occur in pigs following the use of tiamulin hydrogen fumarate. Water intake may be depressed during the administration of tiamulin to birds. It appears to be concentration dependent with 0.025% (250ppm) tiamulin reducing intake by approximately 15%. It does not appear to have any adverse effect on overall performance of the birds or efficacy of the product. Keep out of the reach of children.

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Pharmaceutical precautions

Store below 25째C. Fresh medicated water must be prepared every 24 hours. Watering equipment should be thoroughly cleaned prior to addition of Denagard 12.5% Oral Solution.

Disposal: Dispose of any unused product and empty containers in accordance with guidance from your local waste regulation authority.

Legal category

POM-V

Package quantities

1 litre dispensing pack.

Marketing authorisation number

Vm 12501/4080

Marketing authorisation holder

Novartis Animal Health UK Ltd

Marketed and distributed by

Novartis Animal Health UK Ltd Frimley Business Park Frimley Camberley Surrey GU16 7SR

Tel: 01276 694402

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Presentation

Denagard 80% Premix

Denagard 80% Premix is a free-flowing formulation consisting of gel-coated tiamulin hydrogen fumarate in a carrier for administration in the feed to pigs. Denagard 80% Premix contains 800g tiamulin hydrogen fumarate per kg.

Uses

Actions: The following organisms show sensitivity to tiamulin hydrogen fumarate in vitro: Brachyspira: Brachyspira hyodysenteriae, Brachyspira pilosicoli. Mycoplasmas: Mycoplasma hyopneumoniae, M.hyorhinis, M.hyosynoviae, Ureaplasma spp., M.gallisepticum, M.synoviae, M.meleagridis. Gram‑positive: Staphylococcus spp., Streptococcus spp., Arcanobacterium pyogenes. Gram negative: Pasteurella spp., Klebsiella pneumoniae, Actinobacillus (Haemophilus) spp., Fusobacterium necrophorum, Bacteroides spp., Campylobacter coli, Lawsonia intracellularis. Indications: For the treatment, prevention and control of swine dysentery caused by Brachyspira hyodysenteriae and complicated by Fusobacterium spp. and Bacteroides spp. As an aid in the control of the enzootic pneumonia complex in pigs.

Dosage/administration

For the treatment of clinical swine dysentery: The dose is 5mg tiamulin hydrogen fumarate per kg bodyweight daily, administered for 7 to 10 days. An inclusion rate of 125g Denagard 80% Premix (equivalent to 100g tiamulin hydrogen fumarate) per tonne of feed should provide this dose in growing pigs. Following recovery, continue medication at the preventative level to prevent recurrence of the disease. For the control and prevention of swine dysentery: The dose is 1.5‑2.0mg tiamulin hydrogen fumarate per kg bodyweight, administered throughout the period of risk to control re‑infection. An inclusion rate of 37.5-50g Denagard 80% Premix (equivalent to 30‑40g tiamulin hydrogen fumarate) per tonne of feed should provide this dose in growing pigs. Feed throughout the period of risk to control re‑infection.

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As an aid in the control of the enzootic pneumonia complex in pigs: The dose is 1.5‑2.0mg tiamulin hydrogen fumarate per kg bodyweight daily administered for up to two months during the period of risk. An inclusion rate of 37.5-50g Denagard 80% Premix (equivalent to 30‑40g tiamulin hydrogen fumarate) per tonne of feed should provide this dose in growing pigs. Inclusion Rates: When medicating larger pigs including breeding animals or where inappetance occurs, the inclusion level may need adjusting as follows to give the correct dose. Example: Dose: 2mg tiamulin hydrogen fumarate per kg bodyweight Average pig bodyweight (kg) x 2mg =

g tiamulin hydrogen

Average daily feed intake (kg)

fumarate/tonne feed

Dose: 5mg tiamulin hydrogen fumarate per kg bodyweight Average pig bodyweight (kg) x 5mg =

g tiamulin hydrogen

Average daily feed intake (kg)

fumarate/tonne feed

When mixing small quantities, it is advisable to hand‑mix the required amount of premix into approximately 20kg of feed or feed supplement prior to mixing into the complete feed. Contra-indications, warnings, etc.

For animal treatment only. Warning: Animals must not be slaughtered for human consumption during treatment. Pigs may be slaughtered for human consumption only after the time indicated in the table below from the last treatment.

Indications

Dose

Duration

Meat Withdrawal Period

Control and prevention of swine dysentery

1.5-2.0mg tiamulin hydrogen fumarate per kg bodyweight (c. 30-40 ppm in feed)

For the period of risk

24 hours

As an aid in the control of enzootic pneumonia complex in pigs

1.5-2.0mg tiamulin hydrogen fumarate per kg bodyweight (c. 30-40 ppm in feed)

Up to two months during period of risk

24 hours

Treatment of clinical swine dysentery

5.0mg tiamulin hydrogen fumarate per kg bodyweight (c. 100 ppm in feed)

7 to 10 days

4 days

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To be used in pig rations only. Animals should not receive products containing monensin, narasin or salinomycin, during or for at least seven days before or after treatment with tiamulin at the 100g per tonne (equivalent to a 5mg/kg bodyweight) daily dose. Severe growth depression or death may result. Interaction has been observed between tiamulin at 30-40g per tonne in feed and narasin at 70g per tonne in feed. Operator Warnings Caution: When mixing, direct contact with the skin and eyes should be avoided by wearing impermeable rubber gloves and safety glasses. In case of accidental eye contact, irrigate the eyes thoroughly with clean running water immediately. Seek medical advice if irritation persists. When handling the product, inhalation of the dust must be avoided by wearing a disposable half-mask respirator conforming to European Standard EN149 or a non-disposable respirator to European Standard EN140 with a filter to EN143. Contaminated clothing should be removed and any splashes on to the skin should be washed off immediately. Wash hands after use. Precaution: On rare occasions erythema or mild oedema of the skin may occur in pigs following the use of tiamulin hydrogen fumarate. If there is no response to treatment within five days, the diagnosis should be re-established. Severely affected pigs showing signs of inappetance should be medicated with Denagard 12.5% Oral Solution or Denagard 200 Solution for Injection. Keep out of the reach of children.

Pharmaceutical precautions

Do not store above 25째C. Store in a dry place. Protect from light. Denagard 80% Premix will remain stable in the finished feed or vitamin/mineral premixes for three months. To ensure thorough dispersion, the product should first be mixed with a suitable quantity of feed ingredients before incorporation into the final mix.

Legal category

POM-V

Package quantities

5kg and 25kg polyethylene bags.

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Further information

Studies have shown that 30-40g tiamulin hydrogen fumarate per tonne of feed will reduce production losses associated with enzootic pneumonia. A reduction in clinical disease incidence or severity may not necessarily be seen. Attention should be paid to ventilation and stocking density in conjunction with medication. Good milling and mixing procedures should be followed when mixing feeds containing Denagard 80% Premix. If this product is incorporated in an intermediate feedingstuff, care should be taken to ensure that the intermediate feedingstuff is incorporated at a rate which will yield the same concentration of active ingredient in the final feed as stated in the POM-V prescription. The product is compatible with recommended doses of chlortetracycline and tylosin. Only to be incorporated by a manufacturer who is approved to mix at a rate of below 2kg per tonne of final feed. Studies have shown that at tiamulin hydrogen fumarate inclusion levels of 30-40g per tonne (equivalent to 1.5-2.0mg/kg bodyweight daily) no interation occurs with salinomycin at 60g per tonne of feed or monensin at 100g per tonne of feed.

Disposal

Dispose of any unused product and empty containers in accordance with guidance from your local waste regulation authority.

Marketing authorisation number

Vm 12501/4068

Marketing authorisation holder

Novartis Animal Health UK Ltd

Marketed and distributed by

Novartis Animal Health UK Ltd Frimley Business Park Frimley Camberley Surrey GU16 7SR

Tel: 01276 694402

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DHA Gold®

new

Presentation

DHA GOLD® is a dried, whole cell algae product derived from the microorganism Schizochytrium sp. that contains a minimum 18% DHA by weight. DHA GOLD® is a safe and consistent, vegetarian source of the omega-3 fatty acid docosahexaenoic acid (DHA).

Docosahexaenoic acid (DHA)

minimum 18%

Fat content

minimum 35%

Solids

minimum 94%

Appearance

Free flowing, golden brown flakes

Aroma

Slight marine to malt-like

Solubility in water

Insoluble

Density

30lb/ft3

Nutritional Composition

Moisture Protein Fibre Ash Fat Carbohydrates

Typical Fatty Acid Profile 14:0-Myristic acid 8.5% 16:0-Palmitic 23.2% 18:3n6-Linolenic 0.4% 20:4n6-Arachidonic 0.8% 20:5n3-EPA 1.9% 22:5n6-DPA 17.7% 22:6n3-DHA 42.3% Others 5.2%

Use

DHA omega-3 enrichment of animal proteins such as eggs, meat, milk and supplementation of diets of breeding animals.

Early nutrition and development.

DHA GOLD provides consistent levels of DHA that offers many advantages over other sources of omega-3s.

• All-natural, vegetarian source of DHA omega-3

• No fish or fish by-products

• Will not compromise taste, texture or aroma

• Non-GMO

• Sustainable supply

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2.0% 16.7% 4.5% 8.8% 55.6% 12.4%

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Precautions

Due to the high concentration of polyunsaturated fatty acids, the product is sensitive to air, heat, light and humidity. The product should be stored in dry, well-ventilated warehouse conditions in its original package. It is recommended that storage temperature not exceed 25°C (77°F).

Storage

A shelf life of 24 months as from date of manufacture can be achieved if the product is stored in original sealed packages.

Package sizes

15kg bags (50 bags per pallet)

Supplier

Novus Europe SA/NV Avenue Marcel Thiry 200 1200 Brussels Belgium

Telephone: Fax: Email: Website:

UK Contact

Dr Helen Stebbens Quarry Cottage Easton Wells Somerset BA5 1EE

+32 2 778 1411 +32 2 771 8287 info.europe@novusint.com www.novusint.com

Tel/Fax: Email:

®DHA GOLD is a registered trademark of Martek Biosciences Corporation

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+44 1749 870862 helen.stebbens@novusint.com

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digestarom®

Flavour and digestibility enhancer

1301 Milk Replacer, Premium, HC

Presentation

Beige to brown, free-flowing powder with a characteristic smell of vanilla and herbs.

Use

digestarom® 1301 is a mixture of essential oils, herbs, spices, extracts, nature-identical flavours, authorised additives, solvent and/or carrier to be added to milk replacers for calves and piglets.

The raw materials used in this product provide the milk replacer with a fine vanilla-like flavour, such as the farmers expect. The premium qualities of digestarom include tanning agents known for their positive influence on problems with diarrhoea.

Active ingredients

Davana (Davana), Hamamelis virginiana L. (Witch hazel), Juglans regia L. (Walnut), Quercus cortex (Oak), Vanille planifolia (Vanilla).

Dosage/administration

500g/tonne to be homogeneously mixed in the milk replacer.

Precautions

Avoid direct exposure to sunlight. Store in a dark and cool place. The boxes should be tightly secured. The product should be stored at warehouse temperature 5-20°C. Shelf life: 12 months.

Palatability

Extreme dosages, above the recommended amount, may cause feed intake problems.

Compatibility

Compatible with other feed additives such as probiotics, enzymes and acids.

Package sizes

250kg box pack of 10 x 25kg poly bags 25kg boxes with inner poly bag

Delivery

Item stocked and available for shipment within 24 hours of the order.

However, availability is subject to prior sale and out of stock items will be shipped within 14 days of the order, subject to market conditions.

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Further information

Safety data Flash point: not achievable Bulk density: 730-760kg/m3 Quality control 1. Sensory analysis: Triangular test using a 3% sugar solution. (standard of analysis available upon request). 2. Analysis by instrument: Chemical-physical data (reference value) and parameter for GC and GC-MS analysis available upon request.

EU authorisation

The product is in accordance with Regulation (EC) No 1831/2003 of the European Parliament and of the Council.

â&#x2014;&#x160; Supplier

MICRO-PLUS (GB) Ltd 37 Blomfield Street Bury St Edmunds IP33 1TD United Kingdom

Telephone: +44 1284 755650 Email: info@micro-plus.de Website: www.micro-plus.com

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digestarom®

Flavour and digestibility enhancer

1307 Finishing Pigs

Presentation

Olive, free-flowing powder with a characteristic smell of herbs.

Use

digestarom® 1307 is a mixture of essential oils, herbs, spices, extracts, flavour extracts and nature-identical flavours, authorised additives, solvent and/or carrier to be added to feedstuffs for finishing pigs.

The herbs and spices used in this product are selected with respect to their positive effects on digestion and to improve the palatability of the diet.

Active ingredients

Allium sativum L. (Garlic), Carum carvi L. (Cumin), Gentiana lutea (Gentian), Melissa officinalis L. (Melissa balm), Trigonella foenum graecum L. (Fenugreek).

Dosage/administration

The recommended dosage is 150g/tonne of complete feedstuff. This dose rate can be achieved by homogeneously mixing in premixes, mineral or finished feed.

Precautions

Avoid direct exposure to sunlight. Store in a dark and cool place. The boxes should be tightly secured. The product should be stored at warehouse temperature 5-20°C. Shelf life: 12 months.

Palatability

Extreme dosages, above the recommended amount, may cause feed intake problems.

Compatibility

Compatible with other feed additives such as probiotics, enzymes and acids.

Package sizes

250kg box pack of 10 x 25kg poly bags 25kg boxes with inner poly bag

Delivery

Item stocked and available for shipment within 24 hours of the order.

However, availability is subject to prior sale and out of stock items will be shipped within 14 days of the order, subject to market conditions.

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Further information

The product is stable up to 85°C for 25-30 seconds under normal pelleting conditions.

Safety data Flash point: not achievable Bulk density: 625-675kg/m3

Quality control 1. Sensory analysis: Triangular test using a 0.2% salt (NaCl) solution (standard of analysis available upon request). 2. Analysis by instrument: Chemical-physical data (reference value) and parameter for GC and GC-MS analysis available upon request.

EU authorisation

The product is in accordance with Regulation (EC) No 1831/2003 of the European Parliament and of the Council.

â&#x2014;&#x160; Supplier

MICRO-PLUS (GB) Ltd 37 Blomfield Street Bury St Edmunds IP33 1TD United Kingdom

Telephone: +44 1284 755650 Email: info@micro-plus.de Website: www.micro-plus.com

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digestarom®

Flavour and digestibility enhancer

1310 Sows

Presentation

Olive, free-flowing powder with a characteristic smell of herbs.

Use

digestarom® 1310 is a mixture of essential oils, herbs, spices, extracts, authorised additives, solvent and/or carrier to be added to feedstuffs for sows.

The herbs and spices used in this product are selected with respect to their positive effects on digestion and to improve the palatability of the diet.

Active ingredients

Allium cepa L. (Onion), Allium sativum L. (Garlic), Cinnamomum aromaticum Nees (Cinnamon), Davana (Davana), Foeniculum vulgarae var. Dulce Mil. (Fennel), Mentha arvensis L. (Peppermint), Pimpinella anisum L. (Anise).

Dosage/administration

The recommended dosage is 150g/tonne of complete feedstuff. This dose rate can be achieved by homogeneously mixing in premixes, mineral or finished feed.

Precautions

Avoid direct exposure to sunlight. Store in a dark and cool place. The boxes should be tightly secured. The product should be stored at warehouse temperature 5-20°C. Shelf life: 12 months.

Palatability

Extreme dosages, above the recommended amount, may cause feed intake problems.

Compatibility

Compatible with other feed additives such as probiotics, enzymes and acids.

Package sizes

250kg box pack of 10 x 25kg poly bags 25kg boxes with inner poly bag

Delivery

Item stocked and available for shipment within 24 hours of the order.

However, availability is subject to prior sale and out of stock items will be shipped within 14 days of the order, subject to market conditions.

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Further information

The product is stable up to 85°C for 25-30 seconds under normal pelleting conditions.

Safety data Flash point: not achievable Bulk density: 520-550kg/m3

Quality control 1. Sensory analysis: Triangular test using a 0.2% salt (NaCl) solution (standard of analysis available upon request). 2. Analysis by instrument: Chemical-physical data (reference value) and parameter for GC and GC-MS analysis available upon request.

EU authorisation

The product is in accordance with Regulation (EC) No 1831/2003 of the European Parliament and of the Council.

â&#x2014;&#x160; Supplier

MICRO-PLUS (GB) Ltd 37 Blomfield Street Bury St Edmunds IP33 1TD United Kingdom

Telephone: +44 1284 755650 Email: info@micro-plus.de Website: www.micro-plus.com

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digestarom®

Flavour and digestibility enhancer

1313 Calves/Lambs, Premium – Plus

Presentation

Olive, free-flowing powder with a characteristic smell of vanilla and herbs.

Use

digestarom® 1313 is a mixture of essential oils, herbs, spices, extracts, nature-identical flavours, authorised additives, solvent and/or carrier to be added to feedstuffs for calves and lambs.

The herbs and spices used in this product are selected with respect to their positive effects on digestion and to improve the palatability of the diet. The premium qualities of digestarom include tanning agents known for their positive influence on problems with diarrhoea.

Active ingredients

Angelica officinalis (Angelica), Glycyrrhiza glabra L. (Liquorice), Majorana hortensis Moench (Marjoram), Pimpinella anisum L. (Anise), Syzygium aromaticum L. (Clove).

Dosage/administration

The recommended dosage is 300g/tonne of complete feedstuff (equivalent to 0.25g/kg dry matter intake/animal/ day). This dose rate can be achieved by homogeneously mixing in premixes, mineral or finished feed.

Precautions

Avoid direct exposure to sunlight. Store in a dark and cool place. The boxes should be tightly secured. The product should be stored at warehouse temperature 5-20°C. Shelf life: 12 months.

Palatability

Extreme dosages, above the recommended amount, may cause feed intake problems.

Compatibility

Compatible with other feed additives such as probiotics, enzymes and acids.

Package sizes

250kg box pack of 10 x 25kg poly bags 25kg boxes with inner poly bag

Delivery

Item stocked and available for shipment within 24 hours of the order.

However, availability is subject to prior sale and out of stock items will be shipped within 14 days of the order, subject to market conditions.

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Further information

The product is stable up to 85°C for 25-30 seconds under normal pelleting conditions.

Safety data Flash point: not achievable Bulk density: 450-500kg/m3

Quality control 1. Sensory analysis: Triangular test using a 3% sugar solution (standard of analysis available upon request). 2. Analysis by instrument: Chemical-physical data (reference value) and parameter for GC and GC-MS analysis available upon request.

EU authorisation

The product is in accordance with Regulation (EC) No 1831/2003 of the European Parliament and of the Council.

â&#x2014;&#x160; Supplier

MICRO-PLUS (GB) Ltd 37 Blomfield Street Bury St Edmunds IP33 1TD United Kingdom

Telephone: +44 1284 755650 Email: info@micro-plus.de Website: www.micro-plus.com

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digestarom®

Flavour and digestibility enhancer

1317 Poultry, Premium

Presentation

Beige to light brown, free-flowing powder with a characteristic smell of herbs.

Use

digestarom® 1317 is a mixture of essential oils, herbs, spices, extracts, authorised additives, solvent and/or carrier to be added to feedstuffs for broilers, turkeys, laying hens and ducks.

The herbs and spices used in this product are selected with respect to their positive effects on digestion and to improve the palatability of the diet. The premium qualities of digestarom include tanning agents known for their positive influence on problems with diarrhoea.

Active ingredients

Foeniculum vulgarae var. Dulce Mil. (Fennel), Melissa officinalis L. (Melissa balm), Mentha arvensis L. (Peppermint), Pimpinella anisum L. (Anise), Quercus cortex (Oak), Syzygium aromaticum L. (Clove), Thymus vulgaris L. (Thyme).

Dosage/administration

The recommended dosage is 150g/tonne of complete feedstuff. This dose rate can be achieved by homogeneously mixing in premixes, mineral or finished feed.

Precautions

Avoid direct exposure to sunlight. Store in a dark and cool place. The boxes should be tightly secured. The product should be stored at warehouse temperature 5-20°C. Shelf life: 12 months.

Palatability

Extreme dosages, above the recommended amount, may cause feed intake problems.

Compatibility

Compatible with other feed additives such as probiotics, enzymes and acids.

Package sizes

250kg box pack of 10 x 25kg poly bags 25kg boxes with inner poly bag

Delivery

Item stocked and available for shipment within 24 hours of the order.

However, availability is subject to prior sale and out of stock items will be shipped within 14 days of the order, subject to market conditions.

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Further information

The product is stable up to 85°C for 25-30 seconds under normal pelleting conditions.

Safety data Flash point: not achievable Bulk density: 845-890kg/m3

Quality control 1. Sensory analysis: Triangular test using a 0.2% salt (NaCl) solution (standard of analysis available upon request). 2. Analysis by instrument: Chemical-physical data (reference value) and parameter for GC and GC-MS analysis available upon request.

EU authorisation

The product is in accordance with Regulation (EC) No 1831/2003 of the European Parliament and of the Council.

â&#x2014;&#x160; Supplier

MICRO-PLUS (GB) Ltd 37 Blomfield Street Bury St Edmunds IP33 1TD United Kingdom

Telephone: +44 1284 755650 Email: info@micro-plus.de Website: www.micro-plus.com

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digestarom®

Flavour and digestibility enhancer

1319 Dairy Cattle, MLF

Presentation

Beige to light brown, free-flowing powder with a characteristic smell of herbs.

Use

digestarom® 1319 is a mixture of essential oils, herbs, spices, extracts, flavour extracts, natural and nature-identical flavours, authorised additives, solvent and/or carrier to be added to feedstuffs for dairy cows.

The herbs and spices used in this product are selected with respect to their positive effects on digestion and to improve the palatability of the diet.

Active ingredients

Allium cepa L. (Onion), Allium sativum L. (Garlic), Calendula officinalis L. (Marigold), Mentha arvensis L. (Peppermint).

Dosage/administration

The recommended dosage is 2-3g per animal per day. This dose can be achieved by homogeneously mixing in premixes, mineral or finished feed.

Precautions

Avoid direct exposure to sunlight. Store in a dark and cool place. The boxes should be tightly secured. The product should be stored at warehouse temperature 5-20°C. Shelf life: 12 months.

Palatability

Extreme dosages, above the recommended amount, may cause feed intake problems.

Compatibility

Compatible with other feed additives such as probiotics, enzymes and acids.

Package sizes

250kg box pack of 10 x 25kg poly bags 25kg boxes with inner poly bag

Delivery

Item stocked and available for shipment within 24 hours of the order.

However, availability is subject to prior sale and out of stock items will be shipped within 14 days of the order, subject to market conditions.

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Further information

The product is stable up to 85°C for 25-30 seconds under normal pelleting conditions.

Safety data Flash point: not achievable Bulk density: 820-845kg/m3

Quality control 1. Sensory analysis: Triangular test using a 0.2% salt (NaCl) solution (standard of analysis available upon request). 2. Analysis by instrument: Chemical-physical data (reference value) and parameter for GC and GC-MS analysis available upon request.

EU authorisation

The product is in accordance with Regulation (EC) No 1831/2003 of the European Parliament and of the Council.

â&#x2014;&#x160; Supplier

MICRO-PLUS (GB) Ltd 37 Blomfield Street Bury St Edmunds IP33 1TD United Kingdom

Telephone: +44 1284 755650 Email: info@micro-plus.de Website: www.micro-plus.com

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digestarom® Flavour and digestibility enhancer

new

1324 Piglet, Premium – SQ

Presentation

Beige to light brown, free-flowing powder with a characteristic smell of herbs.

Use

digestarom® 1324 is a mixture of essential oils, herbs, spices, extracts, flavour extracts, natural and nature-identical flavours, saccharin sodium (E954 iii) (300g/kg), neohesperidindihydrochalon (NHDC, E959), authorised additives, solvent and/ or carrier to be added to feedstuffs for piglets.

NB: This product contains saccharin sodium which, according to EU feedstuff regulations, can only be used for piglets up to 4 months of age.

The herbs and spices used in this product are selected with respect to their positive effects on digestion and to improve the palatability of the diet. The premium qualities of digestarom include tanning agents known for their positive influence on problems with diarrhoea.

Active ingredients

Foeniculum vulgarae var. Dulce Mil. (Fennel), Melissa officinalis L. (Melissa balm), Mentha arvensis L. (Peppermint), Pimpinella anisum L. (Anise), Quercus cortex (Oak), Syzygium aromaticum L. (Clove), Thymus vulgaris L. (Thyme).

Dosage/administration

The recommended dosage is 300g/tonne of complete feedstuff. This dose rate can be achieved by homogeneously mixing in premixes, mineral or finished feed.

The inclusion of saccharin sodium is in accordance with feedstuff regulations in the EU at the highest possible amount of 150g/ tonne of finished feed.

Precautions

Avoid direct exposure to sunlight. Store in a dark and cool place. The boxes should be tightly secured. The product should be stored at warehouse temperature not above 25°C. Shelf life: 12 months.

Palatability

Extreme dosages, above the recommended amount, may cause feed intake problems.

Compatibility

Compatible with other feed additives such as probiotics, enzymes and acids.

Package sizes

250kg box pack of 10 x 25kg poly bags 25kg boxes with inner poly bag

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Delivery

Item stocked and available for shipment within 24 hours of the order.

However, availability is subject to prior sale and out of stock items will be shipped within 14 days of the order, subject to market conditions.

Further information

The product is stable up to 85째C for 25-30 seconds under normal pelleting conditions.

All ingredients are listed by GRAS.

Quality control 1. Sensory analysis: Triangular test using water solution (standard of analysis available upon request). 2. Analysis by instrument: Chemical-physical data (reference value) and parameter for GC and GC-MS analysis available upon request.

EU authorisation

The product is in accordance with Regulation (EC) No 1831/2003 of the European Parliament and of the Council.

Supplier

MICRO-PLUS (GB) Ltd 37 Blomfield Street Bury St Edmunds IP33 1TD United Kingdom

Telephone: +44 1284 755650 Email: info@micro-plus.de Website: www.micro-plus.com

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Ecomectin速 6mg/g Premix for MFS for Pigs new Presentation

Ecomectin速 6 mg/g Premix for Medicated Feeding Stuff for Pigs is a yellow-brown free-flowing granular premix. It contains 0.6% w/w ivermectin.

Uses

Treatment of nematode or arthropod infections due to:

Gastrointestinal roundworms Ascaris suum (adults and L4) Hyostrongylus rubidus (adults and L4) Oesophagostomum spp. (adults and L4) Strongyloides ransomi (adults)*

Lungworms Metastrongylus spp. (adults)

Lice Haematopinus suis

Mange mites Sarcoptes scabiei var. suis

*Given to pregnant sows before farrowing, it effectively controls transmission via milk of S. ransomi to piglets.

Dosage/administration

To ensure thorough dispersion of the product it should first be mixed with a suitable quantity of feed ingredients before incorporation in the final mix.

The recommended dose level is 0.1mg ivermectin/kg bodyweight fed daily for seven consecutive days.

The appropriate inclusion rate of the ivermectin premix, in grams per tonne of finished feed, can be calculated as follows: Premix inclusion rate (g/tonne feed) = 100 x average bodyweight (kg) 6 x average daily feed intake (kg) In order to avoid under or overdosing, pigs to be treated should be grouped by weight and the dose to be administered should be calculated based on the heaviest animal in the group.

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Growing pigs: The recommended dose level of 0.1mg/kg bodyweight daily for seven days is obtained under most circumstances, for pigs up to 40kg bodyweight, by including 333g ivermectin premix in each tonne of final feed. The ivermectin premix should be thoroughly mixed in the finished feed and fed continuously as the only ration for seven consecutive days. In pigs weighing 40kg liveweight and over, average daily feed consumption may fall below a feed intake of 5% of bodyweight where restricted feeding programmes are in use or where pigs are fed a ration high in protein. For pigs weighing 40kg and over, include 400g ivermectin premix in each tonne of final feed. Adult pigs: The recommended dose level for adult pigs weighing over 100kg liveweight is achieved under most circumstances by thoroughly mixing 1.67kg of the ivermectin premix in each tonne of swine ration. The resultant medicated feed is to be fed at the rate of 1kg per 100kg of bodyweight each day for seven consecutive days, as part of the individual ration. Where medicated feed is to be fed as part of the ration, it is recommended that the ivermectin medicated feed is fed first. After this is consumed, any remainder of the daily feed allocation should be provided. This should be repeated for seven consecutive days. Alternatively, where dry feed intake can be accurately determined and all animals to be treated have similar bodyweight, the inclusion rate can be calculated using the previous formula to allow sole feeding of medicated feed. RECOMMENDED TREATMENT PROGRAMMES Growing pigs: Groups of growing pigs should be treated for seven consecutive days on transfer to clean quarters. Where an all-in all-out system is not possible, it is recommended that the in-feed parasite control programme should begin with treatment of all growing pigs already in the house. Breeding animals: Breeding animals are treated by feeding medicated feed for seven consecutive days. At the time of initiating any parasite control programme, it is important to treat all animals in the herd. After the initial treatment, use the premix regularly as follows: Sows: Treat 14-21 days prior to farrowing to minimise infection of piglets.

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Gilts: Treat 14-21 days prior to breeding. Treat 14-21 days prior to farrowing. Boars: Treat at least 2 times per year. Frequency of, and need for, treatments are dependent upon parasite exposure. This product should be incorporated by licensed feed manufacturers only. The product can be incorporated in pelleted feed preconditioned with steam for up to 10 seconds at a temperature not exceeding 65째C. Contra-indications, warnings, etc.

Contra-indications None.

Withdrawal Period Pigs: Twelve days.

The product can be administered to sows at any stage of pregnancy or lactation.

This product can be used in breeding animals.

Operator Warnings Mixing of the product with feed must take place in a well ventilated area. Use a dust mask and wear protective gloves and approved safety glasses. Avoid contact with skin and eyes. In case of accidental contact, wash the affected area thoroughly with clean running water. If eye irritation persists, seek medical advice. Wash exposed skin after use. Do not smoke, eat or drink during use.

General Precautions For animal treatment only.

Extremely dangerous to fish and aquatic life. Do not contaminate surface waters or ditches with the product or used container.

Further Information In the absence of compatibility studies, this veterinary medicinal product must not be mixed with other products.

When included in the ration of pigs at levels up to 5 times the recommended dose of 0.1mg ivermectin per kg bodyweight for 21 consecutive days (3 times the recommended treatment period), the product did not produce treatment related adverse reactions. No antidote has been identified.

Exposure of treated pigs to infected animals, contaminated premises, soil or pasture may result in reinfestation and retreatment may be necessary. Since the effect of ivermectin on

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mange mites is not immediate, avoid direct contact between treated and untreated pigs for at least one week after completion of treatment. Because louse eggs are unaffected by ivermectin and may take up to three weeks to hatch, re-treatment may be necessary.

Anthelmintic use that might lead to an increased risk of development of resistance to anthelmintic drugs includes:

(i) Too frequent and repeated use of anthelmintics from the same class over an extended period of time, and

(ii) Underdosing

Veterinary advice should be given on appropriate dosing programs and stock management to achieve adequate parasite control and reduce the likelihood of anthelmintic resistance developing.

Pharmaceutical precautions

Do not store above 25째C.

Store in a dry place.

Shelf-life of the veterinary medicinal product as packaged for sale: 18 months.

Shelf-life after incorporation into feed: 8 weeks in meal and 4 weeks in pellets.

Legal category

POM-VPS

Package quantities

333g foil sachets.

5kg foil bag inside a polypropylene/paper laminate bag.

Marketing authorisation number:

Vm 13277/4020

Marketing authorisation holder:

ECO Animal Health Ltd 78 Coombe Road New Malden Surrey KT3 4QS

Keep out of reach and sight of children.

Tel: Fax: E-mail: Web:

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020 8447 8899 020 8447 9292 enquiries@ecoanimalhealth.com www.ecoanimalhealth.com

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Econase® Wheat Plus

new

Presentation

ECONASE® Wheat Plus is a preparation of endo 1.4 β-xylanase and endo 1.3 (4) - β-glucanase. Both are produced by Trichoderma reesei and standardised to minimum enzyme activities. Supplied as powder or liquid product.

Use

In animal diets containing non-starch polysaccharides (NSP). Specifically formulated to improve the nutritional value of diets containing viscous cereals such as wheat, barley, rye, oats or triticale for monogastric animals.

Dosage/administration

Recommended dose rates for broiler and turkey diets including wheat, barley, rye or triticale:

Broilers Turkeys

Powder 20g/tonne 20g/tonne

Liquid 130g/tonne 130g/tonne

Package sizes

Econase® Wheat P Plus: 20kg Econase® Wheat L Plus: 120kg and 1000kg

Further information

Guaranteed minimum activity 800,000 BXU/g (β-xylanase) and 200,000 BU/g (β-glucanase) Econase® Wheat P Plus (powder).

120,000 BXU/g (β-xylanase) and 30,000 BU/g (β-glucanase) Econase® Wheat L Plus (liquid).

Stability and storage Econase® Wheat P Plus: 12 months when stored at 23°C Econase® Wheat L Plus: 12 months when stored at 10°C

Thermostability It is recommended to use Econase® Wheat L Plus when the conditioning and pelleting temperature exceeds 75°C.

EU authorisation

No 63

Supplier

AB Vista™ 3 Woodstock Court Blenheim Road Marlborough Business Park Marlborough Wiltshire SN8 4AN United Kingdom

Telephone: Fax: Email: Website:

+44 (0)1672 517650 +44 (0)1672 517660 info@ab-vista.com www.ab-vista.com

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Econase® XT 25

new

Presentation

Econase® XT 25 is an enzyme preparation produced by Trichoderma reesei. Its main activity is a thermostable endo 1,4 ß-xylanase. Supplied as powder (XT 25 P) or liquid (XT 25 L) product.

Use

Econase® XT 25 is recommended for use in animal feeds based on wheat, maize, triticale or rye.

Dosage/administration

Recommended dose rates for broiler, turkey and piglet diets including wheat, barley, rye or triticale:

Broilers: Turkeys: Piglets:

Package sizes

Econase® XT P (powder): 25kg Econase® XT L (liquid): 120kg and 1000kg

Further information

Guaranteed minimum activity 160,000 BXU/g (β-xylanase) in Econase® XT 25 P 160,000 BXU/g (β-xylanase) in Econase® XT 25 L

Stability and storage Econase® XT 25 P: 12 months when stored at 23°C Econase® XT 25 L: 12 months when stored at 10°C

Thermostability Econase® XT 25 P can be used in diets with conditioning and pelleting temperatures of up to 95°C.

EU authorisation

tba

Supplier

AB Vista™ 3 Woodstock Court Blenheim Road Marlborough Business Park Marlborough Wiltshire SN8 4AN United Kingdom

Telephone: Fax: Email: Website:

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100g/tonne of powder or liquid product 100g/tonne of powder or liquid product 150g/tonne of powder or liquid product

+44 (0)1672 517650 +44 (0)1672 517660 info@ab-vista.com www.ab-vista.com

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ECONOR 10% Premix Presentation

Econor 10% Premix contains valnemulin in the form of valnemulin hydrochloride. Valnemulin hydrochloride equivalent to

106.5mg/g 100mg/g valnemulin base

Uses

For the treatment and prevention of swine dysentery.

For the treatment of clinical signs of porcine proliferative enteropathy (ileitis).

For the prevention of clinical signs of porcine colonic spirochaetosis (colitis) when the disease has been diagnosed in the herd. Treatment and prevention of swine enzootic pneumonia. At the recommended dosage of 10-12mg/kg bodyweight, lung lesions and weight loss are reduced, but infection with Mycoplasma hyopneumoniae is not eliminated.

Dosage/administration

Dose • Treatment of swine dysentery: The dosage is 3-4mg/kg bodyweight per day • Prevention of swine dysentery: The dosage is 1.0-1.5mg/kg bodyweight per day. • Treatment of clinical signs of porcine proliferative enteropathy (ileitis) The dosage is 3-4mg/kg bodyweight per day. • Prevention of clinical signs of porcine colonic spirochaetosis (colitis) The dosage is 1.0-1.5mg/kg bodyweight per day. • Treatment and prevention of swine enzootic pneumonia The dosage is 10-12mg/kg bodyweight per day. Method and route of administration For oral use. Treatment of swine dysentery The dosage is 3-4mg/kg bodyweight per day. This is normally achieved by incorporating Econor 10% Premix at a level of 750g/tonne feed to provide 75mg active substance per kg feed. The medicated feed should be fed as the sole ration daily for a minimum of seven days and up to four weeks or until signs of disease disappear. This dose level is effective

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in the treatment of clinical disease, but higher dosages or longer duration of treatment may be necessary for complete elimination of infection. It is important to institute medication as early as possible in an outbreak of swine dysentery. In pigs with reduced appetite or on restricted feed, inclusion levels may need to be increased to achieve target dosage. If there is no response to treatment within five days, the diagnosis should be re-established. Prevention of swine dysentery The dosage is 1.0-1.5mg/kg bodyweight per day. This is normally achieved by incorporating Econor 10% Premix with the final feed at a level of 250g/tonne feed to provide 25mg active substance per kg feed. The medicated feed should be fed as the sole ration daily for a minimum of seven days and up to four weeks or until signs of disease disappear. Long term preventative use of valnemulin should be avoided by improving management practice and thorough cleansing and disinfection. Consideration should be given to the eradication of infection from the farm. Treatment of clinical signs of porcine proliferative enteropathy (ileitis) The dosage is 3-4 mg/kg bodyweight per day. This is normally achieved by incorporating Econor 10% Premix at a level of 750 g/tonne feed to provide 75 mg active substance per kg feed. The medicated feed should be fed as the sole ration daily for two weeks or until signs of disease disappear. This dose level is effective under normal situations in the treatment of clinical signs of the disease, but higher dosages or longer duration of treatment may be necessary for complete elimination of infection. It is important to institute medication as early as possible in an outbreak of porcine proliferative enteropathy. If there is no response to treatment within five days, the diagnosis should be re-established. For severely affected animals which fail to respond to treatment within 3-5 days, parenteral treatment should be considered. Prevention of clinical signs of porcine colonic spirochaetosis (colitis) The dosage is 1.0-1.5 mg/kg bodyweight per day. This is normally achieved by incorporating Econor 10% Premix with the final feed at a level of 250 g/tonne feed to provide 25 mg active substance per kg feed. The medicated feed should be fed as the sole ration daily for four weeks. Long term preventative use of valnemulin should be avoided by improving management practice and thorough cleansing and disinfection. Consideration should be given to the eradication of infection from the farm.

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Treatment and prevention of swine enzootic pneumonia The dosage is 10-12mg/kg bodyweight per day. This is normally achieved, for example, in grower pigs, by incorporating Econor 10% Premix at a level of 2kg/tonne to provide 200mg active substance per kg feed depending on pigs’ feed intake. Mg Econor 10% Premix/kg feed = Dosage required (mg/kg) x 10 x bodyweight (kg) Daily feed intake (kg) The medicated feed should be fed as the sole ration daily for up to three weeks. In older pigs, or in pigs with reduced appetite or on restricted feed intake, inclusion levels may need to be increased to achieve target dosage. Secondary infection by organisms such as Pasteurella multocida and Actinobacillus pleuropneumoniae may complicate enzootic pneumonia and require specific medication. Mixing Instructions The product has been shown to be stable to the pelleting process at temperatures of 75°C. Aggressive pelleting conditions such as temperatures in excess of 80°C and the use of abrasive substances for pre-mixture should be avoided. To achieve good mixture and homogeneity of incorporation the use of a pre-mixture is recommended. The required quantity of product is thoroughly mixed with a feed ingredient of similar physical nature (e.g. wheat middlings) in the proportion: 1 part Econor 10% Premix to 10 parts feed ingredient. Contra-indications, undesirable effects, warnings, etc

For animal treatment only. Keep out of reach of children. Do not administer the product to pigs receiving ionophone antibiotics. Valnemulin has been shown to interact with the ionophore antibiotics such as monensin, salinomycin and narasin and may result in signs indistinguishable from an ionophore toxicosis. Animals should not receive products containing monensin, salinomycin or narasin, during or at least five days before or after treatment with valnemulin. Severe growth depression, ataxia, paralysis or death may result. Whilst studies in rats and mice have not produced any evidence of teratogenic effect, the safety in pregnant and lactating sows has not been established. Valnemulin should not be administered to rabbits because of its toxicity in this species. Medication of pigs with valnemulin has led to the occurrence of adverse reactions in the EU. Of the 36 cases reported in 1999 to 2000, the majority (34) occurred in Denmark and Sweden (one case each in Finland and Ireland). In these countries, the incidence ranged from 0.03 to 1.76% of all pigs treated. On affected farms, one third of the pigs were affected, with a mortality rate of 1%.

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Affected pigs are pyrexic, exhibit inappetence, and in severe cases become uncoordinated, ataxic and may become recumbent. A percentage of such pigs may also suffer oedema or erythema (posterior in distribution), and palpebral oedema. The reaction has been studied in controlled trials in susceptible animals. Mortality was less than 1%, but might be increased as a result of secondary infections. In the case of a adverse reaction, immediate withdrawal of medication is recommended. Severly affected pigs should be removed to clean dry pens and given symptomatic treatment, including treatment for concurrent disease. An epidemiological survey has indicated that there is likely to be an association between the susceptibility to adverse reactions and the Danish and Swedish Landrace breeds, and their crossbreeds thereof, especially in young pigs. Extreme care should therefore be taken in the use of Econor in pigs of Scandinavian origin. Valnemulin is well-accepted in feed, but administered at concentrations above 200ppm may result in transient reduction in food consumption associated with unpalatability during the first few days of feeding. When mixing the product and handling the final feed containing the product, direct contact with the skin and mucous membranes should be avoided. In case of accidental ingestion, seek medical advice immediately and show the product label. People with known hypersensitivity to valnemulin should administer the product with caution. Disposal of Unused Product Any unused product or waste material should be disposed of in accordance with local requirements. Withdrawal period 1 day. Pharmaceutical precautions

• Store below 25°C. • Store product in the original container. • Part-used containers should be tightly closed following dispensing. Shelf life: • 3 years for premix • 3 months, when incorporated into meal feed and protected from light and moisture. • 3 weeks, when incorporated into pelleted feed and protected from light and moisture.

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Legal category

POM-V

Package quantities

1kg and 25kg in aluminium-lined bag.

Further information

Valnemulin is an antibiotic belonging to the pleuromutilin group, which act by the inhibition of the initiation of protein synthesis at the level of the bacterial ribosome. For any information about this veterinary medicinal product, please contact the local representative of the Marketing Authorisation Holder.

Marketing authorisation numbers

1kg 25kg

EU/2/98/010/017 EU/2/98/010/018

Marketed and distributed by

Novartis Animal Health UK Ltd Frimley Business Park Frimley Camberley Surrey GU16 7SR

Tel: 01276 694402

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Elancoban速 G200 Presentation

A brown, free-flowing granular premix for incorporation into animal feedingstuffs containing 200g monensin activity per kg.

Uses

Broiler and layer replacement chickens: As an aid in the prevention of coccidiosis caused by Eimeria acervulina, E. brunetti, E. maxima, E. mivati, E. necatrix and E. tenella. Turkeys for fattening: As an aid in the prevention of coccidiosis caused by Eimeria adenoides, E. gallopavonis and E. meleagrimitis.

Dosage/administration

Mix the appropriate quantity of Elancoban G200 to obtain the recommended levels of monensin, with 20-50kg of a suitable feed component prior to incorporation into the bulk of the feed to be prepared. Incorporation only as described below: Broiler and layer replacement chickens: Elancoban G200 should be mixed thoroughly into layer replacement feeds at 0.5kg or a level up to 0.6kg per metric tonne. This will provide monensin equivalent to 100g or up to 120g monensin activity per tonne of completed feed. For broilers, inclusion of 0.5kg-0.625kg per metric tonne will provide monensin equivalent to 100g or up to 125g monensin activity per tonne of completed feed. Broiler chickens: Feed containing Elancoban G200 should be fed continuously as the only ration until three days before slaughter for human consumption. Layer replacement chickens: Feed containing Elancoban G200 should be fed continuously from day old up to a maximum of 16 weeks of age. Turkeys for fattening: It is recommended that 300-500g of Elancoban G200 be thoroughly mixed in one tonne of complete turkey feed. This will provide monensin equivalent to 60-100g activity per tonne of feed (60ppm-100ppm). Feed containing Elancoban G200 should be fed continuously as the only ration from day old up to three days before slaughter for human consumption, up to a maximum of 16 weeks of age.

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Contra-indications, warnings, etc.

For animal treatment only. Keep out of reach of children. Elancoban G200 should be carefully mixed with the mineral supplement or other feed ingredients prior to the feed being manufactured to ensure even distribution in the final feed. When mixing and handling Elancoban G200, use protective clothing, impervious gloves and a dust mask. Operators should wash thoroughly with soap and water after handling. If accidental eye contact occurs, immediately rinse thoroughly with water. Poultry must not be slaughtered for human consumption during treatment or for at least three days after the last treatment. For use in feeds for broiler and layer replacement chickens and turkeys for fattening only. Do not feed to guinea fowl or other avian species, or to chickens or turkeys producing eggs. For replacement chickens. Do not allow horses or other equines access to feeds containing Elancoban G200. Ingestion of monensin by horses has been fatal. The product must not be mixed or used simultaneously with another coccidiostat. Animals, including birds, should not be treated with products containing tiamulin while receiving, or for at least seven days before or after receiving feed containing Elancoban G200. Severe growth depression or death may result. Instances of possible intoxication have been reported in turkeys receiving chloramphenicol or sulphonamides while consuming feed supplemented with monensin.

Pharmaceutical precautions

Store in a cool, dry place. For shelf life see expiry date on label. The product can be incorporated into pelleted feed, pre-conditioned with steam, at a temperature of 118째C at a pressure of 34 bar.

Legal category

Specified feed additive (coccidiostat)

Package quantities

25kg in laminated paper/woven polyethylene sacks.

Further information

When used as recommended the product should only be incorporated by non-farm mixers.

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European authorisation number

757

Supplier

Elanco Animal Health Lilly House Priestley Road Basingstoke Hampshire RG24 9NL

Tel: Fax:

®Elancoban – registered trade mark for monensin, Eli Lilly and Company Ltd.

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(01256) 353131 (01256) 779510

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Enteroguard®

new

Presentation

Enteroguard® is an aromatic additive containing a combination of freeze-dried garlic and freeze-dried cinnamon oil on a carrier of calcium carbonate.

Product information Uses

Active Components Alliin (precursor for Allicin) from garlic Cinnamaldehyde (from cinnamon oil)

Dosage/administration

Piglets: Growing pigs: Broilers – starters: Broilers – finishers: Calves: Rabbits – starters: Rabbits – finishers: Turkeys < 10 weeks: Turkeys > 10 weeks:

Legal category

Category 2b (Annex I Reg 1831/2003)

Natural or corresponding synthetic chemically defined flavourings.

Natural products – botanically defined

Further information

Shelf life 2 years.

Package quantities

25kg drums.

Supplier

Orffa Additives BV Vierlinghstraat 51 4251 LC Werkendam The Netherlands

Orffa UK Office PO Box 113 Northallerton North Yorkshire DL6 1YH

Tel: +31 (0) 183 44 77 44 Fax: +31 (0) 183 44 30 60 E-mail: info@orffa.com Website: www.orffa.com

Tel: +44 (0) 1609 772881 Fax: +44 (0) 1609 780941

Enteroguard® can be used in diets for different animal species. Both garlic and cinnamon oil have been reported to inhibit a specific range of pathogenic bacteria, viruses, moulds and yeasts and may thereby stimulate gut health.

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500g/tonne 500g/tonne 500g/tonne 250g/tonne 1000g/tonne 500g/tonne 1000g/tonne 500g/tonne 250g/tonne

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Fibosel

new

Presentation

Appearance Free-flowing, light tan powder with a characteristic yeast odour.

General Fibosel contains inactive yeast cell wall fractions from a Saccharamyces cerevisiae strain rich in β-1,3/1,6-glucans.

Fibosel is produced by processing yeast cells in a highly controlled system. The yeast cell walls in Fibosel are purified to increase beta-glucan concentration and exposure. The product is rollerdried and packed in 25kg cardboard boxes.

This product is not a source of viable Saccharamyces cerevisiae cells. Fibosel is a feed ingredient to be used exclusively in animal feed.

Specification β-1,3/1,6-glucans Protein Moisture Ash

Uses

Fibosel contains beta-glucans which support the optimal functioning of the immune system of animal species and fish.

Dosage/administration

Poultry

100g/tonne of complete feed

Pigs

150g/tonne of complete feed

Calves

250-500g/tonne of complete feed

Marine Fish

500-1000g/tonne of complete feed

Freshwater Fish

500-1000g/tonne of complete feed

Crustaceans

500-1000g/tonne of complete feed

Further information

Storage Store in a cool, dry place in original packaging and protect from humidity. Keep product container tightly sealed when not in use.

EU authorisation

Fibosel is a yeast product that complies to Council Directive 82/471/EEC concerning products used in animal nutrition.

Package quantities

25kg cardboard box with PE in-liner.

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min. 30% min. 13% max. 8% max. 6%

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Supplier

Frank Wright Trouw Nutrition International Blenheim House Blenheim Road Ashbourne Derbyshire DE6 1HA Tel: Fax: Email: Website:

01335 341101 01335 341167 customer.services@frankwright.com www.frankwrighttrouw.com

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FINASE® Presentation

FINASE® is an enzyme preparation of 3-phytase produced by Trichoderma reesei and standardised to minimum phytase activity of 5000PPU/g. Supplied as powder or liquid product.

Use

Specifically developed for use in poultry and pig diets containing phytin-bound phosphorus.

Dosage/administration

Recommended dose for use in pig, sow, broiler, turkey and layer diets:

Pigs:

100g/tonne of powder or liquid product

Sows:

100g/tonne of powder or liquid product

Broilers:

100g/tonne of powder or liquid product

Turkeys:

100g/tonne of powder or liquid product

Layers:

60g/tonne of powder or liquid product

Package sizes

FINASE® P: 25kg FINASE® L: 25kg, 120kg and 1000kg

Further information

Guaranteed minimum activity 5,000 PPU/g in FINASE® P (powder). 5,000 PPU/g in FINASE® L (liquid).

Stability and storage FINASE® P: 12 months when stored at 23°C FINASE® L: 12 months when stored at 10°C

Thermostability It is recommended to use FINASE® L when the conditioning and pelleting temperature exceeds 75°C.

EU authorisation

E1632 and No 28

Supplier

AB Vista™ 3 Woodstock Court Blenheim Road Marlborough Business Park Marlborough Wiltshire SN8 4AN United Kingdom

Telephone: Fax: Email: Website:

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+44 (0)1672 517650 +44 (0)1672 517660 info@ab-vista.com www.ab-vista.com

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Flubenol® 5% w/w Oral Powder for Pigs

Presentation

White powder containing flubendazole 5% w/w (50mg/g) in a 600g tub.

◊ Uses

Flubendazole is a broad spectrum anthelmintic for oral administration, active against mature and immature stages of the following nematodes of the gastro-intestinal tract of the pig: Ascaris suum Hyostrongylus rubidus Oesophagostomum dentatum Trichuris suis Strongyloides ransomi

(large roundworm) (red stomach worm) (nodular worm) (whipworm) (threadworm)

Flubendazole is ovicidal. Dosage/administration

Individual treatment: (Single administration) Add 1g of Flubenol for each 10kg bodyweight on to the finished feed. (This is equivalent to 5mg of flubendazole per 1kg bodyweight). One 13g measuring spoon treats one 130kg sow. Treatment frequency Twice a year unless recommended otherwise by a veterinary surgeon. New arrivals should be treated on arrival and before mixing with other animals. Treatment of clinical worm infestations Consult a veterinary surgeon for initial identification of problem species. Treat relevant infestations at intervals shown below. Nodular worm: Large roundworm: Red stomach worm: Whipworm:

Contra-indications, warnings, etc.

every 2 months every 2 months every month every 6 weeks

Withdrawal periods Animals must not be slaughtered for human consumption during treatment. Pigs may be slaughtered for human consumption only after seven days from the last treatment. Warnings For animal treatment only. Keep out of reach of children.

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Accidental ingestion by humans should be avoided. Avoid direct skin contact. Wear overalls, safety glasses and impervious gloves when mixing and handling the product. Wash affected parts if skin contact occurs.If accidental eye contact occurs, immediately rinse thoroughly with water. If the operation involves potential exposure to dust, either a half mask respirator (European Standard EN149) with disposable filter or a non-disposable respirator (European Standard EN140) fitted with a filter (EN143) should be worn. Pharmaceutical precautions

Store in tightly closed original containers. Do not store above 25°C. The product will remain stable in finished feed for two months.The product can be incorporated into pelleted feed preconditioned with steam for up to 5 minutes at a temperature of 77°C and can withstand pelleting temperatures up to 116°C.

Legal category

POM-VPS

Package quantities

600g plastic tub with a 13g measuring spoon.

Further information

When incorporated into feed, for example, for treating small groups of animals, this product should only be incorporated by approved manufacturers.

Marketing authorisation number

Vm 00242/4055.

◊ Marketing authorisation holder

Janssen Animal Health A division of Janssen-Cilag Ltd 50-100 Holmers Farm Way High Wycombe Buckinghamshire HP12 4EG United Kingdom

Tel: Fax: E-mail:

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(01494) 567555 (01494) 567556 ahealth@jacgb.jnj.com

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Flubenol® 1.5% Medicated Premixture ◊

Presentation

1.5% (w/w) white, medicated premixture. Each 2kg bag contains 30g flubendazole.

Uses

Flubendazole is a broad spectrum anthelmintic for oral administration, active against mature and immature stages of the following nematodes of the gastro-intestinal and respiratory tract of the pig: Ascaris suum Hyostrongylus rubidus Oesophagostomum dentatum Metastrongylus apri Trichuris suis Strongyloides ransomi

(large roundworm) (red stomach worm) (nodular worm) (lungworm) (whipworm) (threadworm)

Flubendazole is ovicidal. Dosage/administration

Standard dosing regime Incorporation Add contents of one 2kg bag of Flubenol Medicated Premixture to at least 5kg of one of the feed ingredients and mix well. Thoroughly mix this premix with the remaining ingredients making in all one tonne of medicated feed, which can then be fed as mash or pellets. This gives 30mg flubendazole per kg of finished feed. Dosage Breeding stock should be treated for ten consecutive days. Weaners and finishing pigs should be treated for five consecutive days, or in the event of heavy Trichuris infestation, for ten consecutive days. Variable dosing regime For increased flexibility, the standard dosage can be divided and administered over differing periods of time, as shown below. Incorporation Add the required amount of Flubenol Medicated Premixture to at least 5kg of one of the feed ingredients and mix well. Thoroughly mix this premix with the remaining ingredients making in all one tonne of medicated feed, which can then be fed as mash or pellets.

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Dosage a) Breeding stock Amount of Flubenol Medicated Premixture to add to each 5kg premix for making up each tonne of final feed

Flubendazole inclusion rate in final feed (mg/kg)

Duration of treatment (days)

1333g

20

14

1000g

15

21

666g

10

28

Uses

Ascaris suum, Oesophagostomum dentatum and Hyostrongylus rubidus

b) Weaners and fattening pigs Amount of Flubenol Medicated Premixture to add to each 5kg premix for making up each tonne of final feed

Flubendazole inclusion rate in final feed (mg/kg)

Duration of treatment (days)

Uses

666g

10

14

500g

7.5

21

Ascaris suum, Oesophagostomum dentatum and Hyostrongylus rubidus

In the event of a heavy Trichuris infestation, use 2kg Flubenol Medicated Premixture per tonne (30mg/kg final feed) for ten days. Treatment frequency General herd treatment: twice a year unless recommended otherwise by a veterinary surgeon. Treat the whole herd at the same time to minimise the risk of re-infestation. Pigs brought on to the premises should be treated on arrival and before mixing with other animals. Treatment of clinical worm infestations Consult a veterinary surgeon for initial identification of worm species present. Treat relevant infestations at intervals shown below: Lungworm: Nodular worm: Large roundworm: Red stomach worm: Whipworm: Contra-indications, warnings, etc.

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every 3-4 weeks every 2 months every 2 months every month every 6 weeks

Warnings For animal treatment only. Keep out of reach of children.

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Withdrawal periods Animals must not be slaughtered for human consumption during treatment. Pigs may be slaughtered for human consumption only after seven days from the last treatment. Operator Warning Accidental ingestion by humans should be avoided. Avoid direct skin contact. Wear overalls, safety glasses and impervious gloves when mixing and handling the product. Wash affected parts if skin contact occurs.If accidental eye contact occurs, immediately rinse thoroughly with water. If the operation involves potential exposure to dust, either a half mask respirator (European Standard EN149) with disposable filter or a non-disposable respirator (European Standard EN140) fitted with a filter (EN143) should be worn. Disposal Dispose of empty containers in the farm refuse. Used containers should not be recycled.

Pharmaceutical precautions

Store in tightly closed original containers. Do not store above 25°C. Flubenol Medicated Premixture can be incorporated into pelleted feed preconditioned with steam for up to five minutes at a temperature of 77°C and can withstand pelleting temperatures up to 116°C.

The product will remain stable in finished feed for up to eight weeks.

◊ Legal category

POM-VPS

Package quantities

2kg bags

◊ Further information

This product should only be incorporated by approved manufacturers at the 2kg per tonne inclusion rate. This premixture is produced from Flubenol 5% Premix containing flubendazole 5% w/w with marketing authorisation number Vm 00242/4017.

◊ Supplier

Janssen Animal Health A division of Janssen-Cilag Ltd 50-100 Holmers Farm Way High Wycombe Buckinghamshire HP12 4EG United Kingdom

Tel: Fax: E-mail:

(01494) 567555 (01494) 567556 ahealth@jacgb.jnj.com

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Flubenol® 5% Premix for Medicated Feedingstuffs

Presentation

White medicated premix containing flubendazole 5% w/w (50mg/g) in a 25kg bag.

Uses

Flubendazole is a broad spectrum anthelmintic for oral administration, active against mature and immature stages of the following nematodes of the gastro-intestinal and respiratory tract of the pig: Ascaris suum Hyostrongylus rubidus Oesophagostomum dentatum Metastrongylus apri Trichuris suis Strongyloides ransomi

(large roundworm) (red stomach worm) (nodular worm) (lungworm) (whipworm) (threadworm)

Flubendazole is ovicidal. Dosage/administration

Standard dosing regime Incorporation Add 600g of Flubenol premix to at least 5kg of one of the feed ingredients and mix well. Thoroughly mix this premix with the remaining ingredients making in all one tonne of medicated feed, which can then be fed as mash or pellets. This gives 30mg flubendazole per kg of finished feed. Dosage Breeding stock should be treated for ten consecutive days. Weaners and fattening pigs should be treated for five consecutive days, or in the event of heavy Trichuris infestation, for ten consecutive days. Variable dosing regime For increased flexibility, the standard dosage can be divided and administered over differing periods of time, as shown below. Incorporation Add the required amount of Flubenol premix to at least 5kg of one of the feed ingredients and mix well. Thoroughly mix this premix with the remaining ingredients making in all one tonne of medicated feed, which can then be fed as mash or pellets.

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Dosage a) Breeding stock Amount of Flubenol 5% to add to each 5kg premix for making up each tonne of final feed

Flubendazole inclusion rate in final feed (mg/kg)

Duration of treatment (days)

400g

20

14

300g

15

21

200g

10

28

Uses

Ascaris suum, Oesophagostomum dentatum and Hyostrongylus rubidus

b) Weaners and fattening pigs Amount of Flubenol 5% to add to each 5kg premix for making up each tonne of final feed

Flubendazole inclusion rate in final feed (mg/kg)

Duration of treatment (days)

Uses

200g

10

14

150g

7.5

21

Ascaris suum, Oesophagostomum dentatum and Hyostrongylus rubidus

In the event of a heavy Trichuris infestation, use 600g/tonne (30mg/kg final feed) for ten days. Treatment frequency Twice a year unless recommended otherwise by the veterinary surgeon. Treat the whole herd at the same time to minimise the risk of re-infestation. New arrivals should be treated on arrival and before mixing with other animals. Treatment of clinical worm infestations Consult a veterinary surgeon for initial identification of problem species. Treat relevant infestations at intervals shown below: Lungworm: Large roundworm: Red stomach worm: Whipworm: Nodular worm: Contra-indications, warnings, etc.

Warnings For animal treatment only. Keep out of reach of children. Withdrawal periods Animals must not be slaughtered for human consumption during treatment. Pigs may be slaughtered for human consumption only after seven days from the last treatment.

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every 3-4 weeks every 2 months every month every 6 weeks every 2 months

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Operator Warning Accidental ingestion by humans should be avoided. Avoid direct skin contact. Wear overalls, safety glasses and impervious gloves when mixing and handling the product. Wash affected parts if skin contact occurs.If accidental eye contact occurs, immediately rinse thoroughly with water. If the operation involves potential exposure to dust, either a half mask respirator (European Standard EN149) with disposable filter or a non-disposable respirator (European Standard EN140) fitted with a filter (EN143) should be worn. Disposal Dispose of empty containers in the farm refuse. Used containers should not be recycled. Pharmaceutical precautions

Store in tightly closed original containers. Do not store above 25°C.The product will remain stable in finished feed for up to eight weeks. Flubenol 5% Premix can be incorporated into pelleted feed preconditioned with steam for up to five minutes at a temperature of 77°C and can withstand pelleting temperatures up to 116°C.

Legal category

POM-VPS

Package quantities

25kg bags

Further information

Flubenol 5% Premix may only be incorporated by approved manufacturers at the above incorporation rates.

Marketing authorisation number

Vm 00242/4017.

◊ Marketing authorisation holder

Janssen Animal Health A division of Janssen-Cilag Ltd 50-100 Holmers Farm Way High Wycombe Buckinghamshire HP12 4EG United Kingdom

Tel: Fax: E-mail:

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(01494) 567555 (01494) 567556 ahealth@jacgb.jnj.com

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Flubenvet® 2.5% Medicated Premixture ◊

Presentation

2.5% (w/w) white, medicated premixture containing 25mg/g flubendazole in 2.4kg bags and 240g tubs.

Uses

Flubendazole is a broad spectrum anthelmintic for oral administration, active against mature and immature stages of the following nematodes of the gastrointestinal and respiratory tract: Ascaridia galli Heterakis gallinarum Capillaria spp. Amidostomum anseris Trichostrongylus tenuis Syngamus trachea

(large roundworm) (caecal worm) (hair worm) (gizzard worm) (gapeworm)

Flubendazole has no adverse effect on egg laying and hatchability. Dosage/administration

2.4kg bags:

Incorporation Add required amount of Flubenvet Medicated Premixture to at least 5kg of one of the feed ingredients and mix well. Thoroughly mix this premix with the remaining ingredients making in all one tonne of medicated feed, which can be fed as pellets, mini-pellets, starter pellets or crumbs. Dosage (a) Pheasants and partridges – 2.4kg Flubenvet Medicated Premixture per tonne of feed. Dosage equivalent to 60g of flubendazole per tonne of feed (60mg/kg). Treat for seven consecutive days. (b) Chickens and Geese – 1.2kg Flubenvet Medicated Premixture per tonne of feed. Dosage equivalent to 30g flubendazole per tonne of feed (30mg/kg). Treat for seven consecutive days. (c) Turkeys – 800g Flubenvet Medicated Premixture per tonne of feed. Dosage equivalent to 20g flubendazole per tonne of feed (20mg/kg). Treat for seven consecutive days.

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240g tubs:

Incorporation Incorporate into the daily feed ration.

Dosage The 240g Flubenvet Medicated Premixture tub medicates 200kg of pelleted chicken or goose feed, 300kg of turkey feed or 100kg of pheasant feed. Treat for seven consecutive days. Treatment frequency On infected premises treatment at three weekly intervals may be necessary to control worm infestations.

Contra-indications, warnings, etc.

Warnings For animal treatment only. Keep out of the reach of children.

Withdrawal periods Birds must not be slaughtered for human consumption during treatment. Chickens, turkeys, geese, pheasants and partridges may be slaughtered for human consumption only from seven days after the end of treatment. Turkeys, geese, pheasants and partridges Eggs must not be presented for human consumption during treatment. Eggs may be presented for human consumption only after seven days from the end of treatment. Chickens Eggs may only be presented for human consumption during and after treatment when dosed at the rate of 30ppm in feed â&#x20AC;&#x201C; i.e. 1.2kg FlubenvetÂŽ Medicated Premixture per tonne of feed. Operator warnings Accidental ingestion by humans should be avoided. Avoid direct skin contact. Wear overalls, safety glasses and impervious gloves when mixing and handling the product. Wash affected parts if skin contact occurs. If accidental eye contact occurs, immediately rinse thoroughly with water. If the operation involves potential exposure to dust, either a half mask respirator (European Standard EN149) with disposable filter, or a non-disposable respirator (European Standard EN140) fitted with a filter (EN143) should be worn. Disposal Dispose of empty containers in the farm refuse. Used containers should not be recycled.

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Pharmaceutical precautions

Store in tightly closed original containers. Do not store above 25°C. Accurate mixing is essential. The product will remain stable in the finished feed for two months. The product can be incorporated into pelleted feed preconditioned with steam for up to five minutes at a temperature of 77°C and can withstand pelleting temperatures up to 116°C.

◊ Legal category

POM-VPS

Package quantities

2.4kg bags, 240g tubs.

Further information

The premixture is produced from Flubenvet containing flubendazole 5% w/w, with marketing authorisation number Vm 00242/4056. Flubenvet Medicated Premixture may only be incorporated by approved manufacturers at the above incorporation rates.

◊ Supplier

Janssen Animal Health A division of Janssen-Cilag Ltd 50-100 Holmers Farm Way High Wycombe Buckinghamshire HP12 4EG United Kingdom

Tel: Fax: E-mail:

(01494) 567555 (01494) 567556 ahealth@jacgb.jnj.com

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Flubenvet® 5% Premix for Medicated Feedingstuffs ◊

Presentation

White powder premix containing flubendazole 5% w/w (50mg/g) in a 12kg bag.

Uses

Flubendazole is a broad spectrum anthelmintic for oral administration, active against mature and immature stages and eggs of the following nematodes of the gastrointestinal and respiratory tract: Ascaridia galli Heterakis gallinarum Capillaria spp. Amidostomum anseris Trichostrongylus tenuis Syngamus trachea

(large roundworm) (caecal worm) (hair worm) (gizzard worm) (gapeworm)

Flubendazole has no adverse effect on egg laying and hatchability. Dosage/administration

Incorporation Add required amount of Flubenvet Premix to at least 5kg of one of the feed ingredients and mix well. Thoroughly mix this premix with the remaining ingredients making in all one tonne of medicated feed, which can be fed as pellets, mini-pellets, starter pellets or crumbs. Dosage (a) Pheasants and partridges – 1.2kg Flubenvet per tonne of feed. Dosage equivalent to 60g of flubendazole per tonne of feed (60mg/kg). Treat for seven consecutive days. (b) Chickens and Geese – 600g Flubenvet per tonne of feed. Dosage equivalent to 30g flubendazole per tonne of feed (30mg/kg). Treat for seven consecutive days. (c) Turkeys – 400g Flubenvet per tonne of feed. Dosage equivalent to 20g flubendazole per tonne of feed (20mg/kg). Treat for seven consecutive days. Treatment frequency On infected premises treatment at three weekly intervals may be necessary to control worm infestations.

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Contra-indications, warnings, etc.

Warnings For animal treatment only. Keep out of the reach of children.

Withdrawal periods Birds must not be slaughtered for human consumption during treatment. Chickens, turkeys, geese, pheasants and partridges may be slaughtered for human consumption only from seven days after the end of treatment. Turkeys, geese, pheasants and partridges Eggs must not be presented for human consumption during treatment. Eggs may be presented for human consumption only after seven days from the end of treatment. Chickens Eggs may only be presented for human consumption during and after treatment when dosed at the rate of 30ppm in feed – i.e. 600g Flubenvet per tonne of feed. Operator warnings Accidental ingestion by humans should be avoided. Avoid direct skin contact. Wear overalls, safety glasses and impervious gloves when mixing and handling the product. Wash affected parts if skin contact occurs. If accidental eye contact occurs, immediately rinse thoroughly with water. If the operation involves potential exposure to dust, either a half mask respirator (European Standard EN149) with disposable filter, or a non-disposable respirator (European Standard EN140) fitted with a filter (EN143) should be worn. Disposal Dispose of empty containers in the farm refuse. Used containers should not be recycled.

Pharmaceutical precautions

Store in tightly closed original containers. Do not store above 25°C. Accurate mixing is essential. The product will remain stable in the finished feed for two months. The product can be incorporated into pelleted feed preconditioned with steam for up to five minutes at a temperature of 77°C and can withstand pelleting temperatures up to 116°C.

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Legal category

POM-VPS

Package quantities

12kg bag.

Further information

Flubenvet may only be incorporated by approved manufacturers at the above incorporation rates.

Marketing authorisation number

Vm 00242/4056.

â&#x2014;&#x160; Marketing authorisation holder

Janssen Animal Health A division of Janssen-Cilag Ltd 50-100 Holmers Farm Way High Wycombe Buckinghamshire HP12 4EG United Kingdom

Tel: Fax: E-mail:

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(01494) 567555 (01494) 567556 ahealth@jacgb.jnj.com

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Keep this Handbook up-to-date! When this Handbook was published, in February 2009, everything possible had been done by the publisher and product suppliers to ensure the information contained was accurate and up-to-date. Inevitably, some products will be subject to important changes between publication of this edition and the next. Whenever we are notified of changes to product information contained in this edition, these changes will be posted on our website at: www.simonmounsey.com/hbupdate.htm The updates will be in the form of replacement pages which can be printed out and used to replace pages in the original. As an additional service to users of this book, you may register to receive notification whenever an updated page is posted. Simply send an email to mail@simonmounsey.com with the subject line â&#x20AC;&#x153;Handbook Updates 2009â&#x20AC;? and your email address for notification.

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FORMI® Presentation/use

FORMI® is the first EU-approved non-antibiotic performance enhancer for weaner and fattening pigs, as well as for sows. The advantages of FORMI® are: • increased growth performance • strong anti-microbial effect • excellent feed conversion FORMI® is the approved alternative to feed antibiotics for pigs. The approval was granted by the EU Commission on 2nd July 2001(No. 1334/2001; No. 676/2003). FORMI® fulfils tomorrow’s requirements today. • optimum safety for humans and the environment, • no residues • secure and easy handling

Dosage/administration

FORMI® is registered for piglets and growing/finishing pigs at an inclusion level of 6kg-18kg/tonne of feed and for sows at an inclusion level of 8kg-12kg/tonne of feed.

FORMI® is classified as a Specified Feed Additive under the Veterinary Medicines Regulations 2006 and does not require a veterinary prescription. Home-mixers with Royal Pharmaceutical Society of GB approval can use this product on farm.

Contra-indications, warnings, etc.

Can be used throughout the growing/finishing pig life cycle. No withdrawal period is required. Container should be tightly sealed and stored in a dry place. Wear gloves, mask and safety glasses when handling this product. In case of contact with skin, wash thoroughly with soap and water. In case of contact with eyes, immediately wash affected eyes for at least 15 minutes under running water. Do not mix or use simultaneously with feedingstuffs containing any other feed antibiotic or growth promoter described as such in the annexes to Directive 70/524.

Packing sizes

25kg and 1,000kg bags.

Legal category

Specified Feed Additive (non-antibiotic growth promoter) (under Veterinary Medicines Regulations 2006)

Zootechnical additive (growth promoter) (under 1831/2003)

◊ Supplier

ADDCON EUROPE GmbH Kaiserstraße 1a, D-53113 Bonn

Tel: Fax: Email: Website:

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+49 228 91910-0 +49 228 91910-60 info@addcon.net www.addcon.net

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Fylax® Presentation

Fylax® is a blend of organic acids, their salts and surfactants available either as Fylax® - DRY MP or Fylax® - LIQUID.

Composition Sorbic acid, Formic acid, Acetic acid, Lactic acid, Propionic acid, Ammonium propionate, L-ascorbic acid, Citric acid, Mono- and di-glycerides, and propandiol. Fylax® - DRY MP also contains silicon dioxide.

Physical properties

Fylax® - DRY MP

Colour:

White

Odour:

Acid

pH:

5.5-6.2

Bulk Density:

590g/litre

Flash Point:

None

Fylax® - LIQUID

Colour:

Light yellow

Odour:

Acid

pH:

5.5-6.2

Density at 20°C:

1.07kg/litre

Flash point (PMCC):

None

Solubility in water:

Good

Uses

Fylax® is a broad spectrum mould inhibitor that prevents the proliferation of a wide range of organisms in feed and raw materials.

Fylax® also binds free water, which prevents moisture migration that can occur with temperature variation. In this way Fylax® prevents the creation of zones of high moisture that are condusive to mould growth.

Dosage/administration

Compound Feed <14% moisture: 0.5-1.0kg/tonne

Compound Feed >14% moisture: seek advice

Contra-indications, warnings, etc.

For animal use only.

Safe handling recommendations are listed on the material safety data sheet.

No withdrawal period is required.

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Legal category

The components of Fylax速 - DRY MP and Fylax速 - LIQUID are fully approved by the EC as preservatives for use in animal feeds.

Package quantities

Fylax速 - DRY MP 25kg multiple layer paper bags with plastic liner.

Fylax速 - LIQUID 1000kg IBC, 25kg or 225kg drums.

Supplier

Frank Wright Trouw Nutrition International Blenheim House Blenheim Road Ashbourne Derbyshire DE6 1HA Tel: Fax: Email: Website:

01335 341101 01335 341167 customer.services@frankwright.com www.frankwrighttrouw.com

Manufacturer

Selko BV PO Box 4217 5004 JE Tilburg The Netherlands

Tel: Fax: Email: Website:

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0031 13 468 0333 0031 13 467 1698 info@selko.com www.selko.com

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Fysal® GB Presentation

Fysal® GB is a colourless mobile liquid blend of formic and propionic acid.

Composition Formic acid 68%, Propionic acid 20%, Water 12%.

Physical properties

Colour:

Colourless

Density at 20°C:

1.152kg/litre

Viscosity at 20°C:

1.8cSt

Flash point (PMCC):

61°C

Miscibility with water:

Complete

Crystallisation Point:

-21°C

Uses

Fysal® GB is a liquid organic acid antimicrobial treatment for compound feeds and raw materials. Application rates to eliminate Salmonella and other pathogens from raw materials will depend upon the type of raw material i.e. buffering capacity, level of contamination and post treatment storage period. Fysal® GB treatment of compound feed will control Salmonella and other pathogens, prevent recontamination of expanded/conditioned feed and provide effective mould inhibition.

Dosage/administration

Raw materials: 0.5%-2.0% w/w (dependant on type of material), sprayed into ribbon mixer/auger.

Compound feed (no heat treatment): 0.68% w/w.

Compound feed (heat treated): 0.50% w/w.

Contra-indications, warnings, etc.

For animal use only.

Safe handling recommendations are listed on the material safety data sheet.

Legal category

The components of Fysal® GB are fully approved by the EC as preservatives for use in animal feeds.

Package quantities

Bulk 10 and 20 tonne deliveries.

Containers 1000 litre IBC = 1152kg

No withdrawal period is required.

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Supplier

Frank Wright Trouw Nutrition International Blenheim House Blenheim Road Ashbourne Derbyshire DE6 1HA Tel: Fax: Email: Website:

01335 341101 01335 341167 customer.services@frankwright.com www.frankwrighttrouw.com

Manufacturer

Selko BV PO Box 4217 5004 JE Tilburg The Netherlands

Tel: Fax: Email: Website:

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0031 13 468 0333 0031 13 467 1698 info@selko.com www.selko.com

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GalliPro®

new

Presentation

GalliPro® is a gut flora stabiliser. The product is a powder, containing spores of Bacillus subtilis (DSM 17299) at a minimum of 1.6x109 colony forming units/gram.

The active ingredients will retain their activity after pelleting at 75-95°C. The Bacillus strain survives passage through the stomach and produces protease, amylase and lipase enzymes in the gastrointestinal tract, which increase the digestion of protein, starch and fat respectively. This leads to increased live weight gains, improved feed conversion ratios and reduced mortality.

Uses

Microbial feed additive for chickens for fattening during the entire growth cycle.

Dosage

Add 500-1000 grams per tonne of complete feed, equivalent to a concentration of 0.8-1.6 million spores per gram of feed.

Safety

As with all powders avoid inhalation of dust. A facemask, gloves and goggles should be worn when handling larger amounts of the product. In case of inhalation seek fresh air and avoid further contact. In case of skin or eye contact rinse with water. In case of oral intake drink plenty of water to dilute. The product is of no hazard according to the legislation on chemicals and hazardous substances.

Legal category

GalliPro® is approved under EU Registration Number 4b1821 as a microbial feed additive for chickens for fattening.

Storage

Store in a cool dry place at temperature not exceeding 37°C. The bag must be closed again after use.

Shelf life

When stored as specified above, up to 730 days (24 months).

Packaging

In 20kg net weight quantities in bags.

Supplier

Chr. Hansen (UK) Ltd. 2 Tealgate Charnham Park Hungerford Berkshire RG17 0YT

Tel: Fax: Contact:

01488 689800 01488 685436 Dr David Seale

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Genex Pig, Genex Poultry & Genex Turkey

Presentation

Genex pig, poultry and turkey are light brown, moist, granular powders. All exhibit a characteristic odour. Each product consists of a specific blend of volatile fatty acids, essential oils and plant extracts on an activated verxite base.

Uses

All the Genex products are naturally derived feed premixes designed to protect the nutritive value of feed, promote optimal digestibility and encourage maximum expression of genetic potential.

Dosage/administration

2kg per tonne in normal production situations 4kg per tonne in situations of high bacterial challenge

Contra-indications, warnings, etc.

For animal use only Keep out of reach of children No withdrawal period is required before slaughter Avoid contact with the skin as mild irritation may occur

Precautions

Store in a cool dry place. Shelf life of product is 12 months.

Legal category

Feed preservative

Packaging quantities

All Genex products are supplied in rip’n’tip pack sizes which include 2, 4, 6, 8, 10, 12, 16, 20 and 25kg bags.

◊ Supplier

Optivite Ltd Unit 5, Drayton Court Manton Wood Enterprise Park Worksop Nottinghamshire S80 2RS Tel: Fax: Email:

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01909 537380 01909 478919 info@optivite.com

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Glytrex™ Cu Presentation

new

Glytrex™ Cu is an organic form of the trace element copper. It is a blue powder containing:

• Minimum 15% by weight Copper (from Copper Chelate of Glycine Hydrate)

• Minimum 35.5% by weight Glycine

Use

Glytrex™ Cu should be fed continuously as a component of a complete diet at the following inclusion rates:

Cattle Broilers Turkeys Layers Ducks Swine Equine Goats

1.0g per head per day1,2 35-70g/tonne of complete feed1 35-70g/tonne of complete feed1 35-70g/tonne of complete feed1 35-70g/tonne of complete feed1 35-170g/tonne of complete feed1 1.0g per head per day1,2 0.06g per head per day1

1

2

Storage

A shelf life of 24 months as from date of manufacture can be achieved if the product is stored at ambient temperature in a sealed container and in dry conditions.

Package sizes

25kg bags

Supplier

Novus Europe SA/NV Avenue Marcel Thiry 200 1200 Brussels Belgium

Telephone: Fax: Email: Website:

UK Contact

Dr Helen Stebbens Quarry Cottage Easton Wells Somerset BA5 1EE

Or as directed by a qualified nutritionist Inclusion based on minimum Dry Matter intake of 10kg per day per animal

+32 2 778 1411 +32 2 771 8287 info.europe@novusint.com www.novusint.com

Tel/Fax: Email:

+44 1749 870862 helen.stebbens@novusint.com

™GLYTREX is a trademark of Novus International, Inc.

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Glytrex™ Fe Presentation

new

Glytrex™ Fe is an organic form of the trace element iron. It is a brown-green powder containing:

• Minimum 15% by weight Iron (from Ferrous Chelate of Glycine Hydrate)

• Minimum 43% by weight Glycine

Use

Glytrex™ Fe should be fed continuously as a component of a complete diet at the following inclusion rates:

Cattle Broilers Turkeys Layers Ducks Swine Equine Goats

1

Up to 2.0g per head per day1 65-130g/tonne of complete feed1 65-130g/tonne of complete feed1 65-130g/tonne of complete feed1 65-130g/tonne of complete feed1 65-350g/tonne of complete feed1 0.5g per head per day1 0.1g per head per day1

Or as directed by a qualified nutritionist

Storage

A shelf life of 24 months as from date of manufacture can be achieved if the product is stored at ambient temperature in a sealed container and in dry conditions.

Package sizes

25kg bags

Supplier

Novus Europe SA/NV Avenue Marcel Thiry 200 1200 Brussels Belgium

Telephone: Fax: Email: Website:

UK Contact

Dr Helen Stebbens Quarry Cottage Easton Wells Somerset BA5 1EE

+32 2 778 1411 +32 2 771 8287 info.europe@novusint.com www.novusint.com

Tel/Fax: Email:

™GLYTREX is a trademark of Novus International, Inc.

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+44 1749 870862 helen.stebbens@novusint.com

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Glytrex™ Mn Presentation

new

Glytrex™ Mn is an organic form of the trace element manganese. It is a white-beige powder containing:

• Minimum 15% by weight Manganese (from Manganese Chelate of Glycine Hydrate)

• Minimum 43% by weight Glycine

Use

Glytrex™ Mn should be fed continuously as a component of a complete diet at the following inclusion rates:

Cattle Broilers Turkeys Layers Ducks Swine Equine Goats

1

1.0g per head per day1 135-270g/tonne of complete feed1 135-270g/tonne of complete feed1 135-270g/tonne of complete feed1 135-270g/tonne of complete feed1 65-130g/tonne of complete feed1 1.0g per head per day1 0.1g per head per day1

Or as directed by a qualified nutritionist

Storage

A shelf life of 24 months as from date of manufacture can be achieved if the product is stored at ambient temperature in a sealed container and in dry conditions.

Package sizes

25kg bags

Supplier

Novus Europe SA/NV Avenue Marcel Thiry 200 1200 Brussels Belgium

Telephone: Fax: Email: Website:

UK Contact

Dr Helen Stebbens Quarry Cottage Easton Wells Somerset BA5 1EE

+32 2 778 1411 +32 2 771 8287 info.europe@novusint.com www.novusint.com

Tel/Fax: Email:

+44 1749 870862 helen.stebbens@novusint.com

™GLYTREX is a trademark of Novus International, Inc.

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Glytrex™ Zn Presentation

new

Glytrex™ Zn is an organic form of the trace element zinc. It is a white-beige powder containing:

• Minimum 15% by weight Zinc (from Zinc Chelate of Glycine Hydrate)

• Minimum 35% by weight Glycine

Use

Glytrex™ Zn should be fed continuously as a component of a complete diet at the following inclusion rates:

Cattle Broilers Turkeys Layers Ducks Swine Equine Sheep/Goats

1

2.4g per head per day1 135-270g/tonne of complete feed1 135-270g/tonne of complete feed1 135-270g/tonne of complete feed1 135-270g/tonne of complete feed1 135-270g/tonne of complete feed1 2.4g per head per day1 0.5g per head per day1

Or as directed by a qualified nutritionist

Storage

A shelf life of 24 months as from date of manufacture can be achieved if the product is stored at ambient temperature in a sealed container and in dry conditions.

Package sizes

25kg bags

Supplier

Novus Europe SA/NV Avenue Marcel Thiry 200 1200 Brussels Belgium

Telephone: Fax: Email: Website:

UK Contact

Dr Helen Stebbens Quarry Cottage Easton Wells Somerset BA5 1EE

+32 2 778 1411 +32 2 771 8287 info.europe@novusint.com www.novusint.com

Tel/Fax: Email:

™GLYTREX is a trademark of Novus International, Inc.

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+44 1749 870862 helen.stebbens@novusint.com

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Grindazym™ GP 15000 G Presentation

Grindazym GP 15000 G is supplied as a light-brown fine granular product. Bulk weight: 800kg/m³ Moisture content: 12%

Use

Grindazym GP 15000 G is a feed enzyme system specifically developed to improve the nutritional value of poultry and weaned piglet diets.

Dosage/administration

Broilers: Use at a rate of 0.135-0.167kg/tonne of complete feed. Turkeys: Use at a rate of 0.167kg/tonne of complete feed. Ducks: Use at a rate of 0.167kg/tonne of complete feed. Piglets: Use at a rate of 0.167kg/tonne of complete feed. Use and Dosage/administration is subject to individual registration. For specific details contact supplier.

Package sizes

25kg multi-wall paper sacks, polythene lined and 1,000kg bulk (tote) bags.

Further information

Guaranteed minimum activity: 15000 units beta-glucanase/g (IUB No. EC 3.2.1.4), 36000 units xylanase/g (IUB No. EC 3.2.1.8). Analysis methods detailing assay conditions are available upon request. Stability and storage: For optimum bioefficacy, do not exceed conditioning and pelleting temperatures of 80°C. Grindazym GP 15000 G is stable for 24 months when stored in original packaging at ≤ 20°C and for 6 months when included in a vitamin/mineral premix. Store in dry conditions. Safety and purity: Available on request. There are no producing micro-organisms in the final product. None of the ingredients is of animal origin. Handling: Provide for good ventilation and avoid dust formation. It is recommended to use protective glasses, respiratory mask and gloves during handling. In case of accidental contact with skin or eyes, the only action needed is copious flushing with water. See the Material Safety Data Sheet for further information.

Legal category

Enzyme

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Supplier

Danisco Animal Nutrition PO Box 777 Marlborough Wiltshire SN8 1XN Tel: Fax: E-mail: Web:

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01672 517777 01672 517778 info.animalnutrition@danisco.com www.danisco.com/animalnutrition

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Grindazym™ GPL 15000 Presentation

Grindazym GPL 15000 is supplied as a yellow to brown liquid. Specific Gravity: Viscosity: Freezing Point: pH:

1.12-1.14g/ml 3.0 cPs at 24°C -5°C 4.5-5.0

◊ Use

Grindazym GPL 15000 is a liquid feed enzyme system specifically developed to improve the nutritional value of poultry and weaned piglet diets.

Dosage/administration

Broilers: Use at a rate of 0.135-0.167kg/tonne of complete feed. Must apply post-pelleting. Turkeys: Use at a rate of 0.167kg/tonne of complete feed. Must apply post-pelleting. Ducks: Use at a rate of 0.167kg/tonne of complete feed. Must apply post-pelleting. Piglets: Use at a rate of 0.167kg/tonne of complete feed. Must apply post-pelleting. Use and Dosage/administration is subject to individual registration. For specific details contact supplier.

Package sizes

Containers of 230kg and 1000kg.

Further information

Guaranteed minimum activity: 15000 units beta-glucanase/g (IUB No. EC 3.2.1.4), 36000 units xylanase/g (IUB No. EC 3.2.1.8). Analysis methods detailing assay conditions are available upon request. Stability and storage: For any processing conditions, particularly where conditioning and pelleting temperatures exceed 80°C. Grindazym™ GPL 15000 is stable for 9 months when stored in original packaging at ≤10°C. Do not freeze. Safety and purity: Available on request. There are no producing micro-organisms in the final product. None of the ingredients is of animal origin. Handling: Provide for good ventilation and avoid aerosol formation. It is recommended to use protective glasses, respiratory mask and gloves during handling. In case of accidental contact with skin or eyes, the only action needed is copious flushing with water. See the Material Safety Data Sheet for further information.

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Legal category

Enzyme

Supplier

Danisco Animal Nutrition PO Box 777 Marlborough Wiltshire SN8 1XN Tel: Fax: E-mail: Web:

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01672 517777 01672 517778 info.animalnutrition@danisco.com www.danisco.com/animalnutrition

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Hostazym XÂŽ liquid Presentation

Light-brown liquid formulation of enzymes for incorporation into feedstuffs for oral administration. Hostazym X has as its activity the breakdown of arabino-xylans. Hostazym X100 contains 15000 EPU (Endo Pentosanase Units) per gram, Hostazym X250 contains 6000 EPU (Endo Pentosanase Units) per gram and Hostazym X500 contains 3000 EPU (Endo Pentosanase Units) per gram of product.

Uses

Hostazym is added to feed to help break down macro-molecules in feed into absorbable nutrients, and to help break down antinutritional factors such as Non Starch Polysaccharides in feed. Hostazym allows the feed to contain higher than normal levels of wheat and barley. Hostazym C and Hostazym X are both capable of providing these benefits to feeds containing high levels of either or both wheat and barley, but where an obvious bias is known, high barley diets should contain Hostazym C in preference and high wheat diets should contain Hostazym X in preference.

Dosage/administration

Recommended dosages in final feed of broilers are: Hostazym X100 liquid 0.1litres/tonne Hostazym X250 liquid 0.25 litres/tonne Hostazym X500 liquid 0.5 litres/tonne

Recommended dosages in final feed of turkeys are: Hostazym X100 liquid 0.07litres/tonne Hostazym X250 liquid 0.175 litres/tonne

Contra-indications, warnings, etc.

Operators handling the product should wear face mask, gloves and protective clothing and to avoid inhalation of and contact with the product. If Hostazym accidentally enters the operatorâ&#x20AC;&#x2122;s eyes, rinse out with water immediately. Wash hands and exposed skin after handling the product.

Withdrawal period

None.

Legal category

Enzyme/micro-organism product

EU authorisation

E1617

Package quantities

1000 litre IBC Containers.

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Further information

Activity in finished feed At an inclusion rate of 0.1 litres/tonne of Hostazym X100, 0.25 litres/tonne of Hostazym X250 or 0.5 litres/tonne of Hostazym X500, the finished feed will contain 1500 EPU/kg feed. At an inclusion rate of 0.07 litres/tonne of Hostazym X100, 0.175 litres/tonne of Hostazym X250 or 0.5 litres/tonne of Hostazym X500, the finished feed will contain 1050 EPU/kg feed.

Supplier

Huvepharma NV Uitbreidingstraat 80 2600 Antwerp Belgium Tel: Fax: Email: Web:

0032 3 288 1849 0032 3 289 7845 customerservice@huvepharma.com www.huvepharma.com

速Registered trade mark.

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Hostazym X® microGranulate Presentation

Light-brown microgranulated formulation of enzymes for incorporation into feedstuffs for oral administration. Hostazym X has as its activity the breakdown of arabino-xylans. Hostazym X100 contains 15000 EPU (Endo Pentosanase Units) per gram, Hostazym X250 contains 6000 EPU (Endo Pentosanase Units) per gram and Hostazym X500 contains 3000 EPU (Endo Pentosanase Units) per gram of product.

Uses

Hostazym is added to feed to help breakdown macro-molecules in feed into absorbable nutrients, and to help breakdown antinutritional factors such as Non Starch Polysaccharides in feed. Hostazym allows the feed to contain higher than normal levels of wheat and barley. Hostazym C and Hostazym X are both capable of providing these benefits to feeds containing high levels of either or both wheat and barley, but where an obvious bias is known, high barley diets should contain Hostazym C in preference and high wheat diets should contain Hostazym X in preference.

Dosage/administration

Recommended dosages in final feed of broilers are: Hostazym X100 microGranulate 0.1kg/tonne Hostazym X250 microGranulate 0.25kg/tonne Hostazym X500 microGranulate 0.5kg/tonne

Recommended dosages in final feed of turkeys are: Hostazym X100 microGranulate 0.07kg/tonne Hostazym X250 microGranulate 0.175kg/tonne

Contra-indications, warnings, etc.

Operators handling the product should wear face mask, gloves and protective clothing and to avoid inhalation of and contact with the product. If Hostazym accidentally enters the operator’s eyes, rinse out with water immediately. Wash hands and exposed skin after handling the product.

Withdrawal period

None.

Pharmaceutical precautions

Temperatures above 85°C during pelleting may reduce the enzymatic activity of Hostazym microGranulate.

Legal category

Enzyme/micro-organism product

EU authorisation

E1617

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Package quantities

25kg multi-walled, PE-lined paper bags.

Further information

Activity in finished feed At an inclusion rate of 0.1kg/tonne of Hostazym X100, 0.25kg/ tonne of Hostazym X250 or 0.5kg/tonne of Hostazym X500, the finished feed will contain 1500 EPU/kg feed. At an inclusion rate of 0.07kg/tonne of Hostazym X100, 0.175kg/tonne of Hostazym X250 or 0.5kg/tonne of Hostazym X500, the finished feed will contain 1050 EPU/kg feed.

Supplier

Huvepharma NV Uitbreidingstraat 80 2600 Antwerp Belgium Tel: Fax: Email: Web:

0032 3 288 1849 0032 3 289 7845 customerservice@huvepharma.com www.huvepharma.com

速Registered trade mark.

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Hostazym® Suis Presentation

Light-brown microgranulated formulation of enzymes for incorporation into feedstuffs for oral administration. Hostazym Suis has as its activity the breakdown of non starch polysaccharides and contains mainly endo-1,4-β-glucanase, pentosanase, hemicellulase, α-amylase and protease produced by Trychoderma longibrachiatum. Hostazym Suis 2000 contains 2000 CU (cellulase units) per gram and Hostazym Suis 5000 contains 5000 CU (cellulase units) per gram.

Uses

Hostazym Suis is added to feed to help breakdown macromolecules in feed into absorbable nutrients, and to help breakdown anti-nutritional factors such as Non Starch Polysaccharides in feed. Hostazym Suis allows the feed to contain higher than normal levels of wheat and barley.

Dosage/administration

Recommended dosages in final feed of pigs are: Hostazym Suis 2000 CU/g Weaned piglets up to 35kg bodyweight

0.175kg/tonne

Hostazym Suis 5000 CU/g Weaned piglets up to 35kg bodyweight

0.07kg/tonne

Contra-indications, warnings, etc.

Operators handling the product should wear face mask, gloves and protective clothing and to avoid inhalation of and contact with the product. If Hostazym Suis accidentally enters the operator’s eyes, rinse out with water immediately. Wash hands and exposed skin after handling the product.

Withdrawal period

None.

Pharmaceutical precautions

Temperatures above 85°C during pelleting may reduce the enzymatic activity of Hostazym Suis.

Legal category

Enzyme/micro-organism product

EU authorisation

E1616

Package quantities

25kg multi-walled, PE-lined paper bags.

Further information

Activity in finished feed At an inclusion rate of 0.175kg/tonne of Hostazym Suis 2000 CU/g or 0.07kg/tonne of Hostazym Suis 5000 CU/g, the finished feed will contain 350 CU/kg feed.

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Supplier

Huvepharma NV Uitbreidingstraat 80 2600 Antwerp Belgium Tel: Fax: Email: Web:

0032 3 288 1849 0032 3 289 7845 customerservice@huvepharma.com www.huvepharma.com

速Registered trade mark.

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INNOZYM DELTA (L)

Presentation

INNOZYM DELTA (L) is a liquid carbohydrase preparation produced by submerged fermentation of an Aspergillus aculeatus microorganism. It contains endo-1,3:1,4- β-glucanase (IUB No. 3.2.1.6), pentosanase, hemicellulase and pectic-substance hydrolysing activities. The specific weight is approximately 1.2g/ml.

Appearance: brown aqueous liquid

Fungal β-glucanase activity: 120 FBG/ml (minimum).

Uses

INNOZYM DELTA (L) has been demonstrated to be effective in improving the utilisation of feeds for broiler chickens, which is rich in hemicellulose derived from cereals and vegetable proteins.

◊ Dosage/administration

100-600g per tonne of feed, sprayed onto the pellets after cooling.

Contra-indications, warnings, etc.

This product is safe for the intended use. Avoid ingestion or direct contact by applying suitable protective measures and personal hygiene.

For full safety information and necessary precautions, please refer to the respective Material Safety Data Sheet.

Further information

Stability and storage INNOZYM DELTA (L) is sensitive to heat. The product maintains its declared activity for at least six months when stored in the unopened original container and at a temperature below 25°C. Prolonged storage at temperatures above 30°C should be avoided. The date of manufacture is indicated on the container.

Legal category

Enzyme/micro-organism product.

Package quantities

1,200kg IBCs

Supplier

Frank Wright Trouw Nutrition International Blenheim House Blenheim Road Ashbourne Derbyshire DE6 1HA Tel: Fax: Email: Website:

01335 341101 01335 341167 customer.services@frankwright.com www.frankwrighttrouw.com

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INNOZYM KAPPA (L)

Presentation

INNOZYM KAPPA (L) is a liquid amylolytic enzyme preparation produced by submerged fermentation of a Bacillus amyloliquefaciens micro-organism. It is used for the improvement of starch digestibility in cereal-based feeds. INNOZYM KAPPA (L) contains a mixture of α-amylase (IUB No. 3.2.1.1) and endo1,3:1,4-β-glucanase (IUB No. 3.2.1.6). The specific weight is approximately 1.12g/ml.

Appearance: brown, aqueous liquid α-Amylase activity: 130 KNU/ml (minimum) Endo-β-glucanase activity: 225 FBG/ml (minimum)

Uses

INNOZYM KAPPA (L) has been demonstrated to be effective in improving the utilization of feeds for broiler chickens, which is rich in starch and non-starch polysaccharides (NSPs), mainly β-glucans.

◊ Dosage/administration

86-689g per tonne of feed, sprayed onto the pellets after cooling.

Contra-indications, warnings, etc.

This product is safe for the intended use. Avoid ingestion or direct contact by applying suitable protective measures and personal hygiene.

For full safety information and necessary precautions, please refer to the respective Material Safety Data Sheet.

Further information

Stability and storage INNOZYM KAPPA (L) is sensitive to heat. The declared activity is maintained for at least four months from the date of manufacture when the product is stored in the unopened original container and at a temperature below 25°C. Prolonged storage at temperatures above 30°C should be avoided. The date of manufacture is indicated on the container.

Legal category

Enzyme/micro-organism product.

Package quantities

1,000kg IBCs

Supplier

Frank Wright Trouw Nutrition International Blenheim House Blenheim Road Ashbourne Derbyshire DE6 1HA Tel: Fax: Email: Website:

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INNOZYM PHYTASE (L)

Presentation

INNOZYM PHYTASE (L) is a liquid phytase preparation (IUB No. 3.1.3.26) from Peniophora lycii produced by submerged fermentation of a genetically modified Aspergillus oryzae micro-organism. The specific weight is approximately 1.2g/ml. The colour may vary from batch to batch, and colour intensity is not an indication of product strength.

Appearance: brown aqueous liquid

Phytase activity: 5000 FYT/g (minimum)

Uses

INNOZYM PHYTASE (L) is effective in improving the utilisation of feeds for broiler chickens, laying hens, turkeys, ducks, piglets, fattening pigs and sows, which contain phytate phosphorus.

◊ Dosage/administration

60-240g per tonne of feed, sprayed onto the pellets after cooling.

Contra-indications, warnings, etc.

This product is safe for the intended use. Avoid ingestion or direct contact by applying suitable protective measures and personal hygiene.

For full safety information and necessary precautions, please refer to the respective Safety Data Sheet.

Further information

Stability and storage INNOZYM PHYTASE (L) maintains its declared activity for at least six months from the date of manufacture when stored in the unopened original container and at a temperature below 25°C. Prolonged storage at temperatures above 30°C should be avoided. The date of manufacture is indicated on the container.

Legal category

Enzyme/micro-organism product.

Package quantities

1,000kg IBCs

Supplier

Frank Wright Trouw Nutrition International Blenheim House Blenheim Road Ashbourne Derbyshire DE6 1HA Tel: Fax: Email: Website:

01335 341101 01335 341167 customer.services@frankwright.com www.frankwrighttrouw.com

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INNOZYM WHEAT (L)

Presentation

INNOZYM WHEAT (L) is a liquid, heat-stable endo-xylanase from Thermomyces lanuginosus, produced by submerged fermentation of a genetically modified Aspergillus oryzae micro-organism. The main activity is endo-1,4-β-xylanase (IUB No. 3.2.1.8). The specific weight is approximately 1.12g/ml.

Appearance: brown aqueous liquid

Fungal xylanase activity: 650 FXU (W) per ml (minimum)

Uses

INNOZYM WHEAT (L) has been demonstrated to be effective in improving the utilization of feeds for broilers chickens, turkeys, ducks and piglets which are rich in non-starch polysaccharides (NSPs), mainly arabinoxylans.

◊ Dosage/administration

172-689g per tonne of feed, sprayed onto the pellets after cooling.

Contra-indications, warnings, etc.

This product is safe for the intended use. Avoid ingestion or direct contact by applying suitable protective measures and personal hygiene.

For full safety information and necessary precautions, please refer to the respective Material Safety Data Sheet.

Further information

Stability and storage INNOZYM WHEAT (L) maintains its declared activity for at least four months from the date of manufacture at a temperature below 25°C, and for at least 12 months from the date of manufacture at a temperature below 5°C, when stored in the unopened original container. Prolonged storage at temperatures above 30°C should be avoided. The date of manufacture is indicated on the container.

Legal category

Enzyme/micro-organism product.

Package quantities

1,000kg IBCs

Supplier

Frank Wright Trouw Nutrition International Blenheim House Blenheim Road Ashbourne Derbyshire DE6 1HA Tel: Fax: Email: Website:

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Handbook of Feed Additives 2009 Handbook of Feed Additives 2009 is one of several directories, periodicals and reports published by Simon Mounsey Ltd. Amongst our other titles for feed producers and their suppliers are: • Feed Statistics 2009 • Feed Businesses 2009 • Feed Industry Review Details about these and other publications and services can be found on our website at: www.simonmounsey.com

Updates to this Handbook can also be found on the same website. You can go directly to the updates site at the following address: www.simonmounsey.com/hbupdate.htm

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IVOMEC® 0.6% Premix FOR PIGS Presentation

A clean, free flowing non-dusty, slightly yellow to light brown fine fibrous meal mixture containing 0.6% w/w ivermectin, for incorporation into animal feeding stuffs.

Uses

IVOMEC 0.6% Premix for Pigs is an in-feed endectocide indicated for the treatment and control of gastro-intestinal roundworms, lungworms, lice and mange in adult and growing pigs. The product provides control against the following parasites of pigs: Gastro-intestinal worms: Adult and immature stages of Ascaris suum, Hyostrongylus rubidus, Oesophagostomum spp. and Strongyloides ransomi (adults only)* Lungworms: Metastrongylus spp. (adults) Lice: Haematopinus suis. Mange mites: Sarcoptes scabiei var. suis *IVOMEC 0.6% Premix for Pigs given to pregnant sows before farrowing effectively controls transmission via the milk of S. ransomi to piglets. Since louse eggs can take up to three weeks to hatch, re-treatment may be necessary. Since the effect of ivermectin is not immediate, avoid contact between treated and untreated pigs for at least one week after completion of the treatment programme. Exposure of treated pigs to infected animals, contaminated premises, soil or pasture may result in reinfection.

Dosage/administration

IVOMEC 0.6% Premix for Pigs must be incorporated in feed and fed for seven consecutive days at the recommended dose rate of 100 micrograms of ivermectin per kg of bodyweight per day. The appropriate inclusion rate of Premix, in kg per tonne of feed, can be calculated using the following formula: IVOMEC 0.6% Premix for Pigs inclusion rate (kg/tonne of feed) = 0.1 × average bodyweight (kg) 6 x average daily feed intake (kg)

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Using the above formula some commonly used inclusion rates of IVOMEC 0.6% Premix for Pigs required for different groups of pigs are as follows: a) Growing pigs (up to 40kg) consuming 5% of their bodyweight in feed per day: 333g IVOMEC 0.6% Premix for Pigs/tonne. The IVOMEC 0.6% Premix for Pigs must be thoroughly mixed in the finished feed, and fed continuously as the only ration for seven consecutive days b) Growing pigs over 40kg. Average daily feed consumption may fall below 5% of bodyweight, particularly if they are on a restricted feeding programme or where pigs are fed a high protein ration. The inclusion rate should be adjusted accordingly using the formula above c) Adult pigs consuming 1% of their bodyweight in feed per day: 1.67kg IVOMEC 0.6% Premix for Pigs/tonne. The resulting medicated feed should be fed at a rate of 1kg per 100kg of bodyweight each day for seven days. Where medicated feed is fed as part of the ration, it is recommended that the IVOMEC medicated feed is fed first. After this is consumed, any remaining daily feed allocation should be given. This should be repeated for seven consecutive days. Alternatively, where dry feed intake can be accurately measured and all the animals to be treated have a similar bodyweight, the inclusion rate can be calculated using the previous formula. This assumes the total ration is to be medicated. IVOMEC 0.6% Premix for Pigs can be administered to sows at any stage of pregnancy or lactation. IVOMEC 0.6% Premix for Pigs can be used in breeding sows and boars and will not affect fertility. Recommended treatment programmes: a) Growing pigs. Groups of growing pigs should be treated for seven consecutive days on transfer to clean quarters. Where an all-in-all-out system is not possible, it is recommended that the parasite control programme should start with all the growing pigs already in the house. b) Adult pigs. All breeding pigs should be treated in a blanket programme every 6â&#x20AC;Żmonths or as often as necessary. A treatment will be of particular use before moving sows to clean quarters or a fresh paddock.

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Contra-indications, warnings etc

For animal treatment only. Do not smoke or eat while handling the product. Wash hands after use. Do not use for any other animal species as severe adverse reactions, including fatalities in dogs, may occur.

Withdrawal periods

Animals must not be slaughtered for human consumption during treatment.

Meat withdrawal period: three days for pigs under 100kg bodyweight and twelve days for pigs over 100kg bodyweight.

Container disposal

EXTREMELY DANGEROUS TO FISH AND AQUATIC LIFE. Do not contaminate surface waters or ditches with product or used containers. Drug containers and any residual contents should be disposed of in accordance with any guidance from an appropriate waste regulation authority.

Pharmaceutical precautions

Store below 25°C in a dry place. To ensure thorough dispersion of the product, it should first be mixed with a suitable quantity of feed ingredients before incorporation in the final mix. The product will remain stable in finished feed for three months when stored below 25°C in a dry place. It can be incorporated in pelleted feed preconditioned with steam for up to ten seconds at a temperature not exceeding 85°C. Keep out of reach of children

Legal category

POM-VPS

Package quantities

5 kg multiple wall bags with a polyethylene liner.

Further information

When used as recommended, this product should only be incorporated by Category A manufacturers.

Marketing authorisation number

Vm 08327/4168

Marketing authorisation holder

Merial Animal Health Ltd Sandringham House P O Box 327 Harlow Essex CM19 5TG Tel: 01279 775858 Fax: 01279 775888 Customer Support Centre: Freephone 0800 592699 ® Registered trademark of Merial Limited

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KokcisanÂŽ 120G

new

Presentation

Brownish granulate with characteristic odour containing salinomycin sodium 120g/kg.

Uses

As an aid in the prevention of coccidiosis in broiler chickens caused by Eimeria tenella, E. necatrix, E. acervulina, E. maxima, E. brunetti and E. mivati.

Dosage/administration

500-538g of Kokcisan 120G should be mixed per tonne of complete feed. This results in a final concentration of 60-70g salinomycin sodium per tonne of feed (60-70mg/kg).

Contra-indications, warnings, etc.

Birds must not be slaughtered for human consumption during treatment or for at least three days after the last treatment. Birds should not be treated with products containing tiamulin while receiving, or for at least seven days before or after receiving feed containing this product. Severe growth depression or death may result. For use in broiler chickens only. Dangerous for equines and turkeys. Do not mix with feeds containing any other coccidiostat. Operators should avoid direct contact with the product or inhalation. Wear face masks to at least the specification of BS 2091, impervious gloves and protective overalls when handling. Rinse eyes thoroughly with water immediately if eye contact occurs. For animal treatment only. Keep out of reach of children.

Pharmaceutical precautions

Do not store over 25°C. Protect from light and humidity. To ensure thorough dispersion, the product should first be mixed with 5 to 10 times its weight of feed before incorporation in the final mix. The product will remain stable in finished feed for three months.

Legal category

Specified feed additive (coccidiostat)

European authorisation number: E766

Package quantities

25kg net in polythene-lined multi-walled paper bags.

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Supplier

KRKA, d.d., Novo mesto Šmarješka cesta 6 8501 Novo mesto Slovenia

Tel: Fax: Web:

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+386 1 4751 100 +386 1 4751 411 www.krka.si 

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Lincocin* Premix Presentation

A free-flowing premix for inclusion in animal feeding stuffs. Each kg contains lincomycin (as lincomycin hydrochloride) 44g in a soya bean mill feed carrier.

Uses

For the treatment and control of swine dysentery and mycoplasmal pneumonia.

Dosage/administration

For the control of swine dysentery: feed 44g of lincomycin per tonne (1,000kg) of complete feed as the sole ration throughout the period of risk. For the treatment of swine dysentery: feed 110g of lincomycin per tonne (1,000kg) of complete feed as the sole ration for three weeks or until clinical signs of disease (watery, mucoid or bloody stools) disappear. For the treatment and control of swine mycoplasmal pneumonia: feed 220g of lincomycin per tonne (1,000kg) of complete feed as the sole ration for three weeks or until clinical signs of disease disappear. For the inappetant pig: where individual pigs are not readily taking Lincocin Premix medicated feed, it is advisable that parenteral administration of Lincocin Sterile Solution (100mg/ml) should be employed at a dose rate of 10mg/kg bodyweight daily. One or two intramuscular injections at a 24 hour interval will normally control clinical signs adequately to return the appetite. Where medication via the drinking water is more applicable, Lincocin Soluble Powder may be administered at the recommended rate of 150mg lincomycin per 4.5 litres (1 gallon) of drinking water.

Mixing directions

For the control of swine dysentery: to make complete feed containing 44g lincomycin per tonne, add 1kg of Lincocin Premix per 1,000kg. For the treatment of swine dysentery: to make complete feed containing 110 ppm of lincomycin, add 2.5kg of Lincocin Premix per 1,000kg. For the treatment and control of swine mycoplasmal pneumonia: to make complete feed containing 220g of lincomycin per tonne, add 5kg of Lincocin Premix per tonne (1,000kg).

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To ensure thorough dispersion of the product, it should first be mixed with a suitable quantity of feed before incorporation into the final mix. When incorporated at less than 2kg/tonne, this product should only be incorporated by Category A manufacturers. Incorporation into pig feeding stuffs must follow the product licence directions given above or be in accordance with a Medicated Feedingstuffs Prescription. Contra-indications, warnings, etc.

Do not use in animals with known hypersensitivity to lincomycin. Clinical antagonism may exist between lincomycin and erythromycin and concurrent use is therefore not recommended. Animals must not be slaughtered for human consumption during treatment. Withdrawal periods for the different dosing regimes are as shown below: Indication Dosage

Withdrawal Period

Swine dysentery

44g or 110g lincomycin 24 hours per tonne of feed

Swine mycoplasmal pneumonia

220g lincomycin per tonne of feed

3 days

Occasionally, pigs fed lincomycin may, within the first two days after the onset of treatment, develop soft stools and/or mild swelling of the anus. On rare occasions some pigs may show skin irritation and mild irritable behaviour. These conditions are usually self-correcting within five to eight days without discontinuing the lincomycin treatment. Operator warning: Avoid inhaling dust and avoid skin contact when using the product. Wash hands and exposed skin after work. Keep out of reach of children. For animal treatment only. Pharmaceutical precautions

Store below 25째C. Store opened bag in dry place to prevent caking. The product will remain stable in the medicated final feed for three months.

Legal category

POM-V

Package quantities

Supplied in 2.5kg polyethylene-lined polyester bags and 25kg polyethylene-lined paper bags.

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Further information

Dispose of according to local or national requirements e.g. licensed waste disposal contractor.

Marketing authorisation number

Vm 00057/4232

Marketing authorisation holder

Pfizer Limited Ramsgate Road Sandwich Kent CT13 9NJ

Tel: Fax: *

(01304) 616161 (01737) 332521

Lincocin is a registered trade mark.

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Linco-Spectin* Premix Presentation

Each kg contains 22g lincomycin (as lincomycin hydrochloride) and 22g spectinomycin (as spectinomycin sulphate) in a soya bean mill feed carrier.

Uses

For the control and treatment of enteritis associated with Lawsonia intracellularis (ileitis) in pigs.

For the control and treatment of swine dysentery caused by Serpulina hyodysenteriae associated with Fusobacterium, Bacteroides, Clostridium and/or Campylobacter spp. sensitive to the combination lincomycin and spectinomycin. For the control and treatment of enteritis in pigs caused by E. coli and Salmonella spp. sensitive to the combination lincomycin and spectinomycin. The product has been shown to be particularly effective against complicated or mixed enteric infections involving the above organisms. As an aid in the control of mycoplasmal (enzootic) pneumonia in pigs. For the treatment of Mastitis, Metritis, Agalactiae (MMA) syndrome of bacterial origin sensitive to the combination lincomycin and spectinomycin in sows. The product is active in vitro against Serpulina hyodysenteriae, Bacteroides spp., Fusobacterium spp., Clostridium spp., Escherichia coli, Salmonella spp., Campylobacter spp., staphylococci, streptococci and mycoplasmas.

Dosage/administation

For oral administration only.

Treatment of enteric conditions: Add 2kg product per tonne of feed and feed daily for three weeks or until clinical signs disappear. Control of enteric conditions: Add 1-2kg product per tonne of feed and feed daily throughout the period of risk. As an aid in the control of mycoplasmal pneumonia: Add 12kg product per tonne of feed and feed daily throughout the period of risk. Treatment of MMA: Add 1-2kg product per tonne of feed and feed daily for 5-10 days prior to farrowing and 2-3 weeks postfarrowing.

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To ensure thorough dispersion, the product should first be mixed with a suitable quantity of feed before incorporation in the final mix. A Category A manufacturer must be responsible for mixing when incorporation is less than 2kg per tonne of final feed. This product has been shown to be clinically compatible with salinomycin. Contra-indications, warnings, etc.

Withdrawal period: Animals must not be slaughtered for human consumption during treatment. Pigs may be slaughtered for human consumption only after two days from last treatment. Warnings: Loosening of faeces and/or mild swelling of the anus may occur; this is usually transient. On rare occasions, mild irritability and reddening of skin may occur. These conditions are usually self-correcting within five to eight days without discontinuing therapy. If clinical signs are not improved during the first ten days of medication, discontinue treatment and redetermine the diagnosis. Dispose of any unused and empty containers in accordance with guidance from your local waste regulation agency. Operator warnings: Persons known to be hypersensitive (allergic) to lincomycin, spectinomycin or soybean millfeed should not handle this product. Care should be taken not to inhale any dust. The wearing of approved dust masks (either disposable half-mask respirator conforming to European Standard EN149 or a non-disposable respirator to European Standard EN140 with a filter to EN143) and safety glasses is recommended during the handling and mixing of this product. Skin contact should be avoided. Wash hands and any exposed skin with soap and water immediately after use. Keep out of reach of children. For animal treatment only.

Pharmaceutical precautions

Do not store above 25째C. Store in a dry place. Store opened bag in a dry place to prevent caking. The product can be incorporated into pelleted feed at a processing temperature not exceeding 70째C. The product will remain stable in finished feed and in pelleted feed for three months.

Legal category

POM-V

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Package quantities

2kg and 20kg multi-wall bags

Further information

Nil

Marketing authorisation number

Vm 00057/4233

Marketing authorisation holder

Pfizer Limited Ramsgate Road Sandwich Kent CT13 9NJ

Tel: Fax:

(01304) 616161 (01737) 332521

速Trade mark

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Lucantin® Yellow

Presentation

A free-flowing powder, consisting of yellow-orange particles containing 100g β-apo-8’-carotenoic acid ethylester per kg for incorporation into animal feeds.

Uses

Apocarotene ester occurs in nature as a metabolic product of apocarotinal, which can be extracted from grass, lucerne, green vegetables and citrus fruits. The carotenoids are principally used in animal nutrition for colouring egg yolks, broiler skin and fish flesh. Lucantin® Yellow is primarily used in combination with Lucantin® Red, **Lucantin® CX Forte and other carotenoids to provide an acceptable yolk or broiler skin colour.

◊ Dosage/administration

Mix the appropriate quantity of Lucantin® Yellow into feed to achieve the required yolk and broiler skin colour. The normally small addition rate of this pigment means that addition is preferred in a suitable premix to effect satisfactory dispersion in feed. The quantity required will depend on the background level of pigmentation from feed ingredients and the level of Lucantin® Red or **Lucantin® CX Forte added to the feed to achieve a suitable egg yolk or broiler skin colour. The recommended levels of addition of Lucantin® Yellow are shown in the following tables.

Table 1: Lucantin® Yellow and Lucantin® Red dosage recommendations for broiler skin pigmentation Natural Xanthophyll content in feed (eg from corn, alfalfa etc)

Expected Pigmentation medium to good

very good

Lucantin® Yellow

Lucantin® Yellow

Lucantin® Yellow

Lucantin® Red

mg/kg

g/tonne

g/tonne

10

150 - 200

290

or

210

+

50

15

120 - 170

260

or

180

+

50

g/tonne

g/tonne

20

90 - 140

230

or

150

+

50

25

60 - 100

200

or

120

+

50

30

30 - 70

170

or

90

+

50

35

0 - 40

140

or

60

+

50

40

-

110

or

30

+

50

45

-

80

or

0

+

50

** Lucantin® CX Forte is not suitable for broiler skin pigmentation.

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Table 2: Lucantin® Yellow, Lucantin® Red and Lucantin® CX Forte for egg yolk pigmentation dosage recommendations for laying hen diet (based on BASF colour fan, 2001) Contents of natural Supplement of: yellow-colouring carotenoids mg/kg of feed (ppm)

0-2

2-4

4-6

6-8

8 - 10

10-12

12-16

> 16

Contra-indications/ precautions

Supplements of Lucantin® dry powder in g/tonne of feed for an intended value of the colour scale of:

6

7

8

9

10

11

12

13

14

15

20

25

25

25

25

30

30

30

35

35

-

-

8

15

23

38

53

75

90

105

15

20

20

20

20

20

25

25

30

30

-

-

8

15

23

38

53

75

90

105

10

15

15

15

20

20

20

20

25

30

Lucantin® CX Forte

-

-

8

15

23

38

53

75

90

105

Lucantin® Yellow

5

10

10

10

15

15

15

20

20

25

Lucantin® CX Forte

-

-

8

15

23

38

53

75

90

105

Lucantin® Yellow

0

0

0

0

0

0

0

10

15

15

Lucantin® CX Forte

-

-

8

15

23

38

53

75

90

105

Lucantin® Yellow

0

0

0

0

0

0

0

0

10

10

Lucantin® CX Forte

-

-

8

15

23

38

53

75

90

105

Lucantin® Yellow

0

0

0

0

0

0

0

0

0

0

Lucantin® CX Forte

-

-

-

8

23

38

53

75

90

105

Lucantin® Yellow

0

0

0

0

0

0

0

0

0

0

Lucantin® CX Forte

-

-

-

8

15

38

53

75

90

105

Lucantin® Yellow Lucantin® CX Forte Lucantin® Yellow Lucantin® CX Forte Lucantin® Yellow

For animal use only. Store in a cool dry place. When mixing and handling Lucantin® Yellow, use protective clothing, impervious gloves and a dust mask.

Legal category

Carotenoids and xanthophylls.

Packaging sizes

25kg box.

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Supplier

BASF Group PO Box 4 Earl Road Cheadle Hulme Cheshire SK8 6QG Tel: Fax: Website:

Contact

0161 485 6222 0161 485 5487 www.animal-nutrition.basf.com

Brian Pope Telephone: 01772 603119 Email: brian.pope@basf.com

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Lucantin® CX Forte Presentation

A free-flowing powder, consisting of reddish brown particles containing 100g citranaxanthin per kg for incorporation into animal feeds.

Uses

The carotenoids are principally used in animal nutrition for colouring egg yolks, broiler skin and fish flesh. Lucantin® CX Forte is primarily used in combination with Lucantin® Yellow or other carotenoids to provide an acceptable yolk colour.

Dosage/administration

Mix the appropriate quantity of Lucantin® CX Forte into feed to achieve the required yolk colour. The normally small addition rate of this pigment means that addition is preferred in a suitable premix to effect satisfactory dispersion in feed. The quantity required will depend on the background level of pigmentation from feed ingredients and the level of carotenoid added to the feed to achieve a suitable yellow to yellow orange colour of egg yolks. The recommended levels of addition of Lucantin® CX Forte are shown in Tables 1 and 2 on pages 192 and 193.

Contra-indications/ precautions

For animal use only. Store in a cool dry place. When mixing and handling Lucantin® CX Forte, use protective clothing, impervious gloves and a dust mask.

Legal category

Carotenoids and xanthophylls.

Packaging sizes

25kg box.

Supplier

BASF Group PO Box 4 Earl Road Cheadle Hulme Cheshire SK8 6QG Tel: Fax: Website:

Contact

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0161 485 6222 0161 485 5487 www.animal-nutrition.basf.com

Brian Pope Telephone: 01772 603119 Email: brian.pope@basf.com

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Lucarotin® 10% Feed

new

Presentation

A free-flowing, red to red-brown powder containing 100g ß-Carotene per kg.

Uses

Lucarotin® 10% Feed is suitable for all types of vitamin blends, premixes, mineral and mixed feeds. The flowability and mixing behaviour of the product are excellent and guarantee homogeneous mixing in all types of feed.

Dosage/administration

ß-Carotene occurs in nature, in particular in green plants. In addition to the varying amounts in individual plant feedstuffs, climate harvesting, degree of wilting, type of preservation (drying, ensiling) and storage time affect the content.

Investigations in recent years show that ß- carotene has a positive effect on the fertility process of male and female cattle. Comparable investigations also exist for other animal species such as breeding mares, sows and rabbits. It was also possible to observe an increase in the powers of resistance against infectious rearing diseases in young animals.

Dosage recommendations Animal Species

Carotene Dosage (mg/animal/day)

Start

End

Dairy cow

200

3 weeks before calving

on discovery of new pregnancy

400

1 week before weaning

up to mating

200

after mating

on discovery of new pregnancy

Breeding mare

500

4 weeks before foaling

10 weeks after foaling

Breeding rabbits

10-20 (mg/kg of compound feed)

Breeding sow

Contra-indications/ precautions

For animal use only. The product is safe for the intended use. Avoid ingestion, inhalation of dust or direct contact by applying suitable protective measures. For full safety information and necessary precautions, please refer to the respective BASF Material Safety Data Sheets.

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Additive functional group

Vitamins, pro-vitamins and chemically well-defined substances having a similar effect.

Packaging sizes

25kg cardboard box with Alu/PE bag.

Further information

The active substance Ă&#x;-carotene is present in Lucarotin 10% Feed in a biologically highly active form. The processing of this product should therefore be carried out using the customary care in terms of occupational hygiene. The provisions of the safety data sheet are to be observed.

Supplier

BASF Group PO Box 4 Earl Road Cheadle Hulme Cheshire SK8 6QG Tel: Fax: Website:

Contact

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0161 485 6222 0161 485 5487 www.animal-nutrition.basf.com

Brian Pope Telephone: 01772 603119 Email: brian.pope@basf.com

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Lupro-Mix® NC Presentation

A colourless to yellowish liquid organic acid mixture with faint characteristic odour, completely miscible in water at a pH of 4.0 (at 100g/litre H2O). Contains 38% propionic acid, 34% formic acid, 8% ammonium and 20% H2O.

Uses

Both formic acid and propionic acid are well known to have nutritional efficacy. It has been shown in many experiments that the advantages of the two acids in this respect are combined extremely well in this Lupro-Mix® NC product. The optimisation of feed hygiene provides maximum protection against alimentary intake of fungi, bacteria and yeasts. The digestion of the feed is therefore beneficially influenced by these acid mixtures in several ways resulting in improved growth and feed efficiency and reduced digestive disorders. In addition to feed preservation effects, Lupro-Mix® NC is an effective way to reduce buffering capacity in baby pig diets, reducing and stabilising gut pH and inhibiting the growth of pathogenic bacteria. As a consequence, there is an improvement in gastro-intestinal health, which results in enhanced growth performance and feed utilisation with lower incidence of digestive disorders. The inclusion of water and ammonium in this product reduces the corrosiveness associated with straight acid products, making the product easier to handle and ideal for use as an acidifier to drinking water of pigs and poultry.

◊ Dosage/administration

Lupro-Mix® NC should be added at the time of mixing final feed. Lupro-Mix® NC can also be added to liquid feeding systems. The following doses are recommended for Lupro-Mix® NC in the various stages of growth and types of stock:

Lupro-Mix® NC inclusion (kg/t)

Pig creep/starter

8-10

Pig link

8-10

Pig grower/finisher

5-8

Sow

7-8

Broiler

3-5

Turkey

5-8

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Actual optimum dose level will vary depending upon the age of the animal, type of feed ingredients, buffering capacity of the diet, microbiological contamination and moisture content of the feed. Contra-indications/ precautions

For animal use only. Can be used through the whole life cycle â&#x20AC;&#x201C; NO WITHDRAWAL PERIOD REQUIRED. This acid mixture is corrosive. Only corrosive resistant materials must be used for storage and transport. Acid resistant gloves and tightly fitting goggles must be worn when handling this acid mixture. In case of contact, immediately remove contaminated clothing and wash skin thoroughly with clean cold water.

Packaging sizes

1000kg IBCs.

Legal category

Preservative

Supplier

BASF Group PO Box 4 Earl Road Cheadle Hulme Cheshire SK8 6QG Tel: Fax: Website:

Contact

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0161 485 6222 0161 485 5487 www.animal-nutrition.basf.com

Brian Pope Telephone: 01772 603119 Email: brian.pope@basf.com

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Keep this Handbook up-to-date! When this Handbook was published, in February 2009, everything possible had been done by the publisher and product suppliers to ensure the information contained was accurate and up-to-date. Inevitably, some products will be subject to important changes between publication of this edition and the next. Whenever we are notified of changes to product information contained in this edition, these changes will be posted on our website at: www.simonmounsey.com/hbupdate.htm The updates will be in the form of replacement pages which can be printed out and used to replace pages in the original. As an additional service to users of this book, you may register to receive notification whenever an updated page is posted. Simply send an email to mail@simonmounsey.com with the subject line â&#x20AC;&#x153;Handbook Updates 2009â&#x20AC;? and your email address for notification.

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Lutalin™ Presentation

Oily, colourless to slightly yellowish clear liquid.

Use

Lutalin contains 28% +/- 1% omega 6 fatty acids.

Dosage/administration

The dosage recommendations for complete feed specified below are based on current scientific knowledge and prolonged experience.

Pig grower/finisher:

0.5% in compound feed

Breeding sows:

0.5% in compound feed

Contra-indications/ precautions

For animal use only.

Packing sizes

Available in 175 kg drums.

Additive functional group

Vitamins, pro-vitamins and chemically well-defined substances having a similar effect.

Further information

The product has a shelf-life of 18 months when stored in the unopened original package. Store at room temperature in airtight drums under nitrogen headspace. Do not store at temperatures above 40°C. Some precipitation may occur below 20°C. Lutalin has a melting point of approximately 5°C. If the product does not flow, gently warm product above 30°C and agitate before use. Reseal properly after use.

Supplier

BASF Group PO Box 4 Earl Road Cheadle Hulme Cheshire SK8 6QG

Precautions The product is safe for the intended use. Omega 6 fatty acids are biologically active compounds. For further instructions see product safety data sheet.

Tel: Fax: Website: Contact

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Brian Pope Telephone: 01772 603119 Email: brian.pope@basf.com

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Lutavit A 1000 Plus Presentation

Brownish, free-flowing powder.

Use

Lutavit A 1000 Plus is suitable for all types of vitamin blends, premixes, mineral and mixed feeds. The flowability and mixing behavior of the product are excellent and guarantee homogeneous mixing in all types of feed.

Dosage/administration

The dosage recommendations for complete feeds specified below are based on current scientific knowledge and prolonged experience.

Broilers, layers, turkeys: Piglets: Pig grower/finisher: Breeding sows: Dairy cows:

Contra-indications/ precautions

For animal use only.

Packing sizes

Available in 20kg PE bag and 500kg flexible IBC.

Additive functional group

Vitamins, pro-vitamins and chemically well-defined substances having a similar effect.

Further information

Lutavit A 1000 Plus is sensitive to air, heat, light and humidity. The product may be stored for 12 months from the date of manufacture in the unopened original container and at a temperature below 15째C. The best used before date is printed on the label. Keep container tightly closed. Once opened, use contents quickly. The stability of vitamin A in mixed and mineral feeds or premixes has to be assessed as somewhat less than in the commercial product. Especially in mixtures of active mineral ingredients, the stability of vitamin A can be impaired by a trace element content which is often high. Above all, trace elements containing water of crystallisation contribute to reduced vitamin A stability, which can be further effected by a high moisture content of the total mixture. Even technological processes in the formulation of mixed feeds such as pelleting and extrusion exert a negative influence on the stability of vitamin A.

EU authorisation

Lutavit A 1000 Plus is permanently approved as E672 for all kinds of livestock species, companion animals and fish.

The product is safe for the intended use. Avoid ingestion, inhalation of dust or direct contact by applying suitable protective measures. For full safety information and necessary precautions, please refer to the respective BASF Material Safety Data Sheets.

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8,000-12,000 IU/kg 12,000-20,000 IU/kg 8,000-12,000 IU/kg 16,000-20,000 IU/kg 80,000-140,000 IU per animal per day

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Supplier

BASF Group PO Box 4 Earl Road Cheadle Hulme Cheshire SK8 6QG Tel: Fax: Website:

Contact

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0161 485 6222 0161 485 5487 www.animal-nutrition.basf.com

Brian Pope Telephone: 01772 603119 Email: brian.pope@basf.com

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Lutavit B2 SG 80 Plus Presentation

Orange-yellow, fine, free-flowing granules of characteristic odour.

Use

Lutavit B2 SG 80 is suitable for all types of vitamin blends, premixes, mineral and mixed feeds. The flowability and mixing behaviour of the product are excellent and guarantee homogeneous mixing in all types of feed.

Dosage/administration

The dosage recommendations for complete feeds specified below are based on current scientific knowledge and prolonged experience.

Broilers: Turkeys: Layers: Piglets: Pig grower/finisher: Breeding sows:

Contra-indications/ precautions

For animal use only.

Packing sizes

Available in 25kg PE bag, 500kg flexible IBC and in bulk.

Additive functional group

Vitamins, pro-vitamins and chemically well-defined substances having a similar effect.

Further information

Lutavit B2 SG 80 may be stored for 36 months from the date of manufacture in the unopened original container and at a temperature below 15째C. The best used before date is printed on the label. Keep container tightly closed. Lutavit B2 SG 80 is not substantially affected by air, but it is sensitive to alkaline substances, especially in the presence of oxygen. The product should be protected from light and atmospheric moisture.

EU authorisation

Lutavit B2 SG 80 is permanently approved for all kinds of livestock species, companion animals and fish.

The product is safe for the intended use. Avoid ingestion, inhalation of dust or direct contact by applying suitable protective measures. For full safety information and necessary precautions, please refer to the respective BASF Material Safety Data Sheets.

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5-7mg/kg 6-8mg/kg 5-8mg/kg 5-7mg/kg 3-6mg/kg 5-7mg/kg

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Supplier

BASF Group PO Box 4 Earl Road Cheadle Hulme Cheshire SK8 6QG Tel: Fax: Website:

Contact

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0161 485 6222 0161 485 5487 www.animal-nutrition.basf.com

Brian Pope Telephone: 01772 603119 Email: brian.pope@basf.com

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Lutavit Calpan Presentation

Fine, white to almost white, free-flowing granulate.

Use

Lutavit Calpan is suitable for all types of vitamin blends, premixes, mineral and mixed feeds. The flowability and mixing behaviour of the product are excellent and guarantee homogeneous mixing in all types of feed.

Dosage/administration

The dosage recommendations for complete feeds specified below are based on current scientific knowledge and prolonged experience.

Broilers: Turkeys: Layers: Piglets: Pig grower/finisher: Breeding sows:

Contra-indications/ precautions

For animal use only.

Packing sizes

Available in 25kg PE bag and in 500kg flexible IBC.

Additive functional group

Vitamins, pro-vitamins and chemically well-defined substances having a similar effect.

Further information

Lutavit Calpan may be stored for 36 months from the date of manufacture in the unopened original container and at a temperature below 15째C. The best used before date is printed on the label. Keep container tightly closed. Lutavit Calpan is highly stable to the effects of atmospheric oxygen and light.

EU authorisation

Lutavit Calpan is permanently approved for all kinds of livestock species, companion animals and fish.

The product is safe for the intended use. Avoid ingestion, inhalation of dust or direct contact by applying suitable protective measures. For full safety information and necessary precautions, please refer to the respective BASF Material Safety Data Sheets.

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10-12mg/kg 10-15mg/kg 8-10mg/kg 12-16mg/kg 8-14mg/kg 12-16mg/kg

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Supplier

BASF Group PO Box 4 Earl Road Cheadle Hulme Cheshire SK8 6QG Tel: Fax: Website:

Contact

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0161 485 6222 0161 485 5487 www.animal-nutrition.basf.com

Brian Pope Telephone: 01772 603119 Email: brian.pope@basf.com

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Lutavit E 50 Presentation

Fine, white to off-white, free-flowing powder.

Use

Lutavit E 50 is suitable for all types of vitamin blends, premixes, mineral and mixed feeds. The flowability and mixing behaviour of the product are excellent and guarantee homogeneous mixing in all types of feed.

Dosage/administration

The dosage recommendations for complete feeds specified below are based on current scientific knowledge and prolonged experience.

Broilers, turkeys: Layers: Piglets: Pig grower/finisher: Breeding sows: Dairy cows:

Contra-indications/ precautions

For animal use only.

Packing sizes

Available in 25kg PE bag, 25kg cardboard box with PE bag and 500kg flexible IBC.

Additive functional group

Vitamins, pro-vitamins and chemically well-defined substances having a similar effect.

Further information

Lutavit E 50 may be stored for 24 months from the date of manufacture in the unopened original container and at a temperature below 15째C. The best used before date is printed on the label. Keep container tightly closed. Once opened, use contents quickly. In mixtures, vitamin E losses can occur depending on the composition (for example higher trace elements content) and the production and storage conditions (pelleting, action of heat). These active substance losses are particularly important in the presence of strong vitamin stress factors (moisture, choline chloride, trace elements) and in alkaline medium (high contents of magnesium oxide).

EU authorisation

Lutavit E 50 is permanently approved for all kinds of livestock species, companion animals and fish.

The product is safe for the intended use. Avoid ingestion, inhalation of dust or direct contact by applying suitable protective measures. For full safety information and necessary precautions, please refer to the respective BASF Material Safety Data Sheets.

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30-50mg/kg 20-30mg/kg 80-120mg/kg 40-80mg/kg 60-80mg/kg 500-1,000mg per animal per day

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Supplier

BASF Group PO Box 4 Earl Road Cheadle Hulme Cheshire SK8 6QG Tel: Fax: Website:

Contact

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0161 485 6222 0161 485 5487 www.animal-nutrition.basf.com

Brian Pope Telephone: 01772 603119 Email: brian.pope@basf.com

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Lutrell® Pure Presentation

Off-white to beige free-flowing granulate.

Use

Lutrell Pure is a rumen-protected formulation of omega 6 fatty acids. It is suitable for all types of vitamin blends, premixes, mineral and mixed feeds.

Contains 10% Omega 6 fatty acids.

Dosage/administration

The dosage recommendations for complete feeds specified below are based on current scientific knowledge and prolonged experience.

Dairy cows: 50g per animal per day during the first 80 to 150 days post calving. Duration of treatment should cover the period of most severe negative energy balance.

Contra-indications/ precautions

For animal use only.

Packing sizes

Available in 25kg PE bag.

Additive functional group

Vitamins, pro-vitamins and chemically well-defined substances having a similar effect.

Further information

Lutrell pure has a shelf life of 12 months in the unopened original package at less than room temperature. Do not store above 25°C. Some caking caused by the fat coating could occur if stored abaove 25°C or if stored under weight pressure. Reseal bags properly after use.

Supplier

BASF Group PO Box 4 Earl Road Cheadle Hulme Cheshire SK8 6QG

The product is safe for the intended use. Omega 6 fatty acids are biologically active compounds. The processing of the granulate should therefore be carried out with the customary care in terms of occupational hygiene. On contact, the provisions of the safety data sheet are to be observed.

Tel: Fax: Website: Contact

0161 485 6222 0161 485 5487 www.animal-nutrition.basf.com

Brian Pope Telephone: 01772 603119 Email: brian.pope@basf.com

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MacroGard®

new

Presentation

MacroGard® is a pure natural product derived from bakers’ yeast (Saccharomyces cerevisiae), containing pure β 1,3/1,6-glucans.

Product information

Active Component Pure β 1,3/1,6-glucans

Uses

Specification Carbohydrates: 60% (guaranteed minimum)

Dosage/administration

Varies according to animal species, age, bodyweight and application. For the correct dosage, please refer to Orffa in the first instance.

Further information

Shelf life 2 years from date of production.

Package quantities

25kg cartons with polyethylene inliner.

Supplier

Orffa Additives BV Vierlinghstraat 51 4251 LC Werkendam The Netherlands

Orffa UK Office PO Box 113 Northallerton North Yorkshire DL6 1YH

Tel: +31 (0) 183 44 77 44 Fax: +31 (0) 183 44 30 60 E-mail: info@orffa.com Website: www.orffa.com

Tel: +44 (0) 1609 772881 Fax: +44 (0) 1609 780941

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β 1,3/1,6-glucans are reported to modulate the immune system of young animals and animals under high pathogenic pressure or undergoing stress. β 1,3/1,6-glucans are also reported to be an adjuvant to support vaccination programmes.

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Maxiban速 G160 Presentation

Maxiban G160 is a free-flowing mixture of tan-yellow and grey-brown granular particles for incorporation into animal feedingstuffs. Each 1kg of Maxiban G160 contains 80g of narasin and 80g of nicarbazin activity.

Uses

As an aid in the prevention of coccidiosis in broiler chickens caused by Eimeria acervulina, E. brunetti, E. maxima, E. necatrix and E. tenella.

Dosage/administration

Dilute the required amount of Maxiban G160 with at least five times its own weight (minimum 20kg) of a suitable feed ingredient prior to incorporation into the bulk of the feed. Thoroughly mix 500 to 625g of Maxiban G160 per tonne of feed ingredients to produce a complete feed containing 80 to 100g total active ingredients per tonne (40g narasin and 40g nicarbazin to 50g narasin and 50g nicarbazin per tonne).

Contra-indications, warnings, etc.

For animal treatment only. Keep out of reach of children. Maxiban G160 should be carefully mixed with the mineral supplement or other feed ingredients prior to feed manufacture to ensure even distribution in the final feed. For use in feeds intended for broiler chickens only. Do not feed to turkeys or other avian species, or to chickens producing eggs. Dangerous for equines. Do not allow horses or other equines access to feeds containing Maxiban G160. Ingestion of narasin by horses has been fatal. This product must not be mixed or used simultaneously with any other coccidiostat. Poultry must not be slaughtered for human consumption during treatment or for at least five days after the last treatment. Avoid contact with skin and eyes. When mixing and handling Maxiban G160, use protective clothing, impervious gloves and a disposable half mask respirator conforming to BS2091 Type A. Operators should wash thoroughly with soap and water after handling.

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If accidental eye contact occurs, immediately rinse thoroughly with water. Animals, including birds, should not be treated with products containing tiamulin while receiving, or for at least seven days before or after receiving, feed containing Maxiban G160. Severe growth depression or death may result. To be used exclusively by manufacturers of premixtures for compound feedingstuffs. Pharmaceutical precautions

Maxiban G160 should be stored in a cool, dry place. For shelf life see expiry date on label. Maxiban G160 is stable in finished feed, including pelleted feed for up to three months.

Legal category

Specified feed additive (coccidiostat).

Package quantities

Laminated paper/woven polyethylene sacks containing 25kg.

Further information

Nil.

European authorisation number

772

Supplier

Elanco Animal Health Lilly House Priestley Road Basingstoke Hampshire RG24 9NL

Tel: Fax:

ÂŽMaxiban â&#x20AC;&#x201C; registered trade mark for narasin and nicarbazin, Eli Lilly and Company Ltd.

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(01256) 353131 (01256) 779510

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MERI-BOND Xtra Chemical name

Clinoptilolite â&#x20AC;&#x201C; a natural zeolite.

Presentation

Ivory coloured powder.

Uses

Toxin binder and anti-caking agent for animal feeds.

Reduces ammonia levels in the animalâ&#x20AC;&#x2122;s digestive tract and faeces.

Minimises odour.

Usage/administration

1-6kg per tonne of finished feed or as directed by your nutritionist. Mycotoxin prevention: 2-4kg per tonne of feed. Mycotoxin control and removal: 4-6kg per tonne of feed. SiO2

Silica

71.0%

Chemical analysis and physical properties

Al2O3

Alumina

11.8%

Fe2O3

Ferric oxide

1.7 %

MgO

Magnesium oxide

1.4%

CaO

Calcium oxide

3.4%

Na2O

Sodium oxide

0.4%

K2O

Potassium oxide

2.4%

TiO2

Titanium dioxide

0.10%

Specific weight:

200-2400kg/m3

Volume weight:

1260-19060kg/m3

Hardness:

Porosity:

49.3%

Abrasion:

87mg/100g

2-3 Mohs

Water absorbing capacity:

Oil absorbing capacity:

Cation exchange capacity:

Legal category

Binders, anti-caking agents and coagulants.

Package quantities

25kg multi-layer paper bags with inner PE lining.

Storage

Keep cool and dry.

Expiry: two years from manufacture.

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46.5% 57mg/100g 1.5-1.8meq/g

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Supplier

Meriden Animal Health Limited Cranfield Innovation Centre University Way Cranfield Technology Park Cranfield MK43 0BT Tel: Fax: Email: Web:

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+44(0)1234 436130 +44(0)1234 436131 sales@meriden-ah.com www.meriden-ah.com

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Handbook of Feed Additives 2009 Handbook of Feed Additives 2009 is one of several directories, periodicals and reports published by Simon Mounsey Ltd. Amongst our other titles for feed producers and their suppliers are: • Feed Statistics 2009 • Feed Businesses 2009 • Feed Industry Review Details about these and other publications and services can be found on our website at: www.simonmounsey.com

Updates to this Handbook can also be found on the same website. You can go directly to the updates site at the following address: www.simonmounsey.com/hbupdate.htm

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MERI-PHYZE 5000 Presentation

Yellow, free-flowing granules containing myo-inositol hexaphosphate phosphohydrolase with a minimum phytase activity of 5000 FTU/g.

Uses

To increase the digestibility and convertibility of plant phosphorus present in the diet.

Usage/administration

Pigs

100g per tonne to give 500 FTU/kg

Broilers

100g per tonne to give 500 FTU/kg

Layers

60g per tonne to give 300 FTU/kg

Turkeys

100g per tonne to give 500 FTU/kg

Precautions

Caution should be taken when handling this product. Avoid inhalation or direct contact with skin or eyes as it may cause allergies in sensitive individuals. If this happens, wash eyes and/or affected area thoroughly with water.

Legal category

Enzyme/Micro-organism product.

Package quantities

20kg carton.

Storage

Store in a cool, dry place (less than 20째C). Close container after use.

Supplier

Meriden Animal Health Limited Cranfield Innovation Centre University Way Cranfield Technology Park Cranfield MK43 0BT Tel: Fax: Email: Web:

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+44(0)1234 436130 +44(0)1234 436131 sales@meriden-ah.com www.meriden-ah.com

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Monteban速 G100 Presentation

A dark grey-brown free-flowing granular premix speckled with light tan to yellow particles for incorporation into animal feedingstuffs. Each kg of premix contains narasin equivalent to 100g of narasin activity.

Uses

Indications: As an aid to the prevention of coccidiosis in broiler chickens caused by Eimeria acervulina, E. brunetti, E. maxima, E. necatrix and E. tenella.

Dosage/administration

Mix the appropriate quantity of Monteban G100 to obtain the recommended levels of narasin, with 20-50kg of a suitable feed component prior to incorporation into the bulk of the feed to be prepared. Monteban G100 should be mixed thoroughly into broiler feeds at a level of 600-700g per tonne. This will provide narasin at a level equivalent to 60-70g narasin activity per tonne. Feed containing Monteban G100 should be fed continuously to broiler chickens until one day before slaughter for human consumption.

Contra-indications, warnings, etc.

For animal treatment only. Keep out of reach of children. Monteban G100 should be carefully mixed with the mineral supplement or other feed ingredients prior to the feed being manufactured to ensure even distribution in the final feed. For use in feeds intended for broiler chickens only. Do not feed to turkeys, guinea fowl, other avian species or to chickens producing eggs. Do not allow horses or other equines access to feed containing Monteban G100, ingestion of narasin by horses has been fatal. This product must not be mixed with another coccidiostat described as such in the annexes to Directive 70/524. Poultry must not be slaughtered for human consumption during treatment or for at least one day after the last treatment. When mixing and handling Monteban G100, use protective clothing, impervious gloves and a dust mask. Operators should wash thoroughly, with soap and water after handling.

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If accidental eye contact occurs, immediately rinse thoroughly with water. Animals, including birds, should not be treated with products containing tiamulin while receiving, or for at least seven days before or after receiving, feed containing Monteban G100. Severe growth depression or death may result. Pharmaceutical precautions

Store in a cool, dry place. For shelf life, see expiry date on label.

Legal category

Specified feed additive (coccidiostat).

Package quantities

25kg in laminated paper/woven polyethylene sacks.

Further information

When used as recommended this product should only be incorporated by non-farm mixers.

European authorisation number

765

Supplier

Elanco Animal Health Lilly House Priestley Road Basingstoke Hampshire RG24 9NL

Tel: Fax:

ÂŽMonteban â&#x20AC;&#x201C; registered trade mark for narasin, Eli Lilly and Company Ltd.

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Natugrain® Wheat TS Presentation

An enzyme preparation originating from fungal fermentation (Aspergillus niger), Natugrain® Wheat TS is a yellowish-brown powder with a minimum of 5,600 units/g of thermo stable endo-xylanase activity (TXU*/g). This product has excellent flow properties and is free of dust. * TXU = Thermo stable endo xylanase unit

Uses

Natugrain® Wheat TS has been developed especially for poultry feed mixtures containing a high content of wheat and wheat by-products such as wheat bran, to achieve improved bird performance through high biological effectiveness. Improvements can also be expected in rye-containing diets.

Dosage/administration

For optimal performance, the recommended dosage rate of wheatbased and/or rye-containing diets is 100ppm. The economical optimal dosage rate for your diet, however, varies depending on the wheat/rye content of the diet and is influenced by the raw material costs of the diet (specific registration requirements have to be respected).

Further information

Mixing Natugrain® Wheat TS with vitamin or mineral premixes can cause activity losses due to interactions with certain components such as choline chloride and some trace elements. Under cool and dry storage conditions, premixes can be stored up to three months and still retain the labelled activity. The pelleting stability of an enzyme depends on several factors. Use of Natugrain® Wheat TS is possible up to a pelleting temperature of 85°C (measured directly at the pellet press). However, the quantity of added steam in the conditioner and duration of the conditioning process significantly influences the pelleting stability of an enzyme.

Package sizes

20kg bags.

Legal category

Enzyme/micro-organism product

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Precautions

As exogenous proteins, enzymes may cause allergic reactions in particularly sensitised people. This applies in particular to persons who are prone to developing allergies or have already shown allergic reactions to foreign protein. When handling enzymes, the formation of aerosols and dust should be avoided. In addition, it is recommended that gloves, dust masks and respiratory equipment be worn. These safety precautions should also be observed when Natugrain速 Wheat TS is used. For details see the Safety Data Sheet for Natugrain速 Wheat TS.

Supplier

BASF Group PO Box 4 Earl Road Cheadle Hulme Cheshire SK8 6QG Tel: Fax: Website:

Contact

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0161 485 6222 0161 485 5487 www.animal-nutrition.basf.com

Brian Pope Telephone: 01772 603119 Email: brian.pope@basf.com

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Natuphos® 5000 L Presentation

Yellowish, brown liquid containing myo-inositol hexaphosphate 3-phosphohydrolase with a minimum phytase activity of 5000 FTU/g.

Uses

Natuphos® 5000 L increases the digestibility and convertibility of plant phosphorus present in the diet. Consequently, more phosphorus is available for absorption in the small intestine of monogastric animals and a lower P content of the feed is required in order to cover the animal’s phosphorus requirement. In pigs and poultry phosphorus excretion in the manure is thus reduced. Besides the effect with phosphorus, Natuphos® also improves the digestibility and utilisation of other minerals like Ca, Mg and Zn. Furthermore, it improves the digestibility of proteins and amino acids. In poultry, it is possible to measure a positive effect on the trend in live weight.

Dosage/administration

On the basis of experience in practice to date, about 0.10 to 0.12 per cent of the phosphorus previously added to pig and poultry rations should be replaced by the equivalent quantities of phytase given below:

Inclusion (g/t) Phytase activity Species Natuphos® 5000L (FTU/kg)

Total P (g/kg) released from MCP

Total P (g/kg) released from DCP (18%) 1.15

Pigs

100

500

1.00

Broilers

100

500

1.00

1.15

Layers

60-80

300-400

1.67

1.91

Turkeys

100

500

1.00

1.15

Precautions

Phytase ‑ like other enzymes ‑ is a biologically highly active substance. As exogenous proteins, enzymes may cause allergic reactions in particularly sensitised people. For this reason, when the liquid is sprayed onto feed pellets the formation of aerosols should be prevented and exposure of operatives avoided. The instructions of the safety data sheets should be observed.

Legal category

Enzyme/micro-organism product

Further information

Stability It is recommended that Natuphos® L is stored under cool and dry conditions. In the closed original container, Natuphos® L is adequately stable in appropriate storage for four months. The container should be carefully closed again after removal of part of its contents.

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Use of Natuphos® liquid For hygienic reasons, compound feed for pigs and poultry is often exposed to high temperatures during pelleting. Comparatively high temperatures also occur during processes such as expansion and extrusion. If phytase is added to the mash feed there may be, as for other enzymes, great losses of activity, depending on the subsequent hydrothermal stress. If, during pelleting, the temperature of the treated meal exceeds 80°C, use Natuphos 5000® L, which can be sprayed onto the feed pellets downstream of the cooler. For spraying the pellets it is advisable to have a slow‑running screw, a spraying drum or a continuously or discontinuously operating mixer. Because of the small amount of Natuphos® L sprayed on it is possible to dilute it with water to meet the minimum dose rate required legally or technically. It is advisable in this case to use a two‑component nozzle for mixing immediately before actual use. If premixes are made up they should not be stored for lengthy periods because microbial spoil and thus loss of phytase activity may occur. After phytase has been sprayed onto the pellets, abrasion should be minimised in further treatment of them to avoid losses of product. Investigations to date on sprayed feed pellets at room temperature have revealed losses not exceeding 5% over four weeks. Packaging sizes

1000kg IBC.

Supplier

BASF Group PO Box 4 Earl Road Cheadle Hulme Cheshire SK8 6QG Tel: Fax: Website:

Contact

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0161 485 6222 0161 485 5487 www.animal-nutrition.basf.com

Brian Pope Telephone: 01772 603119 Email: brian.pope@basf.com

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Natuphos® 10000 G

new

Presentation

Fine, white granules containing myo-inositol hexaphosphate phosphohydrolase with a minimum phytase activity of 10,000 FTU/g.

Uses

Natuphos®10000 G increases the digestibility and convertibility of plant phosphorus present in the diet. Consequently, more phosphorus is available for absorption in the small intestine of monogastric animals and a lower P content of the feed is required in order to cover the animal’s phosphorus requirement. In pigs and poultry phosphorus excretion in the manure is thus reduced.

Dosage/administration Inclusion (g/t) Phytase activity Species Natuphos® 10000G (FTU/kg)

Total P (g/kg) released from MCP

Total P (g/kg) released from DCP (18%)

Pigs

50

500

1.00

1.15

Broilers

50

500

1.00

1.15

Layers

30

300

1.67

1.91

Turkeys

50

500

1.00

1.15

Ducks

50

500

1.00

1.15

Precautions

Phytase – like other enzymes – is a biologically highly active substance. As exogenous proteins, enzymes may cause allergic reactions in particularly sensitised people. The processing of the products should therefore be carried out with the customary care in terms of occupational hygiene. Dust formation should be prevented when mixing Natuphos®, or exposure of the employees should be avoided. When the product has been spilled or come into contact with skin or eyes, rinse affected area thoroughly with water. The instructions of the safety data sheets should be observed.

Legal category

Enzyme/micro-organism product

Packaging sizes

20kg bags.

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Supplier

BASF Group PO Box 4 Earl Road Cheadle Hulme Cheshire SK8 6QG Tel: Fax: Website:

Contact

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0161 485 6222 0161 485 5487 www.animal-nutrition.basf.com

Brian Pope Telephone: 01772 603119 Email: brian.pope@basf.com

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Optimin速 SeY EU

new

Presentation

Optimin SeY EU is a free-flowing, light-brown/tan powder.

Optimin SeY EU is an inactivated whole cell yeast product, enriched in selenium and produced with a specific yeast strain (Saccharomyces cerevisiae NCYC R397). Optimin SeY Eu contains the nutritionally essential trace element selenium mostly in the L(+) selenomethionine form. It is produced with a specific process by growing the yeast strain in a controlled medium containing selenium. The yeast biochemically transforms inorganic selenium and naturally accumulates it as L(+) selenomethionine. This is the natural nutritional source of selenium, found in plant proteins, but only at very low concentration. It is considered to be the most suitable form of selenium for animal nutrition, from its ability to provide a consistent supply of this nutrient to the animal, allowing for incorporation to its final functions when needed.

Specification Ash Moisture Protein Selenium Selenomethionine

6-8% < 7% min. 50% 2,000-2,400ppm (97-99% organic selenium) typically 2,900-3,500ppm

Uses

Optimin SeY EU is used as a nutritional supplement of selenium for livestock and fish diets. Optimin SeY EU is designed to effectively prevent nutritional disorders related to selenium supply.

Dosage/administration

Species

Selenium1 Optimin SeY EU

Pigs:

Piglets

0.3ppm

150g/tonne

Fattening Pigs

0.1ppm

50g/tonne

Sows

0.3ppm

150g/tonne

0.3ppm

150g/tonne

Broilers: Starters

Growers

0.2ppm

100g/tonne

Finishers

0.2ppm

100g/tonne

Layers

0.2ppm

100g/tonne

Poultry Breeding stock

0.3ppm

150g/tonne

Beef cattle

0.2ppm

100g/tonne

Dairy Cattle

0.3ppm

150g/tonne

Fish

0.2ppm

100g/tonne

1

Total selenium in feed materials from all sources must not exceed 0.5ppm.

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Further information

Stability Optimin SeY EU is stable in pelleting and extrusion processes.

Storage Store in a dry place in original packaging and protect from humidity.

Legal category

Nutritional feed additive.

EU authorisation

Optimin SeY EU is authorised in the EU for use in all animal species (EC N째3b8.11).

Package quantities

25kg multi-wall paper bag with LDPE inner liner.

Supplier

Frank Wright Trouw Nutrition International Blenheim House Blenheim Road Ashbourne Derbyshire DE6 1HA Tel: Fax: Email: Website:

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01335 341101 01335 341167 customer.services@frankwright.com www.frankwrighttrouw.com

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OREGO-STIM® Liquid Presentation

A milky, off-white, 100% natural liquid containing oregano essential oil as active substance.

Uses

OREGO-STIM® is an animal feed additive with a distinctive aroma that serves as a feed flavour, appetite enhancer, can assist in times of stress and has other interesting properties.

Usage/administration

For administration in the drinking water. Inclusion rates vary according to conditions. For specific advice contact your nutritionist, veterinarian, distributor or Meriden technical staff. The following rates are given as a guide: POULTRY Use OREGO-STIM® Liquid at 300ml per 1000 litres of water throughout the first week and during critical periods. At all other times, use OREGO-STIM® Liquid at 150ml per 1000 litres of water. When used together with OREGO-STIM® Powder at 300g per tonne of feed, use OREGO-STIM® Liquid at 150ml per 1000 litres of water throughout the first week and during critical periods. PIGS Creep feed up to 15 days postweaning: 500ml per 1000 litres of water 15 days postweaning to 25kg bodyweight: 250ml per 1000 litres of water 25kg bodyweight to slaughter: 125ml per 1000 litres of water Gestating and lactating sows: 125ml per 1000 litres of water RUMINANTS Beef Cattle: An initial 500ml per 1000 litres of water for 28 days, followed by maintenance rate at 125ml per 1000 litres of water.

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Dairy Cattle: 15ml per head per day for 28 days once diarrhoea is seen. Sheep and Goats: An initial 500ml per 1000 litres of water for 28 days, followed by maintenance rate at 125ml per 1000 litres of water. Compatibility

OREGO-STIM速 is 100% natural and therefore compatible with all other types of feed additive.

Contra-indications, warnings, etc.

Do not use in undiluted form.

Pharmaceutical precautions

No withdrawal period necessary. Store in a cool, dry place, out of direct sunlight. Close container securely after use. Shake well before use.

Packaging

1 litre bottles.

Origin

Produced in the United Kingdom in FEMAS certificated production facilities.

Legislation

The active components within OREGO-STIM速 are classified by the USFDA as GRAS (Generally Recognised As Safe) substances. OREGO-STIM速 is registered within the European Union as a feed additive complying with Regulation (EC) Number 1831/2003.

Supplier

Meriden Animal Health Limited Cranfield Innovation Centre University Way Cranfield Technology Park Cranfield MK43 0BT Tel: Fax: Email: Web:

+44(0)1234 436130 +44(0)1234 436131 sales@meriden-ah.com www.orego-stim.com www.meriden-ah.com

OREGO-STIM速 is a registered trade mark of Meriden Animal Health Limited

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OREGO-STIM速 Powder Presentation

A light-brown, free-flowing, 100% natural powder containing oregano essential oil as active substance.

Uses

OREGO-STIM速 is an animal feed additive with a distinctive aroma that serves as a feed flavour, appetite enhancer, can assist in times of stress and has other interesting properties.

Usage/administration

For administration in the feed. Inclusion rates vary according to conditions. For specific advice contact your nutritionist, veterinarian, distributor or Meriden technical staff. The following rates are given as a guide: POULTRY Continuously at 300g per tonne of feed. To achieve best results, this product should be supplemented with the use of OREGO-STIM速 Liquid at 150ml per 1000 litres of water throughout the first week and during critical periods. PIGS Creep feed up to 15 days postweaning: 1kg per tonne of feed 15 days postweaning to 25kg bodyweight: 500g per tonne of feed 25kg bodyweight to slaughter: 250g per tonne of feed Gestating and lactating sows: 250g per tonne of feed RUMINANTS Beef Cattle: An initial 1kg per tonne of feed for 28 days, followed by maintenance rate at 250g per tonne of feed. Dairy Cattle: 15g per head per day for 28 days once diarrhoea is seen. Sheep and Goats: An initial 1kg per tonne of feed for 28 days, followed by maintenance rate at 250g per tonne of feed.

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Compatibility

OREGO-STIM速 is 100% natural and therefore compatible with all other types of feed additive.

Contra-indications, warnings, etc.

Not to be fed direct.

Pharmaceutical precautions

No withdrawal period is necessary. Store in a cool, dry place, out of direct sunlight. Close container securely after use.

Packaging

5 x 5kg or 25kg packed in high quality foil packs within a heavy duty box.

Origin

Produced in the United Kingdom in FEMAS certificated production facilities.

Legislation

The active components within OREGO-STIM速 are classified by the USFDA as GRAS (Generally Recognised As Safe) substances. OREGO-STIM速 is registered within the European Union as a feed additive complying with Regulation (EC) Number 1831/2003.

Supplier

Meriden Animal Health Limited Cranfield Innovation Centre University Way Cranfield Technology Park Cranfield MK43 0BT Tel: Fax: Email: Web:

+44(0)1234 436130 +44(0)1234 436131 sales@meriden-ah.com www.orego-stim.com www.meriden-ah.com

OREGO-STIM速 is a registered trade mark of Meriden Animal Health Limited.

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OREGO-STIM® Aquatract Liquid new Presentation

A straw coloured liquid containing 20% oregano essential oil as active substance.

Uses

OREGO-STIM® is an animal feed additive with a distinctive aroma that serves as a feed flavour, appetite enhancer, can assist in times of stress and has other interesting properties.

Usage/administration

Apply a liquid coating on pellets post-extrusion. Inclusion rates vary according to conditions. For specific advice contact your nutritionist, veterinarian, distributor or Meriden technical staff. The following rates are given as a guide: SHRIMP 250-500ml liquid per tonne of extruded feed. FIN FISH 125-250ml liquid per tonne of extruded feed.

Compatibility

OREGO-STIM® is 100% natural and therefore compatible with all other types of feed additive.

Contra-indications, warnings, etc.

Do not use in undiluted form.

Pharmaceutical precautions

No withdrawal period necessary. Store in a cool, dry place, out of direct sunlight. Close container securely after use. Shake well before use.

Packaging

12 x 1 litre bottles packed in a heavy-duty box.

Origin

Produced in the United Kingdom in FEMAS certificated production facilities.

Legislation

The active components within OREGO-STIM® are classified by the USFDA as GRAS (Generally Recognised As Safe) substances. OREGO-STIM® is registered within the European Union as a feed additive complying with Regulation (EC) Number 1831/2003.

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Supplier

Meriden Animal Health Limited Cranfield Innovation Centre University Way Cranfield Technology Park Cranfield MK43 0BT Tel: Fax: Email: Web:

+44(0)1234 436130 +44(0)1234 436131 sales@meriden-ah.com www.orego-stim.com www.meriden-ah.com

OREGO-STIM速 is a registered trade mark of Meriden Animal Health Limited

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OREGO-STIM® Aquatract Powder new Presentation

A cream-coloured, free-flowing fine powder containing 5% oregano essential oil as active substance.

Uses

OREGO-STIM® is an animal feed additive with a distinctive aroma that serves as a feed flavour, appetite enhancer, can assist in times of stress and has other interesting properties.

Usage/administration

OREGO-STIM® Aquatract Powder is to be used on the farm. It should be used as a top dressing on feed pellets prior to feeding, using fish oil as an adhesive medium. Inclusion rates vary according to conditions. For specific advice contact your nutritionist, veterinarian, distributor or Meriden technical staff. The following rates are given as a guide: SHRIMP 1000-2000g powder per tonne of feed pellets. FIN FISH 500-1000g powder per tonne of feed pellets.

Compatibility

OREGO-STIM® is 100% natural and therefore compatible with all other types of feed additive.

Contra-indications, warnings, etc.

Do not use in undiluted form.

Pharmaceutical precautions

No withdrawal period is necessary. Store in a cool, dry place, out of direct sunlight. Close container securely after use. Shake well before use.

Packaging

5 x 2.5kg high quality foil bags packed in a heavy duty box.

Origin

Produced in the United Kingdom in FEMAS certificated production facilities.

Legislation

The active components within OREGO-STIM® are classified by the USFDA as GRAS (Generally Recognised As Safe) substances. OREGO-STIM® is registered within the European Union as a feed additive complying with Regulation (EC) Number 1831/2003.

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Supplier

Meriden Animal Health Limited Cranfield Innovation Centre University Way Cranfield Technology Park Cranfield MK43 0BT Tel: Fax: Email: Web:

+44(0)1234 436130 +44(0)1234 436131 sales@meriden-ah.com www.orego-stim.com www.meriden-ah.com

OREGO-STIM速 is a registered trade mark of Meriden Animal Health Limited.

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OTMax™ -Zn, -Cu, -Mn, -Fe new Presentation

OTMax™ is a product range of organic trace minerals, containing chelates of trace minerals bound to hydrolysed amino acids derived from soya.

Product information

Specification EU chelate definition (EC No 1334/2003) TM (x)1-3 . nH2O (x = anion of any amino acid derived from hydrolysed soya protein). Molecular weight not exceeding 1500 Da.

Composition Trace Minerals: 10% (guaranteed minimum) Crude Protein: 30% (guaranteed minimum) of which 20% (minimum) has Dalton weight < 1000 Da. Uses Organic trace minerals have a higher bio-availability than their inorganic equivalents and thereby better support the animal’s requirements for trace minerals. Especially used in cases of disease, stress, high production levels, antagonism in the diet or low maximum mineral inclusion levels allowed by legislation. Dosage/administration

Varies according to animal species and application.

Legal category

EC No 1334/2003

Trace element chelates of amino acid hydrate

Zn (E6), Cu (E4), Mn (E5), Fe (E1)

Further information

Shelf life 2 years from production date.

Package quantities

25kg paper bags (Zn, Mn and Fe); 15kg paper bags (Cu).

Supplier

Orffa Additives BV Vierlinghstraat 51 4251 LC Werkendam The Netherlands

Orffa UK Office PO Box 113 Northallerton North Yorkshire DL6 1YH

Tel: +31 (0) 183 44 77 44 Fax: +31 (0) 183 44 30 60 E-mail: info@orffa.com Website: www.orffa.com

Tel: +44 (0) 1609 772881 Fax: +44 (0) 1609 780941

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pHorce Presentation

new

pHorce is a white synergistic blend of organic acids, on a silica micro pearl carrier, for use as an acidifier in pig and poultry feed. Colour: Odour: pH:

white acid 3.5

Use

pHorce is a synergistic blend of the most potent short-chain fatty acids. It has been shown to have excellent acidifying properties and the ability to help establish a beneficial gut microflora.

Dosage/administration

The recommended inclusion rate for pHorce is:

Finished Feed

0.75-1.00kg/tonne

Raw Materials

2.00-4.00kg/tonne

Package sizes

25kg poly-lined paper bags.

Further information

For animal use only.

No withdrawal period is required.

Legal category

The components of pHorce are fully approved by the EC as preservatives for use in animal feeds.

Supplier

Kiotechagil Hercules 2 Calleva Park Reading Berkshire RG7 8DN Tel: Fax: E-Mail: Website:

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0118 981 3333 0118 981 0909 info@kiotechagil.com www.kiotechagil.com

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Phyzyme® XP 5000G Presentation

Phyzyme® XP 5000G is supplied as a light brown, fine granular product. Bulk weight: 650kg/m³. Moisture content: Maximum 12%.

Use

Phyzyme XP is a phytase feed enzyme specifically developed to increase the digestability of phytin-bound phosphorus, calcium, energy and amino acids in poultry and pig diets.

Dosage/administration

Broilers: Use at a rate of 0.05-0.15kg/tonne of complete feed rich in phytates as recommended by the Phycheck™dose optimisation service.

Laying hens: Use at a rate of 0.03-0.18kg/tonne of complete feed rich in phytates as recommended by the Phycheck™dose optimisation service.

Turkeys: Use at a rate of 0.05-0.2kg/tonne of complete feed rich in phytates as recommended by the Phycheck™dose optimisation service.

Ducks: Use at a rate of 0.05-0.2kg/tonne of complete feed rich in phytates as recommended by the Phycheck™dose optimisation service.

Piglets: Use at a rate of 0.05-0.2kg/tonne of complete feed rich in phytates as recommended by the Phycheck™dose optimisation service. Growing/finishing pigs: Use at a rate of 0.05-0.2kg/tonne of complete feed rich in phytates as recommended by the Phycheck™dose optimisation service. Sows: Use at a rate of 0.1kg/tonne of complete feed rich in phytates. Use and Dosage/Administration is subject to individual registration. For specific details contact supplier.

Package sizes

25kg multi-wall paper bags and in 1000kg bulk (tote) bags.

Further information

Guaranteed minimum activity: 5000 FTU/g 6-phytase (IUB No. EC 3.1.3.26). Analysis methods detailing assay conditions are available upon request.

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Stability and storage: For optimum bioefficacy, do not exceed conditioning and pelleting temperatures of 70°C. Phyzyme XP 5000G is stable for 12 months when stored in original packaging at ≤ 20°C and for 4 months when included in a vitamin/mineral premix. Store in dry conditions. Safety and purity: Available on request. There are no producing micro-organisms in the final product. None of the ingredients is of animal origin. Handling: Provide for good ventilation and avoid dust formation. It is recommended to use protective glasses, respiratory mask and gloves during handling. In case of accidental contact with skin or eyes, the only action needed is copious flushing with water. See the Material Safety Data Sheet for further information. Legal category

Enzyme

Supplier

Danisco Animal Nutrition PO Box 777 Marlborough Wiltshire SN8 1XN Tel: Fax: E-mail: Web:

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01672 517777 01672 517778 info.animalnutrition@danisco.com www.danisco.com/animalnutrition

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Phyzyme® XP 5000L Presentation

Phyzyme® XP 5000L is supplied as a brown liquid. Specific Gravity: Viscosity: Freezing point: pH:

1.05-1.15g/ml 2.5 cPs at 24°C -15°C 4.4-4.8

Use

Phyzyme XP is a liquid phytase feed enzyme specifically developed to increase the digestability of phytin-bound phosphorus, calcium, energy and amino acids in poultry and pig diets.

Dosage/administration

Broilers: Use at a rate of 0.05-0.15kg/tonne of complete feed rich in phytates as recommended by the Phycheck™dose optimisation service. Must apply post-pelleting.

Laying hens: Use at a rate of 0.03-0.18kg/tonne of complete feed rich in phytates as recommended by the Phycheck™dose optimisation service. Must apply post-pelleting.

Turkeys: Use at a rate of 0.05-0.2kg/tonne of complete feed rich in phytates as recommended by the Phycheck™dose optimisation service. Must apply post-pelleting.

Ducks: Use at a rate of 0.05-0.2kg/tonne of complete feed rich in phytates as recommended by the Phycheck™dose optimisation service. Must apply post-pelleting.

Piglets: Use at a rate of 0.05-0.2kg/tonne of complete feed rich in phytates as recommended by the Phycheck™dose optimisation service. Must apply post-pelleting. Growing/finishing pigs: Use at a rate of 0.05-0.2kg/tonne of complete feed rich in phytates as recommended by the Phycheck™dose optimisation service. Must apply postpelleting. Sows: Use at a rate of 0.1kg/tonne of complete feed rich in phytates. Must apply post-pelleting. Use and Dosage/Administration is subject to individual registration. For specific details contact supplier.

Package sizes

Containers of 200kg and 1000kg.

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Further information

Suitable for all processing conditions, particularly where conditioning and pelleting temperatures exceed 70°C.

Guaranteed minimum activity: 5000 FTU/g 6-phytase (IUB No.EC 3.1.3.26). Analysis methods detailing assay conditions are available upon request. Stability and storage: Phyzyme XP 5000L is stable for 9 months when stored in original packaging at ≤ 20°C. Do not freeze. Safety and purity: Available on request. There are no producing micro-organisms in the final product. None of the ingredients is of animal origin. Handling: Provide for good ventilation and avoid aerosol formation. It is recommended to use protective glasses, respiratory mask and gloves during handling. In case of accidental contact with skin or eyes, the only action needed is copious flushing with water. See the Material Safety Data Sheet for further information.

Legal category

Enzyme

Supplier

Danisco Animal Nutrition PO Box 777 Marlborough Wiltshire SN8 1XN Tel: Fax: E-mail: Web:

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01672 517777 01672 517778 info.animalnutrition@danisco.com www.danisco.com/animalnutrition

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PigZin Premix Presentation

A soft, white or faintly yellowish-white amorphous powder comprising 100 per cent zinc oxide PhEur. A premix for incorporation into feedingstuffs.

Uses

For oral administration in the treatment and control of diarrhoea in pigs up to ten weeks of age.

Dosage/administration

To be incorporated in feed at a rate of 3.1kg per tonne of finished feed to supply approximately 2500mg zinc per kg feed. Feed as the only feed for up to 14 days.

Withdrawal period

Animals must not be slaughtered for human consumption during treatment. Pigs may be slaughtered for human consumption only after 28 days after the end of treatment.

Pharmaceutical precautions

Store below 25째C in a clean, dry place. Close the bag securely after use. Store apart from animal feedingstuffs. To ensure thorough dispersion of the product it should first be mixed with ten times its weight of a feed ingredient before incorporation into the final mix. The shelf life following incorporation into feed is three months.

General precautions

Dispose of any unused product and waste medicated feed in accordance with guidance from your local waste regulation authority, eg local regional office of the Environment Agency or SEPA.

Operator warnings

Wear either a disposable half-mask respirator conforming to European Standard EN149 or a non-disposable respirator to European Standard EN140 with a filter to EN143 when mixing or handling the feed. Avoid contact with eyes by wearing protective goggles or safety glasses. In case of accidental eye contact, irrigate thoroughly with large quantities of water. Avoid contact with skin by wearing protective clothing including impermeable gloves. Contaminated clothing should be removed and washed before being reused. In case of accidental skin contact, wash the exposed skin with soap and water.

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In case of accidental ingestion, drink plenty of water and seek medical attention. Wash hands after use. Keep out of the reach of children. For animal treatment only. Legal category

POM-V

Package quantities

Available in 25kg multi-walled paper sacks conforming to new UN approved standards.

Marketing authorisation number

MA Vm 19108/4000

Marketing authorisation holder

DSM Nutritional Products (UK) Ltd Heanor Gate Heanor Derbyshire DE75 7SG

Tel: Fax: Website:

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01773 536500 01773 536600 www.dsmnutritionalproducts.com

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Porzyme® 8300 Presentation

Porzyme 8300 is supplied as a light brown, fine granular product. Bulk weight: 650kg/m3 Moisture content: Maximum 12%

Uses

Porzyme 8300 is a feed enzyme system specifically developed to improve the nutritional value of wheat-based piglet diets.

Dosage/administration

Use at a rate of 1kg/tonne of complete feed. Use and Dosage/administration is subject to individual registration. For specific details contact supplier.

Package sizes

25kg multi-wall paper sacks and 1000kg bulk (tote) bags.

Further information

Guaranteed minimum activity: 5000 units xylanase/g (IUB No. EC 3.2.1.8) and 500 units protease/g (IUB No. EC 3.4.21.62). Analysis methods detailing assay conditions are available upon request. Stability and storage: For optimum bioefficacy, do not exceed conditioning and pelleting temperatures of 85°C. Porzyme 8300 is stable for 12 months when stored in original packaging at ≤ 22°C and for 3 months when included in a vitamin/mineral premix. Store in dry conditions. Safety and purity: Available upon request. There are no producing micro-organisms in the final product. None of the ingredients is of animal origin. Handling: Provide for good ventilation and avoid dust formation. It is recommended to use protective glasses, respiratory mask and gloves during handling. In case of accidental contact with skin or eyes, the only action needed is copious flushing with water. See the Material Safety Data Sheet for further information.

Legal category

Enzyme

Supplier

Danisco Animal Nutrition PO Box 777 Marlborough Wiltshire SN8 1XN Tel: Fax: E-mail: Web:

01672 517777 01672 517778 info.animalnutrition@danisco.com www.danisco.com/animalnutrition

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Porzyme® 9100 Presentation

Porzyme 9100 is supplied as a light brown, fine granular product. Bulk weight: 650kg/m3 Moisture content: Maximum 12%

Uses

Porzyme 9100 is a feed enzyme system specifically developed to improve the nutritional value of barley-based pig diets.

Dosage/administration

Growing/finishing pigs: Use at a rate of 1.0kg/tonne of complete feed.

Piglets: Use at a rate of 0.5-1.0kg/tonne of complete feed. Use and Dosage/administration is subject to individual registration. For specific details contact supplier.

Package sizes

25kg multi-wall paper sacks and 1000kg bulk (tote) bags.

Further information

Guaranteed minimum activity: 400 units β-glucanase/g (IUB No. EC 3.2.1.6). 400 units xylanase/g (IUB No. EC 3.2.1.8). An analysis method detailing assay conditions is available upon request. Stability and storage: For optimum bioefficacy, do not exceed conditioning and pelleting temperatures of 85°C. Porzyme 9100 is stable for 12 months when stored in original packaging at ≤ 22°C and for 3 months when included in a vitamin/mineral premix. Store in dry conditions. Safety and purity: Available on request. There are no producing micro-organisms in the final product. None of the ingredients is of animal origin. Handling: Provide for good ventilation and avoid dust formation. It is recommended to use protective glasses, respiratory mask and gloves during handling. In case of accidental contact with skin or eyes, the only action needed is copious flushing with water. See the Material Safety Data Sheet for further information.

Legal category

Enzyme

Supplier

Danisco Animal Nutrition PO Box 777 Marlborough Wiltshire SN8 1XN Tel: 01672 517777 Fax: 01672 517778 E-mail: info.animalnutrition@danisco.com Web: www.danisco.com/animalnutrition

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Porzyme® 9302 Presentation

Porzyme 9302 is supplied as a light brown, fine granular product. Bulk weight: 650kg/m3 Moisture content: Maximum 12%

Uses

Porzyme 9302 is a feed enzyme system specifically developed to improve the nutritional value of wheat-based diets.

Dosage/administration

Piglets: Use at a rate of 0.5kg/tonne of complete feed. Growing/finishing pigs: Use at a rate of 0.125-0.5kg/tonne of complete feed. Broilers: Use at a rate of 0.0625-0.3125kg/tonne of complete feed. Based on Avizyme® 1310. Use and Dosage/administration is subject to individual registration. For specific details contact supplier.

Package sizes

25kg multi-wall paper sacks and 1000kg bulk (tote) bags.

Further information

Guaranteed minimum activity: 8000 units xylanase/g (IUB No. EC 3.2.1.8). An analysis method detailing assay conditions is available upon request. Stability and storage: For optimum bioefficacy, do not exceed conditioning and pelleting temperatures of 85°C. Porzyme 9302 is stable for 12 months when stored in original packaging at ≤ 22°C and for 3 months when included in a vitamin/mineral premix. Store in dry conditions. Safety and purity: Available on request. There are no producing micro-organisms in the final product. None of the ingredients is of animal origin. Handling: Provide for good ventilation and avoid dust formation. It is recommended to use protective glasses, respiratory mask and gloves during handling. In case of accidental contact with skin or eyes, the only action needed is copious flushing with water. See the Material Safety Data Sheet for further information.

Legal category

Enzyme

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Supplier

Danisco Animal Nutrition PO Box 777 Marlborough Wiltshire SN8 1XN Tel: Fax: E-mail: Web:

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Porzyme® 9310 Presentation

Porzyme 9310 is supplied as a yellow to brown liquid. Specific gravity: 1.1g/ml Viscosity: 3.0 cPs at 24°C pH: 4.5-5.0

Uses

Porzyme 9310 is a liquid feed enzyme system specifically developed to improve the nutritional value of wheat-based diets.

Dosage/administration

Piglets: Use at a rate of 0.5kg/tonne of complete feed. Must apply post-pelleting. Growing/finishing pigs: Use at a rate of 0.125-0.5kg/tonne of complete feed. Must apply post-pelleting. Broilers: Use at a rate of 0.0625-0.3125kg/tonne of complete feed. Based on Avizyme® 1310. Must apply post-pelleting. Use and Dosage/administration is subject to individual registration. For specific details contact supplier.

Package sizes

Containers of 25kg, 200kg and 1000kg.

Further information

Guaranteed minimum activity: 8000 units xylanase/g (IUB No. EC 3.2.1.8). An analysis method detailing assay conditions is available upon request. Stability and storage: For any processing conditions, particularly where conditioning and pelleting temperatures exceed 85°C. Porzyme 9310 is stable for 6 months when stored in original packaging at ≤ 22°C. Do not freeze. Safety and purity: Available on request. There are no producing micro-organisms in the final product. None of the ingredients is of animal origin. Handling: Provide for good ventilation and avoid aerosol formation. It is recommended to use protective glasses, respiratory mask and gloves during handling. In case of accidental contact with skin or eyes, the only action needed is copious flushing with water. See the Material Safety Data Sheet for further information.

Legal category

Enzyme

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Supplier

Danisco Animal Nutrition PO Box 777 Marlborough Wiltshire SN8 1XN Tel: Fax: E-mail: Web:

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Keep this Handbook up-to-date! When this Handbook was published, in February 2009, everything possible had been done by the publisher and product suppliers to ensure the information contained was accurate and up-to-date. Inevitably, some products will be subject to important changes between publication of this edition and the next. Whenever we are notified of changes to product information contained in this edition, these changes will be posted on our website at: www.simonmounsey.com/hbupdate.htm The updates will be in the form of replacement pages which can be printed out and used to replace pages in the original. As an additional service to users of this book, you may register to receive notification whenever an updated page is posted. Simply send an email to mail@simonmounsey.com with the subject line â&#x20AC;&#x153;Handbook Updates 2009â&#x20AC;? and your email address for notification.

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Potencil Presentation

A grey free-flowing powder for incorporation into animal feed, containing 10% Phenoxymethyl penicillin potassium PhEur (100g/ kg).

Uses

For the treatment and control of streptococcal meningitis and septicaemia in pigs. Also for the treatment and control of porcine pleuropneumonia caused by Actinobacillus pleuropneumoniae and treatment and control of secondary bacterial pneumonia caused by Pasteurella multocida.

Dosage/administration

For oral administration after incorporation in pelleted feed or meal at an inclusion level of 2kg Potencil per tonne of feed. To be fed ad libitum for up to six consecutive weeks for meningitis/ septicaemia and up to two weeks for pleuropneumonia/ pneumonic pasteurellosis. Freshly manufactured medicated diet should be supplied at intervals of a fortnight. After inclusion of Potencil, feed must be used before the end of a fourteen day period from manufacture, due to loss of potency of the active ingredient.

Contra-indications, warnings, etc.

Animals must not be slaughtered for human consumption during treatment. Pigs may be slaughtered for human consumption only after 24 hours from the last treatment. Not for direct feeding. Not for use in liquid feed.

Not for use in animals known to be hypersensitive to penicillins.

Studies to determine the safety of this product for use during pregnancy have not been conducted in pigs. Use in pregnant pigs should be in accordance with a benefit/risk assessment by the responsible veterinarian.

Operator warnings

Pencillins and cephalosphorins may cause hypersensitivity (allergy) following injection, inhalation, ingestion or skin contact. Hypersensitivity to penicillin may lead to cross sensitivity to cephalosporins and vice-versa. Allergic reactions to those substances are occasionally serious. Do not handle this product if you know you are sensitised or if you have been advised not to work with such preparations.

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Handle this product with great care to avoid exposure taking all recommended precautions. Wear protective clothing, gloves and a dust mask, either a disposable half-mask respirator conforming to European standard EN149 or a non-disposable respirator to European standard EN140 with a filter to EN143, when preparing medicated feed. If you develop symptoms following exposure such as skin rash you should seek medical advice and show the doctor this warning. Swelling of the face, lips or eyes or difficulty in breathing are more serious symptoms and require urgent medical attention. Wash hands after use. Disposal advice

Unused product and/or containers should be disposed of in accordance with advice from an appropriate waste regulation authority.

Pharmaceutical precautions

To allow thorough dispersion of the product, Potencil should be mixed with a small quantity of feed prior to mixing into the bulk of the feed. In pelleting, the mix can be pre-conditioned with steam for up to five minutes and processed at temperatures in the feed of up to 70째C. After incorporation under these conditions Potencil retains satisfactory activity for two weeks. Do not store above 25째C. Store in a dry place. Close container after use. Fourteen days after incorporation of 2kg Potencil per tonne of feed (200mg/kg of Phenoxymethyl penicillin potassium) the level of Phenoxymethyl penicillin potassium has shown to be approximately 60mg/kg. Clinical trials have demonstrated the efficacy of Potencil in these circumstances. Feed containing Potencil must be used within 14 days due to the known instability of Potencil. Keep out of reach of children. For animal treatment only. Use only under veterinary direction. Accurate mixing is essential.

Further information

On commercial pig farms Potencil has been shown to be very effective in the control and treatment of streptoccocal meningitis/ septicaemia and control of Actinobacillus pleuropneumoniae and Pasteurella multocida infections.

Legal category

POM-V

Package quantities

2kg, 6kg polyethylene paper bag. 25kg multi-walled polyethylenelined paper sacks.

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Marketing authorisation number

Vm 12501/4116.

Marketing authorisation holder

Novartis Animal Health UK Ltd

Marketed and distributed by

Novartis Animal Health UK Ltd Frimley Business Park Frimley Camberley Surrey GU16 7SR

Tel: 01276 694402

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Pulmotil® G100 Premix Presentation

Pulmotil G100 Premix is a yellowish tan to reddish tan free‑flowing granular material for inclusion in animal feeding stuffs. Each 1kg of Pulmotil G100 Premix contains tilmicosin, as the phosphate, equivalent to 100g tilmicosin activity.

Uses

For the treatment of pneumonia in growing fattening pigs, caused by Actinobacillus pleuropneumoniae, Mycoplasma hyopneumoniae, Haemophilus parasuis, Pasteurella multocida and other organisms sensitive to tilmicosin.

Dosage/administration

The product should be thoroughly mixed into the complete feed. For the treatment of outbreaks of pneumonia in growing fattening pigs, use 200-400g tilmicosin activity per tonne of feed for 15 days. This provides a dose rate of 8-16mg/kg bodyweight and is achieved by the incorporation of 2-4kg Pulmotil G100 Premix per tonne of feed.

Contra‑indications, warnings, etc.

For animal treatment only. For use in pig feed only. The safety of tilmicosin has not been established in boars used for breeding purposes. Do not allow horses or other equines access to feeds containing tilmicosin. KEEP OUT OF THE REACH OF CHILDREN. Operator warnings: May cause sensitisation by skin contact. May cause skin irritation. Avoid direct skin contact. Wear overalls and impervious gloves when mixing and handling the product. Wash affected parts if skin contact occurs. If accidental eye contact occurs, immediately rinse thoroughly with water. If the operations involve the risk of exposure to dust, wear either a disposable filter and half mask respirator conforming to European Standard EN149 or a non‑disposable respirator to European Standard EN140 fitted with a filter to EN143. This warning is particularly relevant to on‑farm mixing, where the risk of exposure to dust is likely to be enhanced. Withdrawal Period: 14 days. Slurry from treated animals should not be deposited on the same field in successive years.

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Pharmaceutical precautions

To ensure thorough dispersion of the product it should first be mixed with a suitable quantity of feed ingredients before incorporating in the final mix. Do not incorporate into feeds containing Bentonite. The product will remain stable in the finished feed for one month. This is also applicable when feed is manufactured using pre‑conditioning temperatures of up to 75°C over the minimum time period. Store in a dry place, below 25°C, protect from direct sunlight.

Legal category

POM-V

Package quantities

Pulmotil G100 Premix is supplied in either hermetically sealed polyethylene/polyamide laminated sacks containing 10kg of product, or multiwall kraft paper sacks including a polyethylene layer, each sack containing 2kg or 10kg of product.

Further information

None

Marketing authorisation number

Vm 00006/4095

Marketing authorisation holder

Elanco Animal Health Lilly House Priestley Road Basingstoke Hampshire RG24 9NL

Tel: Fax:

®Pulmotil is a registered trademark of Eli Lilly and Company Ltd.

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(01256) 353131 (01256) 779510

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Pulmotil® G200 Premix Presentation

Pulmotil G200 Premix is a yellowish tan to reddish tan free‑flowing granular material for inclusion in animal feeding stuffs. Each 1kg of Pulmotil G200 Premix contains tilmicosin, as the phosphate, equivalent to 200g tilmicosin activity.

Uses

For the treatment of pneumonia in growing fattening pigs, caused by Actinobacillus pleuropneumoniae, Mycoplasma hyopneumoniae, Haemophilus parasuis, Pasteurella multocida and other organisms sensitive to tilmicosin.

Dosage/administration

The product should be thoroughly mixed into the complete feed. For the treatment of pneumonia in growing fattening pigs, use 200-400g tilmicosin activity per tonne of feed for 15 days. This provides a dose rate of 8-16mg/kg bodyweight and is achieved by the incorporation of 1-2kg of Pulmotil G200 Premix per tonne of feed.

Contra‑indications, warnings, etc.

For animal treatment only. For use in pig feed only. Do not allow horses or other equines access to feeds containing tilmicosin. KEEP OUT OF THE REACH OF CHILDREN. Operator warnings: May cause sensitisation by skin contact. May cause skin irritation. Avoid direct skin contact. Wear overalls and impervious gloves when mixing and handling the product. Wash affected parts if skin contact occurs. If accidental eye contact occurs, immediately rinse thoroughly with water. If the operations involve the risk of exposure to dust, wear either a disposable filter and half mask respirator conforming to European Standard EN149 or a non‑disposable respirator to European Standard EN140 fitted with a filter to EN143. This warning is particularly relevant to on‑farm mixing, where the risk of exposure to dust is likely to be enhanced. Withdrawal Period: 14 days. Slurry from treated animals should not be deposited on the same field in successive years.

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Pharmaceutical precautions

To ensure thorough dispersion of the product it should first be mixed with a suitable quantity of feed ingredients before incorporating in the final mix. Do not incorporate into feeds containing Bentonite. The product will remain stable in the finished feed for one month. This is also applicable when feed is manufactured using pre‑conditioning temperatures of up to 75°C over the minimum time period. Store in a dry place, below 25°C, protect from direct sunlight.

Legal category

POM-V

Package quantities

Pulmotil G200 Premix is supplied in hermetically sealed polyethylene/polyamide laminated sacks containing 10kg of product.

Further information

None

Marketing authorisation number

Vm 00006/4096

Marketing authorisation holder

Elanco Animal Health Lilly House Priestley Road Basingstoke Hampshire RG24 9NL

Tel: Fax:

®Pulmotil is a registered trademark of Eli Lilly and Company Ltd.

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Quantum™ Phytase

new

Presentation

Quantum™ Phytase is an enzyme preparation developed to increase the digestibility of phytin-bound phosphorus and other dietary nutrients. Supplied as powder or liquid product.

Use

Specifically developed for use in poultry and pig diets containing phytin-bound phosphorus.

Dosage/administration

For use in broiler, duck, turkey and piglet diets:

Broilers:

from 200g/tonne of powder product from 100g/tonne of liquid product

Ducks:

from 100g/tonne of powder product from 50g/tonne of liquid product

Turkeys:

from 400g/tonne of powder product from 200g/tonne of liquid product

Piglets:

from 40g/tonne of powder product from 20g/tonne of liquid product

Package sizes

Quantum™ Phytase 2500 XT (powder): 25kg Quantum™ Phytase 5000 L (liquid): 120kg and 1000kg

Further information

Guaranteed minimum activity 2500 FTU/g in Quantum™ Phytase 2500 XT (powder) 5000 FTU/g in Quantum™ Phytase 5000 L (liquid)

Stability and storage Quantum™ Phytase 2500 XT: 12 months when stored at 21°C. Quantum™ Phytase 5000 L: 12 months when stored at 10°C.

Thermostability It is recommended to use Quantum™ Phytase 5000 L when the conditioning and pelleting temperature exceeds 85°C.

EU authorisation

4a5

Supplier

AB Vista™ 3 Woodstock Court Blenheim Road Marlborough Business Park Marlborough Wiltshire SN8 4AN United Kingdom

Telephone: Fax: Email: Website:

+44 (0)1672 517650 +44 (0)1672 517660 info@ab-vista.com www.ab-vista.com

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RONOZYME® A (CT) Presentation

RONOZYME A (CT) is a stabilised, light brown, coated, non-dusty granulate containing a mixture of alpha-amylase (EC/IUB No. 3.2.1.1 – minimum activity 200 KNU/g) and endo-1,3(4)-βglucanase (EC/IUB No. 3.2.1.6 – minimum activity 350 FBG/g) derived from Bacillus amyloliquefaciens. The bulk density is approximately 1.0g/ml and the average particle size is approx. 600µm.

Uses

RONOZYME A (CT) has been demonstrated to be effective in improving the utilisation of feeds which are rich in non-starch polysaccharides (NSPs) (mainly β-glucans).

Dosage/administration

50-200g per tonne of feed, depending on feed formulation.

Contra-indications/ precautions

For animal use only. The product is safe for the intended use. Avoid ingestion, inhalation of dust or direct contact by applying suitable protective measures and personal hygiene. For full safety information and necessary precautions, please refer to the respective DSM Product Specification and Safety Data Sheets.

Additive functional group

Digestibility enhancer.

Packaging quantities

20kg multi-walled paper sacks with plastic in-liner.

Further information

RONOZYME A (CT) maintains its declared activity for at least 24 months from the date of manufacture when the product is stored in the unopened original container and at a temperature below 25°C. Prolonged storage at temperatures above 30°C should be avoided. The effective best used before date is printed on the label.

EU authorisation

RONOZYME A (CT) is permanently approved as E1619 for chickens for fattening.

Supplier

DSM Nutritional Products (UK) Ltd Heanor Gate Heanor Derbyshire DE75 7SG

Tel: Fax: Website:

RONOZYME® is a registered trademark.

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RONOZYME® P5000 (CT) Presentation

RONOZYME P5000 (CT) is a stabilised, beige, coated, non-dusty granulate phytase preparation derived from Peniophora lycii. It contains phytase (EC/IUB No. 3.1.3.26 – minimum activity 5000 FYT/g). The average particle size is approx. 460µm.

Uses

RONOZYME P5000 (CT) has been demonstrated to be effective in improving the utilisation of feeds which contain phytate phosphorus.

Dosage/administration

Typically recommended usage levels are: Broilers: Turkeys: Ducks: Laying hens: Piglets/pigs/sows:

Contra-indications/ precautions

150g/tonne 150g/tonne 150g/tonne 90g/tonne 150g/tonne

For animal use only. The product is safe for the intended use. Avoid ingestion, inhalation of dust or direct contact by applying suitable protective measures and personal hygiene. For full safety information and necessary precautions, please refer to the respective DSM Product Specification and Safety Data Sheets.

Additive functional group

Digestibility enhancer.

Packaging quantities

20kg multi-walled paper sacks with plastic in-liner.

Further information

RONOZYME P5000 (CT) maintains its declared activity for at least 12 months from the date of manufacture when stored in the unopened original container and at a temperature below 25°C. Prolonged storage at temperatures above 30°C should be avoided. The effective best used before date is printed on the label.

EU authorisation

RONOZYME P5000 (CT) is permanently approved as E1614(i) for chickens for fattening, turkeys for fattening, laying hens, ducks, piglets, pigs for fattening and sows.

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Supplier

DSM Nutritional Products (UK) Ltd Heanor Gate Heanor Derbyshire DE75 7SG

Tel: Fax: Website:

RONOZYME速 is a registered trademark.

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Handbook of Feed Additives 2009 Handbook of Feed Additives 2009 is one of several directories, periodicals and reports published by Simon Mounsey Ltd. Amongst our other titles for feed producers and their suppliers are: • Feed Statistics 2009 • Feed Businesses 2009 • Feed Industry Review Details about these and other publications and services can be found on our website at: www.simonmounsey.com

Updates to this Handbook can also be found on the same website. You can go directly to the updates site at the following address: www.simonmounsey.com/hbupdate.htm

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RONOZYME® VP (CT) Presentation

RONOZYME VP (CT) is a stabilised, light brown, coated, non-dusty granulate carbohydrase preparation derived from Aspergillus aculeatus. It contains endo-1,3(4)-β-glucanase (EC/IUB No. 3.2.1.6 – minimum activity 50 FBG/g), pentosanase, hemicellulase and pectinase. The bulk density is approximately 1.1g/ml and the average particle size is approx. 500-600µm.

Uses

RONOZYME VP (CT) has been demonstrated to be effective in improving the utilisation of feeds which are rich in hemicelluloses derived from cereals and vegetable proteins.

Dosage/administration

Recommended usage levels is:

200-500g per tonne of feed, depending on the type of feed.

Contra-indications/ precautions

For animal use only. The product is safe for the intended use. Avoid ingestion, inhalation of dust or direct contact by applying suitable protective measures and personal hygiene. For full safety information and necessary precautions, please refer to the respective DSM Product Specification and Safety Data Sheets.

Additive functional group

Digestibility enhancer.

Packaging quantities

20kg multi-walled paper sacks with plastic in-liner.

Further information

RONOZYME VP (CT) maintains its declared activity for at least 12 months from the date of manufacture when the product is stored in the unopened original container and at a temperature below 25°C. Prolonged storage at temperatures above 30°C should be avoided. The effective best used before date is printed on the label.

EU authorisation

RONOZYME VP (CT) is permanently approved as E1603 for chickens for fattening and piglets (to approximately 35kg).

Supplier

DSM Nutritional Products (UK) Ltd Heanor Gate Heanor Derbyshire DE75 7SG

Tel: Fax: Website:

RONOZYME® is a registered trademark.

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RONOZYME® WX (CT) Presentation

RONOZYME WX (CT) is a stabilised, light brown, coated, nondusty granulate containing a heat-stable endo-xylanase derived from Thermomyces lanuginosus. The main activity is endo-1,4-βxylanase (EC/IUB No. 3.2.1.8 – minimum activity 1000 FXU/g). The bulk density is approximately 1.1g/ml and the average particle size is approx. 600µm.

Uses

RONOZYME WX (CT) has been demonstrated to be effective in improving the utilisation of feeds which are rich in non-starch polysaccharides (NSPs)(mainly arabinoxylans).

Dosage/administration

Recommended usage levels are: Broilers: Turkeys: Ducks: Piglets: Pigs

Contra-indications/ precautions

150-200g/tonne 150-200g/tonne 150-200g/tonne 200-300g/tonne 200g/tonne

For animal use only. The product is safe for the intended use. Avoid ingestion, inhalation of dust or direct contact by applying suitable protective measures and personal hygiene. For full safety information and necessary precautions, please refer to the respective DSM Product Specification and Safety Data Sheets.

Additive functional group

Digestibility enhancer.

Packaging quantities

20kg multi-walled paper sacks with plastic in-liner.

Further information

RONOZYME WX (CT) maintains its declared activity for at least 12 months from the date of manufacture at a temperature below 25°C and for at least 24 months from the date of manufacture at a temperature below 5°C when stored in the unopened original container. Prolonged storage at temperatures above 30°C should be avoided. The effective best used before date is printed on the label.

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EU authorisation

RONOZYME速WX (CT) is permanently approved as E1607 for chickens for fattening, turkeys for fattening and piglets (to approximately 35kg) and provisionally approved for ducks and pigs for fattening.

Supplier

DSM Nutritional Products (UK) Ltd Heanor Gate Heanor Derbyshire DE75 7SG

Tel: Fax: Website:

RONOZYME速 is a registered trademark.

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Rovabio® Excel AP Presentation

Rovabio® Excel AP is a light to dark beige concentrated powder whose main enzymatic activities are β-xylanase and β-glucanase obtained from a fermentation broth of Penicillium funiculosum. The main active substances are endo-1,4-β-xylanase (EC No. 3.2.1.8 – minimum activity 1,400 AXC units/g) and endo-1,3(4)-βglucanase (EC No. 3.2.1.6 – minimum activity 2000 AGL units/g). There are a further 19 enzyme activities, including cellulase (endo-1,4-β-glucanase). Density: Particle size:

400-600kg/m3 Above 500µm – No more than 10% 100-500µm – 85-90%

Use

Rovabio® Excel AP may be incorporated into animal feed. It can be used in either meal or pellets produced at temperatures below 85°C to hydrolyse pentosans and β-glucans in vegetable raw materials.

The effect of this activity is to:

• Improve the nutritional value of feeds containing different types of cereals (wheat, maize, barley, triticale, rye, oats, etc) and oilseed meals (soybean, sunflower, canola, etc).

• Reduce gut viscosity. • Reduce the free ammonia concentration in the litter. Dosage/administration

Dose: Use at a rate of 50g Rovabio® Excel AP/tonne of feed.

This dose rate is equivalent to: xylanase – 70 AXC units/kg feed. β-glucanase – 100 AGL units/kg feed.

Administration: This product should be diluted in a premix before incorporation in feeds.

It is recommended to check enzyme activity in feeds using the Rovabio® Test Kit.

Package sizes

25kg cardbox (500kg per pallet).

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Further information

Methods of analysis: Details of the methods for analysing activity and assay methods are available upon request. Storage: Rovabio® Excel AP is stable for 12 months from the manufacturing date when stored in closed packaging below 30°C. Store in dry conditions. Safety: A safety data sheet for Rovabio® Excel AP is available on request. There are no active micro-organisms in the final product. Safety in feed: Once incorporated into the feed, the product offers all original guarantees of safety. Handling: Handling the product may cause allergic reactions by inhalation.

◊ EU authorisation

Rovabio® Excel AP is approved as E1604 for broilers, layers, turkeys, ducks, pigs and piglets.

Supplier

Adisseo Berkhamsted House 121 High Street Berkhamsted Hertfordshire HP4 2DJ Tel: Fax: E-mail: Web:

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Rovabio® Excel AP T-Flex new Presentation

Rovabio® Excel AP T-Flex is a light to dark beige concentrated powder whose main enzymatic activities are β-xylanase and β-glucanase obtained from a fermentation broth of Penicillium funiculosum. The main active substances are endo-1,4-β-xylanase (EC No. 3.2.1.8 – minimum activity 1,400 AXC units/g) and endo-1,3(4)-βglucanase (EC No. 3.2.1.6 – minimum activity 2000 AGL units/g). There are a further 19 enzyme activities, including cellulase (endo-1,4-β-glucanase). Density: Particle size:

400-600kg/m3 Above 500µm – No more than 10% 100-500µm – 85-90%

Use

Rovabio® Excel AP T-Flex may be incorporated into animal feed meal or pellets. It has a unique protective coating so it can be used at pelleting temperatures up to 90°C.

The effect of Rovabio® Excel AP T-Flex is to:

• Improve the nutritional value of feeds containing different types of cereals (wheat, maize, barley, triticale, rye, oats, etc) and oilseed meals (soybean, sunflower, canola, etc).

• Reduce gut viscosity. • Reduce the free ammonia concentration in the litter. Dosage/administration

Dose: Use at a rate of 50g Rovabio® Excel AP T-Flex/tonne of feed.

This dose rate is equivalent to: xylanase – 70 AXC units/kg feed. β-glucanase – 100 AGL units/kg feed.

Administration: This product should be diluted in a premix before incorporation in feeds.

It is recommended to check enzyme activity in feeds using the Rovabio® Test Kit.

Package sizes

25kg cardbox (500kg per pallet).

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Further information

Methods of analysis: Details of the methods for analysing activity and assay methods are available upon request. Storage: Rovabio速 Excel AP T-Flex is stable for 12 months from the manufacturing date when stored in closed packaging below 30属C. Store in dry conditions. Safety: A safety data sheet for Rovabio速 Excel AP T-Flex is available on request. There are no active micro-organisms in the final product. Safety in feed: Once incorporated into the feed, the product offers all original guarantees of safety. Handling: Handling the product may cause allergic reactions by inhalation.

EU authorisation

Rovabio速 Excel AP T-Flex is approved as E1604 for broilers, layers, turkeys, ducks, pigs and piglets.

Supplier

Adisseo Berkhamsted House 121 High Street Berkhamsted Hertfordshire HP4 2DJ Tel: Fax: E-mail: Web:

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Rovabio® Excel LC Presentation

Rovabio® Excel LC is a clear to brown concentrated liquid whose main enzymatic activities are β-xylanase and β-glucanase obtained from a fermentation broth of Penicillium funiculosum. The main active substances are endo-1,4-β-xylanase (EC No. 3.2.1.8 – minimum activity 350 AXC units/ml) and endo-1,3(4)β-glucanase (EC No. 3.2.1.6 – minimum activity 500 AGL units/ ml). There are a further 19 enzyme activities, including cellulase (endo-1,4-β-glucanase). Specific Gravity: pH: Freezing point:

1.09-1.13 3.7-4.2 -5°C

Use

Rovabio® Excel LC may be incorporated into animal feed by spraying onto pelleted feedstuffs to hydrolyse pentosans and β-glucans in vegetable raw materials.

The effect of this activity is to:

• Improve the nutritional value of feeds containing different types of cereals (wheat, maize, barley, triticale, rye, oats, etc) and oilseed meals (soybean, sunflower, canola, etc).

• Reduce gut viscosity. • Reduce the free ammonia concentration in the litter. Dosage/administration

Dose: Use at a rate of 0.2 litres Rovabio® Excel LC/tonne of feed.

This dose rate is equivalent to: xylanase – 70 AXC units/kg feed. β-glucanase – 100 AGL units/kg feed.

Administration: This product can be diluted with water in all proportions before spraying onto feeds.

It is recommended to check enzyme activity in feeds using the Rovabio® Test Kit.

Package sizes

200 litre drums delivered in full 800 litre pallets only.

1000 litre IBCs.

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Further information

Methods of analysis: Details of the methods for analysing activity and assay methods are available upon request. Storage: Rovabio® Excel LC is stable for 12 months from the manufacturing date when stored in its original sealed container below 10°C. At room temperature (max 30°C), it may be stored for six months after removal from cold storage (max 12 months from manuacturing date). Safety: A safety data sheet for Rovabio® Excel LC is available on request. There are no active micro-organisms in the final product. Safety in feed: Once incorporated into the feed, the product offers all original guarantees of safety. Handling: Handling the product may cause allergic reactions by inhalation during spraying.

◊ EU authorisation

Rovabio® Excel LC is approved as E1604 for broilers, layers, turkeys, ducks, pigs and piglets.

Supplier

Adisseo Berkhamsted House 121 High Street Berkhamsted Hertfordshire HP4 2DJ Tel: Fax: E-mail: Web:

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Rovabio® Max LC Presentation

new

Rovabio® Max LC is a concentrated clear to brown solution whose main enzymatic activities are β-xylanase, β-glucanase and phytase obtained from two fermentation broths, from Penicillium funiculosum and Schizosaccharomyces pombe. The main active substances are endo-1,4-β-xylanase (EC No. 3.2.1.8 – minimum activity 350 AXC units/ml), endo-1,3(4)-βglucanase (EC No. 3.2.1.6 – minimum activity 500 AGL units/ml) and 6-phytase (EC No. 3.1.3.26 – minimum activity 2,500 FTU units/ml). There is also cellulase activity. Specific Gravity: pH:

1.15-1.19 4.5-4.9

Rovabio® Max LC may be incorporated into animal feed by spraying onto pelleted feedstuffs to hydrolyse pentosans, β-glucans and phytates in vegetable raw materials.

The effect of this activity is to:

• Improve the nutritional value of feeds containing different types of cereals (wheat, maize, barley, triticale, rye, oats, etc) and oilseed meals (soybean, sunflower, canola, etc).

• Reduce gut viscosity. • Reduce the free ammonia concentration in the litter. • Reduce nitrogen and phosphorus excretion. Dosage/administration

Dose: Use at a rate of 0.2 litres Rovabio® Max LC/tonne of feed.

This dose rate is equivalent to: xylanase – 70 AXC units/kg feed. β-glucanase – 100 AGL units/kg feed. phytase – 500 FTU units/kg feed.

Administration: This product can be diluted with water in all proportions before spraying onto feeds.

It is recommended to check enzyme activity in feeds using the Rovabio® Test Kit.

Package sizes

1000 litre IBCs.

200 litre drums delivered in full 800 litre pallets only.

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Further information

Methods of analysis: Details of the methods for analysing activity and assay methods are available upon request. Storage: Rovabio® Max LC is stable for nine months from the manufacturing date when stored in its original sealed container below 10°C. At room temperature (20°C), it may be stored for six months after removal from cold storage (max nine months from manuacturing date). Safety: A safety data sheet for Rovabio® Max LC is available on request. Safety in feed: Once incorporated into the feed, the product offers all original guarantees of safety. Handling: Handling the product may cause allergic reactions by inhalation during spraying.

EU authorisation

Rovabio® Max LC is permanently approved as E1604 (carbohydrate activity) and 4a1640 (phytase activity) for broilers, layers, turkeys, ducks, piglets and fattening pigs.

Supplier

Adisseo Berkhamsted House 121 High Street Berkhamsted Hertfordshire HP4 2DJ Tel: Fax: E-mail: Web:

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Keep this Handbook up-to-date! When this Handbook was published, in February 2009, everything possible had been done by the publisher and product suppliers to ensure the information contained was accurate and up-to-date. Inevitably, some products will be subject to important changes between publication of this edition and the next. Whenever we are notified of changes to product information contained in this edition, these changes will be posted on our website at: www.simonmounsey.com/hbupdate.htm The updates will be in the form of replacement pages which can be printed out and used to replace pages in the original. As an additional service to users of this book, you may register to receive notification whenever an updated page is posted. Simply send an email to mail@simonmounsey.com with the subject line â&#x20AC;&#x153;Handbook Updates 2009â&#x20AC;? and your email address for notification.

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ROVIMIX® Hy•D® 1.25% Presentation

ROVIMIX® Hy•D® 1.25% is an off-white to beige, fine, free-flowing spray-dried powder of 25-hydroxyvitamin D3.

Uses

ROVIMIX® Hy•D® 1.25% provides a more bioactive form of vitamin D3 to the animal, which has proven advantages over vitamin D3: improvements in weight gain, feed efficiency, shell quality, laying persistence and reduction in bone disorders.

Dosage/administration

Maximum usage levels in feedingstuffs are:

Contra-indications/ precautions

Broilers Turkeys Laying hens

100 µg/kg 100 µg/kg 80 µg/kg

For animal use only. The product is safe for the intended use. Avoid ingestion, inhalation of dust or direct contact by applying suitable protective measures. For full safety information and necessary precautions, please refer to the respective DSM Material Safety Data Sheets.

Additive functional group

Vitamins, pro-vitamins and chemically well-defined substances having a similar effect.

Packaging quantities

Available in 25kg drum / bag.

Further information

ROVIMIX® Hy•D® 1.25% is sensitive to air, heat, light and humidity. The product may be stored for 12 months from the date of manufacture in the unopened original container and at a temperature below 15°C. The “best used before” date is printed on the label. Keep container tightly closed. Once opened, use contents quickly.

EU authorisation

ROVIMIX® Hy•D® 1.25% is permanently approved as E670a (i.e. as a source of vitamin D3) for chickens for fattening, turkeys and laying hens.

Supplier

DSM Nutritional Products (UK) Ltd Heanor Gate Heanor Derbyshire DE75 7SG

Tel: Fax: Website:

ROVIMIX® Hy•D® 1.25% is registered trade mark.

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ROXAZYME® G2 G Presentation

ROXAZYME G2 G is a practically odourless granulate which is soluble in water. It contains a stabilised and standardised enzyme complex derived from Trichoderma longibrachiatum. This complex includes endo-1,4-β-xylanase (EC/IUB No. 3.2.1.8 – minimum activity 26,000 units/g), endo-1,3(4)-β-glucanase (EC/IUB No. 3.2.1.6 – minimum activity 18,000 units/g) and endo-1,4-β-glucanase (EC/IUB No. 3.2.1.4 – minimum activity 8,000 units/g). The bulk density is approximately 0.61g/ml and the average particle size is approx. 550µm.

Uses

ROXAZYME G2 G has been demonstrated to be effective in improving the utilisation of feeds which are rich in non-starch polysaccharides (NSPs) (mainly arabinoxylans and β-glucans).

Dosage/administration

Recommended usage levels are: Broilers: Turkeys: Laying hens: Ducks: Piglets:

Contra-indications/ precautions

100g/tonne 100g/tonne 80g/tonne 100g/tonne 100g/tonne

For animal use only. The product is safe for the intended use. Avoid ingestion, inhalation of dust or direct contact by applying suitable protective measures and personal hygiene. For full safety information and necessary precautions, please refer to the respective DSM Product Specification and Safety Data Sheets.

Additive functional group

Digestibility enhancer.

Packaging quantities

20kg multi-walled paper sacks with plastic in-liner.

Further information

ROXAZYME G2 G is practically stable at room temperature, but may be affected by heat and humidity. The shelf life is 18 months from the date of manufacture when stored in the unopened original container and at a temperature below 25°C. The effective best used before date is stated on the label.

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EU authorisation

ROXAZYME G2 G is permanently approved as E1602 for chickens for fattening, turkeys for fattening, laying hens and piglets (to approximately 35kg) and provisionally approved for ducks.

Supplier

DSM Nutritional Products (UK) Ltd Heanor Gate Heanor Derbyshire DE75 7SG Tel: Fax: Website:

01773 536500 01773 536600 www.dsmnutritionalproducts.com

ROXAZYME速 is a registered trademark.

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ROXAZYME® G2 Liquid Presentation

ROXAZYME G2 Liquid is a stabilised, clear, brownish liquid, which is miscible with water. It contains a stabilised and standardised enzyme complex derived from Trichoderma longibrachiatum. This complex includes endo-1,4-β-xylanase (EC/IUB No. 3.2.1.8 – minimum activity 26,000 units/ml), endo-1,3(4)-β-glucanase (EC/IUB No. 3.2.1.6 – minimum activity 18,000 units/ml) and endo-1,4-β-glucanase (EC/IUB No. 3.2.1.4 – minimum activity 8,000 units/ml). The specific gravity is approximately 1.2g/ml.

Uses

ROXAZYME G2 Liquid has been demonstrated to be effective in improving the utilisation of feeds which are rich in non-starch polysaccharides (NSPs) (mainly arabinoxylans and β-glucans). It has been specifically formulated for post-pelleting application in the feed mill, which allows the benefits of