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SIBBIOPHARM COMPANY

BIOLOGICAL PRODUCTS FOR PLANT PROTECTION FROM DESTRUCTIVE INSECTS AND DISEASES PLANT GROWTH REGULATOR

2009


SIBBIOPHARM COMPANY has possibilities for placing of contract manufacture of biological production on following equipment: - fermenters with an automatic control system of fermentation process - vacuum-evaporating installation - filtering equipment: - filter-press and vacuum-drum press - installations for carrying out of micro- and ultrafiltration processes - spray drying equipment - flow centrifuge - pilot equipment (fermenters with programmable control, ultrafiltration installations, chromatograph Aktapurifier - modern labware and devices for the control of technological process and the acceptance control of finished product.


SIBBIOPHARM COMPANY

BIOLOGICAL PRODUCTS FOR PLANT PROTECTION FROM DESTRUCTIVE INSECTS AND DISEASES PLANT GROWTH REGULATOR

2009


SIBBIOPHARM COMPANY

SIBBIOPHARM COMPANY Sibbiopharm is a modern biotechnological company which: Produces a wide range of products to use in agriculture, forestry and food industries, health protection and ecology. Have modern facility with 600 m3 fermentation capacity and all downstream. Use modern systems of product quality control. Cooperates with the leading research and educational centers in Russia and abroad.

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SIBBIOPHARM COMPANY

Within the last decades biological products based on microorganisms and their metabolites are used to protect plants from destructive insects and agents of diseases. Active agents of bioproducts are the components of natural biocoenosis that is why they are safe for the environment, people, mammals, birds, fish and useful entomofauna. Sibbiopharm Company produces: Biological insecticides LEPIDOCIDE and BITOXYSIBACILLIN, Biological fungicides BACTOFIT and PLANRIZ, Plants growth regulator GIBBERSIB. These products are produced by means of submerged cultivation of germ cultures with subsequent concentrating of culture liquids and standardization of products. Reliable quality of products is provided by means of meeting the regulations requirements and control over technological parameters on all stages of production process: starting from the tube with producer strain in the laboratory and ending with acceptance control of finished products.

Main advantages of microbiological Plant-protecting agents High efficiency when used correctly. Selective ability when used with a broad spectrum of destructive insects and phytopathogens. Ability to solve the problems of destructive insects and phytopathogens population immunity to chemical pesticides with the help of microbiological Plant-protecting agents. Compatibility with chemical and biological pesticides. Safe for people, warm-blooded animals, hydrobionts, bees, entomophages when used in recommended standards of usage.

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LEPIDOCIDE LEPIDOCIDE

BIOLOGICAL INSECTICIDE

Lepidocide is a biological insecticide, which is used to protect forests, agricultural crops, and parks from caterpillars of lepidopterous insects like silk moths, black arches, geometrid moths, pea moths, sod webworms, cabbage and turnip white butterflies, fall webworms, thorn butterflies, owl-moths, moths, etc. Lepidocide can be used in agriculture and forestry, farmland and urban plantations. Preparation formula Graining bacterium Bacillus thuringiensis var. kurstaki is the active basis of the product. Active ingredient is sporo-crystal complex. Inert carriers ensure the product safety, flowing, adherence and stability. Protein toxin contained in the product leads to the general paralysis of the insect alimentary tract within first four hours after ingression into the stomach. Then, within 12-24 hours general bacterial hematosepsis of the insect organism starts to develop. When the dose is sufficient caterpillars stop eating, moving, change their color, shrivel, turn black and die within 3-7 days. Sublethal doses provoke metamorphosis disturbance, lowering of insect's reproductive performance and next generation's viability. Method of application of Lepidocide in forestry In forestry, Lepidocide is applied by means of spraying of plants by ground and aircraft means. Suspension concentrate is used as a finished product or diluted with water. Maximum protective effect of Lepidocide application is achieved when treating trees and bushes at early larvae instar (1-3) at air temperature of (18-30) оС. The practice of Lepidocide application for forest protection demonstrated a high efficiency of the preparation in control of phytophages (80-95%) and its harmlessness for beneficial entomofauna of biocenosis. Commodity form: suspended concentrate Lepidocide SC and SC-M, powder Lepidocide P Warranted Term of Storage: powder - 1 year and a half at temperature of (-30) - (+30)º С; suspension concentrate - 1 year at temperature of (+5) - (+30)º С Packing: Lepidocide SC and SC-M is packed by 20-50 L into polyethylene jerricans. Lepidocide P is packed by 10 kg, 15 kg and 20 kg into vacuum-sealed polyethylene bags. -3-


SIBBIOPHARM COMPANY

Lepidocide in forestry Lepidocide in form of suspended concentrate (SC and SC-M) has been applied in forestry since 1997. Annually Lepidocide provides an efficient protection of forests over area of 150-300 thousands ha. Consumption rate of Lepidocide against forest pests Culture

Pests

Conifers

Pine moth, nun moth, geometrid moth, pine beauty moth

3 l/ha

Oak and other leaf-bearing trees

Gypsy moth, geometrid moth, brown-tail moth, pea-green oak twist

3 l/ha

Consumption rates

Method of application of Lepidocide in forestry In forestry, Lepidocide is applied by means of spraying of plants by ground and aircraft means. Suspension concentrate is used as a finished product or diluted with water. Maximum protective effect of Lepidocide application is achieved when treating trees and bushes at early larvae instar (1-3) at air temperature of (18-30) оС. The practice of Lepidocide application for forest protection demonstrated a high efficiency of the preparation in control of phytophages (80-95%) and its harmlessness for beneficial entomofauna of biocenosis. Commodity form: suspended concentrate Lepidocide SC and SC-M, powder Lepidocide P Warranted Term of Storage: powder 1 year and a half at temperature of (-30) - (+30)º С; suspension concentrate - 1 year at temperature of (+5) - (+30)º С Packing: Lepidocide SC and SC-M is packed by 20-50 L into polyethylene jerricans Lepidocide P is packed by 10 kg, 15 kg and 20 kg into vacuum-sealed polyethylene bags. The use of Lepidocide in agriculture Lepidocide is applied in agriculture by means of surface method of spraying of plants. Suspended concentrate is used cut and dried or is watered. Water suspension is prepared by dispersing powder in water before usage. The product is recommended to use in dry weather in the morning or evening. Maximum protection effect of Lepidocide is reached when processing plants at the beginning of the caterpillars' growth (age I-III) at air temperature of 18-30˚C. Lepidocide consumption rates in case of the most abundant leaf-eating pests Consumption rates Culture

Pests

Green crops

Cabbage white and turnip butterfly, cabbage, grass and meadow moths

Horticultural crops Apple, codling and ermine moths, fall webworm, moth Small-fruit crops

Leaf-roller, gooseberry fruit and geometrid moths, gooseberry sawfly

Grapes

Grape moth

Suspended concentrate

Powder

0.5-1.0 l/ha

0.5-1.0 l/ha

1-3 l/ha

1-3 l/ha

1-1.5 l/ha

1-1.5 l/ha

2-3 l/ha

2-3 l/ha

Main advantages Works selectively relating to the broad spectrum of destructive lepidopterous insects. Is not phytotoxic. Does not accumulate in plants and fruits. Ensures ecologically clear and harmless to health product. Can be applied on any stage of the plant growth. Safety interval is 5 days which makes it possible to use shortly before harvesting. Is compatible with chemical pesticides and biological products. Is recommended for usage in the integrated pest suppression systems. Can be used to solve problems of the destructive insects population resistance to the chemical pesticides. -4-


BITOXYBACILLIN BITOXYBACILLIN

BIOLOGICAL INSECTICIDE

Bitoxybacillin is a biological insecticide intended for protection of herbs and agricultural plants against the following pests: red spider mite, Colorado beetle (larvae instar 1-3), worms of cabbage, grass, meadow, silkworm, geometrid, apple, ermine moths, cabbage white, turnip and whitethorn butterflies, leaf rollers and others. Preparation formula: Active agents of Bitoxybacillin are bacterial spores, protein crystals (delta- endotoxin) and heat-stable β-exotoxin of Bacillus thuringiensis var. thuringiensis. Inert fillers provide safety, wettability, spreadability and stability of the preparation. Method of application: Bitoxybacillin is applied by means of spraying of plants by ground means using any spraying machine. It is recommended to spray plants mornings and evenings under dry weather conditions. Maximum protective effect of Bitoxybacillin is achieved when treating plants at early larvae instar (1-3) at air temperature of (18-30) °С. Commodity form: powder Bitoxybacillin P Warranted Term of Storage: 1 and a half year at temperature of (-30) - (+30) ºС. Packing: by 10 kg, 15 kg and 20 kg in hermetically sealed polyethylene sacks.

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SIBBIOPHARM COMPANY

Bitoxybacillin consumption rates against the most abundant pests Culture

Pests

Greenhouse cultures

Red spider

Flowers and herbal

Meadow, noctuid, geometrid moths; leaf rollers, painted lady

2-3 kg/ha

Nightshade family

Colorado beetle

2-5 kg/ha

Horticultural crops

White butterflies; meadow, noctuid, pyralid moths

1-2 kg/ha

Leaf rollers, fall webworm, apple worm, whitethorn butterfly, sawflies, red spider; pyralid, geometrid, silkworm moths

2-5 kg/ha

Grape moth

6-8 kg/ha

Small-fruit

Grapes

Consumption rates 10-30 kg/ha

Mode of action: Intestinal nature of action is determined by crystallized proteic substance included as a compound of Bitoxybacillin. After penetrating into pest organism, the preparation causes intestine dysfunction; as the result feed rates decrease. β-exotoxin down-regulates RNA synthesis in pests' cells. Mass mortality of pests begins on the 3nd-7th day. Bitoxybacillin in sublethal doses inhibits feeding, breaks metamorphosis period, decreases female prolificacy and next generation viability (antifeedant and metatoxical effects).

Main advantages Bitoxybacillin Effective in protection against wide range of lepidopterous insects, red spider, Colorado beetle worms and other insects.

Bitoxybacillin Not phytotoxic, not accumulates in plants and fruitery.

Bitoxybacillin Guarantees ecologically clean, safe-health production.

Bitoxybacillin Can be applied at any phase of plant development.

Bitoxybacillin Expectation period is 5 days, that allows to spray plants shortly before harvesting.

Bitoxybacillin Compatible with chemical and biological pesticides in tank mixtures.

Bitoxybacillin Can be applied in case of pests autodefense to chemical pesticides.

Bitoxybacillin Recommended to be applied in integrated plant protection systems.

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BACTOFIT BACTOFIT BIOLOGICAL FUNGICIDE AND BACTERICIDE

Bactofit is a biological fungicide and bactericide Bactofit is a biological preparation meant for fungal and bacterial plant disease control for Flowers and herbs. Bactofit is meant for: - treatment seed grains and tubers before bedding - treatment of root system in case of replanting - spraying of plants or wetting during vegetation season - employment in common with herbicides. Blumeria graminis

Bactofit is produced on the basis of IMP-215 strain of microbial culture Bacillus subtilis and yielded in form of suspended concentrate (SC) and wettable powder (WP). The preparation retains its biological activity in soil and on plants from 7 up to 20 days.

Preparation formula:

Blumeria graminis

Bactofit consists of the following ingredients: - spores and cells of producer-culture - metabolites exhibiting antagonistic and antibiotic - inert fillers providing the preparation safety and stability. Optionally the preparation can be additionally completed with potassium (natrium) lignite and microelements (Mn, S, Cu, B, Fe, Zn, Mo)

Commodity form: suspended concentrate Bactofit SC wettable powder Bactofit WP Warranted Term of Storage: Bactofit SC - 6 months at temperature of (-25) - (+25)掳小. Bactofit WP - 2 years at temperature of (-30) - (+30)掳小. Packing: Bactofit SC - by 20-50 l in polyethylene canisters. Bactofit WP - by 5,10,15, 20 kg in vacuum-sealed polyethylene bags.

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SIBBIOPHARM COMPANY

Bactofit consumption rates in case of the most abundant diseases Culture

Disease

Grain crops

Root rot, Oidium, Septoria blight, Fusarium blight, Pyrenophora blight, Rust

Horticultural crops

Oidium, Root rot, Buck eye rot, Bacterial blights

Small-fruit

Oidium

2 l/ha

Grapes

Oidium

2-3 l/ha

Consumption rates 2-3 l/ha

2-3 l/ha

Bactofit application technology depends on plants development stage. Maximum efficiency is achieved at combination of secondary tillage and vegetative plants treatment. Grain crops treatment is recommended to be combined with herbicides chemical weeding of seeds. In this case Bactofit has an antistress effect on plants and increases yield capacity on 10-15%.

Main advantages: Bactofit Effective in protection against wide range of blights causative agents. Bactofit Has growth-stimulating, immunomodulating and antistress effects. Bactofit Active in conditions of moisture stress. Bactofit

Can be applied at any phase of plant development. Safety interval is 1 day that allows to treat fruits and vegetables during ripening period. Bactofit

Not phytotoxic, not accumulates in plants and fruitery. Bactofit

Recommended to be applied in integrated plant protection systems. Bactofit

Compatible with chemical and biological pesticides in tank mixtures. Bactofit

Not causes phytopathogene resistance that allows plant treatment till positive take.

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PLANRIS PLANRIS

BIOLOGICAL UNGICIDE AND BACTERICIDE Planris is a biological ungicide and bactericide. PLANRIS is a bacterial preparation based on vital cells of culture Pseudomonas fluorescens, strain АР-33. It protects: - corn against foot rot, Septoria spot, brown rust, spot disease - cabbage against wilt disease, stump rot, black stem - potato against several deseases - grapes against mildew, oidium, gray mold - sugarbeet against storage decay. It is applied for: - pretreatment of seeds - spraying of plants and root wetting in the vegetation period- cultivation of white beet roots before storing.

Blumeria graminis

Acting agents: - cells of producer culture - metabolites possessing antagonistic antibiotical and growth-promoting properties.

Commodity form: suspended concentrate Planris SC

Warranted Term of Storage: 30 days from the date of manufacture at a temperature of 4-8°С.

Packing: 10-20 l polyethylene jerricans. Late blight disease of potato

12

Grape mildew

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SIBBIOPHARM COMPANY

Planris consumption rates in case of the most abundant diseases Culture

Disease

Small grains

Root rot Brown rust Septoria spot Storage decay

Green crop

Root rot, Microsporiosis Phytophthora rot Rhizoctonia rot Fusarium blight

Small fruit

Gray mold

4 l/ha

Grapes

Mildew Oidium Gray mold

4 l/ha

Consumption rates 0,375-0.5 l/ha

0,3 l/ha

Main advantages: Planris suppresses growth and development of a wide spectrum of causative agents of plant diseases. Except of fungicide and bactericidal effect, it renders growthstimulation action. It can be applied in any phase of development of plants. Planris has no expectation period that allow to carry out processing in maturing period of fruit, berries, vegetables. Planris does not oppress vital functions of native bacterial microflora. Planris is compatible with chemical pesticides and groundfertilizer preparations. Planris does not cause formation of resistance at phitopathogens that allow to carry out processings repeatedly, till a positive result will be received.

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GIBBERSIB GIBBERSIB Main advantages Gibbersib possesses a wide spectrum of activity (maturing acceleration, growth stimulation, formation of parthenocarpic fruits) Gibbersib regulates leading metabolic processes by small doses Gibbersib does not influence taste and color of fruits and seeds of processed plants Gibbersib has no expectation period Gibbersib is harmless for man, warm-blooded animals, birds, fishes, bees Gibbersib does not pollute environment

PLANT GROWTH REGULATOR

GIBBERSIB is a natural plant growth regulator. It is received on the basis of microbic culture Fusarium moniliforme.

Active agent Complex of sodium salts of highly active gibberellins А3, А7, iso-А3, iso-А7. Gibberellins represent the most extensive and important group of the phytohormones which are belonging to the class of terpenoids. Gibbersib raises productivity and quality of vegetable, fruit and berry crops by: - growth stimulations and development of plants - increase of ovaries quantity - accelerated maturing of a crop - Increase of stability to diseases and adverse weather conditions - formation of parthenocarpic fruits.

Consumption norms of Gibbersib Vegetable crop..................................20-30 g/hа Solanaceous crops................................15-40 g/hа Leguminous crops......................................6-20 g/hа Grape (seedless types)...................0,9-1,2 kg/hа

Way of application Gibbersib is applied by spraying plants during the different periods of growth depending on the wished result. Commodity form: Powder Gibbersib (P)

Warranted term of storage: 2 years at temperature under natural conditions.

Packing: by 100g, 200g, 10kg, 15kg, 20 kg in hermetically sealed bags.

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LIST OF PRODUCTS Plant-protecting agents Lepidocide Bitoxybacillin Bactofit Planris Plant growth regulator Gibbersib Enzymes AmiloLux - A Amilosubtilin G3х Low-temperature amylase Temperature-stable amylase Protosubtilin G3х CelloLux - A CelloLux - F Glucavamorin G3х GlukLux-F Kormomix-enzyme Multienzymes Antibiotics for animals Bacilichin Biovit Feed mixes Fermolux Fermolux-P Kormomix-complex Kormomix-molasses Sillage agents Biosib Ferkon Larvicidal agent Bacticide Agent for water and soil purification from oil pollution Destroil


2009 Sibbiopharm Company 11 Khimzavodskaya str., Berdsk, Novosibirsk region, Russian Federation, 633004 Tel/fax: Reception: +7 (38341) 5-80-00, 5-80-23, Sales department: +7 (38341) 2-96-17, 2-96-18 Office in Moscow: Tel/fax: +7(495) 785-71-30; Office in Krasnodar: +7(861) 259-76-24; Office in Ryazan: +7(4912) 24-10-31; Office in Belarus: (37517) 335-05-65. E-mail: sibbio@sibbio.ru website: www.sibbio.ru

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