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Emerging Technologies: Stem cells Published on November 2011

Report Summary Introduction Stem cell therapies will play an increasingly important role in the underserved field of regenerative medicine, as preclinical discoveries are translated into the clinical setting and product candidates slowly progress through a diverse pipeline. Features and benefits * A full stem cell pipeline by each therapeutic category from preclinical stage to registration candidates. * Provides an insight into key players, recent deals and developments. Highlights Small and medium-sized research-led companies dominate the stem cells landscape, with a few large pharmaceutical companies beginning to invest in recent years. The stem cells sector is highly heterogeneous, consisting of different technology platforms, including embryonic and adult stem cells, applied in a wide range of therapy areas. Geron's recent divestment in the sector highlights the several technical challenges associated with the application of stem cells in certain therapy areas, in particular, the central nervous system. Your key questions answered * Assess the key challenges and opportunities expected to shape the sector in the near term. * Benchmark the competitive landscape within the stem cell sector, identifying the key pipeline candidates and most active disease areas of development.

Table of Content Executive Summary Strategic scoping and focus Datamonitor key findings Recent updates ABOUT THIS REPORT PharmaVitae Explorer database Chapter structure Introduction to stem cells Stem cell pipeline Key players Data sourcing INTRODUCTION TO STEM CELLS

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>> Get this Report Now by email! Key findings An introduction to stem cells Types of stem cells Pipeline snapshotAlthough bone marrow stem cell transplant has been routinely used for over 4 decades to treat hematological malignancies, the potential of stem cells to regenerate or replace highly specialized damaged or lost tissues in serious degenerative disorders or debilitating diseases, such as myocardial infarction, spinal cord injuries, ischemic stroke, macular degeneration, diabetes, and multiple sclerosis, has yet to be realized. Key limitations that still need to be addressed include successful delivery, differentiation, engraftment, integration, vascularization, functionality, and long-term safety of the transplanted cells. In view of this, several companies are currently exploiting more easily achievable goals, using a more drug-like approach that utilizes stem cells to alter physiological conditions within the damaged tissue and that indirectly promotes repair and regulates inflammatory and immunomodulatory pathways. SWOT analysis Strengths Opportunities Weaknesses Threats STEM CELL PIPELINE Key findings Stem cell pipeline overview Cardiovascular Central nervous system Ophthalmology Endocrine and metabolic disorders Immunology and inflammation Musculoskeletal Other indications THE KEY PLAYERS Overview Mesoblast Osiris Therapeutics Athersys Gamida Cell Cytori Therapeutics Geron APPENDIX References Datamonitor research Journal papers Exchange rates

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Emerging Technologies: Stem cells  

IntroductionStem cell therapies will play an increasingly important role in the underserved field of regenerative medicine, as preclinical d...

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