Medical Publication

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Biopharmaceutical Dealmaking Exhibit 2

Top Ten Pharmaceutical Acquisitions Of 2010*

Acquirer

Acquired

Primary assets gained through the deal

March

Teva

ratiopharm

Significant share of the European generics market

4,989

June

Grifols

Talecris

Plasma-derived therapeutics

4,000

July

Reckitt Benckiser

SSL International

Personal care products, plus opportunities for expansion into Asia

3,961

June

BASF

Cognis

Specialty chemicals, dietary supplements, APIs , and drug delivery agents

3,823

May

Abbott

Piramal

350 branded generics; the deal makes Abbott the largest drug producer in India

3,720

Oct.

Pfizer

King

Specialty pharmaceuticals with a focus on pain management

3,561

June

Celgene

Abraxis

Cancer drug Abraxane (paclitaxel formulation) and nab nanoparticle delivery technology

March

Astellas

OSI

EGFR inhibitor Tarceva for pancreatic and non-small cell lung cancers; oncology pipeline

3,519

June

Valeant

Biovail (reverse merger – Biovail has a 50.5% stake in the combined company, which keeps the Valeant name)

Neurology and dermatology drugs and expanded presence in North America and emerging markets

3,272

Sept.

Johnson & Johnson

Crucell

Infectious disease vaccines and monoclonal antibodies; the deal makes J&J the sixth-largest vaccines producer

2,167

Those highlighted were nominees for IN VIVO Blog’s 2010 Deal of the Year. *List includes biopharma and OTC/personal care companies; excludes Research/Analytical companies. SOURCE: Elsevier’s Strategic Transactions

8

Potential Deal Value ($ millions)

Date

| January 2011 | IN VIVO: The Business & Medicine Report | www.ElsevierBI.com

3,559 (consists of $2.9bn in cash and Celgene stock, plus $650mm in tradable CVRs tied to Abraxane)


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