Page 1

One Nucleus One Nucleus Directory 2017

Directory 2017


Markel. Expect more from your insurance provider

Specialist insurance solutions and complimentary services for the biomedical and life scrience sector: Insurance solutions – Public and products liability – Directors and officers – Professional indemnity – Property insurance

Tax and funding services – R&D tax relief – Patent box – Grant funding – Capital allowances

To find out more please visit: www.markelinternational.com/lifescience


Contents

Contents About One Nucleus Welcome One Nucleus Services Membership Benefits and Prices To Sponsor One Nucleus Our Corporate Patron Current Corporate Sponsors Partner Programme Life Science Leadership Series Genesis ON Helix Dates for your Diary Purchasing Scheme Facilities Management and Health and Safety Services Training Courses Special Interest Groups (SIGs) ON Hub European Activities Strategic Relations with Top US Clusters One Nucleus Collaborations One Nucleus Corporate Patron and Corporate Sponsors One Nucleus Partners One Nucleus Gold Members One Nucleus Silver Members Advertisers’ Index

4 6 8‑10 12 13 14 15 16‑17 18 19 20 23 24‑26 27 28 29 30 31 32 33 35‑37 39‑45 47‑77 79‑145 146

Produced and published by: Publishing Events Ltd 2nd Floor, Chapel House, 18 Hatton Place, London EC1N 8RU, UK Tel: 020 7841 5960 Email: guides@publishingevents.com www.publishingevents.com Disclaimer Neither One Nucleus nor the publisher recommends the products and services of any advertiser. All members’ entries have been supplied by the companies listed in the directory. While great care has been taken to ensure that the content of this directory is correct, neither One Nucleus nor the publisher of the directory accept responsibility for any error, omission or claim made in the directory. www.onenucleus.com | 3


About One Nucleus

About One Nucleus One Nucleus is an international membership organisation for life science and healthcare companies. We are based in Cambridge with the majority of our members across the Cambridge/London corridor – at the heart of Europe’s largest life science and healthcare cluster. Vision: For One Nucleus and our members to be the top European life science and healthcare network. Mission: We will achieve this by maximising the global competitiveness of our members. Organisation History Established in 1997, One Nucleus is a not‑for‑profit membership organisation located in Cambridge. We have over 470 organisations as members, including pharmaceutical, biotech, medical device and diagnostic companies and associated technical and commercial service providers. One Nucleus’ mission is to maximise the global competitiveness of our members. For our science and technology‑based members, that means them being global leaders in the research, development and commercialisation of healthcare innovations that radically improve the quality of people’s lives around the world. For our business and professional services members, it means them delivering exceptional services that significantly enhance the business performance of their clients.

4 | One Nucleus Directory 2017

The One Nucleus Family Collectively the membership forms a commercial, clinical and academic powerhouse. Around 80% of our members are based in the Cambridge/London corridor, an area that is home to at least 60% of the UK’s life science industry base. The corridor includes four of the UK’s five Academic Health Science Centres/ Networks and three of the world’s top six universities. Our membership reflects that the ‘corridor’ and network is an international life science ‘super cluster’, the largest in Europe by some way. Our member benefits include: l A large and significant pool of companies to support business to business interaction within the membership  Membership of a cluster of international size, relevance and visibility  Major impact both in the UK and overseas with the compelling excellence of our members articulated strongly to international organisations, institutions and governments for ultimate member benefit


GRADE A OFFICES AND LABORATORIES at Imperial College London’s new White City campus

FASTRACK TO CENTRAL LONDON

GROW TRANSLATE ENABLE

Translation & Innovation Hub (I-Hub) 80 Wood Lane, White City, London, W12 0BZ // Shell & Core laboratories available for tenant fit-out // Fitted laboratories & offices ready to occupy // Cat A office accommodation // Incubation and move-on space // Unique opportunity to co-locate with Imperial research groups // Close to Imperial’s medical campus at Hammersmith Hospital // 8 mins walk from Central, Hammersmith & City and Circle lines For details, contact Imperial College ThinkSpace: +44 (0)20 7594 5155

thinkspace@imperial.ac.uk


Welcome

Welcome Welcome to the One Nucleus Member Directory for 2017. I am delighted that One Nucleus continues to be the largest life science and healthcare membership organisation in Europe, with over 470 members. In 2016 we were awarded the honour of ‘Best Global Life Sciences and Healthcare Membership Organisation’ by Global Health & Pharma magazine, which the team and I were thrilled with and believe is testimony to the strength of each and every one of our members. This directory profiles all our members. Company details have been supplied to us by the organisations featured. I hope these will help you to identify old friends and also new potential partners, customers and suppliers from the One Nucleus family. We operate three levels of membership – Partner, Gold and Silver (with Partners receiving all Gold Member benefits). Please see inside for details of the benefits of membership if you haven’t yet joined us. Here at One Nucleus we are always keen to make everything we do as worthwhile and tangible as it can possibly be, and to scrutinise our services to ensure they fit with our members’ needs and business objectives. As an example, do read more on page 20 about our fast expanding ON Helix Conference and how we continue to evolve our Genesis Conference, in collaboration with SCRIP, on page 19.

6 | One Nucleus Directory 2017

We also continue to build on our international focus and (I like to think) global reputation. Do check out page 33 for details of our collaborations in the UK, and pages 31-32 to learn more about our strategic relations with the top US and European clusters. There is never a week that goes by in the One Nucleus team when we are not hosting, briefing or supporting an international opportunity for our members. If you are interested in finding out more about us and how we can help you to maximise your growth and competitiveness, do contact me or a member of the One Nucleus team and we will be delighted to help. Times do not get any easier for the life science and healthcare sector or the wider global economy. I hope that One Nucleus’ support has been worthwhile for our members to date and we very much look forward to continuing to serve them and new members throughout 2017.

Harriet Fear CEO, One Nucleus


Where Life Meets Science Chesterford Research Park offers state of the art laboratory and office space alongside superb central facilities a community perfectly positioned for today’s thriving pharmaceutical and biotech companies. WWW.CHESTERFORDRESEARCHPARK.COM

01223 358114 dodson-jones.co.uk

DODSON JONES C HAR TE R E D S U R V E YO R S

savills.co.uk

01223 347 000


One Nucleus Services

One Nucleus Services 1. Events Network Meetings (Cambridge) and BioWednesdays (London) Our networking meetings bring together our broad range of members for peer‑to‑peer debate around current trends, challenges and opportunities within the sector in an informal setting. Meetings are usually held in the evening, with presentations or panel debates sandwiched between ample time for networking. Attendance ranges between 50 and 150 delegates. Gold and Silver Member company employees are entitled to free entry. Non‑members are welcome, although are subject to a small charge. Genesis (London) Genesis has been running as our international life science conference since 2001. In partnership with SCRIP Intelligence and other partners, recent years have seen increasing depth and breadth of content and debate at Genesis, retaining a core biopharma theme and with a greater presence of digital health and medtech on the programme, reflecting the changing life science and healthcare landscape. Even more interactive leadership sessions, 1‑2‑1 partnering, workshops and bespoke hubs to source innovation, finance, R&D services and international opportunities respectively. A mark of the progress of Genesis is that it has now become a significant hub event, around which other organisations are increasingly planning

8 | One Nucleus Directory 2017

their own satellite events on the surrounding dates – now known as the Genesis Fringe. These elements, and the location of the conference at the heart of the world leading international business hub that is London, make Genesis a unique nucleus for the life science sector where delegates leave having gained maximal return on investment from their participation. ON Helix (Cambridge) ON Helix is our annual translational research conference for the life science industry. Launched in 2013, this one day conference aims to inform delegates of how to turn early stage inventions and ideas into innovative health treatments. It presents the UK landscape of the business environment, funding, scientific and clinical research excellence and is a unique knowledge‑sharing environment between academia and business. ON Helix combines keynote presentations from high profile global leaders, practical information, exceptional world‑class case studies and plenty of time for networking. Life Science Leadership Series Our Life Science Leadership Series are our bespoke events showcasing innovation that addresses specific areas of challenges for our members and the wider sector – whether by therapy area, technology discipline or business challenge.

Special Interest Groups (SIGs) We run a range of Special Interest Group (SIG) meetings for our Gold Members. Our SIGs include Human Resources, Operations which incorporates Facilities, Security & Business Risk, Health & Safety and Purchasing. The aim of these meetings is to provide a platform for people doing similar jobs in different companies to get together informally and discuss the issues that affect their working lives. Meetings are typically held three or four times a year, starting with a presentation on a topic nominated by the SIG, followed by discussion and lunch. One Nucleus reserves the right to exclude individual Gold Members from individual SIGs where we consider there to be a conflict of interest.


One Nucleus Services

2. Purchasing Scheme The One Nucleus Purchasing Scheme was set up to deliver low cost purchasing based on the combined spend of the purchasing consortium members. The scheme currently saves our purchasing consortium members over £4 million per annum. By joining together in the scheme, small businesses enjoy the same purchasing influence as larger companies and we are able to negotiate excellent prices and substantial savings in a number of product areas, including lab consumables, stationery and courier services. It is the largest and longest running scheme of its kind run by a membership organisation for the sector in the UK.

In addition to the Support Supply Agreements (SSAs) that are available to all One Nucleus members, Gold Members also have exclusive access to our Preferred Supplier Agreements (PSAs) – tendered agreements with various suppliers. Our suppliers are selected based on their ability to offer one or more of these criteria:  Substantial discounts (up to 50% off catalogue prices)  No delivery or handling charges  Guide payment terms of 30 days with the option of monthly consolidated invoicing  Delivery next day if in stock  Volume rebates for companies exceeding annual turnover targets Savings vary from company to company, but on average our members save over 35% on their annual spend.

3. Training Programme One Nucleus recognises that a company’s employees are its most valuable asset. Many rapidly growing companies overlook the need for ongoing training of their staff. One Nucleus has developed a portfolio of training courses designed to help life science and healthcare companies build an experienced and cohesive workforce. Employees should be able to contribute far beyond their technical capacity to enhance company growth and success as well as developing their personal skills. We have developed a range of tailored training courses based on the needs of our member companies. We are constantly developing courses on new subjects as our members’ needs change. With this in mind, we have extended our training reach in the UK and now offer our training courses in London as well as Cambridge. All of our courses can be adapted and tailored to meet your needs, and can be delivered cost‑effectively in‑house, both nationally and internationally. One Nucleus training courses are available to members and non‑members. Non‑members pay a commercial list price rate, while Silver Members receive a discount from the list price and Gold Members receive increased discounts off the list price plus priority booking.

www.onenucleus.com | 9


One Nucleus Services

One Nucleus Services continued 4. International Activities As an international membership organisation with global reach, we are delighted that we have continued to see companies from outside the UK join the One Nucleus family. Our international activities focus to a large extent on developing relations and tangible outcomes for our members with the US and wider Europe. That said, a wide range of our events and activities are specific to other markets and past events have included a focus on Hong Kong, Canada, Sweden, France and Australia to name but a few. In the US, we have formal relations with six of the top life science and healthcare membership organisations who support our members in accessing their networks and markets. In Europe, One Nucleus is a long‑term member of the Council of European BioRegions (CEBR) and continues to have excellent relations, not just with key cluster organisations across Europe, but with companies too.

5. Ask One Nucleus! The One Nucleus Dashboard Ever been frustrated by that need to ask someone for a quick piece of advice but not sure where to look? Often the advice sought is related to a topic covered at a recent meeting you have attended but you can’t quite remember the person who spoke. Help is at hand! Rather than reaching for the

10 | One Nucleus Directory 2017

web search engine, you can visit our website and ‘Ask One Nucleus’. Ask One Nucleus is our Dashboard service that provides members who are developing and managing a growing life science business with a one‑stop‑shop helpline for easily accessible advice from approved experts across a variety of specialised areas. The Dashboard allows for better and more timely sharing of expertise between members by making the

network available 24/7. By means of submitting an enquiry online, members can seek the sort of rapid expert guidance you would expect to receive when asking such an expert in person at a network meeting or conference. The Dashboard also provides newsfeeds and updates from our approved experts to stay abreast of industry developments such as regulatory changes, funding calls and new services.


SECURING INNOVATION

Award winning, full service, expert intellectual property services for the life science industry www.potterclarkson.com

PATENTS TRADE MARKS DESIGNS LEGAL


Membership Benefits and Prices

Membership Benefits and Prices We offer three levels of membership – Partner, Gold and Silver. Partners and Gold Members enjoy an enhanced range of exclusive services and benefits. The following benefits table compares the services available to Gold and Silver Members. Member Benefits Benefit

Non‑Member

Silver Member

Gold Member

   

   

   

£350 + VAT

£280 + VAT

£210 + VAT

Cambridge Networking Meetings

£50 + VAT per delegate

Free to attend

Free to attend

London BioWednesday Meetings

£50 + VAT per delegate

Free to attend

Free to attend

£425 + VAT

£275 + VAT

£145 + VAT

List price

15% discount

30% discount

  

  

  

Company Size

Silver Membership

Gold Membership

N/A

£190 + VAT

N/A

Start‑up company – available for the first year since incorporation to start‑up companies only

<10 employees

£285 + VAT

Free for the first year since incorporation

Micro company

<10 employees

N/A

£670 + VAT

Small company

<20 employees

£395 + VAT

£1130 + VAT

Medium company

21‑50 employees

£555 + VAT

£2950 + VAT

Large company

51‑150 employees

£690 + VAT

£4560 + VAT

150+ employees

£830 + VAT

£6950 + VAT

Profile in One Nucleus member Directory Post news on the One Nucleus website Post events on the One Nucleus website Post jobs on the One Nucleus website Genesis

ON Helix One Nucleus training Discounts under Support Supply Agreements (SSAs) Discounts under Preferred Supply Agreements (PSAs) Participation in Special Interest Groups

Annual Membership Prices Membership Level Individual / Sole Trader

Extra large company Partner Programme

12 | One Nucleus Directory 2017

For more information please contact tony@onenucleus.com


To Sponsor One Nucleus

To Sponsor One Nucleus At One Nucleus we appreciate the need to ensure that sponsorship delivers value for money to each individual sponsor. Moreover, we want to work with sponsors who can add real value to our core activities. In addition to membership, you can become involved with One Nucleus either as a Corporate Sponsor or by sponsoring one of our events. One Nucleus has a successful track record in providing a platform for people from all walks of the life science and healthcare community to meet and interact. We achieve this by hosting a wide range of events in Cambridge and London, exhibiting at national and international events, hosting delegations from overseas, publishing newsletters and maintaining a content‑rich website. Our mailing list currently includes over 10,000 contacts working in the global life science and healthcare sector.

One Nucleus sponsorship benefits:  Raising your company profile in one of the top cluster communities in the world  Aligning your organisation with the leading life science and healthcare network in Europe  Promoting your company via One Nucleus, not just to the Cambridge and London community, but to the global industry  Corporate Sponsorship attracts all Gold Member benefits If you would like to support One Nucleus as a Corporate Sponsor, please contact harriet@onenucleus.com.

Corporate Sponsorship benefits include: One Nucleus Correspondence  Your company name on the One Nucleus digital letterhead Website  Your logo featured on all pages of the One Nucleus website

One Nucleus Promotional Materials  Your logo on One Nucleus’ standard PowerPoint Presentation  Your logo on relevant promotional flyers  One Nucleus logo on your communications as appropriate

 Your company name listed on the Corporate Sponsors’ page of the One Nucleus website

 First refusal on further sponsorship opportunities such as our Network Meetings

 Your logo on the Corporate Sponsors’ page of the One Nucleus website with a hyperlink to your website

Events and Conferences  Distribution of your literature by One Nucleus at the national and international events where One Nucleus is exhibiting, e.g. MOU partner events

Newsletter  Your name on One Nucleus’ biannual ON Highlights newsletters

 One complimentary ticket to One Nucleus’ Genesis and ON Helix conferences

www.onenucleus.com | 13


Our Corporate Patron

Our Corporate Patron Here at One Nucleus we are delighted and honoured that MedImmune is our Corporate Patron. The company has worked very closely with us since the creation of One Nucleus in 2010. I am personally very pleased that Jon Green, Vice President, Site General Manager at MedImmune, continues to chair our board of directors. His insightful advice and thoughtful intelligence are pivotal in ensuring we retain our strong focus on delivering tangible benefits for all our members, and with a special focus on our SME members. As well as being on the same site (Granta Park), there is great interaction between the two organisations. Senior MedImmune scientists are on the Advisory Boards of many of our events, including ON Helix (our translational research conference in Cambridge). They are hands‑on and bring significant gravitas and knowledge to the programmes. We work alongside the MedImmune team to deliver their internal ‘Creating New Medicines’ course. And in other collaborative activity, I meet and present regularly to the Leadership Team at MedImmune on a range of subjects – from debates to internal teams to briefings for their IP lawyers. Jane Osbourn told me: “we deeply value our relationship with One Nucleus. As well as being the go‑to place for advice or information about what is going on in the sector, they have their finger on the pulse of what their members need. MedImmune thoroughly enjoys playing its part in this and I think it demonstrates our commitment to the wider ecosystem.” As I am sure most readers of this Directory will know, MedImmune is the worldwide biologics R&D arm of AstraZeneca. Committed to scientific innovation and medical progress, and contributing to all of MedImmune’s therapy areas, MedImmune’s team in Cambridge is the European biologics R&D base for oncology; respiratory, inflammation and autoimmunity; and cardiovascular disease. Recognised for their excellence in antibody discovery and protein engineering; disease understanding; biopharmaceutical development; clinical development; project management; legal, intellectual property; and regulatory affairs; the 600 or so MedImmune employees in Cambridge work in integrated project teams with colleagues in Gaithersburg and California. With one of the strongest, most robust pipelines in the industry, including more than 120 research projects and over 40 product candidates in clinical development, MedImmune comprises nearly half of AstraZeneca’s overall R&D portfolio. It is very clear from my interactions with MedImmune that our Corporate Patron has partnership and collaboration at the heart of its work. This is seen in its activities, not just with us (serving the sector more widely than purely MedImmune interests), but also with the University of Cambridge, Addenbrooke’s, the MRC Laboratory of Molecular Biology, Babraham Research Campus, Cancer Research UK, the Institute of Metabolic Sciences and a wide range of other collaborations and links with academics, researchers, charities, foundations and neighbouring companies. Long may it continue – I, for one, am hugely grateful for the personal and professional support we at One Nucleus receive from Jane Osbourn (Vice President Research and Development, and Cambridge Site Leader), Jon Green (our Chair) and the wider MedImmune team.

Harriet Fear CEO, One Nucleus

14 | One Nucleus Directory 2017


Current Corporate Sponsors

Current Corporate Sponsors Corporate Patron:

Corporate Sponsors:

www.onenucleus.com | 15


Partner Programme

Partner Programme The One Nucleus Partner Programme offers a fully integrated value proposition to organisations seeking to play an influential and visible role in the development of the life science community. Key Benefits: l Raises profile of the Partner with key investors, industry partners and stakeholders

l Positions the Partner as a key thought leader and in the sector in the minds of UK and international partners

l Offers a bespoke and tailored commitment to you from One Nucleus to help underpin and meet your business objectives

l Provides significant savings over the normal costs of benefits including additional benefits only available to One Nucleus Partners

l Provides access to training courses and events at free or vastly reduced cost to enable staff development

Working with our Partners: Engaging with our Corporate Sponsors and Partners in order to share insight, whether at events or via e‑communications is an important part of One Nucleus’ activities. Here are some examples of recent activities: l One Nucleus led on the delivery of a dementia research leadership day hosted at Eli Lilly’s Windlesham site. The day gathered over 100 high level delegates to debate leading approaches in the diagnosis, treatment and financing of dementia research and development. Plans are well underway to deliver further leadership and networking events in therapeutic fields such as the microbiome, immunotherapy and dementia, whilst we also explore more commercial themes such as working with mid‑sized pharma and engaging with the City. AstraZeneca provides numerous speakers and insight via our events and MSD are increasing their engagement in areas such as oncology, microbiome and investment. l Our Professional Services Partners provide specialist insights for our members. Penningtons Manches has hosted breakfast sessions on key topics including how employers can secure IP around interim staff engagement, preparing for an IPO and data protection strategies. Future topics may cover corporate finance options, IP licensing and real estate considerations for life science companies. Deloitte and Taylor Wessing add to this knowledge sharing through hosting breakfasts, leadership events and CEO Dinners. Hume Brophy bring expertise in accessing capital and communications. l Our One Nucleus Partners providing R&D facilities, such as Stevenage Bioscience Catalyst, BioMed Realty, London Bioscience Innovation Centre, Queen Mary BioEnterprises, Babraham Bioscience Technologies and Norwich Research Park engage to inform members and inward investors of their location options and to engage their own tenants in One Nucleus member benefits. l Our CRO and technical advisory Partners, such as PPD, Wellcome Trust Sanger Institute and Global Regulatory Services (GRS), support our members through provision of expert speakers and insight in fields such as precision medicine, international clinical trial procedures, ADMETox requirements and regulatory strategies. l Finally, our Partners in the business intelligence, communications, travel and bio‑partnering space, which include SCRIP Intelligence, PharmaVentures, First Sight Media, Pharmaceutical Training International, GlobalData, Assay Depot, EBD Group, United and Flight Centre Business Travel, provide our members with access to strategic advice and significant discounts on training, travel and major conferences. For more information about the Partner Programme (and costs), please contact Tony Jones at tony@onenucleus.com.

16 | One Nucleus Directory 2017


Partner Programme

www.onenucleus.com | 17


Life Science Leadership Series

Life Science Leadership Series Our Life Science Leadership Series (LSLS) continue to focus on showcasing innovation and addressing specific areas that challenge our members and the wider sector – whether it’s a therapeutic area, technology discipline or business challenge. In 2016 our LSLS evolved even further to answer the network’s needs and interests and they now consist of three streams: l Leadership Sessions – Half or full day events covering developments within a specific therapeutic area. For example, in 2016 we organised a session on the impact of genomics on drug development which was held at the Wellcome Genome Campus, Hinxton. The event covered new developments and programmes in genomics and biodata, highlighting their impact on the pharmaceutical industry and the processes of new therapeutics development. We have also covered other particularly relevant therapeutics areas for the industry including inflammatory respiratory diseases and dementia. Dementia is particularly relevant to the One Nucleus network in the context of the UK’s involvement in this area. l Innovation Sessions – Showcasing the latest technical solutions to challenges in R&D. Various topics around drug conjugation and pre‑clinical datasets have been covered, providing earlier stage companies within the network with a solid base to advance their research projects on the drug development pathway. l Business Intelligence Sessions – Data presentations and debates around key issues and innovation in business practice. These popular sessions have covered topics relevant to all businesses in the sector, including talent management, market access, clinical trial liability and equity financing – all discussed in small group sessions. Our LSLS are a very important aspect of engagement with our members as we create them upon members’ demand for topics and in collaboration with the right expertise in the network. Given the rich content of these events, we always publish speakers’ slides and also relevant articles from other organisations and often editorial known as ‘ON Insights’ – findings from the session are published on our website. If you would like to discuss any potential topic that represents an industry challenge for you or your organisation, or specific aspects of innovation, please contact our Business Development Manager, Aline Charpentier on 01223 896 451 or at aline@onenucleus.com.

A member of United Life Sciences

Representing over 1,240 Life Science and Healthcare companies in the UK

18 | One Nucleus Directory 2017


Genesis

Genesis Our annual Genesis conference continues to be one of the ‘must attend’ events in the life sciences and healthcare calendar. Assembling thought leaders and stakeholders from across the spectrum of the sector to debate key challenges, highlight current trends and celebrate successes, the event attracts over 750 delegates for a high content day in central London. Our Partnership with SCRIP and Datamonitor enables us to call on the business intelligence arising from the research and journalism of the Informa Group to ensure a significant depth of data and real world evidence is presented in order to help frame the day’s debates. An annual event, now in its 17th successful year, Genesis is an intensive one‑day event with a strong conference programme, exhibition, 1‑2‑1 partnering and networking. Moreover, recognising the pivotal role the event takes in bringing all stakeholders together in London, the satellite seminars that form the Genesis Fringe continue to provide additional return on investment for those staying in London either side of the main event.

Date: Thursday 14 December 2017 Venue: QEII Centre, Westminster, London Planned Highlights:  A first class agenda featuring an international speaker faculty developed in collaboration with SCRIP and Datamonitor that will include a mix of: ‑ Plenary key opinion leader presentations ‑ Case study deal debates ‑ Focused parallel leadership sessions ‑ Plenary debates on industry trends and challenges  1‑2‑1 partnering open to all delegates to review other delegates’ profiles and pre‑arrange key meetings throughout the day  The Genesis 2017 BioNewsRound Award  The Genesis Fringe  Welcome Reception  Exhibition spaces (3m x 2m) available from £850* + VAT and including one full delegate pass  Delegate fees starting from £210* + VAT * Price dependent on One Nucleus membership status and early booking. Spaces are allocated on a first come first served basis.

London’s premier Life Science & Healthcare networking conference 14 December 2017 QEII Centre, Westminster, London, UK genesisconference.com #ongc17

genesis 2017 www.onenucleus.com | 19


ON Helix

ON Helix Date: 13 July 2017 Venue: Wellcome Genome Campus, Hinxton, Cambridge ON Helix is now our established translational research conference in the UK calendar, addressing key themes with world class speakers through interactive case study sessions. The conference brings academia and industry together under one roof to bridge the gap between basic research and launching a product onto the market, a part of the drug discovery process that is not focused on at most other conferences around the UK. 2016 saw another great event with keynote addresses from Professor Sir John Savill, Chief Executive of the MRC; Dr Susan Windham‑Bannister, President and CEO of Biomedical Growth Strategies; Professor Nick Lemoine, Medical Director at NIHR; Professor David Roblin, Chief Operating Officer and Director of Scientific Translation at the Francis Crick Institute; and Dr Jane Osbourn, Site Leader and VP Research and Development, MedImmune. The One Nucleus team, along with an exemplary advisory board, have put together another exciting programme for 2017. Along with plenty of case studies from companies that have been through the process themselves, the programme will include sessions on collaborating and funding, which are key topics in the sector today, alongside ample opportunities for networking throughout the day. We are pleased to announce that Sharon Vosmek, CEO of Astia (a US investor powerhouse) will be joining us from the US to deliver one of the keynote addresses at ON Helix 2017. For the first time at ON Helix, we will be holding a joint investors’ dinner with Cambridge Enterprise the evening before ON Helix, as well as holding our Summer BioNewsRound Award Finals and Welcome Reception at the EMBL‑EBI. With plenty of time to network, opportunity to take part in 1‑2‑1 partnering meetings, 30 plus exhibitors and many other inspirational speakers, ON Helix promises to be another great event for 2017.

Save the date for 2018: ON Helix, 17 July 2018 l For more information about ON Helix, please contact Nadia at nadia@onenucleus.com or visit www.onhelix.com.

Past delegates say it best... Good translational research is vital if we are to address patient needs in an expert way long into the future. ON Helix brings together people who have been there and done it successfully. It is a great way for companies to hear best practice and to find out how to do things more quickly, less expensively and in a more timely way. Professor Sir John Savill, CEO, MRC ON Helix is THE translational event in the UK where all participants can expect to network at the highest level with each other and learn an incredible amount all in the one day. It’s terrific! Sir Mike Rawlins, Former Chair of Eastern AHSN, President of the Royal Society of Medicine, now Chair of MHRA The ON Helix conference stimulated imaginative debate about how we can translate discovery and invention in the life sciences into innovation in medicines and diagnostics, with the real prospect of impact on the health and wealth of the population. I can’t wait for the next event! Professor Nick Lemoine, Medical Director, NIHR Congratulations on organising such an actively attended and enriching meeting. Alan Hirzel, CEO, Abcam

20 | One Nucleus Directory 2017


Space now available on new 25 acre Science Park

Innovation starts here

© Scott Brownrigg Ltd

Figured dimensions only are to be tak this drawing. All dimensions are to be on site before any work is put in hand

Layout Sign Off Client Approved :

Date :

• Superb location on M11 between London and Cambridge • Planning consent in place

PLOT B

PLOT C

PLOT T

PLOT X PLOT E

• Business rate discounts available for five years

PLOT D

PLOT W

PLOT Y

PLOT V1 + V2

PLOT F

PLOT G

PLOT S

• Superfast broadband PLOT R

PLOT H

PLOT Q

PLOT J PLOT I

S

PLOT K

PLOT M

P

I N

E

R

O

A

D

PLOT L

PLOT N

PLOT P

PLOT Z

security

PLOT O

-

-

20 Oc 2016

Rev

Description

Date

St. C 46-48 Guild GU2 T +4 W ww

Client's name

Vinci Development Harlow District Cou Job Title

Harlow Science Pa Drawing Title

Masterplan Layout

Scale

1:1000 @ A0 Over Job No.

Drawing No.

16444

MP001

Status

For Information

Andrew Bramidge, Enterprise Zone Project Director: e: andrew.bramidge@harlow.gov.uk t: +44 (0)1279 446410 m: +44 (0)7890 756438 w: harlowez.org.uk • www.harlowsciencepark.co.uk @HarlowEZ • @Harlow_SP


Dates for your Diary

Dates for your Diary

ken from e checked d.

FEB

Network Meeting Barclays Eagle Labs, Cambridge

18

JUN

One Nucleus BIO Executives Dinner San Diego, USA

MAR

BioWednesday Queen Mary BioEnterprises, London

19

JUN

One Nucleus BIO Breakfast Seminar San Diego, USA

MAR

Leadership Seminar Norwich Research Park, Norwich

05

JUL

BioWednesday King’s College London

MAR

Business Intelligence Breakfast Penningtons Manches, Cambridge

12

JUL

ON Helix Welcome Reception EMBL‑EBI, Cambridge

MAR

Business Intelligence Breakfast Boult Wade Tennant, Cambridge

JUL

13

ON Helix Wellcome Genome Campus Conference Centre, Cambridge

MAR

Business Intelligence Breakfast Boult Wade Tennant, London

SEP

BioWednesday Gowling WLG, London

APR

BioWednesday EIP, London

SEP

Network Meeting Deloitte, Cambridge

APR

Leadership Seminar London

OCT

BioWednesday Queen Mary BioEnterprises, London

APR

Network Meeting Taylor Vinters, Cambridge

OCT

Leadership Seminar Cambridge

APR

Innovation Seminar Cambridge

OCT

M11 Health Enterprise Forum Harlow

MAY

BioWednesday Marsh, London

OCT

Network Meeting Mills & Reeve, Cambridge

MAY

Network Meeting Marks & Clerk, Cambridge

NOV

BioWednesday London

JUN

BioWednesday LBIC, London

NOV

Leadership Seminar Cambridge

JUN

Business Intelligence Breakfast Penningtons Manches, Cambridge

NOV

Network Meeting Stevenage Bioscience Catalyst, Stevenage

JUN

Network Meeting - Summer Social Chesterford Research Park, Cambridge

DEC

Genesis Welcome Reception London

JUN

M11 Health Enterprise Forum Harlow

DEC

Genesis QEII Centre, London

22 01 02 07 08 15 05 25 26 27

ct 6

MG

BC

e

Drawn

Checked

03

Catherine's Court 8 Portsmouth Road dford 2 4DU 44 (0)1438 568686 ww.scottbrownrigg.com

ts UK Ltd uncil

17

ark

07

rsize

.

06 20 04 10

11 18

01 15

Rev.

-

13 14 15

22

13 14

www.onenucleus.com | 23


Purchasing Scheme

Purchasing Scheme The One Nucleus Purchasing Scheme has been running since 2000 with an annual turnover exceeding £7 million and with more than 100 members. It is the longest running purchasing consortium of its kind in the UK, saving members over £4 million per annum. The Purchasing Scheme is directed by the Gold Members and delivers substantial cost savings to Purchasing Scheme Members with the vast majority of member companies saving more than their annual membership fee. One Nucleus currently has ten Preferred Supplier Agreements (PSAs) in place who undergo a rigorous tender process and are selected, not by One Nucleus, but by the Purchasing Scheme Members. These deals are only available to One Nucleus Gold Members. They are: l Air Liquide – laboratory gases l Air Products – liquid nitrogen services l BOC – liquid nitrogen and dry ice services l Deliver Plus – courier services l Fisher Scientific – laboratory consumables, laboratory chemicals and low value apparatus l Flight Centre Business Travel – business travel services l GE Healthcare – servicing and maintenance of laboratory equipment l Harts Business Solutions – stationery, office goods, IT consumables and office furniture l Sigma‑Aldrich – life science products l STARLAB – pipette maintenance and calibration services One Nucleus can perform a cost‑benefit analysis for Silver Members thinking of upgrading to Gold membership (and therefore gaining access to PSAs) or companies wanting to become Gold Members. For more information, please contact Richard Dickinson on 01223 896 453 or at richard@onenucleus.com. One Nucleus also offers Support Supply Agreements (SSAs) that are available to ALL members. If sufficient interest is generated by an SSA, then the contract will be considered for upgrading to PSA status (following the tender process). The list continues to grow year on year. Company

SSA

Contact information

001 Ltd

Business gas and electricity cost reductions

John Hamshere john.hamshere@001ltd.co.uk, 0845 389 2001

A4PBIO

Bioanalytical services and logistical Scott Vincent solutions scott.vincent@a4pbio.com, 01304 249 107

Amphora Research Systems

Electronic laboratory note books

hello@amphora‑research.com, 0845 230 0160

Bioline Reagents Ltd

Specialised bio‑research reagents

Miles Collier miles.collier@bioline.com, 07941 106 618

Black Swan Analysis

Business analysis and marketing support services

Christopher Ehinger christopher.ehinger@blackswan‑analysis.co.uk, 01628 621 790

Cambridge Relocations Ltd

Relocation services in Cambridge

enquiries@cambridgerelocations.co.uk, 01223 573 595

24 | One Nucleus Directory 2017


Purchasing Scheme

Company

SSA

Contact information

Cambridge Research Biochemicals

Custom‑made peptides and antibodies

Emily Humphrys emily.humphrys@crbdiscovery.com, 01642 567 180

DoubleTree by Hilton Cambridge

Hotel and conference accommodation

Avril Farr avril.farr@hilton.com, 01223 259 988

First Sight Media

Multimedia production services and web communications

Paul Starsky paulstarsky@firstsightmedia.co.uk, 0800 072 8753

FluidX

2D bar‑coded sample storage systems; liquid handling/sealing equipment and consumables

Emma Ryan emma.ryan@fluidx.co.uk, 07796 303 277

Fluorochem

Chemical intermediates

Lee Jones leej@fluorochem.co.uk, 01457 860 111

Gilson UK Ltd

Liquid chromatography, solid phase extraction, liquid handling and gel permeation chromatography equipment

Susanna Lovell slovell@gilsonuk.com, 07771 580 815

Grundon Waste Management Ltd

Specialist waste removal

Becky Lilly‑White clinical@grundon.com, 01628 501 591

Haseltine Lake LLP

Intellectual property services

David Hammond dhammond@haseltinelake.com, 0117 910 3200

Hilton Cambridge City Centre Hotel and conference accommodation

Avril Farr avril.farr@hilton.com, 01223 259 988

Hyper Recruitment Solutions (HRS)

Recruitment services

Ricky Martin ricky.martin@hyperec.com, 020 3225 5120

Kinesis

Chromatography products and services

Angelica Chhiba angelicac@kinesis.co.uk, 01480 479 957

KISS Communications

Integrated marketing services

Simon Fryer info@kisscom.co.uk, 020 8123 4575

Labmode Ltd

Biobanking sample storage facilities

David Woodley david.woodley@labmode.co.uk, 07825 711 987

Labstract

Analytical services and training

Suki Klair suki.klair@labstract.co.uk, 0870 803 2491

La Playa

Commercial insurance

Hanna Beaumont hanna.beaumont@laplayainsurance.com, 01223 200 667

La Playa

Employee benefits and financial services

Hanna Beaumont hanna.beaumont@laplayainsurance.com, 01223 200 667

La Playa

Pensions

Henry Metcalf henry.metcalf@laplayainsurance.com, 01223 200 650

La Playa

Personal insurance

Matthew Mullee matthew.mullee@laplayainsurance.com, 01223 200 652

Continued overleaf www.onenucleus.com | 25


Purchasing Scheme

Purchasing Scheme continued Company

SSA

Contact information

Liquidity Services UK Limited

Redundant asset management services

Jonathan Saville jonathan.saville@liquidityservices.com, 07774 652 404

M Files

Quality management software

Rob Swan rob.swan@m‑files.com, 07557 119 128

MAP Biopharma

Market access services

Christian Hill christian@mapbiopharma.com, 01480 832 360

Money Movers

Foreign exchange and global payments

Amanda Nunn amanda@moneymover.com, 01223 928 037

Quality Care Cleaning Services

Commercial cleaning services

Paul Heales paul@qualitycarecleaning.co.uk, 01223 833 300

RiverRhee Consulting

Team and process development and training

Elisabeth Goodman info@riverrhee.com, 07876 130 817

S‑Tech Insurance Services Ltd

Commercial insurance

Dick Culpin dickc@s‑tech.co.uk, 01223 445 439

S‑Tech Insurance Services Ltd

Credit insurance

Adrian Cooper adrianc@s‑tech.co.uk, 01223 445 428

SRG

Recruitment

Richard Acton richard.acton@srg.co.uk, 07876 038 813

Strem Chemicals UK Ltd

High purity chemicals and speciality materials

Debora or Nigel enquiries@strem.co.uk, 0845 643 7263

Tier 2 Consulting

Software for compliant environment

Chris Ellis cellis@tier2consulting.com, 01438 310 124

Are you looking for space as a start-up or for grow-on space? One Nucleus provides project management for all your laboratory fit-outs. •

Setting up of laboratory equipment service contracts

Cleaning contracts

Building maintenance contracts

Utilities

Insurance

Budgeting

Purchasing

Contact: richard@onenucleus.com

26 | One Nucleus Directory 2017

Tel: 01223 896453


Facilities Management and Health and Safety Services

Facilities Management and Health and Safety Services Facilities management can be a real problem for small technology companies with exacting demands for laboratory, workshop and office space. Are you aware that One Nucleus provides a range of Facilities Management Services to help our member companies to expand or relocate? We can provide project management for office and laboratory fit‑outs (no job too small) and can help with laboratory service contracts, maintenance contracts, cleaning contracts, utility bills, insurance, purchasing and budgeting. As with all One Nucleus services, these are provided at discounted rates to members. Our Facilities Management Services and Purchasing Scheme are managed by Richard Dickinson, One Nucleus’ Director of Specialist Services, who has more than 20 years’ experience in laboratory and facilities management. Richard has worked with many One Nucleus members on various projects: Abzena, Inivata, Econic Technologies, Pathology Diagnostics, Cantab Biopharmaceuticals, Fahy Gurteen Laboratories, Spirogen, Origin Sciences, Babraham Bioscience Technologies, Iontas, Agenus, Aqdot and Astex. Richard, who is NEBOSH certified in health and safety, has extensive local contacts in the Cambridge area and can provide help by phone or email as well as providing full on‑site consultancy. Health and Safety Services One Nucleus also provides health and safety consultancy to members at a discounted rate and provides support for health and safety policy development, training and audits. Sara Cooper, Director of SJC Safety Training and Consulting and former Director of Health and Safety at the University of Cambridge, is One Nucleus’ principal health and safety consultant. She has worked on expert committees in the UK and for the EC, and for international clients setting up specialist facilities, including the design and operation of safety‑critical laboratories. During 20 years as a safety professional she has focused on safety auditing, management training and promoting safety at director level. She is a Fellow of IOSH, a Chartered Safety Practitioner, a Member of the Royal Society of Chemistry and an ISTR Biosafety Professional (Level 2). Please contact Richard on 01223 896 453 or at richard@onenucleus.com if you have any questions about One Nucleus’ Facilities Management or Health and Safety Services.

www.onenucleus.com | 27


Training Courses

Training Courses One Nucleus is dedicated to providing bespoke training and support to the life science and healthcare sector through a comprehensive portfolio of industry‑specific training courses. One Nucleus recognises that a company’s employees are its most valuable asset. Many rapidly growing companies overlook the need for ongoing training of their staff. We have developed a tailored portfolio of training courses based on the needs of our member companies. Our current range of courses includes: l A BioSafety Masterclass: Building and Maintaining Competence in BioSafety l Biological Safety: Management and Practice (IOSH accredited) l H&S for Committee Members and Representatives l Introduction to Managing Life Science Projects l Introduction to Managing Alliances and Partnerships l Introduction to Contracts l Introduction to Drug Development, for Scientific and Non‑Scientific professionals l Introduction to Drug Discovery – From Idea to Clinical Candidate l Laboratory Health and Safety l Presentation Skills for Scientists l The Safe Use and Management of Laboratory Gases

We are also able to offer a range of softer skills courses through our network of training providers, including: l Supervisor Training l Confident Communications l Managing Work Time and Pressure l Practical Stress Management l Negotiation Skills l Networking Skills l Presentation Skills l The First Steps in Selling l Writing for Business and Science

28 | One Nucleus Directory 2017

One Nucleus Silver Members receive a discount from the list price and Gold Members receive increased discounts on the list price plus priority booking.

Working in partnership with Pharmaceutical Training International (PTI)

We are constantly developing courses on new subjects as our members’ needs change. With this in mind, we are now pleased to offer our training courses in London as well as Cambridge.

PTI and One Nucleus have come together to form a new partnership – offering One Nucleus members exclusive access to the PTI library of industry podcasts and special discounts when booking onto PTI training courses. Between the portfolios of One Nucleus and Pharma Training International, members can access discounts on over 80 tailored training courses covering the breadth of the life science industry as follows:

Do remember, all of these courses can be delivered in‑house, tailored and/or combined to create a bespoke training package that meets the exact needs of your organisation.

In‑house courses – let us bring the training to you One area that has continued to grow in popularity is the development of our in‑house offering. This is where we tailor the training to suit your company and bring the course to you. This way, we can train 8‑12 of your staff on your own premises, saving you time and travel expenses. Please let us know if you would like to discuss this in more detail. Delegate Feedback: “Good content and very well delivered” “Hands on course – team work exercises were very good” “A lot of complex topics were covered in an easily digestible manner” “Good speaker with industry knowledge”

l Regulatory affairs l Research and development l Health and safety l Clinical development l Biopharmaceuticals l Fine chemicals l Medical devices l Generics l Animal health l Agrochemicals l Manufacturing l Softer skills including powerful presentations, project management, negotiation and communication.

For more information about the PTI training portfolio, and how you can receive a 25% discount, please visit our website: www.onenucleus.com/training. Please contact Claire or Richard on 01223 896 450 or training@onenucleus.com if you have any questions about the One Nucleus Training portfolio.


Special Interest Groups (SIGs)

Special Interest Groups (SIGs) Special Interest Groups are typically run four times a year and are a Gold Member benefit. HR Any Gold Member of One Nucleus who deals with personnel issues is welcome to attend meetings of the HR SIG, whether you’re an experienced HR professional, just learning the ropes or only get involved because there’s no one else to do it! The group meets regularly throughout the year for a series of informal and proactive workshops and seminars on HR topics directly relevant to the biomedical sector. The sessions are run by Eleanor Freeman, a partner at Cambridge Employment Law LLP. The events offer the opportunity to learn, network and share best practice in a ‘safe’ environment. Eleanor also provides a newsletter updating you on the changes to employment law that you need to know and highlights issues relevant to the biomedical sector. Cambridge Employment Law LLP is a specialist employment law practice, advising both employers and employees. Eleanor Freeman has particular experience advising the biomedical sector. Find out more at: www.cambridgeemploymentlaw.com.

Health and Safety The aim of the Health and Safety SIG is to provide a platform of communication for health and safety managers. These meetings were developed at the request of health and safety managers who wished to meet with their industry peers. Topics cover: Spill procedures, COSHH, GMOs, legislative updates and the overview of the challenges facing health and safety managers. * One Nucleus reserves the right to exclude individual members from individual SIGs where we consider there to be a conflict of interests.

Findacure is a UK charity that is building the rare disease community to drive research and develop treatments. We work to: 1. Empower patient groups to build their patient community, develop as a charity, and drive treatment research and development. 2. Promote collaboration between rare disease stakeholders to facilitate treatment development for all.

One Nucleus Charity of the Year 2017 www.findacure.org.uk | Tel: +44 (0)1223 222767

www.onenucleus.com | 29


ON Hub

ON Hub: for life science executives on the road At the heart of what we do at One Nucleus is bringing the right people together and creating the right services and environment in which to do business. With ON Hub, members can take advantage of the domestic and international collaborations One Nucleus maintains in order to assist our members in maximising the effectiveness of their activities. This One Nucleus initiative links a number of life science hubs, global accommodation providers, significant savings on flights and connections through One Nucleus international counterparts in order to: l Access a variety of services, such as WiFi, informal meeting spaces, refreshments and private meeting rooms at a variety of life science hubs across the UK when visiting regions remote from their office. Participating Hubs are listed on the One Nucleus website and include sites in Cambridge, London, Welwyn Garden City, Cardiff and Manchester thus far, and the list is growing l Simplify global accommodation and business meeting needs by registering with the loyalty schemes offered by our collaborators at Hilton Hotels and Club Carlson l Maximise the savings and support whilst flying long haul for major conferences or day‑to‑day travel via our partner travel management company at Flight Centre Business Travel (FCBT). Based out of its Cambridge office, FCBT undertakes to provide One Nucleus members with the lowest price available on the member’s bespoke itinerary, leaving choice of airline, hotel and departure airport entirely in the hands of the travelling executive. Furthermore, FCBT pre‑negotiates great deals on selected flights and hotels around major international conferences such as BIO, Biopharm America and J P Morgan

For more information on ON Hub, please contact Tony at tony@onenucleus.com.

30 | One Nucleus Directory 2017

l Leverage our One Nucleus relationships with like‑minded regional contacts across Europe, North America and Asia in order to secure accurate market intelligence, contacts and orientation within a target market when seeking partners, investors or routes to market. These connections include: - Our MOU partners, BIOCOM, California Life Sciences Association, MassBIO and MassMEDIC on the East and West Coast US as well as additional US and Canadian collaborators including BioNJ, Pennsylvania Bio and Life Sciences British Columbia - European cluster groups from hubs including Medicon Valley, Stockholm – Uppsala, Munich, Heidelberg, Paris and Barcelona - Connections with Asia Pacific groups including Queensland Life Sciences, Japanese Biotech Association and KHIDI in Korea - Discounted conference attendance, often in collaboration with BioPartnerUK and EBD Group for events such as Biotech Showcase. Numerous other conference discounts also become available through One Nucleus relationships with third party organisers throughout the year - Collaboration with the Department for International Trade (DIT) and overseas Embassies in London where appropriate in order to keep our members abreast of engagement opportunities


European Activities

European Activities One Nucleus’ mission is to maximise the global growth and competitiveness of our members. One of the key strands of our strategy is our international activities and we encourage our members to take advantage of platforms and initiatives we work on in this regard. We recognise that for UK companies to be strong, they need to have access to and relations with other exceptional global companies. The sector is global and the success of it hangs on us working in partnership with relevant international organisations for mutual benefit. This is why One Nucleus has always had an interest in being involved in European activities, encouraging members to take advantage of initiatives and platforms we work with and on. This engagement is also a great opportunity for One Nucleus to develop even closer connections with other European bioregions and to improve our knowledge of the sector outside the UK. As some of you will be aware, we collaborate each year at BIO with other European clusters on joint activities for our members and theirs – in particular the One Nucleus BIO Breakfast that, since 2012, has seen us working with Stockholm‑Uppsala Life Science as well as the major US cluster organisations. We are in regular discussions with all the major European clusters regarding ongoing information exchanges, visits and collaborations for tangible member benefit and, of course, many are involved in our annual Genesis Conference. Do let us know if you would like us to introduce you to European cluster organisations/managers. We know them all! One Nucleus is also a member of, and strongly involved in the Council of European BioRegions (CEBR), which is the biggest and most active network of bioclusters in Europe. www.lifescience‑cluster‑innovations.space. Harriet, our Chief Executive, is actively involved in CEBR too, supporting the organisation’s strategy and future, and as a member we attend the AGM each year, which is a fantastic opportunity to reinforce our good connections with the main European bioregions. For more information on One Nucleus’ European activities, please contact Aline at aline@onenucleus.com.

13 July 2017 Cambridge, UK

Translating UK scientific excellence into global therapeutic strategies

www.onenucleus.com | 31


Strategic Relations with Top US Clusters

Strategic Relations with Top US Clusters One Nucleus members have expressed a desire for us to develop strategic partnerships with other leading clusters (specifically in the US) and to provide members with access to potential partners and investors from other global centres of excellence. With this in mind, we have signed four separate Memoranda of Understanding (MOU) with top US clusters organisations: MassBIO, MassMEDIC, BIOCOM and CLSA. In October 2009 we signed our first Memorandum of Understanding (MOU) with MassBIO to encourage and promote co‑operation and deal flow between members. The MOU confirmed a commitment to facilitate transatlantic investment and partnering by encouraging collaborations between each group’s member companies. One Nucleus and MassBIO now promote each other’s investment and partnering events, offering members reduced rates and speaking opportunities. Importantly, and as a direct result of the formal relationships, One Nucleus members can also benefit from being offered a ‘soft landing’ by the US cluster organisation when members are looking to set up, do business or identify potential partners or investors on the East and West Coast US. A second MOU was signed in December 2009 with the Massachusetts Medical Device Industry Council (MassMEDIC) to actively encourage co‑operation and collaboration between UK and US companies in the medical device sector. Subsequently, we signed a third MOU with Joe Panetta of BIOCOM (the cluster group in San Diego and Los Angeles) at BIO 2010 and a fourth MOU was signed with Gail Maderis, President of CLSA (the cluster group in San Francisco) at Genesis in December 2010. We are delighted that these strong relationships have led to tangible outcomes for One Nucleus and US partner members so far. These include: l A great BIO Executives Dinner hosted by One Nucleus at BIO each year, tailored to the interests of members, with a further one planned at BIO 2017 l A hugely well‑received Business Breakfast at BIO each year, hosted by One Nucleus and Stockholm-Uppsala Life Science, with collaboration from CLSA and BIOCOM and a further one planned at BIO 2017 l One Nucleus being asked to host the visit to the UK of the Governor of Massachusetts – to create a platform for him to deliver his keynote address on life sciences, which we were proud and delighted to arrange l One Nucleus hosting the life sciences element of the UK visit of the Governor of New Jersey in February 2015 l We negotiate specific packages of support for our members on an ongoing basis for the major US cluster events l The President of the Mass LifeScience Center, Susan Windham‑Bannister, as a keynote speaker for one of our Leadership Series events and subsequently (in her new role) as a Keynote Speaker at ON Helix 2016 l Ongoing strong and collaborative support between One Nucleus and the four MOU partners, including continuing profiling of each other’s organisations and members in‑market l Strategic partnerships signed with BioNJ, Pennsylvania Life Sciences and Life Sciences British Columbia in 2015

Harriet Fear CEO, One Nucleus 32 | One Nucleus Directory 2017


One Nucleus Collaborations

One Nucleus Collaborations One of the clear messages I receive regularly from members is a request to work collaboratively with other organisations and cut down the duplication of efforts in the UK. This feedback has helped us carve out our strategy and this, combined with a request from members to create connections with international organisations who can help our members grow, is at the heart of what we stand for. A clear recognition of the above was the formal merger of ERBI and London Biotechnology Network in May 2010. We also, of course, have our four Memoranda of Understanding in place with CLSA, MassBIO, MassMEDIC and BIOCOM in the USA. The spirit of partnership is very strong in the One Nucleus team, and we continue to enhance our offer for members, with partnerships with other organisations. These include: l Our Partner Programme with AstraZeneca, Babraham Bioscience Technologies, BioMed Realty, Deloitte, EBD Group, Eli Lilly, First Sight Media, Flight Centre Business Travel, GlobalData, Global Regulatory Services (GRS), Hume Brophy, London Bioscience Innovation Centre, MSD, Norwich Research Park, Penningtons Manches, Pharmaceutical Training International, PharmaVentures, PPD, Queen Mary BioEnterprises, SCRIP Intelligence, Stevenage BioScience Catalyst, The Assay Depot, and Wellcome Trust Sanger Institute l Collaboration with the Licensing Executive Society (LES) for member benefit l Formal supporter of the ‘Case for Cambridge’ via Cambridge Ahead l Local collaboration in Cambridge with Cambridge Wireless (CW), e.g. we hosted a joint event with them in September 2012 and November 2014 on the convergence of healthcare and IT, and CW worked closely in association with us on a stream at Genesis 2016 – Digital Health l Working with Cambridge Wireless, Cambridge Network and Cambridge Cleantech, our four organisations strongly support and deliver Cambridge Awards Week each year in collaboration with Cambridge News, Real VNC and Business Weekly. Importantly, in 2014 we launched (and were a founding member of ) United Life Sciences with the BIA, Bionow and BioPartner UK. This is our informal collaboration between like-minded membership organisations in the UK. It has seen us working together on the creation of a set of BioMedical Catalyst Fund handbooks and the Life Science Manifesto 2015‑2020, which informed political parties of the needs of our members and the sector into the long‑term future. MediWales joined us in 2015. We also have deals in place with other international organisations for member benefit, for example EBD Group. Do contact us for more information on the above, or if there is an organisation you would like to see us work with, let us know. We may already have a ‘deal’ in place with them!

Harriet Fear CEO, One Nucleus

www.onenucleus.com | 33


When:

Monday 30 October 2017 10.30am to 7:30pm

Where:

EMBL-EBI, Kendrew Lecture theatre South Building, Wellcome Genome Campus, Hinxton, Cambridge CB10 1SD

What:

A day of networking opportunities and presentations about how your company can make the most of public molecular data and services.


One Nucleus

Corporate Patron and Corporate Sponsors


Corporate Patron and Corporate Sponsors

Amgen Limited Cambridge Science Park, Milton Road, Cambridge CB4 0WD, UK Tel: 01223 420 305 Fax: 01223 426 314 Email: ukcorporate.affairs@amgen.com Website: www.amgen.co.uk

Amgen works to unlock the potential of biology for patients suffering from serious illnesses by discovering, developing, manufacturing and delivering innovative human therapeutics. Beginning with tools like advanced human genetics, Amgen unravels the complexities of disease to understand fundamental human biology. With a focus on areas of high unmet medical need and leveraging biologics manufacturing expertise, Amgen aims for solutions that significantly improve health outcomes. A biotechnology pioneer since 1980, Amgen has grown to be the world’s largest independent biotechnology company, has reached millions of patients around the world and is developing a pipeline of medicines with breakaway potential.

Chesterford Research Park Little Chesterford CB10 1XL, UK Tel: 01799 532 252 Email: km.chesterfordrp@btconnect.com Website: www.chesterfordresearchpark.com Contact: Katherine Maguire

Building on 60 years of continuous R&D at Chesterford, the Park is now home to innovative biotechs and pharmaceutical companies such as Arecor, AstraZeneca, Diagnostics for the Real World and Domainex, a community that has amassed an impressive record for producing cutting‑edge technology and groundbreaking scientific discoveries. Underpinning these successes, our Park environment offers a flexible range of accommodation, ideally suited to companies at all stages of development and a highly supportive Park team, who truly understand occupiers’ objectives. Set within 250 acres of idyllic parkland near Cambridge, the low density development at Chesterford is ideally positioned to further occupiers’ success.

Johnson & Johnson Innovation 1 Chapel Place, London W1G 0BG, UK Tel: 020 7573 4500 Website: www.jnj.com

36 | One Nucleus Directory 2017

Johnson & Johnson Innovation, Ltd focuses on accelerating early‑stage innovation worldwide and forming collaborations between entrepreneurs and Johnson & Johnson’s global healthcare businesses. Johnson & Johnson Innovation provides scientists, entrepreneurs and emerging companies one‑stop access to science and technology experts who can facilitate collaborations across the pharmaceutical, medical device and consumer companies of Johnson & Johnson. Johnson & Johnson Innovation includes local deal‑making capabilities with the flexibility to adapt deal structures to match early‑stage opportunities and establish novel collaborations that speed development of innovations to solve unmet needs in patients. Make the connection with us, please visit www.jnjinnovation.com. @JNJInnovation.


Corporate Patron and Corporate Sponsors

MedImmune Limited Milstein Building, Granta Park, Cambridge CB21 6GH, UK Tel: 01223 471 471 Fax: 01223 471 472 Email: elvinj@medimmune.com Website: www.medimmune.com Contact: John Elvin

MedImmune is the global biologics research and development arm of AstraZeneca with candidate biologics and vaccines that currently comprise approximately 50 per cent of AstraZeneca’s overall R&D pipeline. It has one of the most robust and promising pipelines in the biologics industry, with more than 120 biologics in research and development and over 40 projects in clinical stage development. MedImmune is pioneering innovative research and exploring novel pathways across key therapeutic areas, including oncology, respiratory, and cardiovascular and metabolic disease. In addition, the company is opportunistic in infectious disease and vaccines. MedImmune’s Cambridge team is focused on the research and early development of our biologics portfolio.

Roche Shire Park, 6 Falcon Way, Welwyn Garden City, Hertfordshire AL7 1TW, UK Email: andrew.armes@roche.com Website: www.roche.com Contact: Andrew Armes

With almost 2000 employees in the UK, based predominantly in Welwyn Garden City in Hertfordshire and Burgess Hill in West Sussex, and over 90,000 employees globally in 150 countries, we are the world’s largest biotech company. In the UK we spent £580 million in 2015, 60 per cent on clinical development, 33 per cent on non‑clinical investment spend, and 7 per cent on sales and marketing. We have over 20 UK partnerships with leading academic institutions and universities including Genomics England and the National Institute for Health Research and we have eight current joint working partnerships with the NHS.

Taylor Wessing 24 Hills Road, Cambridge CB2 1JP, UK Tel: 01223 446 422 Fax: 020 7300 7100 Email: m.bates@taylorwessing.com Website: www.taylorwessing.com Contact: Dr Malcolm Bates

Taylor Wessing LLP has offices in London and Cambridge and is a leading international law firm with 27 offices in Europe, the USA, the Middle East and Asia. We advise life science businesses, those who fund them and those who work for them. Our extensive Life Sciences Group combines lawyers from Taylor Wessing’s intellectual property, corporate, competition, dispute resolution and employment practices. The Group in the UK includes 15 lawyers with first degrees in life sciences subjects, of whom several have PhDs and many have spent periods working in the biotech and pharmaceutical industry.

www.onenucleus.com | 37


One Nucleus

Partners


Partners A|D

AstraZeneca Academy House, 136 Hills Road, Cambridge CB2 8PA, UK Tel: 020 7604 8000 Email: ayesha.bharmal@astrazeneca.com Website: www.astrazeneca.com Contact: Ayesha Bharmal

AstraZeneca is a global, science‑led biopharmaceutical company that focuses on the discovery, development and commercialisation of prescription medicines, primarily for the treatment of diseases in three main therapy areas – oncology, cardiovascular and metabolic diseases and respiratory. The company is also selectively active in the areas of autoimmunity, neuroscience and infection. AstraZeneca operates in over 100 countries and its innovative medicines are used by millions of patients worldwide. For more information, please visit www.astrazeneca.com

Babraham Bioscience Technologies Ltd Babraham Research Campus, Cambridge CB22 3AT, UK Tel: 01223 496 269 Email: info@babraham.co.uk Website: www.babraham.com Contact: Derek Jones

Babraham Bioscience Technologies (BBT) is the company that manages and develops the Babraham Research Campus, supporting and promoting the regional and UK bioscience ecosystem. The campus is home to over 60 companies, co‑located with the Babraham Institute, and is considered to be the UK’s leading campus supporting early stage bioscience enterprises. The campus offers bespoke, state‑of‑the‑art research and development facilities, scientific support services for bio‑ventures and a supportive and well networked community at the heart of the Cambridge life science cluster. BBT manages the newly constructed conferencing facility, offering a premier venue for up to 300 people.

BioMed Realty Trust Inc McClintock Building, Granta Park, Great Abington, Cambridge CB21 6GP, UK Tel: 01223 893 710 Email: doug.cuff@biomedrealty.com Website: www.biomedrealty.com Contact: Douglass Cuff

BioMed Realty is the leading provider of real estate solutions to the life science community. With over 14 million square feet of rentable space worldwide, the company has a proven track record in bringing unmatched expertise to the full range of real estate services – leasing, development, construction, redevelopment, acquisition, financing and property management – to our tenant partners in the USA and UK.

Deloitte Deloitte House, Station Place, Cambridge CB1 2FP, UK Tel: 01223 460 222 Fax: 01223 350 839 Email: lwelham@deloitte.co.uk Website: www.deloitte.co.uk Contact: Lee Welham

40 | One Nucleus Directory 2017

The Deloitte Life Sciences and Healthcare practice supports companies within the pharmaceutical, biotechnology, medical devices and healthcare sectors with the key challenges they face in today’s changing global landscape. We are passionate about our industry and endeavour to bring insight and innovation to support our clients in the role they play in driving better patient outcomes, sustaining a strong health economy and enhancing the reputation of the industry.


Partners E|F

EBD Group Baarerstrasse 139, CH‑6300 Zug, Switzerland Tel: +1 760 930 0500 Email: mhildebrand@ebdgroup.com Website: www.ebdgroup.com Contact: Erin Righetti

EBD Group is the leading partnering firm for the global life science industry. We are experts in bringing people together. Our comprehensive partnering solution incorporates conferences, software and services that drive a highly productive and efficient partnering process for thousands of industry dealmakers worldwide. EBD Group’s sophisticated web‑based partnering service, partneringONE®, is used as the partnering engine at numerous third party events around the world, and partnering360® is the open online community of life science dealmakers that enhances partnering experiences throughout the year. For more information go to www.ebdgroup.com, or join the over 37,000 dealmakers on partnering360 at www.partnering360.com.

Eli Lilly and Co Erl Wood Manor, Sunninghill Road, Windlesham GU20 6PH, UK Tel: 01276 483 454 Email: lawford_kerri@network.lilly.com Website: www.lilly.com Contact: Kerri Lawford

Since Eli Lilly and Company was founded more than 140 years ago, our mission has remained unchanged: create high‑quality medicines that make life better. Healthcare challenges are complex and the unmet need is great; we know we can’t do it alone. We must be innovative in our science and in our approach to partnerships to bring medicines to the people who need them. Our greatest interests include: oncology, neurodegeneration, pain, diabetes, immunology, cardiovascular, drug delivery and devices. We are passionate about engaging in innovative partnerships in any of these areas.

Findacure: The Fundamental Diseases Partnership 66 Devonshire Road, Cambridge CB1 2BL, UK Tel: 01223 222 767 Email: info@findacure.org.uk Website: www.findacure.org.uk

Findacure is a UK charity that is building the rare disease community to drive research and develop treatments. We work to: 1) Empower patient groups to build their patient community, develop as a charity and drive research; 2) Promote collaboration between rare disease stakeholders to facilitate treatment development for all.

First Sight Media Suite 3‑5, Wesley House, Ventura Park, Carterton, Oxfordshire OX18 1AD, UK Tel: 01993 847 620 Email: paulstarsky@firstsightmedia.co.uk Website: www.firstsightmedia.co.uk Contact: Paul Starsky

First Sight Media is a video production company that has, for over 20 years, delivered creative live events, training and promotional video productions and, as a result, built up an experienced and dedicated team of media professionals who pride themselves on exceeding client requirements. Online is our forte and we excel at live and on‑demand video streaming. This is enhanced for conferences and webinars through our bespoke presentation software iPresenter, allowing us to deliver a high definition video of a speaker simultaneously with their presentation slides. Our website contains many examples of our work together with testimonials supporting the services we provide.

www.onenucleus.com | 41


Partners F|H

Flight Centre Business Travel 50 Sidney Street, Cambridge CB2 3HX, UK Tel: 01223 301 940 Email: charlie.tulip@flightcentre.co.uk Website: www.flightcentre.co.uk/business‑travel Contact: Charlie Tulip

Since joining One Nucleus in 2011, we have been continually working to offer all its members an unbeatable deal on their business travel. It is our aim to become the number one travel supplier in the biotech industry and to provide all One Nucleus members with the best possible price, service and product available in the market today. We already work with many One Nucleus members. Find out how Flight Centre Business Travel can help you by calling 01223 301 940. We look forward to hearing from you – Charlie Tulip, Business Development Team Leader, Flight Centre Business Travel.

Global Regulatory Services Global House, Painters Lane, Sutton, Ely, Cambridgeshire CB6 2NS, UK Tel: 01223 750 638 Email: greer@globalregulatoryservices.com Website: www.globalregulatoryservices.com Contact: Greer Deal

Operating at the forefront of technology, GRS is an award‑winning specialist organisation with worldwide coverage providing solutions to the global life science industry, focusing on regulatory affairs, quality compliance and innovation. With a worldwide network of professionals, GRS is able to support companies with emerging, novel technologies from foods to herbals, medical devices to IVDs, pharmaceuticals to regenerative therapies and borderline medical products. Specialist teams have been established that have both scientific and regulatory expertise, with the ability to communicate effectively with the regulatory agencies. We continually fulfil our goal of ‘driving innovation to market success™’.

GlobalData John Carpenter House, 7 Carmelite Street, London EC4Y 0BS, UK Tel: 020 7406 6648 Email: smckenzie@globaldata.com Website: https://healthcare.globaldata.com

GlobalData is a one‑stop solution for actionable insight into the pharmaceutical and medical device sectors. Together with the best team of researchers, analysts, epidemiologists and consultants, and an unmatched suite of proprietary databases, we provide high‑quality, accurate and transparent insight that can help you achieve growth and increase business value. Our valuable research and consulting solutions ensure that you stay at the forefront of the industry by integrating accurate market forecasts and healthcare analytics. Our informed healthcare industry perspectives have assisted businesses based across the life sciences in making strategic decisions that have increased the value of their products and services.

Hume Brophy 55 King William Street, London EC4R 9AD, UK Tel: 020 7862 6399 Email: healthcareteam@humebrophy.com Website: www.humebrophy.com Contact: Conor Griffin

42 | One Nucleus Directory 2017

Hume Brophy is an international communications firm specialising in corporate and financial communications for healthcare companies across Europe. Our team of over 80 consultants is based in London, Brussels, Dublin, Paris, Singapore, New York and Boston. Our specialist healthcare team combines global industry knowledge and expertise in public relations, investor relations with government and EU regulatory affairs. We work with private and public clients from over 10 European countries. We have proven transaction expertise and have worked on numerous fund raisings, IPOs and M&A across the sector.


Partners L|P

London BioScience Innovation Centre (LBIC) 2 Royal College Street, London NW1 0NH, UK Tel: 020 7691 1122 Fax: 020 7681 9129 Email: lbic@rvc.ac.uk Website: www.lbic.com Contact: Dr Ken Larkin

Owned by the prestigious Royal Veterinary College (RVC), The London BioScience Innovation Centre (LBIC) is London’s premier incubator for life sciences, providing high quality laboratory space and technical support to over 60 companies. LBIC is located next to the RVC and a short walk from St Pancras International, the Eurostar and the Francis Crick Institute. The RVC provides a range of commercial services via ‘RVC Business’ for biomedical companies looking to access facilities, technical services and academic expertise. Our contract research services cover routine animal husbandry and laboratory services through to full study and design management within regulatory and non‑regulatory environments.

MSD Two Pancras Square, King’s Cross, London N1C 4AG, UK Website: www.msd‑uk.com

Norwich Research Park Norwich Research Park Management Office, Centrum, Norwich Research Park, Norwich NR4 7UG, UK Tel: 01603 673 600 Email: kenny.lang@norwichresearchpark.com Website: www.norwichresearchpark.com Contact: Dr Kenny Lang

Norwich Research Park offers a supportive, innovative environment to science and technology-based businesses, co-located within a unique cluster of four life science research institutes, a university and a teaching hospital. Focused on the needs of science-based businesses, our services include clinical trials facilities, shared laboratories, extensive genomics, proteomics and metabolite services. An enterprise zone location, we offer offices and laboratories on flexible terms, as well as land for development. In addition, we offer shared scientific facilities, business support and access to finance. Less than 20 minutes’ drive from Norwich International Airport, Norwich Research Park is currently home to over 70 businesses and 3000 clinicians.

Penningtons Manches LLP 9400 Garsington Road, Oxford Business Park, Oxford OX4 2HN, UK Tel: 01865 722 106 Email: jim.kinnierwilson@penningtons.co.uk Website: www.penningtons.co.uk Contact: Jim Kinnier Wilson

Our award‑winning life sciences team is led by highly‑ranked lawyers who advise companies in the biotech, pharmaceutical, diagnostics, veterinary and healthcare sectors. We add value with lawyers who understand the science from their degree subjects, and understand your business, having worked in‑house for life science companies, or with them for many years. We act for companies, at all stages of their life cycle, including global pharmaceutical companies, larger plcs and SMEs, together with research organisations, venture capital funds and universities. ‘Impressive IP practice acting for life sciences businesses, universities and their spinoffs… Recommended for licence and research agreements.’ – Chambers 2017.

www.onenucleus.com | 43


Partners P|Q

Pharmaceutical Training International (PTI) Maple House, 149 Tottenham Court Road, London W1T 7AD, UK Email: rachael.ouston@informa.com Website: www.pti‑global.co.uk

Pharmaceutical Training International (PTI) is a global interactive training partner committed to the personal progression of aspiring life science professionals. We provide up‑to‑date and topical courses, addressing the latest concerns facing the pharmaceutical, medical device and biopharmaceutical industries. PTI is dedicated to improving the skills of professionals throughout the life cycle of a product with courses aimed at R&D, regulatory affairs, clinical, manufacturing and business strategy. All of our courses are CPD certified and delivered as public open courses, customised in‑house courses, live webinars and e‑learning courses. We have the flexibility to train teams of all sizes across multiple countries.

PharmaVentures Ltd Triumph House, Parkway Court, John Smith Drive, Oxford Business Park, Oxford, Oxfordshire OX4 2JY, UK Tel: 01865 332 700 Email: enquiries@pharmaventures.com Website: www.pharmaventures.com Contact: Adrian Dawkes

PharmaVentures is a premier transaction advisory firm and a world leader in partnering, M&A deals and strategic alliances. Our bank of specialist experience, deal analytics and network of contacts makes us uniquely placed to support you in all aspects of deal making and strategic planning. PharmaVentures is known for its deep insight into deal structures and success in generating partnering interest. Services include: M&A (divestments, mergers, acquisitions and strategic transactions); strategy (commercialisation, deal strategy, due diligence, market entry); valuation and positioning (licensing, M&A, fundraising and expert testimonies); licensing (in and out licensing); and expert testimony (patent infringement, deal disagreements, taxation, determining damages).

PPD Granta Park, Great Abington, Cambridge CB21 6GQ, UK Tel: 01953 889 301 Website: www.ppdi.com

PPD is a leading global contract research organisation providing drug discovery, development, life cycle management and laboratory services. Our clients and partners include pharmaceutical, biotechnology, medical device, academic and government organisations. With offices in 46 countries and more than 13,000 professionals worldwide, PPD applies innovative technologies, therapeutic expertise and a commitment to quality to help clients and partners accelerate the delivery of safe and effective therapeutics and maximise the returns on their R&D investments. For more information, visit www.ppdi.com.

Queen Mary BioEnterprises Ltd 42 New Road, London E1 2AX, UK Tel: 020 7882 8950 Email: info@qmbioenterprises.com Website: www.qmbioenterprises.com

44 | One Nucleus Directory 2017

QMB is the largest new‑build incubation space in London for companies requiring commercial laboratory space, and accommodates both early and late stage tenants. Accommodation is available in diverse suite sizes from 500ft2 with competitively‑priced leases. The internal fit‑out design means that space can be easily reconfigured to a tenant’s ongoing needs. The QMB management focuses on the physical security, supply chain continuity and electricity security of its tenants.


Partners S|W

SCRIP Intelligence Informa Pharma Healthcare, Christchurch Court, 10‑15 Newgate Street, London EC1A 7AZ, UK Tel: 020 7017 5000 Fax: 020 7017 6985 Email: scrip@informa.com Website: www.scripintelligence.com Contact: Eleanor Malone

SCRIP is a leading source of news and strategic analysis for the global pharmaceutical industry. We filter the flood of information on the industry and apply the knowledge of our extensive network of analysts, journalists and key opinion leaders to provide our readers with timely business critical market and competitor intelligence. For complimentary access to SCRIP Intelligence, visit www.scripintelligence.com/complimentary‑access.

Stevenage Bioscience Catalyst Gunnels Wood Road, Stevenage SG1 2FX, UK Tel: 01438 906 906 Email: info@stevenagecatalyst.com Website: www.stevenagecatalyst.com Contact: Martino Picardo

Stevenage Bioscience Catalyst (SBC) opened as the UK’s first open innovation biomedical campus in 2012, and combines a unique blend of infrastructure and virtual networks to drive collaboration. Backed by a novel partnership between government, GlaxoSmithKline and Wellcome, the remit was, and remains, to catalyse innovation for patient benefit in a phased development. SBC has a strong commitment to companies that focus on high quality science and share its vision, and its development of activity clusters and direct access to the expertise of a major pharmaceutical company are among its unique characteristics.

The Assay Depot Inc 125N. Acacia Ave. Suite 111, Solana Beach, California 92075, USA Email: info@scientist.com Website: www.scientist.com Contact: Dan Kagan

Scientist.com (formerly Assay Depot) is a research marketplace that connects buyers and sellers of research services and products. The marketplace makes it easy for scientists to purchase custom services from thousands of global suppliers who have already agreed to basic contracting terms. With 10 large pharma companies and numerous biotechs using the marketplace, Scientist.com is also a excellent avenue for suppliers to build or expand their global presence. Our mission is to make external research capabilities more accessible to research scientists and, in so doing, dramatically improve how medical research is done.

Wellcome Trust Sanger Institute Wellcome Genome Campus, Hinxton, Cambridge CB10 1SA, UK Tel: 01223 834 244 Email: contact@sanger.ac.uk Website: www.sanger.ac.uk

The Wellcome Trust Sanger Institute is one of the premier centres of genomic discovery and understanding in the world. Our research builds understanding of gene function and genome variation in health and disease as well as creating resources of lasting value to biomedical research. We lead ambitious collaborations across the globe to provide the foundations for further research and transformative innovations in health and beyond. Our success is founded on the expertise and knowledge of our people and we seek to share discoveries and techniques with the next generation of genomic scientists and researchers worldwide.

www.onenucleus.com | 45


Complete contract development and manufacturing services

clinical trials commercial manufacturing wide range of dosage forms focus on orphan drugs

Learn more about APL by visiting our web page www.apl.se

www.asterandbio.com

advantage@asterandbio.com

Discovery Whether you are exploring preclinical drug discovery or companion diagnostics, let our experts in human tissue and research services satisfy your demanding experimental needs

Insulin mRNA (red) Multiplex ISH/IHC

XpressBANK™ Biospecimens

Pro-Insulin Protein (brown)

Normal & Diseased Tissues • Fresh Fixed or Frozen Blood, Serum & Plasma • Synovial Fluid • CSF • TMAs RNA, DNA & Protein • Primary Cells • Proprietary Cell Lines

BioSPOKE™

Custom Biospecimen Procurement

Co-Staining

Negative Control

PhaseZERO® Research Services

Immunohistochemistry • ISH & FISH • LCM Histopathology • Digital Pathology • qRT-PCR • Mutational Analysis OrganDOT™ • Cell Based Assays • 2D & 3D Culture • Primary Cell Isolation


One Nucleus

Gold Members


Gold Members 4

4N GeneHealth Limited Ideaspace, 3 Laundress Lane, Cambridge CB2 1SD, UK Website: www.4ngenehealth.com

Abcam plc 330 Cambridge Science Park, Milton Road, Cambridge CB4 0FL, UK Tel: 01223 696 000 Fax: 01223 215 215 Email: info@abcam.com Website: www.abcam.com

As an innovator in reagents and tools, Abcam’s purpose is to serve life science researchers globally to achieve their mission, faster. Providing the research and clinical communities with tools and scientific support, the company offers highly validated biological binders and assays to address important targets in critical biological pathways. Already a pioneer in data sharing and e-commerce in the life sciences, Abcam’s ambition is to be the most influential company in life sciences by helping advance global understanding of biology and causes of disease, which, in turn, will drive new treatments and improved health. Find out more at www.abcam.com.

Abzena plc Babraham Research Campus, Babraham, Cambridge CB22 3AT, UK Tel: 01223 903 498 Email: info@abzena.com Website: www.abzena.com Contact: Donna Hackett

Abzena offers a range of complementary services and technologies to help companies select, develop and manufacture better biopharmaceuticals. In addition to its headquarters in Cambridge, UK, Abzena has custom synthesis, process development and GMP manufacturing capability in the USA. The services provided in the UK include standard and bespoke immunogenicity assessment, protein engineering, manufacturing cell line development, bioconjugation for antibody drug conjugates and optimisation of pharmacokinetics.

Actigen Limited St John’s Innovation Centre, Cowley Road, Cambridge CB4 0WS, UK Tel: 01223 422 062 Email: info@actigen.com Website: www.actigen.com Contact: Rowena Gardner

48 | One Nucleus Directory 2017

Actigen is building a portfolio of drug candidates focused on immunomodulation as a mechanism of action. Being developed initially as anti‑cancer therapies, which work by re‑awakening the body’s immune system and stimulating the body to attack the cancer, these compounds may also have utility in other diseases. From its base in Cambridge, Actigen’s team of experienced pharmaceutical research and development professionals works together to guide early and later clinical development. Through its global network of academic, scientific and medical experts, Actigen strives to match innovative discovery science with investment to find solutions to areas of significant medical need.


Gold Members A

Agenus UK Limited Unit 315, Cambridge Science Park, Milton Road, Cambridge CB4 0WG, UK Tel: 01223 791 410 Email: julie.coe@agenusbio.com Website: www.agenusbio.com Contact: Julie Coe

Agenus, Inc. (www.agenusbio.com) is an immuno‑oncology company focused on the discovery and development of revolutionary new treatments that engage the body’s immune system to benefit cancer patients. By combining multiple powerful platforms, Agenus has established a highly integrated approach for the discovery, development and manufacture of monoclonal antibodies that modulate targets of interest. In addition, Agenus’ cancer vaccine programme includes three proprietary platforms focused on individualised and off‑the‑shelf vaccines uniquely designed for each patient. Agenus’ broad portfolio of novel checkpoint and other immuno‑modulatory monoclonal antibodies, vaccines and adjuvants work in combination to provide the opportunity to create best‑in‑class therapeutic regimens.

Allema International Ltd 4 Priory Road, Kenilworth CV8 1LL, UK Tel: 07495 645 247 Email: omerle@allema‑international.com Website: www.allema‑international.com Contact: Olivier Merle

Allema International Ltd was founded in 2015 in response to a need within the life science research tools industry for guidance with marketing, global distribution, business development, and operations services. Thanks to a wide network of distributors and manufacturers built over 20 years of collaborations and global business development in the life science sector, we assist our clients in centralising a broad range of services from operations to international sales.

Apollo Therapeutics LLP Stevenage Bioscience Catalyst, Stevenage, Hertfordshire SG1 2FX, UK Email: info@apollotherapeutics.com Website: www.apollotherapeutics.com Contact: Dr Richard Butt

Apollo Therapeutics is a unique collaboration between three global pharmaceutical companies (GSK, J&J and AZ) and the technology transfer offices of Imperial College London, University College London and the University of Cambridge. This is the first time that three global pharmaceutical companies and the tech transfer offices of three world leading universities have come together to form a joint enterprise, resulting in a truly innovative venture. Apollo will support translational research, shaping projects at an early stage to optimise discovery and the delivery of new breakthrough treatments for onward development.

Aqdot Ltd Iconix Park, London Road, Cambridge CB22 3EG, UK Tel: 01223 928 000 Email: info@aqdot.com Website: www.aqdot.com

Aqdot is a specialist chemical company with a focus and expertise in intelligent encapsulation technology. Aqdot’s proprietary technology and know‑how enables valuable active products to be protected, delivered and programmed to release where and when required. This unique and disruptive platform technology has the potential to be game‑changing in a wide range of industries, including household products, fragrances, personal care, agrochemicals, composites/resin curing and pharmaceuticals. Identifying unmet needs in these sectors, we develop products that enable our customers to introduce novel and differentiated brands, reduce manufacturing costs and make a truly positive impact on the environment.

www.onenucleus.com | 49


Gold Members A

Arecor Limited Chesterford Research Park, Little Chesterford, Essex CB10 1XL, UK Tel: 01223 426 060 Email: info@arecor.com Website: www.arecor.com Contact: Sarah Howell

Arecor is a leader in developing superior biopharmaceuticals through the application of its innovative formulation technology platform. Arecor is leveraging this platform to develop a portfolio of proprietary products, enabling improved treatments for diabetes care via the innovative reformulation of approved proteins and peptides. Arecor’s diabetes product portfolio includes stable aqueous glucagon for emergency and artificial pancreas use, novel insulin formulations to deliver ultra‑rapid acting insulin analogues and ultra‑concentrated rapid acting insulin to enable the miniaturisation of devices.

Artios Pharma Limited Babraham Hall, Babraham Research Campus, Cambridge CB22 3AT, UK Tel: 01223 804 180 Email: info@artiospharma.com Website: www.artiospharma.com Contact: Andrew Muncey

Artios is a leading independent DNA damage response (DDR) company focused on developing first‑in‑class treatments for cancer. Established in May 2016, the company is led by an experienced scientific and leadership team with proven expertise in DDR drug discovery. Artios is building a pipeline of next generation DDR programmes, including through a unique partnership with Cancer Research Technology (CRT), the development and commercialisation arm of Cancer Research UK (CRUK), and with leading DNA repair researchers worldwide. The company’s investors include SV Life Sciences, Merck Ventures, Imperial Innovations, Arix Bioscience plc, CRT Pioneer Fund and AbbVie.

Asterand Bioscience UK 2a Orchard Road, Royston SG8 5HD, UK Tel: 01763 211 600 Fax: 01763 211 555 Email: advantage@asterandbio.com Website: www.asterandbio.com Contact: Annette Palmer

Asterand Bioscience is the leading global provider of high quality, well‑characterised human tissue and human tissue‑based research services to support the discovery and development of drugs and diagnostics. We provide human‑based solutions to pharmaceutical, biotechnology and diagnostics companies, to accelerate the identification and validation of drug targets and biomarkers, and to provide actionable data for the selection of drug candidates with an increased likelihood of clinical success.

Astex Pharmaceuticals – UK 436 Cambridge Science Park, Milton Road, Cambridge CB4 0QA, UK Tel: 01223 226 200 Fax: 01223 226 201 Website: www.astx.com

50 | One Nucleus Directory 2017

Astex is a leader in innovative drug discovery and development, committed to the fight against cancer and diseases of the CNS. Astex is developing a proprietary pipeline of novel therapies and has partnered products being developed under collaborations with leading pharmaceutical companies. As part of Japan’s leading pharmaceutical company, Otsuka Pharmaceutical, Astex operates from two sites with drug discovery research headquarters in Cambridge, UK, and clinical development headquarters in Pleasanton, California. Otsuka Group employs approximately 43,000 people globally with products available in more than 80 countries worldwide. For information about Otsuka Pharmaceutical, visit www.otsuka.co.jp/en. For information about Astex, visit www.astx.com.


Gold Members B

AstriBio Limited Sumpter House, 8 Station Road, Histon, Cambridge CB24 9LQ, UK Email: adam@astribio.com Website: www.astribio.com Contact: Adam Wilkinson

Providing consultancy services to biotech companies including: R&D team management and team building; project management; developing IP; raising funds. Expertise in: drug development; molecular biology and genetics; manufacturing process development; GMP manufacturing.

Auspherix Limited Stevenage Bioscience Catalyst, Gunnels Wood Road, Stevenage SG1 2FX, UK Email: info@auspherix.com Website: www.auspherix.com

Auspherix is an early‑stage anti‑infectives company, offering new hope in the battle against antibiotic resistant bacteria. By developing a new class of antibiotics the company will strengthen the existing arsenal of antibacterial treatments. Auspherix’ preclinical R&D programmes are based on its discovery of antibacterials with a unique profile. These proprietary compounds have demonstrated activity against a broad range of important multidrug resistant (MDR) Gram‑negative and Gram‑positive bacterial strains. The company intends to develop and license these novel antibiotic drug candidate molecules to pharmaceutical companies with expertise in the anti‑infective space.

Babraham Institute Enterprise Limited Babraham Research Campus, Cambridge CB22 3AT, UK Tel: 01223 496 208 Email: info@babrahamie.co.uk Website: www.babraham.ac.uk/industry Contact: Dr Katy Evans‑Roberts

Babraham Institute Enterprise is the trading arm of the Babraham Institute. The Babraham Institute undertakes innovative life sciences research to discover the molecular mechanisms that underlie normal cellular processes, with the aim of improving lifelong well‑being and healthy ageing. It is based on the Babraham Research Campus near Cambridge, which is also home to early‑stage biomedical companies. BIE supports the commercialisation of the Babraham Institute’s science. As part of this role it manages, develops and commercialises the institute’s intellectual property portfolio. BIE also facilitates collaborations between the institute and industry, and arranges access to the institute’s expertise and scientific facilities.

Bactevo Ltd Merrifield Centre, Rosemary Lane, Cambridge CB1 3LQ, UK Tel: 01223 394 200 Email: info@bactevo.com Website: www.bactevo.com Contact: Sarah Fordham

Bactevo, a Cambridge (UK) based company established in 2012, has developed a disruptive technology that fully exploits microbial diversity to discover and develop new medicines for currently intractable diseases. The TarGET (targeted genomic evolution technology) platform is being applied across a very diverse range of microbes using a combination of specialised mutant libraries, next generation sequencing, proprietary data‑sorting algorithms and ultra‑rapid screening to functionally screen for molecules that give a desired phenotype (disease‑treating). The technology is being applied with various challenging therapeutic targets, with collaborations with pharma, biotech and clinical groups.

www.onenucleus.com | 51


Gold Members B

Bicycle Therapeutics Limited Meditrina Building, Babraham Research Campus, Cambridge, Cambridgeshire CB22 3AT, UK Tel: 01223 261 503 Email: info@bicycletherapeutics.com Website: www.bicycletherapeutics.com

Bicycle has developed a proprietary bicyclic peptide technology that enables the discovery of a new class of drug candidates with antibody‑like selectivity and specificity. The company is well financed by a group of top‑tier VCs. The company is applying the technology to projects in areas including oncology. The company has a collaboration on a target in ophthalmology and plans to enter selected additional research collaborations with pharma partners. On October 6, 2014 Bicycle secured a £20 million Series A funding.

BioPark Broadwater Road, Welwyn Garden City, Hertfordshire AL7 3AX, UK Tel: 01707 356 100 Email: info@biopark.co.uk Website: www.biopark.co.uk Contact: Peter Fletcher

BioPark provides ready‑to‑use specialist laboratories, serviced office space and conference facilities for bioscience and health technology businesses, encouraging growth and the development of new products and technologies. It is part of the University of Hertfordshire Group and offers opportunities for collaborative research with the University. Located in Welwyn Garden City, BioPark provides excellent transport links to central London, Cambridge, and Heathrow, Stansted and Luton international airports. The 6000m2 of rentable space is ideally suited for business expansion and includes chemistry and biology labs, a Containment Level 3 (Cat 3) lab and a data centre.

Biotechnology Innovation Organization (BIO) 1201 Maryland Avenue, SW, Suite 900, Washington, DC 20024, USA Tel: +1 202 962 9200 Fax: +1 202 488 6301 Email: biomember@bio.org Website: www.bio.org Contact: Membership Department

BlueGnome Ltd CPC4, Capital Park, Fulbourn, Cambridge CB21 5XE, UK Website: www.cambridgebluegnome.com

52 | One Nucleus Directory 2017

BIO (www.bio.org) represents almost 1000 biotechnology companies, academic institutions, state biotechnology centres and related organisations across the United States and in more than 30 other nations. BIO members are involved in the research and development of innovative healthcare, agricultural, industrial and environmental biotechnology products. BIO also produces the BIO International Convention, the world’s largest gathering of the biotechnology industry, along with industry‑leading investor and partnering meetings held around the world. See www.bio.org/events for more information.


Gold Members C

Cambridge Agile Solutions Limited Suite 29, Middle Court, Copley Hill Business Park, Babraham, Cambridge CB22 3GN, UK Tel: 01223 839 802 Email: mv@cambridgeagile.com Website: www.cambridgeagile.com Contact: Dr Mariana Vaschetto

Cambridge Agile Solutions provides product development, marketing and sales services to technology companies. We are an international network of experienced professionals dedicated to working with research organisations, individuals and small companies to help them understand the importance of marketing, sales and developing products and services that the market actually wants. We help you in starting up a business or launching a spin‑out company. We have a network of graphic designers, website hosting, sales and marketing teams that can make the process of starting up or expanding much simpler and painless.

Cambridge Allergy Ltd ideaSpace Bay 13, Cambridge Biomedical Campus CB2 0SP, UK Email: info@camallergy.com Website: www.camallergy.com Contact: Sherden Timmins

Camallergy is preparing for a phase 3 study of a treatment for peanut allergy based on 84 and 91 per cent success in phase 2 trials. Peanut allergy is the primary market in food allergy, affecting around 6 million in Europe and the USA, and is the most common cause of severe and fatal food‑related allergic reactions.

Cambridge Biolabs Limited St John’s Innovation Centre, Cowley Road, Cambridge CB4 0WS, UK Email: info@cambridge‑biolabs.com Website: www.cambridge‑biolabs.com Contact: Paulina Chilarska

We are a biotech‑meets‑tech company developing personalised skincare solutions consisting of digital skin diagnosis followed by bespoke cosmetic formulation to meet the unique needs of unique people. Our idea stems from the observation that millions of people all around the world use ineffective or unsuitable cosmetics every day because the off‑the‑shelf products currently available on the market do not correspond to the complex set of individual needs. This leads to inadvertent negligence and wrong choices due to lack of optimal solution.

Cambridge Epigenetix Limited Jonas Webb Building, Babraham Campus, Babraham, Cambridgeshire CB22 3AT, UK Tel: 01223 804 260 Fax: 01223 790 219 Email: info@cegx.co.uk Website: www.cambridge‑epigenetix.com Contact: Jason Mellad

Cambridge Epigenetix (CEGX) employs expertise in chemical biology to develop groundbreaking epigenetics tools. Our easy‑to‑use products are of the highest quality and will kickstart your research programme. Our first product, TrueMethyl, utilises innovative oxidative bisulphite sequencing (oxBS‑Seq) technology, developed at the University of Cambridge, to pioneer quantitative, single‑base resolution sequencing of hydroxymethylcytosine (5hmC) and 5‑methylcytosine (5mC).

www.onenucleus.com | 53


Gold Members C

Cambridge Innovation Capital The Hauser Forum, 3 Charles Babbage Road, Cambridge, Cambs CB3 0GT, UK Tel: 01223 764 875 Email: enquiries@cicplc.co.uk Website: www.cicplc.co.uk Contact: Louise Rich

Cambridge Innovation Capital (‘CIC’) invests in intellectual property rich companies in the Cambridge Cluster, combining a unique relationship with the University of Cambridge with deep financial and industry links to the area. The company strives to build leading businesses using a long term return strategy – removing the pressure to deliver the early exits associated with the traditional venture capital model. CIC is led by an experienced investment team, an outstanding board and advisory panel of leading scientists and entrepreneurs, backed by long term institutional and strategic investors.

Cambridge Research Biochemicals 17‑18 Belasis Court, Belasis Hall Technology Park, Billingham, Cleveland TS23 4AZ, UK Tel: 01642 567 180 Fax: 01642 567 181 Email: crbsales@crbdiscovery.com Website: www.crbdiscovery.com Contact: Emily Humphrys

Cambridge Research Biochemicals (CRB) offers over 36 years of expertise in providing custom‑made research tools to the life science community. Established in 1980, CRB is the world’s second oldest peptide company and specialises in everything peptide, from design to synthesis, modification and labelling. CRB also generates target‑specific antibodies to novel proteins and their peptide surrogates. Our chemical expertise is further applied to fluorescent labelling of peptides, antibodies and proteins and we can offer advice on appropriate fluorescent dyes or chelates. CRB works in partnership to offer chemistry services, radiolabelling, europium labelling and PNA.

Cantab Anti‑Infectives Ltd BioPark, Broadwater Road, Welwyn Garden City, Hertfordshire AL7 3AX, UK Tel: 01707 356 132 Fax: 01707 356 131 Email: mail@cantabanti.com Website: www.cantabanti.com Contact: Mike Dawson

Cantab Anti‑Infectives is focused exclusively on the discovery and development of novel antibacterial agents to treat bacterial infections. Current programmes are based around a class of antibiotics called polymyxins which are last resort antibiotics for serious Gram‑negative infections. Cantab Anti‑Infectives continues to explore new product opportunities both within its existing candidate series and from new agents with the potential to offer significant advantage over current therapies.

Cerevance Ltd 418 Cambridge Science Park, Cambridge CB4 0PZ, UK Email: info@cerevance.com Website: www.cerevance.com

54 | One Nucleus Directory 2017

Cerevance is a new pharmaceutical company focused on central nervous system diseases. Our strengths include a powerful technology platform, a pipeline of novel discovery-stage and clinical-stage compounds, and a proven team. We believe that we are well positioned to deliver life-changing therapeutics for patients who have brain-related disorders, while creating value for our employees and shareholders.


Gold Members C

Clean Cells Parc d’Activités Vendée Sud‑Loire 1, F‑85600 Boufféré, France Tel: +33 2 51 09 27 57 Email: contact@clean‑cells.com Website: www.clean‑cells.fr Contact: Laurent Ciavatti

Clean Cells is a 16‑year‑old CRO which specialises in: quality control testing (biosafety, identity, purity and potency), cell and virus banks manufacturing and storage, viral clearance studies and customised bioassays development. Clean Cells is a GLP/GMP‑certified company providing high quality services that comply with global regulatory guidelines (Europe, USA, Japan and ICH). A strong focus is placed on R&D for either internal or external needs and represents 30 per cent of our activity. Our 600m2 facility is based in Boufféré, near Nantes (France).

Convergence Pharmaceuticals Ltd Building 900, Babraham Research Campus, Cambridge, Cambs CB22 3AT, UK Tel: 01628 501 000 Email: info@biogen.com Website: www.convergencepharma.com

Convergence Pharmaceuticals, a Biogen company, is focused on the development of novel, high value analgesics for the treatment of chronic pain. New approaches are desperately needed in this field because current medicines for chronic pain are characterised by poor efficacy and side effects. Our research targets the points of convergence in chronic pain signalling through the blockade of specific ion‑channels. Convergence’s world‑class expertise in ion channel electrophysiology and medicinal chemistry has produced a pipeline of voltage gated sodium channel (NaV) blockers that is unmatched in industry.

Credos Consulting Limited Brushwood, 2 Dukes Road, Lindfield, West Sussex RH16 2JH, UK Tel: 01444 226 320 Email: charles.owen@credos‑bio.co.uk Website: www.credos‑bio.co.uk Contact: Dr Charles Owen

Credos is a specialist consultancy for the discovery and development of therapeutic antibodies and other biologics. Our expertise spans all disciplines including early discovery, early development, early stage manufacturing and technical development, translational research, clinical development and regulatory approval. Each of our consultants is a leading expert in their discipline with a track‑record of success in the biotherapeutics field. We offer tailored consultations to address bespoke project needs, as well as virtual teams of experts to support and lead more complex or challenging projects. We work with a range of academic and commercial clients, both large and small.

Cresset New Cambridge House, Bassingbourn Road, Litlington, Cambridgeshire SG8 0SS, UK Tel: 01223 858 890 Email: enquiries@cresset‑group.com Website: www.cresset‑group.com

Save time and money using our in silico methods to identify the molecules that matter to your project. Discover, design and optimise the best small molecules with: unrivalled insight into your protein‑ligand systems; outstanding visualisation and multi‑parameter optimisation tools; and biologically relevant searches of millions of compounds. Chemists from the world’s leading research organisations trust us to help them understand the key chemical interactions that underpin biological activity. We provide software and services to eight out of the top 10 pharmaceutical companies. Use our software in‑house or engage our scientists to work alongside your research team.

www.onenucleus.com | 55


Gold Members C

Cyclofluidic Ltd BioPark, Broadwater Road, Welwyn Garden City, Hertfordshire AL7 3AX, UK Tel: 01707 358 766 Email: info@cyclofluidic.co.uk Website: www.cyclofluidic.co.uk Contact: Dave Parry

Cyclofluidic utilises CyclOps™, its proprietary integrated drug discovery platform, to accelerate early stage discovery projects for its partners. CyclOps™ connects chemistry, purification and biochemical assay with powerful machine learning methods to enable lead molecules to be assayed minutes, rather than weeks, after they are designed. Removing the latency between synthesis and biological data, our unique approach puts synthesis, screening and molecular design back together in a single laboratory allowing fast iterative exploration of large areas of diverse chemical space. Cyclofluidic has completed more than 20 projects with partners, delivering lead molecules with the CyclOps platform and experienced industry team.

Cyclogenix Stevenage Bioscience Catalyst, Gunnels Wood Road, Stevenage SG1 2FX, UK Website: www.cyclogenix.com

Cypralis Limited Babraham Hall, Babraham Research Campus, Cambridge, Cambridgeshire CB22 3AT, UK Tel: 01277 367 020 Fax: 01277 367 099 Email: contact@cypralis.com Website: www.cypralis.com

Cypralis is focused on the discovery and development of highly innovative therapeutics for the modulation of peptidyl‑prolyl isomerases (PPIases), a large family of druggable protein targets known to be involved in many acute and chronic diseases. Cypralis aims to develop its cyclophilin inhibitors for acute diseases associated with tissue injury to clinical proof of concept, whereas for chronic conditions such as inflammatory and degenerative diseases, it seeks to establish R&D partnerships with pharma companies. Cypralis has existing partnerships with Gilead Sciences (liver diseases) and Janssen Pharmaceuticals (neurodegenerative diseases). Further information is available at www.cypralis.com.

Cytocell Limited 3‑4 Technopark, Newmarket Road, Cambridge CB5 8PB, UK Tel: 01223 294 048 Fax: 01223 294 986 Email: probes@cytocell.com Website: www.cytocell.com

56 | One Nucleus Directory 2017

Cytocell Ltd is a leading European developer and manufacturer of FISH probes for use in both routine cytogenetics and in the analysis and classification of cancers. Recently, the company has focused on developing products for oncology and now has a catalogue of some 350 products for cytogenetics, haematology and solid tumour analysis as well as developing custom FISH probes for customers with specific interests under the myProbes® brand. Cytocell’s products are available through a well established distributor network, covering more than 60 countries worldwide. Cytocell’s FISH probe service is currently proving to be invaluable to cancer researchers and clinicians worldwide.


Gold Members D

DefiniGEN B280 Moneta, Babraham Research Campus, Cambridge CB22 3AT, UK Tel: 01223 497 106 Email: marcus@definigen.com Website: www.definigen.com Contact: Dr Marcus Yeo

DefiniGEN aims to enable better disease research and reduce the cost of drug discovery by providing highly functional human cells and metabolic disease models to the drug discovery sector. These cells are used in drug discovery lead optimisation and toxicity programmes. The company’s proprietary production platform OptiDIFF robustly generates human cell types using hiPSC (human Induced Pluripotent Stem Cell) technology. DefiniGEN has utilised this platform to produce validated libraries of disease modelled human liver and pancreatic cells. DefiniGEN provides these human disease modelled cells for a range of inherited metabolic liver diseases and diabetes.

Digital Salutem 71‑75 Shelton Street, Covent Garden, London WC2 9JQ, UK Email: joao@digitalsalutem.com Website: www.digitalsalutem.com Contact: Joao Bocas

We are digital health experts who represent and support your company to acquire new clients in a new market. #digitalhealth #wearables #IoT #bigdata #startups.

Discuva Ltd Merrifield Centre, Rosemary Lane, Cambridge, Cambs CB1 3LQ, UK Tel: 01223 394 200 Fax: 01223 394 201 Email: info@discuva.com Website: www.discuva.com Contact: David Williams

Discuva is a Cambridge, UK‑based drug discovery company producing new antibiotics to meet the critical unmet medical need in the clinic. The company has proprietary technologies that allow the rapid identification and development of targeted next generation antibiotics against emerging and drug‑resistant pathogens. Discuva currently has several specific antimicrobial programmes mainly focused on Gram‑negative bacteria that cause major hospital and community‑based infections. The small molecule drugs produced by Discuva are being developed to have two major advantages over conventional antibiotics: no development of cross resistance and fewer side effects giving safer, more effective treatments with a longer market life.

Domainex Ltd Chesterford Research Park, Little Chesterford, Saffron Walden, Essex CB10 1XL, UK Tel: 01223 743 170 Email: enquiries@domainex.co.uk Website: www.domainex.co.uk Contact: Tom Mander

Domainex is an integrated drug discovery services company with a reputation for speed and innovation, built on an exceptional track record of drug candidate delivery. Domainex reduces industry average drug discovery timelines by as much as 30 per cent through the application of proprietary technologies and a focused approach. Services offered span hit discovery, hit‑to‑lead and lead optimisation phases of drug discovery. They include: protein production; assay development; hit identification using virtual, fragment or screening approaches; medicinal chemistry supported by X‑ray crystallography; CADD; physical chemistry; and in vitro ADME/PK testing. We support translational research grant applications.

www.onenucleus.com | 57


Gold Members D

Dr. Reddy’s Custom Pharmaceutical Services (CPS) 410 Cambridge Science Park, Milton Road, Cambridge CB4 0PE, UK Tel: 01223 728 036 Email: contactcps@drreddys.com Website: www.drreddys‑cps.com Contact: Gaurab Sengupta

CPS (Custom Pharma Services) draws on Dr. Reddy’s domain expertise in pharmaceutical development and manufacturing to provide innovators with customised services and solutions for starting materials, intermediates, active ingredients, and finished dosage forms. CPS partners have access to the best talents and technologies (e.g. peptides, chirals, HPAPIs, steroids, actived mPEGs) as well as an extensive global delivery network and a vast intermediate and API portfolio. Committed to ensuring our partners’ success, our partnership model enables pharmaceutical companies to reach more markets faster and efficiently by leveraging a cost leadership and presence across the globe – because good health can’t wait.

DRG Consultancy Ltd 104 High Street, Bridge, Canterbury CT4 5AR, UK Tel: 07946 637 847 Email: daverg8@hotmail.com Contact: Dave Russell‑Graham

DRG Consultancy Ltd was set up at the start of 2016 by Dave Russell‑Graham primarily as a proactive, hands on, project management service to the life sciences industry. With over 30 years of experience in pharmaceutical development, much of it focused on late stage technology transfer and facility development, Dave has worked with a diverse range of clients in the public and private sectors, including Coalesce Product Development and INVEST Essex. A prolific networker, Dave is also focused on business development and if he can’t help, he’s almost sure to be able to find someone else who can.

Eagle Genomics Ltd Wellcome Genome Campus, Biodata Innovation Centre, Hinxton, Cambridge CB10 1DR, UK Tel: 01223 654 481 Email: info@eaglegenomics.com Website: www.eaglegenomics.com Contact: Abel Ureta‑Vidal

Unleashing the power of omics information for data driven discovery. Eagle believes that innovation in discovery R&D is achieved through better access, analysis and utilisation of biological datasets. Eagle accelerates the opportunities offered by genomics and new data generation technologies to address some of the key challenges in drug and product development for improved well‑being and personalised medicine. Eagle provides intelligent and scalable data integration and analysis services, with cloud‑based technologies and bioinformatics professional services to help global pharma and biotech companies realise the full potential of their data and metadata. Faster discoveries through improved integration.

Earlham Institute Norwich Research Park, Colney, Norwich, Norfolk NR4 7UZ, UK Tel: 01603 450 001 Email: marcomms@earlham.ac.uk Website: www.earlham.ac.uk Contact: Hayley London

58 | One Nucleus Directory 2017

A world‑class research institute for the study of genomics and bioinformatics, EI’s National Capability in Genomics offers a state‑of‑the‑art DNA sequencing and computing facility, hosting one of the largest data centres dedicated to life science research in Europe. Our diverse projects covering the breadth of life on earth are helping us to improve human, animal and plant health – while tackling global issues of food security, climate change, environment conservation and human well‑being.


Gold Members E

enplas (Europe) Limited Suite 4 Science Village, Chesterford Research Park, Little Chesterford, Cambridge CB10 1XL, UK Website: www.enplas.co.jp/english

Envigo Woolley Road, Alconbury, Huntingdon, Cambridgeshire PE28 4HS, UK Tel: 01480 892 000 Website: www.envigo.com Contact: Clare Hargreaves

Envigo provides essential research services, models and products for biopharmaceutical, crop protection, and chemical companies as well as universities, governments and other research organisations. Our business is founded on a dedication to customer service and the expertise and experience of our 3800 people. With over 50 locations worldwide we are committed to helping customers realise the full potential of their research and products as we work together to build a healthier and safer world. Read more at www.envigo.com.

Essen BioScience Ltd BioPark, Broadwater Road, Welwyn Garden City, Hertfordshire AL7 3AX, UK Tel: 01707 358 688 Fax: 01707 358 687 Website: www.essenbioscience.com Contact: Dr DJ Trezise

Essen BioScience provides instrumentation, reagents, and analysis software that enable researchers to monitor and quantify a wide variety of cellular processes over time. Our flagship product, IncuCyte®, enables automated live‑cell imaging and real‑time data analysis, over hours to weeks inside your incubator. Whether monitoring common cellular processes such as proliferation and apoptosis or more advanced phenotypes, including migration/invasion, T‑cell killing or neurite outgrowth, IncuCyte® yields kinetic data and insight far beyond that achievable with conventional end‑point, non‑image based approaches. Combine IncuCyte® with our range of IncuCyte™ live‑cell imaging reagents for integrated solutions of kinetic cell based assays.

Evonetix 29 Cambridge Science Park, Cambridge CB4 0DW, UK Tel: 01223 392 650 Fax: 01223 423 373 Email: joe.brennan@evonetix.com Website: www.evonetix.com Contact: Nick McCooke

Evonetix is a new start‑up based in Cambridge seeking to develop and commercialise a novel approach to DNA synthesis.

www.onenucleus.com | 59


Gold Members F

F‑star Biotechnology Ltd Eddeva B920, Babraham Research Campus, Cambridge CB22 3AT, UK Tel: 01223 497 400 Fax: 01223 497 461 Email: cambridge@f‑star.com Website: www.f‑star.com Contact: Jane Dancer (CBO)

F‑star is a clinical‑stage biopharmaceutical company developing bispecific antibody immuno‑oncology products selected for their potential to transform the treatment of cancer. Through the application of its highly efficient Modular Antibody Technology™ platform, F‑star is the only biotechnology company able to create bispecific antibodies where the second binding site is in the constant Fc region of an antibody. The strength of the technology and programmes has been leveraged through partnerships with leading biopharmaceutical companies including AbbVie, Bristol‑Myers Squibb, Merck Serono, Boehringer Ingelheim and Denali Therapeutics.

Fairjourney Biologics Rua do campo Alegre, 823, P‑4150‑180 Porto, Portugal Website: www.fjb.pt

Fairjourney Biologics, an established company with an outstanding track record of biotech, biopharmaceutical and big pharma partners, offers a range of assets and services on antibody engineering, discovery and production. Being one of the few profitable biotech companies, Fairjourney Biologics has implemented a co‑development and R&D arm to complement its fee‑for‑service main unit. The company has validated a naïve human library and a llama naïve library. The unrivalled experience in llama, mice and rat antibody discovery contributes to position the company at the forefront of antibody discovery and engineering.

Fluofarma 2, rue Robert Escarpit, F‑33600 Pessac, France Tel: +33 5 40 00 30 60 Email: contact@fluofarma.com Website: www.fluofarma.com Contact: Melanie Jamard

Fluofarma is a cell biology company. Combining live content and high‑content imaging, Fluofarma has developed a cost‑efficient strategy to accurately determine the efficacy and toxicity profile of lead compounds, and to explore their underlying mechanism of action. Fluofarma also develops and performs custom biomarker assays based on high‑content analysis technologies to support specific needs at preclinical and clinical stages. Biomarker assays are optimised for automated, multiplex and high‑throughput biomarker quantification at the single‑cell level across large collections of blood and tissue samples.

GalenAuxi Ltd Church Crookham GU52, UK Tel: 07931 933 594 Email: eguillabert@galenauxi.co.uk Website: www.galenauxi.co.uk Contact: Edouard Guillabert

60 | One Nucleus Directory 2017

GalenAuxi Ltd is an independent consultancy, providing support to the pharmaceutical industry based on a broad expertise including pre‑formulation, solid state characterisation, formulation development and clinical trial product manufacture. GalenAuxi Ltd provides tailor-made services based on your need and our experience. Further than just providing advice and thanks to a broad network of experts and a strong technical experience, we are able to provide the practical work or help you outsource it to meet your need. Short term/part time contracting can also be considered (to be discussed on a case by case basis and depending on availability).


Gold Members H

GENEWIZ UK Ltd Hope End, Takeley CM22 6TA, UK Website: www.genewiz.com

A full‑service provider, GENEWIZ provides Sanger DNA sequencing, gene synthesis, molecular biology, high throughput/next generation sequencing, bioinformatics and GLP regulatory services. Our customers at top‑tier pharmaceutical, biotechnology and academic institutions, as well as cutting‑edge start‑ups, rely on GENEWIZ’s proprietary technologies for consistent, reliable, high‑quality data, even on the most difficult projects.

Greater Cambridge Greater Peterborough Enterprise Partnership (LEP) Unit 3, The Incubator, Alconbury Weald Enterprise Campus, Alconbury Airfield, Huntingdon PE28 4WX, UK Tel: 01480 277 180 Email: info@gcgp.co.uk Website: www.gcgp.co.uk Contact: Laura Welham‑Halstead

The Greater Cambridge Greater Peterborough Enterprise Partnership (LEP) works hard to create the right conditions for economic growth across its area. It is focused on overcoming the key barriers to economic growth, which include infrastructure, skills and business support. With some of the most innovative companies in the world located within the GCGP area, the LEP is working hard to enable the delivery of the homes, transport network and skilled workforce required to support this unique environment. Via Signpost 2 Grow, the LEP can help to connect businesses with the help, advice and funding they need to grow.

Healark Ltd 15 Kirkby Close, Cambridge CB4 1XP, UK Tel: 07570 896 451 Email: leire@healark.com Website: www.healark.com Contact: Leire Escudero Ibarz

Healark aims to enhance patients’ cancer journeys and potentially boost treatment outcomes by encouraging patients to combat the effects of cancer with science‑backed lifestyle recommendations. Our digital healthcare companion is scientifically designed to modulate lifestyle factors. Accumulating scientific evidence shows that behavioural change in areas such as exercise, diet and nutrition, sleep, mental health and energy conservation can have a positive impact on a patient’s quality of life and, in some cases, the outcome of their treatment. Healark also benefits friends, family and healthcare professionals by updating them on patient progress. Healthcare professionals can remotely monitor progress.

Hennings Consulting Ltd 2 Albury Heights, 8 Albury Road, Guildford GU1 2BT, UK

www.onenucleus.com | 61


Gold Members H

Horizon Discovery Group plc 8100 Cambridge Research Park, Waterbeach, Cambridge, Cambridgeshire CB25 9TL, UK Tel: 01223 655 580 Fax: 01223 655 581 Email: info@horizondiscovery.com Website: www.horizondiscovery.com Contact: Chris Claxton

Horizon Discovery (LSE: HZD) is a world‑leading gene editing company that designs and engineers genetically‑modified cells, applying them in research and clinical applications to advance human health. Horizon’s proprietary gene editing platform, able to alter almost any gene sequence, has generated a catalogue of over 23,000 cell and in vivo models that recapitulate the genetic anomalies found in diseases like cancer. These models have been adopted by c1600 unique organisations to better understand the genetic drivers of disease, and by Horizon in a range of services offered to customers as well as in the company’s own R&D pipeline.

Illumina Cambridge Ltd Chesterford Research Park, Little Chesterford, Nr Saffron Walden, Essex CB10 1XL, UK Tel: 01799 532 300 Fax: 01799 532 301 Website: www.illumina.com

Illumina is a leading developer, manufacturer, and marketer of life science tools and integrated systems for the analysis of genetic variation and function. We provide innovative sequencing and array‑based solutions for genotyping, copy number variation analysis, methylation studies, gene expression profiling, and low‑multiplex analysis of DNA, RNA, and protein. We also provide tools and services that are fuelling advances in consumer genomics and diagnostics. Our technology and products accelerate genetic analysis research and its application, paving the way for molecular medicine and ultimately transforming healthcare.

Imperial White City Incubator Level 1 Bessemer Building, Imperial College, London SW7 2AZ, UK Tel: 020 8811 6730 Email: james.sheppard@imperialinnovations.co.uk Website: www.imperialinnovations.co.uk/ technology‑transfer/incubator Contact: James Sheppard

The Imperial White City Incubator is a hub for innovation and entrepreneurship, providing office and laboratory space for start-up deep science companies. Early stage companies can benefit from a well-developed incubation programme and being in close proximity to eminent scientists and experts at Imperial College London. Contact James Sheppard for more information.

In Tandem Limited PO Box 1260, Cambridge CB1 0YH, UK Email: info@intandemlimited.co.uk Website: www.intandemlimited.co.uk Contact: Sue Humphrey

62 | One Nucleus Directory 2017

In Tandem Limited offers a facilitated approach to strategy development and implementation, investigation of business opportunities and business process review. This approach provides a framework for an effective and efficient conversation, leaving people from the business free to think and make decisions. It helps businesses to set a clear way forward to achieve sustainable success over the longer‑term and thereby focus time and money on priority areas. In Tandem Limited works with organisations to ensure that action is taken; to make sure that strategy is brought to life.


Gold Members I

Inivata Limited Li Ka Shing Centre, Robinson Way, Cambridge CB2 0RE, UK Tel: 01223 803 818 Email: liz.macfadyen@inivata.com Website: www.inivata.com

Inivata, a global clinical cancer genomics company, employs the precision of circulating tumour DNA (ctDNA) analysis to improve personalised healthcare. Inivata’s expertise, cutting-edge technology and advanced bioinformatics analysis can detect and characterise cancer-related mutations and enable non-invasive testing at multiple points along the cancer care cycle. Using a simple blood test, Inivata’s proprietary technology provides oncologists with clinically actionable information to guide therapy selection, monitor treatment and detect resistance mutations. Inivata has laboratories and offices in both the USA (Research Triangle Park, NC) and the UK (Cambridge). You can learn more about Inivata on www.inivata.com.

innoFund Innovation Funding Advisors AB Rosornas Väg 17, SE‑18238 Danderyd, Stockholm, Sweden Tel: +46 707 557 006 Email: info@inno‑fund.com Website: www.inno‑fund.com Contact: Heather Marshall‑Heyman

innoFund is a Swedish project management and funding advisory company. We are specialists in life sciences, supporting pharma, biotech and medtech companies to finance and manage development and commercialisation of their innovations. innoFund has a wide network of partners, companies, academia and public bodies in Scandinavia.

Intract Pharma 29‑39 Brunswick Square, London WC1N 1AX, UK Tel: 020 7753 5908 Email: info@intractpharma.com Website: www.intractpharma.com Contact: Bill Lindsay

Intract Pharma specialises in understanding and optimising oral delivery of pharmaceutical products. We offer modelling of drug/formulation behaviour during passage through the GI tract and proprietary delivery methods to ensure reproducible targeted delivery. Our clinically validated technologies are simple to manufacture and amenable to use with small molecules, biologics or live cells.

IONTAS Ltd Unit 2, Iconix Park, London Road, Pampisford, Cambridge, Cambs CB22 3EG, UK Tel: 01223 750 801 Email: admin@iontas.co.uk Website: www.iontas.co.uk Contact: Neil Butt

IONTAS offers phage display technology services for antibody discovery and the supply of phage display libraries. In addition, IONTAS is developing proprietary antibody discovery platforms to improve develop‑ability (mammalian display) and for targeting antibodies against difficult targets.

www.onenucleus.com | 63


Gold Members I

Isogenica Ltd The Mansion House, Chesterford Research Park, Little Chesterford, Saffron Walden CB10 1XL, UK Tel: 01799 533 680 Email: sales@isogenica.com Website: www.isogenica.com Contact: Adam Collier

Isogenica operates a range of discovery platforms supported by state‑of‑the‑art methodologies for identifying antibody and peptide ligands. Our platforms benefit from a combination of intelligent library design and precision Colibra™ library construction, to create synthetic libraries with unprecedented functional diversity. An excellent starting point for traditional and next generation antibody therapeutics.

Isomerase Therapeutics Ltd Suite 9, Science Village, Chesterford Research Park, Little Chesterford CB10 1XL, UK Tel: 01223 911 856 Website: www.isomerase.co.uk Contact: Matthew Gregory

Isomerase Therapeutics is a drug discovery and development company based in Cambridge, UK, with particular expertise in optimised microbial and fungal natural products using cutting-edge biosynthetic engineering, synthetic biology and semi‑synthetic chemistry to drive its research and development efforts. Isomerase offers its expertise and bespoke services to partners through collaborations and also has proprietary technology and early stage drug development programmes available for licensing.

Johnson Matthey PLC (Cambridge) 28 Cambridge Science Park, Milton Road, Cambridge, Cambridgeshire CB4 0FP, UK Tel: 01223 226 160 Fax: 01223 438 037 Email: gwillk@matthey.com Contact: Kevin Gwilliam

Johnson Matthey Fine Chemicals provides high quality, value-adding products and services, meeting the highest standards for companies developing pharmaceuticals, agrochemicals, and other fine and speciality chemicals. Our specialist technologies provide a substantial toolkit for diverse complex chemistries. They include an unmatched portfolio of homogeneous and heterogeneous catalyst technologies; chiral synthesis including chemocatalysis and biocatalysis platforms; controlled substances; highly potent APIs; expertise in drug-conjugate and linker technologies; solid form sciences; manufacturing-scale chromatography and purification sciences; as well as process analytical technologies. Through our comprehensive and fully aligned capabilities, customers globally can benefit from innovative chemistries and efficient services, built on a firm knowledge base that they can trust.

Jupiter Diagnostics Holding Company Ltd London BioScience Innovation Centre, 2 Royal College St, London NW1 0NH, UK Website: www.jupiterdiagnostics.com

64 | One Nucleus Directory 2017


Gold Members L

Keregen Therapeutics Ltd Flat 3, 41‑53 Goswell Road, London EC1V 7EH, UK Website: www.keregen.co.uk

Kymab Limited The Bennet Building, Babraham Research Campus, Cambridge CB22 3AT, UK Tel: 01223 833 301 Fax: 01223 839 133 Website: www.kymab.com

Kymab is a biopharmaceutical company using a proprietary transgenic antibody platform, Kymouse, to discover and develop fully human monoclonal antibody drugs. The technology used to design the Kymouse strains originated from the Wellcome Trust Sanger Institute in Cambridge, UK. Kymouse™ has been designed to maximise the diversity of human antibodies produced in response to immunisation. Selecting from a broad diversity of fully human antibodies assures the highest probability of finding that rare drug candidate with best‑in‑class characteristics.

LabKey (UK) Ltd 52 Jersey Drive, Wokingham, Berkshire RG41 5FR, UK Tel: 01138 680 267 Email: jasonl@labkey.com Website: www.labkey.com Contact: Dr Jason Leadley

LabKey works hand-in-hand with biomedical research organisations to understand the complex data management and workflow challenges faced in today’s research environment, and develop flexible, scalable, extensible solutions to overcome them. Utilising the powerful LabKey Server platform, LabKey solutions help teams gather better data, integrate diverse data types, conduct meaningful analysis, and share research insights with stakeholders and collaborators, all in a secure, web-based environment. LabKey also provides custom software development and professional services to ensure the successful implementation and adoption in each unique research environment.

Lonza Biologics Plc The Portway, Granta Park, Cambridge CB21 6GS, UK Tel: 01223 895 102 Email: yvette.stallwood@lonza.com Website: www.lonza.com Contact: Yvette Stallwood

Lonza is a leading supplier to the pharmaceutics, healthcare and life science industry, headquartered in Basel, Switzerland, with sites worldwide. Based in Cambridge, Lonza’s Applied Protein Services (APS) team improve the quality, safety, efficacy and manufacturability of antibodies, therapeutic proteins, peptides and vaccines. By supporting the selection, optimisation and early process development of drug candidates, APS can help improve your chances of success and mitigate risk. We offer in silico and in vitro services for immunogenicity prediction and assessment, developability assessment (PTM and aggregation prediction), protein engineering and protein production using regulatory approved cell lines.

www.onenucleus.com | 65


Gold Members M

Masthead Bioscience 62 Radegund Road, Cambridge CB1 3RS, UK Tel: 07926 101 832 Email: info@masthead-bioscience.com Website: www.masthead-bioscience.com Contact: Dr Ron Jortner

Masthead Bioscience is a consulting firm specialised in providing solutions and closing knowledge gaps in the life sciences, biotechnology and healthcare space. Through our network of experts, we offer our clients across the industry creative technical solutions, up-to-date information and analysis on technology, medical practices, and healthcare policy – all tailored to address a variety of customer needs. With a solid base in neuroscience, imaging, data-science, bioengineering, medical devices and pharmacology, we are rapidly expanding into the fields of immunology, oncology, antivirals and antibiotics.

Meomics Limited Building 3, Watchmoor Park, Camberley GU15 3YL, UK Tel: 07799 737 073 Email: info@meomics.com Website: www.meomics.com Contact: Julie Wallis

Meomics is an executive coaching and business advisory practice based in London, working with senior executives in the biopharmaceutical industry to accelerate business growth and value creation. The Meomics approach is outcome‑orientated and bespoke, combining performance coaching with healthcare and industry insight and expertise, supporting senior leaders to develop and achieve the right goals for themselves, their teams and their businesses.

Mitochondrial Substrate Invention (MSI) Ltd 39 Glasslyn Rd, London N8 8RJ, UK Tel: 07967 561 263 Email: larisa@mitocholine.com Website: www.mitocholine.com Contact: Larisa Andreeva

Mitochondrial Substrate Invention (MSI Ltd) is formed for developing patented compound for activation and sensitisation of brain insulin receptor (IR‑A), aiming at prevention of cognitive degradation, neuronal protection in diseases characterised by the increased insulin resistance in the brain. The underlying discovery is original mechanism of the mitochondrial control for the activation of brain insulin receptor (IR‑A). Targeting the mitochondrial regulation can cause protection of neuronal cells from ischemic insults, causes memory enhancement and reduction of depressive and anxiety symptoms.

Molecular Warehouse Ltd 8 Huxley Road, Surrey Research Park, Guildford GU2 7RE, UK Email: info@molecularwarehouse.com Website: www.molecularwarehouse.com Contact: Dr Siro Perez

66 | One Nucleus Directory 2017

Our vision is to prevent and control disease by allowing people to have molecular diagnostics tests on their smartphones. We have used synthetic biology to re‑engineer the most successful point of care diagnostic system, glucometers, to detect any disease marker or drug. Our first applications are in chronic kidney disease (therapeutic drug monitoring of immunosuppressants, and hypercalcemia in dialysis), but our platform can be used to any indication. We are interested in discussing with other companies to co‑develop applications in therapeutic drug monitoring, clinical trials, and patient stratification.


Gold Members N

Morphogen‑IX Babraham Research Campus, Babraham CB22 3AT, UK Website: www.morphogen‑ix.com

Mote Research Limited Babraham Hall, Babraham Research Campus, Cambridge CB22 3AT, UK Tel: 01223 804 060 Email: phd@mote.co.uk Website: www.mote.co.uk Contact: Dr Paul H Dear

Six decades on from the double helix, genomics remains a read‑only technology. Our ability to intervene at the genome level in adult humans is essentially zero. Sequence data is used to guide research, to diagnose and to inform – but therapeutic and prophylactic intervention is still limited to the downstream, diverse and biologically messy consequences of genomic variations. Mote is developing somatic editing technology to intervene directly, safely and precisely in the genomes of adult humans to tackle cancer, retroviral diseases and genetic disorders where they start – in the DNA.

New Path Molecular Research Limited Building 580, Babraham Research Campus, Cambridge CB22 3AT, UK

NGS Pipeline 900 Wilshire Dr. STE 202‑45, Troy, Michigan 48084, USA Website: www.ngspipeline.com

www.onenucleus.com | 67


Gold Members N

Novintum Bioscience Limited The London BioScience Innovation Centre, 2 Royal College Street, London NW1 0NH, UK

Nuclera Nucleics Ltd Stevenage Bioscience Catalyst, Gunnels Wood Road, Stevenage SG1 2FX, UK Email: jhuang@nuclera.com Website: www.nuclera.com Contact: Jiahao Huang

At Nuclera, we are building a next-generation DNA synthesis platform for the life science and synthetic biology industry. Equipped with synthetic DNA, researchers can rapidly develop therapeutic agents to life threatening diseases, as well as developing disease-resistant crops and better synthetic materials. Our proprietary, enzyme-based DNA synthesis method will produce high quality, long-length DNA, but using only a fraction of the time compared to currently available vendors.

Onyx Health Maling Exchange, Hoults Yard, Newcastle-upon-Tyne NE6 1AB, UK Tel: 0191 640 3638 Email: enquiries@onyxhealth.com Website: www.onyxhealth.com Contact: Trevor Pill

Onyx Health is a healthcare marketing communications and PR agency with bags of experience, industry know-how, and ability to deliver innovative and impactful campaigns that get results. We have got what it takes to make a product successful, because we know the healthcare market. We specialise in helping our clients reach customers, enter new markets, build brands and increase sales. We pride ourselves on our integrated approach, giving our clients senior level day-to-day support, and constant access to our strategic insight and expertise. Our markets include: pharmaceuticals, medical devices, medical diagnostics and consumer health products.

Origin Sciences Limited Riverside 1, Unit 1, Granta Park, Great Abington, Cambridge, Cambridgeshire CB21 6AD, UK Tel: 01223 750 490 Fax: 01223 892 863 Email: jenny.searle@originsciences.com Website: www.originsciences.com Contact: Jenny Searle

68 | One Nucleus Directory 2017

Origin Sciences develops and manufactures innovative diagnostic tools and assays that enable the detection, diagnosis and monitoring of gastrointestinal (GI) diseases. The OriCol™ sample collection device, Origin’s flagship product in the in vitro diagnostic market, enables convenient and effective clinical sampling of mucocellular material that has migrated through the whole colon to the rectum. Using the OriCol™ technology, Origin Sciences is developing a portfolio of assays, and is seeking collaborations to develop high‑value tests for the GI market.


Gold Members P

Oxford Biotrans Limited 127‑18 Olympic Avenue, Milton Park, Abingdon OX14 4SA, UK Email: info@oxfordbiotrans.com Website: www.oxfordbiotrans.com

We produce high‑value chemicals using patented enzyme technology. Our first product is natural‑grade nootkatone, the flavour and scent of grapefruit.

PepTcell Limited London BioScience Innovation Centre, 2 Royal College Street, London NW1 0NH, UK Tel: 020 7691 1122 Email: ana.fernandez@seekacure.com Website: www.seekacure.com

SEEK’s strategy is to bring safe, effective and low cost medicines to patients as quickly as possible. It does this by using the most advanced understandings in biology and chemistry in the generation of the products through modifications to existing medicines, to improve their efficacy by using existing medicines in new indications, or by creating new chemical entities (‘pioneering science’) and finding the fastest regulatory pathways to bring these products to patients (‘commercially delivered’).

PhoreMost Ltd Building 580, Rm 2011, Babraham Research Campus, Babraham, Cambridge CB22 3AT, UK Tel: 01223 804 163 Email: info@phoremost.com Website: www.phoremost.com Contact: Dr Charli Batley

PhoreMost™ is focused on bringing more effective and affordable targeted medicines to patients. To achieve this aim, PhoreMost is developing a next generation phenotypic screening technology that can discern the best new targets for future therapy and, crucially, how to drug them. This has the potential to significantly increase the diversity of novel therapeutics for cancer and other unmet diseases. Based on the company’s proprietary Protein Interference (PROTEINi®) technology, PhoreMost has developed SITESEEKER®; a platform that can systematically unmask cryptic druggable sites in the human genome and then link them to useful therapeutic functions in a live‑cell context.

Precision NanoSystems UK Limited 50-655 West Kent Ave. North, Vancouver, British Columbia V6P 6T7, Canada Email: info@precision‑nano.com

Precision NanoSystems’ proprietary NanoAssemblr™ Platform enables the rapid and controlled manufacture of nanomedicines. It enables controlled, bottom‑up, molecular self‑assembly of nanoparticles via custom‑engineered microfluidic mixing cartridges that allow millisecond mixing of nanoparticle components at the nanolitre scale. Rapid mixing on a small scale allows reproducible control over particle formation. The NanoAssemblr Platform solves significant issues associated with the incumbent nanoparticle manufacturing such as tuning for size.

www.onenucleus.com | 69


Gold Members P

ProMetic Biosciences Ltd Horizon Park, Barton Road, Comberton, Cambridge CB23 7AJ, UK Tel: 01223 420 300 Fax: 01223 420 270 Email: sales‑pbl@prometic.com Website: www.prometic.com Contact: Andy Davies

ProMetic BioSciences Ltd (PBL) is the UK‑based subsidiary of ProMetic Life Sciences, a global biopharma company headquartered in Canada. Since 1987, PBL has pioneered the design, development and manufacture of chromatography adsorbents for lab‑scale and industrial‑scale bioprocessing, enabling its clients to produce safe and economical therapeutic products. With over 29 years of experience and success in the development of innovative biochromatography products and services, PBL is a world leader in its field. PBL specialises in protein purification; contaminant removal; pathogen reduction; custom adsorbent development and manufacture; and downstream process development.

Prosynth Ltd Unit 2, Bull Lane Industrial Estate, Acton, Sudbury, Suffolk CO10 0BD, UK Tel: 01787 883 320 Fax: 01787 883 301 Email: info@prosynth.com Website: www.prosynth.com Contact: Rebecca Payne

ProSynth is perfectly placed to work with companies and academic research institutes to meet custom synthesis requirements. During our 24 years of operation we have achieved in excess of 150 worldwide clients and become a trusted supplier to many global pharmaceutical companies. With versatile manufacturing capabilities and competence in multi‑step chemical synthesis, ProSynth serves four main business areas: custom synthesis, organic electronics, medicinal chemistry support and advanced intermediates. ProSynth delivers a competitive, comprehensive and confidential service which routinely includes weekly updates and a detailed campaign report on completion. We would be delighted to discuss your requirements.

Protavio Ltd Stevenage Bioscience Catalyst, Gunnels Wood Road, Stevenage SG1 2FX, UK Website: www.protavio.com

Protavio is a drug discovery solutions provider using advanced systems pharmacology analyses with multi‑omics data. Our state‑of‑the‑art screening facilities and bioinformatics tools enable us to provide solid computational analysis and experimental validation. Our drug discovery portfolio includes target identification, target validation, biomarker discovery and development, and drug repositioning. We have worked with most major pharmaceutical companies and top academic institutes in the areas of chronic kidney disease, fibrosis, lung injury, ageing, multiple sclerosis, liver cancer and melanoma.

Royal Veterinary College Royal College Street, London NW1 0TU, UK Tel: 020 7691 3560 Fax: 020 7681 9129 Email: business@rvc.ac.uk Website: www.rvc.ac.uk Contact: Dr Ken Larkin

70 | One Nucleus Directory 2017

The Royal Veterinary College is a world‑leading veterinary institution with an additional focus on comparative biomedicine and human health. Disciplines underpinning our research include pathology, epidemiology, biomechanics, genetics, public health and animal welfare. RVC Business co‑ordinates the provision of RVC’s commercial services, offering industry a combined package of state‑of‑the‑art laboratories and office space, contract research opportunities and access to specialist expertise and equipment. The college runs referral hospitals, diagnostic laboratories, and undertakes contract work from routine animal husbandry and laboratory services to full study and design management. We seek scientific partnerships with industry working in veterinary and human science.


Gold Members S

RxCelerate Ltd Moneta, Babraham Research Campus, Cambridge CB22 3AT, UK Email: info@rxcelerate.com Website: www.rxcelerate.com

RxCelerate is an outsourced drug development platform specialising in bespoke experimental design with data‑rich end‑points. We can drive your asset through drug discovery, medicinal chemistry, preclinical research and beyond, maximising your chances of reaching the clinic. RxCelerate offers comprehensive investigation packages and stand‑alone assays with in‑built flexibility, making it the perfect partner for both virtual, asset‑centric companies and large pharmaceutical companies seeking to outsource elements of their project. We combine client consultation with in‑house expertise to ensure that our in vitro design and preclinical models are robust and information rich, improving both compound progression and translational capacity.

Samanchia Ltd 30 Woodman Road, Brentwood CM14 5BE, UK Email: admin@samanchia.com Website: www.samanchia.com Contact: Stephen Reece

Samanchia is a limited company registered and based in Essex, UK, specialising in development of early stage disruptive medical technologies. The company is broadly based in preclinical and clinical product development in therapeutic and diagnostic areas.

Selcia Limited Fyfield Business and Research Park, Fyfield Road, Ongar, Essex CM5 0GS, UK Tel: 01277 367 000 Fax: 01277 367 099 Email: contact@selcia.com Website: www.selcia.com Contact: Dave Roberts

Selcia is a leading global CRO, specialising in 14C GMP radiolabelled API for clinical trials and in 14C custom radiolabelling for DMPK, dermal penetration and environmental fate studies. Selcia offers the full range of drug discovery services: integrated drug discovery, assay development, medicinal chemistry and ADME. With specialist expertise in macrocycles, natural products and their simplification and optimisation for drug use. Selcia has a unique peptidyl prolyl isomerase (PPIase) inhibitor screening platform. To support regulatory submissions, Selcia offers GLP analysis, including GLP NMR (500MHz), mass spectrometry, HPLC (analytical and preparative) and specialised purification capabilities from analytical (µg) to multi‑100g scale.

Shionogi Limited 33 Kingsway, London WC2B 6UF, UK Tel: 020 3053 4200 Website: www.shionogi.eu

At Shionogi Europe, we are committed to working differently and more closely with patients and the communities we serve. It is our ambition to be a leader in healthcare through the discovery and supply of medicines that offer the greatest level of satisfaction to patients, their families and healthcare providers, and improve quality of life. We are guided by a simple but powerful principle: follow the needs of the patient and the community that surrounds them, ensuring the real‑life challenges patients face remain the primary purpose behind R&D. We believe this is a more encouraging way to create clinically‑meaningful therapies.

www.onenucleus.com | 71


Gold Members S

Sinan Compass Limited Studio 2, Unit 6, Silverdale Enterprise Centre, Kents Lane, Silverdale, Newcastle‑under‑Lyme ST5 6SR, UK Website: www.sinancompass.co.uk

Sphere Medical Ltd Harston Mill, Harston, Cambridge CB22 7GG, UK Tel: 01223 875 222 Fax: 01223 875 284 Email: enquiries@spheremedical.com Website: www.spheremedical.com Contact: Gavin Troughton

Sphere Medical is a dynamic and growing company. Specialising in the development of innovative medical monitoring equipment. Our innovative products help in a range of medical situations. For blood gas monitoring, propofol sedation and total intravenous anaesthesia. This includes Proxima, an in‑line patient dedicated arterial blood gas analyser. A disposable micro analyser is integrated into the existing arterial line of the patient. To generate near real time analysis of blood gases, electrolytes and metabolites. All at the patient’s bedside, enabling faster clinical decision making and improved patient outcomes. We are also developing commercial partnerships with leading global medical device companies. Find out more about Sphere Medical at www.spheremedical.com.

Spirea Ltd 3 Warners Mill, Silks Way, Braintree CM7 3GB, UK

Stabilitech Ltd Unit 6, Sovereign Business Park, Albert Drive, Burgess Hill RH15 9TY, UK Tel: 01444 241 911 Email: elliot@stabilitech.com Website: www.stabilitech.com Contact: Elliot Bland

72 | One Nucleus Directory 2017

Stabilitech BioPharma is developing the next generation of viral vaccines and orally administered viral vectors. We have agreements with GlaxoSmithKline and Zoetis. Viral vaccines for injection: multistrain influenza – VZV (shingles) Platform technology stabilises viruses in liquid/lyophilised formulations at ambient temperature and above. Orally administered vectors for gene therapy/vaccination: biotherapeutic for metabolic indication; enzyme for biodefence applications; Zika vaccine platform technology allows repeat administration of viral vectors without development of viral vector immunity. Other programmes indications: GI inflammatory, GI oncology and orphan. Our technologies have broad additional applications including: oncolytic viruses – CRISPR/Cas9 viral vectors.


Gold Members T

STEMCELL Technologies UK Ltd Building 7100, Cambridge Research Park, Beach Drive, Waterbeach, Cambridge, Cambridgeshire CB25 9TL, UK Email: jo.kellet@stemcell.com Website: www.stemcell.com Contact: Jo Kellet

STEMCELL Technologies Inc. is a privately‑owned biotechnology company based in Vancouver that helps power leading‑edge life science research around the world. Scientists performing stem cell, immunology, cancer, regenerative medicine and cellular therapy research are among those who rely on our cell culture media, cell separation products, instruments, ancillary reagents and contract assay services. We create novel, useful, standardised products of unfailing quality and deliver them to more than 70 countries via our many regional offices. Driven by our love of science and our passion for quality, we see ourselves simply as ‘scientists helping scientists’.

Sunergos Innovations Nine Edinburgh BioQuarter, 9 Little France Road, Edinburgh EH16 4UX, UK Tel: 0131 651 7897 Email: enquiries@sunergosinnovations.com Website: www.sunergosinnovations.com Contact: Dr Mike Capaldi

Sunergos Innovations is a commercialisation catalyst that transforms innovative and disruptive research into genuine returns for entrepreneurs and our partners.

Talisman Therapeutics Ltd Jonas Webb Building, Babraham Research Campus, Cambridge CB22 3AT, UK Tel: 01223 804 070 Email: admin@talisman‑therapeutics.com Website: http://talisman‑therapeutics.com Contact: Dr E Scraggs

Talisman Therapeutics is a human stem cell drug discovery company, based in Cambridge, UK. We are committed to revolutionising the discovery of pharmacological treatments for Alzheimer’s disease (AD) initiation and progression. Our novel human stem cell models of AD provide a transformative platform for rapid and relevant compound identification, which significantly accelerates drug discovery. We work with other organisations on a collaborative basis, to maximise the impact of our own and their research and development activities. Partners include large pharmaceutical companies, small biotech businesses and universities.

Talking Medicines 202 Bath Street, Glasgow G2 4HW, UK Tel: 0141 352 9855 Email: info@talkingmedicines.com Website: www.talkingmedicines.com Contact: Elizabeth Fairley

Talking Medicines Limited develops products that bring medicines to life for the patient, empowering them to take their health into their own hands. Our mission is to create world class innovative global digital health solutions with societal and economic impact. Talking Medicines recently launched their big data solution, which facilitates self‑management and comorbidity across medicines, allowing healthcare customers to get insights into real world uses of medicines. Sales will accelerate product development across smart‑user devices, predictive analytics and international roll‑out. We are located in Glasgow and the Stevenage BioScience Catalyst – please get in touch with us to learn more.

www.onenucleus.com | 73


Gold Members T

TCRS The London Bioscience Innovation Centre, Royal College Street, London NW1 0NH, UK Tel: 020 7691 0987 Email: info@tcr‑solutions.com Website: www.tcr‑solutions.com Contact: Dr Peter MacLennan

Created by a team with in‑depth experience of the UK clinical research sector, TCRS provides a full range of clinical development services to pharmaceutical companies, biotechnology organisations and university academics. Our founders previously held senior posts within the NHS and academia making us uniquely qualified to offer guidance on the UK’s legislative framework. Whether you are seeking support for every aspect of your clinical research project or are looking to outsource just one part of a study, TCRS offers flexibility, momentum and value.

Thames Valley Science Park Whiteknights House, Whiteknights, Reading RG6 6AH, UK Tel: 0118 378 8978 Email: d.j.gillham@tvsp.co.uk Website: www.tvsp.co.uk Contact: David Gillham

Home to a lively community of ambitious, knowledge-based companies and located just off the M4 in Reading, close to Heathrow and London, TVSP offers serviced laboratories and modern, flexible office space in a relaxed, campus style environment and development plots and expertise for companies wanting to develop bespoke R&D or office buildings. Our 50 acre park is designed to facilitate connectivity and our approach is to tailor the right package to meet your evolving needs. Our close links with the University of Reading offers your business access to world-class talent and expertise in the heart of the Thames Valley.

The Milner Therapeutics Institute and Consortium University of Cambridge, Tennis Court Rd, Cambridge CB2 1QN, UK Tel: 01223 767 111 Email: info@milner.cam.ac.uk Website: www.milner.cam.ac.uk Contact: Kathryn Chapman

The Milner Therapeutics Institute is a global therapeutic alliance based at the University of Cambridge, dedicated to the conversion of basic science into therapies. Its mission is to foster close collaborative interactions between academic and industry to accelerate medical advances. The Institute represents a new ‘open borders’ paradigm, with no physical boundaries and a flexible operational model. The outreach programme consists of the Milner Therapeutics Consortium and the Affiliated Partnership Scheme which, together, include partnerships with 47 companies, the University of Cambridge, the Sanger Institute and the Babraham Institute.

The RSA Group The Gate House, 37 Fretherne Road, Welwyn Garden City AL8 6NS, UK Tel: 020 3818 8820 Email: hq@thersagroup.com Website: www.thersagroup.com Contact: Alex Bennett

74 | One Nucleus Directory 2017

The RSA Group is the pre‑eminent executive search firm in global life sciences. Providing a unique combination of executive search and executive interims, we deliver results through data driven due diligence. Our Proof of Candidate® approach is based on evidence and in‑depth comparative analysis, supporting clients to make better hiring decisions. Since 1981, our consultants have drawn on their wealth of executive search and industry experience to deliver a focused solution to our clients. Large enough to be global and small enough to remain local, we are where you are: Austria, Belgium, China, Germany, Singapore, Switzerland, Turkey, UK and USA.


Gold Members T

TopiVert Pharma Ltd Imperial Bioincubator, Level 1, Bessemer Building, London SW7 2BP, UK Tel: 020 3763 9468 Email: info@topivert.com Website: www.topivert.com

TopiVert Pharma Ltd is a private, clinical‑stage biotechnology company developing next generation, narrow spectrum kinase inhibitors (NSKIs) as novel, non‑systemic medicines for the treatment of chronic inflammatory diseases of the gastrointestinal tract and eye. Our most advanced drug candidate, TOP1288, is in phase 1 clinical development with data from both healthy volunteers and ulcerative colitis patients expected in H1 2016. In addition, clinical development of our lead ophthalmology compound, TOP1630, in dry eye disease is planned for late 2016. TopiVert is located at the Imperial College Bioincubator in London. The company was founded in 2011 and backed by blue‑chip investors.

Total Scientific Babraham Research Campus, Cambridge CB22 3AT, UK Tel: 01223 835 968 Email: info@totalscientific.com Website: www.totalscientific.com Contact: David Mosedale

Total Scientific is a contract research organisation with experience in all aspects of biomarker research, from biomarker identification using omics technology through assay design, development and validation to multi‑site clinical studies designed to validate or test biomarkers. However, in addition to these biomarker‑related activities we provide a wide range of laboratory services including Biacore, multiplex assays, enzyme and binding assays, data management and biostatistics. Our flexibility and bespoke approach means we are often the first CRO our clients turn to for something a bit different, whether that is plugging a gap in your project plan or a complete development project.

Transpharmation Ltd 2 Royal College Street, London NW1 0NH, UK Tel: 020 7691 0984 Email: mark.duxon@transpharmation.co.uk Website: www.transpharmation.co.uk

Spun out of GlaxoSmithKline Pharmaceuticals in 2010, Transpharmation was created to be a CRO with a difference; cross‑therapeutic area expertise in translational pharmacology from bench to bedside. Transpharmation is led by a team with years of proven hands‑on drug discovery and business expertise, noted for client and science‑focused relationships, across an extensive network in the pharmaceutical and biotechnology sectors. We have steadily built molecular biomarker expertise in preclinical and clinical samples of disease to support our existing therapeutic focus in AD, PD, treatment resistant depression, schizophrenia, epilepsy, sleep disorders, pharmacoEEG, cognitive disorders, pain and pharmacodynamic modelling.

Traxeus Pharma Services 2 Old Brompton Road, Suite 512, London SW7 3DQ, UK Tel: 07739 539 950 Email: info@traxeus.com Website: www.traxeus.com Contact: Marc Charron

Traxeus Pharma Services offers services primarily to UK/European biotech companies. We have in‑depth knowledge of the technical and regulatory requirements to develop and launch healthcare products. Our consultants have experience of working for both large pharma and small biotechs, as well as regulatory authorities. Our CMC consultancy services include ad hoc advice and management of outsourced formulation development, manufacturing and clinical trial supplies. We provide regulatory support to organisations developing and launching products in Europe and China. This includes expert review and submission writing. Our training courses cover both GxP and modern management techniques and can be adapted for in‑house requirements.

www.onenucleus.com | 75


Gold Members T

Twigkit 20 Station Road, Cambridge CB1 2JD, UK Tel: 01223 653 163 Email: hello@twigkit.com Contact: Stefan Olafsson

Twigkit’s software enables our customers to rapidly develop beautiful big data applications which allow them to access all their information, from any source, anywhere, and on any device. Our products help scientists, researchers and clinicians find answers and collaborate in a secure environment, by reducing the time and resources required to build fully customisable, elegant solutions. Proven within research, product development, drug discovery and clinical trials, Twigkit seamlessly and securely brings all your structured and unstructured data together, from multiple sources, in‑cloud or on‑premise.

TwistDx Ltd Minerva Building, Babraham Research Campus, Babraham, Cambridge, Cambridgeshire CB22 3AT, UK Tel: 01223 496 700 Email: a.mcelligott@twistdx.co.uk Website: www.twistdx.co.uk Contact: Abigail McElligott

TwistDx designs and manufactures Recombinase Polymerase Amplification or RPA, a multiplexable isothermal DNA/RNA amplification and detection technology that works amazingly fast. RPA is a portable alternative to PCR and is ideally suited to point‑of‑use molecular assays for digital, microfluidics, agriculture, veterinary and biodefense applications. Speed – detection within 15 minutes. Sensitivity – single molecule detection and no thermocyler needed. Simplicity – stable lyophilised reagents. Reliable isothermal technology with little or no hardware required. Read over 100 peer reviewed publications from users who are benefiting from the incredible speed, simplicity and portability of RPA: www.twistdx.co.uk/publications.

Valirx Plc 3rd Floor, 16 Upper Woburn Place, London WC1H 0BS, UK Tel: 020 3008 4416 Email: info@valirx.com Website: www.valirx.com Contact: Kumar Nawani

Valirx Plc is a biopharmaceutical company developing technologies and products in oncology therapeutics and diagnostics. Valirx has a focus on the novel treatments of cancers and associated biomarkers. Our technologies and products however can also be applied to the other fields as well, such as neurology and inflammatory diseases.

Vernalis Granta Park, Abington, Cambridge CB21 6GB, UK Tel: 0118 938 0000 Fax: 0118 938 0001 Email: corporatec@vernalis.com Website: www.vernalis.com

76 | One Nucleus Directory 2017

Vernalis is a commercial stage pharmaceutical company with three approved products: Tuzistra® XR, targeting the US prescription cough cold market; MOXATAG®, a once‑a‑day formulation of the antibiotic, amoxicillin, indicated for the treatment of tonsillitis and/or pharyngitis secondary to Streptococcus pyogenes; and frovatriptan for the acute treatment of migraine. The company also has four further prescription cough cold products under development with Tris and a broad pipeline of research and NCE development programmes. The company’s technologies and capabilities have been endorsed by collaborations with Asahi Kasei Pharma, Endo, Genentech, GSK, Lundbeck, Menarini, Novartis, Servier, Taisho and Tris.


Gold Members Z

Williamson Biotech Solutions 67, Chessel Avenue, Bitterne, Southampton SO19 4DY, UK Email: info@williamsonbiotechsolutions.com Website: www.williamsonbiotechsolutions.com Contact: Jeanne‑Françoise Williamson

Williamson Biotech Solutions offers operational business development and marketing services to help biotech, pharma and medtech companies take stronger market position. Our area of expertise focuses on strengthening your image, delivering clear messages to customers and investors with the aim to increase sales; on bringing fresh ideas to look at new market opportunities; and, finally, saving you time by doing the work on your behalf as an extension of your team. Williamson Biotech Solutions is also involved in supporting the bio‑entrepreneurship.

Xintera Ltd St John’s Innovation Centre, Cowley Road, Cambridge CB4 0WS, UK Tel: 07584 222 034 Website: www.xintera.com Contact: Koenraad Blot

Xintera Ltd provides customised solutions for customers seeking strategic advice and implementation in the areas of clinical development, regulatory and medical affairs or health economics and outcomes research. Our approach is synergistic and highly cross‑functional, with a broad network of international experts to enhance our core competencies.

Zyme Communications Ltd St John’s Innovation Centre, Cowley Road, Cambridge CB4 0WS, UK Tel: 01223 968 920 Email: info@zymecommunications.com Website: www.zymecommunications.com Contact: Lorna Cuddon

Zyme Communications Ltd (Zyme) provides PR and marketing services for the life science sector, supporting companies to raise their profile, build corporate value, and generate interest from commercial leads, investors and partners. Based in Cambridge and Manchester, UK, Zyme is focused on providing real value from objective‑led communications. Zyme has an experienced senior team who are specialists in life science PR and marketing and are ideally positioned to support clients to reach their target audiences, from bench scientist to decision‑maker, and small biotech to international pharma. www.zymecommunications.com.

www.onenucleus.com | 77


surgicaltools.co.uk will work with you to reduce business risks and implement business continuity plans We will provide business peace of mind and critical business risk impact assessment by: • Business process and function mapping • Risk mitigation and contingency planning • Testing crisis and disaster recovery plans • Providing training and workshops • Satisfying insurers business risks have been fully assessed

A world class research and development centre at the heart of the UK’s life sciences cluster BioPark offers you specialist laboratories, ready to use office space and conference facilities so that you can grow and develop your new products and technologies

30

Telephone: 01763 247681 Email: info@assetandsystems.co.uk www.assetandsystems.co.uk

Just minutes from

London by train

Call us on 01707 356100 or visit www.biopark.co.uk GA16473/??/12_16


One Nucleus

Silver Members


Silver Members 0

001 Limited 4 Cedar Court, Parkway, Porters Wood, St Albans, Hertfordshire AL3 6PA, UK Tel: 0845 389 2001 Fax: 0845 389 2002 Email: info@001ltd.co.uk Website: www.001ltd.co.uk Contact: Sunny Glasson

001 Limited specialises in auditing, purchasing, monitoring and providing advice to companies on electricity, gas and telecoms. Unlike competitors, our solution is not to try and change our clients’ contracts but to ensure that their current contracts are set up efficiently and they are being charged correctly. As well as this our historical auditing involves much more than just invoice validation. Our team are industry‑trained and so are well placed to spot any irregularities. We work on a no savings, no fee basis and can guarantee that you have nothing to lose by calling us for a free energy audit.

42 Technology Ltd Meadow Lane, St Ives, Cambs PE27 4LG, UK Tel: 01480 302 700 Fax: 01480 302 701 Email: answers@42technology.com Website: www.42technology.com

We are a successful and growing consultancy specialising in innovation, design and development. Our work with world‑leading clients in a range of industries takes products and processes from ideas to reality. We have built a reputation for challenging the status quo and finding creative and pragmatic solutions to difficult technical problems. Our life sciences team’s expertise spans microfluidics, thermal control, mechanisms and sensors, enabling us to help clients, ranging from start‑ups to global multinationals, to achieve their technological goals on time and on budget. Recent work has included development of surgical instruments, diagnostic equipment, drug delivery devices and telehealth systems.

A4PBio Innovation House, Discovery Park, Ramsgate Road, Sandwich, Kent CT13 9FF, UK Tel: 01304 249 106 Email: richard.hucker@a4pbio.com Website: www.a4pbio.com Contact: Richard Hucker

A4PBio provides CRO oversight, project management and consultancy services in bioanalysis and biologistics for the life science sector. A4PBio provides solutions in proactively managed transport of time and temperature critical biological samples, cell‑based therapies and dosing materials. Our expert management of bioanalytical projects includes the selection of providers, assay development and validation, study sample analysis, data reporting and document review. A4PBio’s client‑focused, flexible, scalable resources, based around our considerable pharmaceutical, biotechnology and CRO experience, deliver value‑added, cost‑effective, scientifically robust, and regulatory compliant outsourcing or consultancy solutions.

Abcodia Ltd The Network Building, 97 Tottenham Court Road, London W1T 4TP, UK Tel: 07870 904 709 Email: info@abcodia.com Website: www.abcodia.com Contact: Julie Barnes

Abcodia validates biomarkers for screening and early cancer detection. We have access to a longitudinal biobank derived from 202,000 initially healthy volunteers, 50,000 of whom donated serum annually. These volunteers have since developed numerous diseases and Abcodia works with diagnostic companies to validate their biomarkers. The unique aspect is that with our biobank, biomarker levels can be measured years before diagnosis, when patients are asymptomatic. Abcodia is a founding partner of the Early Diagnosis Consortium with CRUK and CRT. In addition to our validation collaborations, Abcodia has brought an ovarian cancer screening test (ROCA®) to the UK market in 2015.

Abingworth LLP 38 Jermyn Street, London SW1Y 6DN, UK Tel: 020 7534 1500 Fax: 020 7287 0480 Email: info@abingworth.com Website: www.abingworth.com

80 | One Nucleus Directory 2017

Abingworth is an international investment group dedicated to collaborating with life sciences entrepreneurs to develop their ideas into products that have a dramatic impact on health. With over $1 billion under management, Abingworth invests at all stages of development, from start‑ups to publicly traded companies, and across all life science sectors. Supporting its portfolio companies with a team of 27 at offices in London, Menlo Park (California) and Boston, Abingworth has invested in 142 life science companies, leading to 63 IPOs and 40 mergers and acquisitions.


Silver Members A

ABS Laboratories Ltd BioPark, Broadwater Road, Welwyn Garden City AL7 3AX, UK Tel: 01707 358 666 Fax: 01707 358 667 Email: abslabs@biopark.org.uk Website: www.abslabs.com Contact: Dr Mira V. Doig

ABS’ staff are experts at developing, validating and applying sophisticated techniques to quantify drugs, metabolites and biomarkers in biological fluids using LC‑MS/MS and multiplexed immunoassay using the Mesoscale technology platform. Our skills, experience and state‑of‑the‑art equipment mean that we can support a variety of studies, small and large, with a great attention to detail, customer service and turnaround times. We have GLP and GCP accreditation and a long list of validated methods in a variety of biological matrices, from plasma, urine and saliva to faeces, liver and even zebra fish brains.

Action for Innovation Ltd Lewis House, Great Chesterford Court, Great Chesterford CB10 1PF, UK Email: stephen@actionforinnovation.com Website: www.actionforinnovation.com

We can help you improve your internal and external innovation activities. We design and manage projects for: innovation strategy, opportunity analysis, technology evaluations and partnering strategies. We are experienced in cutting through complexity, creating shared understanding and coordinating effective action. Located in Cambridge, we run innovation projects worldwide, for healthcare, pharmaceuticals and biotech clients. Popular services in 2016 include: Innovation Audit – a diagnostic of the effectiveness of innovation in your organisation or department; and Project Review – make your projects more successful in future: what to sustain, what to improve, how to do it.

Agility Health Tech Stevenage Bioscience Catalyst, Gunnels Wood Road, Stevenage SG1 2FX, UK Email: info@agilityhealthtech.com Website: www.agilityhealthtech.com Contact: Claire Thompson

Advancing your products, raising your profile: consulting and communications for the healthcare and technology sectors. Technical: with over 25 years’ experience in the pharmaceutical, materials and nanotechnology sectors, we understand the complexities of developing and commercialising new technologies. We specialise in getting ideas from concept to market by supporting our clients in the following areas: product and formulation development; project, programme and CDMO management; and intellectual property analysis and identification. Strategic: choosing the right markets and partners is critical to the success of any organisation. We work with our clients to ensure they have the correct vision and strategy in place for their products, company and partnerships.

Air Liquide UK Ltd Station Road, Coleshill, Birmingham B46 1JY, UK Tel: 0800 637 737 Fax: 01675 467 022 Email: genenq.aluk@airliquide.com Website: www.uk.airliquide.com Contact: John Pritchard

Air Liquide UK Ltd, part of the world leading Air Liquide Group, provides your single source of expertise for the full range of industrial, laboratory, medical gases and related technologies. We are the preferred supplier for all laboratory gases, with attractive pricing for all Gold Members of One Nucleus. Air Liquide also offers: specialty gases in cylinders, pressure cans and lecture bottles; dry ice (Cardice®); industrial gases in cylinders; bulk carbon dioxide, bulk air gases (nitrogen, oxygen and argon) and engineering support services.

Air Products PLC 2 Millennium Gate, Westmere Drive, Crewe, Cheshire CW1 6AP, UK Tel: 0800 389 0202 / 0345 702 0202 Email: apukinfo@airproducts.com Website: www.airproducts.com Contact: Stephen Robinson

As a market leader in the life science sector, Air Products prides itself on our customer service and commitment to the market. With our competitive offer, we look forward to engaging with One Nucleus members to provide a cost effective solution for your requirements. Air Products enables customers in a myriad of industries to improve their environmental performance, product quality and productivity. With our strong knowledge of liquid nitrogen and our class‑leading range of Chart MVE freezers, we are able to provide the optimum turnkey solution to meet your needs, including comprehensive project management solution for the storage of your critical samples.

www.onenucleus.com | 81


Silver Members A

Alacrita London Bioscience Innovation Centre, 2 Royal College Street, London NW1 0NH, UK Tel: 020 7691 4915 Email: awalker@alacrita.com Website: www.alacritaconsulting.com Contact: Anthony Walker

Alacrita is a transatlantic pharma consulting firm providing services to the pharmaceutical, biotechnology, medtech, cell therapy and life science sectors. We wanted to take the best of traditional strategy consulting and freelancing to create a new consulting model. From traditional consulting, we took the calibre, professionalism and intellectual rigour of the world’s top firms, and from freelance consulting we took the benefits of years of experience in consulting and industry, commercial pragmatism and flexibility. We work across the spectrum of life sciences, from CMC to BLA, from manufacturing audits to payor and marketing strategy and from IP to valuations.

Albumedix Limited Castle Court, 59 Castle Boulevard, Nottingham NG7 1FD, UK Fax: 01159 551 299 Website: www.albumedix.com

Too many people battle with serious diseases that keep them from living a full life. Healthcare professionals work hard every day to provide these people with better health. Together with our partners, Albumedix develops and delivers albumin‑based drugs to improve therapies and enable more effective treatment. With better health comes an increased quality of life for patients, their families and the society in which they live. Albumedix is a global biopharmaceutical company and a fully owned subsidiary of Novozymes A/S.

Amadeus Capital Partners Limited Mount Pleasant House, 2 Mount Pleasant, Huntingdon Road, Cambridge, Cambridgeshire CB3 0RN, UK Tel: 01223 707 000 Fax: 01223 707 070 Email: psocha@amadeuscapital.com Website: www.amadeuscapital.com Contact: Pierre Socha

Amadeus Capital Partners is one of Europe’s leading technology venture capital firms, with some £500 million under management. Since its inception in 1997, the firm has backed over 80 companies in industries that include communications and networking hardware and software, cleantech, medtech, computer hardware and software, media, and e‑commerce. Major businesses built by the firm include CSR plc (LSE:CSR), the leading producer of single chip bluetooth radios for short range connections; and Solexa Ltd, the developer of next generation genetic analysis systems, merged into Illumina, Inc. (ILMN).

Amphora Research Systems Unit 6, Wokingham Commercial Centre, Molly Millars Lane, Wokingham, Berkshire RG41 2RF, UK Tel: 0845 230 0160 Fax: 0845 230 5160 Email: hello@amphora‑research.com Website: www.amphora‑research.com

Using a paper lab notebook? We’ve been releasing scientists from the tyranny of the paper lab notebook since 1996. Please do get in touch.

AMS Advanced Medical Services 26-28 Hammersmith Grove, London W6 7BA, UK Tel: 020 3751 1350 Fax: 020 3751 1351 Email: kathryn.hutchinson@ams‑europe.com Website: www.ams‑europe.com Contact: Kathryn Hutchinson

82 | One Nucleus Directory 2017

AMS Advanced Medical Services is a full service European focused clinical CRO. AMS specialises in the early clinical development of new molecules. Full regulatory consultancy services, access to bulk manufacturers and QPs, through to protocol development with key opinion leader access across all European markets. AMS understands the needs to deliver on time and on budget, and the impact that both of these will have on market funding focused companies. Clinical design services will allow for the maximising of potential for data from minimum patients, reaching the important go, no‑go quickly.


Silver Members A

AMS Biotechnology (Europe) Limited 184 Park Drive, Milton Park, Abingdon OX14 4SE, UK Tel: 01235 828 200 Fax: 01235 820 482 Email: info@amsbio.com Website: www.amsbio.com Contact: Alex Sim

AMS Biotechnology (AMSBIO) is recognised today as a leading company contributing to the acceleration of discovery through the provision of cutting‑edge life science technology, products and services for the medical, nutrition, cosmetics and energy industries. With in‑depth expertise in extracellular matrices, we provide solutions for studying cell motility, migration, invasion and proliferation. Acknowledged as experts in cell culture, AMSBIO partners with clients in tailoring cell systems to enhance organoid and spheroid screening. Custom services include stable cell line production, CRISPR/Cas9 genome editing, lentivirus and adenovirus production, large scale protein production and a comprehensive portfolio of antibody services.

Anabiotec Noorwegenstraat 4, B‑9940 Evergem, Oost‑Vlaanderen, Belgium Tel: +32 92 41 56 40 Email: lynn.vanschandevyl@anacura.com Website: www.anabiotec.com Contact: Lynn Van Schandevyl

Anabiotec offers a comprehensive analytical package for the pharma and biotech industry including (bio)pharmaceuticals and cell‑based products. By applying our analytical expertise in an operationally optimised and flexible manner, we ensure your data is ready at the right time and at the quality level you expect. Our GMP and ISO compliant facility offers: drug characterisation and identification; method development, validation and transfer; batch release testing; stability testing; and setup and testing for clinical trials (new). Through our joint venture with the Research Institute for Chromatography (‘anaRIC biologics’), our portfolio also covers non‑GMP solutions for biologics.

Antikor Biopharma Stevenage Bioscience Catalyst, Gunnels Wood Road, Stevenage, Herts SG1 2FX, UK Tel: 07711 580 914 Email: m.deonarain@antikor.co.uk Website: www.antikor.co.uk Contact: Dr Mahendra Deonarain

Antikor Biopharma is developing an antibody‑drug conjugation platform called OptiLink that enhances an antibody fragment’s ability to be chemically loaded with therapeutic drugs or imaging agents. This results in high drug loading, more favourable drug‑like properties and appropriate pharmacokinetics. Our ‘fast‑in, fast‑out’ approach to ADCs should result in a better therapeutic window, i.e retaining potency and reducing side effects. Our skills lie in antibody engineering and novel drug‑linker design/synthesis. Antikor is working with academic groups, biotech companies and pharmaceutical companies to add value to their technologies and is looking for further opportunities.

Apitope Technology (Bristol) Ltd Riverside Court, Beaufort Park, Chepstow NP16 5UH, UK Tel: 01291 635 511 Email: hayley.french@apitope.com Website: www.apitope.com Contact: Hayley French

Apitope develops peptide immunotherapies for the treatment of autoimmune diseases and anti‑drug antibodies. Apitope has a discovery platform that enables the selection of Apitopes (Antigen Processing Independent epiTOPEs). Apitopes selectively suppress abnormal immune responses and reinstate the normal immune balance. The company has generated a pipeline of seven programmes in clinical and preclinical development, of which the lead programme in multiple sclerosis is in phase 2. Apitope also has programmes in Graves’ disease, uveitis and FVIII intolerance.

APL Prismavägen 2, PO Box 5071, SE‑14175 Kungens Kurva, Sweden Tel: +46 10 447 960 0 Email: info@apl.se Website: www.apl.se/en Contact: Mattias Nyström

APL is a leading contract development and manufacturing organisation within Scandinavia. We have been established for over 30 years with four production sites in Sweden that offer services which cover the entire development process. We specialise in both sterile and non‑sterile manufacturing of biopharmaceuticals and pharmaceuticals, along with drug product formulation development and analytical method development. APL is highly flexible; we are also very dedicated to our customers and we can help you with a small project, right up to manufacturing your product. Our facilities are fully cGMP compliant and are regularly inspected by the EMA, FDA and customers corporate QA.

www.onenucleus.com | 83


Silver Members A

Aptuit (Oxford) Limited 111 Milton Park, Abingdon OX14 4RZ, UK Fax: +39 045 821 9111 Website: www.aptuit.com

Aptuit is a pharmaceutical services company that provides the most complete set of integrated early discovery to mid‑phase drug development solutions, by applying scientific excellence, outstanding service and a team of experienced scientific professionals. Aptuit’s broad range of integrated capabilities includes drug design and discovery, API development and manufacture, chemistry, manufacturing and controls, preclinical and IND enabling GLP/GMP programmes. Fully integrated services are available from our facilities in the UK, Italy and Switzerland where experienced scientists in multidisciplinary areas support pharmaceutical and biotech companies, providing also due diligence and consultancy services. For more information, visit www.aptuit.com.

Aptus Clinical Limited The Biohub at Alderley Park, Alderley Edge, Cheshire SK9 5BR, UK Tel: 01625 238 662 Email: jonathan@aptusclinical.com Website: www.aptusclinical.com Contact: Jonathan Lewis

Aptus Clinical is an expert in contract clinical research. Focusing on oncology, it was formed by three ex‑AstraZeneca colleagues with 75 years of combined industry experience and a mission to be a trusted partner for life science companies and academia. Through provision of bespoke clinical programme design and operational delivery excellence, our team of flexible, highly experienced drug development experts provide world class service to our clients. If you are looking for strategic input to study design or require flexible and cost‑effective study delivery, please get in touch. Aptus Clinical – expertise delivered flexibly.

Arithmos s.r.l Via Roveggia 122, I‑37135 Verona, Italy Tel: +39 045 585 492 Fax: +39 045 585 492 Email: info@arithmostech.com Website: www.arithmos‑ls.com Contact: Emilio Vandelli

Arithmos Life Sciences provides tailored IT solutions to optimise product value across all phases of the drug and device development process. Our solutions for the life science industry include GxP applications and services, computer system validation and IT compliance consultancy, clinical data visualisation and hosting. Arithmos has developed two proprietary software systems in‑house built to meet customer requirements: the Symphony EDC system and ArithmosCentrum PPM, a project and portfolio management tool, designed specifically for CROs. Arithmos is focused on quality services and the highest level of attention to security concerning customer data. We are an ISO 9001 and ISO 27001 certified company.

Artemida Pharma Stevenage Bioscience Catalyst, Gunnels Wood Road, Stevenage SG1 2FX, UK Tel: 0800 689 4391 Email: info@artemidapharma.com Website: www.artemidapharma.com

Artemida Pharma is a specialist consultancy business providing strategic drug development consultancy and project management to start‑up, biopharma and mid‑sized pharma companies. We provide comprehensive consultancy services, encompassing translational science including strategic clinical, CMC, regulatory, pharmacovigilance and commercial expertise. Our advice is independent and pragmatic. We work with our clients, complementing their skill‑sets and resources, to help them define and manage the optimum development pathway for therapeutic agents and devices.

Arthur J. Gallagher Life Science Team London The Walbrook Building, 25 Walbrook, London EC4N 8AW, UK Tel: 020 7234 4955 Email: david_baker@ajg.com Website: www.ajginternational.com Contact: David Baker

84 | One Nucleus Directory 2017

Arthur J. Gallagher is a leading international insurance and risk management advisory company with significant international reach and a global network that can offer client service capabilities in more than 140 countries, including national coverage throughout the UK. Our life science practice can combine local service with centralised technical expertise to access leading specialist insurers. We prepare comprehensive and competitive solutions to meet the risk profiles of our clients throughout their life cycle, from start‑ups through to multinationals. We are proud to be considered a trusted partner, having developed lasting relationships for more than 25 years.


Silver Members B

ASSM (Asset and Systems Support Management) 161 The Causeway, Bassingbourn, Royston, Hertfordshire SG8 5JD, UK Tel: 01763 247 681 Email: info@assetandsystems.co.uk Website: www.assetandsystems.co.uk Contact: John Moore

Business resilience and peace of mind for business. Working with small and medium size businesses to implement business continuity plans, risk mitigation, crisis management and disaster recovery planning. Business resilience workshops and training provided to businesses, together with management of business continuity programmes. Implementation of asset management systems, carrying out asset audits and full review of asset maintenance. Implementation of life cycle cost management systems for effective asset and equipment cost control and reduction.

Aston University – Research and Enterprise Office Research and Enterprise Office, Aston University, Aston Triangle, Birmingham B4 7ET, UK Tel: 0121 204 4242 Fax: 0121 204 4240 Email: reo@aston.ac.uk Website: www.aston.ac.uk/business Contact: Samera Karim

Aston University’s School of Life Sciences pursues interdisciplinary research in biomedical sciences, pharmacy, neurosciences, vision sciences, audiology and psychology at the interface between the laboratory and the clinic. The university also conducts research across schools through Aston’s Centre for Healthy Ageing. It addresses five themes: ageing metabolism, ageing eye, ageing mind, ageing and healing and ageing lives, to understand and prevent age‑related decline. Aston’s Brain Centre is an integrated research environment for the study of the brain and neurodevelopment in health and disease. It houses MEG (and a paediatric version is in development), 3‑tesla MRI, EEG and sleep research laboratories.

Autolus Limited Forest House, Depot Road, 58 Wood Lane, London W12 7RZ, UK Tel: 020 3829 6230 Email: contact@autolus.com Website: www.autolus.com

Autolus™ is a private biopharmaceutical company, focused on the development and commercialisation of engineered T‑cell immunotherapy products with extreme efficacy in the treatment of life‑threatening cancers.

Avacta Life Sciences Ltd Unit 20, Ash Way, Thorp Arch Estate, Wetherby LS23 7FA, UK Tel: 01904 217 046 Email: affimers@avacta.com Website: www.avactalifesciences.com

Avacta has developed Affimer® technology, an engineered alternative to antibodies. Based on a small protein, Affimer technology can be quickly developed to bind with high specificity and affinity to a wide range of targets. Affimer proteins can be developed as therapeutic molecules and can be used in a wide range of other life sciences applications in research and diagnostics.

Beauchamp Technology 7 Stockerston Road, Uppingham, Rutland LE15 9UD, UK Tel: 01572 823 267 Email: lkfenelon@gmail.com Contact: Lawrence Fenelon

Our main activities are: fundraising for early stage life science companies, helping companies become investment-ready; advice on obtaining R&D and SBRI grants; interim and financial management for early stage companies; and contributing to board decisions as a non‑executive director. Experience includes raising equity for eight life science companies and obtaining R&D grants for 16 others. We also have 12 years of experience of managing small companies and a number of non‑executive director posts. We can also assist with debt finance where banks are not willing to lend.

www.onenucleus.com | 85


Silver Members B

Bio‑Analysis Centre London Bioscience Innovation Centre, 2 Royal College Street, London NW1 0NH, UK Tel: 020 7691 2064 Email: imogen@b‑ac.co.uk Website: www.b‑ac.co.uk Contact: Imogen Lovera

The Bio‑Analysis Centre offers triple‑quad mass spectrometry and advanced HPLC. With these instruments we can assist in identifying and quantitating a wide range of analytes through contract research. In addition to providing an analytical service, we also offer training on the HPLC and LCMS. Once training has been completed, clients will be able to use our equipment to run their own samples.

BioBridge Limited 45 St Barnabas Road, Cambridge CB1 2BX, UK Tel: 01223 566 850 Email: mlloydevans@biobridge.co.uk Website: www.biobridge.co.uk Contact: Meredith Lloyd‑Evans

BioBridge® was founded in 1989 to address challenges to commercialisation for innovations in biosciences. We help our clients – public organisations, private companies and innovation‑generators – through the entire product chain, from discovery development to market entry and maintenance, including business‑to‑business and business‑to‑investors linkage. Our expertise is in all bioscience sectors. Current work includes product‑finding for pharmaceutical and dermocosmetic companies; EU‑funded projects on marine biodiscovery and Blue Growth socioeconomic indicators; mentoring start‑ups and young companies; and product safety and compliance oversight for a biomaterials company.

BioFrontline Ltd 51 Speed House, Barbican, London EC2Y 8AT, UK / 350 Third Street, Unit 2010, Kendall Square, Cambridge MA, USA Tel: +1 617 331 1885 Email: info@biofrontline.com Website: www.biofrontline.com Contact: Ronald Dorenbos

With locations in London and Boston, BioFrontline inspires and assists life science companies to achieve success by providing strategy, management and by identifying collaboration opportunities. For correspondence, please use ronalddorenbos@biofrontline.com or 350 Third Street, Unit 2010, Kendall Square, Cambridge, Massachusetts.

Bioline Reagents Ltd Unit 16, The Edge Business Centre, Humber Road, London NW2 6EW, UK Tel: 020 8830 5300 Fax: 020 8452 2822 Email: orders.uk@bioline.com Website: www.bioline.com/h_uk.asp Contact: Miles Collier

Founded in 1992 and headquartered in London, Bioline develops, manufactures and markets quality reagents to simplify, accelerate and improve life science research. Our mission is to provide customers with a range of products that are fast, easy to use and guaranteed to work, developed by scientists who understand science. At Bioline, we constantly strive to improve and deliver high quality products. We manufacture to ISO 13485 and ISO 9001:2008 quality standards. We welcome new business partners willing to grow with us. We have served the life science community for over 24 years and look forward to extending this to your business.

BioM Biotech Cluster Development GmbH Am Klopferspitz 19a, D‑82152 Martinsried, Munich, Germany Tel: +49 8989 9679 0 Fax: +49 8989 9679 79 Email: info@bio‑m.org Website: www.bio‑m.org Contact: Dr Stephanie Wehnelt

86 | One Nucleus Directory 2017

BioM Biotech Cluster Development GmbH is a not‑for‑profit organisation supporting the biotechnology sector in Bavaria and Munich, with a focus on personalised medicine. BioM promotes business interactions between regional and international companies, investors and other experts. BioM organises networking events and conferences, and offers services for international companies looking for biotechnology business partners in Bavaria. At www.bio‑m.org you will find news, company info and much more.


Silver Members B

BioNJ 1255 Whitehorse‑Mercerville Road, Building B, Suite 514, Trenton, New Jersey 08619, USA Email: dhart@bionj.org Website: www.bionj.org Contact: Debbie Hart

BioNJ, The Gateway to Health, is a network of more than 400 members representing research‑based life sciences companies and stakeholders dedicated to propelling a vibrant ecosystem where science is supported, companies are created, drugs are developed and patients are paramount. Because Patients Can’t Wait™, BioNJ supports its members in the discovery, development and commercialisation of therapies and cures that save and improve lives and lessen the burden of illness and disease on society by driving capital formation, fostering entrepreneurship, advocating for public policies that advance medical innovation, providing access to talent and education and offering a cost‑saving array of critical commercial resources.

Bionow Greenheys, Manchester Science Park, Pencroft Way, Manchester M15 6JJ, UK Tel: 07714 168 020 Email: info@bionow.co.uk Website: www.bionow.co.uk Contact: Helen Williams

An award‑winning specialist business development and services company serving the biomedical sector in the North of England. Our membership services add value and cost efficiency to scientific, clinical and business operations within early stage and growth‑oriented firms. We support business growth, competitiveness and innovation and offer an exceptional range of specialist business support products and services that focus upon the specific needs of companies at their individual stages of development. Our mission is to provide you with the tools and support for your organisation to become the most competitive in the industry through our range of specialist products and services.

BioPharmaLogic LLC St John’s Innovation Centre, Cowley Road, Cambridge CB4 0WS, UK Email: info@biopharmalogic.com Website: www.biopharmalogic.com Contact: Peter Bach

BioPharmaLogic Ltd expedites all aspects of non‑clinical development of new chemical and biological entities, re‑engineered products and advanced therapy medicinal products for start‑ups and SMEs. We play a key role in facilitating strategic planning, de‑risking development programmes, placing and monitoring studies, interpreting data, preparing regulatory documents and helping to ensure a seamless entry of products into first‑in‑human investigations. When things go wrong we also specialise in troubleshooting to minimise development disruption and maximise asset value. We regularly interact with agencies in Europe, North America and the Pacific Rim to facilitate cost‑effective and rapid progression of products through clinical development.

BioReliance Inc 4 Todd Campus, Glasgow G20 0XA, UK Tel: 07771 864 986 Email: des.cave@sial.com Website: www.bioreliance.com Contact: Desmond Cave

BioReliance is your global resource for specialty toxicology, with over 65 years of experience. We serve all industries, including: pharmaceutical, biotechnology, chemical, consumer product, medical device and academic organisations, providing the highest quality of customer experience and results. Our areas of expertise include complete and comprehensive genetic toxicology resources, with predictive screening, GLP regulatory assays, Tier II mechanistic assays and paradigms to follow up positive results. We are also the leading provider of transgenic carcinogenicity assessment, containing the largest historical database of tumour information for the rasH2 model.

BioRN Network Association Im Neuenheimer Feld 582, D‑69120 Heidelberg, Germany Tel: +49 6221 4305 111 Email: info@biorn.org Website: www.biorn.org

BioRN Network Association connects science and business. It promotes the development of the German Biotech Cluster Rhine‑Neckar (BioRN) into one of the leading life science clusters in Europe. The approximately 200 partners in the BioRN Cluster are biotech, pharmaceutical and healthcare enterprises and academic research and training facilities, as well as suppliers, branch‑specific service providers, communities, associations and also investors. Via the Health Axis Europe, BioRN Network is closely connected to Cambridge, Leuven, Maastricht and Copenhagen. The aim is to create a strong European alliance to initiate large pan‑European consortia between major players in health research and the healthcare industry.

www.onenucleus.com | 87


Silver Members B

Biosceptre UK Limited Jonas Webb Building, Babraham Research Campus, Babraham, Cambridge CB22 3AT, UK Tel: +61 4 1254 8824 Fax: 01223 496 069 Email: info@biosceptre.com Website: www.biosceptre.com Contact: Daniel Barton

Biosceptre has identified a novel cancer target, non‑functional P2X7 (nfP2X7) that is present in many types of cancer, but critically is not present in healthy tissue. Therapeutics directed to nfP2X7 have demonstrated the potential to treat cancer. Our lead candidates are: BIL010t, a topical therapeutic to treat basal cell carcinoma; BIL03s, a systemic monoclonal antibody to treat a variety of tumours; and BIL06v, a peptide‑based anticancer therapeutic vaccine. Concurrently, Biosceptre is also developing diagnostics to detect and monitor cancers. Biosceptre is now planning clinical trials that are expected to generate significant data validating the target nfP2X7 and the therapeutics in the Biosceptre pipeline.

BioStrata Marketing Compass House, Chivers Way, Vision Park, Histon CB24 9AD, UK Tel: 01223 253 787 Email: pavery@biostratamarketing.com Website: www.biostratamarketing.com Contact: Paul Avery

As a specialist marketing agency working in life science, our team is fluent in the languages of science and business. We combine PhD level knowledge with decades of marketing experience to develop integrated programmes that deliver results for life science companies. Everything we do starts with the development of a strategy that will help our clients succeed. As a truly integrated agency, we can then provide all of the tactical services required to help them realise their goals, from creative design and digital marketing through to content development, technical writing, social media and traditional PR tactics.

Biotrial International Limited Temple Chambers, 3‑7 Temple Avenue, London EC4Y 0HP, UK Email: contact@biotrial.co.uk Website: www.biotrial.com

Founded in 1989 and specialised in early development, Biotrial provides solutions from preclinical through to proof of concept development, bringing a wealth of expertise to the study design process. With locations in France, UK, Belgium, USA and Canada, Biotrial’s service lines includes non‑clinical pharmacology, phase 1, phase 2‑4/patient studies, bioanalytics, ECG, EEG and imaging core labs (QT/QTc trials, psychometric testing, and imaging), oncology, data management, statistics and medical writing. With 300 employees and 200 beds, Biotrial performs hundreds of clinical studies each year and offers tailormade solutions to pharmaceutical and biotech companies.

Black Swan Analysis Limited Moorbridge Court, 29‑41 Moorbridge Road, Maidenhead SL6 8LT, UK Tel: 01628 621 790 Email: christopher.ehinger@blackswan‑analysis.co.uk Website: www.blackswan‑analysis.co.uk Contact: Christopher Ehinger

Black Swan Analysis is well positioned to help any organisation in the healthcare industry analyse and determine the potential value of their assets. Whether it is a product with clinical data, or merely a fledgling concept, Black Swan can translate this information into a suitable format for both internal analysis and presentation to investors. We provide asset valuation services ranging from a summary report to a detailed business case. We also offer our proprietary Epiomic™ database (www.epiomic.com) that delivers a reliable and evidence‑based source of patient populations that goes beyond the basic prevalence rates to include patient attributes for each disease.

BOC The Priestley Centre, Surrey Research Park, Guildford, Surrey GU2 7XY, UK Tel: 0800 111 333 Email: jessica.thorpe@boc.com Website: www.boconline.co.uk Contact: Jessica Thorpe

88 | One Nucleus Directory 2017

BOC offers an unrivalled supply of high purity gases, gas mixtures, specialty gas equipment, liquefied gases, dry ice and bespoke applications to suit a wide range of applications and market sectors including research, analysis, calibration, process control and manufacturing. Our speciality gases can be customised to match your individual requirements. We hold a wide variety of common gas mixtures and high purity gases in stock around the UK, with 135 cylinder vehicles and 72 retail outlets, which means that BOC can offer unrivalled national coverage. Visit BOC at www. boconline.co.uk or call the BOC Speciality Gases department on 0800 020 800.


Silver Members B

Boult Wade Tennant CPC4, Capital Park, Cambridge Road, Cambridge CB21 5XE, UK Tel: 020 7430 7500 Fax: 020 7430 7600 Email: boult@boult.com Website: www.boult.com Contact: Matthew Spencer

Boult Wade Tennant is a specialist Patent and Trade Mark firm. We exist to help individuals and businesses protect, manage and enforce their intellectual property rights on a global scale. Our aim is simple – we aim to work with our clients, not just for them. This means we place emphasis not only on the quality of our work but also on the quality of the service we provide. Our award‑winning approach is down‑to‑earth and jargon‑free. Our attorneys are renowned for being committed to helping our clients succeed and for providing a service that is focused and aligned with our clients’ commercial objectives.

Bridge Partners Ltd Jefferys Building, St John’s Innovation Park, Cowley Road, Cambridge CB4 0DS, UK Tel: 01223 750 150 Email: info@bridgepartners.co.uk Website: www.bridgepartners.co.uk Contact: Alastair Mundell

When outsourcing IT support, you need a trusted partner who can integrate seamlessly with your own teams to get to know your business; someone who constantly exceeds expectations and designs high‑performance solutions according to your requirements. Bridge Partners, a reputable Cambridge IT support company with over 16 years’ experience, offers all this and more, whilst upholding our values: clarity, partnership and quality. Our professional, friendly team delivers tailored services, from hands‑on technical support to top‑level strategy. We work closely with you to shape, deliver and manage effective IT systems that work for your organisation, enhancing productivity and ensuring business continuity.

Bristows LLP 100 Victoria Embankment, London EC4Y 0DH, UK Tel: 020 7400 8000 Website: www.bristows.com Contact: Fiona Nicolson

Bristows is a full service law firm based in London with a history of working with innovative clients around the globe. Offering a true spectrum of legal expertise, the range of our contentious and non‑contentious experience enables us to advise on everything from the precedent‑setting to the purely procedural. Bristows is particularly well‑known for representing world leading life sciences organisations. Clients range from multinational pharmaceutical and biotech companies and medical device manufacturers to universities, SMEs and technology start‑ups. In providing tailored and practical advice, we combine our expertise across practice areas to form an integrated and market leading life sciences focus.

Brunswick IP Ltd 6 Brunswick Cottages, Midsummer Common, Cambridge CB5 8DL, UK Tel: 07904 547 643 Email: rbates@brunswickip.com Website: www.brunswickip.com

Brunswick IP provides pragmatic intellectual property advice to biotech, pharma and medtech businesses. We are UK and European patent attorneys. We work closely with select clients to provide a nimble, cost‑effective IP service, focused on commercial objectives, to best capture, protect and exploit intellectual property assets.

BTG International Ltd 5 Fleet Place, London EC4M 7RD, UK Tel: 020 7575 0000 Fax: 020 7575 0010 Email: info@btgplc.com Website: www.btgplc.com Contact: Chris Sampson

BTG is a growing international specialist healthcare company bringing to market innovative products in specialist areas of medicine to better serve doctors and their patients. We have a portfolio of interventional medicine products to advance the treatment of liver and kidney tumours, severe blood clots, varicose veins and advanced emphysema and specialty pharmaceuticals that help patients overexposed to certain medications or toxins. Inspired by patient and physician needs, BTG is investing to expand its portfolio to address some of today’s most complex healthcare challenges.

www.onenucleus.com | 89


Silver Members B

Bulb Interiors Ltd Unit 4, Priory Court, Wood Lane, Beech Hill, Reading, Berkshire RG7 2BJ, UK Tel: 01189 889 200 Email: info@bulbinteriors.com Website: www.bulbinteriors.com Contact: Dr Manisha Kulkarni

Bulb Interiors is an interior fit‑out specialists and offers workplace consultancy, building appraisals, interior design, furniture selection, project management and cost control. Our expertise produces inspiring results across the UK. Whether it be high‑tech laboratory or corporate office space – we pride ourselves on a professional service which is customised to suit you. We are proud to present our industry accreditations such as Constructionline, SafeContractor, JOSCAR (Accredited Supplier for Defence Industry), Quality Assurance – ISO 9001, ISO 14001. Bulb’s passionate and skilled team has a science specialist with several years of laboratory research experience.

Business France Haymarket House, 28‑29 Haymarket, London SW1Y 4SP, UK Tel: 020 7024 3664 Email: katie.docwra@businessfrance.fr Website: www.businessfrance.fr Contact: Katie Docwra

Business France is the French trade and investment body, founded by the French Government in 2015 following the merger of two separate agencies. Business France helps businesses to find commercial partners in target markets, paving the way for SMEs and mid‑size companies to sign trading agreements and generate sustainable export growth. For long‑term investment and growth both inside and outside France, we reach out to multinational companies with our expertise on investing in France. We are also responsible for the Créative France campaign, promoting France as an attractive location for business investment.

Cambrex UK & Eire Limited One Meadowlands Plaza, East Rutherford, New Jersey 07073, USA Website: www.cambrex.com

Cambrex is driven by passion. Our pharmaceutical products, expertise and technologies are accelerating small molecule therapeutics into the market to help businesses grow. Headquartered in New Jersey, USA, we have API development and contract manufacturing plants located in the USA and Europe. With over 35 years of manufacturing experience for both clinical and commercial APIs, all of our plants offer gram to multi‑ton quantities and include full analytical support. In the last two years alone, we have invested over $200 million to increase our API manufacturing capabilities and capacities. Our people are the experts customers enjoy working with.

Cambridge Employment Law LLP Stratford House, Ousden, Cambridgeshire CB8 8TN, UK Tel: 01223 656 952 Email: eleanor.freeman@cambridgeemploymentlaw.com Website: www.cambridgeemploymentlaw.com Contact: Eleanor Freeman

Awarded UK HR Regional Firm of the Year 2015 by the Legal 500, Cambridge Employment Law LLP is a small, specialist employment law practice, advising both employers and employees, embedded in the Cambridge market. Characterised by our size and specialist nature, all clients have a personal relationship with ‘stellar’ senior lawyers who understand their business and care about its success. Eleanor Freeman has a particular interest in the biomedical sector. Her familiarity with the common challenges facing start‑ups and high growth companies is balanced with significant experience representing global pharmaceuticals in all employment‑related matters.

Cambridge Healthcare and Biotech Ltd United Kingdom Tel: 01223 839 503 Email: info@chandb.com Website: www.chandb.com Contact: Martyn Postle

90 | One Nucleus Directory 2017

CH&B is a strategic advisor to life science companies throughout the world. It was founded in April 2003 by experienced professionals who have steered major products through all aspects of development and commercialisation. We bring a unique perspective through our expertise and in‑depth understanding of technology, product development, marketing, healthcare systems and corporate finance. The track record of our staff in deal‑making is second to none, enabling you to maximise value and minimise risk. We have also recently made available an iPad and iPhone version of our in‑house database, called the Directory of Healthcare and Biotech.


Silver Members C

Cambridge Network Limited The Entrepreneurship Centre, Hauser Forum, 3 Charles Babbage Road, Cambridge CB3 0GT, UK Tel: 01223 760 135 Email: membership@cambridgenetwork.co.uk Website: www.cambridgenetwork.co.uk

Cambridge Network is a membership organisation focused on bringing people together for shared success. With talent and expertise in abundance in this vibrant, world‑renowned high technology cluster, we want to attract people to join us and to promote the best that Cambridge can offer. We work with start‑ups, SMEs and multinationals to collaborate for shared success and to be better by: shared learning opportunities; operating a varied events schedule; offering cambridgenetwork.co.uk as a channel for members to promote themselves, their products/services and activities; working together to attract and retain talented employees; and providing a directory resource of business and academia.

Cambridgeshire Chambers of Commerce Endeavour House, Vision Park, Histon, Cambridge, Cambridgeshire CB24 9ZR, UK Tel: 01223 237 414 Fax: 01223 237 405 Email: enquiries@cambscci.co.uk Website: www.cambridgeshirechamber.co.uk Contact: John Bridge OBE DL

Cambridgeshire Chambers of Commerce is the county’s gateway to international trade, providing Cambridgeshire’s innovative exporters with the expert knowledge and business connections needed to capitalise on new market opportunities and succeed in our global marketplace. It’s not just international companies that benefit from our extensive membership package though, with businesses of all sectors and sizes joining our network to build new connections, extend their knowledge and influence key decision‑makers. With over 180 events a year, the Chamber offers a great many opportunities to stay informed, legally compliant and free to focus on what you do best – building your business.

Canadian High Commission Commercial/Economic Division, Canada House, Trafalgar Square, London SW1Y 5BJ, UK Tel: 07590 976 324 Email: amir.golbang@international.gc.ca Website: www.tradecommissioner.gc.ca/tradecommissioner-delegue-commercial/search-recherche. aspx?lang=eng Contact: Dr Amir Golbang

The Canadian Trade Commissioner Service (TCS) promotes trade between the UK and Canada and is able to provide you with on‑the‑ground intelligence and practical advice to help make better, more timely and cost‑effective decisions in order to achieve your international business goals.

Cancer Research Technology Ltd Angel Building, 407 St John Street, London EC1V 4AD, UK Tel: 020 3469 6300 Email: enquiries@cancertechnology.com Website: www.cancertechnology.com

Cancer Research Technology (CRT) is dedicated to advancing discoveries to beat cancer. We develop and commercialise exciting new discoveries in cancer research, working closely with leading clinical and academic institutions, pharmaceutical companies and biotechs worldwide. CRT facilitates the discovery, development and marketing of new cancer therapeutics, vaccines, diagnostics and enabling technologies. CRT is owned by Cancer Research UK, the world’s largest charitable funder of cancer research and we are uniquely placed to capitalise on the research and connections of our parent organisation.

Capella Bioscience Limited 158‑160 North Gower Street, London NW1 2ND, UK Tel: 020 7932 2136 Email: steve.holmes@capellabioscience.com Website: www.capellabioscience.com

Capella Bioscience discovers and develops therapeutic monoclonal antibodies (mAbs), both independently and in collaboration with biotechnology and academic partners. Our strategy is to use novel technologies to generate mAbs to innovative therapeutic targets in oncology and autoimmune disease. Our in‑house mAb pipeline maximises our technology’s application in the development of novel medicines.

www.onenucleus.com | 91


Silver Members C

Carmichael Fisher (Life Sciences) Tower 42, 25 Old Broad Street, London EC2N 1HQ, UK Tel: 020 3178 2630 Email: london@carmichaelfisher.com Website: www.carmichaelfisher.com/sector‑expertise/ life‑sciences Contact: Anke Janssen

Carmichael Fisher is an International executive search firm EMEA headquartered in London with offices in Brussels, Frankfurt, Hamburg, Stockholm, Lagos, Singapore, Dubai, Melbourne and Sydney. Our market leading multilingual Life Sciences Practice team conduct local and international cross‑border assignments with an integrated approach that transcends geographical boundaries whilst maintaining local sensitivities. Clients range from small local organisations to some of the largest brands and most highly respected international life sciences companies. Beyond executive search, we also provide market analysis projects, competitor intelligence, talent benchmarking and executive assessment.

Catalent Pharma Solutions Franklands Road, Blagrove, Swindon, Wiltshire SN5 8RU, UK Tel: 0800 8855 6178 Email: solutions@catalent.com Website: www.catalent.com Contact: Neil Jones

Catalent is the leading global provider of advanced delivery technologies and development solutions for drugs, biologics and consumer health products. With over 80 years serving the industry, Catalent employs approximately 9500 people, including over 1400 scientists, at more than 30 facilities across five continents. Catalent has proven expertise in bringing more products to market faster, enhancing product performance and ensuring reliable clinical and commercial product supply. As a leader in early phase development of prescription medicines, Catalent has been involved in nearly 50 per cent of all the new molecular entities to have received FDA approval in the past 10 years.

Charles River Chesterford Research Park, Little Chesterford, Saffron Walden CB10 1XL, UK Tel: +800 3195 3430 Email: askcharlesriver@crl.com Website: www.criver.com

Discovery from Charles River is industry‑proven in the successful development of novel therapies, with over 300 patents and 70 candidates delivered to our sponsors in the past 16 years. Backed by knowledgeable, experienced scientists, our comprehensive, integrated portfolio employs the latest technology and platforms to provide chemistry, biology, and pharmacology services that support clients from the earliest stages of hit identification all the way through to IND. Our client‑focused, collaborative approach creates true partnerships that anticipate challenges, overcome obstacles, and move us forward together on the journey of getting new drugs to market.

Charles Russell Speechlys LLP 5 Fleet Place, London EC4M 7RD, UK Tel: 020 7203 5000 Fax: 020 7203 0200 Website: www.charlesrussellspeechlys.com Contact: Jennifer Pierce

Charles Russell Speechlys is a city law firm with regional and overseas offices. It has a sector focus on technology in all forms, including life sciences. Our services include intellectual property, commercial, corporate, regulatory, tax, employment, real estate, reputation management and litigation. Clients include drug development companies, CROs, manufacturers, distributors, and suppliers of raw materials. We also regularly act for investors in the sector. We would be delighted to discuss specific projects or your needs in general.

Charnwood Campus Charnwood Campus, Summerpool Road, Loughborough, Leicestershire LE11 5RD, UK Website: www.charnwoodcampus.com Contact: Gosia Khrais

92 | One Nucleus Directory 2017

The Charnwood Campus is situated in the heart of the UK. This science, technology and enterprise park offers world‑class flexible laboratories, specialist manufacturing facilities, and small and large office space with a wide range of amenities, technical and clinical resources that meet the diverse needs of businesses from a variety of sectors. The campus is conveniently located on the outskirts of Loughborough. It benefits from excellent transport links: minutes away from the M1; nine miles away from East Midlands Airport (Europe’s largest freight airport); Midland Mainline railway route to London and other major UK cities.


Silver Members C

CIMYM BioSciences Ltd 59A Brent Street, London NW4 2EA, UK Tel: 020 8133 0442 Fax: 020 8203 9394 Email: yvonne@cimymbiosciences.com Website: www.cimymbiosciences.com Contact: Yvonne Joseph

CIMYM BioSciences was established to develop oncology and immunological therapeutics. At CIMYM we believe passionately that drug development can only be successful if it is patient centred: ’Begin with the patient in mind’. As a healthcare company we recognise an exceptional idea to fill a medical need, build a network and then establish a clinical utility that will improve patient care. CIMYM uses its expertise to manage value‑enhancing activities in the development process of pharmaceuticals and diagnostics. It takes a patient‑centred approach to co‑develop innovative products and in turn license the rights for manufacture and marketing to other pharmaceutical companies.

Cisbio Bioassays Parc Marcel Boiteux, BP 84175, F‑30200 Codolet, France Tel: 07894 556 884 Email: laffleck@cisbio.com Website: www.cisbio.com Contact: Louise Affleck

A partner dedicated to pharmaceutical research and in vitro diagnostics. Cisbio Bioassays is a global developer of products, technologies and services used in drug discovery, and a reference provider of immunoassays for in vitro diagnostics. HTRF®, its proprietary technology for life sciences, is a widely used assay platform by the pharmaceutical industry for drug discovery.

Clinical Network Services (CNS) Pty Ltd Level 4, 88 Jephson Street, Toowong, Brisbane, Queensland 4066, Australia Tel: +61 7 3719 6000 Email: cns@clinical.net.au Website: www.clinical.net.au Contact: Russell Neal / Paul Cronin

Clinical Network Services (CNS) is a uniquely integrated service group focused on product development, headquartered in Australia with offices in New Zealand, the UK and the USA. Through BioDesk we provide a comprehensive range of services in the strategic planning and delivery of CMC/non‑clinical development programmes, then, leveraging our extremely pragmatic regulatory environment, we can rapidly initiate phase 1 and 2 clinical trials in Australia/New Zealand.

Clinuvel (UK) Ltd Wesley House, Bull Hill, Leatherhead KT22 7AH, UK Tel: 01372 860 765 Email: mail@clinuvel.com Website: www.clinuvel.com

Clinuvel Pharmaceuticals is a global biopharmaceutical company focused on developing and delivering treatments for patients with a range of severe genetic and skin disorders. As pioneers in understanding the interaction of light and human biology, Clinuvel’s research and development has led to innovative treatments for patient populations with a clinical need for photoprotection and repigmentation. These patient groups range in size from 5000 to 45 million worldwide.

CN Bio Innovations BioPark Hertfordshire, Broadwater Road, Welwyn Garden City AL7 3AX, UK Tel: 01707 358 739 Email: enquiries@cn‑bio.com Website: www.cn‑bio.com

CN Bio Innovations develops human organ‑on‑a‑chip technologies: devices that enable the formation of miniature models of organs in the lab using living human cells. In 2016 we successfully showcased the world’s first 7‑organ‑on‑a‑chip platform. Over the past three years more than 25 pharmaceutical companies have used our devices to study the effects of drugs and other chemicals on organ function. CN Bio is also developing organ‑on‑a-chip models for specific diseases, including non‑alcoholic steatohepatitis and hepatitis B. CN Bio is a co‑recipient with MIT of a $26 million federal contract to develop next generation organs‑on‑chips and has also received InnovateUK grant awards.

www.onenucleus.com | 93


Silver Members C

Combebelle Life 168A Ashley Gardens, London SW1P 1PD, UK Tel: 07826 854 866 Email: patrickpkeohane@gmail.com Contact: Dr Patrick Keohane

BioPharma and life science development and commercialisation boutique consulting. Extensive experience in the USA, Japan and Europe. Specialist involvement in applications of artificial intelligence and machine learning in evaluation of preclinical and clinical scientific data.

Congenica Ltd Wellcome Genome Campus, Cambridge, Cambridgeshire CB10 1DR, UK Tel: 01223 499 965 Email: info@congenica.com Website: www.congenica.com

Congenica is a UK company founded on pioneering research from the Wellcome Trust Sanger Institute, NHS clinicians and regional genetic testing laboratories. We have translated this research into the gold standard clinical genomic analytics platform, Sapientia®, providing integration of human DNA sequences with deep clinical phenotyping, enabling clinicians to provide actionable interpretation of genetic disease for patients. Our platform is used by clinicians and researchers around the world for clinical diagnosis, prognosis and research. Many of the UK Regional Genetics Centres are using Sapientia as a decision support platform, in addition to clinical laboratories in other countries.

Consultant ‑ Carlos Pittol London, UK Tel: 020 7851 9080 Email: carlos.pittol@clubbcapital.co.uk

Biotechnology analyst and consultant.

Consultant ‑ Miranda Weston‑Smith St John’s Innovation Centre, Cowley Road, Cambridge CB4 0WS, UK Tel: 01223 511 664 Email: miranda@mws‑consulting.co.uk Website: www.mws‑consulting.co.uk

Miranda Weston‑Smith helps early stage biomedical businesses attract investment and develop their business strategy. She founded and runs BioBeat, a programme to inspire the next wave of bioentrepreneurs and business leaders. Miranda has a track record of commercialising early stage life sciences technology, and over 25 years of experience working with emerging technology businesses, advising on fundraising, new venture development and technology transfer. Miranda is a graduate in Natural Sciences, University of Cambridge and holds the Chartered Institute of Management Accountants Diploma in Management Accounting.

Consultant ‑ Nick Murrall Impington, Cambridge CB24 9YG, UK Tel: 07788 536 522 Email: nick.murrall@lifescipm.co.uk Website: www.lifescipm.co.uk

94 | One Nucleus Directory 2017

I provide specialist software project management consultancy for the life sciences, driving your projects forward – helping you achieve the ultimate goal of bringing effective therapies to market. I have an expert knowledge of software development project management combined with an in‑depth knowledge of the drug development pipeline, from discovery through development and clinical trials to post‑marketing, formed by working for many years in the industry. This means I can act as the perfect bridge between the scientists who use the software and developers producing it, including those offshore, ensuring that your projects are a success.


Silver Members C

Coutts Consulting Ashen House Farm, Doctors Lane, Ashen, Sudbury CO10 8JH, UK Email: Gordon@couttsconsulting.net Website: www.couttsconsulting.net

Coutts Consulting delivers practical solutions to complex problems in the private and public healthcare sectors. With three decades of international experience in the USA, Europe and Asia, we provide expert consultancy in: strategy and senior corporate council; leading change; strategic market access; market placement and optimisation. Our team has senior leadership experience across three continents, in large and small businesses in the private and public sector. They have held P&L responsibility for over £350 million organisations and have worked as advisory board members and as non‑executives for a variety of organisations and participated in national advisory bodies.

Covington and Burling LLP 265 Strand, London WC2R 1BH, UK Tel: 020 7067 2000 Fax: 020 7067 2222 Website: www.cov.com

Covington and Burling LLP maintains a global life sciences law practice, providing a full range of services to pharmaceutical, biotechnology, medical device, food and beverage, dietary supplement, veterinary, cosmetic, and agricultural companies. From our offices in Europe, the USA and Asia, together with a global network of specialist life sciences firms in key jurisdictions, we represent clients in connection with their formative transactions, critical disputes, and most vital regulatory matters. Our clients range from start‑up ventures and emerging companies, to major multinational corporations, as well as strategic investors and the leading industry trade associations.

CPI Biologics 1 Union Square, Central Park, Darlington DL1 1GL, UK Tel: 01325 376 800 Email: info@uk‑cpi.com Website: www.uk‑cpi.com

The Centre for Process Innovation (CPI) is a UK based technology innovation centre and the process arm of the High Value Manufacturing Catapult. Established to support the UK process manufacturing industry, CPI collaborates with universities, SMEs and large corporates to help overcome innovation challenges and develop next generation products and processes.

Creative Places LLP 3D Kings Parade, Cambridge, Cambridgeshire CB2 1SJ, UK Tel: 01223 359 840 Email: jonathan.burroughs@creativeplaces.com Website: www.creativeplaces.com Contact: Jonathan Burroughs

Creative Places is a property consultancy helping clients to create business environments that enhance innovation and enterprise. We work throughout the UK and, as well as acting for businesses, we work for many leading hospitals, universities and government establishments.

Crescendo Biologics Meditrina Building, Babraham Research Campus, Cambridge CB22 3AT, UK Tel: 01223 497 140 Fax: 01223 497 141 Email: info@crescendobiologics.com Website: www.crescendobiologics.com

Crescendo Biologics is a biopharmaceutical company discovering and developing potent, highly differentiated Humabody® VH therapeutics in oncology. Humabody® VH therapeutics are based on our proprietary, robust and highly efficient transgenic platform generating fully human VH domains with superior biophysical properties. We combine VH building blocks to create mono‑and multi‑specific Humabodies with novel formats, new mechanisms‑of‑action and differentiated pharmacological properties.

www.onenucleus.com | 95


Silver Members C

CW (Cambridge Wireless Ltd) c/o Central Working , Unit 6‑8, Cambridge Science Park, Cambridge, Cambridgeshire CB4 0FZ, UK Tel: 01223 967 101 Email: abhi.naha@cambridgewireless.co.uk Website: www.cambridgewireless.co.uk Contact: Abhi Naha

CW is the leading international community for companies involved in the research, development and application of wireless and mobile, internet, semiconductor and software technologies. With over 400 members, from major network operators and device manufacturers to innovative start‑ups, SMEs and universities, CW stimulates debate and collaboration via a colourful calendar of Special Interest Groups (SIGs) events. CW also organises major conferences and start‑up competitions along with other high‑quality industry networking events and dinners. For more information please visit www.cambridgewireless.co.uk.

Dehns St Bride’s House, 10 Salisbury Square, London EC4Y 8JD, UK Tel: 020 7632 7200 Fax: 020 7353 8895 Email: info@dehns.com Website: www.dehns.com Contact: Oliver Bonser

Dehns is one of Europe’s largest firms of patent attorneys. With a team of over 30 attorneys dedicated solely to the life sciences, healthcare and pharmaceutical sectors, our clients range from research institutes, universities, start‑ups and spin‑outs, through to SMEs and multinational corporations. Clients receive practical, strategic and commercial advice on all patent, trademark and design aspects, ranging from patenting innovative technologies to managing worldwide infringement conflicts, and from IP audits to IP strategy. With offices in London, Oxford, Cambridge, Manchester, Brighton, Sandwich and Munich, we have experts in your field who will help fully protect and commercialise your innovation.

Deliver Plus Limited 1 Spruce House, Durham Wharf Drive, Brentford Lock, Brentford, Middlesex TW8 8HR, UK Tel: 0845 500 1050 Email: sales@deliverplus.co.uk Website: www.deliverplus.co.uk Contact: Lyndsay Harrison / Roger Sumner Rivers

Deliver Plus offers both UK and international express courier delivery. Our healthcare division was established to meet the specialist needs of the biotechnology, pharmaceutical and clinical research industries. Our team of experts understands your specialist requirements and can help to ensure that your clinical trial operates to plan every time. Our managed service offers you a tailored, proactive service with a dedicated, named account manager assigned to your account. Through our global network of partners, Deliver Plus provides express delivery to over 220 countries worldwide and serves many major destinations. We can support cold storage and distribution of life science materials.

deltaDOT Limited London BioScience Innovation Centre, 2 Royal College Street, London NW1 0NH, UK Tel: 020 7691 2075 Website: www.deltadot.com Contact: Nigel Stokes

deltaDOT has developed an advanced High Performance Capillary Electrophoresis (HPCE) instrument. This new label free approach results in higher quality data (especially resolution and repeatability) at a fraction of the cost of conventional approaches. The data can often approach or surpass that produced by single quad MS in terms of resolution or quantitation. As well as selling our instruments, we are also looking for contract research, collaboration, licensing and distribution opportunities. Our technology is finding novel applications in virus quantitation/ characterisation, in QA/QC associated with antibodies, veterinary diagnostics and regenerative medicine.

DIT – East of England Region St John’s Innovation Centre, Cowley Road, Cambridge CB4 0WS, UK Tel: 0845 641 9955 Email: claire.lachlan@mobile.trade.gov.uk Website: www.gov.uk/dit Contact: Claire Lachlan

96 | One Nucleus Directory 2017

UK Trade & Investment (UKTI) was replaced by the Department for International Trade (DIT) in July 2016. DIT is responsible for promoting British trade across the world and ensuring that the UK takes advantage of the huge opportunities open to us. To find out how DIT helps UK businesses export and grow into global markets, please visit www.gov.uk/dit.


Silver Members D

DIT – London Region Department for International Trade – London Region, Newable, 10‑12 Queen Elizabeth Street, London SE1 2JN, UK Tel: 020 7234 3025 Email: chrisparsons@tradelondon.org.uk Website: www.gov.uk/dit

UK Trade & Investment (UKTI) was replaced by the Department for International Trade (DIT) in July 2016. DIT is responsible for promoting British trade across the world and ensuring that the UK takes advantage of the huge opportunities open to us. To find out how DIT helps UK businesses export and grow into global markets, please visit www.gov.uk/dit.

DLRC Ltd Exeter House, 1 Amor Way, Dunhams Lane, Letchworth Garden City SG6 1UG, UK Tel: 01462 372 472 Email: enquiries@dlrc.co.uk Website: www.dlrc.co.uk Contact: Dianne Lee

Strategic Expertise, Operational Excellence. A forward thinking regulatory affairs consultancy with over 300 years of experience, spanning many therapeutic specialities. We offer the full range of regulatory services, from strategic advice in early development, to compilation and management of regulatory submissions throughout the life cycle. Since 2005, we have helped companies of all sizes to maximise the commercial value of their products through innovative strategies. We understand the importance of a clear pathway to market which can maximise asset value when negotiating out‑licensing agreements, and our proactive collaborative interactions with regulatory authorities can improve chances of product approval in an optimal time.

Don Powell Associates Ltd 68 Woodland Road, Sawston, Cambridge CB22 3DU, UK Tel: 01223 515 436 Email: don@donpowellassociates.co.uk Website: www.donpowellassociates.co.uk Contact: Don Powell

Sometimes, telling the story of your science can be simple, but not all stories are easily told. Making sense of science is what Don Powell Associates do. We help you to develop effective media, PR, web and other communications in health, science or IT that build your company profile. With a background in research and 20 years’ experience delivering communications for projects from international programmes to focused studies, we understand your needs and can help you deliver the right messages to the right audiences.

Doubletree by Hilton Cambridge Granta Place, Mill Lane, Cambridge CB2 1RT, UK Tel: 01223 259 988 Fax: 01223 316 605 Email: avril.farr@hilton.com Website: www.doubletreecambridge.com Contact: Avril Farr

The DoubleTree by Hilton Cambridge is surrounded by the historic sights of Cambridge and is situated in an enviable position on the banks of the River Cam, boasting some of the best views Cambridge has to offer but only a few minutes’ walk from the centre of the city. With first class facilities for all occasions, business and pleasure, the hotel offers 122 contemporary bedrooms, a stylish Penthouse Suite, Marco Pierre White Steakhouse Bar and Grill, LivingWell health club and stylish conference rooms.

Dr Clare Sansom (Freelance) 19 Iver Close, Cherry Hinton, Cambridge CB1 3JG, UK Tel: 07957 451 176 Email: c.sansom@mail.cryst.bbk.ac.uk Contact: Dr Clare Sansom

I am a freelance consultant and a science and medical writer. I trained in physics before switching to biophysics for my PhD (later bioinformatics) and spent nine years as a postdoctorate in the UK and USA, before changing careers in 1998. I still teach to MSc level; bioinformatics and structural biology at Birkbeck, University of London and medicinal chemistry at the Open University. I write news and features in print and online for a specialist scientific and medical readership; provide specialist editing services; and offer support, training and capacity building in bioinformatics and related subjects within academia and industry.

www.onenucleus.com | 97


Silver Members E

EIP Fairfax House, 15 Fulwood Place, London WC1V 6HU, UK Tel: 020 7440 9510 Fax: 020 7440 9511 Email: mail@eip.com Website: www.eip.com

An integrated partnership of patent attorneys, trademark attorneys and solicitors, with offices in the UK, USA and Germany. EIP possesses in‑depth technical knowledge across the biotech, pharma and medical device fields. We offer one of the widest ranges of services of any intellectual property firm, including all aspects of obtaining and enforcing patents, trademarks and designs, with a team experienced in managing some of the biggest biotech and pharma patent cases. Our goal is to serve our clients effectively and efficiently by adapting our services to their priorities and by working successfully alongside their legal and technical teams.

Elkington and Fife LLP Thavies Inn House, 3‑4 Holborn Circus, London EC1N 2HA, UK Tel: 020 7936 8800 Fax: 020 7353 4329 Website: www.elkfife.com Contact: Oliver Kingsbury

Strong IP rights and freedom‑to‑operate (FTO) are vital to the success of many companies. We have a wealth of hands‑on experience in providing practical advice to clients to obtain and defend IP rights and establish FTO. We represent clients in the pharmaceutical, life science, medical device and food science sectors. Oliver Kingsbury and Gordon Wright worked in‑house for many years and both have extensive experience in drafting/prosecuting pharmaceutical patent applications, due diligence and FTO. Richard Gillard and Richard Cooke regularly represent patentees and opponents in EPO opposition and appeal proceedings. Chris McLeod is experienced in advising in trademark matters.

Embassy of Switzerland 16‑18 Montagu Place, London W1H 2BQ, UK Contact: Lutz‑Peter Berg

Switzerland is one of the strongest biotech/pharma countries in Europe with global pharma, mature biotech and innovative start‑ups, supported by world class research. The Embassy of Switzerland facilitates contacts to Swiss clusters for anyone interested in business or research partnerships.

EMBL‑EBI Wellcome Trust Genome Campus, Hinxton, Cambridge, Cambridgeshire CB10 1SD, UK Tel: 01223 494 444 Email: industry@ebi.ac.uk Website: www.ebi.ac.uk/industry Contact: Dominic Clark

The home for big data in biology. At EMBL‑EBI, we use bioinformatics – the science of storing, sharing and analysing biological data – to help people everywhere understand how living systems work and what makes them change. EMBL‑EBI provides freely available data from life science experiments, performs basic research in computational biology and offers an extensive user training programme, supporting researchers in academia and industry. The Industry Programme is a subscription based programme for interaction between EMBL‑EBI and major industrial life science research organisations that use our services.

Endomag Jeffreys Building, St John’s Innovation Park, Cowley Road, Cambridge CB4 0WS, UK Tel: 01223 652 540 Email: info@endomag.com Website: www.endomag.com

98 | One Nucleus Directory 2017

Endomag is a pioneer in the use of magnetism for minimally‑invasive surgical guidance. By addressing unmet needs in availability, affordability and workflow efficiency for surgical oncology, the company supports its mission to improve the global standard of cancer care for everyone, everywhere. Founded as a spin‑out from University College London (UCL) and the University of Houston in 2007, Endomag continues to develop its unique clinical platform that uses magnetic fields to power diagnostic and therapeutic devices.  The company has sales in over 30 countries worldwide and is headquartered in Cambridge, UK. For more information, please visit endomag.com.


Silver Members E

Entrepreneurs Fund Management LLP 4th Floor, Eagle House, 108‑110 Jermyn Street, London SW1Y 6EE, UK Website: www.entrepreneursfund.com

Entrepreneurs Fund is the venture capital member of COFRA, one of the world’s largest global family‑controlled group of businesses with a 170 year history. EF’s portfolio includes a number of innovative life sciences companies with disruptive technologies from diverse sectors, including biotechnology, medical devices, diagnostics and tools.

Epidarex Capital 20 Charlotte Square, 2nd Floor, Edinburgh EH2 4DF, UK Tel: 01312 433 700 Email: info@epidarex.com Website: www.epidarex.com Contact: Sinclair Dunlop

Epidarex Capital is an international venture capital firm which invests in early‑stage, high growth life science and health technology companies in under‑ventured markets within the UK and USA. Epidarex is actively investing in disruptive and innovative opportunities, many of which are from leading research universities in the UK.

ERA Consulting (UK) Ltd London Gas Museum, Twelvetrees Crescent, London E3 3JG, UK Email: info@eraconsulting.com Website: www.eraconsulting.com Contact: Adam Levy

ERA Consulting has served the biopharmaceutical industry for over 25 years, providing regulatory, strategic and technical guidance for the development of medicinal agents (>450 to date), including recombinant protein/antibody therapeutics, vaccines, ATMPs (cell/tissue/gene therapies), natural products and small molecules. Our consultants are drawn from biotech, pharma, biomanufacturing, regulatory, translational medicine and academic scientific backgrounds to provide experienced support from product inception through development to commercialisation. Services offered also include regulatory training and specialist due diligence. With offices in London, Washington D.C., Germany and Australia, ERA maintains a global presence and interacts closely with European, US and other regulatory authorities.

Eurofins CerepPanlabs 15 Research Park Drive, St Charles, MO 63304, USA Tel: +1 636 362 7082 Fax: +1 636 362 7131 Email: panlabsclientservices@eurofins.com Website: www.eurofinspanlabs.com Contact: Robin Leach

Eurofins CerepPanlabs Discovery Pharmacology business offers more than 1500 assays and models designed to increase the speed, precision and productivity of discovery research. Eurofins Pharma Discovery Services is committed to assisting clients achieve drug discovery success by providing comprehensive data and helping ‘tick the safety box’. We are the most experienced pharmacology service company, in continuous operation for over 40 years, while setting the benchmarks for quality, convenience, and expertise. Our legacy includes: concurrent controls run with every experiment, a historical database on assay performance, industry experienced professionals that assist in study design and data interpretation, and eCTD compatible data reports.

Euromedica Executive Search Ltd 5 Chancery Lane, City of London, London EC4A 1BL, UK Tel: 020 3440 5300 Fax: 020 3440 5301 Email: info@euromedica.com Website: www.euromedica.com

Euromedica provides retained executive search services of highest standards to the global life sciences industry. We are entirely focused on finding and placing the best leadership talent. Almost three decades of specialisation, a unique approach and over 3500 successful assignments make Euromedica an acknowledged global leader in executive search consulting for life sciences companies. From start‑ups to SMEs and major multinationals, our client base reflects the breadth of the life sciences ecosystem, including: pharmaceutical, medical device, biotechnology, diagnostic, digital health, laboratory instrumentation, convergent technology businesses, professional services consultancies, not for profit, generic/biosimilar, consumer and animal health organisations.

www.onenucleus.com | 99


Silver Members E

Europa Bioproducts Ltd 15‑17 North Street, Wicken, Ely, Cambridgeshire CB7 5XW, UK Tel: 01353 721 118 Fax: 01353 624 589 Email: info@europa‑bioproducts.com Website: www.europa‑bioproducts.com Contact: Michael Bannister

Europa Bioproducts is a distribution company that specialises in the supply of reagents and raw materials to the biopharmaceutical and diagnostic industries. We are the exclusive distributor for ProZyme Inc, which offers analytical services and manufactures a range of reagents used for glycan profiling and characterisation of therapeutic monoclonal antibodies and proteins. In 2016, we launched two new technologies for glycan analysis: GLY‑X with InstantPC for in depth characterisation by FLR and MS. Gly‑Q for rapid screening using capillary electrophoresis. Both technologies use our Gly‑X five minute digestion method with N‑Glycanase. We also supply products for diagnostic reagent kit manufacture.

Evolva Bio UK Ltd Newton Hall, Town Street, Newton, Cambridge CB22 7ZE, UK Tel: 01223 870 400 Email: contact@prosarix.com Website: www.prosarix.com

Evolva Bio UK Ltd (trading as Prosarix) is a biotech company whose core expertise involves in silico small molecule design and protein engineering applied to pharma and non‑pharma applications. It develops and utilises a proprietary computational platform and, in conjunction with industry leading software, has run many successful projects for third parties on an extensive range of protein targets involving a wide range of technologies and objectives. These include drug discovery projects (hit finding and lead optimisation), metabolic pathway prediction, protein engineering and the identification of novel uses for natural compounds. The company is wholly owned by Evolva SA. www.evolva.com.

Fahy Gurteen Laboratories 7300 Cambridge Research Park, Cambridge CB25 9TN, UK Tel: 07788 216 823 Email: sarojv@fglabs.com Website: www.fglabs.com Contact: Saroj Velamakanni

Fahy Gurteen Laboratories is a company specialising in cancer biomarker discovery, development and clinical validation. Fahy Gurteen Laboratories have secured worldwide patents for their novel multi‑parametric cell cycle cancer test, which has prognostic and predictive indications in breast, ovarian and lung cancer. Our research pipeline includes liquid biopsy based biomarkers for prognosis of breast and ovarian cancer. Fahy Gurteen Laboratories is also a molecular pathology service provider with the capability of providing a whole histopathology service from specimen grossing to reporting. With an extensive quality management system at the heart of everything we do, we supply an unparalleled service.

Fisher BioServices 1 Woodside, Bishop’s Stortford CM23 5RG, UK Tel: 01279 713 320 Fax: 01279 713 329 Email: dave.wilson@thermofisher.com Website: www.fisherbioservices.com Contact: Dave Wilson

Fisher BioServices is a leader in critical biological materials management. We are helping clients worldwide with everything from biobanking precious samples, to mitigation processes of storing finished products and API, to master and working cell banks. Fisher BioServices also provides comprehensive clinical trial supply chain management services including import, storage, packaging, labelling and QP release for low temperature and cryogenic cell/gene therapy products. Biobanking services include ambient to cryogenic storage, inventory management, biological specimen collection kit assembly, laboratory services including aliquoting, blood fractionation and PBMC/DNA/RNA extraction. Logistics services include global ultra cold chain transport and relocation.

Fisher Scientific UK Bishop Meadow Road, Loughborough LE11 5RG, UK Tel: 01509 555 500 Email: fisheruk.customerservice@thermofisher.com Website: www.fisher.co.uk Contact: Joanne Sharpe

100 | One Nucleus Directory 2017

Thermo Fisher Scientific Inc. (NYSE: TMO) is the world leader in serving science. Our mission is to enable our customers to make the world healthier, cleaner and safer. We serve customers within pharmaceutical and biotech companies, hospitals and clinical diagnostic labs, universities, research institutions and government agencies. We create value through our key brands – Thermo Scientific, Fisher Scientific, Invitrogen, Applied Biosystems and Unity Lab Services – offering a unique combination of continuous technology development and convenient purchasing channels, backed by large stockholdings, sophisticated distribution systems and through-life service capability.


Innovative Solutions and Services for the Biopharmaceutical and Diagnostic Industries • Tools for Glycan Analysis • Bovine Serum Albumins • Phycobiliproteins and Conjugates • Diagnostic Raw Materials For further details: Europa Bioproducts Ltd, 15-17 North Street Wicken, Ely, Cambridgeshire CB7 5XW www.europa-bioproducts.com

+44 (0)1353 721118 12862EUR~ProzymeAdvert(186x134).indd 1

21/12/2016 11:33

Assay and Service Solutions for Life Sciences

IO

N IS EV

E Y TH

ING

INTERA

T

R

C

GPCRs Cell signalling Biomarkers Epigenetics Protein:protein interactions

For more information: +44 7894 556 884 laffleck@cisbio.com

www.cisbio.com


Silver Members F

FluidX Ltd Northbank, Irlam, Manchester M44 5AY, UK Tel: 01625 861 614 Fax: 01625 861 615 Email: info@fluidx.eu Website: www.fluidx.eu Contact: Nina Markillie

FluidX – sample storage and tracking experts. 2D barcoded sample storage tubes, 2D tube tracking systems and processing instrumentation. 2D sample storage tubes – from 200ul to 10ml in SBS format rack design including 384, 96, 48 and 24 well. Also 10x10 and 9x9 solutions for RT and LN2. Sample tracking – large range of 2D and 1D barcode readers for single tube to full rack scanning. Processing instruments – automated tube de‑capping and re‑capping for screw and septum caps. Automated tube labelling, direct printing and application. Automated tube filler used in conjunction with a screw cap de‑capper/re-capper.

Fluorochem Limited Unit 14, Graphite Way, Hadfield SK13 1QH, UK Tel: 01457 860 111 Email: leej@fluorochem.co.uk Website: www.fluorochem.co.uk Contact: Lee Jones

Fluorochem has been supplying intermediates for research and development to pharmaceutical companies, universities, biotechnology companies and contract research organisations for over 40 years. The product portfolio of nearly 200,000 items includes fluorinated products, heterocyclics, boronic acids, sulphur compounds, novel organics, organometallics, silanes, siloxanes, biochemicals, NMR solvents, NMR tubes, Silicagel for chromatography and TLC plates.

GE Healthcare Amersham Place, Little Chalfont, Buckinghamshire HP7 9NA, UK Tel: 0870 850 4588 Email: onenucleus@ge.com Website: www.gelifesciences.com Contact: Laura Randall

GE Healthcare Life Sciences, a division of GE Healthcare, provides expertise and tools for a wide range of applications, including basic research of cells and proteins, drug discovery research, as well as tools to support large‑scale manufacturing of biopharmaceuticals. GE Healthcare Life Sciences also offers Smart Asset Management Services (SAMS), award‑winning solutions to keep your facility running smoothly. The SAMS programme offers total asset management services corrective and preventative maintenance capabilities for a comprehensive set of analytical technologies, delivered by dedicated GE engineers with a global sourcing function for locating parts and consumables from almost any vendor.

Gensler Aldgate House, 33 Aldgate High Street, London EC3N 1AH, UK Website: www.gensler.com

George James Ltd Hotley Bottom Barn, Hotley Bottom Lane, Great Missenden, Buckinghamshire HP16 9PL, UK Tel: 01494 867 655 Email: bridget.williamson@georgejamesltd.co.uk Website: www.georgejamesltd.co.uk Contact: Neil Burns

102 | One Nucleus Directory 2017

At George James Ltd we provide our clients with quality candidate shortlists via flexible recruitment services customised to individual needs. We also specialise in the behavioural development of teams and individuals via both open and bespoke training courses. A range of business development services are also provided, including fundraising, acquisition profiling and company/technology sale. Set up by senior, successful industry professionals, we will be pleased to review any potential needs and to provide best advice on possible solutions, whether this includes our services or not.


Silver Members G

Gerard Daniels UK Level 2, High Holborn House, 49‑51 Bedford Row, London WC1R 4LR, UK Website: www.gerard‑daniels.com

Gilson UK 20 Charles Street, Luton, Bedfordshire LU2 0EB, UK Tel: 0845 519 6872 Fax: 0845 519 6874 Email: info@gilsonuk.com Website: www.gilsonuk.com

Gilson provides high quality, dependable solutions for demanding liquid chromatography, solid phase extraction, liquid handling and gel permeation chromatography. From the legendary PIPETMAN pipettes, PIPETMAX low cost automated liquid handling platform to a full range of system solutions, Gilson is the element of purification for your laboratory. Our primary focus is on purifying samples via preparative HPLC, automated SPE or through GPC clean‑up. Gilson focuses on early drug discovery and development with our preparative HPLC systems. Gilson’s automated SPE systems and GPC clean‑up systems support environmental, food and beverage, and clinical and forensic markets, performing a wide variety of clean‑up applications.

Glass Box Thinking 18 Templewood, Welwyn Garden City AL8 7HX, UK Tel: 07780 957 492 Email: mark@glassboxthinking.co.uk Website: www.glassboxthinking.co.uk Contact: Mark Thomas

If you are pitching for new business, presenting to teams or speaking at conferences, coming across as confident, credible and engaging are skills all speakers need. Yet few presenters seek out expert help to overcome their fear of public speaking. Instead they rely on luck or a close circle of colleagues for feedback. It’s no wonder many reputations and business opportunities have been lost by poorly prepared presentations. I coach scientists, medics and business leaders to deliver engaging and persuasive presentations. If you want to change how you present then contact me and book a complimentary strategic session now.

Gowling WLG 4 More London Riverside, London SE1 2AU, UK Tel: 0370 903 1000 Email: luke.kempton@gowlingwlg.com Website: www.gowlingwlg.com Contact: Dr Luke Kempton

Gowling WLG is a new international law firm created by Gowlings and Wragge Lawrence Graham & Co. With more than 1400 legal professionals across 18 cities worldwide, we are positioned to help you rise to the challenges you face. In life sciences, our global team of just under 200 experts are market leading innovators providing in‑depth knowledge, practical insight and advice to a global client base. Immersed in the sector, many of the team have postgraduate science degrees and/ or have spent time in their careers as scientists. This hands‑on experience means that they understand your commercial needs and challenges.

Grove Lodge Consulting Ltd Grove Lodge, Preston Hill, Wingham, Kent CT3 1DB, UK Tel: 01227 728 621 Email: jeff@grovelodgeconsulting.com Website: www.grovelodgeconsulting.com Contact: Jeff Duke

Jeff Duke provides CMC consultancy services to the pharmaceutical industry. Jeff has over 20 years’ senior experience with Pfizer in a wide variety of roles within CMC functions and now consults globally on CMC matters. Areas of support include: CMC strategy, finding and working with CROs to ensure development and delivery of your API, formulations and analytical methods, ensuring your approach meets regulatory guidelines, risk assessment and quality by design, technology transfer to/from CROs, troubleshooting your CMC issues and staff training and awareness in CMC areas.

www.onenucleus.com | 103


Silver Members G

Grundon Waste Management Limited Clinical Operations, Star Works, Star Lane, Knowl Hill, Berkshire RG10 9XY, UK Tel: 01628 501 591 Fax: 01628 828 297 Email: phillip.steer@grundon.com Website: www.grundon.com Contact: Becky Lillywhite / Phil Steer

Grundon is one of the UK’s leading suppliers of integrated waste management and environmental solutions, working in partnership with customers to help minimise the financial and environmental impacts of their waste. We provide a total waste management solution for the reduction, reuse, recycling, recovery and disposal of waste, delivered by a combination of specialist services, contract management and the operation of our own facilities. Our service offer includes segregated collections of mixed recyclables, food, lab, pharmaceutical, anatomical, chemical, biological, genetically modified and radioactive waste with all collections carried out on our fleet of carbon neutral certified vehicles.

Guy’s & St Thomas’ NHS Foundation Trust Commercial Services Commercial Directorate, Guy’s Hospital, Great Maze Pond, 1st Floor Chapel House, London SE1 9RT, UK Website: www.gsttcommercialservices.co.uk Contact: Dr Terry Parlett

GSTT is one of the largest and oldest hospital trusts in the country and comprises Guy’s and St Thomas’ Hospitals, Evelina London Children’s Hospital and local community services. The IP & Commercial Research Unit supports commercial and healthcare related partnerships and activities between the Trust and industry, SMEs and charities internationally. The unit supports commercial research collaborations, contract research, knowledge transfer and consultancy activities, material transfers, product evaluation services, product development collaborations, technology transfer of GSTT discoveries and inventions (licensing opportunities, company and joint venture formations) and encourages engagement with industry. More information and contact details are available at www.gsttcommercialservices.co.uk.

Harlow Council Civic Centre, The Water Gardens, Harlow, Essex CM20 1WG, UK Tel: 01279 446 410 Email: andrew.bramidge@harlow.gov.uk Website: www.harlowez.org.uk Contact: Andrew Bramidge

Harlow Science Park will provide a vibrant new business hub where people can work, form partnerships and exchange ideas, creating an environment for innovation and collaboration. Within the Harlow Enterprise Zone, benefits include: high technology employment space, premium architect designed office space, business rates discounts, simplified planning, access to superfast broadband and networking at the M11 Health Enterprise Forum. Harlow will be the location for Public Health England’s HQ and national science hub. Harlow is uniquely located between London and Cambridge: five minutes from M11 junction 7, London is 35 minutes by rail, Stansted Airport is 20 minutes. Go to www.harlowez.org.uk and www.harlowbusiness.com.

Harts Business Solutions Hart House, Shire Hill, Thaxted Road, Saffron Walden, Essex CB11 3AQ, UK Tel: 01799 500 100 Fax: 0800 387 598 Email: sharon@harts1836.co.uk Website: www.hartsdirect.co.uk Contact: Sharon Hayes

Harts provides a comprehensive single‑source business solution for all One Nucleus members. Harts is a long‑established company with an excellent reputation – built on competitive pricing together with fast, professional, yet personal, customer service. Value‑added services include ‘try‑before‑you‑buy’ office seating, office refurbishments, project management, space planning, print management, in‑house design and print service, business gifts, audio‑visual products, PAT testing, PPE products and shredding, both on‑ and off‑site. Additional membership benefits include core contract price lists for office supplies (up to 80 per cent off RRP), other discounts up to 70 per cent off RRP.

Haseltine Lake LLP Redcliff Quay, 120 Redcliff Street, Bristol BS1 6HU, UK Tel: 01179 103 200 Fax: 01179 103 201 Email: hl@haseltinelake.com Website: www.haseltinelake.com Contact: David Hammond

104 | One Nucleus Directory 2017

Haseltine Lake is one of the largest independent IP firms in Europe. All of our resources and expertise are exclusively dedicated to IP protection, safeguarding the inventions, designs, brand identities and other innovations of our clients. We are privileged to work with some of the most exciting and forward‑looking businesses in the world. Our clients are at the forefront of innovation and product development in their fields and range from large‑scale international corporations to small start‑up companies. We work with many European, US, Japanese and Chinese businesses and with a network of specialist intellectual property attorneys throughout the world.


Providing commercial and network benefits of a location with direct access to Cambridge and London.

www.investessex.co.uk

Chesterford Research Park

Why an increasing number of life sciences companies are making Essex their UK location of choice… Reduced costs Diverse technology competencies Excellent connectivity Supply of talent

RESEARCH-TO-REVENUE Our unique combination of flexible accomodation combined with access to skills, services and equipment can add value to your business and deliver competitive advantage and growth.

Business Support Business rates discounts available

On-site services and equipment

01603 673673 www.norwichresearchpark.com Half page ad One Nucleus Directory 2017_V6.indd 1

Shared office & bench space with access to shared equipment lab

• •

Office & laboratory units from 13 sq m (140 sq ft) Serviced plots for development

• •

Free business coaching & mentoring Angel networking & grant signposting

• • •

Clinical Trials & Biorepository NMR & Bioimaging Genomics & Bioinformatics

10/01/2017 12:14:58


LABORATORY DESIGN AND BUILD SOLUTIONS

01223 894833

SALES@INTERFOCUS.CO.UK

MYNEWLAB.COM

Global Regulatory Consulting Your partner in Product Development

• Scientific and clinical consulting • Pre and post-approval regulatory services • Document management and publishing For more information please contact us at info@incresearch.com or call us at +44 7703 749463

incresearch.com/consulting


Silver Members H

HC Pharma Consultancy Limited 8 Dukes Wood Drive, Gerrards Cross SL9 7LP, UK Tel: 07836 317 128 Fax: 01753 627 701 Email: helen.cohen@hcpharma.co.uk Website: www.hcpharma.co.uk

Freelance consultancy on a daily or even hourly rate. HC Pharma Consultancy supports biotech/pharma for all partnering activities including licences, acquisitions and the management of strategic alliances. Specialisation in CNS and endocrinology, but able to support most therapeutic areas. Helen Cohen, founding director, has a successful track record in identifying and delivering value generating opportunities. With more than 30 years’ experience in clinical development, regulatory affairs, project management and business development, Helen is able to work closely with your team to build value before, during and after the partnering process.

Health Enterprise East Milton Hall, Ely Road, Milton, Cambridge, Cambridgeshire CB24 6WZ, UK Tel: 01223 928 040 Email: enquiries@hee.co.uk Website: www.hee.co.uk

Based at Milton Hall, Cambridge, Health Enterprise East delivers technology advisory services and innovation management to the industry and the NHS. Services are tailored to meet the requirements of each client, helping to address the challenges faced along the product development pathway, from strategic market analysis to practical advice and stakeholder insight. Our experienced team works with NHS organisations nationally and medtech globally; we are a trusted partner in realising innovation.

Healx Ltd St John’s Innovation Centre, Cowley Road, Cambridge CB4 0WS, UK Tel: 01223 560 848 Email: info@healx.io Website: www.healx.io

At Healx, we are passionate about finding new therapeutic solutions for patients with rare diseases. We believe that repurposing approved treatments is a cheap and effective way to improve quality of life of rare disease patients today.

Heptares Therapeutics Ltd Biopark, Broadwater Road, Welwyn Garden City AL7 3AX, UK Email: barry.kenny@heptares.com Website: www.heptares.com

Heptares is a clinical‑stage company creating novel medicines targeting G protein‑coupled receptors (GPCRs), a superfamily of receptors linked to a wide range of human diseases. Our proprietary structure‑based drug design platform has enabled us to build an exciting pipeline of new medicines with potential to transform the treatment of Alzheimer’s disease, schizophrenia, migraine, addiction, metabolic disease and other indications. Our ability to address highly validated, yet historically undruggable GPCRs has also attracted multiple partners including AstraZeneca, Takeda, Morphosys, Teva, Allergan and Kymab. Heptares is a wholly owned subsidiary of Sosei Group Corporation.

High Force Research Ltd Bowburn North Industrial Estate, Bowburn DH6 5PF, UK Tel: 01913 779 098 Fax: 01913 779 099 Email: stellajames@highforceresearch.com Website: www.highforceresearch.com Contact: Dr Stella James

High Force Research specialises in chemical synthesis and R&D and offers chemistry built on over 25 years of experience in developing and scaling up of complex syntheses of molecules for application in a wide range of end uses. We have state‑of‑the‑art purpose built laboratories in the UK and are MHRA certified. We provide a confidential, high quality service to the pharmaceutical, biotech, agrochemical and fine chemical industries including: chemical R&D, process development, contract synthesis, scale‑up, traceable manufacture, GMP manufacture and analysis. Our clients include multinationals, specialist discovery, virtual, start‑up and diagnostics companies from around the world.

www.onenucleus.com | 107


Silver Members H

Highbury Regulatory Science Limited 108 Eaststand, Highbury Stadium Square, London N5 1FF, UK Email: bobclay@highburyregsci.com Website: www.highburyregsci.com

Highbury Regulatory Science provides bespoke strategic regulatory advisory services to small‑ and m​id‑size growing biotech companies across a range of therapy areas and regions. Supporting meetings with regulatory agencies in Europe and North America. We also provide advice on organisational development and outsourcing key regulatory activities. It is never too soon to consider regulatory aspects of your development programme, and our approach is aimed at providing you with a flexible and targeted approach to maximise the probability of success.​​​​We are also based at the BioHub, Alderley Park, near Manchester.

Hilton Cambridge City Centre 20 Downing Street, Cambridge CB2 3DT, UK Tel: 01223 464 491 Email: stnhc‑salesadm@hilton.com Website: www.cambridge.hilton.com Contact: Amy Parnell

Located in the heart of the city, within walking distance to attractions and nightlife, Hilton Cambridge City Centre is the perfect base for exploring the university town. We’re easily accessible by road and rail, and just 45 minutes from London Kings Cross. As the largest central hotel in Cambridge, you’ll find all you need for an unforgettable stay including a new LivingWell Gym and Executive Lounge as well as a relaxed restaurant and lounge. Plan an event for up to 200 guests in our self‑contained meeting space, with six flexible meeting rooms and a stylish atrium with skylight.

Hologic Limited Heron House, Oaks Business Park, Crewe Road, Wythenshawe, Manchester M23 9HZ, UK Tel: 0161 946 2200 Fax: 0161 946 2211 Email: pharma@hologic.com Website: www.tepnelpharmaservices.com Contact: Dr Paul Docherty

Hologic is a leading global healthcare and diagnostics company with more than 5500 employees and offices in 15 countries. Through Tepnel, Hologic’s contract research business, we have been providing a full range of biomarker, companion diagnostics (CDx) and cGMP analytical services to the biopharma industry for more than 30 years. From our European HQ in Manchester, our portfolio includes DNA/ RNA extraction, sequencing, biomarker discovery, assay development and validation and CDx development in support of preclinical, clinical and personalised medicine studies. Our Livingston facility supports drug development with a range of services including stability and batch release testing.

Horton International Global Healthcare Belmont House, 13 Upper High Street, Thame, Oxon OX9 3ER, UK Tel: 020 7630 0200 Email: edwards@hortoninternational.com Website: www.hiexecutivesearch.com Contact: Paul Edwards

Horton International Global Healthcare is an executive search consultancy specialising in the recruitment of senior talent in the pharmaceuticals, life sciences and healthcare sector. We count amongst our clients four of the top 10 global pharmaceutical companies, as well as many other businesses in the biotech and medtech sector, and a portfolio of not‑for‑profit organisations, including government agencies and charities. We recruit senior managers across all functions, including R&D, clinical, regulatory, commercial and operations.

Hyper Recruitment Solutions (HRS) Amshold House, Goldings Hill, Loughton, Essex IG10 2RW, UK Tel: 020 3225 5120 Email: info@hyperec.com Website: www.hyperec.com Contact: Ricky Martin

108 | One Nucleus Directory 2017

Hyper Recruitment Solutions (HRS) is a specialist and highly compliant recruitment consultancy dedicated to the science and technology sectors. HRS, founded and run by Ricky Martin and in partnership with Lord Alan Sugar, has a wealth of recruitment expertise as well as compliance and commercial awareness. We offer a range of permanent, temporary and contract staff covering technical and commercial disciplines across the globe. Our vision is to provide recruitment solutions that will assist in the improvement and quality of life for all. HRS is a business made up of scientists supporting science.


Silver Members I

IDACO Consulting Limited 7 Parsonage Road, Chalfont St. Giles, Buckinghamshire HP8 4JW, UK Tel: 07795 397 349 Email: iancox@idacoconsulting.com Website: www.idacoconsulting.com Contact: Ian Cox

IDACO Consulting offers: strategic pharmaceutical and preclinical consulting services; due diligence; evaluation and de‑risking of R&D; business development support, scouting an extensive, purpose‑built academic network to identify new collaboration and in‑licensing opportunities for pharmaceutical, medical device and associated organisations; business development support for organisations wanting to access outsourcing and commercial networks; oversight and project management of outsourced CMC and preclinical projects; attending partnering conferences and exhibitions on behalf of clients; and identifying in‑licensing and out‑licensing opportunities and new partners and service providers.

Ideagen Ideagen PLC, Ergo House, Mere Way, Ruddington Fields Business Park, Nottingham NG11 6JS, UK Tel: 01629 699 100 Website: www.ideagen.com Contact: Alex McCormick

Q‑Pulse is a quality and safety management solution which, along with our validation services, supports life science organisations to continuously stand up to regulatory scrutiny which accelerates the time to market for products and services. Our solutions encourage adoption of a risk‑based approach to quality, safety and compliance management, which gives your business the confidence that your products and services are safe and fit for purpose.

Illingworth Research Limited Suite 5, Silk House, Park Green, Macclesfield, Cheshire SK11 7QJ, UK Tel: 01625 617 447 Email: info@illingworthresearch.com Website: www.illingworthresearch.com Contact: John Illingworth

Illingworth Research is a full service clinical CRO with experience across all phases of development from phase 1/proof of concept studies to post‑marketing studies. Illingworth has a network of clinical infrastructure covering most therapeutic areas, varying from clinical research units, primary, secondary and tertiary care sites across Europe, and with partners in North America and Australasia. Illingworth also provides research nurses to provide homecare visits to support clinical studies to optimise patient retention and compliance, as well as medical photography services.

Imanova Ltd Burlington Danes Building, Imperial College London, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK Tel: 020 8008 6000 Email: enquiries@imanova.co.uk Website: www.imanova.co.uk Contact: Dr Kevin Cox

Imanova has world‑leading expertise in imaging sciences and their application to the understanding of disease and translational drug development. An innovative joint venture, Imanova’s shareholders are the UK’s Medical Research Council and three world‑class London universities: Imperial College London, King’s College London and University College London. Imanova is a company with a depth of understanding in drug development and extensive experience using imaging to facilitate the development pipeline. Our academic expertise and extensive links with clinicians and scientists in our shareholder institutions provide unrivalled capabilities to facilitate drug development.

Immodulon Therapeutics 6‑9 The Square, Stockley Park, Uxbridge UB11 1FW, UK Tel: 020 3137 6346 Fax: 020 8929 9283 Email: info@immodulon.com Website: www.immodulon.com Contact: Ilda Guimarey

Immodulon Therapeutics is a leading biopharmaceutical company with one of the longest running research projects into how to harness the power of the immune system in treating cancer. Founded in 2007, Immodulon aims to bring to market an affordable immunotherapy treatment to transform the way that cancer is treated in the world today. Immodulon’s current focus lies predominantly in the treatment of melanoma and pancreatic cancer. Its flagship product IMM‑101 is an immune‑modulator and a naturally derived medical treatment that helps the immune system recognise and control cancer, working alongside other treatments without adding to toxicity levels.

www.onenucleus.com | 109


Silver Members I

Imperial College London ThinkSpace Block C, Centre House, 56 Wood Lane, London W12 7SB, UK Tel: 020 7594 5155 Email: thinkspace@imperial.ac.uk

Imperial College London ThinkSpace provides office and laboratory space for businesses to turn world‑leading research into new products and services. Imperial College London’s White City Campus will enable the co‑location of research and business on a scale that is unprecedented in London. This new innovation district will reinforce London’s status as a catalyst for scientific development and economic growth. Our flagship building, The Translation & Innovation Hub (I‑HUB) holds over 185,000ft2 of laboratory and office space in central London, available to lease to companies at every stage of their growth.

Imperial Consultants 3rd Floor, 58 Prince’s Gate, Exhibition Road, London SW7 2PG, UK Tel: 020 7594 6565 Fax: 020 7594 6570 Email: consultants@imperial.ac.uk Website: www.imperial‑consultants.co.uk Contact: Lynda Stamford

With access to over 4000 research‑active academics and Imperial College London’s state of the art facilities, Imperial Consultants (ICON) has been helping organisations, large and small, find solutions to their business needs for over 25 years. As the wholly owned consultancy company of Imperial College London, Imperial Consultants was formed to harness the breadth and depth of expertise at the College and deliver cutting‑edge solutions for industry, government and the third sector. Each year, our professional team supports around 500 clients on 600 projects, with 40 per cent delivered outside the UK in over 70 countries – creating impact beyond academia.

Imperial Innovations 52 Princes Gate, Exhibition Road, South Kensington, London SW7 2PG, UK Tel: 020 7581 4949 Website: www.imperialinnovations.co.uk Contact: Sarah Martin

Imperial Innovations creates, builds and invests in pioneering technologies addressing global problems in healthcare, energy, engineering and the environment. The company builds and invests in technology and healthcare opportunities based on intellectual property developed at, or associated with, the UK’s four leading research intensive universities: Cambridge, Oxford, UCL and Imperial College London. In addition, Imperial Innovations supports scientist‑entrepreneurs in the commercialisation of their ideas by leading the formation of new companies, providing facilities in the early stages, providing investment, leading and encouraging co‑investment to accelerate development, providing operational expertise and recruiting high calibre management teams.

IN‑PART Innovation Centre, 217 Portobello, Sheffield S1 4DP, UK Tel: 020 3286 5945 Email: robin@in‑part.co.uk Website: www.in‑part.co.uk Contact: Robin Knight

IN‑PART is a global university‑industry collaboration platform showcasing the latest opportunities from universities actively seeking to work with businesses. When the worlds of science and business meet, an intermediary is needed to ensure a technology’s successful commercialisation. Scientists need business professionals to guide their research for translation and businesses need to know what new technologies are available to benefit their sector. This is where IN‑PART comes in; it forms a conduit that links universities with decision makers in industry to facilitate the commercialisation of groundbreaking ideas and technologies.

INC Research (UK) Ltd Riverview, The Meadows Business Park, Station Approach, Blackwater, Surrey GU17 9AB, UK Tel: 01276 481 000 Fax: 01276 481 295 Email: info@incresearch.com Website: www.incresearch.com

110 | One Nucleus Directory 2017

INC Research is an organisation of therapeutically‑focused high performance teams, led by world‑class managers and leaders dedicated to helping our customers to bring products to market, to improve the health of people around the world. The Global Regulatory Consulting Group covers all regulatory aspects of every stage of your product’s life cycle, including pharmaceutical (CMC/quality) consulting, non‑clinical (pharmacology/toxicology) consulting, clinical pharmacology consulting and therapeutic/biostatistical consulting. In addition, we support pre‑approval and post‑approval regulatory operations. We have a global reach. We have proven experience with both large, medium and SME/start‑up pharma/ biopharma companies.


Silver Members I

Inngenii Limited 133 Station Road, Sidcup DA15 7AA, UK Tel: 07789 985 591 Email: keith@inngenii.com Website: www.inngenii.com Contact: K. Rodgers

Innovative, inspirational and ingenious solutions, inspiring and transforming businesses by enhancing value. Developing people, processes and organisations. Vision, strategy, leadership, executive inspiration, innovation, change, new product development, grants, funding, marketing and business development.

Innomech Ltd The Innovation Centre, Witchford, Ely, Cambs CB6 2HZ, UK Tel: 01353 667 394 Email: info@innomech.co.uk Website: www.innomech.co.uk Contact: Tim Mead

If you need to boost your manufacturing efficiency or move from a labour intensive prototype process to pilot or full scale, we would be happy to discuss your project. We offer initial advice and feasibility studies through to building production‑scale systems and are skilled in identifying and managing risk. Our experience comes from automating some of the most precise, delicate, complex and labour‑intensive processes around. Where regulatory compliance demands a detailed validation document package, we can assist with specifications test protocols. We have tried to add case studies to our website, but please ask about our experience in your industry.

Insights in Life Sciences Ltd (ilS) 50, Liverpool Street, London EC2M 7PR, UK Tel: 020 3713 7497 Email: ils@ilsintelligence.com Website: www.ilsintelligence.com Contact: Dr Pepi Hurtado / Dr Itziar Escudero

Insights in Life Sciences (ilS) is a global life sciences consultancy firm, specialised in all existing primary research solutions (ilS SolutionsSM). It provides life sciences companies with unique access to a broad range of life sciences experts recruited by pre‑defined knowledge and compliance criteria. Through ilS Primary Research Solutions (including in‑depth phone interviews, online surveys and expert onsite panels) companies can access remarkable insights directly from the world’s top experts. Leveraging on these insights, ilS allows life sciences companies to create and execute optimal pricing and market access strategies, and thus achieve a competitive advantage.

Instinctif Partners (Life Sciences) 65 Gresham Street, London EC2V 7NQ, UK Tel: 020 7457 2020 Fax: 020 7866 7900 Email: daniel.gooch@instinctif.com Website: http://lifesciences.instinctif.com Contact: Daniel Gooch

Instinctif Partners is an international business communications consultancy. The life sciences practice focuses on enhancing the value proposition for companies seeking investment, partnerships or customers. We work with clients to communicate the value of their science and innovation to stakeholders through the most relevant channels. We offer specialist expertise across corporate, financial, healthcare and marketing communications, covering all communications disciplines including strategic counsel, PR, IR, media relations, public affairs, crisis communications, internal communications, marketing, advertising, copywriting, design and event management. Our practice serves clients around the world from our headquarters in London, and bases across Europe, Asia‑Pacific and the USA.

Tel: 01353 653 855 Website: www.nexus-ie.co.uk

Nexus Intelligent Engineering, Cambridge UK is a speciality contract manufacturing engineering partner providing build, assembly and maintenance services worldwide for complex technical products and devices to a range of industries, including medtech, pharma, oil and gas, and food. 1920-Nexus_advert_AC.indd 1

27/01/2017 13:14

www.onenucleus.com | 111


Silver Members I

Institute of Biotechnology Master’s in Bioscience Enterprise Programme, Chem Eng & Biotech, University of Cambridge, Philippa Fawcett Drive, Cambridge, Cambridgeshire CB3 0AS, UK Tel: 01223 334 168 Fax: 01223 334 162 Email: lma31@cam.ac.uk Website: www.ceb.cam.ac.uk/mbe Contact: Dr Linda Allan

The Master’s in Bioscience Enterprise (MBE) programme is a postgraduate business course intended for those who have the ambition to take up leadership, executive or consultancy roles in the life science sector, or to follow an entrepreneurial career. Students are based in purpose built facilities, where lectures and case studies are frequently delivered by senior company executives, clinicians and academic entrepreneurs, a combination that provides an unparalleled educational experience. Previous experience in business, medicine or academia is helpful but not essential. Bursaries covering a portion of the tuition costs are available for selected applicants.

Institute of Food Research Norwich Research Park, Colney Lane, Norwich, Norfolk NR4 7UA, UK Tel: 01603 255 000 Fax: 01603 507 723 Email: ifr.communications@ifr.ac.uk Website: www.ifr.ac.uk Contact: Christian Roghi

The Institute of Food Research (IFR) addresses relationships between food and health, food and the gut, food safety and food chain sustainability. On April 28 2017 IFR will transform into the Quadram Institute, a pioneering facility for food and health research, developing solutions to challenges in food‑related disease and health. Combining academic excellence with clinical research in a state‑of‑the‑art building, QI researchers will work interdisciplinarily on food innovation, the gut and microbiome, healthy ageing and food safety. Strong links with pharmaceutical and food industries will translate QI science into new foods and therapies, delivering benefits for society and the bioeconomy.

Integrated Medicines Ltd Topfield House, Ermine Street, Caxton, Cambridge CB23 3PQ, UK Tel: 01954 718 122 Email: info@integratedmedicines.co.uk Website: www.integratedmedicines.co.uk Contact: Eddie Blair

Integrated Medicines Ltd (IML) has taken its experience of working with industry stakeholders, notably establishing the economic value of relationships between pharmaceutical and diagnostic companies, to develop care pathway simulations that articulate economic, clinical and resource benefits to additional stakeholders, such as regulators, payers, clinicians and patients. As an exemplification of this approach, IML developed baseline care pathways for bacterial sepsis through examination of patient records and discussions with NHS Trust clinicians, hospital biochemists and diagnostic test providers, and then superimposed on this baseline a series of assumptions that generated an alternate simulated pathway aided by innovation.

InterFocus Ltd Pentagon Business Park, Cambridge Road, Linton CB21 4NN, UK Tel: 01223 894 833 Fax: 01223 894 235 Email: sales@interfocus.co.uk Website: www.mynewlab.com

InterFocus is a Cambridge‑based manufacturer and installer of laboratory furniture and associated services. Our turnkey service provides a complete, bespoke laboratory design and build solution, including M&E and building works.

Invest Newcastle NewcastleGateshead Initiative, 9th Floor, Baltic Place East, South Shore Road, Gateshead NE8 3AE, UK Tel: 0191 440 5764 Email: invest@ngi.org.uk Website: www.investnewcastle.com Contact: Matt Bratton

112 | One Nucleus Directory 2017

Life sciences is a growing key sector in Newcastle, and Invest Newcastle provides a range of services to potential and existing investors. Our service is bespoke and will be led by client needs, but could include: research, intelligence and statistics to support business case development; recruitment and retention guidance; property solutions (office, labs, industrial, etc.); advice on local finance, grants and incentives; marketing and PR support; access to world‑leading centres of excellence, clusters and universities.


Silver Members J

IP Pragmatics Limited 160 Fleet Street, London EC4A 2DQ, UK Tel: 020 3176 0580 Email: info@ip‑pragmatics.com Website: www.ip‑pragmatics.com

IP Pragmatics works with growing biotech companies and universities to create and realise value from their life science intellectual property, through provision of cost‑effective and commercially relevant patenting, licensing and business development services. We help our clients to identify, manage and create value from a broad range of intellectual property (IP) assets.

Ipsen Development Ltd 190 Bath Road, Slough SL1 3XE, UK Tel: 01753 627 700 Email: keith.foster@ipsen.com Website: www.ipsen.com Contact: Keith Foster

Ipsen is a global specialty‑driven pharmaceutical group with total sales exceeding €1.4 billion in 2015. Ipsen sells more than 20 drugs in more than 115 countries, with a direct commercial presence in more than 30 countries. Ipsen’s ambition is to become a leader in specialty healthcare solutions for targeted debilitating diseases. Its fields of expertise cover oncology, neurosciences and endocrinology. Ipsen’s commitment to oncology is exemplified through its growing portfolio of key therapies improving the care of patients suffering from prostate cancer, bladder cancer and neuro‑endocrine tumours. Ipsen also has a significant presence in primary care.

Ithaka Life Sciences Ltd St John’s Innovation Centre, Cowley Road, Cambridge CB4 0WS, UK Tel: 01223 703 146 Email: info@ithaka.co.uk Website: www.ithaka.co.uk Contact: Paul Rodgers

Ithaka is a provider of venture management services for the life sciences sector. The company’s team of industry experts works closely with companies ranging from SMEs to multinationals, universities and research organisations, investors, government agencies, the NHS and other public sector bodies to support them in the commercialisation of life science technologies. With its unique network of contacts, flexibility to work on projects of all sizes, breadth and depth of experience across the life science sector and a proven track record in achieving client satisfaction, there are many reasons for choosing to work with Ithaka.

J A Kemp 14 South Square, Gray’s Inn, London WC1R 5JJ, UK Tel: 020 3077 8600 Email: mail@jakemp.com Website: www.jakemp.com

J A Kemp is one of the largest UK and European patent and trademark attorney firms, with over 70 science and technology graduates including more than 20 biotechnology and life sciences specialists, many with PhDs. J A Kemp is renowned for its experience of prosecuting patent and trademark applications worldwide and its success in oppositions and appeals. The firm conducts intellectual property litigation in the UK and European courts. With offices in London, Oxford, Cambridge and Munich, the firm’s clients range from small companies to multinational corporations and some of the most prestigious universities in the world.

JLC Biopharma Consulting 84 Lausanne Road, London N8 0HP, UK Tel: 07739 743 192 Email: jenny@jlcbiopharma.co.uk Contact: Jenny Craigen, PhD

We provide consultancy and contracting services for discovery and early development of biopharma products, specialising in haematology, immuno‑oncology and immuno‑inflammation. Jenny Craigen, Founding Director, has a successful track record in leadership of therapeutic antibody projects from initiation to FTIM (including ADCs, Fc enhancement, effector function), and design and management of IND enabling pharmacology studies and translational strategies. Services can be ‘hands on’ or advisory and include: scientific evaluation of preclinical and translational packages; project planning; technical advice for immunology; writing position pieces; data integrity advice/technical report writing; outsourcing pharmacology studies; managing collaborations.

www.onenucleus.com | 113


Silver Members J

Juneberry Limited 112 Canterbury Street, Cambridge CB43QE, UK Tel: 01223 514 229 Email: karen.hills@juneberry.net Website: www.juneberry.net Contact: Dr Karen Hills

Providing marketing and business development services on a contract/consultancy basis to the biotech/healthcare sector. Dr Karen Hills is a ‘sole trader’ based in Cambridge with a background in genomics, who has spent the last 20 years or so working in companies ranging from early stage start‑ups to Big Pharma. Her experience includes both business development (mostly small biotech/pharma) and marketing (small biotech and multi‑million pound speciality brands for Bristol Myers‑Squibb). Karen’s focus is on providing ad hoc/project-based resources to support existing business development/marketing professionals in the Cambridge area. Her most recent work was for 14M Genomics.

Kathryn Simpson Consulting Ltd United Kingdom Tel: 07599 822 396 Email: kathryn@kathrynsimpson.com Website: www.kathrynsimpson.com Contact: Kathryn Simpson

Kathryn Simpson Consulting started in 2007 to lead people, teams and organisations to strong and energetic futures. It specialises in strategic change consulting to knowledge‑based (e.g. pharma, consumer, life sciences) organisations in the UK, Europe and Canada. Services include facilitating and developing strategic plans, scoping strategic initiatives, and coaching leaders to create and achieve their shared vision through flawless execution. As a result, businesses have seen their ideas turn into action plans, have enhanced their capabilities to set and achieve goals, and developed behaviours that have driven measurable and sustained success.

kdm communications ltd Suite 3, Cressner House, 12 Huntingdon Street, St Neots PE19 1BG, UK Fax: 01480 477 833 Email: ideas@kdm‑communications.com Website: www.kdm‑communications.com Contact: Annabel Sedgwick

kdm communications is a full service business‑to‑business marketing agency with international reach, specialising in life science, technical and medical marketing. Established in 1984, kdm communications offers its clients a trusted blend of scientific understanding and marketing expertise. We can work with our clients at both a strategic and tactical level, and pride ourselves on bringing a wealth of experience, relevant knowledge, creative flair and the odd bit of constructive criticism to the table.

Kinesis Ltd 9 Orion Court, Ambuscade Road, Colmworth Business Park, St Neots, Cambridgeshire PE19 8YX, UK Tel: 01480 212 122 Email: sales@kinesis.co.uk Website: www.kinesis.co.uk Contact: Angelica Chhiba

Kinesis is an award‑winning leading international supplier and servicer of chromatography, liquid handling, sample storage and medicinal chemistry consumables and equipment. The company’s products are used extensively in the pharmaceutical, environmental, forensic, life sciences, food, biotechnology and academic markets. Kinesis was established in 1997 in the UK. Today, the company has expanded its reach globally with subsidiary offices in Australia, Germany, Italy and the USA. A network of international distributors ensures the Kinesis range of products is available worldwide.

King’s College London King’s Commercialisation Institute, 16th Floor, Tower Wing, Guy’s Hospital, Great Maze Pond, London SE1 9RT, UK Tel: 020 7188 6665 Fax: 020 7188 8330 Email: commercialisation@kcl.ac.uk Website: www.kcl.ac.uk/commercialisation Contact: Michael Garrison

114 | One Nucleus Directory 2017

Established in 2012, the King’s Commercialisation Institute challenges the traditional commercial transaction approaches pursued by typical university technology transfer offices. The Institute is staffed by experienced life science industry professionals who understand the requirements for development and commercialisation of new technologies. The focus is to engage actively with King’s research projects to achieve commercial translation that is better aligned with the needs of the industry and which captures the potential benefits that new technology can deliver. The Institute accelerates the commercial translation of disruptive life science technologies for the benefit of society and our industrial and investor partners.


Silver Members L

KISS Communications Unit B, The Cube Building, 17‑21 Wenlock Road, London N1 7GT, UK Tel: 020 8123 4575 Email: simon@kisscom.co.uk Website: www.kisscom.co.uk Contact: Simon Fryer

KISS is the creative agency that clarifies the complex. We create ideas that will surprise you, worry the competition and add value to your business. Our proven ability to cut through complexity and deliver stand out creative and campaigns based on a single minded proposition has enabled us to win a fantastic family of innovative clients in the science, technology and healthcare sectors. Based in Cambridge, London and Oxford, KISS provides strategy-led marketing services including advertising, branding, digital, design, public relations, animation, video, CRM, corporate communications, reporting, exhibition and social media.

KWS BioTest Ltd 47‑48 Martingale Way, Portishead, Bristol BS20 7AW, UK Tel: 01275 460 903 Email: info@kwsbiotest.com Website: www.kwsbiotest.com

KWS BioTest is an established contract research organisation providing a wide range of drug discovery services spanning preclinical development from early cell biology, through efficacy models to clinical sample analysis. KWS provides clients with a powerful combination of world‑leading scientific expertise coupled with the latest methods and technologies to ensure the highest levels of quality and service at all times. We specialise in the areas of immunology, inflammation and infection and work closely with our clients in the testing of their novel small molecules, biologics and ADCs as treatments for human disease, including specific experience across global vaccine development initiatives.

LA Design Product Design and Development, 105 High Street, Berkhamsted, Hertfordshire HP4 2DG, UK Tel: 01442 862 631 Fax: 01442 874 354 Email: info@la‑design.co.uk Website: www.la‑design.co.uk Contact: Matthew Brown

New clients come to LA for many reasons, but it’s our business focused approach and award‑winning innovative solutions that result in unprecedented customer retention and highly effective long‑term working collaborations. LA is one of the UK’s most respected and successful industrial design and product development consultancies. Having won 10 DBA Design Effectiveness Awards, we continue to develop our services in line with rapidly changing requirements and deliver profitable brand‑led solutions that connect technology and business with people. A winning combination.

La Playa Limited Merlin Place, Milton Road, Cambridge, Cambridgeshire CB4 0DP, UK Tel: 01223 200 664 Email: hanna.beaumont@laplayainsurance.com Website: www.laplayainsurance.com Contact: Hanna Beaumont

La Playa offers 10 per cent discount to One Nucleus members on new insurance policies. An independent specialist broker based in the UK and USA, La Playa supports organisations in life sciences, ICT, electronics, cleantech, nanotechnology and mediatech with comprehensive insurance and expert professional advice. We understand your work and we speak your language – our intelligent approach combines tailored insurance solutions with sound risk management to secure highly competitive rates. We also provide a range of independent financial advice, from business protection to employee benefits. Contact us today for your free insurance ‘health check’ – you’ll enjoy working with us!

Labmode Ltd 409 Centennial Avenue, Elstree, Borehamwood WD6 3TN, UK Website: www.labmode.co.uk

www.onenucleus.com | 115


Silver Members L

Laboratory Solutions Recruitment Warners Farm, Main Road, Howe Street, Chelmsford, Essex CM3 1BL, UK Email: matthew@lab‑sol.co.uk Website: http://lab‑sol.co.uk

Laboratory Solutions is an experienced and successful recruitment company with a reputation based on repeat business, referrals and recommendations. We pride ourselves on our friendly, professional approach to make the recruitment process more pleasurable. We want you to succeed so let us take the stress out of your recruitment process or next career step and do all the hard work for you. Our experienced consultants take the time to listen to gain a good understanding and we specialise in scientific, clinical, sales and engineering recruitment. If we can help, please drop Lab Solutions a line.

Labstract Ltd c/o Nuformix, Edinburgh House, St John’s Innovation Centre, Cowley Road, Cambridge CB4 0DS, UK Tel: 01223 423 667 Email: info@labstract.co.uk Website: www.labstract.co.uk

Labstract is a bioscience support company providing support services to biotechs, pharma and entrepreneurs across the region. Labstract offers advice and support to start‑ups setting up new lab facilities and provides a dry powder sample management and shipping service from its laboratories in Cambridge to virtual and part‑virtual companies without in‑house facilities of their own.

LifeSciences British Columbia Suite 580 ‑ 1285 West Broadway, Vancouver, BC V6H 3X8, Canada Tel: +1 604 669 9909 Fax: +1 604 669 9912 Email: info@lifesciencesbc.ca Website: www.lifesciencesbc.ca Contact: Elizabeth Sun

LifeSciences BC is a not‑for‑profit, non‑government industry association that supports and represents the life sciences community of British Columbia through leadership, facilitation of investment and partnering, and advocacy and promotion of our world‑class science and industry. Life sciences sectors, from biopharmaceuticals and medical technology to digital health and medical devices, are integrated into our organisation and our activities, ensuring that no life sciences sector is working in isolation and that all sectors come together in a comprehensive, complementary and coordinated fashion. Throughout the year, LifeSciences BC undertakes numerous programmes and projects in support of these sectors.

Liftstream Ltd 67 Grosvenor Street, London W1K 3JN, UK Tel: 020 3178 5864 Email: info@liftstream.com Website: www.liftstream.com Contact: Karl Simpson

Liftstream provides executive recruitment services exclusively to the life sciences sector. Liftstream works with clients in the UK and internationally to fulfil strategic hiring requirements at board and C‑level, as well as across all key functions of R&D and commercial. Liftstream’s flexible partnership approach provides clients with experienced executives aligned to your business goals and company culture. Founded in 2003, Liftstream has recruited for sector‑leading biotechnology, pharmaceutical and medical technology companies, as well as many start‑ups. Our focus is on delivering what your company requires, combining our sector knowledge, process and networks to deliver key leaders.

Linguamatics 324 Cambridge Science Park, Milton Road, Cambridge CB4 0WG, UK Tel: 01223 651 910 Fax: 01223 654 869 Email: enquiries@linguamatics.com Website: www.linguamatics.com Contact: Phil Hastings

116 | One Nucleus Directory 2017

Linguamatics is the world leader in deploying innovative natural language processing (NLP) based text mining for high value knowledge discovery and decision support. Linguamatics I2E is used by the FDA, leading academic and healthcare institutions and 17 of the top 20 pharmaceuticals for extracting information from unstructured and semi‑structured content. I2E can be used to mine a wide variety of text resources, such as scientific literature, patents, electronic health records, clinical trials data, news feeds and proprietary content. It is available as an in‑house enterprise system, a managed service and software‑as‑a‑service (SaaS) on the cloud.


Silver Members M

Link China Pharma Solutions Ltd Milton Hall, Ely Road, Milton, Cambridge, Cambridgeshire CB24 6WZ, UK Tel: 01223 828 215 Email: mma@chinapharma.co.uk Website: www.chinapharma.co.uk Contact: Marshall Ma

Link China Pharma Solutions is a UK, Cambridge‑based dedicated technology brokerage and services provider, bringing in‑depth China industry experience and market knowledge to provide a range of specialist services to promote research co‑operation, technology transfer and business collaboration between China and UK/ EU life science research institutes, biotech and pharmaceutical companies, maximising the value of research and business alliances. LCPS is currently advising Europe‑based biotech companies for strategic partnership deals with China biopharmaceutical companies. LCPS successfully negotiated many deals, including the Mucosis and BCHT investment license deal, ImmBio‑LIBP licensed co‑development deal on TB vaccine and Sareum‑HMU licensed co‑development Aurora/FLT3 deal.

Liquidity Services UK Ltd Suite 107 1st Floor, 1 Alie Street, London E1 8DE, UK Tel: 020 7098 3792 Email: help@go‑dove.com Website: www.go‑dove.com Contact: Graeme Fraser

GoIndustry DoveBid (Go‑Dove), a Liquidity Services marketplace, provides professional buyers with access to an unparalleled variety and volume of surplus business assets from Liquidity Services’ 8000‑plus clients, which include Fortune 1000 and Global 500 organisations, as well as government agencies. Go‑Dove offers buyers excellent deals on surplus assets in over 500 categories, with thousands of items auctioned off every week. Major asset categories we sell: biotech, life sciences and pharmaceutical; food and beverage; consumer goods; transportation/fleet services; commercial printing; electronic manufacturing; automotive, aerospace and industrial manufacturing; IT and network computing; metalworking and machine tools.

LucyJRobertshaw 3 Hillcrest Avenue, Heaton Mersey, Stockport SK4 3JS, UK Tel: +46 70 628 0230 Email: lucyrobertshaw@live.co.uk Website: www.lucyjrobertshaw.com Contact: Lucy Robertshaw

LucyJRobertshaw was established in March 2012 in Sweden to provide consultancy services to companies within the Anglo Nordic life science sector, with a base in the Stockholm region covering the Swedish and UK markets. We have many years’ experience within the pharmaceutical sector, bringing a wealth of knowledge and expertise to our clients who are looking to develop their business. LucyJRobertshaw understands the challenges within the life science sector, bringing a new outlook to business development. We offer our clients a planning strategy for their journey in sales, and help with assisting in marketing their services and products.

M‑Files Davidson House, Forberry Square, Reading RG1 3EU, UK Tel: 0330 088 9569 Website: www.m‑files.com Contact: Rob Swan

M‑Files is an enterprise information management company providing document (DMS) and quality management software (QMS) systems. We recently launched an out‑of‑the‑box QMS for small to medium life science companies providing licence, configuration, training and support, yet are flexible to support the nature of early stage companies. Automated processes including SOP management and training, CAPA and risk management, regulatory document control, HR processes and workflow are all included.

Managing Resources Ltd 18 Topcliffe Way, Cambridge CB1 8SH, UK Tel: 01223 566 158 Email: info@managingresources.com Website: www.managingresources.com

Many of our present and future clients are based in countries like the USA, Canada, Australia and New Zealand. They recognise the European potential for their products; they require our help in understanding the market opportunity, appreciating the varied healthcare structures in different countries, including regulatory affairs, determining the best entry strategy and finding the right partners, possibly including M&A. Also, we assist companies with the development of their staff by delivering programmes designed with One Nucleus and similar organisations. Programmes addressing strategic issues in the sector have been offered in conjunction with several business schools.

www.onenucleus.com | 117


Silver Members M

Mandeville Technology Limited 26 Borough Lane, Saffron Walden CB11 4AG, UK Tel: 07989 420 696 Email: andrew_muncey@hotmail.com Contact: Andrew Muncey

Mandeville Technology Limited provides flexible chief financial officer or finance director services to healthcare and technology companies. Services in the following areas are available: accounting, including audit preparation, financial reporting and management accounts; company secretarial; corporate finance, including deal structuring, disposals, equity funding, financial modelling, mergers and acquisitions, valuations and venture debt; corporate and financial strategy, including budgeting and forecasting, business and financial advice and corporate restructuring; employee incentive schemes, including EMI share options, employee benefit trusts and share purchase schemes; non‑executive director; and taxation, including EIS, R&D tax credits and VAT.

MAP BioPharma Limited Upper Pendrill Court, Ermine Street North, Papworth Everard CB23 3UY, UK Tel: 01480 832 360 Email: enquiries@mapbiopharma.com Website: www.mapbiopharma.com Contact: Jasmine Groves

MAP offers an up to date, validated, web-based subscription service that acts as a ‘virtual’ expert to help you achieve pricing and reimbursement across the EU. If what you need is not already there, we will complete the additional work, usually at no extra charge. To supplement this, we offer product specific, one to one expert strategic advice on a consulting basis throughout the product life cycle. MAP BioPharma was set up to deliver simple, clear process maps, guides and ‘holding your hand’ consulting support to the global life sciences industries – including: biotech, pharmaceutical, medical device, diagnostics and vaccines.

Markel UK Limited Verity House, 6 Canal Wharf, Leeds LS11 5AS, UK Tel: 0845 351 2600 Email: marketinguk@markeluk.com Website: www.markelinternational.com/lifesciences Contact: Simon Webster

Specialist insurance for your sector. Our specialist biomedical and life sciences insurance policy provides tailored protection for businesses across the pharmaceutical, biotechnology, medical device, dietary supplement, medical food, laboratory instruments and equipment industries. From start‑up through research and development and clinical trials, to product manufacture and worldwide sales, we offer comprehensive coverage, providing for the commercial insurance needs of UK‑based SMEs. Markel is a worldwide insurance brand with generations of experience in niche markets. Ask your insurance broker for a Markel quote to gain access to our products and expertise or visit our website for further information on www.markelinternational.com/uk.

Marks & Clerk 62‑68 Hills Road, Cambridge CB2 1LA, UK Tel: 01223 345 520 Fax: 01223 365 560 Email: sportman@marks‑clerk.com Website: www.marks‑clerk.com Contact: Simon Portman

Marks & Clerk is a renowned intellectual property firm. With a unique combination of patent attorneys, trademark attorneys and IP lawyers, we are able to offer advice on all aspects of IP protection, including prosecution, portfolio strategy, litigation, due diligence, licensing and other commercial contracts, along with IP valuation through our consulting practice. Renowned for our client‑led approach, we are a top tier firm, noted by Managing Intellectual Property in its IP Stars guide for our life sciences practitioners. With eight UK and eight overseas offices, we work with national and international clients across the life sciences spectrum, from start‑ups to multinationals to academic institutions.

Mathys & Squire LLP The Shard, 32 London Bridge Street, London SE1 9SG, UK Tel: 020 7830 0000 Fax: 020 7830 0001 Email: cetitmus@mathys‑squire.com Website: www.mathys‑squire.com Contact: Craig Titmus

118 | One Nucleus Directory 2017

Mathys & Squire has over 100 years of experience in providing intellectual property services to UK industry, and is recognised as a tier 1 patent firm by the Legal 500. Our attorneys work across a number of technical disciplines, including biotechnology, pharmacology, healthcare and medical devices and chemistry. We have a global track record in securing valuable intellectual property rights for universities, government, start‑ups and spin‑out companies. Our attorneys also specialise in freedom to operate and due diligence activities, and we are particularly proud of our extremely high success rate in both defending and challenging patents before the European Patent Office.


13 July 2017 Cambridge, UK

Translating UK scientific excellence into global therapeutic strategies

ON Helix is the established translational research conference brought to you by One Nucleus, which brings academia and industry together under one roof; bridging the gap between basic research and launching a product onto the market. Our Keynote Addresses:

• • •

Sharon Vosmek, CEO, Astia David Tapolczay, CEO, MRC Technology Sara-Jane Dunn, Microsoft

What to expect from the conference:

• • • • •

ON Helix Welcome Reception and BioNewsRound Award | 12 July 2017 Interactive Panel Debates 300 + Delegates 30 Exhibitiors 1-2-1 Partnering

Wellcome Genome Campus Conference Centre, Cambridge onhelix.com | join in the conversation #onhelix17


Silver Members M

Maypond Ltd Old Farm, Croydon, Lower Road, Royston SG8 0HE, UK Email: angus.hone@maypond.co.uk Website: https://uk.linkedin.com/in/angus-hone-b17a4710 Contact: Angus Hone

Highly commercial CFO/COO of healthcare, medical diagnostics and software technology.

Mercury Bioscience Consultants Ltd London, UK Email: bdh@domayne‑hayman.com Contact: Dr Barbara Domayne‑Hayman

Mercury Bioscience Consultants Ltd brings corporate strategy and business development expertise, based on personal track record of initiating and negotiating major deals. Considerable direct experience of fundraising, from venture capital, business angels and non‑dilutive sources, including USA government funding, Innovate UK (previously Technology Strategy Board), etc. Hands‑on experience as a biotech CEO underpins real understanding of what it takes to build a successful early stage biotech business in terms of the four key pillars: technical (including IP aspects); financial; commercial/market; and human resources/team.

Metrion Biosciences 3 Riverside, Granta Park, Cambridge, Cambridgeshire CB21 6AD, UK Tel: 01223 919 100 Email: info@metrionbiosciences.com Website: www.metrionbiosciences.com Contact: Marc Rogers

Metrion Biosciences is a fully independent CRO providing access to a range of high quality ion channel screening assays to the pharma, biotech and spin‑out sectors on a fee‑for‑service or collaboration basis. Metrion Biosciences’ specialist ion channel expertise includes a comprehensive panel of in vitro cardiac ion channel safety assays including hERG, translational native cell and phenotypic assays for neurological and cardiotoxicity testing, and a range of ion channel drug discovery services such as cell line development and optimisation. Our staff have discovery, preclinical and clinical development expertise in therapeutic areas including neuroscience, pain, cardiovascular, autoimmune and metabolic disease.

Mewburn Ellis LLP Newnham House, Cambridge Business Park, Cambridge CB4 0WZ, UK Tel: 01223 420 383 Fax: 01223 423 792 Email: mail@mewburn.com Website: www.mewburn.com Contact: Dr Nick Sutcliffe

Mewburn Ellis LLP is one of the UK’s largest firms of European patent, trademark and design attorneys. We have a large and highly respected team of life sciences specialists who are regarded for their superior knowledge and expertise in this often contentious area of patent law. Our attorneys are drawn from a broad range of technical backgrounds, enabling us to bring experience appropriate to our clients’ technology in each case we handle. We are top tier listed in the Legal 500 and have been singled out in particular for our expertise in life sciences.

Mills and Reeve LLP Botanic House, 100 Hills Road, Cambridge CB2 1PH, UK Website: www.mills‑reeve.com Contact: Kevin Calder

120 | One Nucleus Directory 2017

Mills & Reeve is one of the UK’s leading healthcare law firms and advises government, health and academic institutions on IP and related issues, such as licensing, MTAs, supply of human tissue, stem cells, clinical trials and medical devices. We have extensive experience in the EU, USA, China and other countries, which allows us to help you achieve your global aspirations. Our life sciences group is a full service practice, with top ranking lawyers in corporate finance and funding, we can support you from seed to listing and beyond. Our clients include biotech companies, investors, NHS organisations and world‑class universities.


Silver Members M

Milvus Healthcare Consulting Ltd 5 Dean Grove, Wokingham RG40 1WD, UK Email: gdacoppen‑email@yahoo.com Website: https://uk.linkedin.com/in/dcoppen Contact: Donald Coppen, PhD, MBA

Provision of interim management and consulting services in business development and alliance management to pharma/biotech/medtech companies.

Mission Therapeutics Ltd Moneta Building, Babraham Research Campus, Cambridge CB22 3AT, UK Tel: 01223 497 454 Email: info@missiontherapeutics.com Website: www.missiontherapeutics.com Contact: Paul Wallace

Mission Therapeutics is a private drug discovery and development company focused on selectively targeting deubiquitylating (DUB) enzymes to treat cancers, neurodegenerative and other diseases. Mission has established a broadly‑applicable DUB inhibitor platform that enables the pursuit of multiple DUB inhibitor programmes. It has raised a total of $125 million from investors – such as Imperial Innovations Businesses LLP, Sofinnova Partners, SR One, Roche Venture Fund, Pfizer Venture Investments and Woodford Patient Capital Trust Plc – and is based at the Babraham Research Campus.

Money Mover Milton Hall, Ely Road, Milton, Cambridge CB24 6WZ, UK Tel: 01223 928 030 Email: partnerships@moneymover.com Website: www.moneymover.com Contact: Amanda Nunn

Money Mover is an online foreign exchange and global payments platform specifically designed for small and medium‑sized enterprises (SMEs). It immediately cuts the costs of making currency payments and inter‑account transfers by up to 90 per cent, in comparison with bank transfers. The service is transparent, low‑cost and simple to use, with a web interface and functionality which have been developed to meet the requirements of SMEs, such as payment tracking, live quotes and complete cost transparency. There is no commitment, no minimum term and no membership fee.

MRC Centre c/o MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK Tel: 01223 267 000 Email: techtran@mrc‑centre.cam.ac.uk Website: www.mrc.ac.uk

The MRC’s mission is to improve human health through world‑class medical research. Its major investments in Cambridge are through the MRC Laboratory of Molecular Biology and in research units working in the fields of cancer, obesity and diabetes, nutrition, mitochondrial biology, cognition and brain sciences and in biostatistics. In addition, the MRC funds further research and training in universities in this region via grants, specialist MRC centres, and support for individual fellowships and studentship programmes. This MRC funding exceeds £120 million per annum. Training, translation, exploitation and knowledge transfer are key priorities for the MRC.

MRC Technology 7th Floor, Lynton House, 7‑12 Tavistock Square, London WC1H 9LT, UK Tel: 020 7391 2700 Email: info@tech.mrc.ac.uk Website: www.mrctechnology.org

MRC Technology is an independent life science medical research charity committed to drastically improving positive patient outcomes everywhere. As a champion for human health, MRC Technology partners with academic, biotechnology, pharmaceutical, and charity organisations to move promising medical research forward into viable and accessible patient treatments. Our people combine commercialisation and technology transfer/IP management skills with diagnostic and drug discovery expertise, specialising in small molecule and therapeutic antibodies. MRC Technology projects have led to the approved drugs Tysabri®, Actemra®, Entyvio® and Keytruda®, changing the lives of countless patients by harnessing the potential of science.

www.onenucleus.com | 121


Silver Members M

MS Therapeutics Limited Beechey House, 87 Church Street, Crowthorne RG45 7AW, UK Email: info@mstherapeutics.com Website: www.mstherapeutics.com

MS Therapeutics Ltd applies its core skills in IP generation, product development and preclinical proof of concept validation to develop medicines specifically in the field of autoimmune and inflammatory disease, including multiple sclerosis (MS) and related orphan or rare diseases. The company primarily generates innovations and improvements relating to known compounds and pathways for which regulatory and technical risks are reduced.

Murray International Partners United Kingdom Tel: 07557 805 935 Email: michael.murray@murrayinternationalpartners.com Contact: Dr Michael Murray

Murray International Partners carries out deal management services: building and executing deals in intellectual asset‑rich industries in the life sciences and technology sectors. We integrate assessments of technology and accessible markets and product specification, to determine product marketing position, commercial strategy, IP strategy and valuation, before leading/supporting business development and deal negotiations. Our clients are international and include: small to medium cap companies, start‑ups, research organisations, universities and investors. We work closely with law, patent and accountancy practices, often being referred to their clients to assist with commercial and IP strategy.

NanoTemper Technologies Ltd Sheraton House, Castle Park, Cambridge CB3 0AX, UK Tel: 01223 370 033 Email: info@nanotemper.co.uk Website: www.nanotemper.co.uk Contact: Dr James Wilkinson

Our unique portfolio of patented technologies simplifies, accelerates and improves research quality in a variety of lab settings. At NanoTemper Technologies, we are passionate about achieving excellence in everything we do. This has made us the partner of choice for thousands of researchers worldwide in pharmaceutical and biotechnology industries, as well as in academic settings. Our collaborative approach, science-driven insights, high-quality proprietary instruments and analytical technologies focus on helping researchers make the greatest impact – with maximum speed, efficiency and precision. A dedicated team of experts operates globally to offer you and your team individual application support and to ensure maximum instrument capability.

NC3Rs (National Centre for the Replacement, Refinement and Reduction of Animals in Research) Gibbs Building, 215 Euston Road, London NW1 2BE, UK Website: www.nc3rs.org.uk

The National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3Rs) is an independent scientific organisation. We offer new collaborative and funding opportunities linking large industry, SMEs and academics to drive innovation and technological developments that improve the predictivity of non‑clinical safety and efficacy testing, replace or reduce the need for animals in research and testing and lead to improvements in welfare where animals continue to be used.

New England Biolabs (UK) Ltd 75/77 Knowl Piece, Wilbury Way, Hitchin, Hertfordshire SG4 0TY, UK Tel: 01462 420 616 Fax: 01462 421 057 Email: info.uk@neb.com Website: www.neb.uk.com

122 | One Nucleus Directory 2017

NEB UK supplies both NEB Inc and Cell Signaling Technology Inc (CST) products. These include a broad range of reagents and kits for basic and applied research at the DNA, RNA and protein levels. These products are also for use in drug development and screening, as well as for use in platform technologies and as raw materials in kit manufacture. We supply standard catalogue products as well as custom and bulk formulations. We would like to partner with you from R&D downstream to market. Call us to discuss your ‘biological component’ needs. For unsurpassed scientific excellence, choose NEB UK.


Silver Members O

Novasecta Ltd 137 Euston Road, London NW1 2AA, UK Tel: 020 3384 3850 Website: www.novasecta.com Contact: John Rountree

Novasecta is a specialist management consulting firm for pharma/biotech companies. Novasecta’s clients are primarily CEOs, commercial heads and R&D heads. We provide them with practical solutions based on a profound understanding of their unique businesses and their industry context. We deliver the strategic counsel, insight and change that they need to drive performance improvement and sustainable growth.

Odgers Berndtson 20 Cannon Street, London EC4M 6XD, UK Tel: 020 7529 3071 Email: melanie.west@odgersberndtson.com Website: www.odgersberndtson.co.uk Contact: Dr Melanie West

Odgers Berndtson is a leading executive global executive search firm, with exceptional reach across the private and public sectors. It is the only international search firm with offices throughout the UK as well as over 51 international offices in 27 countries. The company is privately owned and has been operating for over 40 years in the UK. The Life Sciences Executive Search Practice at Odgers Berndtson works with pharmaceutical, biotechnology, medical devices and diagnostics organisations across the public and private sector from early stage start‑ups to FTSE and NASDAQ 100 global leaders.

Olswang 90 High Holborn, London WC1V 6XX, UK Tel: 020 7067 3400 Email: millie.williams@olswang.com Website: www.olswang.com Contact: Millie Williams

Our life sciences group is unique amongst UK and European firms, incorporating a full service patent prosecution and attorney practice alongside lawyers from other complementary service lines. We provide a one‑stop‑shop for life science companies including IP (prosecution and litigation), corporate, tax (including patent box), commercial and regulatory expertise, plus expertise in reputation management, social media, employment and data protection. We currently work with a range of life science clients, from individual inventors through to mid‑sized biotechnology companies and multinational pharmaceutical companies, and are experienced in tailoring the services we provide on a client by client basis.

OncoLytika Ltd 1 The Firs, Wilburton, Ely, Cambridgeshire CB6 3FL, UK Tel: 07812 046 749 Email: info@oncolytika.com Website: www.oncolytika.com Contact: Dr Mark Eccleston

OncoLytika is an innovative technology development company with internal programmes ranging from veterinary medicine to drug delivery and medical imaging. These programmes are funded via OncoLytika’s scientific and management consultancy services. We support preclinical drug development and diagnostic programmes as well as drug delivery and imaging projects. We specialise in product diversification through innovation and partnering. We are leveraging our business planning, grant writing and R&D experience with our network of contacts across a diverse range of industrial, charitable and academic organisations to accelerate our development programmes and those of our partners.

Open Audience Ltd 52 Billet Lane, Berkhamsted HP4 1DR, UK Tel: 01442 461 575 Email: info@openaudience.co.uk Website: www.openaudience.co.uk Contact: Leslie Robertson

We love an audience! Connecting with and inspiring audiences with events, workshops, virtual events and webinars – all brilliantly designed, developed and delivered. Helping you collaborate with delegates in more engaging ways, leading to behavioural changes, more memorable interactions, and better quality, measurable outcomes. Bringing you events on five continents, in person and virtually. Reaching out to engage audiences in creative and memorable ways. Working with a spectrum of clients, from rapidly growing agencies to the largest global organisations in healthcare, financial services and retail. We have a deep understanding of audiences and how to make them feel valued and vital.

www.onenucleus.com | 123


Silver Members O

Organisation Effectiveness Cambridge (OE Cam LLP) 3 Wellington Court, Cambridge CB1 1HZ, UK Tel: 01223 269 009 Email: info@oecam.com Website: www.oecam.com Contact: Gary Ashton

OE Cam is a specialist firm of business psychologists and consultants who maximise the effectiveness of individuals, teams and organisations. We do this by building the capability of an organisation to deliver its strategy. We help develop their leaders, design efficient structures, align individual behaviours and engage employees in the change. Our services include talent management (executive assessment, leadership development, executive coaching, performance management) and organisation development (board development, organisation design, culture audit and development). Clients include: AB Agri, Abcam, Babraham Bioscience, The Body Shop, CSR, Daiichi Sankyo, the Department of Health, GEO, Greene King, Odeon, Primark, Ridgeons, TWI and the University of Cambridge.

Osborne Clarke One London Wall, London EC2Y 5EB, UK Tel: 020 7105 7296 Email: janita.good@osborneclarke.com Website: www.osborneclarke.com Contact: Dr Janita Good

As a leading international law firm, we provide business‑focused solutions to meet our clients’ advisory, litigation and transactional needs. Our advice is framed by our deep knowledge of our clients’ industries and our international reach; we have a presence across Europe and in the USA. Our life sciences and healthcare team advises the full range of organisations across the sector, from health tech innovators to global pharmaceutical companies. We are recognised for our strength in mid‑market transactions and intellectual property, and many of our specialists have advanced scientific qualifications, ensuring we deliver commercially relevant solutions to our clients.

Owlstone Medical Ltd 127 Cambridge Science Park, Milton Road, Cambridge CB4 0GD, UK Tel: 01223 428 200 Fax: 01223 428 201 Website: www.owlstonemedical.com

Owlstone Medical has developed a breathalyser for disease. Focusing on non‑invasive diagnostics for cancer, infectious and inflammatory diseases, our aim is to save 100,000 lives and $1.5 billion in healthcare costs by 2020. Our FAIMS (field asymmetric ion mobility spectrometer) platform is programmable in software to detect targeted disease biomarkers in breath (and other clinical samples). FAIMS is sensitive enough to allow early diagnosis of many medical conditions. We are developing tests for lung and colorectal cancer, two of the most common cancer killers. We also sell R&D tools and services to academic, clinical and pharma partners to develop FAIMS diagnostics for their own applications.

Oxford BioTherapeutics Ltd 94A Milton Park, Abingdon, Oxon OX14 4RY, UK Tel: 01235 861 770 Fax: 01235 861 771 Email: admin@oxfordbiotherapeutics.com Website: www.oxfordbiotherapeutics.com Contact: Emily Goodey

At Oxford BioTherapeutics we are developing revolutionary antibody‑drug conjugates for cancer. These have the potential to enhance treatment effectiveness while sparing healthy tissue and reducing side effects. Unlocking the power of these treatments requires precision. Precision targeting, precision delivery and precision cancer eradication. Our mission is simple: to transform patients’ lives with precision cancer therapy.

P.A.S.M. Limited 19 Florence Road, Sanderstead CR2 0PQ, UK Tel: 020 8645 0599 Email: peterm@pasmonline.com Website: www.pasmonline.com Contact: Peter Motteram

124 | One Nucleus Directory 2017

PASM provides specialist services to support projects from transition out of preclinical into clinical, through the development programme and on to submission. Combining expertise in project management and GCP, PASM brings together teams of functional experts to plan and support your path to market. Much of our work involves helping companies with CRO selection and oversight. We stay with you to support the project quality, the budget and timeline reporting, and help you gain access to your project. From offices in Boston and London, we also provide individual services such as QA GCP audit or operational and commercial project review.


Silver Members P

Page White and Farrer Bedford House, John Street, London WC1N 2BF, UK Tel: 020 7831 7929 Fax: 020 7831 8040 Email: email@pagewhite.com Website: www.pagewhite.co.uk Contact: Jeff Daniels

Established in 1875, Page White and Farrer is a leading UK firm of patent and trademark attorneys. Our comprehensive services include assistance with invention capturing, filing and obtaining patents in the UK, at the European Patent Office and worldwide. We conduct European patent oppositions, advise on freedom to operate, and provide due diligence and portfolio services. We have a wealth of experience working with individual inventors, academic/research institutions, start‑ups and other emerging entities. Our specialist team of life science attorneys are experts in providing legal, practical and strategic advice, translating your innovation into valuable business assets.

Paul Hastings (Europe) LLP Ten Bishops Square, 8th Floor, London E1 6EG, UK Tel: 020 3023 5100 Fax: 020 3023 5109 Email: coreyblake@paulhastings.com Website: www.paulhastings.com Contact: Corey Blake

Our life sciences practice is highly regarded and has been recognised as Life Sciences Group of the Year by Law360 and Pharmaceutical Team of the Year by Intellectual Property Magazine. We pride ourselves on our creativity and strategic understanding of corporate transactions in this sector. Our depth of knowledge and experience with business transactions in the life sciences industry allows us to work effectively on a wide variety of transactional matters, including: initial public offerings; mergers, acquisitions, and disposals; R&D and commercial collaboration agreements; technology transfers and licensing; clinical trial agreements; debt financings; joint ventures; supply agreements and manufacturing agreements.

PCI Clinical Services Wye Valley Business Park, Hay-on-Wye HR3 5PG, UK Email: sales@pciservices.com Website: www.pciservices.com

PCI Pharma Services is an integrated full service provider, a proven and trusted partner to leading companies in the global healthcare industry. We offer unparalleled expertise and experience in taking compounds from the earliest stages of development through to successful commercialisation, delivering speed‑to‑market and commercial success for our customers. Our core services support each stage of the product life cycle, including drug development, clinical trial supply, commercial launch and ongoing commercial supply. We partner with clients in providing innovative technologies, flexible solutions, and an integrated supply network supporting lifesaving medicines destined to over 100 countries around the world.

Peptinnovate Ltd Stevenage Bioscience Catalyst, Gunnels Wood Road, Stevenage, Hertfordshire SG1 2FX, UK Email: apl@peptinnovate.com Website: www.peptinnovate.com Contact: Andrew Lightfoot

Peptinnovate is a clinical stage biopharmaceutical company discovering and developing new treatments for inflammatory disease. Peptinnovate is founded on the principle that mycobacterium tuberculosis (mTB) can modify the human immune system through co‑evolution with man. mTB, over 40,000 years, developed mechanisms in which the allergic and asthma phenotypes in man can be reduced. Peptinnovate has identified molecules derived from mTB that appear to have the same desired immuno‑modulating effects in preclinical models and has optimised proprietary drug candidates. Backed by an expert team, Peptinnovate is focused on developing a range of therapies for debilitating respiratory and immuno‑inflammatory diseases.

Pharma International Innovation Centre, Gewerbestrasse 14, CH‑4123 Allschwil, Baselland, Switzerland Tel: +41 61 483 0978 Fax: +41 61 483 0979 Email: alan.chalmers@datanetworks.ch Website: www.in‑allschwil.ch Contact: Alan Chalmers

Pharma International provides global pharmaceutical regulatory consultancy services with an emphasis on the emerging markets. Fully licenced by Swissmedic, Pharma International is authorised to trade in biotechnology, pharmaceuticals and medical devices internationally, as well as providing Swiss Qualified Person services. Seminars on regulatory affairs, especially Asia including ASEAN, China, Korea and India, are conducted regularly and can be adapted to in‑house requirements.

www.onenucleus.com | 125


Silver Members P

PharmaGuide Ltd 53A Canterbury Street, Cambridge CB4 3QG, UK Tel: 01223 556 966 Email: ed.zanders@pharmaguide.co.uk Website: www.pharmaguide.co.uk Contact: Dr Edward Zanders

PharmaGuide Ltd provides training, coaching and consultancy in biopharmaceutical research and development. Courses include ‘How the Drug Discovery Industry Works’ and ‘Presentation Skills for Scientists’. Clients include business executives, technical translators and young scientists from academia and industry.

Pharmidex Pharmaceutical Services Ltd 3rd Floor, 14 Hanover Street, London W1S 1YH, UK Tel: 0870 240 5978 Fax: 0845 125 9586 Email: bd@pharmidex.com Website: www.pharmidex.com Contact: Martin Barrett

Founded in 2002, Pharmidex provides high quality experimental preclinical ADMET/PK data, critical to the progression of drug discovery programmes. Co‑located in London, Hatfield and Stevenage BioScience Catalyst, we have comprehensive in‑house laboratory facilities as well as extensive in vitro assay options. This enables us to set up bespoke tailored studies designed to meet experimental needs. Through extensive knowledge of drug discovery and development, Pharmidex has been able to deliver a high level of customer satisfaction and forge several strategic international alliances, focusing on the following: in vitro ADMET, in vivo pharmacology, CNS, oncology, toxicology, bioanalysis/metabolite identification and zebra fish.

PHG Foundation 2 Worts Causeway, Cambridge CB1 8RN, UK Tel: 01223 761 900 Email: info@phgfoundation.org Website: www.phgfoundation.org Contact: Dr Philippa Brice

The PHG Foundation is an independent health policy think‑tank; our mission is making science work for health. We evaluate and harness the potential of new bioscience and technologies to deliver better, more personalised healthcare, providing policy and decision‑makers with knowledge, tools and opportunities to support prompt clinical implementation of the best innovations to promote health, prevent and treat disease. Our work includes shaping the policy debate; debating the future of healthcare; providing the secretariat to the All‑Party Parliamentary Group on Personalised Medicine; collaborative projects with health professionals and other stakeholders; and provision of public and commercial sector consultancy services.

Phico Therapeutics Ltd Babraham Research Campus, Babraham, Cambridge CB22 3AT, UK Tel: 01223 496 755 Fax: 01223 496 018 Email: phico.admin@phicotx.co.uk Website: www.phicotx.co.uk

Phico Therapeutics is a UK‑based biotechnology company developing novel, antibacterial therapies for the treatment of serious hospital infections caused by Gram‑negative bacteria. Phico’s groundbreaking SASPject™ platform utilises programmable nano‑delivery vehicles to deliver a unique antibacterial protein, SASP, to target and inactivate bacterial DNA. SASPs bind to all bacterial DNA, irrespective of sequence, and are not impacted by spontaneous mutations in DNA, or the import of new DNA, key ways in which bacteria develop resistance to antibiotics. In this way Phico’s SASPject products have a clear advantage over current antibiotics, directly tackling the genetic cause of antibiotic resistance.

Phospho Biomedical Animation London, UK Email: info@phospho.co.uk Website: www.phospho.co.uk Contact: Dr Jeroen Claus

126 | One Nucleus Directory 2017

At Phospho we tell biomedical research stories visually, combining scientific accuracy with a cinematic touch to captivate both specialist and lay audiences. Any research, from medical imaging to the biochemistry of small molecule drugs, benefits from being communicated clearly. Animation is an excellent tool for this, using striking images to showcase science in the most compelling way. Get in touch and we’ll make your research beautiful.


Silver Members P

PiR Limited 14B Raleigh House, Compass Point Business Park, St Ives, Cambridgeshire PE27 5JL, UK Tel: 01480 499 580 Email: resourcing@pir‑resourcing.com Website: www.pir‑resourcing.com Contact: Sally Hope

PiR is a specialist recruitment company, established for over a decade, focused exclusively on identifying senior talent who deliver strategically and operationally, as well as adding value to international life sciences organisations. The relevance and depth of PiR’s expertise is reflected in the team’s combined life science recruitment experience of over 40 years; across key business functions at leadership and expert level. Our exclusive focus on, and network in, the sector ensures our solutions are aligned and relevant to client companies, reflecting our inherent understanding of the life science industry. PiR’s client services include: executive search, interim management services and talent mapping.

Potter Clarkson LLP The Belgrave Centre, Talbot Street, Nottingham, Nottinghamshire NG1 5GG, UK Tel: 01159 552 211 Fax: 01159 552 201 Email: info@potterclarkson.com Website: www.potterclarkson.com Contact: Richard Wells

At Potter Clarkson LLP we recognise the need to understand our clients’ technologies and business objectives in order to devise effective patent strategies. We have a team of over 35 in our biotechnology and chemistry group. Three quarters of the group hold a PhD in a relevant discipline. Many also have research experience in the pharmaceutical industry or academia. We also have patent groups specialising in other technology areas including nanotechnology, computing, electronics, telecommunications, medical engineering, materials science, software, mechanical engineering, textiles, trademarks, etc.

PPMLD Ltd 12 Micheldever Road, Lee, London SE12 8LX, UK Tel: 020 8852 2758 Email: info@ppmld.com Website: www.ppmld.com Contact: Dr Ralph White / John Faulkes

We believe people rise to the challenges of complex and difficult projects with limited resources when we tap into their natural desire to communicate and collaborate in finding solutions. If your middle/project managers operate with the right mix of strong and empowering leadership that will produce highly engaged, entrepreneurial teams, keen to over achieve. We help you transform the efficiency of any activities that involve collaborations – development projects, partnerships and alliances. We assess your operations quickly and recommend the highest impact, lowest cost options to make rapid change.

Premier Workplace Services Premier House, 1 Ardra Road, London N9 0BD, UK Tel: 020 8976 2100 Email: info@premierworkplaceservices.co.uk Website: www.premiermoves.net Contact: Pamela Chambers

Premier Workplace Services is a commercial relocations company that specialises in providing workplace services to the life science, healthcare and laboratory sectors. Our services include relocations, move management support, filing audit and inventory services, interior fit out, refurbishment and sustain and renew services. In addition, Premier have a fleet of air ride vehicles, including generator vehicles and ADR trained drivers to transport hazardous samples, chemicals, fridges and equipment. Premier also have an in house dangerous goods safety advisor to ensure that all consignments are handled and transported safely.

Prism Ideas Beam Heath Way, Nantwich CW5 6PQ, UK Tel: 01270 621 724 Website: www.prismideas.com

Prism Ideas is a drug development and medical affairs consultancy. We support both large and small pharma with scientific communications, internal briefing documents, clinical trial design and support, advisory boards and promotional compliance. Prism has an international client base with offices in the UK and Switzerland.

www.onenucleus.com | 127


Silver Members P

ProductLife Ltd The Jeffrey’s Building, St John’s Innovation Park, Cowley Road, Cambridge CB4 0DS, UK Tel: 01223 402 660 Fax: 01223 413 689 Email: tbrett@productlife‑group.com Website: www.productlife‑group.com Contact: Trevor Brett

ProductLife Ltd is UK-based, part of the Productlife Group (PLG). Providing consultancy and outsourced service solutions, including: regulatory affairs and CMC; clinical safety reporting, medical monitoring, pharmacovigilance (PV) and medical information; cosmetics and borderline; and life sciences consulting, e.g. regulatory information management. PLG becomes an immediate asset via a unique combination of strategic and operational experience and capabilities across the client product development continuum.

Propath UK Ltd Willow Court, Netherwood Road, Hereford HR2 6JU, UK Tel: 01432 354 052 Email: askpropath@propath.co.uk Website: www.propath.co.uk

Propath UK is a leader in the UK and Europe for GLP and GCP compliant histology and molecular pathology services to pharmaceutical and biotech industries, with a history spanning beyond 30 years. Our focus is on preclinical safety assessment and clinical trial support for biopharmaceuticals. Propath provides regulatory‑compliant services in therapeutic antibody tissue cross‑reactivity, immunohistochemistry, ISH, FISH, histopathology, digital image analysis and brightfield and fluorescence whole‑slide digital scanning. Our reputation has been gained by focusing relentlessly on the quality of our advice, the standard of our work and the responsiveness of our service.

ProPharma Partners Limited The Courtyard, 30 Worthing Road, Horsham RH12 1SL, UK Tel: 01403 793 769 Email: mail@propharmapartners.uk.com Website: www.propharmapartners.uk.com

Our partners all have extensive experience across large pharmaceutical and entrepreneurial biotechnology companies. We have offices in London, San Francisco and Tokyo, and we assist or have assisted clients as diverse as UCB, Toray, Zysis, Imperial Innovations, MMV, Cinven and Spinifex who have been bought by Novartis. Key areas we consult in include: medicinal chemistry/candidate selection; product development; non‑clinical, clinical and regulatory strategy development and implementation; global product and patent licensing; corporate partnering; merger and acquisition advice and due diligence; product development plans; assistance with VC and translational funding; intellectual property strategy and management; and business development strategy.

Protogenia Consulting Ltd PO Box 289, Ely CB7 9DR, UK Tel: 07905 321 515 Email: info@protogeniaconsulting.co.uk Website: www.protogeniaconsulting.co.uk

Protogenia Consulting Ltd offers preclinical and clinical development consultancy services for pharmaceutical and non‑pharmaceutical products. With over 25 years’ industry experience we offer strategic planning and programme management to enable early clinical development of small molecules, peptides, ATMPs and biologics; regulatory document writing (e.g. IMPD, IB, IND/CTA submission, MAA expert review); CRO selection, contract negotiation and study management/monitoring; programme management up to Ph2a; assistance in developing quality management systems (SOPs) and project management of grant funding submissions (e.g. MRC, Wellcome Trust). We also have a broad network of drug development contacts (e.g. CMC, regulatory affairs, QA and analytical services).

Public Health England Business Development, Porton Down, Salisbury, Wiltshire SP4 0JG, UK Tel: 01980 612 768 Fax: 01980 612 241 Email: business.development@phe.gov.uk Website: www.gov.uk/phe Contact: Christine Scott

128 | One Nucleus Directory 2017

We offer flexible and wide ranging scientific services to industry, governments and academia from across our network of specialist laboratories and two internationally recognised reference and research facilities at Colindale in north London and Porton Down in Wiltshire. This includes bespoke services for translational research, development and testing of novel antimicrobials, diagnostics, vaccines, therapeutics and other interventions against infectious diseases and across healthcare and public health. Allied with experience in emergency preparedness and planning, plus EQA schemes and four culture collections, PHE is one of the UK’s leading organisations dedicated to combating worldwide health threats and supporting international biomedical research.


Silver Members Q

QRC Consultants Ltd Silvaco Technology Centre, Compass Point, St Ives, Cambridgeshire PE27 5JL, UK Tel: 01480 309 349 Email: enquiries@qrcc.co.uk Website: www.qrcc.co.uk Contact: Sarah Fryer

QRC Consultants, experienced quality, regulatory and clinical professionals dedicated to providing high quality, cost‑effective solutions for biopharmaceutical companies in early clinical development. We offer technical expertise with strengths including: understanding regulatory environment governing clinical trials globally; regulatory agency meetings and submissions – trial management, and monitoring and audit of trials. Experience of small molecules, biological and advanced therapies. Services include: quality assurance – set-up and maintenance of QMS, GCP audits and agency inspection preparation; regulatory affairs, CTA submission, agency meetings, document writing, SME and EU legal representative services, and bespoke procedural and GCP training; plus clinical trial project management/monitoring.

Quality Care Cleaning Limited Copley Hill Business Park, Cambridge Road, Babraham, Cambridge CB22 3GN, UK Tel: 01223 833 300 Fax: 01223 837 362 Email: info@qualitycarecleaning.co.uk Website: www.qualitycarecleaning.co.uk Contact: Paul Heales

Quality Care Cleaning is a commercial cleaning contractor with over 35 years of experience in all aspects of workplace cleaning. Operating within a 30‑mile radius of Cambridge, Quality Care provides a range of cleaning services predominantly in the science sector, specialising in laboratory cleaning, office cleaning, carpet cleaning, window cleaning, builders’ cleans and other support services. We place great importance on providing a high quality and accountable service, striving to exceed the expectations of our customers. Accredited for safecontractor, ISO 9001 and National Federation of Master Cleaners, we offer our clients absolute peace of mind when operating on their sites.

Quebec Government Office 59 Pall Mall, London SW1Y 5JH, UK Tel: 020 7766 5900 Fax: 020 7930 7938 Email: qc.londres@mri.gouv.qc.ca Website: www.mri.gouv.qc.ca/en Contact: Patrick Philip

The Quebec Government Office in London was opened in 1962. It represents the Quebec government in the UK, Republic of Ireland and the Nordic Countries. Our mandate: increase the number of Quebec firms exporting to the UK, the Irish Republic and the Nordic countries, and the volume of exports; promote investment in Quebec among the seven countries in the territory covered; monitor trends in policy and commercial and technical practices in the target countries; and maintain ongoing links with firms from the territory that are currently established in Quebec.

Queen Mary Innovation Ltd Queen Mary University of London, Mile End Road, London E1 4NS, UK Website: www.qminnovation.co.uk

Queen Mary Innovation Ltd (QMI) is Queen Mary University of London’s (QMUL) wholly‑owned technology transfer company and is responsible for the commercialisation and management of the university’s intellectual property and portfolio of spin‑out companies. QMI protects and exploits QMUL’s research‑derived intellectual property and helps to maximise the economic and societal impact of that research.

Queen Mary University of London (Business Development) Mile End, London E1 4NS, UK Tel: 020 7882 5391 Email: c.lavery@qmul.ac.uk Website: www.qmul.ac.uk/business Contact: Cath Lavery

The Business Development Office provides access to Queen Mary University of London’s research capabilities and state‑of–the‑art facilities. Our team of business development managers can identify relevant academic expertise to meet your commercial requirements through collaborative research, contract research and consultancy.

www.onenucleus.com | 129


Silver Members Q

Quotient Clinical Ltd Mere Way, Ruddington, Nottingham NG11 6JS, UK Tel: 0115 974 9000 Email: info@quotientclinical.com Website: www.quotientclinical.com Contact: Robin Bodicoat

Quotient Clinical is a leading provider of early stage and specialist drug development services for pharmaceutical and biotechnology companies worldwide. Quotient Clinical brings innovation to drug development programmes by integrating formulation development, real‑time GMP manufacturing and clinical testing within one organisation. This integrated and unique platform is called Translational Pharmaceutics®. Translational Pharmaceutics significantly reduces the time and cost of bringing a drug to market. The company employs over 350 people, offering a full range of services from study set‑up right through to data analysis and reporting.

RadBee Ltd St John’s Innovation Centre, Cowley Road, Cambridge CB4 0WS, UK Fax: 01223 234 992 Website: www.radbee.com

Our founder, Rina Nir, launched RadBee with the goal of making quality assurance (QA) matter more. Coming from the medical devices industry, she saw how much time and effort is put into regulatory compliance, much of which doesn’t actually contribute to quality, excellence or better healthcare. Too often QA comes down to out‑of‑context formalities and chasing people around. Atlassian’s products can change all that. We combine our deep understanding of Atlassian’s powerful JIRA and confluence tools with understanding of the medtech, biotech and pharmaceutical industries. This enables us to implement transformative, easy to use and compliant quality management systems for our clients.

Rare Biotech Ltd London, UK Tel: 07827 323 421 Email: n.banister@rarebiotech.co.uk Website: www.rarebiotech.co.uk Contact: Dr Nigel Banister

Rare Biotech Ltd is a start‑up company based in London, UK that is targeting rare diseases and the development of orphan drugs. We aim to develop technologies with therapeutic and commercial potential, sourced from both academia and industry. We are seeking to translate a small portfolio of candidate therapies from proof of concept to phase 1/2 clinical trial. We operate as a ‘virtual company’ with the outsourcing of R&D to maximise the impact of funding. We are currently assembling the initial technologies and funding.

RD Connect Ltd 17 Mascotte Rd, Putney, London SW15 1NN, UK Tel: 020 8785 7198 / 07876 775 215 Email: cjh@rdconnect.net Website: www.rdconnect.net Contact: Caroline Hardwicke

RD Connect provides independent clinical research consultancy to the pharma/ biotech/diagnostics industry. Its principal, Caroline Hardwicke, believes that there is always a solution to a challenge in trial set‑up or execution. With industry experience of more than 25 years in all aspects of drug development from phase 1 to registration, she focuses on finding bespoke and personalised approaches (medical writing, clinical operations, study resourcing) to ensure client needs and the goals of the clinical trials are met.

Reddie & Grose LLP Clarendon House, Clarendon Road, Cambridge CB2 8FH, UK Tel: 01223 360 350 Fax: 01223 360 280 Email: enquiries@reddie.co.uk Website: www.reddie.co.uk Contact: Dr Neil Thornton

130 | One Nucleus Directory 2017

Reddie & Grose LLP is a leading patent and trademark firm established in Cambridge for more than 20 years, with clients both local and international. Its Cambridge office offers expertise in patents in biotechnology, pharmaceuticals, chemicals, engineering, cleantech, instrumentation, medical devices, materials, and software inventions. The firm is ranked in the top tier of Intellectual Property: Patent & Trade Mark Attorneys by the Chambers UK directory of leading legal firms: ‘We find their technical and commercial knowledge coupled with their legal understanding incredibly effective. They are excellent – quick to react and they provide clear and prompt advice’.


Silver Members R

Redx Pharma BioHub (2nd Floor, Block 3), Mereside, Alderley Park, Cheshire SK10 4TG, UK Tel: 01625 238 974 Email: m.craighead@redxpharma.com Website: www.redxpharma.com/home.php Contact: Dr Mark Craighead

Redx Pharma Plc is one of the youngest and largest biotechs in the UK with over 150 scientific personnel engaged in the discovery and early development of small molecule therapeutics targeting unmet needs in oncology, infectious diseases and immunology. Redx is progressing a broad pipeline of differentiated programmes for early‑stage collaborations with international biopharmaceuticals partners. We have experience of working in a variety of collaborations with a range of partners. We also work closely with academia and other emerging biotech companies to provide expedited routes to commercialisation for innovative programs which require hands‑on practical chemistry and pharmacology resources to stringent industry standards.

Research Applications Limited (RAL) U209, Cannon Wharf, Pell Street, London SE8 5EN, UK Tel: 07808 006 760 Email: luke@researchapplications.co.uk Website: www.researchapplications.co.uk Contact: Luke Brewer

Research Applications Limited (RAL) is a specialist company offering regulatory application services to assist commercial organisations, academics and others to undertake research within the NHS and beyond. We offer a protocol design service including statistical advice and can provide radiation, pharmacy, and costing reviews. We will complete the required regulatory forms and attend the ethics committee meeting on your behalf. Using our extensive knowledge of research in the UK we can help you select the best sites for your study. RAL is a gateway to research within the NHS. Let us help you get your study up and running.

Research Quality Association Ltd (RQA) 3 Wherry Lane, Ipswich IP4 1LG, UK Tel: 01473 221 411 Fax: 01473 221 412 Website: www.therqa.com

The Research Quality Association (RQA) is a professional membership body dedicated to informing and advancing its members. We provide status and visibility for individuals engaged in the quality of research concerning pharmaceuticals, agrochemicals, chemicals and medical devices. Since our inception in 1977, the Association has increased and evolved to reflect regulatory changes, the growing impact of regulatory inspection, and the ever‑changing structure and needs of the industry. The RQA has around 2400 members located in over 50 countries and many contacts with other research quality societies, related professional bodies and regulatory agencies throughout the world. These contacts allow regular exchange of information.

Results Healthcare 27 Soho Square, London W1D 3AY, UK Tel: 020 7629 7575 Website: www.resultshealthcare.com Contact: Kevin Bottomley

Results Healthcare is a leading international corporate advisory firm focused on mid‑market transactions with public and private healthcare and life science companies. We are long‑term relationship focused and provide advice across a number of areas. The team combines a range of complementary skill sets and expertise gained in the life sciences and finance industries. Our worldwide network of local offices ensures local expertise and support when executing local and cross‑border transactions. We advise on M&A transactions (both sell‑ and buy‑side), public to private transactions, fund raising (including VC and PE), MBOs, and licensing (products, IP and research based assets).

RiverRhee Consulting 49 Meldreth Road, Shepreth, Royston, Herts SG8 6PS, UK Tel: 07876 130 817 Email: elisabeth@riverrhee.com Website: www.riverrhee.com Contact: Elisabeth Goodman

RiverRhee Consulting works with managers and their teams to make the most of their time and expertise, and so achieve greater productivity, quality and satisfaction in their work. We offer training, coaching and in‑house workshops to help you: enhance your management skills; build and develop your team; deliver consistent quality to your customers; simplify and streamline your processes and ensure that your business changes succeed. Our scheduled courses include Introduction to Management (3‑day), Project Management (1‑day), The First Steps in Selling (1‑day), Introduction to Lean and Six Sigma (1‑day), and Managing Change (1‑day).

www.onenucleus.com | 131


Silver Members R

Roslin Cell Sciences Ltd Babraham Research Campus, Meditrina Building, Babraham, Cambridge CB22 3AT, UK Tel: 01223 804 095 Email: aidan.courtney@censobio.com Website: www.roslincellsciences.com Contact: Aidan Courtney

Roslin Cell Sciences goal is to create ‘large’ panels of cell lines from groups of donors all suffering from the same disease so that we can help our clients understanding of how the efficacy of their drugs varies across the population as a whole. This way we make the most of our resources and have a real impact on how drug discovery is done in the future. More importantly, we will help ensure that drugs can be targeted to those patients for which they will work, which means better drugs, better treatments for patients and reduced healthcare costs. Not only is this what we do, it’s something worth doing.

S‑Tech Insurance Services Ltd 154‑156 Victoria Road, Cambridge CB4 3DZ, UK Tel: 01223 324 233 Email: davidl@s‑tech.co.uk Website: www.s‑tech.co.uk Contact: David Lowe

S‑Tech has supported life science and related businesses since 1982, arranging insurance cover against a wide range of asset, liability and financial risks. We work with you to fully understand your business risks and to achieve the widest possible insurance protection. We are proud to be independent insurance brokers holding chartered status. We have access to insurance markets in the UK, including Lloyds of London, and overseas. Our clients range from start‑ups to international organisations, both UK and abroad. One Nucleus members will benefit from discounts off standard policy premiums, please check the support supplier page on www.onenucleus.com for further details.

Sagittarius IP 3 The Mill, Copley Hill Business Park, Cambridge Road, Babraham, Cambridge CB22 3GN, UK Tel: 01223 833 933 Email: mail@sagittariusip.com Website: www.sagittariusip.com Contact: Mark Gibson

Sagittarius IP is a firm of chartered and European patent attorneys who specialise in chemical, pharmaceutical and biotechnology subject matter. We provide the following services: drafting, filing and prosecution of patent applications and representation before the UK and European patent offices, including oppositions and other contentious work; filing of international patent applications (PCT) and control of worldwide patent prosecution; advice on IP strategy; freedom to operate investigation; IP due diligence and IP education. Sagittarius IP was established in 2002 and opened a Cambridge office in 2009.

Sahlgrenska Science Park Medicinaregatan 8A, SE‑413 46 Göteborg, Sweden Tel: +46 70 396 9309 Email: ted.ternander@sahlgrenskasciencepark.se Website: www.sahlgrenskasciencepark.com Contact: Ted Ternander

A unique meeting point in Gothenburg, Sweden. Sahlgrenska Science Park assists entrepreneurs and innovators in creating the best possible start for their promising life science venture. The success factor is the way we tailor our support to your needs in terms of: business development, competences, networking, financing, internationalisation, creative environment, laboratory space. Our remit is to strengthen and develop an international and attractive centre in the field of life science.

Sanofi 1 Onslow Street, Guildford, Surrey GU1 4SY, UK Tel: 01483 505 515 Fax: 01483 535 432 Email: emilie.braun@sanofi.com Website: www.sanofi.com Contact: Emilie Braun

132 | One Nucleus Directory 2017

Sanofi is a global integrated healthcare leader focused on patients’ needs. A strategic priority for Sanofi is to sustain innovation in R&D. We will increase our annual global R&D investments to €6 billion by 2020, with an increased capacity for external innovation. Our research interests and investment focus fall into two categories: 1) where we would like to sustain our leadership – diabetes, cardiovascular diseases, genetic rare diseases and vaccines; 2) where we would like to build a competitive position – immunology, oncology and multiple sclerosis. We will also invest opportunistically in neurodegeneration and infectious diseases.


Silver Members S

Sardis Capital Ltd No. 1 Farrier’s Yard, 77 Fulham Palace Road, London W6 8JA, UK Website: www.sardiscapital.com

Sarnmere Biotech Resourcing 9 The Moraine, Whittlesford, Cambridge CB22 4AH, UK Website: www.sarnmerebiotechresourcing.com

Sarnmere Biotech Resourcing (SBR) is a company committed to supporting life science start‑ups and SMEs to pair and harmonise the recruitment experience for both employers and candidates. We seek to achieve this by connecting skilled candidates with innovative and pioneering companies in developing and complementing their scientific communities.

Saxby Life Science Consulting 29 Mill Lane, Fordham, Ely CB7 5NH, UK Tel: 07795 956 533 Email: simsax2@aol.com Contact: Simon Saxby

Over 30 years of experience in senior management/executive positions in the UK, USA and Asia. CEO roles in private and public companies; 23 years of board experience; fundraising in Europe, UK, USA and Asia; M&A activity; licensing – products and technologies; global sales and marketing, sales management; design, build and management of cGMP biologics facilities in England, USA and Asia. We advise on: business plan development and fundraising, strategies for growth, M&A activity, licensing, contracts, management, sales and marketing, operations, GMP/ regulatory for biologics manufacturing, design and build of facilities.

Sciad Communications Ltd 71‑75 Shelton Street, Covent Garden, London WC2H 9JQ, UK Tel: 020 7470 8801 Email: info@sciad.com Website: www.sciad.com Contact: Deborah Cockerill / Richard Anderson

SCIAD is a marketing and communications agency that works with businesses in science, tech, healthcare and biotech. By integrating brand, digital and PR into one seamless communications programme we will help you make a positive impact with your stakeholders, drive business development and build a strong reputation. We aim to increase the success of our clients, helping them to stay ahead of their competitors and become market leaders. We are committed to helping companies that use science and technology as the basis for world changing ideas.

SciTechStrategy 36 Rotherwood Road, London SW15 1JZ, UK Tel: 07930 337 385 Email: robert@scitechstrategy.com Website: www.scitechstrategy.com Contact: Robert Thong

Robert Thong is an independent consultant, speaker and author on Bioscience Business Strategy, Collaborations and Change. Over the past 25 years, he has helped over 100 bioscience and healthcare organisations across a dozen countries in Europe, North America and Asia. Robert is the author of ‘Biopharma R&D Partnerships: From David & Goliath to Networked R&D’ (2016), a major book on R&D collaborations between smaller bioscience SMEs and academia with large multinational pharmaceutical corporations, based upon the experiences of over 40 companies that the author has consulted with or interviewed.

www.onenucleus.com | 133


Silver Members S

Scot Lift Systems Ltd Innovation House, Innovation Way, Discovery Park, Sandwich, Kent CT13 9FF, UK Tel: 01304 268 010 Email: johnwalmsley@scotlift.co.uk Website: www.scotlift.co.uk Contact: John Walmsley

ScotLift are a one-stop-shop for everything to do with pharmaceutical asset management. Let us look at your assets and discuss the various options to either upgrade, sell, value or take control of your assets on a fixed contract. Our services include: equipment sourcing/equipment selling; valuations; online auctions (www.biopharm-auctions.com); online store (www.biopharm-auctions.com); worldwide shipping, both export and import; export packing; cataloguing; (15,000ft2); packing supplies at trade prices; project management and labour for lab relocations; and purchase of complete laboratories/land.

Scottish Development International 60 Gresham Street, London EC2V 7BB, UK Tel: 07717 547 775 Email: emily.lekkas@scotent.co.uk Website: www.sdi.co.uk Contact: Emily Lekkas

Scottish Development International is the economic development agency for Scotland. Scotland hosts one of the largest life science clusters in Europe with significant international presence in research, development and manufacturing. With a long and remarkable history of medical and scientific discovery stretching back 200 years, Scotland has always been at the forefront of medical innovation. SDI can help your business navigate this rich and diverse biocluster and provide you with a wide range of investor support services to ensure your success in Europe.

Selvita Ltd 20 Station Rd, Cambridge CB1 2JD, UK Tel: 01223 803 808 Email: selvita@selvita.com Website: www.selvita.com

Selvita is a drug discovery company engaged in the research and development of breakthrough therapies in the area of oncology, as well as provision of integrated drug discovery services. Selvita offers drug discovery support at every stage of the early discovery phase up to the preclinical research phase. The company provides in silico drug design, synthesis of target‑focused libraries, SAR and ADME‑driven lead optimisation and toxicity prediction, followed by complex preclinical in vitro development. The company offices are located in the greater Boston area, USA; San Francisco, USA; Cambridge, UK; and Krakow, Poland.

Sequani Ltd Bromyard Road, Ledbury, Herefordshire HR8 1LH, UK Tel: 01531 634 121 Email: business.development@sequani.com Website: www.sequani.com

With 96 per cent of draft reports delivered on or before time it is little surprise that Sequani are one of the ‘go to’ providers for non‑clinical toxicology services. Whether you are at the early development stage, looking to conduct a first in man or proof of concept programme, or just for comfort in the knowledge the work will happen to schedule, Sequani can help. Our experienced team has the knowledge and know‑how to design and conduct both straightforward and complex studies. We offer a broad range of development services and are widely recognised for our expertise in reproduction toxicology.

Seven Bridges Genomics UK Ltd 101 Euston Road, 8th floor, London NW1 2RA, UK Tel: 020 3761 3427 Email: info@sevenbridges.com Website: www.sevenbridges.com Contact: Dr Julia Fan Li

134 | One Nucleus Directory 2017

Seven Bridges is the biomedical data analysis company accelerating breakthroughs in genomics research for cancer, drug development and precision medicine. The scalable, cloud‑based Seven Bridges Platform empowers rapid, collaborative analysis of millions of genomes in concert with other forms of biomedical data. Thousands of researchers in government, biotech, pharmaceutical and academic labs use Seven Bridges, including three of the largest genomics projects in the world: US National Cancer Institute’s Cancer Genomics Cloud pilot, the Million Veteran Program, and Genomics England’s 100,000 Genomes Project.


Silver Members S

SGS M‑Scan Ltd 2‑3 Millars Business Centre, Fishponds Close, Wokingham, Berkshire RG41 2TZ, UK Tel: 0118 912 1190 Email: uk.biopharma@sgs.com Website: www.sgs.com/biopharma

SGS Life Science Services is a leading contract service organisation providing analytical development, biologics characterisation, biosafety, utilities qualification, and quality control testing. With the largest wholly‑owned network of 18 laboratories in 11 countries, services include: analytical chemistry, microbiology, stability studies, bioanalysis, extractables/leachables, virology, and protein analysis. Additionally, we offer phase 1‑4 clinical services.

Sigma‑Aldrich Fancy Road, Poole, Dorset BH12 4QH, UK Tel: 01747 833 000 Website: www.sigma‑aldrich.com

Sigma‑Aldrich is part of the life science business of Merck KGaA, Darmstadt, Germany, and has 19,000 employees and 72 manufacturing sites worldwide, with a portfolio of more than 300,000 products enabling scientific discovery. The company’s biochemical and organic chemical products and kits are used in scientific and genomic research, biotechnology, pharmaceutical development, the diagnosis of disease and as key components in pharmaceutical and other high technology manufacturing. Merck has customers in life science companies, university and government institutions, hospitals and in industry. More than one million scientists and technologists use its products.

Silicon Valley Bank Alphabeta, 14‑18 Finsbury Square, London EC2A 1BR, UK Tel: 020 7367 7800 Email: ukbankingenquiries@svb.com Website: www.svb.com/uk Contact: Nooman Haque

Silicon Valley Bank supports innovation in the technology and life science sectors. We work with companies from the earliest stages through to maturity, providing financial solutions, banking, networking and insights. We work across biotech, medtech and digital health and have an enviable track record in championing our clients. Our team of nearly 40 life science bankers has longstanding relationships with investors and an unrivalled view of the industry through our 2200 life science clients. And with offices in Israel and China as well as the UK and US, Silicon Valley Bank is well placed to help you succeed.

Simbec‑Orion Group Ltd 7 Bath Road, Slough, Berkshire SL1 3UA, UK Tel: 01753 578 080 Email: information@simbecorioncro.com Contact: Magdalena Sommenvik

Simbec‑Orion is a full‑service boutique CRO covering FIH phase 1 studies through to phase 4. We offer a broader range of in‑house services than most major CROs, with our own central laboratories, pharmacovigilance, data management, statistics and IMP management. We have gained a depth of knowledge in oncology, rare and orphan, respiratory, metabolic disorders, infectious diseases and vaccines. We think with the same focus as you. We find novel, clever solutions, to save money and time and add unexpected value to your business. We employ 250 people and have offices in the UK, Europe and USA.

Simon Bennett Associates Ltd 17 Great Barrington, Burford OX18 4US, UK Tel: 07768 014 597 Email: simon@simonbennettassociates.com Contact: Dr Simon Bennett

SBA Ltd provides business development, licensing and market research support to the life sciences industry. We work with a range of clients from start‑up biotech, genomics and medtech companies, to mid‑cap and large pharma, and investors. We cover all aspects of business development and licensing, due diligence and valuations; advise and mentor early‑stage companies on business strategy; provide interim management support; audit business development functions; and run a series of short training courses, not only in the UK, but also across Europe, Russia/ CIS, Asia and the USA. Simon Bennett is a registered Growth Coach, and advises and mentors early‑stage companies.

www.onenucleus.com | 135


Silver Members S

South East Health Technologies Alliance (SEHTA) Lancasters, West End Lane, Henfield, West Sussex BN5 9RB, UK Tel: 07905 201 857 Email: info@sehta.co.uk Website: www.sehta.co.uk Contact: Clare Ansett

SEHTA (South East Health Technologies Alliance) is a health technology networking and business support organisation. We work as an honest broker to understand and meet the needs of academia, business and care/clinicians (ABC). We provide one‑to‑one support through our specialist network of technical advisers and we support our network through our events, website and representation to national and local government bodies.

SPD Development Company Limited Clearblue Innovation Centre, Priory Business Park, Stannard Way, Bedford, Bedfordshire MK44 3UP, UK Tel: 01234 835 303 Email: marika.reay@spdspark.com Website: www.swissprecisiondiagnostics.com Contact: Dr Marika Reay

Swiss Precision Diagnostics GmbH (SPD) is a world leader in the research, design, production and supply of advanced consumer diagnostic products. SPD brands, such as Clearblue® and PERSONA®, are acclaimed for their pioneering innovation and are familiar in many countries, trusted for their accuracy and simplicity. SPD is committed to advancing personal health and well‑being, and delivering to meet the needs of its consumers through a continuing flow of new and inventive developments. SPD’s UK based research centre, SPD Development Company Ltd, is at the sharp edge of innovation, and is fully engaged in the development of reliable diagnostic products.

SRG Unit 11, Cambridge Science Park, Milton Road, Cambridge CB4 0FE, UK Tel: 01223 394 230 Fax: 01223 223 828 Email: info@srg.co.uk Website: www.srg.co.uk Contact: Philippa Clark

SRG is a market‑leading recruitment company specialising in the science, clinical and engineering sectors. We provide temporary, contract and permanent career opportunities of all levels for our candidates and a comprehensive range of recruitment services for our clients, which range from spin‑out biotech firms to global pharmaceutical companies. With many of our team having worked as scientists before, we share our candidates’ passion for the industry and understand the challenges they face. As part of our Career for Life initiative, we put candidates at the centre of everything we do by providing expert guidance and exciting opportunities.

St John’s Innovation Centre Ltd Cowley Road, Cambridge CB4 0WS, UK Tel: 01223 420 252 Email: marketing@stjohns.co.uk Website: www.stjohns.co.uk

St John’s Innovation Centre provides a dynamic and supportive incubation environment to accelerate the growth of early‑stage, knowledge‑based companies in the Cambridge region. It was the first innovation centre of its kind in Europe and has become widely known for its success as a business incubator since it was founded by St John’s College, Cambridge, in 1987. It aims to provide the best strategic business advice, flexible accommodation, training and introductions. It is a Business & Innovation Centre (BIC) accredited by the European Business Network, and is a new partner in the Enterprise Europe Network for the East of England.

STARLAB (UK) Ltd 5 Tanners Drive, Blakelands, Milton Keynes MK14 5BU, UK Tel: 01908 283 800 Fax: 01908 283 802 Email: infoline@starlab.co.uk Website: www.starlab.co.uk

136 | One Nucleus Directory 2017

STARLAB is a liquid handling specialist whose success is founded on the manufacture of high quality laboratory consumables including TipOne pipette tips and ErgoOne pipettes. Our UKAS‑accredited pipette calibration service can service and calibrate all brands and types of pipette. We offer a range of servicing levels, as well as custom servicing to your exact requirements, both in‑house and at customer sites. Our expertise in all areas of liquid handling allows customers to focus their efforts on their research with the peace of mind that the instruments and consumables they are using will perform to the highest standards.


Silver Members S

Stellar Learning Kelynack, Reading Road, Burghfield Common, Reading, Berkshire RG7 3BH, UK Tel: 0118 983 6339 Email: stella@stellarlearning.co.uk Website: www.stellarlearning.co.uk/cms Contact: Stella Collins / Beth Curl

How you tick, make it stick! Do you understand how information gets from your brain into someone else’s? When you do, it becomes much easier to communicate with them. Through our Skills2Grow programmes we inspire scientists to excel when they communicate, whether face to face, in writing (from emails to technical reports), presentations, pitches or when managing people. We share insights from neuroscience and psychology to give you tools, techniques and processes to make your messages ‘sticky’, improving communication, compliance, productivity and profitability. Our clients include blue chip multinationals and award-winning, innovative science and technology companies.

Stratagem IPM Ltd Meridian Court, Comberton Road, Toft, Cambridge CB23 2RY, UK Tel: 01223 550 740 Fax: 01223 550 748 Email: patricia.willett@stratagemipm.co.uk Website: www.stratagemipm.co.uk Contact: Tricia Willett

Stratagem Intellectual Property Management Ltd is a full‑service, Cambridge, UK, based, outsourced intellectual property organisation and management company with global reach. Stratagem IPM Ltd fills a developing need within industry for the provision of strategic advice and intellectual property management for life science, medtech, cleantech and high technology companies. Stratagem’s qualified patent and trademark attorneys use a commercial perspective and hands‑on management approach to enhance the value of IP assets.

Strem Chemicals UK Ltd Newton Hall, Town Street, Newton, Cambridge CB22 7ZE, UK Tel: 01223 873 028 Fax: 0845 643 7362 Email: enquiries@strem.co.uk Website: www.strem.co.uk Contact: Debora Bestetti

Strem Chemicals UK Ltd has had a presence in the UK and Ireland for over 25 years. We distribute a wide range of high purity chemicals and speciality materials. These include: 1) a range of metals, inorganics, organometallics and nanomaterials; 2) patent‑free and proprietary catalysts and ligands for organic synthesis, often at kilo‑scale, including many for asymmetric transformations. Our licensed technologies come royalty‑free for R&D purposes. Our clients include academic, industrial and governmental research laboratories, as well as commercial scale businesses in the pharmaceutical, microelectronic and chemical industries.

Susan R. Windham‑Bannister 19 Elizabeth Ridge Road, Carlisle 01741, USA Email: suewb51@gmail.com Contact: Dr Susan Windham-Bannister

Dr Susan Windham‑Bannister is a nationally and internationally recognised innovation expert. She was recognised by the Boston Globe as one of the ‘10 Most Influential Women in Biotech’ in 2013. Dr Windham‑Bannister currently serves as Managing Partner of Biomedical Innovation Advisors LLC – which she co‑founded with Dr Harvey Lodish of the Whitehead Institute, MIT – and also serves as the President and CEO of Biomedical Growth Strategies, LLC. Both of these advisory firms leverage Dr Windham‑Bannister’s experience as the immediate past President and CEO of the Massachusetts Life Sciences Center, administering the $1 billion Massachusetts Life Sciences fund.

Sygnature Discovery Ltd BioCity, Pennyfoot Street, Nottingham NG1 1GF, UK Tel: 0115 941 5401 Fax: 0115 924 2788 Email: info@sygnaturediscovery.com Website: www.sygnaturediscovery.com Contact: Dr Paul Clewlow

Sygnature Discovery is the UK’s largest independent provider of integrated drug discovery expertise, operating out of a fully enabled facility with the most advanced laboratories and technologies. Core capabilities include medicinal chemistry, in vitro bioscience, computational sciences and informatics, DMPK and protein crystallography. Sygnature undertakes complete drug discovery programmes and hit finding, hit‑to‑lead and lead optimisation projects. Over 160 experienced and highly qualified scientists utilise novel technologies and innovative ways of working that ensures delivery on the most complex research projects.

www.onenucleus.com | 137


Silver Members S

SynbiCITE Imperial College Incubator, Level 1 Bessemer Building, Imperial College, London SW7 2AZ, UK Website: www.synbicite.com

SynbiCITE is a pioneering Innovation and Knowledge Centre (IKC) dedicated to promoting the adoption and use of synthetic biology by industry. The IKC is an internationally recognised lead centre in industrialising synthetic biology research giving the UK a globally renowned national resource of interacting partners from across the UK’s leading academic institutions, industry and business. SynbiCITE is focused at Imperial College London and is, with our partners, accelerating the commercialisation of world‑class science and the emerging technologies encompassed by synthetic biology into new products, tools, processes and services.

Synergy Health Moray Road, Elgin Industrial Estate, Swindon SN2 8XS, UK Website: www.pharma‑labservices.com Contact: Allan Malcolm

Combining over half a century of experience in pharmaceutical product testing with STERIS laboratories (formerly Synergy Health), and a market leading position in medical device sterilisation, STERIS laboratories offer internationally recognised centres of excellence in pharmaceutical and medical device testing. Honesty and integrity are essential in building relationships that benefit our customers, and we build local relationships with global support in the areas of regulations, experience and standards. STERIS offers the total service offering, and is a flexible partner in product testing services in accordance with cGMP that will help your business to succeed.

Target to Treatment Consulting Ltd Stevenage Bioscience Catalyst, Gunnels Wood Road, Stevenage SG1 2FX, UK Tel: 07900 224 742 Email: paulinelukey@target2treatment.com Contact: Pauline T. Lukey

Target to Treatment Consulting Ltd provides expert advice on drug discovery and development, supported by 20 years of experience in the pharmaceutical industry. Areas of particular expertise are translational science and clinical trials in the fields of tuberculosis, autoimmune disease and fibrosis. Examples include: use of biomarkers (soluble, cellular and bioimaging markers), assessment of risk/benefit, smart study design and translation from preclinical work into the clinic.

Taylor Vinters Merlin Place, Milton Road, Cambridge CB4 0DP, UK Tel: 01223 423 444 Email: info@taylorvinters.com Website: www.taylorvinters.com Contact: Patrick Farrant

Taylor Vinters is a leading international law firm, supporting innovative businesses and entrepreneurially minded people to make great things happen. We understand that our clients are not only looking for a focus on their legal issues but also strong commercial acumen from their legal partner. We help our clients manage risk, make informed decisions and leverage networks to achieve their personal and business goals. We are excited by our clients, how their organisations and lives progress and how we can use our experience, networks and technical expertise to support them.

TCF Consulting SPRL Rue JB Colyns 24, B‑1050 Brussels, Belgium Website: www.tcfconsulting.com

138 | One Nucleus Directory 2017

Strategic life science cross‑border business consultancy focusing on technology commercialisation with special emphasis on start‑up dynamics and establishing platforms for value delivery (business planning, IP strategy, fundraising, project planning, implementation and commercialisation). Full or part‑time executive, non‑executive, advisory or training roles taken on. In partnership with North Carolina‑based Technology Commercialisation Group (TCG) LLC, sourcing and execution of US/European strategic business development, M&A and licensing transactions.


Silver Members T

Telensa Limited Plextek Building, London Road, Great Chesterford CB10 1NY, UK Fax: 01799 533 337 Website: www.telensa.com

The Ann Hayes Consultancy Buntingford, Hertfordshire, UK Tel: 07850 054 279 Email: annghayes2016@gmail.com Contact: Dr Ann Hayes

Dr Ann Hayes provides consulting advice to pharmaceutical and biotechnology companies, and venture capitalists in drug discovery (from early research through to clinical proof of concept), CNS diseases and pain, digital health, portfolio management and company strategy. Ann has 22 years’ experience of working for large pharma (GSK, 1978 to 2001), where she was a director in drug discovery, and subsequently many years of experience of consulting for the small pharma/ biotechnology/digital health industry (2001 to the present). Ann has also co‑founded three companies and sat on numerous boards, both main boards and advisory boards.

The Communications Strategy Group Inc. 42 Front Street, Marblehead, Massachusetts 01945, USA Tel: +1 781 631 3117 Email: edagne@comstratgroup.com Website: www.comstratgroup.com Contact: Edward D Agne

The Communications Strategy Group Inc. is a US‑based consultancy providing corporate/financial communications and business development services to the life sciences, biotech and medical technology sectors. The firm assists and advises UK/ EU companies seeking to expand to the US and provides corporate mentoring. CSG maintains strategic alliances with Instinctif Partners, London, and Cabinet Privé de Conseil s.a., Geneva.

The Institute of Cancer Research Enterprise Unit, 15 Cotswold Road, Belmont, Sutton, Surrey SM2 5NG, UK Tel: 020 8722 4030 Email: enterprise@icr.ac.uk Website: www.icr.ac.uk Contact: Dr Angela Kukula

The Institute of Cancer Research, London, is one of the world’s most influential cancer research institutes, with an outstanding record of achievement dating back more than 100 years. The ICR is led by our Chief Executive and President, Professor Paul Workman – an expert in cancer drug discovery. We lead the world at isolating cancer‑related genes and discovering new targeted cancer drugs. Together with our hospital partner The Royal Marsden, we are rated in the top four centres for cancer research and treatment worldwide.

Theradex (Europe) Ltd 2nd Floor, The Pinnacle, Station Way, Crawley, West Sussex RH10 1JH, UK Tel: 01293 510 319 Website: www.theradex.com

With over 30 years of experience as a leading oncology CRO, we are experts in the emerging use of therapeutics, diagnostics and medical devices. Theradex maintains its expertise through continuous interactions with oncology leaders in regulatory, academic and clinical arenas, to transition your products from lab to first in man and beyond. Born from a unique partnership with the National Cancer Institute, with operations in Europe and the USA, Theradex offers both scientific expertise, a full‑time oncologist on staff, and cancer clinical research management tools to efficiently manage your trial and share emerging data with you on a real time basis.

www.onenucleus.com | 139


Silver Members T

Tier 2 Consulting Ltd Business & Technology Centre, Bessemer Drive, Stevenage, Hertfordshire SG1 2DX, UK Tel: 01438 310 124 Email: info@tier2consulting.com Contact: Chris Ellis

Tier 2 Consulting has over 14 years’ experience in creating software for compliant environments with specific knowledge of computer system validation (CSV) requirements for FDA CFR Part 11 compliance, as evidenced by our work with GSK and 14M Genomics. We have a proprietary document control ‘product’, ARENA – a configurable, web‑based document control platform based on open industry standards to provide resilience and scalability. ARENA is ideal for early stage pharmaceutical and biotech company compliance needs. ARENA provides security and control over all phases of an electronic document’s life cycle at £6995 per year for a five workflow user licence.

Trade and Investment Queensland – London Australia Centre, Strand, London WC2B 4LG, UK Tel: 020 7420 8775 Fax: 020 7420 8770 Email: pauline.shearman@tiq.qld.gov.au Website: www.tiq.qld.gov.au Contact: Pauline Shearman

Queensland is a producer of high quality, innovative therapeutic health products with the life sciences sector forecast to be worth $20 billion and employ 16,000 by 2025. The Queensland Government’s Advance Queensland $180m programme will bring together entrepreneurs, industry, universities and government to work collaboratively to translate these innovations into new businesses. Queensland life sciences organisations operate across: agriculture, animal health, environment, human healthcare, industrial and marine biotechnology. TIQ aims to: increase contacts with scientific, business and research professionals in the UK and Europe; increase interaction with financial and venture capital sectors; and identify new business and investment opportunities. www.tiq.qld.gov.au.

TranScrip 400 Thames Valley Park Drive, Thames Valley Park, Reading RG6 1PT, UK Tel: 0118 963 7846 Fax: 0118 963 7497 Email: paul.branthwaite@transcrip‑partners.com Website: www.transcrip‑partners.com Contact: Paul Branthwaite

TranScrip is a trusted partner in providing strategic leadership and operational capacity for over 100 companies globally. Our clients include 20 of the top 50 pharmaceutical and many smaller biopharma companies. TranScrip supports the development and life cycle management of biopharmaceutical products. We provide expertise, resourcing and strategic oversight from translational medicine to successful registration and market access. Expert partners from pre‑inception to post‑patent.

Trifermed London Limited 9 Devonshire Square, London EC2M 4YF, UK Email: info@trifermed.com Website: www.trifermed.com Contact: Sergi Trilla

Trifermed was born in 2002 as a contract business development organisation, which is an organisation that provides support to the pharmaceutical, biotechnology and medical technologies industries in the form of business development services outsourced on a contract basis.

TTP Group plc Melbourn Science Park, Cambridge Road, Melbourn, Royston SG8 6EE, UK Tel: 01763 262 626 Email: enquiries@ttp.com Website: www.ttpgroup.com

140 | One Nucleus Directory 2017

TTP Group plc comprises four primary businesses: The Technology Partnership plc – a technology and product development company in areas as diverse as biotechnology, medical devices, instrumentation, communications, digital printing, consumer and industrial products, cleantech and security systems; TTP LabTech – an innovator and manufacturer of life science laboratory instrumentation; Tonejet – a break‑through digital printing business with a focus on industrial and commercial metal and foil printing; and Melbourn Science Park – the company that owns the business park where TTP Group businesses are located.


Silver Members U

TTS Ltd 1 Highlever Road, London W10 6PP, UK Tel: 07815 717 862 Email: morris@ttsglobalinitiative.com Website: www.ttsglobalinitiative.com Contact: Dr Morris S Berrie

Founded in 2007, TTS Global Initiative is an organisation that facilitates business understanding and consequently deal flow in the early stage start‑up/SME biotech sector. It has one primary objective: to foster innovation by accelerating the translation of world‑class life sciences and biomedical research from the lab to the patient and the market. Functioning as a think tank and action committee, TTS offers a wealth of expertise through hosting four exclusive interlinked annual summits in Europe, North America, Latin America and Australia. TTS is also currently involved in two EU Horizon 2020 projects.

Tusk Therapeutics Ltd Stevenage Bioscience Catalyst, Gunnels Wood Road, Stevenage SG1 2FX, UK Email: kevin.moulder@tusktherapeutics.com Contact: Kevin Moulder

Tusk Therapeutics Ltd is harnessing the power of the innate and adaptive immune system to fight cancer. We are establishing a diversified pipeline of antibodies against a selection of both novel and validated immuno‑oncology targets that play an important role in the immune response to cancer.

UCL The Network Building, 97 Tottenham Court Road, London W1T 4TP, UK Tel: 020 7679 9000 Fax: 020 7679 9838 Email: info@uclb.com Website: www.uclb.com Contact: Emma Alam

UCLB is a leading technology commercialisation company that supports research and innovations arising from UCL, one of the UK’s top research‑led universities. UCLB has a successful track record and a strong reputation for identifying and protecting promising new technologies and innovations from UCL academics. It invests directly in development projects to maximise the potential of the research and manages the commercialisation process of technologies from the laboratory to market. UCLB supports UCL’s Grand Challenges of increasing UCL’s positive impact on and contribution to global health, sustainable cities, intercultural interaction and human wellbeing.

UKSPA Chesterford Research Park, Little Chesterford, Essex CB10 1XL, UK Tel: 01799 532 050 Fax: 01799 532 049 Email: info@ukspa.org.uk Website: www.ukspa.org.uk Contact: Jim Duvall

The United Kingdom Science Park Association has been supporting science park, innovation centre and incubator development since 1984, and now has around 115 science parks, innovation centres and incubators in membership. Our members accommodate around 4000 companies that employ around 70,000 highly qualified staff, and turnover in the region of £5.5bn per annum. UKSPA organises events and delivers good practice and staff development programmes as well as information, advice and advocacy for the sector. 2017 will see UKSPA expand its offering to incubators to include the UKSPA INSPIRE Development, Monitoring and Accreditation process and the Inspire Certificate in Business Incubator Management.

University of Cambridge Hauser Forum, 3 Charles Babbage Road, Cambridge CB3 0GT, UK Tel: 01223 760 339 Fax: 01223 763 753 Email: enquiries@enterprise.cam.ac.uk Website: www.enterprise.cam.ac.uk Contact: Dr Iain Thomas

Cambridge Enterprise Limited is a wholly owned subsidiary of the University of Cambridge, responsible for the commercialisation of university intellectual property. Activities include management and licensing of intellectual property and patents, proof of concept funding, and support for university staff and research groups wishing to provide expert advice or facilities to public and private sector organisations. Cambridge Enterprise provides access to angel and early stage capital through the Cambridge Enterprise Seed Funds, University of Cambridge Enterprise Funds, Cambridge Innovation Capital and Cambridge Enterprise Venture Partners. Cambridge Enterprise also offers business planning, mentoring and other related programmes.

www.onenucleus.com | 141


Silver Members U

University of Essex Research and Enterprise Office, Wivenhoe Park, Colchester, Essex CO4 3SQ, UK Tel: 01206 872 922 Email: business@essex.ac.uk Website: www.essex.ac.uk Contact: Dr Kirstie Cochrane

The University of Essex ranks in the top 20 UK universities for research excellence. Our biological sciences expertise ranges through molecular biophysics, environmental biology, molecular medicine and sports science. Currently, we have interesting technologies in fields such as biomarkers, bioremediation and plant yield improvement. Our schools’ expertise spans the molecular, cellular and whole organism levels and encompasses microbial, plant and mammalian systems. The Essex Biomedical Sciences Institute is also fostering collaboration between academics at the university and a number of hospital NHS trusts across the region. The university is committed to working with external organisations to promote our science excellence.

University of Leicester – Enterprise & Business Development Office Fielding Johnson Building, University Road, Leicester LE1 7RH, UK Tel: 0116 223 1718 Email: lga4@le.ac.uk Website: www.le.ac.uk Contact: Lucille Alexander

The University of Leicester is a research intensive university with an impressive track record in cutting‑edge research. Ranked among the top 1 per cent of universities worldwide by the THE World University Rankings and in the top 100 leading international universities, we also work in collaboration with the University Hospital Trust Leicester, industry and the public sector. Leicester has recently been awarded a NIHR Biomedical Research Center encompassing cardiovascular, respiratory plus diet, lifestyle and physical activity and precision medicine. Leicester has an experimental cancer medicine centre and recently launched its new flagship research institutes in precision medicine and structural and chemical biology.

UVP Ltd (Ultra‑Violet Products Ltd) Unit 1, Trinity Hall Farm Estate, Nuffield Road, Cambridge, Cambridgeshire CB4 1TG, UK Tel: 01223 420 022 Fax: 01223 420 561 Email: uvp@uvp.co.uk Website: www.uvp.com

Ultra-Violet Products Ltd (an Analytik Jena company) offers application-specific solutions for gel documentation, chemiluminescent, fluorescent and colorimetric imaging, plus micro/macro fluorescent protein in vivo imaging. Systems range from the standalone UVP BioDoc-It2 System to the advanced UVP ChemStudio PLUS and iBox Series, including the eLite Multispectral Source. Other products include UV lamps, transilluminators, PCR workstations, UV crosslinkers, UV incubators, hybridisation ovens, UV cabinets, UV intensity metres and light sources. UVP Ltd also sells Analytik Jena branded products from the Life Science Portfolio in the UK and the Republic of Ireland.

Venner Shipley LLP 200 Aldersgate, London EC1A 4HD, UK Tel: 020 7600 4212 Fax: 020 7600 4188 Email: aelend@vennershipley.co.uk Website: www.vennershipley.co.uk Contact: Dr Allie Elend

Venner Shipley is a leading firm of European patent and trademark attorneys and lawyers, representing a broad range of clients, including major domestic and international corporations, SMEs, universities and individual inventors. We provide a full range of services covering patents, trademarks, designs and copyright, domain names and all other aspects of intellectual property, in all areas of science, technology and design. We have a particularly strong team serving life science and healthcare companies. Our services extend beyond rights protection, to enforcement and licensing activities. We have offices in London, Cambridge, Guildford, Manchester and Munich.

Vetter Pharma International GmbH Eywiesenstrasse 5, D-88212 Ravensburg, Germany Tel: +49 7513 7000 Fax: +49 7513 7004 000 Email: info@vetter-pharma.com Website: www.vetter-pharma.com

142 | One Nucleus Directory 2017

Vetter is a leading contract development and manufacturing organisation (CDMO) which specialises in the aseptic filling of syringes, cartridges and vials. The company has extensive experience with biologics and other complex compounds, including monoclonal antibodies, peptides, interferons and vaccines. Collaborating with pharma/biotech clients worldwide, Vetter supports products from preclinical development through to global market supply. Through its USA and European facilities, Vetter Development Service provides state-of-the-art support for early-stage products, with seamless transfer at Phase III to Vetter Commercial Manufacturing for large-scale production. The company offers state-of-the-art technology and innovative processes to promote product quality and maximise API yield..


Londonâ&#x20AC;&#x2122;s premier Life Science & Healthcare networking conference

genesis 2017 14 December 2017 QE II Centre Westminster, London, UK

#ongc17 genesisconference.com


Silver Members W

Wallder Limited Vectis House, 7 Nightingale Lane, St Albans, Hertfordshire AL1 1DX, UK Tel: 01727 822 855 Email: info@wallder.com Website: www.wallder.com Contact: David Wallder / Lesley House

Wallder Limited offers two services. We help build boards and senior management teams in life-science companies, encompassing diagnostics, medtech and therapeutics. Half of our assignments are for non-executive chairmen and directors. The remainder are for members of the senior management team. Our typical salary range is £80,000 to £200,000. We are UK-based but work globally. We invest in early stage life science companies where we think the people, investor base, technology and image are right. So, we both find and invest in good people – board and senior management. In early stage companies we help to get our clients over the line and to healthy exits, and in later stage companies we help to ensure continued growth and profitability.

Wickham Laboratories Limited Hoeford Point, Barwell Lane, Gosport, Hampshire PO13 0AU, UK Tel: 01329 226 600 Email: mail@wickhamlabs.co.uk Website: www.wickhamlabs.co.uk Contact: John McKenzie

Wickham Laboratories Ltd is a trusted name in the pharmaceutical and medical device industries as a GMP/GLP compliant laboratory with over 50 years of experience in contract testing, research and consultancy. We maintain only the highest standard of quality at all stages while providing rapid turnaround for both routine testing and bespoke one‑off projects. Whether assisting a start‑up company demonstrating proof of concept, or working with a global medical device manufacturer, our expert technicians recognise the importance of delivering an exceptional service by taking the time with every client to fully understand their individual requirements.

Withers & Rogers LLP 4 More London Riverside, London SE1 2AU, UK Tel: 020 7940 3600 Fax: 020 7378 9680 Email: marketing@withersrogers.info Website: www.withersrogers.com Contact: Adrian Tombling

Withers & Rogers LLP is a leading intellectual property law firm providing a comprehensive range of services, including the core offering of processing patent, registered design and trademark applications through to grant, and representation in oppositions and appeals. Our life sciences and chemistry group comprises 14 European patent attorneys and trainee patent attorneys and is one of the largest in Europe, with a depth of expertise and experience in the chemical, biochemical and pharmaceutical industries, as well as in academic research. There are a further three principal practice groups: advanced engineering; electronics, computing and physics; and trademark.

Work Area Ltd 9 Romney Road, Banbury, Oxfordshire OX16 1YA, UK Tel: 01295 982 008 Email: neil@workarealtd.com Website: www.workarealtd.com Contact: Neil Hancox

Centrally based in Banbury, Oxfordshire, Work Area Ltd offers a range of products associated with health, safety and wellbeing within the working environment. Our aim is to offer a friendly, efficient and honest service, excellent product availability and very competitive pricing. Our products have been selected directly from UK manufacturers and include: chemical storage cabinets, acid storage cabinets, solvent/flammables storage cabinets, workplace lockers, laboratory seating, cleanroom seating and office seating. Why not let us improve your work area?

WuXi AppTec UK Ltd United Kingdom Tel: 07803 124 321 Email: dave_madge@wuxiapptec.com Website: www.wuxiapptec.com Contact: Dr David Madge

144 | One Nucleus Directory 2017

WuXi AppTec is a leading open‑access R&D capability and technology platform with operations in China, USA, Germany and Iceland. As an innovation‑driven and customer‑focused company, WuXi AppTec provides a broad and integrated portfolio of services to help our partners shorten the discovery and development time and lower the cost of drug and medical device R&D through cost‑effective and efficient solutions. With its industry‑leading capabilities in small molecule, biologics, cell therapy and gene therapy, medical device testing, and molecular testing and genomics, WuXi is enabling more than 2000 collaborators from more than 30 countries to bring innovative healthcare products to patients.


Silver Members Z

Yusen Logistics UK GP1 Grange Park, Cheaney Drive, Northampton NN4 5FB, UK Tel: 07719 408 757 Email: frank.packman@uk.yusen‑logistics.com Website: www.yusen‑logistics.com/en/europe/ united‑kingdom Contact: Frank Packman

Yusen Logistics provides a fully GDP‑compliant E2E healthcare supply chain across Europe through a single point of contact, via our dedicated healthcare European Control Tower. Our customers benefit from years of experience and knowledge and award‑winning services. We offer customers the opportunity for improved service and quality, whilst reducing cost by providing a fully GDP‑compliant European network. These include a European temperature controlled road network, offering LTL and FTL solutions, as well as global temperature controlled via AIR or SEA, as well warehousing and final mile solutions, which are fully managed through the same Control Tower.

Zen medical science consultancy 45 Lexham Gardens, Kensington and Chelsea, London W8 5JT, UK Tel: 07837 336 068 Email: zenmed.consultancy@gmail.com / dr_joanna_han@yahoo.com Contact: Ziqun (Joanna) Han

Zen medical consultancy provides consultation on: global (more focus on EU and China) regulatory intelligence, PV intelligence, clinical trial strategy and submission strategy. It also facilitates and provides due diligence on potential investments from China on pharma/biotech companies.

www.onenucleus.com | 145


Advertisers’ Index

Advertisers’ Index APL ASSM (Asset and Systems Support Management) Asterand Bioscience UK BioPark Chesterford Research Park Cisbio Bioassays EMBL‑EBI Europa Bioproducts Ltd Harlow Council Imperial College London ThinkSpace INC Research (UK) Ltd InterFocus Ltd INVEST Essex LabKey (UK) Ltd Life Sciences Hub Wales Markel UK Limited Nature Publishing Group Nexus IE Ltd / GB Innomech Ltd Norwich Research Park Pharmidex Pharmaceutical Services Ltd Potter Clarkson LLP STARLAB (UK) Ltd Wickham Laboratories Limited

146 | One Nucleus Directory 2017

46 78 46 78 7 101 34 101 22 5 106 78, 106 105 106 Inside Back Cover Inside Front Cover Outside Back Cover 111 105 38 11 21 11


Life Sciences Hub Wales is the nerve centre of a vibrant Welsh Life Sciences eco-system. Bringing together academic, business, clinical, professional services, government and funding organisations the Hub provides a commercially-driven resource for the Life Sciences sector. The Hub supports Life Sciences businesses with start-up guidance, precision partnering, referrals to service providers, funding and investment opportunities, and NHS Wales engagement. Whilst also providing access to dedicated facilities, events, promotion, and networking opportunities. Discover more about this dynamic sector and its opportunities by working with the Hub. Get connected, inspired and accelerated with Life Sciences in Wales. Tel: +44 (0)29 2046 7030 Email: hello@lifescienceshubwales.com

lifescienceshubwales. com


Want to discover the right jobseekers? Recruit talented science professionals with Naturejobs Naturejobs is the global career resource and recruitment platform for scientists from Nature, the international weekly journal of science. • Online Job Packages – with proven ways of increasing the effectiveness of your job post • Employer Branding – showcase your organization via sponsored blog posts, podcasts and webcasts • Naturejobs Newsletter – reach jobseekers via our twice-monthly newsletter to over 215,000 registered recipients • Naturejobs Career Expo – meet jobseekers face-to-face at our global career fair and conference series

naturejobs.com

Find out more about Naturejobs: T(UK): +44 (0)20 7843 4961

T(US): +1 800 989 771

E: naturejobs@nature.com

One Nucleus Members’ Directory 2017  

One Nucleus Members’ Directory 2017

Read more
Read more
Similar to
Popular now
Just for you