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Chemical Connections

Vol. 9 December, 2012

The official newsletter of the Department of Chemistry and Biochemistry

500 El Camino Real, Santa Clara, CA 95053 EMAIL: TELEPHONE: (408) 554-4799

SCU graduate Jessica Koehne - among recipients of the Presidential Early Career Award for Scientists and Engineers (PECASE) Editor’s Note: We are delighted to congratulate Jessica for her accomplishment and award, and greatly appreciate her generosity in sharing her career highlights

Since graduating from the SCU Department of Chemistry in 2000, my career has led me on an exciting journey. Although I have experienced some challenges along the way, my foundation in chemistry from SCU has given me the skills and confidence to adapt and seek opportunity. I am currently a research scientist for the NASA Ames Center for Nanotechnology where I develop biosensors for crew health and water quality monitoring applications. My research is truly interdisciplinary giving me the opportunity to work closely with electrical engineers, chemical engineers, materials scientists, biologists and medical doctors. I also support many programs through the NASA Office of Education, where I am given the opportunity to mentor students who are often unsure of career paths in science. Working with students frequently reminds me of myself at that stage of my career. In the SCU Department of Chemistry, we are so fortunate to Jessica is second from right, front row have the most dedicated group of faculty who are eager to guide and mentor young aspiring scientists on everything from experimental design to career paths to proper ethical conduct for scientists. I aspire to pass on the same guidance and values to students coming through my lab. 2012 has been the most exciting year of my professional career thus far. In July, I was awarded a Presidential Early Career Award for Scientists and Engineers (PECASE), which took me to the White House to meet President Obama and White House Science and Technology Advisor John Holdren. After getting the news that I was receiving the award, I immediately shared the announcement with the SCU Department of Chemistry through an e-mail to Dr. Shachter. Much of my career path and values are rooted in the education and experiences I had while in the department. For the official White House press release, go to


CONGRATULATIONS - 2012 Graduates

The department thanks the following alumni and guests for joining us at a wine and cheese reception on Grand Reunion weekend:

John Abdou Margaret Abercrombie Jennifer Brousseau Ryan Cheu Charles Denault James Ellis Carmelino Galang Rachel Gate Max Giammona Paul Henry

Frank DeLorenzo Jean Sugikawa Fujiki Cynthia Gonzalves Patty Hora

Keoni Murphy Peter Reck Richard Saita John Takla

A BIG thank you to Keoni Murphy for encouraging his friends from the class of ’82 to attend the department reception. Hope you will join us at future Grand Reunions.

Stanley Hiew Allen Kim Sarah Ludwig Ryan Lynch (Dec) Andrew Martinolich Megan Morisada Elena Naderzad Marc Nakashima Fritz Seidl Dustyn Uchiyama

From the Chair’s Corner

Jack Gilbert

The past year has again been an exciting time for the faculty, staff, and students of our department. I hope that this column serves to share some of that excitement with you. New Faculty From the stand-point of faculty news, we are delighted to welcome Paul Abbyad to the department as a tenure-track assistant professor. Paul is a biophysical chemist who joins us after earning his Ph.D. at Stanford University and doing postdoctoral work at the Ecole Polytechnique in Palaiseau, France, for several years. More information about Paul’s background and research interests is provided elsewhere in this newsletter. The addition of Paul brings the number of our tenure-stream faculty members to 11. Three are full professors, four are associate professors, and the remaining four are assistant professors. In addition, two full-time administrators, Dennis Jacobs, University Provost, and Atom Yee, Dean of the College of Arts & Sciences, hold positions as full professors in our department as well. Department Majors In last year’s newsletter, I noted that the number of our chemistry/biochemistry majors was 119, an all-time high. This figure continues to increase, as it now stands at 141, about two-thirds of whom are majoring in biochemistry. We are beginning to bulge at the seams in the truest sense, but are making every effort to accommodate our majors not only in classrooms but in research laboratories as well. Although we don’t truly understand the basis for the increase, it may be associated with renewed emphasis on STEM (Science, Technology, Engineering, and Mathematics) majors. In this context, we see growing numbers of students in our service courses (general and organic chemistry). Comparing enrollments from five years ago with those this fall, for example, the number of students in general and organic chemistry has risen from 411 and 138 students, respectively, in 2007 to 547 and 238 this year. Once they graduate, what are our students doing? The way to find this out is to visit and read the documents that are there. For example, what you’ll see for last year’s 21 seniors who appear in the brochure, most are planning to continue on to graduate or professional school after working (or resting!) for a year or more. The career plans include a law degree and an MBA, an indication that a degree in chemistry/biochemistry can lead in a number of directions. Award Winners As you know, our faculty place a high priority on quality teaching, so we were particularly pleased that Elisabeth Thomas, an academic staff member, received

the Dr. David E. Logothetti Teaching Award from the College of Arts and Sciences this year. This award is given “In recognition of having established among colleagues and students a well-deserved reputation for an energetic, engaging, and effective teaching style, and having demonstrated the ability to motivate other teachers and learners.” Elisabeth fits this description to a tee, having been an outstanding instructor in our general chemistry program for some 20 years, and thousands of students have benefited from her caring instruction. I would note that this is the first time that a staff member has received this teaching award! Our alumni and students have been garnering awards too. As noted above, Jessica Koehne (2000) was one of 96 recipients of the Presidential Early Career Award for Scientists and Engineers. Emilee Sena (2011) won an NSF Graduate Research Fellowship in this year's competition; Stan Hiew (2012) was awarded an Honorable Mention. I'm delighted to tell you that Stan has been named as the winner of the Gerald and Sally DeNardo Senior Prize in Science Research and Brett Yurash is one of this year’s DeNardo Science Scholars. Please join me in congratulating them as well as Amelia Fuller their research mentor. External Review Finally, the department is engaging in preparations for an external review, wherein two or more faculty members from other universities will assess our program and provide feedback, pro and con, to ourselves and administrators. The assessments can be of considerable value, as reflected in the last time such as review was performed. One of the key recommendations was that we offer more upper-division electives for our majors. Fortunately, the administration agreed to this, and we are now able to offer two such electives, up from one, each year. We need to increase this figure to at least three, and efforts are underway to do so. Parting Note This year marks my last as chair of the department. It has been a great pleasure for me to serve in this capacity since January 2007, as it has brought me into contact with a number of faculty, staff, In this issue and administrators from Award Winner 1 throughout the university as well as our alums. I look forward to Chair’s Corner 2 supporting my successor, who Chem Club 3 will be selected by the end of the Sigma X 3 spring quarter. I am confident that Awards 4 whoever it is will provide New Courses 5 exceptional leadership during Faculty News 6 her/his term as chair. For my own Alumni Corner .9 part, I thank you for all the Donations Report 9 support you provide to the Seminar Program 10 department.

DEPARTMENT NEWS Chem Club Accolade:

The Sweetest Day is the third Saturday in October. To celebrate, we had the pre-sweetest day pie social on the preceding Friday afternoon. Faculty, club officers, and students came together to share their love of pie!

Kudos to Dr. Linda Brunauer for her mentorship of the I like SCU Chem Club. The SCU Chem Club continued its pie! 20-year uninterrupted string of awards from the American Chemical Society this year, adding a Commendable Chapter Award to our collection of plaques! This year, besides sponsoring a new “Sweetest Day” pie event and a TRP Turkey (sandwiches) Break for the department, Chem Club members continue to volunteer their services to the community, such as presenting hands-on scientific activities at MLK Library during National Chemistry Week. Members also participate in the scholarly ACS Undergraduate Research Conference, held at Mills College in Spring 2011. Seemed like everyone who came was rewarded in one way or another!

I like pie!

I like pie!

I like pie!

I like pie!

Do you like pie?

Photos courtesy of Drs. Linda Brunauer & Korin Wheeler Left: Hands-on Activities at MLK Library Below: Mills College ACS Undergraduate Research Conference, Spring 2012 (Megan Morisada and Erick Castellanos Jimenez)

Sigma Xi Twelve students were recognized for their substantial research accomplishments in collaboration with faculty in Chemistry & Biochemistry through their induction to Sigma Xi, the honor society for scientific research: John Abdou, Ryan Cheu, Rachel Gate, Stanley Hiew, Nathaniel May, Megan Morisada, Meagan Nakamoto, Marc Nakashima, Vincent Nguyen, Fritz Seidl, Emily Tran, and Dustyn Uchiyama. Newly inducted members presented their research at a poster session held on campus in the spring quarter. Clockwise: Stan Hiew, Fritz Seidl, Rachel Gate Photos Courtesy of Dr. Steve Suljak

SCU DeNardo Awards In case you missed it in the Chair’s Corner, we’re proud to reiterate here that Chemistry/Biochemistry majors swept the DeNardo Awards. Stan Hiew (2012) has been named as the winner of the Gerald and Sally DeNardo Senior Prize in Science Research. Brett Yurash (2013) is one of this year’s two DeNardo Science Scholars, as is Emily Robinson (2014).

NSF Awards As noted in the Chair’s Corner, Emilee Sena (SCU Chemistry '11) won an NSF Graduate Research Fellowship in this year's competition. Stan Hiew received an Honorable Mention.

Chemistry 2012 Award Winners

Phi Lambda Upsilon Nominees Fritz, Stan, Sarah & Megan

CRC Freshman Chemistry Achievement Award Awarded to a freshman student for outstanding performance in General Chemistry Recipient: Scott Kravitz American Chemical Society Polyed Award Sponsored by the Polymer Education Committee of the American Chemical Society to honor outstanding achievement in Organic Chemistry Recipient: Courtney Holmes American Chemical Society Award in Analytical Chemistry Given to an upper-division student for excellence in both lower- and upper-division analytical chemistry courses Recipient: Nathaniel W. May American Institute of Chemists Foundation Award Awarded to an outstanding senior chemistry major in recognition of a record of leadership, ability, character, and scholastic achievement Recipient: Stanley Hiew American Chemical Society Award in Inorganic Chemistry Awarded to an undergraduate student who has demonstrated excellence in inorganic chemistry and whose future plans include a career in chemistry. Recipient: Stanley Hiew

Phi Lambda Upsilon Membership-at-large in this National Honor Society in recognition of a record of leadership, ability, character, and scholastic achievements. Nominees: Stanley Hiew, Sarah Ludwig, Megan Morisada and Fritz Seidl Joseph Deck Award Established in 1973, this award is given by the Chemistry Department faculty to the outstanding student majoring in chemistry who has excelled in studies and undergraduate research, extracurricular activities, leadership and generous tutoring of fellow students, while maintaining at least a B average,. Recipients: Max Giammona and Megan Morisada

New Upper-Division Electives in the Department of Chemistry & Biochemistry In the past year, the department has introduced two new electives to the curriculum. In spring 2012, Dr. Suljak taught a seminar style course in Bioanalytical Chemistry, and in winter 2013 Dr. Hoggard will be teaching an upper-division elective focusing on Environmental Chemistry.

Environmental Chemistry (by Patrick Hoggard) For many years our department has taught Chemistry 1, Chemistry and the Environment, to non-majors, who take it to fulfill a core requirement, but we’ve never offered a course on environmental chemistry for students who actually know some chemistry. This will change in the winter quarter of 2013, when I will be offering this as a Special Topics course (Chem 190). One theme that runs through many aspects of environmental chemistry is that so much of it consists of free-radical reactions. Most of the reactions taking place in the

stratosphere, including those that affect ozone formation and depletion, are free radical reactions. That yellow layer you see covering Los Angeles as the plane descends, or as you drive down into the valley on Highway 395, develops all over again every day through free-radical reactions. The decomposition of many organic pollutants in the soil – free-radical reactions. Water purification by chlorination – more free radicals. In Chemistry 1, you can scarcely even mention the term free radical, much less go into mechanisms, rates, steady

state concentrations, and photochemical yields, but those are precisely what make the subject so interesting. And then there’s global warming. It’s one thing to talk about changing all your light bulbs to compact fluorescents to save the environment or, on a grander scale, to pledge to reduce carbon dioxide emissions to 1990 levels. It’s another to look at the models that predict anthropogenic warming, to look at the equations, to see how many variables there are, and to evaluate what the range of variability is for each. As

an example, we’ll look at “radiative forcing” and “relative instantaneous radiative forcing” and how they affect predictions for the future of the climate. Finally, we’ll examine the problem of where energy will come from in the future and what chemistry research is offering to the solution of that problem,

particularly in the design of cheaper photovoltaic materials and solar energy storage possibilities. I’ve never enjoyed talking about the chemistry of the environment to nonmajors. I always feel like I’m pontificating, that whatever I say the students have to accept because I’m the

instructor. I’m eagerly awaiting the chance to teach this special topics course where students will be able to see the science behind the issues, including even the uncertainties in areas where our knowledge is less than perfect.

Bioanalytical Chemistry (by Steven Suljak) Since my arrival at SCU in 2004, I have looked forward to the opportunity to teach a course focused on current topics in bioanalytical chemistry. The biological realm provides a vast array of challenges to the analytical chemist. Biological samples tend to be complex, unstable, and available only in small amounts. Modern analytical methods have been pushed to remarkable limits by the motivation to gain quantitative information about the chemistry of living systems. With each improvement in instrument sensitivity, spatial resolution, and temporal response, new truths about biological systems at the molecular level have been revealed. The tandem progression of analytical

FACULTY NEWS New Assistant Professor Paul Abbyad Paul Abbyad joined our faculty in September after spending four years at the Laboratory for Optics for Biosciences and the Laboratory for Hydrodynamics, which are located at the Ecole Polytechnique near Paris. As you might imagine, it was no mean task to lure Paul away from that location, but we are delighted that we managed to do so with strong support from Dean Yee and his staff. Prior to his sojourn in France, Paul earned his Ph.D. with Steven Boxer at Stanford, after completing his B.S

methods and biological insights was the central theme of this new course. The class was conducted seminar style, with each lecture session focused on the discussion of one or two articles from recent literature in the field. Students read extensively on topics including separations of single vesicles, proteomics (and metabolomics and peptidomics), microfluidic systems, invivo voltammetry, microdialysis, biobarcodes, and nanoflares. In addition to learning about the science itself, a significant portion of each discussion was directed at skills in reading scientific literature – students had the opportunity to critically evaluate how effective the papers were in

communicating the science through the writing, figures, and tables, while also considering how convinced they were by the experimental results presented. Each student also wrote an extensive review article on a bioanalytical topic not featured in the course, with subjects ranging from magnet-activated cell sorting to single molecule analysis via electrochemical detection in nanofluidic devices. In response to student feedback from this spring, I am also excited to note that Bioanalytical Chemistry has recently been approved as a course to satisfy the Advanced Writing core requirement at SCU!

(Honors) in Chemistry at McGill University in Montreal. While at Stanford, he not only excelled in the research laboratory and the usual array of required science courses, but also took “Science Course Design” and “Issues in Science Education for Science and Engineering Grad Students”, both of which will serve him well as a faculty member here. He is currently teaching our upper-division course in biophysical chemistry and will continue to offer additional courses in physical and general chemistry.

will continue his scholarship here at SCU.

Paul has an impressive publication record, already having 12 papers as a co-author. These have appeared in prestigious peer-reviewed journals such as Proceedings of the National Academy of Sciences, Biochemistry, and Journal of Physical Chemistry B. In addition, he has made numerous presentations at international conferences. We are confident that Paul


Speaking of scholarship, Paul’s research interests are in the field of microfluidics, studies of the flow of liquids in micrometer-sized channels. Within this area, he is particularly interested in microfluidic droplets, an emerging technology that expands applications by confining reagents and cells in small droplets that do not mix and therefore represent “test tubes” of nanoliter volume. Applying this approach to biological and chemical assays results in a reduction in the volume of reagents required and a concomitant decrease in the costs of such assays. We are pleased to welcome Paul as well as Barbara Stübner, his recent bride, who is a talented musician and linguist in her own right.

Suljak’s Research Group Steven Suljak’s research group continues its efforts to develop aptamers to distinguish between protein variants with specific posttranslational modifications, currently focused on a cancer-linked protein called thrombospondin-1. In addition, a collaboration with the Birmingham lab (SCU Physics) and Kim lab (Bioengineering) involves investigating the changing levels of biogenic amines in crab hemolymph using a combination of bioanalytical techniques ranging from LC-MS/MS to micro- fabricated chip electrophoresis with electrochemical detection (funded by a grant from Research Corporation). Four group members (Megan Morisada, Nate May, Ryan Cheu, and Dustyn Uchiyama) presented posters on their research at PittCon 2012 in Orlando. In addition, several members presented posters at this year’s ACS Undergraduate Research Meeting. Megan, Ryan, and Dustyn graduated from the lab this past May; As seen in the picture Megan clearly won the award for the largest collection of leis!  Lab alumni report that they are doing well. Christian Paquet and Rob Pivec are in residency programs, seven others are continuing medical school, and five alumni are immersed in doctoral research programs. Chappy Huang recently began pharmacy school at California Northstate University near Sacramento. And in more personal news, Mary Lucas became Mary Oransky after getting married to David Oransky in July! Wendy and I have enjoyed meeting with alumni both in Santa Clara and during our travels in the past year.

Updates from the Adalsteinnson Group Last academic year, the unusual situation came up that every group member Kyle Tubbs (biochemistry), Paul Henry (biochemistry), Vincent Nguyen (biochemistry), Marc Nakashima (biology), Emily Tran (biology), John Abdou (chemistry) and Charles Denault (Chemistry), were scheduled to graduate in the spring. This meant a complete turnover of students, which started in the winter quarter. The group published one article last year in the Journal of Physical Chemistry B; "Phase transitions of n-hexadecane in nanoencapsulated binary solutions of n-hexadecane and 1-octanol." by Kyle W. Tubbs, Vincent T. Nguyen and Thorsteinn Adalsteinsson. Other contributions made by this group included a joint publication with Dr. Barber (physics) and Dr. McNelis (chemistry and biochemistry) this last academic year; "Transport and Spectroscopic Studies of the Effects of Fullerene Structure on the Efficiency and Lifetime of Polythiophene-based Solar Cells: by E. L. Sena (2011) et

The 2012 graduating group Kyle, Paul, Vince, Marc, Emily, John and Charles al.; presentations at the local ACS undergraduate research symposia and the Sigma Xi symposium at SCU. Emily Tran continued working on her research project during the summer months. She was joined by a fellow graduated biology student, Amar Sandhu, in order to complete the research project. In October 2012 Dr. Adalsteinsson submitted his petition for promotion to tenure and the rank of associate professor. In the spring quarter, Dr. Adalsteinsson recruited and trained three students to continue the research projects. New group members are Connor Lynch (bio-engineering), Kaitlyn Trillo (chemistry), Aakash Agarwal (biochemistry). Bianca Khishaveh (chemistry) and Julia

Nguyen (biochemistry) joined the lab during the Fall quarter. This current group is working on two new research projects, one journal article and two research proposals, which will hopefully serve to maintain the high level of

activity in the group. The hope is to contribute material to the Gordon conference and to the American Physical Society meeting this year in addition to the regular contributions to the ACS meetings. Given these activities, there are no vacations planned this year.

News from the Fuller Lab The Fuller lab is continuing research on peptoid structure, and we’re making slow but steady progress. Last fall the department bought a new mass spectrometry system with funds from a grant from the National Science Foundation, and that’s been a useful instrument in our research. Currently, three students are doing undergraduate research on projects in the Fuller lab: Courtney Holmes (’14), Erik Schaumann (’13), and Brett Yurash (’14). We also welcomed Belem Avila this fall. Belem is a postdoc who got her Ph.D. from UC Davis. In addition to teaching a few courses here at SCU, Belem is working in both the Carrasco and Fuller labs and starting to get familiar with peptoids. In the past academic year, Fuller lab researchers made a number of research presentations. Both Stan Hiew (’12) and Fritz Seidl (’12) made oral presentations at Mills College at the Northern California Undergraduate Research Symposium last spring. These two also presented on campus at the Sigma Xi poster session and gave a research talk at our final departmental seminar. In addition, Courtney, Erik and Brett all attended the 8th Peptoid Summit in Berkeley, CA with Dr. Fuller this past August, and Brett presented a poster. Courtney Several of our lab members earned some impressive honors for their scientific

excellence this past academic year. Courtney Holmes won the American Chemical Society Polyed award for excellence in organic chemistry, Brett Yurash was recognized as a Gerald and Sally DeNardo science scholar, and Stan Hiew was awarded the DeNardo Senior Prize in Science Research as well as the American Institute of Chemists Foundation Award. Fritz and Stan were also inducted into Sigma Xi, the science research honor society, and Phi Lambda Upsilon, the national honor society for excellence in chemistry. Fuller lab alumni are doing really well too! Paul Bruno (’10) is now officially a Ph.D. candidate at the University of Michigan in Michigan in Anna Mapp’s lab, so congrats to Paul on passing that milestone! Kanwal Palla (’10) has joined Matt Francis’s lab at UC Berkeley and will have her preliminary exams this spring. Lauren Sartor (’11) is putting the finishing touches on a publication as a graduate student at CSU Northridge. Marisa Plescia (’11) is teaching science at a high school nearby. We bid farewell to three awesome graduates this past June. Although we’re sad to see them go, I know they’ll do great things after SCU. Stan Hiew is in the chemistry graduate program at UC Irvine, and Fritz Seidl just started in the chemistry graduate program at Stanford. Kasey Conklin is applying to medical schools this year. You can look forward to hearing about their accomplishments in future editions of this newsletter!

News from the Wheeler Lab We’ve had a busy year in the Wheeler lab. Our research group grew in the fall with the addition of two new members, Erick Castellanos-Jimenez (‘13) and Kristian Borofka (‘14). With a total of six members, the lab was always full and buzzing with activity. In 2012, our first paper was published! This initial chapter of our research focused establishing the impact of silver nanoparticles on the structure and function of copper proteins essential to healthy cells. Since silver nanoparticles are being incorporated into many new consumer products as an antimicrobial, this research provides insight into the antibacterial effects of the particles, as well as potential routes of toxicity. The work was published in the journal Environmental Science and Technology. Andrew Martinolich (‘12), Meagan Nakamoto (‘12), Grace Park (‘13), and Rachel Gate (‘12) all made their debut in the scientific literature as undergraduate coauthors on the paper.

(Right to left): Andy Martinolich (’12), Dr. Wheeler, and Meagan Nakamoto (’12) at graduation.

To present the next phase of our work, Rachel Gate and I attended the American Chemical Society meeting in San Diego in March. Rachel presented a poster on her work in the bioinorganic chemistry poster session. I gave an oral presentation in the inorganic chemistry session. We both had a great time exploring new restaurants in San Diego. We also met many great researchers in the field and came back to SCU excited to test new ideas in the lab and expand our research to new areas. In the spring we were both proud and sad to see three of our group members graduate. Meagan Nakamoto is headed off to vet school at Colorado State University. Meagan is still doing research in one of the labs in the vet school during her spare time. Andy Martinolich and Rachel Gate both stayed in the field of biochemistry and are working closer to their SCU homes. Andy is at Innova, a small bioenergy start up in the East Bay and Rachel is in Dan Minor’s lab atup UCSF.Our other group alumni, Alyssa Lampe (2011), left her research position at Lawrence Berkeley Labs this year to attend medical school at University of Southern California. Although the group is now scattered around the country, it is great to see everyone find success in their different fields. We are a smaller and quieter research group this year. Grace (’13), Erick (’13), and Kris (’14) are all working hard and keeping the instruments in constant use. We are looking forward to sharing an exciting set of new results in the next installment!


(1984) wrote from the mountains in

Switzerland: I graduated in 1984. Dr Yee arrived at SCU my junior year and sparked some life into the department. After SCU I participated in the wave of start-up biotech/ medical devices in the Silicon Valley for almost 20 years. Six years ago adream prompted me to venture to Europe. I landed in Belgium (not Italy as intended) in a big company. In BE I found my path to energy/plants/spirits/healing et mon amore. Two years ago, Switzerland/Lausanne became our home... A stunning natural beauty with immediate access to nature/outdoor sports and activities and work in a small medical device start-up. My focus is on the energy/plants/spirits/healing and part-time at the start-up medical device company. Life is good and full. This past summer, we asked Emilee Sena (2011) to share more on how she won the NSF Graduate Research Fellowship and what she planned to do with it, she responded: I have spent the last year as a first-year physical chemistry graduate student at UC Berkeley, where I worked on magnetometry in the lab of Alex Pines and taught CHEM 1A to college freshmen in the fall. My proposed graduate research project was a novel miniaturized NMR spectrometer that integrates an optically-pumped diamond magnetometer and remote detection techniques on a microfluidic device. This was proposed to be done in the lab of Dr. Pines, my advisor at UC Berkeley, who is known world-wide for his work in solid state NMR spectroscopy.

A hearty THANKS to all for the news you sent us! To our readers: we love to hear from you. Please send us your stories A couple of weeks ago I learned that I was awarded an NSF fellowship. NSF has some basic guidelines on how I may use it, for instance I must be getting a research-based graduate degree in science or engineering. It is transferrable with NSF approval. I intend to use it to get a Ph.D. in Chemistry or Chemical Engineering, and I am striving to combine my love for chemistry, math, physics, and materials science. I hope to use my fellowship and education to encourage young women and minority students to pursue careers in science and engineering. This is especially important to me because I am half Hispanic, even though my red hair makes that hard to see. ;) Congratulations to Shawna Hengel (2002) upon her completion of her Ph.D. She shared her story with us: I was in the 2002 class at SCU. While at SCU I worked in Dr. Carrasco's lab, and took many classes from Dr. Nathan with Dr. Brunauer being my course adviser for the first few years. I am happy to hear that Dr. Sweeney is still active in the program, I have fond memories of his lectures. I worked in biotech in South San Francisco for two years before going to grad school in the Medicinal Chemistry department at the University of Washington. I worked for David Goodlett whose lab primarily focuses on proteomics using high resolution mass spectrometry. I did global proteome profiling, but a large majority of my thesis work was on characterizing the post-translational modification ADP-ribosylation using mass spectrometry. After completing my PhD at UW, I did a post-doc at Pacific Northwest National Laboratory in the

Environmental Molecular Sciences Laboratory. It's a national laboratory through the Department of Energy,

use mass spectrometry to characterize both small and large molecules. So far so good, but I still feel like I just started!

where I worked with high resolution mass spectrometry. It is located in eastern Washington, in Richland

We recently learned that Jason Tarver (1997) is a defensive coordinator for the Oakland Raiders. Congratulations, Jason. Good luck to you and the Raiders.

I just started a new job as a staff scientist at Seattle Genetics in the Bioanalytical Development group, where I

Gifts This is a gentle but important annual reminder that donations you make as a means of giving back to Santa Clara University and the Department of Chemistry & Biochemistry provide resources to support a variety of needs, many of which are directed toward students. Included among the diverse uses we make of your contributions are defraying the expenses of students who are attending scientific conferences, purchasing equipment to support teaching laboratories and scholarly research, and paying banquet expenses for our majors when they are initiated into honor societies such as Sigma Xi. A contribution this fiscal year assumes particular significance because the Leavey Foundation will donate $1,000,000 to the university if 9,000 undergraduate alumni make a contribution prior to July 1, 2013. We are confident that our grads have special memories of their experiences at SCU and in the department, so in that context, please seriously consider making a tax-deductible contribution for the betterment of our program and the university. In the newsletter next year, we would dearly like to be able to report a large increase in the number of individual gifts made. As you can see from the table below, we seem to be “stuck” in the low 20s! Rest assured that no contribution is too small to provide us with a benefit so please consider making a donation. Thanks in advance for helping us meet our financial needs and creating an even more vibrant department as a result! Fiscal Year

No. of Amount ($) No. of Special Amount ($) Individual Gifts Gifts* 2007 21 4,080 2 46,530 2008 21 6,025 1 61,201 2009 20 10,580 2 104,325 2010 23 11,530 2 110,708 2011 22 10,440 0 N/A 2012 22 4,934 0 N/A *Sources: Deck Family Trust, Ted Welp Science Fund, Mary Johnson Trust

You can make your gift by mailing it to:

Total Amount ($) 50,610 67,226 124,907 122,238 10,440 4,934

Department of Chemistry & Biochemistry, Santa Clara University 500 El Camino Real Santa Clara, CA 95053 Attention: Lourdes Barretto

Or you can also make a gift online at: Follow the link to the “Online” menu, select “College of Arts & Sciences” in the box provided, and then under “Gift Information”, specify an amount for the gift and then either select “Joseph F. Deck Fund” or “Other” in the “Designation” box; for the latter, enter Chemistry Gifts in the box provided. Finally, click on “Add Donation” Then scroll down to complete the information requested. Sounds more complicated than it really is and it’s a very convenient way to donate to us.

Seminar Program Our seminar program features speakers who cover a wide range of scientific topics of interest to our faculty and students. Overseen by Dr. Korin Wheeler (2011-12) Term Fall, 2011

Winter 2012

Spring, 2012


Speaker/Affiliation Dr. Matthew Francis, UC Berkeley. Dr. Jen Heemstra, University of Utah. Dr. Babak Sanii, Molecular Foundry Dr. Keir Fogarty, University of Minnesota Dr. Paul Abbyad, Ecole Polytechnique, Paris Advanced Biosciences Initiative Symposium Keynote speaker: Prof. Matt Bogyo, Stanford. Dr. Gareth Butland, Lawrence Berkeley National Laboratory. Dr. Matt Law, UC Irvine. Dr. Monika Sommerhalter University of California State, East Bay. Dr. Evan Powers, Scripps Research Institute. Dr. Paul Weiss UC‐Los Angeles. Dr. Matthew Sazinsky Pomona University. Dr. Hilary Godwin, UC‐Los Angeles. SCU Students

Using Biological Molecules to Make New Materials Small‐Molecule‐Dependent Split Aptamer Ligation Knobs Formanipulating Biomaterials: Bending Lipid Membranes and Buckling Peptoid Monolayers in 2D Nanosheets Fluorescence Fluctuation Spectroscopy to Study HTLV‐1 Virus Sickling of Red Blood Cells in Microdroplet Arrays Small Molecule Probes of Protease Function: Applications to Molecular Imaging and Drug Discovery Assembly and Functional Characterization of Etalloproteins and Their Cofactors Developing Earth Abundant and Quantum Dot Materials for Thin‐Film Photovoltaics Acetylcholinesterase from Tritonia diomedea The Enhanced Aromatic Sequon for Protein N‐Glycosylation. Designing, Measuring, and Controlling Molecular and Supramolecular Devices Insights into the Regulation of Enzyme O2 Use and Diabetic Iron Acquisition Environmental Implications of Nanotechnology Various

Chemical Connections 2012