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Bronchogenic Carcinoma: Inci: Non-small CA (Adeno> Sq > Large cell) > small CA/ Meta: LN > adrenal > liver > brain > bone Name

Location

Pathology

其他

Non-Small Cell carcinoma Squamous Cell Carcinoma

Proximal

Papillary, basaloid, Intercelluar bridge, keratin pearl, salt-pepper chromatin, 全部都是核/細胞質少 Combined (sq. Cell CA + adeno CA)/早期、廣泛的 Metastasis 流程:Goblet Cell→Basal Cell→Sq. Cell (metaplasia, malignancy

M>F 98% Smoker

change)→Sq. Cell (Dyssplasia)→CA in situ→Invasive Non-squamous cell CA Adenocarcinoma

Peripheral

Acinar, papillary, solid carcinoma, mucin formation 較沒有症狀

Microvilli 短胖

Bronchioloalveolar: pneumonia-like consolidation, in situ, lepidic Large Cell Carcinoma

Central-located

Varient: neuroendocrine basaloid 無角質化/ 無 intracellular bridge

Small cell CA 以 mitosis 和 Necrosis 區分

Neuroendocrine CA

Low grade: Typical carcinoid Intermediate grade: atypical carcinoid High grade: Large cell/ small cell carcinoma, 有小花環狀 Others Metastatic tumor

Multiple nodules

Extrathoracic tumor 的 Multiple 轉移 Lymphangenic, endobronchial, embolic, solitary ※Chylothorax: 因腫瘤阻塞造成的淋巴外滲

Malignant mesothelioma

Pleura

Asbestosis (30 年的前潛伏期) Epitheloid, sarcomatoid, Mesothelio cell 用 Calretinin 染

Thymus

Epithelial cell, Hassall corpuscle

Myoid cell. (肌樣)

Thoracic Tumor Pathology [2014.01] NYMU 10001085

DiGeorge syndrome: Thymic hypoplasia Thymic cyst: variable epithelium Lymphoma: thymic epithelial cell with benign 未分化 T Cell, 重症肌無力

Microvilli 細長

可能 invade 或轉移 成年, >40yrss


Thoracic Tumor Pathology [2014.01] NYMU 10001085


Pathology thoracictumor