“Immediate Effect of Talocrural Joint Manipulation on Foot Function in Subjects With Dorsiflexion Lag.” Smriti Mishra Background: A considerable research is published on effect of spinal manipulation but there is scarcity of literature on peripheral manipulation. This study investigated the immediate effect of talocrural joint manipulation on foot function. Objective: The purpose of the present study was to investigate the immediate effect of talocrural joint manipulation on foot function in subjects with dorsiflexion lag. Study Design: Pre-test post-test study design. Method: Sixty subjects with 5° or more of dorsiflexion restriction were recruited. Talocrural manipulation was given to all subjects. A single, short level, high velocity low amplitude distractive (caudal) thrust was directed at the talocrural joint. The procedure was performed with subject in supine line position. Pre and post test measurements of dorsiflexion range of ankle, joint position error and single leg stance test were documented. Results: Results were analyzed by using T-test. There was significant improvement (pre and post intervention) in all the three variables i.e dorsiflexion range of motion (p<.001), joint position error (p<.002) and single leg stance(p<.001). The increased dorsiflexion range could be associated with any release of minor adhesion, alteration of position of an intra-articular loose body or any reduction in muscle spasm by affecting the input through gamma loop system. The reason behind improvement in joint position error could be the effect of manipulation on muscle spindle which could have caused a further improvement in balance. Conclusion: We conclude that talocrural manipulation has an immediate effect in increasing dorsiflexion range of motion, decreasing joint position error and thus enhancing stability of joint. Key words: Dorsiflexion lag, manipulation, joint position error, single leg stance.