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Studies open voor inclusie – Afdeling Hematologie Acute Myeloïde Leukemie Externe code

Titel

Onderzoeker

InDACtion vs. induction: 10-day decitabine versus conventional chemotherapy EORTC1301 -

(3+7) followed by allografting in AML patients ≥ 60 years: a randomized phase III

Velden, van der

AML21

study of the EORTC Leukemia Group, CELG, GIMEMA and German MDS Study

W.J.F.M.

Group

Chronische Myeloïde Leukemie Externe code

Muscle function

Titel The relation between muscle function and muscle pain in patients with chronic myeloid leukemia (CML): a pilot study

CMyLife

The impact of CMyLife on quality of life, information supply, patient

effectmeting

empowerment and guideline and medication adherence in patients with CML

Zorgpad analyse

Pathways of care that lead to a sustained and deep treatment response in

CML

chronic myeloid leukemia

Onderzoeker

Blijlevens, N.M.A.

Blijlevens, N.M.A.

Blijlevens, N.M.A.

Chronische Lymfatische Leukemie Externe code

Titel

Onderzoeker

A phase 3 multicenter, randomized, prospective, open-label trial of standard chemoimmunotherapy (FCR/BR) versus rituximab plus venetoclax (Rve) versus HOVON140

obinutuzumab (GA101) plus venetoclax (Gve) versus obinutuzumab plus ibrutinib

Croockewit, A.J.

plus venetoclax (GIVe) in fit patients with previously untreated chronic lymphocytic leukemia (CLL) without del (17P) or TP53 mutation

Studies open voor inclusie – Afdeling Hematologie – Radboudumc Juni 2018

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MDS Externe code

Titel

Onderzoeker

A prospective, multicentre European Registry for newly diagnosed patients with EU-MDS NL

Myelodysplastic Syndromes (MDS), including acute myeloid leukaemia with 20-

Langemeijer,

30 percent marrow blasts (former RAEB-t), and Chronic Myelomonocytic

S.M.C.

Leukaemia (CMML)

Lymfomen Externe code

Titel

Onderzoeker

Efficacy of alternating immunochemotherapy consisting of R-CHOP + RHAD HOVON119

versus R-CHOP alone, followed by maintenance therapy consisting of additional lenalidomide with rituximab versus rituximab alone for older patients with mantle

Stevens, W.B.C.

cell lymphoma

HOVON127

Phase III study comparing R-CODOX-M/R-IVAC versus dose-adjusted EPOCHR (DA-EPOCH-R) for patients with newly diagnosed high risk Burkitt lymphoma

Stevens, W.B.C.

Autologous transplantation after a rituximab/ibrutinib/ara-c containing induction in HOVON133

generalized mantle cell lymphoma – A randomized European MCL network trial

Stevens, W.B.C.

(TRIANGLE) HOVON900

A national MYC screening study in relation to the HOVON 130 protocol

Stevens, W.B.C.

Multipel Myeloom Externe code

Titel

Onderzoeker

Pomalidomide combined with carfilzomib and dexamethasone (PCd) for induction and consolidation followed by pomalidomide combined with HOVON114

dexamethasone vs pomalidomide maintenance for patients with multiple

Croockewit, A.J.

st

myeloma in first relapse after prior 1 line treatment with lenalidomide and bortezomib

Studies open voor inclusie – Afdeling Hematologie – Radboudumc Juni 2018

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Stamceltransplantatie Externe code

Titel

Onderzoeker

Vaccination with PD-L1/L2-silenced minor histocompatibility antigen-loaded PSCT19

donor DC vaccines to boost graft-versus-tumor immunity after allogeneic stem

Schaap, N.P.M.

cell transplantation (a phase I/II study)

Supportive Care Externe code

ORASTEM

PIRANA

PACER

AZOR-man

Titel Oral complications in patients treated with hematopoietic stem cell transplantation Pharmacokinetics of posaconazole (Noxafil) as treatment for invasive fungal infections

Onderzoeker

Blijlevens, N.M.A.

Blijlevens, N.M.A.

A randomized controlled trial on prophylactic platelet transfusion prior to central

Velden, van der

venous catheter placement in patients with trombocytopenia

W.J.F.M.

PCR based detection of azole resistance in A. fumigatus to improve patient

Velden, van der

outcome. A prospective multicentre intervention study

W.J.F.M.

Safety and efficacy of interleukin-1 inhibitor anakinra for the amelioration of AFFECT-1

mucositis and fever during neutropenia in patients with multiple myeloma receiving an autologous hematopoietic stem cell transplantation after high-dose

Blijlevens, N.M.A.

melphalan Improving sleep quality, psychosocial functioning and cancer related fatigue with

Spronsen, van

light therapy

D.J.

Citrullinebeloop bij patiënten met autologe en allogene stamceltransplantatie

Blijlevens, N.M.A.

Externe code

Titel

Onderzoeker

PRO-RBDD

Prospective data collection on patients with rare bleeding disorders

Laros, B.A.P.

SPARKLE

Citrulline sampling

Stolling

Studies open voor inclusie – Afdeling Hematologie – Radboudumc Juni 2018

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EUHASS

GO-ITI

OPTI-CLOT

DAVID

Little DAVID

European haemophilia safety surveillance system registry GO-ITI study, genetic determinants of ITI outcome in patients with severe haemophilia A Peri-operative pharmacokinetic-guided dosing of clotting factor in hemophilia DDAVP treatment combined with FVIII clotting factor concentrates in patients with mild hemophilia A Desmopressin and FVIII concentrate combination treatment in non-severe hemophilia A patients undergoing minor interventions

Laros, B.A.P.

Laros, B.A.P.

Laros, B.A.P.

Laros, B.A.P.

Laros, B.A.P.

HemoNED

Landelijk register van patiënten met hemofilie en aanverwante aandoeningen

Laros, B.A.P.

RBiN

Rare bleeding disorders in the Netherlands

Schols, S.E.M.

Hemoglobinopathie Externe code

STARRING

Titel Sickle cell disease: targeting alloantibody formation reduction; risk factors, and genetics

Onderzoeker

Schols, S.E.M.

PNH Externe code

Titel

RPNH01

Paroxysmal nocturnal hemoglobinuria (PNH) registry

AK581

Akari Long term safety Coversin

Onderzoeker Langemeijer, S.M.C. Langemeijer, S.M.C.

Indien u nadere informatie wenst over een studie van afdeling Hematologie, dan kunt u contact opnemen met het Trialbureau Hematologie, bereikbaar via telefoonnummer 024 – 3614794 en/of e-mail trialbureauhemat-onco@radboudumc.nl.

Studies open voor inclusie – Afdeling Hematologie – Radboudumc Juni 2018

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Hemat studies open voor inclusie 03 2017  
Hemat studies open voor inclusie 03 2017