http://www.seipub.org/sepacs/paperInfo.aspx?ID=9049
Recent evidences suggested that metabolites themselves can be oncogenic by altering cell signaling and blocking cellular differentiation. The advances in cancer metabolism research over the last decade, have enhanced our understanding regarding the aerobic glycolysis and other metabolic alterations that are associated with cell growth and proliferation. The blocked apoptosis in malignant diseases, which may be due to high ATP concentration, originating from anaerobic metabolism. The difference of energy between anaerobic ATP into B and T lymphocytes in peripheral blood samples from hematopoietic malignant diseases measured by bioluminescence, was 2.68 µM ATPthat appears as an energetic transfer between normal T and B cells, initial with normal bio-energetic values. This energetic level could initiate the process of carcinogenesis by the supression of anti-oncogene proteins from its normal activity. The anabolic metabolism in B